Find articles in this issue containing these words:

THIS WEEK IN PNAS

In This Issue
PNAS 2007 104: 7731-7732. [Full Text] [PDF]  

COMMENTARIES

Manuel Sanchez-Alavez and Tamas Bartfai

It all happens between Toll receptors and Caspase 1
PNAS 2007 104: 7733-7734; published online before print May 1 2007, 10.1073/pnas.0702505104 [Extract] [Full Text] [Figures Only] [PDF]  
See companion article on page 7205 in issue 17 of volume 104

Diego U. Ferreiro and Elizabeth A. Komives

The plastic landscape of repeat proteins
PNAS 2007 104: 7735-7736; published online before print May 3 2007, 10.1073/pnas.0702682104 [Extract] [Full Text] [Figures Only] [PDF]  
See companion article on page 7863

Anne-Marie Bleau and Eric C. Holland

Trapping the mouse genome to hunt human alterations
PNAS 2007 104: 7737-7738; published online before print May 3 2007, 10.1073/pnas.0702617104 [Extract] [Full Text] [Figures Only] [PDF]  
See companion article on page 8053

John Garthwaite

Neuronal nitric oxide synthase and the serotonin transporter get harmonious
PNAS 2007 104: 7739-7740; published online before print May 1 2007, 10.1073/pnas.0702508104 [Extract] [Full Text] [Figures Only] [PDF]  
See companion article on page 8119

PHYSICAL SCIENCES

Applied Mathematics

Kai Kadau, Charles Rosenblatt, John L. Barber, Timothy C. Germann, Zhibin Huang, Pierre Carlès, and Berni J. Alder

The importance of fluctuations in fluid mixing
PNAS 2007 104: 7741-7745; published online before print April 30 2007, 10.1073/pnas.0702871104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Applied Physical Sciences

Lazaros K. Gallos, Chaoming Song, Shlomo Havlin, and Hernán A. Makse

Scaling theory of transport in complex biological networks
PNAS 2007 104: 7746-7751; published online before print April 30 2007, 10.1073/pnas.0700250104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Rosamond L. Naylor, David S. Battisti, Daniel J. Vimont, Walter P. Falcon, and Marshall B. Burke

Assessing risks of climate variability and climate change for Indonesian rice agriculture
PNAS 2007 104: 7752-7757; published online before print May 2 2007, 10.1073/pnas.0701825104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

Chemistry

Shigeru Shimada, Yong-Hua Li, Yoong-Kee Choe, Masato Tanaka, Ming Bao, and Tadafumi Uchimaru

Multinuclear palladium compounds containing palladium centers ligated by five silicon atoms
PNAS 2007 104: 7758-7763; published online before print April 30 2007, 10.1073/pnas.0700450104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Luis Manuel Frutos, Tadeusz Andruniów, Fabrizio Santoro, Nicolas Ferré, and Massimo Olivucci

Tracking the excited-state time evolution of the visual pigment with multiconfigurational quantum chemistry
PNAS 2007 104: 7764-7769; published online before print April 30 2007, 10.1073/pnas.0701732104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Lisa Haines-Butterick, Karthikan Rajagopal, Monica Branco, Daphne Salick, Ronak Rughani, Matthew Pilarz, Matthew S. Lamm, Darrin J. Pochan, and Joel P. Schneider

Controlling hydrogelation kinetics by peptide design for three-dimensional encapsulation and injectable delivery of cells
PNAS 2007 104: 7791-7796; published online before print April 30 2007, 10.1073/pnas.0701980104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Appendix]  

Physics

M. G. L. van den Heuvel, M. P. de Graaff, S. G. Lemay, and C. Dekker

Electrophoresis of individual microtubules in microchannels
PNAS 2007 104: 7770-7775; published online before print April 30 2007, 10.1073/pnas.0608316104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Georgi I. Petrov, Rajan Arora, Vladislav V. Yakovlev, Xi Wang, Alexei V. Sokolov, and Marlan O. Scully

Comparison of coherent and spontaneous Raman microspectroscopies for noninvasive detection of single bacterial endospores
PNAS 2007 104: 7776-7779; published online before print May 1 2007, 10.1073/pnas.0702107104 [Abstract] [Full Text] [Figures Only] [PDF]  

SOCIAL SCIENCES

Psychology

Jonathan Winawer, Nathan Witthoft, Michael C. Frank, Lisa Wu, Alex R. Wade, and Lera Boroditsky

Russian blues reveal effects of language on color discrimination
PNAS 2007 104: 7780-7785; published online before print April 30 2007, 10.1073/pnas.0701644104 [Abstract] [Full Text] [Figures Only] [PDF]  

Social Sciences

Rosamond L. Naylor, David S. Battisti, Daniel J. Vimont, Walter P. Falcon, and Marshall B. Burke

Assessing risks of climate variability and climate change for Indonesian rice agriculture
PNAS 2007 104: 7752-7757; published online before print May 2 2007, 10.1073/pnas.0701825104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

Sustainability Science

Rosamond L. Naylor, David S. Battisti, Daniel J. Vimont, Walter P. Falcon, and Marshall B. Burke

Assessing risks of climate variability and climate change for Indonesian rice agriculture
PNAS 2007 104: 7752-7757; published online before print May 2 2007, 10.1073/pnas.0701825104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

BIOLOGICAL SCIENCES

Anthropology

Applied Biological Sciences

Lisa Haines-Butterick, Karthikan Rajagopal, Monica Branco, Daphne Salick, Ronak Rughani, Matthew Pilarz, Matthew S. Lamm, Darrin J. Pochan, and Joel P. Schneider

Controlling hydrogelation kinetics by peptide design for three-dimensional encapsulation and injectable delivery of cells
PNAS 2007 104: 7791-7796; published online before print April 30 2007, 10.1073/pnas.0701980104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Appendix]  

Jin Hwan Park, Kwang Ho Lee, Tae Yong Kim, and Sang Yup Lee Metabolic engineering of Escherichia coli for the production of L-valine based on transcriptome analysis and in silico gene knockout simulation PNAS 2007 104: 7797-7802; published online before print April 26 2007, 10.1073/pnas.0702609104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Biochemistry

Manuelle Quinaud, Sophie Plé, Viviana Job, Carlos Contreras-Martel, Jean-Pierre Simorre, Ina Attree, and Andréa Dessen

Structure of the heterotrimeric complex that regulates type III secretion needle formation
PNAS 2007 104: 7803-7808; published online before print April 30 2007, 10.1073/pnas.0610098104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Barbara Geering, Pedro R. Cutillas, Gemma Nock, Severine I. Gharbi, and Bart Vanhaesebroeck

Class IA phosphoinositide 3-kinases are obligate p85-p110 heterodimers
PNAS 2007 104: 7809-7814; published online before print April 30 2007, 10.1073/pnas.0700373104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Jae-hyeong Ko and Sidney Altman

OLE RNA, an RNA motif that is highly conserved in several extremophilic bacteria, is a substrate for and can be regulated by RNase P RNA
PNAS 2007 104: 7815-7820; published online before print April 30 2007, 10.1073/pnas.0701715104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Mary Anne T. Rubio, Irena Pastar, Kirk W. Gaston, Frank L. Ragone, Christian J. Janzen, George A. M. Cross, F. Nina Papavasiliou, and Juan D. Alfonzo

An adenosine-to-inosine tRNA-editing enzyme that can perform C-to-U deamination of DNA
PNAS 2007 104: 7821-7826; published online before print May 1 2007, 10.1073/pnas.0702394104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

Johannes Hutzler, Maria Schmid, Thomas Bernard, Bernard Henrissat, and Sabine Strahl

Membrane association is a determinant for substrate recognition by PMT4 protein O-mannosyltransferases
PNAS 2007 104: 7827-7832; published online before print April 30 2007, 10.1073/pnas.0700374104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Caroline A. Davis, Craig A. Bingman, Robert Landick, M. Thomas Record, Jr., and Ruth M. Saecker

Real-time footprinting of DNA in the first kinetically significant intermediate in open complex formation by Escherichia coli RNA polymerase
PNAS 2007 104: 7833-7838; published online before print April 30 2007, 10.1073/pnas.0609888104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Xiaoping Wang, Dagmar M. Truckses, Shinako Takada, Tatsushi Matsumura, Naoko Tanese, and Raymond H. Jacobson

Conserved region I of human coactivator TAF4 binds to a short hydrophobic motif present in transcriptional regulators
PNAS 2007 104: 7839-7844; published online before print May 1 2007, 10.1073/pnas.0608570104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Nisha Philip and Timothy A. Haystead

Characterization of a UBC13 kinase in Plasmodium falciparum
PNAS 2007 104: 7845-7850; published online before print April 23 2007, 10.1073/pnas.0611601104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

Chun J. Tsai, Sunny A. Kim, and Gilbert Chu Cernunnos/XLF promotes the ligation of mismatched and noncohesive DNA ends PNAS 2007 104: 7851-7856; published online before print April 30 2007, 10.1073/pnas.0702620104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Sergey V. Novoselov, Alexey V. Lobanov, Deame Hua, Marina V. Kasaikina, Dolph L. Hatfield, and Vadim N. Gladyshev

A highly efficient form of the selenocysteine insertion sequence element in protozoan parasites and its use in mammalian cells
PNAS 2007 104: 7857-7862; published online before print April 30 2007, 10.1073/pnas.0610683104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Biophysics

Luis Manuel Frutos, Tadeusz Andruniów, Fabrizio Santoro, Nicolas Ferré, and Massimo Olivucci

Tracking the excited-state time evolution of the visual pigment with multiconfigurational quantum chemistry
PNAS 2007 104: 7764-7769; published online before print April 30 2007, 10.1073/pnas.0701732104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

M. G. L. van den Heuvel, M. P. de Graaff, S. G. Lemay, and C. Dekker

Electrophoresis of individual microtubules in microchannels
PNAS 2007 104: 7770-7775; published online before print April 30 2007, 10.1073/pnas.0608316104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Georgi I. Petrov, Rajan Arora, Vladislav V. Yakovlev, Xi Wang, Alexei V. Sokolov, and Marlan O. Scully

Comparison of coherent and spontaneous Raman microspectroscopies for noninvasive detection of single bacterial endospores
PNAS 2007 104: 7776-7779; published online before print May 1 2007, 10.1073/pnas.0702107104 [Abstract] [Full Text] [Figures Only] [PDF]  

Nicolas D. Werbeck and Laura S. Itzhaki From the Cover: Probing a moving target with a plastic unfolding intermediate of an ankyrin-repeat protein PNAS 2007 104: 7863-7868; published online before print May 2 2007, 10.1073/pnas.0610315104 [Abstract] [Full Text] [Figures Only] [PDF]   See Commentary on page 7735

Billy K. Poon, Xiaorui Chen, Mingyang Lu, Nand K. Vyas, Florante A. Quiocho, Qinghua Wang, and Jianpeng Ma

Normal mode refinement of anisotropic thermal parameters for a supramolecular complex at 3.42-Å crystallographic resolution
PNAS 2007 104: 7869-7874; published online before print April 30 2007, 10.1073/pnas.0701204104 [Abstract] [Full Text] [Figures Only] [PDF]  

Chaohong Sun, Danying Song, Rachel A. Davis-Taber, Leo W. Barrett, Victoria E. Scott, Paul L. Richardson, Ana Pereda-Lopez, Marie E. Uchic, Larry R. Solomon, Marc R. Lake, Karl A. Walter, Philip J. Hajduk, and Edward T. Olejniczak

Solution structure and mutational analysis of pituitary adenylate cyclase-activating polypeptide binding to the extracellular domain of PAC1-R_S
PNAS 2007 104: 7875-7880; published online before print April 30 2007, 10.1073/pnas.0611397104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Kazumasa Muramoto, Kunio Hirata, Kyoko Shinzawa-Itoh, Shinji Yoko-o, Eiki Yamashita, Hiroshi Aoyama, Tomitake Tsukihara, and Shinya Yoshikawa

A histidine residue acting as a controlling site for dioxygen reduction and proton pumping by cytochrome c oxidase
PNAS 2007 104: 7881-7886; published online before print April 30 2007, 10.1073/pnas.0610031104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Jonathan L. Cape, Michael K. Bowman, and David M. Kramer

A semiquinone intermediate generated at the Q_o site of the cytochrome bc₁ complex: Importance for the Q-cycle and superoxide production
PNAS 2007 104: 7887-7892; published online before print April 30 2007, 10.1073/pnas.0702621104 [Abstract] [Full Text] [Figures Only] [PDF]  

Oleg A. Andreev, Allison D. Dupuy, Michael Segala, Srikanth Sandugu, David A. Serra, Clinton O. Chichester, Donald M. Engelman, and Yana K. Reshetnyak Mechanism and uses of a membrane peptide that targets tumors and other acidic tissues in vivo PNAS 2007 104: 7893-7898; published online before print May 1 2007, 10.1073/pnas.0702439104 [Abstract] [Full Text] [Figures Only] [PDF] OPEN ACCESS ARTICLE

S. W. Schneider, S. Nuschele, A. Wixforth, C. Gorzelanny, A. Alexander-Katz, R. R. Netz, and M. F. Schneider

Shear-induced unfolding triggers adhesion of von Willebrand factor fibers
PNAS 2007 104: 7899-7903; published online before print April 30 2007, 10.1073/pnas.0608422104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Fabiana V. Campos, Baron Chanda, Benoît Roux, and Francisco Bezanilla

Two atomic constraints unambiguously position the S4 segment relative to S1 and S2 segments in the closed state of Shaker K channel
PNAS 2007 104: 7904-7909; published online before print April 30 2007, 10.1073/pnas.0702638104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

J. K. Amisha Kamal, Sabrina A. Benchaar, Keiji Takamoto, Emil Reisler, and Mark R. Chance

Three-dimensional structure of cofilin bound to monomeric actin derived by structural mass spectrometry data
PNAS 2007 104: 7910-7915; published online before print April 30 2007, 10.1073/pnas.0611283104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Text]  

Kirstin A. Walther, Frauke Gräter, Lorna Dougan, Carmen L. Badilla, Bruce J. Berne, and Julio M. Fernandez

Signatures of hydrophobic collapse in extended proteins captured with force spectroscopy
PNAS 2007 104: 7916-7921; published online before print April 30 2007, 10.1073/pnas.0702179104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

A. V. Panfilov, R. H. Keldermann, and M. P. Nash

Drift and breakup of spiral waves in reaction–diffusion–mechanics systems
PNAS 2007 104: 7922-7926; published online before print April 27 2007, 10.1073/pnas.0701895104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

William M. Oldham, Ned Van Eps, Anita M. Preininger, Wayne L. Hubbell, and Heidi E. Hamm

Mapping allosteric connections from the receptor to the nucleotide-binding pocket of heterotrimeric G proteins
PNAS 2007 104: 7927-7932; published online before print April 26 2007, 10.1073/pnas.0702623104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

Cell Biology

Lindsay M. Rohas, Julie St-Pierre, Marc Uldry, Sibylle Jäger, Christoph Handschin, and Bruce M. Spiegelman

A fundamental system of cellular energy homeostasis regulated by PGC-1
PNAS 2007 104: 7933-7938; published online before print April 30 2007, 10.1073/pnas.0702683104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Emmanuel Boucrot and Tomas Kirchhausen

Endosomal recycling controls plasma membrane area during mitosis
PNAS 2007 104: 7939-7944; published online before print May 1 2007, 10.1073/pnas.0702511104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Eniko Nagy, Zsolt Balogi, Imre Gombos, Malin Åkerfelt, Anders Björkbom, Gábor Balogh, Zsolt Török, Andriy Maslyanko, Anna Fiszer-Kierzkowska, Katarzyna Lisowska, Peter J. Slotte, Lea Sistonen, Ibolya Horváth, and László Vígh

Hyperfluidization-coupled membrane microdomain reorganization is linked to activation of the heat shock response in a murine melanoma cell line
PNAS 2007 104: 7945-7950; published online before print April 30 2007, 10.1073/pnas.0702557104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Li Li, Binwei Deng, Guichun Xing, Yan Teng, Chunyan Tian, Xuan Cheng, Xiushan Yin, Juntao Yang, Xue Gao, Yunping Zhu, Qihong Sun, Lingqiang Zhang, Xiao Yang, and Fuchu He

PACT is a negative regulator of p53 and essential for cell growth and embryonic development
PNAS 2007 104: 7951-7956; published online before print April 30 2007, 10.1073/pnas.0701916104 [Abstract] [Full Text] [Figures Only] [PDF]  

Pietro Laneve, Lucia Di Marcotullio, Ubaldo Gioia, Micol E. Fiori, Elisabetta Ferretti, Alberto Gulino, Irene Bozzoni, and Elisa Caffarelli

The interplay between microRNAs and the neurotrophin receptor tropomyosin-related kinase C controls proliferation of human neuroblastoma cells
PNAS 2007 104: 7957-7962; published online before print May 1 2007, 10.1073/pnas.0700071104 [Abstract] [Full Text] [Figures Only] [PDF]  

Developmental Biology

Cristina Molnar, Helena Holguin, Federico Mayor, Jr., Ana Ruiz-Gomez, and Jose F. de Celis

The G protein-coupled receptor regulatory kinase GPRK2 participates in Hedgehog signaling in Drosophila
PNAS 2007 104: 7963-7968; published online before print May 1 2007, 10.1073/pnas.0702374104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figure]  

Poorna Viswanathan, Toshiyuki Ueki, Sumiko Inouye, and Lee Kroos

Combinatorial regulation of genes essential for Myxococcus xanthus development involves a response regulator and a LysR-type regulator
PNAS 2007 104: 7969-7974; published online before print April 30 2007, 10.1073/pnas.0701569104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Mei Xin, Eric M. Small, Eva van Rooij, Xiaoxia Qi, James A. Richardson, Deepak Srivastava, Osamu Nakagawa, and Eric N. Olson

Essential roles of the bHLH transcription factor Hrt2 in repression of atrial gene expression and maintenance of postnatal cardiac function
PNAS 2007 104: 7975-7980; published online before print April 27 2007, 10.1073/pnas.0702447104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Evolution

Nam-Hyuk Cho, Hang-Rae Kim, Jung-Hee Lee, Se-Yoon Kim, Jaejong Kim, Sunho Cha, Sang-Yoon Kim, Alistair C. Darby, Hans-Henrik Fuxelius, Jun Yin, Ju Han Kim, Jihun Kim, Sang Joo Lee, Young-Sang Koh, Won-Jong Jang, Kyung-Hee Park, Siv G. E. Andersson, Myung-Sik Choi, and Ik-Sang Kim

The Orientia tsutsugamushi genome reveals massive proliferation of conjugative type IV secretion system and host–cell interaction genes
PNAS 2007 104: 7981-7986; published online before print May 2 2007, 10.1073/pnas.0611553104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Zeinab Annan, Patrick Durand, Francisco J. Ayala, Céline Arnathau, Parfait Awono-Ambene, Frédéric Simard, Fabien G. Razakandrainibe, Jacob C. Koella, Didier Fontenille, and François Renaud

Population genetic structure of Plasmodium falciparum in the two main African vectors, Anopheles gambiae and Anopheles funestus
PNAS 2007 104: 7987-7992; published online before print April 30 2007, 10.1073/pnas.0702715104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Tables]  

Roman Biek, J. Caroline Henderson, Lance A. Waller, Charles E. Rupprecht, and Leslie A. Real

A high-resolution genetic signature of demographic and spatial expansion in epizootic rabies virus
PNAS 2007 104: 7993-7998; published online before print April 30 2007, 10.1073/pnas.0700741104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Luke Hakes, Simon C. Lovell, Stephen G. Oliver, and David L. Robertson

Specificity in protein interactions and its relationship with sequence diversity and coevolution
PNAS 2007 104: 7999-8004; published online before print April 27 2007, 10.1073/pnas.0609962104 [Abstract] [Full Text] [Figures Only] [PDF]  

Craig B. Lowe, Gill Bejerano, and David Haussler

Thousands of human mobile element fragments undergo strong purifying selection near developmental genes
PNAS 2007 104: 8005-8010; published online before print April 26 2007, 10.1073/pnas.0611223104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Genetics

Cinzia Sevignani, George A. Calin, Stephanie C. Nnadi, Masayoshi Shimizu, Ramana V. Davuluri, Terry Hyslop, Peter Demant, Carlo M. Croce, and Linda D. Siracusa

MicroRNA genes are frequently located near mouse cancer susceptibility loci
PNAS 2007 104: 8017-8022; published online before print April 30 2007, 10.1073/pnas.0702177104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Yi Huang, Eriko Greene, Tracy Murray Stewart, Andrew C. Goodwin, Stephen B. Baylin, Patrick M. Woster, and Robert A. Casero, Jr Inhibition of lysine-specific demethylase 1 by polyamine analogues results in reexpression of aberrantly silenced genes PNAS 2007 104: 8023-8028; published online before print April 26 2007, 10.1073/pnas.0700720104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Immunology

Simone A. Joosten, Krista E. van Meijgaarden, Nigel D. L. Savage, Tjitske de Boer, Frédéric Triebel, Annemieke van der Wal, Emile de Heer, Michèl R. Klein, Annemieke Geluk, and Tom H. M. Ottenhoff

Identification of a human CD8⁺ regulatory T cell subset that mediates suppression through the chemokine CC chemokine ligand 4
PNAS 2007 104: 8029-8034; published online before print May 2 2007, 10.1073/pnas.0702257104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

Becca Asquith, Yan Zhang, Angelina J. Mosley, Catherine M. de Lara, Diana L. Wallace, Andrew Worth, Lambrini Kaftantzi, Kiran Meekings, George E. Griffin, Yuetsu Tanaka, David F. Tough, Peter C. Beverley, Graham P. Taylor, Derek C. Macallan, and Charles R. M. Bangham In vivo T lymphocyte dynamics in humans and the impact of human T-lymphotropic virus 1 infection PNAS 2007 104: 8035-8040; published online before print May 1 2007, 10.1073/pnas.0608832104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Joseph A. Duncan, Daniel T. Bergstralh, Yanhong Wang, Stephen B. Willingham, Zhengmao Ye, Albert G. Zimmermann, and Jenny Pan-Yun Ting

Cryopyrin/NALP3 binds ATP/dATP, is an ATPase, and requires ATP binding to mediate inflammatory signaling
PNAS 2007 104: 8041-8046; published online before print May 2 2007, 10.1073/pnas.0611496104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Uzma A. Hasan, Christophe Caux, Ivan Perrot, Anne-Claire Doffin, Christine Menetrier-Caux, Giorgio Trinchieri, Massimo Tommasino, and Jaromir Vlach

Cell proliferation and survival induced by Toll-like receptors is antagonized by type I IFNs
PNAS 2007 104: 8047-8052; published online before print April 26 2007, 10.1073/pnas.0700664104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

Medical Sciences

Herman J. Ng, Edward R. Whittemore, Minhtam B. Tran, Derk J. Hogenkamp, Ron S. Broide, Timothy B. Johnstone, Lijun Zheng, Karen E. Stevens, and Kelvin W. Gee

Nootropic 7 nicotinic receptor allosteric modulator derived from GABA_A receptor modulators
PNAS 2007 104: 8059-8064; published online before print April 30 2007, 10.1073/pnas.0701321104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

David F. Moore, Monique P. Gelderman, Paulo A. Ferreira, Steven R. Fuhrmann, Haiqing Yi, Abdel Elkahloun, Lisa M. Lix, Roscoe O. Brady, Raphael Schiffmann, and Ehud Goldin Genomic abnormalities of the murine model of Fabry disease after disease-related perturbation, a systems biology approach PNAS 2007 104: 8065-8070; published online before print April 30 2007, 10.1073/pnas.0701991104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

R. K. Lindemann, A. Newbold, K. F. Whitecross, L. A. Cluse, A. J. Frew, L. Ellis, S. Williams, A. P. Wiegmans, A. E. Dear, C. L. Scott, M. Pellegrini, A. Wei, V. M. Richon, Paul A. Marks, S. W. Lowe, M. J. Smyth, and R. W. Johnstone

Analysis of the apoptotic and therapeutic activities of histone deacetylase inhibitors by using a mouse model of B cell lymphoma
PNAS 2007 104: 8071-8076; published online before print April 30 2007, 10.1073/pnas.0702294104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

James D. Chang, Galina K. Sukhova, Peter Libby, Eugenia Schvartz, Alice H. Lichtenstein, Seth J. Field, Caitlin Kennedy, Swetha Madhavarapu, Ji Luo, Dianqing Wu, and Lewis C. Cantley Deletion of the phosphoinositide 3-kinase p110 gene attenuates murine atherosclerosis PNAS 2007 104: 8077-8082; published online before print May 2 2007, 10.1073/pnas.0702663104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Yanmei Li, Lihua Wang, Shunlin Li, Xiaoying Chen, Yuemao Shen, Zhongkai Zhang, Hongping He, Wenbo Xu, Yuelong Shu, Guodong Liang, Rongxiang Fang, and Xiaojiang Hao

Seco-pregnane steroids target the subgenomic RNA of alphavirus-like RNA viruses
PNAS 2007 104: 8083-8088; published online before print April 30 2007, 10.1073/pnas.0702398104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Microbiology

Silke Busch, Elke U. Schwier, Krystyna Nahlik, Özür Bayram, Kerstin Helmstaedt, Oliver W. Draht, Sven Krappmann, Oliver Valerius, William N. Lipscomb, and Gerhard H. Braus

An eight-subunit COP9 signalosome with an intact JAMM motif is required for fungal fruit body formation
PNAS 2007 104: 8089-8094; published online before print April 30 2007, 10.1073/pnas.0702108104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Tables]  

Katrina A. Lythgoe, Liam J. Morrison, Andrew F. Read, and J. David Barry

Parasite-intrinsic factors can explain ordered progression of trypanosome antigenic variation
PNAS 2007 104: 8095-8100; published online before print April 26 2007, 10.1073/pnas.0606206104 [Abstract] [Full Text] [Figures Only] [PDF]  

Lutz Wiehlmann, Gerd Wagner, Nina Cramer, Benny Siebert, Peter Gudowius, Gracia Morales, Thilo Köhler, Christian van Delden, Christian Weinel, Peter Slickers, and Burkhard Tümmler

Population structure of Pseudomonas aeruginosa
PNAS 2007 104: 8101-8106; published online before print April 27 2007, 10.1073/pnas.0609213104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Dongru Qiu, Vonya M. Eisinger, Donald W. Rowen, and Hongwei D. Yu

Regulated proteolysis controls mucoid conversion in Pseudomonas aeruginosa
PNAS 2007 104: 8107-8112; published online before print April 30 2007, 10.1073/pnas.0702660104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Kelly C. Rice, Ethan E. Mann, Jennifer L. Endres, Elizabeth C. Weiss, James E. Cassat, Mark S. Smeltzer, and Kenneth W. Bayles

The cidA murein hydrolase regulator contributes to DNA release and biofilm development in Staphylococcus aureus
PNAS 2007 104: 8113-8118; published online before print April 23 2007, 10.1073/pnas.0610226104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Neuroscience

Juliana Yacubian, Tobias Sommer, Katrin Schroeder, Jan Gläscher, Raffael Kalisch, Boris Leuenberger, Dieter F. Braus, and Christian Büchel Gene–gene interaction associated with neural reward sensitivity PNAS 2007 104: 8125-8130; published online before print May 2 2007, 10.1073/pnas.0702029104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Kristine Roy, Joshua C. Murtie, Bassem F. El-Khodor, Nicole Edgar, S. Pablo Sardi, Bryan M. Hooks, Marianne Benoit-Marand, Chinfei Chen, Holly Moore, Patricio O'Donnell, Daniela Brunner, and Gabriel Corfas

Loss of erbB signaling in oligodendrocytes alters myelin and dopaminergic function, a potential mechanism for neuropsychiatric disorders
PNAS 2007 104: 8131-8136; published online before print May 1 2007, 10.1073/pnas.0702157104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Xintian Hu, Huihui Jiang, Chaoliang Gu, Chuanyu Li, and David L. Sparks

Reliability of oculomotor command signals carried by individual neurons
PNAS 2007 104: 8137-8142; published online before print April 30 2007, 10.1073/pnas.0702799104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figure]  

H. Wang, J. Peca, M. Matsuzaki, K. Matsuzaki, J. Noguchi, L. Qiu, D. Wang, F. Zhang, E. Boyden, K. Deisseroth, H. Kasai, W. C. Hall, G. Feng, and G. J. Augustine

High-speed mapping of synaptic connectivity using photostimulation in Channelrhodopsin-2 transgenic mice
PNAS 2007 104: 8143-8148; published online before print May 1 2007, 10.1073/pnas.0700384104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Caroline Geisler, David Robbe, Michaël Zugaro, Anton Sirota, and György Buzsáki

Hippocampal place cell assemblies are speed-controlled oscillators
PNAS 2007 104: 8149-8154; published online before print April 30 2007, 10.1073/pnas.0610121104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Morgane Besson, Sylvie Granon, Monica Mameli-Engvall, Isabelle Cloëz-Tayarani, Nicolas Maubourguet, Anne Cormier, Pierre Cazala, Vincent David, Jean-Pierre Changeux, and Philippe Faure Long-term effects of chronic nicotine exposure on brain nicotinic receptors PNAS 2007 104: 8155-8160; published online before print April 30 2007, 10.1073/pnas.0702698104 [Abstract] [Full Text] [Figures Only