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THIS WEEK IN PNAS

In This Issue
PNAS 2007 104: 16721-16722. [Full Text] [PDF]  

COMMENTARIES

Esther Krook-Magnuson and Molly M. Huntsman

The transience of interneuron circuit diversity just "sped" up
PNAS 2007 104: 16723-16724; published online on October 15, 2007, 10.1073/pnas.0708149104 [Extract] [Full Text] [Figures Only] [PDF]  
See companion article on page 14831 in issue 37 of volume 104

Jonathan L. Haines, Kylee M. Spencer, and Margaret A. Pericak-Vance

Bringing the genetics of macular degeneration into focus
PNAS 2007 104: 16725-16726; published online on October 16, 2007, 10.1073/pnas.0708151104 [Extract] [Full Text] [Figures Only] [PDF]  
See companion article on page 16227 in issue 41 of volume 104

C. Robertson McClung

The cyanobacterial circadian clock is based on the intrinsic ATPase activity of KaiC
PNAS 2007 104: 16727-16728; published online on October 16, 2007, 10.1073/pnas.0708757104 [Extract] [Full Text] [Figures Only] [PDF]  
See companion article on page 16377 in issue 41 of volume 104

Stephen O. Duke

The emergence of grass root chemical ecology
PNAS 2007 104: 16729-16730; published online on October 17, 2007, 10.1073/pnas.0707837104 [Extract] [Full Text] [PDF]  
See companion article on page 16964

SPECIAL FEATURE

Introduction

Robert W. Kates and Partha Dasgupta

Poverty and Hunger Special Feature: African poverty: A grand challenge for sustainability science
PNAS 2007 104: 16747-16750; published online on October 17, 2007, 10.1073/pnas.0708566104 [Extract] [Full Text] [PDF]  

Perspectives

Goran Hyden

Poverty and Hunger Special Feature: Governance and poverty reduction in Africa
PNAS 2007 104: 16751-16756; published online on October 17, 2007, 10.1073/pnas.0700696104 [Abstract] [Full Text] [PDF]  

Research Articles

Shaohua Chen and Martin Ravallion

Poverty and Hunger Special Feature: Absolute poverty measures for the developing world, 1981–2004
PNAS 2007 104: 16757-16762; published online on October 17, 2007, 10.1073/pnas.0702930104 [Abstract] [Full Text] [Figures Only] [PDF]  

Paul Collier

Poverty And Hunger Special Feature: Poverty reduction in Africa
PNAS 2007 104: 16763-16768; published online on October 17, 2007, 10.1073/pnas.0611702104 [Abstract] [Full Text] [PDF]  

Paul O. Okwi, Godfrey Ndeng'e, Patti Kristjanson, Mike Arunga, An Notenbaert, Abisalom Omolo, Norbert Henninger, Todd Benson, Patrick Kariuki, and John Owuor

From the Cover: Poverty And Hunger Special Feature: Spatial determinants of poverty in rural Kenya
PNAS 2007 104: 16769-16774; published online on October 17, 2007, 10.1073/pnas.0611107104 [Abstract] [Full Text] [PDF] [Supporting Information]  

Pedro Sanchez, Cheryl Palm, Jeffrey Sachs, Glenn Denning, Rafael Flor, Rebbie Harawa, Bashir Jama, Tsegazeab Kiflemariam, Bronwen Konecky, Raffaela Kozar, Eliud Lelerai, Alia Malik, Vijay Modi, Patrick Mutuo, Amadou Niang, Herine Okoth, Frank Place, Sonia Ehrlich Sachs, Amir Said, David Siriri, Awash Teklehaimanot, Karen Wang, Justine Wangila, and Colleen Zamba

Poverty And Hunger Special Feature: The African Millennium Villages
PNAS 2007 104: 16775-16780; published online on October 17, 2007, 10.1073/pnas.0700423104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Akin L. Mabogunje

Poverty And Hunger Special Feature: Tackling the African "poverty trap": The Ijebu-Ode experiment
PNAS 2007 104: 16781-16786; published online on October 17, 2007, 10.1073/pnas.0704765104 [Abstract] [Full Text] [PDF]  

PHYSICAL SCIENCES

Applied Mathematics

Maga Rowicka, Andrzej Kudlicki, Benjamin P. Tu, and Zbyszek Otwinowski

High-resolution timing of cell cycle-regulated gene expression
PNAS 2007 104: 16892-16897; published online on September 7, 2007, 10.1073/pnas.0706022104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Chemistry

Liqin Qiu, Mahavir Prashad, Bin Hu, Kapa Prasad, Oljan Repic, Thomas J. Blacklock, Fuk Yee Kwong, Stanton H. L. Kok, Hang Wai Lee, and Albert S. C. Chan

Enantioselective hydrogenation of -aminomethylacrylates containing a free NH group for the synthesis of -amino acid derivatives
PNAS 2007 104: 16787-16792; published online on October 17, 2007, 10.1073/pnas.0704461104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Text]  

Jeremy M. Baskin, Jennifer A. Prescher, Scott T. Laughlin, Nicholas J. Agard, Pamela V. Chang, Isaac A. Miller, Anderson Lo, Julian A. Codelli, and Carolyn R. Bertozzi From the Cover: Copper-free click chemistry for dynamic in vivo imaging PNAS 2007 104: 16793-16797; published online on October 17, 2007, 10.1073/pnas.0707090104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]

Sonjae Wallace, Lulu Huang, Lou Massa, Uday Mukhopadhyay, Ivan Bernal, and Jerome Karle

The structures of cyclic dihydronium cations
PNAS 2007 104: 16798-16803; published online on October 17, 2007, 10.1073/pnas.0708249104 [Abstract] [Full Text] [Figures Only] [PDF]  

Jennifer J. McManus, Aleksey Lomakin, Olutayo Ogun, Ajay Pande, Markus Basan, Jayanti Pande, and George B. Benedek From the Cover: Altered phase diagram due to a single point mutation in human D-crystallin PNAS 2007 104: 16856-16861; published online on October 8, 2007, 10.1073/pnas.0707412104 [Abstract] [Full Text] [Figures Only] [PDF]   See Commentary on page 18877

Frank Müh, Mohamed El-Amine Madjet, Julia Adolphs, Ayjamal Abdurahman, Björn Rabenstein, Hiroshi Ishikita, Ernst-Walter Knapp, and Thomas Renger

-Helices direct excitation energy flow in the Fenna–Matthews–Olson protein
PNAS 2007 104: 16862-16867; published online on October 11, 2007, 10.1073/pnas.0708222104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Geophysics

Hansjörg Seybold, José S. Andrade, Jr., and Hans J. Herrmann

Modeling river delta formation
PNAS 2007 104: 16804-16809; published online on October 16, 2007, 10.1073/pnas.0705265104 [Abstract] [Full Text] [Figures Only] [PDF]  

SOCIAL SCIENCES

Anthropology

James K. Rilling, Sarah K. Barks, Lisa A. Parr, Todd M. Preuss, Tracy L. Faber, Giuseppe Pagnoni, J. Douglas Bremner, and John R. Votaw

A comparison of resting-state brain activity in humans and chimpanzees
PNAS 2007 104: 17146-17151; published online on October 16, 2007, 10.1073/pnas.0705132104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Economic Sciences

Shaohua Chen and Martin Ravallion

Poverty and Hunger Special Feature: Absolute poverty measures for the developing world, 1981–2004
PNAS 2007 104: 16757-16762; published online on October 17, 2007, 10.1073/pnas.0702930104 [Abstract] [Full Text] [Figures Only] [PDF]  

Paul Collier

Poverty And Hunger Special Feature: Poverty reduction in Africa
PNAS 2007 104: 16763-16768; published online on October 17, 2007, 10.1073/pnas.0611702104 [Abstract] [Full Text] [PDF]  

Environmental Sciences

Paul O. Okwi, Godfrey Ndeng'e, Patti Kristjanson, Mike Arunga, An Notenbaert, Abisalom Omolo, Norbert Henninger, Todd Benson, Patrick Kariuki, and John Owuor

From the Cover: Poverty And Hunger Special Feature: Spatial determinants of poverty in rural Kenya
PNAS 2007 104: 16769-16774; published online on October 17, 2007, 10.1073/pnas.0611107104 [Abstract] [Full Text] [PDF] [Supporting Information]  

Psychology

Yi-Yuan Tang, Yinghua Ma, Junhong Wang, Yaxin Fan, Shigang Feng, Qilin Lu, Qingbao Yu, Danni Sui, Mary K. Rothbart, Ming Fan, and Michael I. Posner

Short-term meditation training improves attention and self-regulation
PNAS 2007 104: 17152-17156; published online on October 11, 2007, 10.1073/pnas.0707678104 [Abstract] [Full Text] [Figures Only] [PDF]  

Chun-Yu Tse, Chia-Lin Lee, Jason Sullivan, Susan M. Garnsey, Gary S. Dell, Monica Fabiani, and Gabriele Gratton Imaging cortical dynamics of language processing with the event-related optical signal PNAS 2007 104: 17157-17162; published online on October 17, 2007, 10.1073/pnas.0707901104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Sustainability Science

Pedro Sanchez, Cheryl Palm, Jeffrey Sachs, Glenn Denning, Rafael Flor, Rebbie Harawa, Bashir Jama, Tsegazeab Kiflemariam, Bronwen Konecky, Raffaela Kozar, Eliud Lelerai, Alia Malik, Vijay Modi, Patrick Mutuo, Amadou Niang, Herine Okoth, Frank Place, Sonia Ehrlich Sachs, Amir Said, David Siriri, Awash Teklehaimanot, Karen Wang, Justine Wangila, and Colleen Zamba

Poverty And Hunger Special Feature: The African Millennium Villages
PNAS 2007 104: 16775-16780; published online on October 17, 2007, 10.1073/pnas.0700423104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Akin L. Mabogunje

Poverty And Hunger Special Feature: Tackling the African "poverty trap": The Ijebu-Ode experiment
PNAS 2007 104: 16781-16786; published online on October 17, 2007, 10.1073/pnas.0704765104 [Abstract] [Full Text] [PDF]  

BIOLOGICAL SCIENCES

Applied Biological Sciences

Sharon L. Doty, C. Andrew James, Allison L. Moore, Azra Vajzovic, Glenda L. Singleton, Caiping Ma, Zareen Khan, Gang Xin, Jun Won Kang, Jin Young Park, Richard Meilan, Steven H. Strauss, Jasmine Wilkerson, Federico Farin, and Stuart E. Strand

Enhanced phytoremediation of volatile environmental pollutants with transgenic trees
PNAS 2007 104: 16816-16821; published online on October 16, 2007, 10.1073/pnas.0703276104 [Abstract] [Full Text] [Figures Only] [PDF]  

Rosamond G. Jackson, Elizabeth L. Rylott, Diane Fournier, Jalal Hawari, and Neil C. Bruce

Exploring the biochemical properties and remediation applications of the unusual explosive-degrading P450 system XplA/B
PNAS 2007 104: 16822-16827; published online on October 16, 2007, 10.1073/pnas.0705110104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figure]  

Biochemistry

Brett D. Welch, Andrew P. VanDemark, Annie Heroux, Christopher P. Hill, and Michael S. Kay

Potent D-peptide inhibitors of HIV-1 entry
PNAS 2007 104: 16828-16833; published online on October 17, 2007, 10.1073/pnas.0708109104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Jun Zou, Jasna Marjanovic, Marina V. Kisseleva, Monita Wilson, and Philip W. Majerus

Type I phosphatidylinositol-4,5-bisphosphate 4-phosphatase regulates stress-induced apoptosis
PNAS 2007 104: 16834-16839; published online on October 16, 2007, 10.1073/pnas.0708189104 [Abstract] [Full Text] [Figures Only] [PDF]  

Andrei Korostelev, Sergei Trakhanov, Haruichi Asahara, Martin Laurberg, Laura Lancaster, and Harry F. Noller

Interactions and dynamics of the Shine–Dalgarno helix in the 70S ribosome
PNAS 2007 104: 16840-16843; published online on October 16, 2007, 10.1073/pnas.0707850104 [Abstract] [Full Text] [Figures Only] [PDF]  

Hong-Wei Wang, Jianjun Wang, Fang Ding, Kevin Callahan, Matthew A. Bratkowski, J. Scott Butler, Eva Nogales, and Ailong Ke

Architecture of the yeast Rrp44–exosome complex suggests routes of RNA recruitment for 3' end processing
PNAS 2007 104: 16844-16849; published online on October 17, 2007, 10.1073/pnas.0705526104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Alla V. Tsytsykova, Ricardo Rajsbaum, James V. Falvo, Filipa Ligeiro, Simon R. Neely, and Anne E. Goldfeld

Activation-dependent intrachromosomal interactions formed by the TNF gene promoter and two distal enhancers
PNAS 2007 104: 16850-16855; published online on October 16, 2007, 10.1073/pnas.0708210104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Benjamin P. Tu, Rachel E. Mohler, Jessica C. Liu, Kenneth M. Dombek, Elton T. Young, Robert E. Synovec, and Steven L. McKnight

Cyclic changes in metabolic state during the life of a yeast cell
PNAS 2007 104: 16886-16891; published online on October 16, 2007, 10.1073/pnas.0708365104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Biophysics

Frank Müh, Mohamed El-Amine Madjet, Julia Adolphs, Ayjamal Abdurahman, Björn Rabenstein, Hiroshi Ishikita, Ernst-Walter Knapp, and Thomas Renger

-Helices direct excitation energy flow in the Fenna–Matthews–Olson protein
PNAS 2007 104: 16862-16867; published online on October 11, 2007, 10.1073/pnas.0708222104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Derek N. Fuller, Dorian M. Raymer, Vishal I. Kottadiel, Venigalla B. Rao, and Douglas E. Smith

Single phage T4 DNA packaging motors exhibit large force generation, high velocity, and dynamic variability
PNAS 2007 104: 16868-16873; published online on October 17, 2007, 10.1073/pnas.0704008104 [Abstract] [Full Text] [Figures Only] [PDF]  

Qinghua Wang, Xia Tian, Xiaorui Chen, and Jianpeng Ma

Structural basis for receptor specificity of influenza B virus hemagglutinin
PNAS 2007 104: 16874-16879; published online on October 17, 2007, 10.1073/pnas.0708363104 [Abstract] [Full Text] [Figures Only] [PDF]  

Jana Khandogin and Charles L. Brooks, III

Linking folding with aggregation in Alzheimer's -amyloid peptides
PNAS 2007 104: 16880-16885; published online on October 17, 2007, 10.1073/pnas.0703832104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Cell Biology

Benjamin P. Tu, Rachel E. Mohler, Jessica C. Liu, Kenneth M. Dombek, Elton T. Young, Robert E. Synovec, and Steven L. McKnight

Cyclic changes in metabolic state during the life of a yeast cell
PNAS 2007 104: 16886-16891; published online on October 16, 2007, 10.1073/pnas.0708365104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Maga Rowicka, Andrzej Kudlicki, Benjamin P. Tu, and Zbyszek Otwinowski

High-resolution timing of cell cycle-regulated gene expression
PNAS 2007 104: 16892-16897; published online on September 7, 2007, 10.1073/pnas.0706022104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Lisa A. Ridnour, Alisha N. Windhausen, Jeffrey S. Isenberg, Nolan Yeung, Douglas D. Thomas, Michael P. Vitek, David D. Roberts, and David A. Wink Nitric oxide regulates matrix metalloproteinase-9 activity by guanylyl-cyclase-dependent and -independent pathways PNAS 2007 104: 16898-16903; published online on October 17, 2007, 10.1073/pnas.0702761104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures] OPEN ACCESS ARTICLE

Fangtian Huang, Lai Kuan Goh, and Alexander Sorkin

EGF receptor ubiquitination is not necessary for its internalization
PNAS 2007 104: 16904-16909; published online on October 16, 2007, 10.1073/pnas.0707416104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Table]  

Grant S. Stewart, Tatjana Stankovic, Philip J. Byrd, Thomas Wechsler, Edward S. Miller, Aarn Huissoon, Mark T. Drayson, Stephen C. West, Stephen J. Elledge, and A. Malcolm R. Taylor RIDDLE immunodeficiency syndrome is linked to defects in 53BP1-mediated DNA damage signaling PNAS 2007 104: 16910-16915; published online on October 16, 2007, 10.1073/pnas.0708408104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

E. Stefan, S. Aquin, N. Berger, C. R. Landry, B. Nyfeler, M. Bouvier, and S. W. Michnick

Quantification of dynamic protein complexes using Renilla luciferase fragment complementation applied to protein kinase A activities in vivo
PNAS 2007 104: 16916-16921; published online on October 17, 2007, 10.1073/pnas.0704257104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Mattias Sjöström, Karin Stenström, Kristina Eneling, Jean Zwiller, Adrian I. Katz, Hiroshi Takemori, and Alejandro M. Bertorello

SIK1 is part of a cell sodium-sensing network that regulates active sodium transport through a calcium-dependent process
PNAS 2007 104: 16922-16927; published online on October 15, 2007, 10.1073/pnas.0706838104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Julien Heuvingh, Michel Franco, Philippe Chavrier, and Cécile Sykes

ARF1-mediated actin polymerization produces movement of artificial vesicles
PNAS 2007 104: 16928-16933; published online on October 17, 2007, 10.1073/pnas.0704749104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Harry Scherthan, Hailin Wang, Caroline Adelfalk, Eric J. White, Carrie Cowan, W. Zacheus Cande, and David B. Kaback Chromosome mobility during meiotic prophase in Saccharomyces cerevisiae PNAS 2007 104: 16934-16939; published online on October 15, 2007, 10.1073/pnas.0704860104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Jeffrey T. Irelan, Thomas J. Murphy, Paul D. DeJesus, Hsiangling Teo, DingYue Xu, Maria A. Gomez-Ferreria, Yingyao Zhou, Loren J. Miraglia, Daniel R. Rines, Inder M. Verma, David J. Sharp, Vinay Tergaonkar, and Sumit K. Chanda

A role for IB kinase 2 in bipolar spindle assembly
PNAS 2007 104: 16940-16945; published online on October 15, 2007, 10.1073/pnas.0706493104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Developmental Biology

Samir Merabet, Mehdi Saadaoui, Nagraj Sambrani, Bruno Hudry, Jacques Pradel, Markus Affolter, and Yacine Graba

A unique Extradenticle recruitment mode in the Drosophila Hox protein Ultrabithorax
PNAS 2007 104: 16946-16951; published online on October 17, 2007, 10.1073/pnas.0705832104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

Bernhard Schiedlmeier, Ana Cristina Santos, Ana Ribeiro, Natalia Moncaut, Dietrich Lesinski, Herbert Auer, Karl Kornacker, Wolfram Ostertag, Christopher Baum, Moises Mallo, and Hannes Klump

HOXB4's road map to stem cell expansion
PNAS 2007 104: 16952-16957; published online on October 16, 2007, 10.1073/pnas.0703082104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Hiromi Kurokawa, Daisuke Saito, Shuhei Nakamura, Yuko Katoh-Fukui, Kohei Ohta, Takashi Baba, Ken-ichiro Morohashi, and Minoru Tanaka

Germ cells are essential for sexual dimorphism in the medaka gonad
PNAS 2007 104: 16958-16963; published online on October 16, 2007, 10.1073/pnas.0609932104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Ecology

Philippe Vandenkoornhuyse, Stéphane Mahé, Philip Ineson, Phil Staddon, Nick Ostle, Jean-Bernard Cliquet, André-Jean Francez, Alastair H. Fitter, and J. Peter W. Young

Active root-inhabiting microbes identified by rapid incorporation of plant-derived carbon into RNA
PNAS 2007 104: 16970-16975; published online on October 15, 2007, 10.1073/pnas.0705902104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Eldon S. Eveleigh, Kevin S. McCann, Peter C. McCarthy, Steven J. Pollock, Christopher J. Lucarotti, Benoit Morin, George A. McDougall, Douglas B. Strongman, John T. Huber, James Umbanhowar, and Lucas D. B. Faria Fluctuations in density of an outbreak species drive diversity cascades in food webs PNAS 2007 104: 16976-16981; published online on October 15, 2007, 10.1073/pnas.0704301104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Evolution

Johannes M. H. Knops, Walter D. Koenig, and William J. Carmen

Negative correlation does not imply a tradeoff between growth and reproduction in California oaks
PNAS 2007 104: 16982-16985; published online on October 16, 2007, 10.1073/pnas.0704251104 [Abstract] [Full Text] [Figures Only] [PDF]  

Nora Scarcelli, James M. Cheverud, Barbara A. Schaal, and Paula X. Kover

Antagonistic pleiotropic effects reduce the potential adaptive value of the FRIGIDA locus
PNAS 2007 104: 16986-16991; published online on October 16, 2007, 10.1073/pnas.0708209104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Jane Charlesworth and Adam Eyre-Walker

The other side of the nearly neutral theory, evidence of slightly advantageous back-mutations
PNAS 2007 104: 16992-16997; published online on October 16, 2007, 10.1073/pnas.0705456104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Ron Milo, Jennifer H. Hou, Michael Springer, Michael P. Brenner, and Marc W. Kirschner The relationship between evolutionary and physiological variation in hemoglobin PNAS 2007 104: 16998-17003; published online on October 17, 2007, 10.1073/pnas.0707673104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Ulfar Bergthorsson, Dan I. Andersson, and John R. Roth

Ohno's dilemma: Evolution of new genes under continuous selection
PNAS 2007 104: 17004-17009; published online on October 17, 2007, 10.1073/pnas.0707158104 [Abstract] [Full Text] [Figures Only] [PDF]  

Genetics

Laura Narciso, Paola Fortini, Deborah Pajalunga, Annapaola Franchitto, Pingfang Liu, Paolo Degan, Mathilde Frechet, Bruce Demple, Marco Crescenzi, and Eugenia Dogliotti

Terminally differentiated muscle cells are defective in base excision DNA repair and hypersensitive to oxygen injury
PNAS 2007 104: 17010-17015; published online on October 16, 2007, 10.1073/pnas.0701743104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Iris Eisenberg, Alal Eran, Ichizo Nishino, Maurizio Moggio, Costanza Lamperti, Anthony A. Amato, Hart G. Lidov, Peter B. Kang, Kathryn N. North, Stella Mitrani-Rosenbaum, Kevin M. Flanigan, Lori A. Neely, Duncan Whitney, Alan H. Beggs, Isaac S. Kohane, and Louis M. Kunkel Distinctive patterns of microRNA expression in primary muscular disorders PNAS 2007 104: 17016-17021; published online on October 17, 2007, 10.1073/pnas.0708115104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Immunology

Kazumichi Abe, Kim Phung Nguyen, Sean D. Fine, Ji-Hun Mo, Carol Shen, Steve Shenouda, Maripat Corr, Steffen Jung, Jongdae Lee, Lars Eckmann, and Eyal Raz

Conventional dendritic cells regulate the outcome of colonic inflammation independently of T cells
PNAS 2007 104: 17022-17027; published online on October 17, 2007, 10.1073/pnas.0708469104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

Junsoo Park, Kwangsoo Kim, Eun-Ju Lee, Yun-Jee Seo, Si-Nae Lim, Kyoungsook Park, Seung Bae Rho, Seung-Hoon Lee, and Je-Ho Lee

Elevated level of SUMOylated IRF-1 in tumor cells interferes with IRF-1-mediated apoptosis
PNAS 2007 104: 17028-17033; published online on October 17, 2007, 10.1073/pnas.0609852104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

Hayley G. Evans, Tesha Suddason, Ian Jackson, Leonie S. Taams, and Graham M. Lord

Optimal induction of T helper 17 cells in humans requires T cell receptor ligation in the context of Toll-like receptor-activated monocytes
PNAS 2007 104: 17034-17039; published online on October 17, 2007, 10.1073/pnas.0708426104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

Janet M. Wenzlau, Kirstine Juhl, Liping Yu, Ong Moua, Suparna A. Sarkar, Peter Gottlieb, Marian Rewers, George S. Eisenbarth, Jan Jensen, Howard W. Davidson, and John C. Hutton

The cation efflux transporter ZnT8 (Slc30A8) is a major autoantigen in human type 1 diabetes
PNAS 2007 104: 17040-17045; published online on October 17, 2007, 10.1073/pnas.0705894104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Xiaoping Cui and Katheryn Meek

Linking double-stranded DNA breaks to the recombination activating gene complex directs repair to the nonhomologous end-joining pathway
PNAS 2007 104: 17046-17051; published online on October 15, 2007, 10.1073/pnas.0610928104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Sean T. Kim, Patrick E. Fields, and Richard A. Flavell

Demethylation of a specific hypersensitive site in the Th2 locus control region
PNAS 2007 104: 17052-17057; published online on October 12, 2007, 10.1073/pnas.0708293104 [Abstract] [Full Text] [Figures Only] [PDF]  

Melanie A. Samuel, Hong Wang, Venkatraman Siddharthan, John D. Morrey, and Michael S. Diamond Axonal transport mediates West Nile virus entry into the central nervous system and induces acute flaccid paralysis PNAS 2007 104: 17140-17145; published online on October 15, 2007, 10.1073/pnas.0705837104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Medical Sciences

James D. Reynolds, Gregory S. Ahearn, Michael Angelo, Jian Zhang, Fred Cobb, and Jonathan S. Stamler

S-nitrosohemoglobin deficiency: A mechanism for loss of physiological activity in banked blood
PNAS 2007 104: 17058-17062; published online on October 11, 2007, 10.1073/pnas.0707958104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  
See Commentary on page 19165

Elliott Bennett-Guerrero, Tim H. Veldman, Allan Doctor, Marilyn J. Telen, Thomas L. Ortel, T. Scott Reid, Melissa A. Mulherin, Hongmei Zhu, Raymond D. Buck, Robert M. Califf, and Timothy J. McMahon Evolution of adverse changes in stored RBCs PNAS 2007 104: 17063-17068; published online on October 11, 2007, 10.1073/pnas.0708160104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE   See Commentary on page 19165

John M. L. Ebos, Christina R. Lee, James G. Christensen, Anthony J. Mutsaers, and Robert S. Kerbel Multiple circulating proangiogenic factors induced by sunitinib malate are tumor-independent and correlate with antitumor efficacy PNAS 2007 104: 17069-17074; published online on October 17, 2007, 10.1073/pnas.0708148104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Dongyan Zhang, Zhen-Xiang Liu, Cheol Soo Choi, Liqun Tian, Richard Kibbey, Jianying Dong, Gary W. Cline, Philip A. Wood, and Gerald I. Shulman Mitochondrial dysfunction due to long-chain Acyl-CoA dehydrogenase deficiency causes hepatic steatosis and hepatic insulin resistance PNAS 2007 104: 17075-17080; published online on October 16, 2007, 10.1073/pnas.0707060104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Anuradha Natarajan, Bettina Wagner, and Maria Sibilia

The EGF receptor is required for efficient liver regeneration
PNAS 2007 104: 17081-17086; published online on October 16, 2007, 10.1073/pnas.0704126104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

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