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THIS WEEK IN PNAS

In This Issue
PNAS 2007 104: 9101-9102. [Full Text] [PDF]  

COMMENTARIES

Fred C. Dobbs

Après le déluge: Microbial landscape of New Orleans after the hurricanes
PNAS 2007 104: 9103-9104; published online before print May 22 2007, 10.1073/pnas.0703191104 [Extract] [Full Text] [PDF]  
See companion article on page 9029 in issue 21 of volume 104

Eugene V. Koonin

An RNA-making reactor for the origin of life
PNAS 2007 104: 9105-9106; published online before print May 22 2007, 10.1073/pnas.0702699104 [Extract] [Full Text] [Figures Only] [PDF]  
See companion article on page 9346

M. Joan Curcio and Marlene Belfort

The beginning of the end: Links between ancient retroelements and modern telomerases
PNAS 2007 104: 9107-9108; published online before print May 21 2007, 10.1073/pnas.0703224104 [Extract] [Full Text] [Figures Only] [PDF]  
See companion article on page 9352

James J. Giovannoni

Completing a pathway to plant vitamin C synthesis
PNAS 2007 104: 9109-9110; published online before print May 21 2007, 10.1073/pnas.0703222104 [Extract] [Full Text] [Figures Only] [PDF]  
See companion article on page 9534

SPECIAL FEATURE

Introductory Perspectives

Ho-kwang Mao and Russell J. Hemley

High-Pressure Geoscience Special Feature: The high-pressure dimension in earth and planetary science
PNAS 2007 104: 9114-9115; published online before print May 22 2007, 10.1073/pnas.0703653104 [Extract] [Full Text] [Figures Only] [PDF]  

Perspectives

J. G. Liou, R. Y. Zhang, and W. G. Ernst

High-Pressure Geoscience Special Feature: Very high-pressure orogenic garnet peridotites
PNAS 2007 104: 9116-9121; published online before print May 22 2007, 10.1073/pnas.0607300104 [Abstract] [Full Text] [Figures Only] [PDF]  

Research Articles

Yuri N. Palyanov, Vladislav S. Shatsky, Nikolay V. Sobolev, and Alexander G. Sokol

High-Pressure Geoscience Special Feature: The role of mantle ultrapotassic fluids in diamond formation
PNAS 2007 104: 9122-9127; published online before print March 22 2007, 10.1073/pnas.0608134104 [Abstract] [Full Text] [Figures Only] [PDF]  

Larissa F. Dobrzhinetskaya, Richard Wirth, and Harry W. Green, II

From the Cover: High-Pressure Geoscience Special Feature: A look inside of diamond-forming media in deep subduction zones
PNAS 2007 104: 9128-9132; published online before print March 26 2007, 10.1073/pnas.0609161104 [Abstract] [Full Text] [Figures Only] [PDF]  

Harry W. Green, II

High-Pressure Geoscience Special Feature: Shearing instabilities accompanying high-pressure phase transformations and the mechanics of deep earthquakes
PNAS 2007 104: 9133-9138; published online before print April 27 2007, 10.1073/pnas.0608045104 [Abstract] [Full Text] [Figures Only] [PDF]  

Fabio Cammarano and Barbara Romanowicz

High-Pressure Geoscience Special Feature: Insights into the nature of the transition zone from physically constrained inversion of long-period seismic data
PNAS 2007 104: 9139-9144; published online before print May 2 2007, 10.1073/pnas.0608075104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

Baosheng Li and Robert C. Liebermann

High-Pressure Geoscience Special Feature: Indoor seismology by probing the Earth's interior by using sound velocity measurements at high pressures and temperatures
PNAS 2007 104: 9145-9150; published online before print May 7 2007, 10.1073/pnas.0608609104 [Abstract] [Full Text] [Figures Only] [PDF]  

Daoyuan Sun, Eh Tan, Don Helmberger, and Michael Gurnis

High-Pressure Geoscience Special Feature: Seismological support for the metastable superplume model, sharp features, and phase changes within the lower mantle
PNAS 2007 104: 9151-9155; published online before print April 10 2007, 10.1073/pnas.0608160104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Marc Monnereau and David A. Yuen

High-Pressure Geoscience Special Feature: Topology of the postperovskite phase transition and mantle dynamics
PNAS 2007 104: 9156-9161; published online before print May 3 2007, 10.1073/pnas.0608480104 [Abstract] [Full Text] [Figures Only] [PDF]  

Bin Chen, Lili Gao, Ken-ichi Funakoshi, and Jie Li

High-Pressure Geoscience Special Feature: Thermal expansion of iron-rich alloys and implications for the Earth's core
PNAS 2007 104: 9162-9167; published online before print April 19 2007, 10.1073/pnas.0610474104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Eyvaz I. Isaev, Natalia V. Skorodumova, Rajeev Ahuja, Yuri K. Vekilov, and Börje Johansson

High-Pressure Geoscience Special Feature: Dynamical stability of Fe-H in the Earth's mantle and core regions
PNAS 2007 104: 9168-9171; published online before print May 4 2007, 10.1073/pnas.0609701104 [Abstract] [Full Text] [Figures Only] [PDF]  

Raymond Jeanloz, Peter M. Celliers, Gilbert W. Collins, Jon H. Eggert, Kanani K. M. Lee, R. Stewart McWilliams, Stéphanie Brygoo, and Paul Loubeyre

High-Pressure Geoscience Special Feature: Achieving high-density states through shock-wave loading of precompressed samples
PNAS 2007 104: 9172-9177; published online before print May 9 2007, 10.1073/pnas.0608170104 [Abstract] [Full Text] [Figures Only] [PDF]  

Geun Woo Lee, William J. Evans, and Choong-Shik Yoo

High-Pressure Geoscience Special Feature: Dynamic pressure-induced dendritic and shock crystal growth of ice VI
PNAS 2007 104: 9178-9181; published online before print February 12 2007, 10.1073/pnas.0609390104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Movie]  

Yingwei Fei, Angele Ricolleau, Mark Frank, Kenji Mibe, Guoyin Shen, and Vitali Prakapenka

High-Pressure Geoscience Special Feature: Toward an internally consistent pressure scale
PNAS 2007 104: 9182-9186; published online before print May 2 2007, 10.1073/pnas.0609013104 [Abstract] [Full Text] [Figures Only] [PDF]  

Alexandra Navrotsky, Maria Dorogova, Frances Hellman, David W. Cooke, Barry L. Zink, Charles E. Lesher, Juliana Boerio-Goates, Brian F. Woodfield, and Brian Lang

High-Pressure Geoscience Special Feature: Application of calorimetry on a chip to high-pressure materials
PNAS 2007 104: 9187-9191; published online before print May 8 2007, 10.1073/pnas.0608165104 [Abstract] [Full Text] [Figures Only] [PDF]  

Anne M. Hofmeister

High-Pressure Geoscience Special Feature: Pressure dependence of thermal transport properties
PNAS 2007 104: 9192-9197; published online before print February 13 2007, 10.1073/pnas.0610734104 [Abstract] [Full Text] [Figures Only] [PDF]  

PROFILES

H. Davis Tinsley

Profile of Daniel L. Hartl
PNAS 2007 104: 9111-9113; published online before print May 22 2007, 10.1073/pnas.0703562104 [Extract] [Full Text] [Figures Only] [PDF]  

PHYSICAL SCIENCES

Applied Mathematics

Shannon C. Wieland, John S. Brownstein, Bonnie Berger, and Kenneth D. Mandl

Density-equalizing Euclidean minimum spanning trees for the detection of all disease cluster shapes
PNAS 2007 104: 9404-9409; published online before print May 22 2007, 10.1073/pnas.0609457104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Applied Physical Sciences

Chemistry

Elena Stolyarova, Kwang Taeg Rim, Sunmin Ryu, Janina Maultzsch, Philip Kim, Louis E. Brus, Tony F. Heinz, Mark S. Hybertsen, and George W. Flynn High-resolution scanning tunneling microscopy imaging of mesoscopic graphene sheets on an insulating surface PNAS 2007 104: 9209-9212; published online before print May 21 2007, 10.1073/pnas.0703337104 [Abstract] [Full Text] [Figures Only] [PDF] OPEN ACCESS ARTICLE

Engineering

Geology

Yuri N. Palyanov, Vladislav S. Shatsky, Nikolay V. Sobolev, and Alexander G. Sokol

High-Pressure Geoscience Special Feature: The role of mantle ultrapotassic fluids in diamond formation
PNAS 2007 104: 9122-9127; published online before print March 22 2007, 10.1073/pnas.0608134104 [Abstract] [Full Text] [Figures Only] [PDF]  

Larissa F. Dobrzhinetskaya, Richard Wirth, and Harry W. Green, II

From the Cover: High-Pressure Geoscience Special Feature: A look inside of diamond-forming media in deep subduction zones
PNAS 2007 104: 9128-9132; published online before print March 26 2007, 10.1073/pnas.0609161104 [Abstract] [Full Text] [Figures Only] [PDF]  

Nick Marriner, Christophe Morhange, and Samuel Meulé

Holocene morphogenesis of Alexander the Great's isthmus at Tyre in Lebanon
PNAS 2007 104: 9218-9223; published online before print May 18 2007, 10.1073/pnas.0611325104 [Abstract] [Full Text] [Figures Only] [PDF]  

Philipp Baaske, Franz M. Weinert, Stefan Duhr, Kono H. Lemke, Michael J. Russell, and Dieter Braun From the Cover: Extreme accumulation of nucleotides in simulated hydrothermal pore systems PNAS 2007 104: 9346-9351; published online before print May 9 2007, 10.1073/pnas.0609592104 [Abstract] [Full Text] [Figures Only] [PDF]   See Commentary on page 9105

Geophysics

Harry W. Green, II

High-Pressure Geoscience Special Feature: Shearing instabilities accompanying high-pressure phase transformations and the mechanics of deep earthquakes
PNAS 2007 104: 9133-9138; published online before print April 27 2007, 10.1073/pnas.0608045104 [Abstract] [Full Text] [Figures Only] [PDF]  

Fabio Cammarano and Barbara Romanowicz

High-Pressure Geoscience Special Feature: Insights into the nature of the transition zone from physically constrained inversion of long-period seismic data
PNAS 2007 104: 9139-9144; published online before print May 2 2007, 10.1073/pnas.0608075104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

Baosheng Li and Robert C. Liebermann

High-Pressure Geoscience Special Feature: Indoor seismology by probing the Earth's interior by using sound velocity measurements at high pressures and temperatures
PNAS 2007 104: 9145-9150; published online before print May 7 2007, 10.1073/pnas.0608609104 [Abstract] [Full Text] [Figures Only] [PDF]  

Daoyuan Sun, Eh Tan, Don Helmberger, and Michael Gurnis

High-Pressure Geoscience Special Feature: Seismological support for the metastable superplume model, sharp features, and phase changes within the lower mantle
PNAS 2007 104: 9151-9155; published online before print April 10 2007, 10.1073/pnas.0608160104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Marc Monnereau and David A. Yuen

High-Pressure Geoscience Special Feature: Topology of the postperovskite phase transition and mantle dynamics
PNAS 2007 104: 9156-9161; published online before print May 3 2007, 10.1073/pnas.0608480104 [Abstract] [Full Text] [Figures Only] [PDF]  

Bin Chen, Lili Gao, Ken-ichi Funakoshi, and Jie Li

High-Pressure Geoscience Special Feature: Thermal expansion of iron-rich alloys and implications for the Earth's core
PNAS 2007 104: 9162-9167; published online before print April 19 2007, 10.1073/pnas.0610474104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Eyvaz I. Isaev, Natalia V. Skorodumova, Rajeev Ahuja, Yuri K. Vekilov, and Börje Johansson

High-Pressure Geoscience Special Feature: Dynamical stability of Fe-H in the Earth's mantle and core regions
PNAS 2007 104: 9168-9171; published online before print May 4 2007, 10.1073/pnas.0609701104 [Abstract] [Full Text] [Figures Only] [PDF]  

Geun Woo Lee, William J. Evans, and Choong-Shik Yoo

High-Pressure Geoscience Special Feature: Dynamic pressure-induced dendritic and shock crystal growth of ice VI
PNAS 2007 104: 9178-9181; published online before print February 12 2007, 10.1073/pnas.0609390104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Movie]  

Yingwei Fei, Angele Ricolleau, Mark Frank, Kenji Mibe, Guoyin Shen, and Vitali Prakapenka

High-Pressure Geoscience Special Feature: Toward an internally consistent pressure scale
PNAS 2007 104: 9182-9186; published online before print May 2 2007, 10.1073/pnas.0609013104 [Abstract] [Full Text] [Figures Only] [PDF]  

Alexandra Navrotsky, Maria Dorogova, Frances Hellman, David W. Cooke, Barry L. Zink, Charles E. Lesher, Juliana Boerio-Goates, Brian F. Woodfield, and Brian Lang

High-Pressure Geoscience Special Feature: Application of calorimetry on a chip to high-pressure materials
PNAS 2007 104: 9187-9191; published online before print May 8 2007, 10.1073/pnas.0608165104 [Abstract] [Full Text] [Figures Only] [PDF]  

Anne M. Hofmeister

High-Pressure Geoscience Special Feature: Pressure dependence of thermal transport properties
PNAS 2007 104: 9192-9197; published online before print February 13 2007, 10.1073/pnas.0610734104 [Abstract] [Full Text] [Figures Only] [PDF]  

Physics

Raymond Jeanloz, Peter M. Celliers, Gilbert W. Collins, Jon H. Eggert, Kanani K. M. Lee, R. Stewart McWilliams, Stéphanie Brygoo, and Paul Loubeyre

High-Pressure Geoscience Special Feature: Achieving high-density states through shock-wave loading of precompressed samples
PNAS 2007 104: 9172-9177; published online before print May 9 2007, 10.1073/pnas.0608170104 [Abstract] [Full Text] [Figures Only] [PDF]  

Erel Levine and Terence Hwa

Stochastic fluctuations in metabolic pathways
PNAS 2007 104: 9224-9229; published online before print May 18 2007, 10.1073/pnas.0610987104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

David L. Bostick and Charles L. Brooks, III

Selectivity in K⁺ channels is due to topological control of the permeant ion's coordinated state
PNAS 2007 104: 9260-9265; published online before print May 22 2007, 10.1073/pnas.0700554104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

SOCIAL SCIENCES

Anthropology

Nick Marriner, Christophe Morhange, and Samuel Meulé

Holocene morphogenesis of Alexander the Great's isthmus at Tyre in Lebanon
PNAS 2007 104: 9218-9223; published online before print May 18 2007, 10.1073/pnas.0611325104 [Abstract] [Full Text] [Figures Only] [PDF]  

Economic Sciences

BIOLOGICAL SCIENCES

Biochemistry

Seung-Wook Chi, Cheol-Young Maeng, Seung Jun Kim, Mee Sook Oh, Chun Jeih Ryu, Sang Jick Kim, Kyou-Hoon Han, Hyo Jeong Hong, and Seong Eon Ryu

Broadly neutralizing anti-hepatitis B virus antibody reveals a complementarity determining region H3 lid-opening mechanism
PNAS 2007 104: 9230-9235; published online before print May 17 2007, 10.1073/pnas.0701279104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Eunha Hwang, Kyoung-Seok Ryu, Kimmo Pääkkönen, Peter Güntert, Hae-Kap Cheong, Dae-Sik Lim, Jie-Oh Lee, Young Ho Jeon, and Chaejoon Cheong

Structural insight into dimeric interaction of the SARAH domains from Mst1 and RASSF family proteins in the apoptosis pathway
PNAS 2007 104: 9236-9241; published online before print May 21 2007, 10.1073/pnas.0610716104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Kelvin Y. Kwan, Rebecca J. Greenwald, Subhasis Mohanty, Arlene H. Sharpe, Albert C. Shaw, and James C. Wang

Development of autoimmunity in mice lacking DNA topoisomerase 3
PNAS 2007 104: 9242-9247; published online before print May 21 2007, 10.1073/pnas.0703587104 [Abstract] [Full Text] [Figures Only] [PDF]  

Fang Shu, Shun Lv, Yan Qin, Xinlu Ma, Xin Wang, Xiaozhong Peng, Ying Luo, Bing-e Xu, Xiaoqing Sun, and Jun Wu

Functional characterization of human PFTK1 as a cyclin-dependent kinase
PNAS 2007 104: 9248-9253; published online before print May 21 2007, 10.1073/pnas.0703327104 [Abstract] [Full Text] [Figures Only] [PDF]  

Mohammad Mahfuzul Haque, Koustubh Panda, Jesús Tejero, Kulwant S. Aulak, Mohammed Adam Fadlalla, Anthony T. Mustovich, and Dennis J. Stuehr

A connecting hinge represses the activity of endothelial nitric oxide synthase
PNAS 2007 104: 9254-9259; published online before print May 21 2007, 10.1073/pnas.0700332104 [Abstract] [Full Text] [Figures Only] [PDF]  

Biophysics

Erel Levine and Terence Hwa

Stochastic fluctuations in metabolic pathways
PNAS 2007 104: 9224-9229; published online before print May 18 2007, 10.1073/pnas.0610987104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

David L. Bostick and Charles L. Brooks, III

Selectivity in K⁺ channels is due to topological control of the permeant ion's coordinated state
PNAS 2007 104: 9260-9265; published online before print May 22 2007, 10.1073/pnas.0700554104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Quentin le Masne de Chermont, Corinne Chanéac, Johanne Seguin, Fabienne Pellé, Serge Maîtrejean, Jean-Pierre Jolivet, Didier Gourier, Michel Bessodes, and Daniel Scherman

Nanoprobes with near-infrared persistent luminescence for in vivo imaging
PNAS 2007 104: 9266-9271; published online before print May 21 2007, 10.1073/pnas.0702427104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Tomasz L. Religa, Christopher M. Johnson, Dung M. Vu, Scott H. Brewer, R. Brian Dyer, and Alan R. Fersht

The helix–turn–helix motif as an ultrafast independently folding domain: The pathway of folding of Engrailed homeodomain
PNAS 2007 104: 9272-9277; published online before print May 18 2007, 10.1073/pnas.0703434104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Deepak Sharma, Ognjen Perisic, Qing Peng, Yi Cao, Canaan Lam, Hui Lu, and Hongbin Li

Single-molecule force spectroscopy reveals a mechanically stable protein fold and the rational tuning of its mechanical stability
PNAS 2007 104: 9278-9283; published online before print May 21 2007, 10.1073/pnas.0700351104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

Barbara Colombini, M. Angela Bagni, Giovanni Romano, and Giovanni Cecchi

Characterization of actomyosin bond properties in intact skeletal muscle by force spectroscopy
PNAS 2007 104: 9284-9289; published online before print May 21 2007, 10.1073/pnas.0611070104 [Abstract] [Full Text] [Figures Only] [PDF]  

Cell Biology

Bryan M. O'Neill, Shawn J. Szyjka, Ewa T. Lis, Aaron O. Bailey, John R. Yates, III, Oscar M. Aparicio, and Floyd E. Romesberg

Pph3–Psy2 is a phosphatase complex required for Rad53 dephosphorylation and replication fork restart during recovery from DNA damage
PNAS 2007 104: 9290-9295; published online before print May 21 2007, 10.1073/pnas.0703252104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Jingsong Xu, Alexandra Van Keymeulen, Nicole M. Wakida, Pete Carlton, Michael W. Berns, and Henry R. Bourne

Polarity reveals intrinsic cell chirality
PNAS 2007 104: 9296-9300; published online before print May 17 2007, 10.1073/pnas.0703153104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Jen Liou, Marc Fivaz, Takanari Inoue, and Tobias Meyer

Live-cell imaging reveals sequential oligomerization and local plasma membrane targeting of stromal interaction molecule 1 after Ca²⁺ store depletion
PNAS 2007 104: 9301-9306; published online before print May 21 2007, 10.1073/pnas.0702866104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

Sharon C. Braunagel, Shawn T. Williamson, Qi Ding, Xiaogiang Wu, and Max D. Summers Early sorting of inner nuclear membrane proteins is conserved PNAS 2007 104: 9307-9312; published online before print May 21 2007, 10.1073/pnas.0703186104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures] OPEN ACCESS ARTICLE

Developmental Biology

Lizhu Lin, Li Cui, Wenlai Zhou, Daniel Dufort, Xiaoxue Zhang, Chen-Leng Cai, Lei Bu, Lei Yang, Jody Martin, Rolf Kemler, Michael G. Rosenfeld, Ju Chen, and Sylvia M. Evans

-Catenin directly regulates Islet1 expression in cardiovascular progenitors and is required for multiple aspects of cardiogenesis
PNAS 2007 104: 9313-9318; published online before print May 22 2007, 10.1073/pnas.0700923104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figure]  

Di Ai, Xueyao Fu, Jun Wang, Mei-Fang Lu, Li Chen, Antonio Baldini, William H. Klein, and James F. Martin

Canonical Wnt signaling functions in second heart field to promote right ventricular growth
PNAS 2007 104: 9319-9324; published online before print May 22 2007, 10.1073/pnas.0701212104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figure]  

Dan Wang, Jie Hu, I. Alexandru Bobulescu, Timothy A. Quill, Paul McLeroy, Orson W. Moe, and David L. Garbers

A sperm-specific Na⁺/H⁺ exchanger (sNHE) is critical for expression and in vivo bicarbonate regulation of the soluble adenylyl cyclase (sAC)
PNAS 2007 104: 9325-9330; published online before print May 17 2007, 10.1073/pnas.0611296104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Ecology

Jesse R. Barber and William E. Conner

Acoustic mimicry in a predator–prey interaction
PNAS 2007 104: 9331-9334; published online before print May 21 2007, 10.1073/pnas.0703627104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Movies]  

Chelsea L. Wood, James E. Byers, Kathryn L. Cottingham, Irit Altman, Megan J. Donahue, and April M. H. Blakeslee

Parasites alter community structure
PNAS 2007 104: 9335-9339; published online before print May 18 2007, 10.1073/pnas.0700062104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Tables]  

Popko Wiersma, Agustí Muñoz-Garcia, Amy Walker, and Joseph B. Williams

Tropical birds have a slow pace of life
PNAS 2007 104: 9340-9345; published online before print May 21 2007, 10.1073/pnas.0702212104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Evolution

Eugene A. Gladyshev and Irina R. Arkhipova From the Cover: Telomere-associated endonuclease-deficient Penelope-like retroelements in diverse eukaryotes PNAS 2007 104: 9352-9357; published online before print May 4 2007, 10.1073/pnas.0702741104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]   See Commentary on page 9107

Gustavo Caetano-Anollés, Hee Shin Kim, and Jay E. Mittenthal

The origin of modern metabolic networks inferred from phylogenomic analysis of protein architecture
PNAS 2007 104: 9358-9363; published online before print May 21 2007, 10.1073/pnas.0701214104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Luigi Caputi, Nikos Andreakis, Francesco Mastrototaro, Paola Cirino, Mauro Vassillo, and Paolo Sordino

Cryptic speciation in a model invertebrate chordate
PNAS 2007 104: 9364-9369; published online before print May 21 2007, 10.1073/pnas.0610158104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

David L. Dilcher, Ge Sun, Qiang Ji, and Hongqi Li

An early infructescence Hyrcantha decussata (comb. nov.) from the Yixian Formation in northeastern China
PNAS 2007 104: 9370-9374; published online before print May 22 2007, 10.1073/pnas.0703497104 [Abstract] [Full Text] [Figures Only] [PDF]  

Julius Lukes, Isabel L. Mauricio, Gabriele Schönian, Jean-Claude Dujardin, Ketty Soteriadou, Jean-Pierre Dedet, Katrin Kuhls, K. Wilber Quispe Tintaya, Milan Jirku, Eva Chocholová, Christos Haralambous, Francine Pratlong, Miroslav Oborník, Ales Horák, Francisco J. Ayala, and Michael A. Miles

Evolutionary and geographical history of the Leishmania donovani complex with a revision of current taxonomy
PNAS 2007 104: 9375-9380; published online before print May 21 2007, 10.1073/pnas.0703678104 [Abstract] [Full Text] [Figures Only] [PDF]  

Genetics

Jianrong Lu, Marie-Laure Ruhf, Norbert Perrimon, and Philip Leder

A genome-wide RNA interference screen identifies putative chromatin regulators essential for E2F repression
PNAS 2007 104: 9381-9386; published online before print May 17 2007, 10.1073/pnas.0610279104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Fredrik Dahl, Johan Stenberg, Simon Fredriksson, Katrina Welch, Michael Zhang, Mats Nilsson, David Bicknell, Walter F. Bodmer, Ronald W. Davis, and Hanlee Ji Multigene amplification and massively parallel sequencing for cancer mutation discovery PNAS 2007 104: 9387-9392; published online before print May 17 2007, 10.1073/pnas.0702165104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Tables] OPEN ACCESS ARTICLE

Immunology

Eliane Piaggio, Lennart T. Mars, Cécile Cassan, Julie Cabarrocas, Maria Hofstätter, Sabine Desbois, Emilie Bergereau, Olaf Rötzschke, Kirsten Falk, and Roland S. Liblau

Multimerized T cell epitopes protect from experimental autoimmune diabetes by inducing dominant tolerance
PNAS 2007 104: 9393-9398; published online before print May 16 2007, 10.1073/pnas.0610423104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Samir Taoudi and Alexander Medvinsky

Functional identification of the hematopoietic stem cell niche in the ventral domain of the embryonic dorsal aorta
PNAS 2007 104: 9399-9403; published online before print May 17 2007, 10.1073/pnas.0700984104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Medical Sciences

Shannon C. Wieland, John S. Brownstein, Bonnie Berger, and Kenneth D. Mandl

Density-equalizing Euclidean minimum spanning trees for the detection of all disease cluster shapes
PNAS 2007 104: 9404-9409; published online before print May 22 2007, 10.1073/pnas.0609457104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Xiuning Le, David M. Langenau, Matthew D. Keefe, Jeffery L. Kutok, Donna S. Neuberg, and Leonard I. Zon

Heat shock-inducible Cre/Lox approaches to induce diverse types of tumors and hyperplasia in transgenic zebrafish
PNAS 2007 104: 9410-9415; published online before print May 21 2007, 10.1073/pnas.0611302104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Eduard Condac, Robert Silasi-Mansat, Stanley Kosanke, Trenton Schoeb, Rheal Towner, Florea Lupu, Richard D. Cummings, and Myron E. Hinsdale

Polycystic disease caused by deficiency in xylosyltransferase 2, an initiating enzyme of glycosaminoglycan biosynthesis
PNAS 2007 104: 9416-9421; published online before print May 21 2007, 10.1073/pnas.0700908104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Ana P. Goncalvez, Ronald E. Engle, Marisa St. Claire, Robert H. Purcell, and Ching-Juh Lai Monoclonal antibody-mediated enhancement of dengue virus infection in vitro and in vivo and strategies for prevention PNAS 2007 104: 9422-9427; published online before print May 15 2007, 10.1073/pnas.0703498104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Table] OPEN ACCESS ARTICLE

Luisella Cianferotti, Megan Cox, Kristi Skorija, and Marie B. Demay

Vitamin D receptor is essential for normal keratinocyte stem cell function
PNAS 2007 104: 9428-9433; published online before print May 17 2007, 10.1073/pnas.0702884104 [Abstract] [Full Text] [Figures Only] [PDF]  

Giancarlo V. De Ferrari, Andreas Papassotiropoulos, Travis Biechele, Fabienne Wavrant De-Vrieze, Miguel E. Avila, Michael B. Major, Amanda Myers, Katia Sáez, Juan P. Henríquez, Alice Zhao, M. Axel Wollmer, Roger M. Nitsch, Christoph Hock, Chris M. Morris, John Hardy, and Randall T. Moon

Common genetic variation within the Low-Density Lipoprotein Receptor-Related Protein 6 and late-onset Alzheimer's disease
PNAS 2007 104: 9434-9439; published online before print May 21 2007, 10.1073/pnas.0603523104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]