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Table of Contents

June 19, 2007; 104 (25)  [Index By Author]  [Cover Photo]  [Masthead (PDF)]

FROM THE COVER

Molecular defense against retinopathy

Waves of self-assembly

Synthetic ecosystems

Met controls beetle metamorphosis

Antibody therapy for intestinal polyps

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down arrow THIS WEEK IN PNAS

down arrow COMMENTARIES

down arrow PHYSICAL SCIENCES
    Chemistry
    Computer Sciences
    Geology
    Physics

down arrow SOCIAL SCIENCES
    Psychology

down arrow BIOLOGICAL SCIENCES
    Anthropology
    Applied Biological Sciences
    Biochemistry
    Biophysics
    Cell Biology
    Developmental Biology
    Ecology
    Evolution
    Genetics

    Immunology
    Medical Sciences
    Microbiology
    Neuroscience
    Physiology
    Plant Biology
    Sustainability Science

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up arrow THIS WEEK IN PNAS

In This Issue
PNAS 2007 104: 10295-10296. [Full Text] [PDF]  

up arrow COMMENTARIES

Judith H. Willis
Metamorphosis starts with Met
PNAS 2007 104: 10297-10298; published online before print June 12 2007, 10.1073/pnas.0704255104 [Extract] [Full Text] [PDF]  
* See companion article on page 10488

up arrow PHYSICAL SCIENCES

Chemistry

Ya-Jen Chang, Jing-Rong Huang, Yi-Chien Tsai, Jung-Tung Hung, Douglass Wu, Masakazu Fujio, Chi-Huey Wong, and Alice L. Yu
Potent immune-modulating and anticancer effects of NKT cell stimulatory glycolipids
PNAS 2007 104: 10299-10304; published online before print June 12 2007, 10.1073/pnas.0703824104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Rafal Klajn, Kyle J. M. Bishop, and Bartosz A. Grzybowski
Light-controlled self-assembly of reversible and irreversible nanoparticle suprastructures
PNAS 2007 104: 10305-10309; published online before print June 11 2007, 10.1073/pnas.0611371104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Klaus Biemann
On the ability of the Viking gas chromatograph–mass spectrometer to detect organic matter
PNAS 2007 104: 10310-10313; published online before print June 4 2007, 10.1073/pnas.0703732104 [Abstract] [Full Text] [Figures Only] [PDF]  

Roland Mitric, Christian Brgel, and Vlasta Bonaic-Koutecky
Reactivity-promoting criterion based on internal vibrational energy redistribution
PNAS 2007 104: 10314-10317; published online before print June 12 2007, 10.1073/pnas.0704066104 [Abstract] [Full Text] [Figures Only] [PDF]  

Computer Sciences

Florent Krzakala, Andrea Montanari, Federico Ricci-Tersenghi, Guilhem Semerjian, and Lenka Zdeborová
Gibbs states and the set of solutions of random constraint satisfaction problems
PNAS 2007 104: 10318-10323; published online before print June 13 2007, 10.1073/pnas.0703685104 [Abstract] [Full Text] [Figures Only] [PDF]  

Geology

Jonathan L. Payne and Seth Finnegan
The effect of geographic range on extinction risk during background and mass extinction
PNAS 2007 104: 10506-10511; published online before print June 11 2007, 10.1073/pnas.0701257104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Tables] OPEN ACCESS ARTICLE  

Physics

Jack F. Douglas, Kirill Efimenko, Daniel A. Fischer, Fredrick R. Phelan, and Jan Genzer
From the Cover: Propagating waves of self-assembly in organosilane monolayers
PNAS 2007 104: 10324-10329; published online before print June 12 2007, 10.1073/pnas.0703620104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

up arrow SOCIAL SCIENCES

Psychology

Myeong-Ho Sohn, Mark V. Albert, Kwanjin Jung, Cameron S. Carter, and John R. Anderson
Anticipation of conflict monitoring in the anterior cingulate cortex and the prefrontal cortex
PNAS 2007 104: 10330-10334; published online before print June 11 2007, 10.1073/pnas.0703225104 [Abstract] [Full Text] [Figures Only] [PDF]  

up arrow BIOLOGICAL SCIENCES

Anthropology

Alice A. Storey, José Miguel Ramírez, Daniel Quiroz, David V. Burley, David J. Addison, Richard Walter, Atholl J. Anderson, Terry L. Hunt, J. Stephen Athens, Leon Huynen, and Elizabeth A. Matisoo-Smith
Radiocarbon and DNA evidence for a pre-Columbian introduction of Polynesian chickens to Chile
PNAS 2007 104: 10335-10339; published online before print June 7 2007, 10.1073/pnas.0703993104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Text]  

Applied Biological Sciences

Paul A. Wender, Elena A. Goun, Lisa R. Jones, Thomas H. Pillow, Jonathan B. Rothbard, Rajesh Shinde, and Christopher H. Contag
Real-time analysis of uptake and bioactivatable cleavage of luciferin-transporter conjugates in transgenic reporter mice
PNAS 2007 104: 10340-10345; published online before print June 11 2007, 10.1073/pnas.0703919104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Biochemistry

Masaki Mishima, Ryoko Maesaki, Miyuki Kasa, Takashi Watanabe, Masaki Fukata, Kozo Kaibuchi, and Toshio Hakoshima
Structural basis for tubulin recognition by cytoplasmic linker protein 170 and its autoinhibition
PNAS 2007 104: 10346-10351; published online before print June 11 2007, 10.1073/pnas.0703876104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Yi Zhou, Deanna M. Navaroli, Metewo Selase Enuameh, and Craig T. Martin
Dissociation of halted T7 RNA polymerase elongation complexes proceeds via a forward-translocation mechanism
PNAS 2007 104: 10352-10357; published online before print June 6 2007, 10.1073/pnas.0606306104 [Abstract] [Full Text] [Figures Only] [PDF]  

Sonata Jurenaite-Urbanaviciene, Jurgita Serksnaite, Edita Kriukiene, Jolanta Giedriene, Ceslovas Venclovas, and Arvydas Lubys
Generation of DNA cleavage specificities of type II restriction endonucleases by reassortment of target recognition domains
PNAS 2007 104: 10358-10363; published online before print June 6 2007, 10.1073/pnas.0610365104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Marcus B. Smolka, Claudio P. Albuquerque, Sheng-hong Chen, and Huilin Zhou
Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases
PNAS 2007 104: 10364-10369; published online before print June 11 2007, 10.1073/pnas.0701622104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Tables]  

Julien Viaud, Mahel Zeghouf, Hélène Barelli, Jean-Christophe Zeeh, André Padilla, Bernard Guibert, Pierre Chardin, Catherine A. Royer, Jacqueline Cherfils, and Alain Chavanieu
Structure-based discovery of an inhibitor of Arf activation by Sec7 domains through targeting of protein–protein complexes
PNAS 2007 104: 10370-10375; published online before print June 11 2007, 10.1073/pnas.0700773104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Daniel W. Udwary, Lisa Zeigler, Ratnakar N. Asolkar, Vasanth Singan, Alla Lapidus, William Fenical, Paul R. Jensen, and Bradley S. Moore
Genome sequencing reveals complex secondary metabolome in the marine actinomycete Salinispora tropica
PNAS 2007 104: 10376-10381; published online before print June 11 2007, 10.1073/pnas.0700962104 [Abstract] [Full Text] [Figures Only] [PDF]  

Jade K. Forwood, Anil S. Thakur, Gregor Guncar, Mary Marfori, Dmitri Mouradov, Weining Meng, Jodie Robinson, Thomas Huber, Stuart Kellie, Jennifer L. Martin, David A. Hume, and Bostjan Kobe
Structural basis for recruitment of tandem hotdog domains in acyl-CoA thioesterase 7 and its role in inflammation
PNAS 2007 104: 10382-10387; published online before print June 11 2007, 10.1073/pnas.0700974104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Magdalena Korczynska, Tariq A. Mukhtar, Gerard D. Wright, and Albert M. Berghuis
Structural basis for streptogramin B resistance in Staphylococcus aureus by virginiamycin B lyase
PNAS 2007 104: 10388-10393; published online before print June 11 2007, 10.1073/pnas.0701809104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Ashwini S. Kamath-Loeb, Li Lan, Satoshi Nakajima, Akira Yasui, and Lawrence A. Loeb
Werner syndrome protein interacts functionally with translesion DNA polymerases
PNAS 2007 104: 10394-10399; published online before print June 11 2007, 10.1073/pnas.0702513104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Nazif Alic, Nayla Ayoub, Emilie Landrieux, Emmanuel Favry, Peggy Baudouin-Cornu, Michel Riva, and Christophe Carles
Selectivity and proofreading both contribute significantly to the fidelity of RNA polymerase III transcription
PNAS 2007 104: 10400-10405; published online before print June 6 2007, 10.1073/pnas.0704116104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Sheng Wang and K. Andrew White
Riboswitching on RNA virus replication
PNAS 2007 104: 10406-10411; published online before print June 6 2007, 10.1073/pnas.0704178104 [Abstract] [Full Text] [Figures Only] [PDF]  

Nicholas K. Conrad, Mei-Di Shu, Katherine E. Uyhazi, and Joan A. Steitz
Mutational analysis of a viral RNA element that counteracts rapid RNA decay by interaction with the polyadenylate tail
PNAS 2007 104: 10412-10417; published online before print June 11 2007, 10.1073/pnas.0704187104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Nicholas G. Nickols and Peter B. Dervan
Suppression of androgen receptor-mediated gene expression by a sequence-specific DNA-binding polyamide
PNAS 2007 104: 10418-10423; published online before print June 12 2007, 10.1073/pnas.0704217104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Yilin Hu, Aaron W. Fay, Chi Chung Lee, and Markus W. Ribbe
P-cluster maturation on nitrogenase MoFe protein
PNAS 2007 104: 10424-10429; published online before print June 11 2007, 10.1073/pnas.0704297104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Biophysics

Del Lucent, V. Vishal, and Vijay S. Pande
Protein folding under confinement: A role for solvent
PNAS 2007 104: 10430-10434; published online before print June 11 2007, 10.1073/pnas.0608256104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Wilfried Weber, Marie Daoud-El Baba, and Martin Fussenegger
From the Cover: Synthetic ecosystems based on airborne inter- and intrakingdom communication
PNAS 2007 104: 10435-10440; published online before print June 5 2007, 10.1073/pnas.0701382104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Text] OPEN ACCESS ARTICLE  

Engel G. Vrieling, Qianyao Sun, Mingwen Tian, Patricia J. Kooyman, Winfried W. C. Gieskes, Rutger A. van Santen, and Nico A. J. M. Sommerdijk
Salinity-dependent diatom biosilicification implies an important role of external ionic strength
PNAS 2007 104: 10441-10446; published online before print June 11 2007, 10.1073/pnas.0608980104 [Abstract] [Full Text] [Figures Only] [PDF]  

Audrey Fischer and Mauricio Montal
Single molecule detection of intermediates during botulinum neurotoxin translocation across membranes
PNAS 2007 104: 10447-10452; published online before print June 11 2007, 10.1073/pnas.0700046104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Masahito Kinoshita, Kiyoto Kamagata, Akio Maeda, Yuji Goto, Tamiki Komatsuzaki, and Satoshi Takahashi
Development of a technique for the investigation of folding dynamics of single proteins for extended time periods
PNAS 2007 104: 10453-10458; published online before print June 11 2007, 10.1073/pnas.0700267104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Huimin Chen, Elizabeth Rhoades, James S. Butler, Stewart N. Loh, and Watt W. Webb
Dynamics of equilibrium structural fluctuations of apomyoglobin measured by fluorescence correlation spectroscopy
PNAS 2007 104: 10459-10464; published online before print June 7 2007, 10.1073/pnas.0704073104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Cell Biology

Jian-Guo Ren, Zhigang Li, and David B. Sacks
IQGAP1 modulates activation of B-Raf
PNAS 2007 104: 10465-10469; published online before print June 11 2007, 10.1073/pnas.0611308104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

Rowena R. Ramos, Andrea J. Swanson, and Joseph Bass
Calreticulin and Hsp90 stabilize the human insulin receptor and promote its mobility in the endoplasmic reticulum
PNAS 2007 104: 10470-10475; published online before print June 11 2007, 10.1073/pnas.0701114104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figure]  

I. Zucchi, S. Sanzone, S. Astigiano, P. Pelucchi, M. Scotti, V. Valsecchi, O. Barbieri, G. Bertoli, A. Albertini, R. A. Reinbold, and R. Dulbecco
The properties of a mammary gland cancer stem cell
PNAS 2007 104: 10476-10481; published online before print June 12 2007, 10.1073/pnas.0703071104 [Abstract] [Full Text] [Figures Only] [PDF]  

Shuibing Chen, Shinichi Takanashi, Qisheng Zhang, Wen Xiong, Shoutian Zhu, Eric C. Peters, Sheng Ding, and Peter G. Schultz
Reversine increases the plasticity of lineage-committed mammalian cells
PNAS 2007 104: 10482-10487; published online before print June 12 2007, 10.1073/pnas.0704360104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Developmental Biology

Barbora Konopova and Marek Jindra
From the Cover: Juvenile hormone resistance gene Methoprene-tolerant controls entry into metamorphosis in the beetle Tribolium castaneum
PNAS 2007 104: 10488-10493; published online before print May 30 2007, 10.1073/pnas.0703719104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  
* See Commentary on page 10297

Jianchang Yang, Li Chai, Fang Liu, Louis M. Fink, Pei Lin, Leslie E. Silberstein, Hesham M. Amin, David C. Ward, and Yupo Ma
Bmi-1 is a target gene for SALL4 in hematopoietic and leukemic cells
PNAS 2007 104: 10494-10499; published online before print June 8 2007, 10.1073/pnas.0704001104 [Abstract] [Full Text] [Figures Only] [PDF]  

F. C. Lynn, S. B. Smith, M. E. Wilson, K. Y. Yang, N. Nekrep, and M. S. German
Sox9 coordinates a transcriptional network in pancreatic progenitor cells
PNAS 2007 104: 10500-10505; published online before print June 11 2007, 10.1073/pnas.0704054104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Ecology

Jonathan L. Payne and Seth Finnegan
The effect of geographic range on extinction risk during background and mass extinction
PNAS 2007 104: 10506-10511; published online before print June 11 2007, 10.1073/pnas.0701257104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Tables] OPEN ACCESS ARTICLE  

Jeremy D. Long, Gabriela W. Smalley, Todd Barsby, Jon T. Anderson, and Mark E. Hay
Chemical cues induce consumer-specific defenses in a bloom-forming marine phytoplankton
PNAS 2007 104: 10512-10517; published online before print June 11 2007, 10.1073/pnas.0611600104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Table]  

Georgi M. Daskalov, Alexander N. Grishin, Sergei Rodionov, and Vesselina Mihneva
Trophic cascades triggered by overfishing reveal possible mechanisms of ecosystem regime shifts
PNAS 2007 104: 10518-10523; published online before print June 4 2007, 10.1073/pnas.0701100104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Naoaki Yamamoto, Jun Yokoyama, and Masakado Kawata
Relative resource abundance explains butterfly biodiversity in island communities
PNAS 2007 104: 10524-10529; published online before print June 6 2007, 10.1073/pnas.0701583104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE  

Margarita Caso, Charlotte González-Abraham, and Exequiel Ezcurra
Divergent ecological effects of oceanographic anomalies on terrestrial ecosystems of the Mexican Pacific coast
PNAS 2007 104: 10530-10535; published online before print June 11 2007, 10.1073/pnas.0701862104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Table]  

Torsten Will, W. Fred Tjallingii, Alexandra Thönnessen, and Aart J. E. van Bel
Molecular sabotage of plant defense by aphid saliva
PNAS 2007 104: 10536-10541; published online before print June 6 2007, 10.1073/pnas.0703535104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Evolution

Alfredo Villasante, José P. Abad, and María Méndez-Lago
Centromeres were derived from telomeres during the evolution of the eukaryotic chromosome
PNAS 2007 104: 10542-10547; published online before print June 8 2007, 10.1073/pnas.0703808104 [Abstract] [Full Text] [Figures Only] [PDF]  

Melissa M. Holmes, Greta J. Rosen, Cynthia L. Jordan, Geert J. de Vries, Bruce D. Goldman, and Nancy G. Forger
Social control of brain morphology in a eusocial mammal
PNAS 2007 104: 10548-10552; published online before print June 7 2007, 10.1073/pnas.0610344104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Table]  

Ethan O. Perlstein, Eric J. Deeds, Orr Ashenberg, Eugene I. Shakhnovich, and Stuart L. Schreiber
Quantifying fitness distributions and phenotypic relationships in recombinant yeast populations
PNAS 2007 104: 10553-10558; published online before print June 12 2007, 10.1073/pnas.0704037104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figure]  

Genetics

Matthew A. Wright, Peter Kharchenko, George M. Church, and Daniel Segrè
Chromosomal periodicity of evolutionarily conserved gene pairs
PNAS 2007 104: 10559-10564; published online before print June 11 2007, 10.1073/pnas.0610776104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE  

William M. Winston, Marie Sutherlin, Amanda J. Wright, Evan H. Feinberg, and Craig P. Hunter
Caenorhabditis elegans SID-2 is required for environmental RNA interference
PNAS 2007 104: 10565-10570; published online before print June 11 2007, 10.1073/pnas.0611282104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Sam Stoler, Kelly Rogers, Scott Weitze, Lisa Morey, Molly Fitzgerald-Hayes, and Richard E. Baker
Scm3, an essential Saccharomyces cerevisiae centromere protein required for G2/M progression and Cse4 localization
PNAS 2007 104: 10571-10576; published online before print June 4 2007, 10.1073/pnas.0703178104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE  

Immunology

Javier Rangel-Moreno, Juan E. Moyron-Quiroz, Louise Hartson, Kim Kusser, and Troy D. Randall
Pulmonary expression of CXC chemokine ligand 13, CC chemokine ligand 19, and CC chemokine ligand 21 is essential for local immunity to influenza
PNAS 2007 104: 10577-10582; published online before print June 11 2007, 10.1073/pnas.0700591104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

Qingrong Yan, Vladimir N. Malashkevich, Alexander Fedorov, Elena Fedorov, Erhu Cao, Jeffrey W. Lary, James L. Cole, Stanley G. Nathenson, and Steven C. Almo
Structure of CD84 provides insight into SLAM family function
PNAS 2007 104: 10583-10588; published online before print June 11 2007, 10.1073/pnas.0703893104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Medical Sciences

Ya-Jen Chang, Jing-Rong Huang, Yi-Chien Tsai, Jung-Tung Hung, Douglass Wu, Masakazu Fujio, Chi-Huey Wong, and Alice L. Yu
Potent immune-modulating and anticancer effects of NKT cell stimulatory glycolipids
PNAS 2007 104: 10299-10304; published online before print June 12 2007, 10.1073/pnas.0703824104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Chatarina Lofqvist, Jing Chen, Kip M. Connor, Alexandra C. H. Smith, Christopher M. Aderman, Nan Liu, John E. Pintar, Thomas Ludwig, Ann Hellstrom, and Lois E. H. Smith
From the Cover: IGFBP3 suppresses retinopathy through suppression of oxygen-induced vessel loss and promotion of vascular regrowth
PNAS 2007 104: 10589-10594; published online before print June 13 2007, 10.1073/pnas.0702031104 [Abstract] [Full Text] [Figures Only] [PDF]  

Kyung-Hee Chang, Tailoi Chan-Ling, Evan L. McFarland, Aqeela Afzal, Hao Pan, Louise C. Baxter, Lynn C. Shaw, Sergio Caballero, Nilanjana Sengupta, Sergio Li Calzi, Sean M. Sullivan, and Maria B. Grant
IGF binding protein-3 regulates hematopoietic stem cell and endothelial precursor cell function during vascular development
PNAS 2007 104: 10595-10600; published online before print June 13 2007, 10.1073/pnas.0702072104 [Abstract] [Full Text] [Figures Only] [PDF]  

Noam Zelcer, Negar Khanlou, Ryan Clare, Qingguang Jiang, Erin G. Reed-Geaghan, Gary E. Landreth, Harry V. Vinters, and Peter Tontonoz
Attenuation of neuroinflammation and Alzheimer's disease pathology by liver x receptors
PNAS 2007 104: 10601-10606; published online before print June 11 2007, 10.1073/pnas.0701096104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE  

Neil L. Spector, Yosef Yarden, Bradley Smith, Ljuba Lyass, Patricia Trusk, Karen Pry, Jason E. Hill, Wenle Xia, Rony Seger, and Sarah S. Bacus
Activation of AMP-activated protein kinase by human EGF receptor 2/EGF receptor tyrosine kinase inhibitor protects cardiac cells
PNAS 2007 104: 10607-10612; published online before print June 7 2007, 10.1073/pnas.0701286104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Yun-wu Zhang, Ruishan Wang, Qiang Liu, Han Zhang, Francesca-Fang Liao, and Huaxi Xu
Presenilin/{gamma}-secretase-dependent processing of beta-amyloid precursor protein regulates EGF receptor expression
PNAS 2007 104: 10613-10618; published online before print June 7 2007, 10.1073/pnas.0703903104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE  

Leonard Buckbinder, David T. Crawford, Hong Qi, Hua Zhu Ke, Lisa M. Olson, Kelly R. Long, Peter C. Bonnette, Amy P. Baumann, John E. Hambor, William A. Grasser, III, Lydia C. Pan, Thomas A. Owen, Michael J. Luzzio, Catherine A. Hulford, David F. Gebhard, Vishwas M. Paralkar, Hollis A. Simmons, John C. Kath, W. Gregory Roberts, Steven L. Smock, Angel Guzman-Perez, Thomas A. Brown, and Mei Li
Proline-rich tyrosine kinase 2 regulates osteoprogenitor cells and bone formation, and offers an anabolic treatment approach for osteoporosis
PNAS 2007 104: 10619-10624; published online before print May 30 2007, 10.1073/pnas.0701421104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE  

Nina Korsisaari, Ian M. Kasman, William F. Forrest, Navneet Pal, Wei Bai, Germaine Fuh, Franklin V. Peale, Ron Smits, and Napoleone Ferrara
From the Cover: Inhibition of VEGF-A prevents the angiogenic switch and results in increased survival of Apc+/min mice
PNAS 2007 104: 10625-10630; published online before print June 6 2007, 10.1073/pnas.0704213104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE  

Microbiology

Tobias J. Erb, Ivan A. Berg, Volker Brecht, Michael Müller, Georg Fuchs, and Birgit E. Alber
Synthesis of C5-dicarboxylic acids from C2-units involving crotonyl-CoA carboxylase/reductase: The ethylmalonyl-CoA pathway
PNAS 2007 104: 10631-10636; published online before print June 4 2007, 10.1073/pnas.0702791104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

María A. Rendón, Zeus Saldaña, Aysen L. Erdem, Valério Monteiro-Neto, Alejandra Vázquez, James B. Kaper, José L. Puente, and Jorge A. Girón
Commensal and pathogenic Escherichia coli use a common pilus adherence factor for epithelial cell colonization
PNAS 2007 104: 10637-10642; published online before print June 11 2007, 10.1073/pnas.0704104104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE  

Buck S. Samuel, Elizabeth E. Hansen, Jill K. Manchester, Pedro M. Coutinho, Bernard Henrissat, Robert Fulton, Philippe Latreille, Kung Kim, Richard K. Wilson, and Jeffrey I. Gordon
Genomic and metabolic adaptations of Methanobrevibacter smithii to the human gut
PNAS 2007 104: 10643-10648; published online before print June 11 2007, 10.1073/pnas.0704189104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE  

Christiane Honisch, Yong Chen, Chloe Mortimer, Catherine Arnold, Oliver Schmidt, Dirk van den Boom, Charles R. Cantor, Haroun N. Shah, and Saheer E. Gharbia
Automated comparative sequence analysis by base-specific cleavage and mass spectrometry for nucleic acid-based microbial typing
PNAS 2007 104: 10649-10654; published online before print June 11 2007, 10.1073/pnas.0704152104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE  

Neuroscience

Anna K. Clark, Ping K. Yip, John Grist, Clive Gentry, Amelia A. Staniland, Fabien Marchand, Maliheh Dehvari, Glen Wotherspoon, Janet Winter, Jakir Ullah, Stuart Bevan, and Marzia Malcangio
Inhibition of spinal microglial cathepsin S for the reversal of neuropathic pain
PNAS 2007 104: 10655-10660; published online before print June 5 2007, 10.1073/pnas.0610811104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Luc Mallet, Michael Schüpbach, Karim N'Diaye, Philippe Remy, Eric Bardinet, Virginie Czernecki, Marie-Laure Welter, Antoine Pelissolo, Merle Ruberg, Yves Agid, and Jérôme Yelnik
Stimulation of subterritories of the subthalamic nucleus reveals its role in the integration of the emotional and motor aspects of behavior
PNAS 2007 104: 10661-10666; published online before print June 7 2007, 10.1073/pnas.0610849104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Text]  

Henning U. Voss, Karsten Tabelow, Jörg Polzehl, Ofer Tchernichovski, Kristen K. Maul, Delanthi Salgado-Commissariat, Douglas Ballon, and Santosh A. Helekar
Functional MRI of the zebra finch brain during song stimulation suggests a lateralized response topography
PNAS 2007 104: 10667-10672; published online before print June 11 2007, 10.1073/pnas.0611515104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Jae-Eun Kang, John R. Cirrito, Hongxin Dong, John G. Csernansky, and David M. Holtzman
Acute stress increases interstitial fluid amyloid-beta via corticotropin-releasing factor and neuronal activity
PNAS 2007 104: 10673-10678; published online before print June 5 2007, 10.1073/pnas.0700148104 [Abstract] [Full Text] [Figures Only] [PDF]  

El Mus, Patrick R. Hof, and Henri Tiedge
Dendritic BC200 RNA in aging and in Alzheimer's disease
PNAS 2007 104: 10679-10684; published online before print June 6 2007, 10.1073/pnas.0701532104 [Abstract] [Full Text] [Figures Only] [PDF]  

Rhîannan H. Williams, Lise T. Jensen, Alex Verkhratsky, Lars Fugger, and Denis Burdakov
Control of hypothalamic orexin neurons by acid and CO2
PNAS 2007 104: 10685-10690; published online before print June 11 2007, 10.1073/pnas.0702676104 [Abstract] [Full Text] [Figures Only] [PDF]  

Physiology

Morris F. Tansky, Charalabos Pothoulakis, and Susan E. Leeman
Functional consequences of alteration of N-linked glycosylation sites on the neurokinin 1 receptor
PNAS 2007 104: 10691-10696; published online before print June 11 2007, 10.1073/pnas.0703394104 [Abstract] [Full Text] [Figures Only] [PDF]  

Youngsoo Kim, Aaron D. Laposky, Bernard M. Bergmann, and Fred W. Turek
Repeated sleep restriction in rats leads to homeostatic and allostatic responses during recovery sleep
PNAS 2007 104: 10697-10702; published online before print June 4 2007, 10.1073/pnas.0610351104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE  

Nassim Dali-Youcef, Chikage Mataki, Agnès Coste, Nadia Messaddeq, Sylvain Giroud, Stéphane Blanc, Christian Koehl, Marie-France Champy, Pierre Chambon, Lluis Fajas, Daniel Metzger, Kristina Schoonjans, and Johan Auwerx
Adipose tissue-specific inactivation of the retinoblastoma protein protects against diabesity because of increased energy expenditure
PNAS 2007 104: 10703-10708; published online before print June 7 2007, 10.1073/pnas.0611568104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Pablo Garcia-Roves, Janice M. Huss, Dong-Ho Han, Chad R. Hancock, Eduardo Iglesias-Gutierrez, May Chen, and John O. Holloszy
Raising plasma fatty acid concentration induces increased biogenesis of mitochondria in skeletal muscle
PNAS 2007 104: 10709-10713; published online before print June 4 2007, 10.1073/pnas.0704024104 [Abstract] [Full Text] [Figures Only] [PDF]  

Xavier d'Anglemont de Tassigny, Lisa A. Fagg, John P. C. Dixon, Kate Day, Harry G. Leitch, Alan G. Hendrick, Dirk Zahn, Isabelle Franceschini, Alain Caraty, Mark B. L. Carlton, Samuel A. J. R. Aparicio, and William H. Colledge
Hypogonadotropic hypogonadism in mice lacking a functional Kiss1 gene
PNAS 2007 104: 10714-10719; published online before print June 11 2007, 10.1073/pnas.0704114104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Table]  

Plant Biology

Akiko Sugio, Bing Yang, Tong Zhu, and Frank F. White
Two type III effector genes of Xanthomonas oryzae pv. oryzae control the induction of the host genes OsTFIIA{gamma}1 and OsTFX1 during bacterial blight of rice
PNAS 2007 104: 10720-10725; published online before print June 11 2007, 10.1073/pnas.0701742104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Anthony Gobert, Stanislav Isayenkov, Camilla Voelker, Katrin Czempinski, and Frans J. M. Maathuis
The two-pore channel TPK1 gene encodes the vacuolar K+ conductance and plays a role in K+ homeostasis
PNAS 2007 104: 10726-10731; published online before print June 11 2007, 10.1073/pnas.0702595104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

Alisa Huffaker and Clarence A. Ryan
Endogenous peptide defense signals in Arabidopsis differentially amplify signaling for the innate immune response
PNAS 2007 104: 10732-10736; published online before print June 12 2007, 10.1073/pnas.0703343104 [Abstract] [Full Text] [Figures Only] [PDF]  

Jutta Rösler, Ilse Klein, and Mathias Zeidler
Arabidopsis fhl/fhy1 double mutant reveals a distinct cytoplasmic action of phytochrome A
PNAS 2007 104: 10737-10742; published online before print June 12 2007, 10.1073/pnas.0703855104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

Sustainability Science

Jonathan R. Thompson, Thomas A. Spies, and Lisa M. Ganio
Reburn severity in managed and unmanaged vegetation in a large wildfire
PNAS 2007 104: 10743-10748; published online before print June 11 2007, 10.1073/pnas.0700229104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Table]  

up arrow CORRECTIONS

Correction for Elena Goicoechea de Jorge et al., Gain-of-function mutations in complement factor B are associated with atypical hemolytic uremic syndrome [Full Text] [Figures Only] [PDF]  

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