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Table of Contents

April 17, 2007; 104 (16)  [Index By Author]  [Cover Photo]  [Masthead (PDF)]

FROM THE COVER

Feature Articles: Molecular control of cholesterol feedback (A)

Feature Articles: Molecular control of cholesterol feedback (B)

Jawbone sets Australopithecus apart from humans

Direct reduced model of the Euler equations

St. Lawrence River caused Big Freeze

Nanotube liquid crystal aligns membrane proteins

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down arrow THIS WEEK IN PNAS

down arrow EDITORIAL

down arrow COMMENTARIES

down arrow FEATURE ARTICLES

down arrow PHYSICAL SCIENCES
    Applied Mathematics
    Chemistry
    Environmental Sciences
    Geology
    Statistics
    Sustainability Science

down arrow SOCIAL SCIENCES
    Anthropology

down arrow BIOLOGICAL SCIENCES
    Anthropology
    Applied Biological Sciences
    Biochemistry
    Biophysics
    Cell Biology
    Developmental Biology
    Ecology
    Evolution
    Genetics

    Immunology
    Medical Sciences
    Microbiology
    Neuroscience
    Pharmacology
    Physiology
    Plant Biology

down arrow CORRECTIONS

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up arrow THIS WEEK IN PNAS

In This Issue
PNAS 2007 104: 6493-6494. [Full Text] [PDF]  

up arrow EDITORIAL

Randy Schekman
Introducing Feature Articles in PNAS
PNAS 2007 104: 6495. [Extract] [Full Text] [PDF]  

up arrow COMMENTARIES

Randy Schekman
How sterols regulate protein sorting and traffic
PNAS 2007 104: 6496-6497; published online before print April 11 2007, 10.1073/pnas.0701774104 [Extract] [Full Text] [PDF]  
* See companion article on page 6511
* See companion article on page 6519

Thomas Y. Hou
Organized structures, memory, and the decay of turbulence
PNAS 2007 104: 6498-6499; published online before print April 11 2007, 10.1073/pnas.0700639104 [Extract] [Full Text] [Figures Only] [PDF]  
* See companion article on page 6527

Steven M. Colman
Conventional wisdom and climate history
PNAS 2007 104: 6500-6501; published online before print April 13 2007, 10.1073/pnas.0701952104 [Extract] [Full Text] [Figures Only] [PDF]  
* See companion article on page 6556

Charles R. Sanders
Visiting order on membrane proteins by using nanotechnology
PNAS 2007 104: 6502-6503; published online before print April 9 2007, 10.1073/pnas.0701950104 [Extract] [Full Text] [Figures Only] [PDF]  
* See companion article on page 6644

up arrow FEATURE ARTICLES
Arun Radhakrishnan, Yukio Ikeda, Hyock Joo Kwon, Michael S. Brown, and Joseph L. Goldstein
From the Cover: Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: Oxysterols block transport by binding to Insig
PNAS 2007 104: 6511-6518; published online before print April 11 2007, 10.1073/pnas.0700899104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Text] OPEN ACCESS ARTICLE  
* See Commentary on page 6496

Li-Ping Sun, Joachim Seemann, Joseph L. Goldstein, and Michael S. Brown
From the Cover: Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: Insig renders sorting signal in Scap inaccessible to COPII proteins
PNAS 2007 104: 6519-6526; published online before print April 11 2007, 10.1073/pnas.0700907104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Text] OPEN ACCESS ARTICLE  
* See Commentary on page 6496

up arrow PHYSICAL SCIENCES

Applied Mathematics

Ole H. Hald and Panagiotis Stinis
From the Cover: Optimal prediction and the rate of decay for solutions of the Euler equations in two and three dimensions
PNAS 2007 104: 6527-6532; published online before print April 11 2007, 10.1073/pnas.0700084104 [Abstract] [Full Text] [Figures Only] [PDF]  
* See Commentary on page 6498

Simone Pigolotti, Sandeep Krishna, and Mogens H. Jensen
Oscillation patterns in negative feedback loops
PNAS 2007 104: 6533-6537; published online before print April 5 2007, 10.1073/pnas.0610759104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Chemistry

Andrew D. Hughes and Eric V. Anslyn
A cationic host displaying positive cooperativity in water
PNAS 2007 104: 6538-6543; published online before print April 9 2007, 10.1073/pnas.0609144104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Percy H. Carter, Rui-Qin Liu, William R. Foster, Joseph A. Tamasi, Andrew J. Tebben, Margaret Favata, Ada Staal, Mary Ellen Cvijic, Michele H. French, Vanessa Dell, Donald Apanovitch, Ming Lei, Qihong Zhao, Mark Cunningham, Carl P. Decicco, James M. Trzaskos, and Jean H. M. Feyen
Discovery of a small molecule antagonist of the parathyroid hormone receptor by using an N-terminal parathyroid hormone peptide probe
PNAS 2007 104: 6846-6851; published online before print April 11 2007, 10.1073/pnas.0605125104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Environmental Sciences

Christopher Oze, Dennis K. Bird, and Scott Fendorf
Genesis of hexavalent chromium from natural sources in soil and groundwater
PNAS 2007 104: 6544-6549; published online before print April 9 2007, 10.1073/pnas.0701085104 [Abstract] [Full Text] [Figures Only] [PDF]  

G. Bala, K. Caldeira, M. Wickett, T. J. Phillips, D. B. Lobell, C. Delire, and A. Mirin
Combined climate and carbon-cycle effects of large-scale deforestation
PNAS 2007 104: 6550-6555; published online before print April 9 2007, 10.1073/pnas.0608998104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Geology

Anders E. Carlson, Peter U. Clark, Brian A. Haley, Gary P. Klinkhammer, Kathleen Simmons, Edward J. Brook, and Katrin J. Meissner
From the Cover: Geochemical proxies of North American freshwater routing during the Younger Dryas cold event
PNAS 2007 104: 6556-6561; published online before print April 9 2007, 10.1073/pnas.0611313104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  
* See Commentary on page 6500

Statistics

D. Sornette, A. B. Davis, K. Ide, K. R. Vixie, V. Pisarenko, and J. R. Kamm
Algorithm for model validation: Theory and applications
PNAS 2007 104: 6562-6567; published online before print April 9 2007, 10.1073/pnas.0611677104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Sustainability Science

James Battin, Matthew W. Wiley, Mary H. Ruckelshaus, Richard N. Palmer, Elizabeth Korb, Krista K. Bartz, and Hiroo Imaki
Projected impacts of climate change on salmon habitat restoration
PNAS 2007 104: 6720-6725; published online before print April 5 2007, 10.1073/pnas.0701685104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

up arrow SOCIAL SCIENCES

Anthropology

Mary E. D. Pohl, Dolores R. Piperno, Kevin O. Pope, and John G. Jones
Microfossil evidence for pre-Columbian maize dispersals in the neotropics from San Andrés, Tabasco, Mexico
PNAS 2007 104: 6870-6875; published online before print April 10 2007, 10.1073/pnas.0701425104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

up arrow BIOLOGICAL SCIENCES

Anthropology

Yoel Rak, Avishag Ginzburg, and Eli Geffen
From the Cover: Gorilla-like anatomy on Australopithecus afarensis mandibles suggests Au. afarensis link to robust australopiths
PNAS 2007 104: 6568-6572; published online before print April 10 2007, 10.1073/pnas.0606454104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Hong Shang, Haowen Tong, Shuangquan Zhang, Fuyou Chen, and Erik Trinkaus
An early modern human from Tianyuan Cave, Zhoukoudian, China
PNAS 2007 104: 6573-6578; published online before print April 6 2007, 10.1073/pnas.0702169104 [Abstract] [Full Text] [Figures Only] [PDF]  

Applied Biological Sciences

Özgür Sahin, Christian Löbke, Ulrike Korf, Heribert Appelhans, Holger Sültmann, Annemarie Poustka, Stefan Wiemann, and Dorit Arlt
Combinatorial RNAi for quantitative protein network analysis
PNAS 2007 104: 6579-6584; published online before print April 9 2007, 10.1073/pnas.0606827104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE  

Susan Hafenstein, Laura M. Palermo, Victor A. Kostyuchenko, Chuan Xiao, Marc C. Morais, Christian D. S. Nelson, Valorie D. Bowman, Anthony J. Battisti, Paul R. Chipman, Colin R. Parrish, and Michael G. Rossmann
Asymmetric binding of transferrin receptor to parvovirus capsids
PNAS 2007 104: 6585-6589; published online before print April 9 2007, 10.1073/pnas.0701574104 [Abstract] [Full Text] [Figures Only] [PDF]  

Biochemistry

Arun Radhakrishnan, Yukio Ikeda, Hyock Joo Kwon, Michael S. Brown, and Joseph L. Goldstein
From the Cover: Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: Oxysterols block transport by binding to Insig
PNAS 2007 104: 6511-6518; published online before print April 11 2007, 10.1073/pnas.0700899104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Text] OPEN ACCESS ARTICLE  
* See Commentary on page 6496

Li-Ping Sun, Joachim Seemann, Joseph L. Goldstein, and Michael S. Brown
From the Cover: Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: Insig renders sorting signal in Scap inaccessible to COPII proteins
PNAS 2007 104: 6519-6526; published online before print April 11 2007, 10.1073/pnas.0700907104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Text] OPEN ACCESS ARTICLE  
* See Commentary on page 6496

Andrew D. Hughes and Eric V. Anslyn
A cationic host displaying positive cooperativity in water
PNAS 2007 104: 6538-6543; published online before print April 9 2007, 10.1073/pnas.0609144104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Peter Chien, Barrett S. Perchuk, Michael T. Laub, Robert T. Sauer, and Tania A. Baker
Direct and adaptor-mediated substrate recognition by an essential AAA+ protease
PNAS 2007 104: 6590-6595; published online before print April 9 2007, 10.1073/pnas.0701776104 [Abstract] [Full Text] [Figures Only] [PDF]  

Youngjun Kim, Matthew S. Gentry, Thurl E. Harris, Sandra E. Wiley, John C. Lawrence, Jr, and Jack E. Dixon
A conserved phosphatase cascade that regulates nuclear membrane biogenesis
PNAS 2007 104: 6596-6601; published online before print April 9 2007, 10.1073/pnas.0702099104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] [Online Correction to SI Methods]  

Ji-Won Park, Chan-Hee Kim, Jung-Hyun Kim, Byung-Rok Je, Kyung-Baeg Roh, Su-Jin Kim, Hyeon-Hwa Lee, Ji-Hwan Ryu, Jae-Hong Lim, Byung-Ha Oh, Won-Jae Lee, Nam-Chul Ha, and Bok-Luel Lee
Clustering of peptidoglycan recognition protein-SA is required for sensing lysine-type peptidoglycan in insects
PNAS 2007 104: 6602-6607; published online before print April 4 2007, 10.1073/pnas.0610924104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Nikolaus S. Trede, Jan Medenbach, Andrey Damianov, Lee-Hsueh Hung, Gerhard J. Weber, Barry H. Paw, Yi Zhou, Candace Hersey, Agustin Zapata, Matthew Keefe, Bruce A. Barut, Andrew B. Stuart, Tammisty Katz, Chris T. Amemiya, Leonard I. Zon, and Albrecht Bindereif
Network of coregulated spliceosome components revealed by zebrafish mutant in recycling factor p110
PNAS 2007 104: 6608-6613; published online before print April 6 2007, 10.1073/pnas.0701919104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Andrew A. Horwitz, El Bachir Affar, George F. Heine, Yang Shi, and Jeffrey D. Parvin
A mechanism for transcriptional repression dependent on the BRCA1 E3 ubiquitin ligase
PNAS 2007 104: 6614-6619; published online before print April 9 2007, 10.1073/pnas.0610481104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

Aaron R. Robart, Wooseok Seo, and Steven Zimmerly
Insertion of group II intron retroelements after intrinsic transcriptional terminators
PNAS 2007 104: 6620-6625; published online before print April 9 2007, 10.1073/pnas.0700561104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Joshua L. Wheatley and Todd Holyoak
Differential P1 arginine and lysine recognition in the prototypical proprotein convertase Kex2
PNAS 2007 104: 6626-6631; published online before print April 10 2007, 10.1073/pnas.0701983104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Akiko Koide, Ryan N. Gilbreth, Kaori Esaki, Valentina Tereshko, and Shohei Koide
High-affinity single-domain binding proteins with a binary-code interface
PNAS 2007 104: 6632-6637; published online before print April 9 2007, 10.1073/pnas.0700149104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Yaron Bogin, Carmit Ainey, Dvora Beach, and Deborah Yablonski
SLP-76 mediates and maintains activation of the Tec family kinase ITK via the T cell antigen receptor-induced association between SLP-76 and ITK
PNAS 2007 104: 6638-6643; published online before print April 9 2007, 10.1073/pnas.0609771104 [Abstract] [Full Text] [Figures Only] [PDF]  

Biophysics

Shawn M. Douglas, James J. Chou, and William M. Shih
From the Cover: DNA-nanotube-induced alignment of membrane proteins for NMR structure determination
PNAS 2007 104: 6644-6648; published online before print April 2 2007, 10.1073/pnas.0700930104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  
* See Commentary on page 6502

Reinhard Schweitzer-Stenner and Thomas J. Measey
The alanine-rich XAO peptide adopts a heterogeneous population, including turn-like and polyproline II conformations
PNAS 2007 104: 6649-6654; published online before print April 6 2007, 10.1073/pnas.0700006104 [Abstract] [Full Text] [Figures Only] [PDF]  

Haihong Wu and Juli Feigon
H/ACA small nucleolar RNA pseudouridylation pockets bind substrate RNA to form three-way junctions that position the target U for modification
PNAS 2007 104: 6655-6660; published online before print April 5 2007, 10.1073/pnas.0701534104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

M. F. Richter, J. Baier, T. Prem, S. Oellerich, F. Francia, G. Venturoli, D. Oesterhelt, J. Southall, R. J. Cogdell, and J. Köhler
Symmetry matters for the electronic structure of core complexes from Rhodopseudomonas palustris and Rhodobacter sphaeroides PufX
PNAS 2007 104: 6661-6665; published online before print April 6 2007, 10.1073/pnas.0611115104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Movies]  

Juha T. Huiskonen, Violeta Manole, and Sarah J. Butcher
Tale of two spikes in bacteriophage PRD1
PNAS 2007 104: 6666-6671; published online before print April 6 2007, 10.1073/pnas.0608625104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

J. Nathan Henderson, Hui-wang Ai, Robert E. Campbell, and S. James Remington
Structural basis for reversible photobleaching of a green fluorescent protein homologue
PNAS 2007 104: 6672-6677; published online before print April 9 2007, 10.1073/pnas.0700059104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Michael G. Malkowski, Erin Quartley, Alan E. Friedman, Julie Babulski, Yoshiko Kon, Jennifer Wolfley, Meriem Said, Joseph R. Luft, Eric M. Phizicky, George T. DeTitta, and Elizabeth J. Grayhack
Blocking S-adenosylmethionine synthesis in yeast allows selenomethionine incorporation and multiwavelength anomalous dispersion phasing
PNAS 2007 104: 6678-6683; published online before print April 10 2007, 10.1073/pnas.0610337104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Tables] OPEN ACCESS ARTICLE  

Cell Biology

Kathrin Kindsmüller, Peter Groitl, Barbara Härtl, Paola Blanchette, Joachim Hauber, and Thomas Dobner
Intranuclear targeting and nuclear export of the adenovirus E1B-55K protein are regulated by SUMO1 conjugation
PNAS 2007 104: 6684-6689; published online before print April 11 2007, 10.1073/pnas.0702158104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Vítezslav Bryja, Dietmar Gradl, Alexandra Schambony, Ernest Arenas, and Gunnar Schulte
beta-Arrestin is a necessary component of Wnt/beta-catenin signaling in vitro and in vivo
PNAS 2007 104: 6690-6695; published online before print April 10 2007, 10.1073/pnas.0611356104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Kiranmai Gumireddy, Fangxian Sun, Andres J. Klein-Szanto, Jonathan M. Gibbins, Phyllis A. Gimotty, Aleister J. Saunders, Peter G. Schultz, and Qihong Huang
In vivo selection for metastasis promoting genes in the mouse
PNAS 2007 104: 6696-6701; published online before print April 9 2007, 10.1073/pnas.0701145104 [Abstract] [Full Text] [Figures Only] [PDF]  

Eric A. Vitriol, Andrea C. Uetrecht, Feimo Shen, Ken Jacobson, and James E. Bear
Enhanced EGFP-chromophore-assisted laser inactivation using deficient cells rescued with functional EGFP-fusion proteins
PNAS 2007 104: 6702-6707; published online before print April 9 2007, 10.1073/pnas.0701801104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Developmental Biology

Yasuyuki S. Kida, Takayuki Sato, Kota Y. Miyasaka, Asami Suto, and Toshihiko Ogura
Daam1 regulates the endocytosis of EphB during the convergent extension of the zebrafish notochord
PNAS 2007 104: 6708-6713; published online before print April 5 2007, 10.1073/pnas.0608946104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Ai Khim Lim and Toshie Kai
Unique germ-line organelle, nuage, functions to repress selfish genetic elements in Drosophila melanogaster
PNAS 2007 104: 6714-6719; published online before print April 11 2007, 10.1073/pnas.0701920104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Ecology

James Battin, Matthew W. Wiley, Mary H. Ruckelshaus, Richard N. Palmer, Elizabeth Korb, Krista K. Bartz, and Hiroo Imaki
Projected impacts of climate change on salmon habitat restoration
PNAS 2007 104: 6720-6725; published online before print April 5 2007, 10.1073/pnas.0701685104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Evolution

Stanley A. Sawyer, John Parsch, Zhi Zhang, and Daniel L. Hartl
Inaugural Article by a Recently Elected Academy Member:
Inaugural Article: Prevalence of positive selection among nearly neutral amino acid replacements in Drosophila
PNAS 2007 104: 6504-6510; published online before print April 4 2007, 10.1073/pnas.0701572104 [Abstract] [Full Text] [Figures Only] [PDF]  

Love Dalén, Veronica Nyström, Cristina Valdiosera, Mietje Germonpré, Mikhail Sablin, Elaine Turner, Anders Angerbjörn, Juan Luis Arsuaga, and Anders Götherström
Ancient DNA reveals lack of postglacial habitat tracking in the arctic fox
PNAS 2007 104: 6726-6729; published online before print April 9 2007, 10.1073/pnas.0701341104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

J. R. Chasnov, W. K. So, C. M. Chan, and K. L. Chow
The species, sex, and stage specificity of a Caenorhabditis sex pheromone
PNAS 2007 104: 6730-6735; published online before print April 6 2007, 10.1073/pnas.0608050104 [Abstract] [Full Text] [Figures Only] [PDF]  

Laurent Lehmann, Laurent Keller, Stuart West, and Denis Roze
Group selection and kin selection: Two concepts but one process
PNAS 2007 104: 6736-6739; published online before print April 6 2007, 10.1073/pnas.0700662104 [Abstract] [Full Text] [PDF] [Supporting Information]  

Genetics

Simone Pigolotti, Sandeep Krishna, and Mogens H. Jensen
Oscillation patterns in negative feedback loops
PNAS 2007 104: 6533-6537; published online before print April 5 2007, 10.1073/pnas.0610759104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Andy J. Minn, Gaorav P. Gupta, David Padua, Paula Bos, Don X. Nguyen, Dimitry Nuyten, Bas Kreike, Yi Zhang, Yixin Wang, Hemant Ishwaran, John A. Foekens, Marc van de Vijver, and Joan Massagué
Lung metastasis genes couple breast tumor size and metastatic spread
PNAS 2007 104: 6740-6745; published online before print April 9 2007, 10.1073/pnas.0701138104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Stefan Krebs, Ivica Medugorac, Susanne Röther, Katja Strässer, and Martin Förster
A missense mutation in the 3-ketodihydrosphingosine reductase FVT1 as candidate causal mutation for bovine spinal muscular atrophy
PNAS 2007 104: 6746-6751; published online before print April 9 2007, 10.1073/pnas.0607721104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Tables]  

Jon Penterman, Daniel Zilberman, Jin Hoe Huh, Tracy Ballinger, Steven Henikoff, and Robert L. Fischer
DNA demethylation in the Arabidopsis genome
PNAS 2007 104: 6752-6757; published online before print April 4 2007, 10.1073/pnas.0701861104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE  

Robert R. Graham, Chieko Kyogoku, Snaevar Sigurdsson, Irina A. Vlasova, Leela R. L. Davies, Emily C. Baechler, Robert M. Plenge, Thearith Koeuth, Ward A. Ortmann, Geoffrey Hom, Jason W. Bauer, Clarence Gillett, Noel Burtt, Deborah S. Cunninghame Graham, Robert Onofrio, Michelle Petri, Iva Gunnarsson, Elisabet Svenungsson, Lars Rönnblom, Gunnel Nordmark, Peter K. Gregersen, Kathy Moser, Patrick M. Gaffney, Lindsey A. Criswell, Timothy J. Vyse, Ann-Christine Syvänen, Paul R. Bohjanen, Mark J. Daly, Timothy W. Behrens, and David Altshuler
Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus
PNAS 2007 104: 6758-6763; published online before print April 5 2007, 10.1073/pnas.0701266104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE  

Immunology

Jean da Silva Correia, Yvonne Miranda, Nikki Leonard, and Richard Ulevitch
SGT1 is essential for Nod1 activation
PNAS 2007 104: 6764-6769; published online before print April 9 2007, 10.1073/pnas.0610926104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

Scott J. Roberts, Bernice Y. Ng, Renata B. Filler, Julia Lewis, Earl J. Glusac, Adrian C. Hayday, Robert E. Tigelaar, and Michael Girardi
Characterizing tumor-promoting T cells in chemically induced cutaneous carcinogenesis
PNAS 2007 104: 6770-6775; published online before print April 5 2007, 10.1073/pnas.0604982104 [Abstract] [Full Text] [Figures Only] [PDF]  

Asier Sáez-Cirión, Christine Lacabaratz, Olivier Lambotte, Pierre Versmisse, Alejandra Urrutia, Faroudy Boufassa, Françoise Barré-Sinoussi, Jean-François Delfraissy, Martine Sinet, Gianfranco Pancino, Alain Venet for the Agence Nationale de Recherches sur le Sida EP36 HIV Controllers Study Group
HIV controllers exhibit potent CD8 T cell capacity to suppress HIV infection ex vivo and peculiar cytotoxic T lymphocyte activation phenotype
PNAS 2007 104: 6776-6781; published online before print April 11 2007, 10.1073/pnas.0611244104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures] OPEN ACCESS ARTICLE  

Medical Sciences

Filippo Acconcia, Christopher J. Barnes, Rajesh R. Singh, Amjad H. Talukder, and Rakesh Kumar
Phosphorylation-dependent regulation of nuclear localization and functions of integrin-linked kinase
PNAS 2007 104: 6782-6787; published online before print April 9 2007, 10.1073/pnas.0701999104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Marc Tischkowitz, Bing Xia, Nelly Sabbaghian, Jorge S. Reis-Filho, Nancy Hamel, Guilan Li, Erik H. van Beers, Lili Li, Tayma Khalil, Louise A. Quenneville, Atilla Omeroglu, Aletta Poll, Pierre Lepage, Nora Wong, Petra M. Nederlof, Alan Ashworth, Patricia N. Tonin, Steven A. Narod, David M. Livingston, and William D. Foulkes
Analysis of PALB2/FANCN-associated breast cancer families
PNAS 2007 104: 6788-6793; published online before print April 9 2007, 10.1073/pnas.0701724104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Tables]  

Abhinav Diwan, Andrew G. Koesters, Amy M. Odley, Suvarnamala Pushkaran, Christopher P. Baines, Benjamin T. Spike, Diedre Daria, Anil G. Jegga, Hartmut Geiger, Bruce J. Aronow, Jeffery D. Molkentin, Kay F. Macleod, Theodosia A. Kalfa, and Gerald W. Dorn, II
Unrestrained erythroblast development in Nix–/– mice reveals a mechanism for apoptotic modulation of erythropoiesis
PNAS 2007 104: 6794-6799; published online before print April 9 2007, 10.1073/pnas.0610666104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE  

Shenghai Huang, Jingjing Liang, Mengjie Zheng, Xinyi Li, Meiling Wang, Ping Wang, Difernando Vanegas, Di Wu, Bikram Chakraborty, Arthur P. Hays, Ken Chen, Shu G. Chen, Stephanie Booth, Mark Cohen, Pierluigi Gambetti, and Qingzhong Kong
Inducible overexpression of wild-type prion protein in the muscles leads to a primary myopathy in transgenic mice
PNAS 2007 104: 6800-6805; published online before print April 9 2007, 10.1073/pnas.0608885104 [Abstract] [Full Text] [Figures Only] [PDF]  

Microbiology

Daniel Grimm, Peter Staeheli, Martin Hufbauer, Iris Koerner, Luis Martínez-Sobrido, Alicia Solórzano, Adolfo García-Sastre, Otto Haller, and Georg Kochs
Replication fitness determines high virulence of influenza A virus in mice carrying functional Mx1 resistance gene
PNAS 2007 104: 6806-6811; published online before print April 10 2007, 10.1073/pnas.0701849104 [Abstract] [Full Text] [Figures Only] [PDF]  

Massimo Pizzato, Anna Helander, Elena Popova, Arianna Calistri, Alessia Zamborlini, Giorgio Palù, and Heinrich G. Göttlinger
Dynamin 2 is required for the enhancement of HIV-1 infectivity by Nef
PNAS 2007 104: 6812-6817; published online before print April 5 2007, 10.1073/pnas.0607622104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Neuroscience

Marcus A. Gray, Peter Taggart, Peter M. Sutton, David Groves, Diana R. Holdright, David Bradbury, David Brull, and Hugo D. Critchley
A cortical potential reflecting cardiac function
PNAS 2007 104: 6818-6823; published online before print April 9 2007, 10.1073/pnas.0609509104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Psyche H. Lee, Thongchai Sooksawate, Yuchio Yanagawa, Kaoru Isa, Tadashi Isa, and William C. Hall
Identity of a pathway for saccadic suppression
PNAS 2007 104: 6824-6827; published online before print April 9 2007, 10.1073/pnas.0701934104 [Abstract] [Full Text] [Figures Only] [PDF] OPEN ACCESS ARTICLE  

C. Alex Goddard, Daniel A. Butts, and Carla J. Shatz
Regulation of CNS synapses by neuronal MHC class I
PNAS 2007 104: 6828-6833; published online before print April 9 2007, 10.1073/pnas.0702023104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

XiaoChing Li, Xiu-Jie Wang, Jonathan Tannenhauser, Sheila Podell, Piali Mukherjee, Moritz Hertel, Jeremy Biane, Shoko Masuda, Fernando Nottebohm, and Terry Gaasterland
Genomic resources for songbird research and their use in characterizing gene expression during brain development
PNAS 2007 104: 6834-6839; published online before print April 10 2007, 10.1073/pnas.0701619104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE  

Marc Welter, Daniela Vallone, Tarek A. Samad, Hamid Meziane, Alessandro Usiello, and Emiliana Borrelli
Absence of dopamine D2 receptors unmasks an inhibitory control over the brain circuitries activated by cocaine
PNAS 2007 104: 6840-6845; published online before print April 10 2007, 10.1073/pnas.0610790104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

Pharmacology

Percy H. Carter, Rui-Qin Liu, William R. Foster, Joseph A. Tamasi, Andrew J. Tebben, Margaret Favata, Ada Staal, Mary Ellen Cvijic, Michele H. French, Vanessa Dell, Donald Apanovitch, Ming Lei, Qihong Zhao, Mark Cunningham, Carl P. Decicco, James M. Trzaskos, and Jean H. M. Feyen
Discovery of a small molecule antagonist of the parathyroid hormone receptor by using an N-terminal parathyroid hormone peptide probe
PNAS 2007 104: 6846-6851; published online before print April 11 2007, 10.1073/pnas.0605125104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Physiology

Huili Zheng, Clifford J. Stratton, Kazuto Morozumi, Jingling Jin, Ryuzo Yanagimachi, and Wei Yan
Lack of Spem1 causes aberrant cytoplasm removal, sperm deformation, and male infertility
PNAS 2007 104: 6852-6857; published online before print April 10 2007, 10.1073/pnas.0701669104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Robb Glenny, Susan Bernard, Blazej Neradilek, and Nayak Polissar
Quantifying the genetic influence on mammalian vascular tree structure
PNAS 2007 104: 6858-6863; published online before print April 9 2007, 10.1073/pnas.0610954104 [Abstract] [Full Text] [Figures Only] [PDF]  

Plant Biology

Maxim Golovkin, Sergei Spitsin, Vyacheslav Andrianov, Yuriy Smirnov, Yuhong Xiao, Natalia Pogrebnyak, Karen Markley, Robert Brodzik, Yuri Gleba, Stuart N. Isaacs, and Hilary Koprowski
Smallpox subunit vaccine produced in planta confers protection in mice
PNAS 2007 104: 6864-6869; published online before print April 11 2007, 10.1073/pnas.0701451104 [Abstract] [Full Text] [Figures Only] [PDF]  

up arrow CORRECTIONS

Correction for Narasimha Prasad et al., Characterization of capsaicin synthase and identification of its gene (csy1) for pungency factor capsaicin in pepper (Capsicum sp.) [Full Text] [PDF]  

Correction for Galvan et al., Reversal of Alzheimer's-like pathology and behavior in human APP transgenic mice by mutation of Asp664 [Full Text] [PDF]  

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