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THIS WEEK IN PNAS

In This Issue
PNAS 2007 104: 687-688. [Full Text] [PDF]  

COMMENTARIES

K. G. Murphy and S. R. Bloom

Nonpeptidic glucagon-like peptide 1 receptor agonists: A magic bullet for diabetes?
PNAS 2007 104: 689-690; published online before print January 9 2007, 10.1073/pnas.0610679104 [Extract] [Full Text] [Figures Only] [PDF]  
See companion article on page 937
See companion article on page 943

Jennifer L. Bishop, Erin C. Boyle, and B. Brett Finlay

Deception point: Peptidoglycan modification as a means of immune evasion
PNAS 2007 104: 691-692; published online before print January 12 2007, 10.1073/pnas.0611133104 [Extract] [Full Text] [Figures Only] [PDF]  
See companion article on page 997

PROFILES

Tinsley H. Davis

Profile of J. Woodland Hastings
PNAS 2007 104: 693-695; published online before print January 10 2007, 10.1073/pnas.0610519104 [Extract] [Full Text] [Figures Only] [PDF]  

PHYSICAL SCIENCES

Applied Mathematics

Cyrill B. Muratov, Eric Vanden-Eijnden, and Weinan E

Noise can play an organizing role for the recurrent dynamics in excitable media
PNAS 2007 104: 702-707; published online before print January 8 2007, 10.1073/pnas.0607433104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Jasper A. Vrugt and Bruce A. Robinson Improved evolutionary optimization from genetically adaptive multimethod search PNAS 2007 104: 708-711; published online before print January 10 2007, 10.1073/pnas.0610471104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Chemistry

Ting Chen, Zhenli Zhang, and Sharon C. Glotzer

A precise packing sequence for self-assembled convex structures
PNAS 2007 104: 717-722; published online before print January 10 2007, 10.1073/pnas.0604239104 [Abstract] [Full Text] [Figures Only] [PDF]  

Tatiana R. Prytkova, David N. Beratan, and Spiros S. Skourtis

Photoselected electron transfer pathways in DNA photolyase
PNAS 2007 104: 802-807; published online before print January 5 2007, 10.1073/pnas.0605319104 [Abstract] [Full Text] [Figures Only] [PDF]  

Tom Young, Robert Abel, Byungchan Kim, Bruce J. Berne, and Richard A. Friesner

Motifs for molecular recognition exploiting hydrophobic enclosure in protein–ligand binding
PNAS 2007 104: 808-813; published online before print January 4 2007, 10.1073/pnas.0610202104 [Abstract] [Full Text] [Figures Only] [PDF]  

Computer Sciences

Manuel Rueda, Carles Ferrer-Costa, Tim Meyer, Alberto Pérez, Jordi Camps, Adam Hospital, Josep Lluis Gelpí, and Modesto Orozco

A consensus view of protein dynamics
PNAS 2007 104: 796-801; published online before print January 10 2007, 10.1073/pnas.0605534104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Mathematics

Alberto Parmeggiani

On positivity of certain systems of partial differential equations
PNAS 2007 104: 723-726; published online before print January 9 2007, 10.1073/pnas.0609949104 [Abstract] [Full Text] [PDF]  

Physics

Chi-Cheng Fu, Hsu-Yang Lee, Kowa Chen, Tsong-Shin Lim, Hsiao-Yun Wu, Po-Keng Lin, Pei-Kuen Wei, Pei-Hsi Tsao, Huan-Cheng Chang, and Wunshain Fann

Characterization and application of single fluorescent nanodiamonds as cellular biomarkers
PNAS 2007 104: 727-732; published online before print January 9 2007, 10.1073/pnas.0605409104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Manoj V. Athawale, Gaurav Goel, Tuhin Ghosh, Thomas M. Truskett, and Shekhar Garde Effects of lengthscales and attractions on the collapse of hydrophobic polymers in water PNAS 2007 104: 733-738; published online before print January 10 2007, 10.1073/pnas.0605139104 [Abstract] [Full Text] [Figures Only] [PDF] OPEN ACCESS ARTICLE

SOCIAL SCIENCES

Anthropology

Economic Sciences

Ryan D. Oprea, Vernon L. Smith, and Abel M. Winn

A compensation election for binary social choice
PNAS 2007 104: 1093-1096; published online before print January 10 2007, 10.1073/pnas.0609866104 [Abstract] [Full Text] [Figures Only] [PDF]  

Psychology

G. V. Drivonikou, P. Kay, T. Regier, R. B. Ivry, A. L. Gilbert, A. Franklin, and I. R. L. Davies

Further evidence that Whorfian effects are stronger in the right visual field than the left
PNAS 2007 104: 1097-1102; published online before print January 9 2007, 10.1073/pnas.0610132104 [Abstract] [Full Text] [Figures Only] [PDF]  

BIOLOGICAL SCIENCES

Anthropology

Mélanie Pruvost, Reinhard Schwarz, Virginia Bessa Correia, Sophie Champlot, Séverine Braguier, Nicolas Morel, Yolanda Fernandez-Jalvo, Thierry Grange, and Eva-Maria Geigl

Freshly excavated fossil bones are best for amplification of ancient DNA
PNAS 2007 104: 739-744; published online before print January 8 2007, 10.1073/pnas.0610257104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Biochemistry

Xiaodong Zhang, Swarnalatha Y. Reddy, and Thomas C. Bruice

Mechanism of methanol oxidation by quinoprotein methanol dehydrogenase
PNAS 2007 104: 745-749; published online before print January 10 2007, 10.1073/pnas.0610126104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

M. Joanne Lemieux, Sarah J. Fischer, Maia M. Cherney, Katherine S. Bateman, and Michael N. G. James

The crystal structure of the rhomboid peptidase from Haemophilus influenzae provides insight into intramembrane proteolysis
PNAS 2007 104: 750-754; published online before print January 8 2007, 10.1073/pnas.0609981104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Lauren E. Frick, James C. Delaney, Cintyu Wong, Catherine L. Drennan, and John M. Essigmann

Alleviation of 1,N⁶-ethanoadenine genotoxicity by the Escherichia coli adaptive response protein AlkB
PNAS 2007 104: 755-760; published online before print January 9 2007, 10.1073/pnas.0607377104 [Abstract] [Full Text] [Figures Only] [PDF]  

Biophysics

Cyrill B. Muratov, Eric Vanden-Eijnden, and Weinan E

Noise can play an organizing role for the recurrent dynamics in excitable media
PNAS 2007 104: 702-707; published online before print January 8 2007, 10.1073/pnas.0607433104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

P. Ziherl and S. Svetina Flat and sigmoidally curved contact zones in vesicle–vesicle adhesion PNAS 2007 104: 761-765; published online before print January 10 2007, 10.1073/pnas.0607633104 [Abstract] [Full Text] [Figures Only] [PDF] OPEN ACCESS ARTICLE

Moeava Tehei, Bruno Franzetti, Kathleen Wood, Frank Gabel, Elisa Fabiani, Marion Jasnin, Michaela Zamponi, Dieter Oesterhelt, Giuseppe Zaccai, Margaret Ginzburg, and Ben-Zion Ginzburg From the Cover: Neutron scattering reveals extremely slow cell water in a Dead Sea organism PNAS 2007 104: 766-771; published online before print January 10 2007, 10.1073/pnas.0601639104 [Abstract] [Full Text] [Figures Only] [PDF]

Zev Bryant, David Altman, and James A. Spudich The power stroke of myosin VI and the basis of reverse directionality PNAS 2007 104: 772-777; published online before print December 20 2006, 10.1073/pnas.0610144104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Hyokeun Park, Anna Li, Li-Qiong Chen, Anne Houdusse, Paul R. Selvin, and H. Lee Sweeney The unique insert at the end of the myosin VI motor is the sole determinant of directionality PNAS 2007 104: 778-783; published online before print January 9 2007, 10.1073/pnas.0610066104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Movies] OPEN ACCESS ARTICLE

Kae-Jung Hwang, Fatemeh Mahmoodian, James A. Ferretti, Edward D. Korn, and James M. Gruschus

Intramolecular interaction in the tail of Acanthamoeba myosin IC between the SH3 domain and a putative pleckstrin homology domain
PNAS 2007 104: 784-789; published online before print January 10 2007, 10.1073/pnas.0610231104 [Abstract] [Full Text] [Figures Only] [PDF]  

Ayako Egawa, Toshimichi Fujiwara, Tadashi Mizoguchi, Yoshinori Kakitani, Yasushi Koyama, and Hideo Akutsu

Structure of the light-harvesting bacteriochlorophyll c assembly in chlorosomes from Chlorobium limicola determined by solid-state NMR
PNAS 2007 104: 790-795; published online before print January 10 2007, 10.1073/pnas.0605911104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Manuel Rueda, Carles Ferrer-Costa, Tim Meyer, Alberto Pérez, Jordi Camps, Adam Hospital, Josep Lluis Gelpí, and Modesto Orozco

A consensus view of protein dynamics
PNAS 2007 104: 796-801; published online before print January 10 2007, 10.1073/pnas.0605534104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Tatiana R. Prytkova, David N. Beratan, and Spiros S. Skourtis

Photoselected electron transfer pathways in DNA photolyase
PNAS 2007 104: 802-807; published online before print January 5 2007, 10.1073/pnas.0605319104 [Abstract] [Full Text] [Figures Only] [PDF]  

Tom Young, Robert Abel, Byungchan Kim, Bruce J. Berne, and Richard A. Friesner

Motifs for molecular recognition exploiting hydrophobic enclosure in protein–ligand binding
PNAS 2007 104: 808-813; published online before print January 4 2007, 10.1073/pnas.0610202104 [Abstract] [Full Text] [Figures Only] [PDF]  

Pierre Aller, Mark A. Rould, Matthew Hogg, Susan S. Wallace, and Sylvie Doublié

A structural rationale for stalling of a replicative DNA polymerase at the most common oxidative thymine lesion, thymine glycol
PNAS 2007 104: 814-818; published online before print January 8 2007, 10.1073/pnas.0606648104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figure]  

Cell Biology

Bin Zheng and Lewis C. Cantley

Regulation of epithelial tight junction assembly and disassembly by AMP-activated protein kinase
PNAS 2007 104: 819-822; published online before print January 4 2007, 10.1073/pnas.0610157104 [Abstract] [Full Text] [Figures Only] [PDF]  

Nienwen Chow, Robert D. Bell, Rashid Deane, Jeffrey W. Streb, Jiyuan Chen, Andrew Brooks, William Van Nostrand, Joseph M. Miano, and Berislav V. Zlokovic

Serum response factor and myocardin mediate arterial hypercontractility and cerebral blood flow dysregulation in Alzheimer's phenotype
PNAS 2007 104: 823-828; published online before print January 10 2007, 10.1073/pnas.0608251104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Qinghong Zhang, Su-Yan Wang, Capucine Fleuriel, Dominique Leprince, Jonathan V. Rocheleau, David W. Piston, and Richard H. Goodman

Metabolic regulation of SIRT1 transcription via a HIC1:CtBP corepressor complex
PNAS 2007 104: 829-833; published online before print January 9 2007, 10.1073/pnas.0610590104 [Abstract] [Full Text] [Figures Only] [PDF]  

Developmental Biology

Caroline Schmitz, Parag Kinge, and Harald Hutter

Axon guidance genes identified in a large-scale RNAi screen using the RNAi-hypersensitive Caenorhabditis elegans strain nre-1(hd20) lin-15b(hd126)
PNAS 2007 104: 834-839; published online before print January 9 2007, 10.1073/pnas.0510527104 [Abstract] [Full Text] [Figures Only] [PDF]  

John E. Pimanda, Ian J. Donaldson, Marella F. T. R. de Bruijn, Sarah Kinston, Kathy Knezevic, Liz Huckle, Sandie Piltz, Josette-Renée Landry, Anthony R. Green, David Tannahill, and Berthold Göttgens

The SCL transcriptional network and BMP signaling pathway interact to regulate RUNX1 activity
PNAS 2007 104: 840-845; published online before print January 9 2007, 10.1073/pnas.0607196104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Jun K. Takeuchi, Heiko Lickert, Brent W. Bisgrove, Xin Sun, Masamichi Yamamoto, Kallayanee Chawengsaksophak, Hiroshi Hamada, H. Joseph Yost, Janet Rossant, and Benoit G. Bruneau

Baf60c is a nuclear Notch signaling component required for the establishment of left–right asymmetry
PNAS 2007 104: 846-851; published online before print January 8 2007, 10.1073/pnas.0608118104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figure]  

Yong Yang, Yinyan Sun, Xin Luo, Yuxia Zhang, Yaoyao Chen, E. Tian, Robyn Lints, and Hong Zhang

Polycomb-like genes are necessary for specification of dopaminergic and serotonergic neurons in Caenorhabditis elegans
PNAS 2007 104: 852-857; published online before print January 10 2007, 10.1073/pnas.0610261104 [Abstract] [Full Text] [Figures Only] [PDF]  

Ecology

Gabriele Gerlach, Jelle Atema, Michael J. Kingsford, Kerry P. Black, and Vanessa Miller-Sims

Smelling home can prevent dispersal of reef fish larvae
PNAS 2007 104: 858-863; published online before print January 9 2007, 10.1073/pnas.0606777104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Robert John, James W. Dalling, Kyle E. Harms, Joseph B. Yavitt, Robert F. Stallard, Matthew Mirabello, Stephen P. Hubbell, Renato Valencia, Hugo Navarrete, Martha Vallejo, and Robin B. Foster

Soil nutrients influence spatial distributions of tropical tree species
PNAS 2007 104: 864-869; published online before print January 10 2007, 10.1073/pnas.0604666104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Evolution

Jasper A. Vrugt and Bruce A. Robinson Improved evolutionary optimization from genetically adaptive multimethod search PNAS 2007 104: 708-711; published online before print January 10 2007, 10.1073/pnas.0610471104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Tal Dagan and William Martin

Ancestral genome sizes specify the minimum rate of lateral gene transfer during prokaryote evolution
PNAS 2007 104: 870-875; published online before print January 9 2007, 10.1073/pnas.0606318104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Joao B. Xavier and Kevin R. Foster From the Cover: Cooperation and conflict in microbial biofilms PNAS 2007 104: 876-881; published online before print January 8 2007, 10.1073/pnas.0607651104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]

Degen Zhuo, Richard Madden, Sherif Abou Elela, and Benoit Chabot

Modern origin of numerous alternatively spliced human introns from tandem arrays
PNAS 2007 104: 882-886; published online before print January 8 2007, 10.1073/pnas.0604777104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Kim Roelants, David J. Gower, Mark Wilkinson, Simon P. Loader, S. D. Biju, Karen Guillaume, Linde Moriau, and Franky Bossuyt

Global patterns of diversification in the history of modern amphibians
PNAS 2007 104: 887-892; published online before print January 9 2007, 10.1073/pnas.0608378104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Genetics

Blerta Xhemalce, Eva Madi Riising, Peter Baumann, Anne Dejean, Benoît Arcangioli, and Jacob-S. Seeler

Role of SUMO in the dynamics of telomere maintenance in fission yeast
PNAS 2007 104: 893-898; published online before print January 5 2007, 10.1073/pnas.0605442104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Thanat Chookajorn, Ron Dzikowski, Matthias Frank, Felomena Li, Alisha Z. Jiwani, Daniel L. Hartl, and Kirk W. Deitsch Epigenetic memory at malaria virulence genes PNAS 2007 104: 899-902; published online before print January 5 2007, 10.1073/pnas.0609084103 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Immunology

Abbas Hawwari and Michael S. Krangel

Role for rearranged variable gene segments in directing secondary T cell receptor recombination
PNAS 2007 104: 903-907; published online before print January 8 2007, 10.1073/pnas.0608248104 [Abstract] [Full Text] [Figures Only] [PDF]  

Camille Lobry, Tatiana Lopez, Alain Israël, and Robert Weil

Negative feedback loop in T cell activation through IB kinase-induced phosphorylation and degradation of Bcl10
PNAS 2007 104: 908-913; published online before print January 9 2007, 10.1073/pnas.0606982104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

Hai-Chon Lee and Steven F. Ziegler

Inducible expression of the proallergic cytokine thymic stromal lymphopoietin in airway epithelial cells is controlled by NFB
PNAS 2007 104: 914-919; published online before print January 9 2007, 10.1073/pnas.0607305104 [Abstract] [Full Text] [Figures Only] [PDF]  

Francesca Odoardi, Naoto Kawakami, Zhaoxia Li, Chiara Cordiglieri, Kristina Streyl, Mikhail Nosov, Wolfgang E. F. Klinkert, Joachim W. Ellwart, Jan Bauer, Hans Lassmann, Hartmut Wekerle, and Alexander Flügel

Instant effect of soluble antigen on effector T cells in peripheral immune organs during immunotherapy of autoimmune encephalomyelitis
PNAS 2007 104: 920-925; published online before print January 9 2007, 10.1073/pnas.0608383104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Miguel A. de la Fuente, Yoji Sasahara, Marco Calamito, Inés M. Antón, Abdallah Elkhal, Maria D. Gallego, Koduru Suresh, Katherine Siminovitch, Hans D. Ochs, Kenneth C. Anderson, Fred S. Rosen, Raif S. Geha, and Narayanaswamy Ramesh

WIP is a chaperone for Wiskott–Aldrich syndrome protein (WASP)
PNAS 2007 104: 926-931; published online before print January 9 2007, 10.1073/pnas.0610275104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

Medical Sciences

Dmitri Simberg, Tasmia Duza, Ji Ho Park, Markus Essler, Jan Pilch, Lianglin Zhang, Austin M. Derfus, Meng Yang, Robert M. Hoffman, Sangeeta Bhatia, Michael J. Sailor, and Erkki Ruoslahti

Biomimetic amplification of nanoparticle homing to tumors
PNAS 2007 104: 932-936; published online before print January 10 2007, 10.1073/pnas.0610298104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Lotte Bjerre Knudsen, Dan Kiel, Min Teng, Carsten Behrens, Dilip Bhumralkar, János T. Kodra, Jens J. Holst, Claus B. Jeppesen, Michael D. Johnson, Johannes Cornelis de Jong, Anker Steen Jorgensen, Tim Kercher, Jarek Kostrowicki, Peter Madsen, Preben H. Olesen, Jacob S. Petersen, Fritz Poulsen, Ulla G. Sidelmann, Jeppe Sturis, Larry Truesdale, John May, and Jesper Lau From the Cover: Small-molecule agonists for the glucagon-like peptide 1 receptor PNAS 2007 104: 937-942; published online before print January 9 2007, 10.1073/pnas.0605701104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]   See Commentary on page 689

Desu Chen, Jiayu Liao, Na Li, Caihong Zhou, Qing Liu, Guangxing Wang, Rui Zhang, Song Zhang, Lilin Lin, Kaixian Chen, Xin Xie, Fajun Nan, Andrew A. Young, and Ming-Wei Wang From the Cover: A nonpeptidic agonist of glucagon-like peptide 1 receptors with efficacy in diabetic db/db mice PNAS 2007 104: 943-948; published online before print January 9 2007, 10.1073/pnas.0610173104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE   See Commentary on page 689

Sophie Bensing, Sergueï O. Fetissov, Jan Mulder, Jaakko Perheentupa, Jan Gustafsson, Eystein S. Husebye, Mikael Oscarson, Olov Ekwall, Patricia A. Crock, Tomas Hökfelt, Anna-Lena Hulting, and Olle Kämpe

Pituitary autoantibodies in autoimmune polyendocrine syndrome type 1
PNAS 2007 104: 949-954; published online before print January 10 2007, 10.1073/pnas.0610070104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figure]  

Clemens R. Scherzer, Aron C. Eklund, Lee J. Morse, Zhixiang Liao, Joseph J. Locascio, Daniel Fefer, Michael A. Schwarzschild, Michael G. Schlossmacher, Michael A. Hauser, Jeffery M. Vance, Lewis R. Sudarsky, David G. Standaert, John H. Growdon, Roderick V. Jensen, and Steven R. Gullans Molecular markers of early Parkinson's disease based on gene expression in blood PNAS 2007 104: 955-960; published online before print January 10 2007, 10.1073/pnas.0610204104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Vardan Amirbekian, Michael J. Lipinski, Karen C. Briley-Saebo, Smbat Amirbekian, Juan Gilberto S. Aguinaldo, David B. Weinreb, Esad Vucic, Juan C. Frias, Fabien Hyafil, Venkatesh Mani, Edward A. Fisher, and Zahi A. Fayad Detecting and assessing macrophages in vivo to evaluate atherosclerosis noninvasively using molecular MRI PNAS 2007 104: 961-966; published online before print January 10 2007, 10.1073/pnas.0606281104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Text] OPEN ACCESS ARTICLE

Michael I. Dorrell, Edith Aguilar, Lea Scheppke, Faith H. Barnett, and Martin Friedlander Combination angiostatic therapy completely inhibits ocular and tumor angiogenesis PNAS 2007 104: 967-972; published online before print January 8 2007, 10.1073/pnas.0607542104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

M. E. Prince, R. Sivanandan, A. Kaczorowski, G. T. Wolf, M. J. Kaplan, P. Dalerba, I. L. Weissman, M. F. Clarke, and L. E. Ailles

Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma
PNAS 2007 104: 973-978; published online before print January 8 2007, 10.1073/pnas.0610117104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Fredrik Bäckhed, Jill K. Manchester, Clay F. Semenkovich, and Jeffrey I. Gordon From the Cover: Mechanisms underlying the resistance to diet-induced obesity in germ-free mice PNAS 2007 104: 979-984; published online before print January 8 2007, 10.1073/pnas.0605374104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Ying Huang, Huiying Yang, Brian B. Borg, Xiaowen Su, Shannon L. Rhodes, Kai Yang, Xiaomei Tong, George Tang, Charles D. Howell, Hugo R. Rosen, Chloe L. Thio, David L. Thomas, Harvey J. Alter, Ronda K. Sapp, and T. Jake Liang

A functional SNP of interferon- gene is important for interferon--induced and spontaneous recovery from hepatitis C virus infection
PNAS 2007 104: 985-990; published online before print January 10 2007, 10.1073/pnas.0609954104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Tables]  

Alessia Angelin, Tania Tiepolo, Patrizia Sabatelli, Paolo Grumati, Natascha Bergamin, Cristina Golfieri, Elisabetta Mattioli, Francesca Gualandi, Alessandra Ferlini, Luciano Merlini, Nadir M. Maraldi, Paolo Bonaldo, and Paolo Bernardi

Mitochondrial dysfunction in the pathogenesis of Ullrich congenital muscular dystrophy and prospective therapy with cyclosporins
PNAS 2007 104: 991-996; published online before print January 10 2007, 10.1073/pnas.0610270104 [Abstract] [Full Text] [Figures Only] [PDF]  

Microbiology

Lindsay G. Stevenson, Kvido Strisovsky, Katy M. Clemmer, Shantanu Bhatt, Matthew Freeman, and Philip N. Rather

Rhomboid protease AarA mediates quorum-sensing in Providencia stuartii by activating TatA of the twin-arginine translocase
PNAS 2007 104: 1003-1008; published online before print January 10 2007, 10.1073/pnas.0608140104 [Abstract] [Full Text] [Figures Only] [PDF]  

Larry A. Gallagher, Elizabeth Ramage, Michael A. Jacobs, Rajinder Kaul, Mitchell Brittnacher, and Colin Manoil

A comprehensive transposon mutant library of Francisella novicida, a bioweapon surrogate
PNAS 2007 104: 1009-1014; published online before print January 10 2007, 10.1073/pnas.0606713104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Christine Goffinet, Ina Allespach, and Oliver T. Keppler

HIV-susceptible transgenic rats allow rapid preclinical testing of antiviral compounds targeting virus entry or reverse transcription
PNAS 2007 104: 1015-1020; published online before print January 5 2007, 10.1073/pnas.0607414104 [Abstract] [Full Text] [Figures Only] [PDF]  

David G. Longstaff, Ross C. Larue, Joseph E. Faust, Anirban Mahapatra, Liwen Zhang, Kari B. Green-Church, and Joseph A. Krzycki

A natural genetic code expansion cassette enables transmissible biosynthesis and genetic encoding of pyrrolysine
PNAS 2007 104: 1021-1026; published online before print January 4 2007, 10.1073/pnas.0610294104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Neuroscience

Andrea Lorincz, Balázs Rózsa, Gergely Katona, E. Sylvester Vizi, and Gábor Tamás

Differential distribution of NCX1 contributes to spine–dendrite compartmentalization in CA1 pyramidal cells
PNAS 2007 104: 1033-1038; published online before print January 10 2007, 10.1073/pnas.0605412104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Alexander T. Chesler, Dong-Jing Zou, Claire E. Le Pichon, Zita A. Peterlin, Glennis A. Matthews, Xin Pei, Michael C. Miller, and Stuart Firestein

A G protein/cAMP signal cascade is required for axonal convergence into olfactory glomeruli
PNAS 2007 104: 1039-1044; published online before print January 10 2007, 10.1073/pnas.0609215104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

G. V. Drivonikou, P. Kay, T. Regier, R. B. Ivry, A. L. Gilbert, A. Franklin, and I. R. L. Davies

Further evidence that Whorfian effects are stronger in the right visual field than the left
PNAS 2007 104: 1097-1102; published online before print January 9 2007, 10.1073/pnas.0610132104 [Abstract] [Full Text] [Figures Only] [PDF]  

Pharmacology

Sharon M. Blättler, Franck Rencurel, Michel R. Kaufmann, and Urs A. Meyer

In the regulation of cytochrome P450 genes, phenobarbital targets LKB1 for necessary activation of AMP-activated protein kinase
PNAS 2007 104: 1045-1050; published online before print January 9 2007, 10.1073/pnas.0610216104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Physiology

Van M. Savage and Geoffrey B. West

A quantitative, theoretical framework for understanding mammalian sleep
PNAS 2007 104: 1051-1056; published online before print January 10 2007, 10.1073/pnas.0610080104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Table]  

Catherine E. Amara, Eric G. Shankland, Sharon A. Jubrias, David J. Marcinek, Martin J. Kushmerick, and Kevin E. Conley Mild mitochondrial uncoupling impacts cellular aging in human muscles in vivo PNAS 2007 104: 1057-1062; published online before print January 10 2007, 10.1073/pnas.0610131104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

David A. Hill, Ajay D. Pillai, Fatima Nawaz, Karen Hayton, Lanxuan Doan, Godfrey Lisk, and Sanjay A. Desai

A blasticidin S-resistant Plasmodium falciparum mutant with a defective plasmodial surface anion channel
PNAS 2007 104: 1063-1068; published online before print January 9 2007, 10.1073/pnas.0610353104 [Abstract] [Full Text] [Figures Only] [PDF]  

Plant Biology

Uwe Schumann, Jakob Prestele, Henriette O'Geen, Robert Brueggeman, Gerhard Wanner, and Christine Gietl

Requirement of the C₃HC₄ zinc RING finger of the Arabidopsis PEX10 for photorespiration and leaf peroxisome contact with chloroplasts
PNAS 2007 104: 1069-1074; published online before print January 10 2007, 10.1073/pnas.0610402104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Text]  

William Truman, Mark H. Bennett, Ines Kubigsteltig, Colin Turnbull, and Murray Grant

Arabidopsis systemic immunity uses conserved defense signaling pathways and is mediated by jasmonates
PNAS 2007 104: 1075-1080; published online before print January 10 2007, 10.1073/pnas.0605423104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Clinton J. Whipple, Michael J. Zanis, Elizabeth A. Kellogg, and Robert J. Schmidt

Conservation of B class gene expression in the second whorl of a basal grass and outgroups links the origin of lodicules and petals
PNAS 2007 104: 1081-1086; published online before print January 8 2007, 10.1073/pnas.0606434104 [Abstract] [Full Text] [Figures Only] [PDF]  

CORRECTIONS

Correction for Shoshani et al., A proboscidean from the late Oligocene of Eritrea, a ‘missing link’ between early Elephantiformes and Elephantimorpha, and biogeographic implications [Full Text] [PDF]