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THIS WEEK IN PNAS

In This Issue
PNAS 2007 104: 19657-19658. [Full Text] [PDF]  

COMMENTARIES

Vaughn M. Bryant, Jr.

Microscopic evidence for the domestication and spread of maize
PNAS 2007 104: 19659-19660; published online on December 4, 2007, 10.1073/pnas.0710327105 [Extract] [Full Text] [PDF]  
See companion article on page 17608 in issue 45 of volume 104

Raymond L. Bernor

New apes fill the gap
PNAS 2007 104: 19661-19662; published online on December 5, 2007, 10.1073/pnas.0710109105 [Extract] [Full Text] [PDF]  
See companion article on page 19220 in issue 49 of volume 104

Katya Rubia

Neuro-anatomic evidence for the maturational delay hypothesis of ADHD
PNAS 2007 104: 19663-19664; published online on December 6, 2007, 10.1073/pnas.0710329105 [Extract] [Full Text] [PDF]  
See companion article on page 19649 in issue 49 of volume 104

SPECIAL FEATURE

Perspectives

William E. Easterling

From the Cover: Climate Change and Food Security Special Feature: Climate change and the adequacy of food and timber in the 21st century
PNAS 2007 104: 19679; published online on December 6, 2007, 10.1073/pnas.0710388104 [Extract] [Full Text] [PDF]  

Research Articles

John F. Morton

Climate Change and Food Security Special Feature: The impact of climate change on smallholder and subsistence agriculture
PNAS 2007 104: 19680-19685; published online on December 6, 2007, 10.1073/pnas.0701855104 [Abstract] [Full Text] [PDF]  

Francesco N. Tubiello, Jean-François Soussana, and S. Mark Howden

Climate Change and Food Security Special Feature: Crop and pasture response to climate change
PNAS 2007 104: 19686-19690; published online on December 6, 2007, 10.1073/pnas.0701728104 [Abstract] [Full Text] [PDF]  

S. Mark Howden, Jean-François Soussana, Francesco N. Tubiello, Netra Chhetri, Michael Dunlop, and Holger Meinke

Climate Change and Food Security Special Feature: Adapting agriculture to climate change
PNAS 2007 104: 19691-19696; published online on December 6, 2007, 10.1073/pnas.0701890104 [Abstract] [Full Text] [PDF] [Supporting Figure]  

Andrei P. Kirilenko and Roger A. Sedjo

Climate Change and Food Security Special Feature: Climate change impacts on forestry
PNAS 2007 104: 19697-19702; published online on December 6, 2007, 10.1073/pnas.0701424104 [Abstract] [Full Text] [Figures Only] [PDF]  

Josef Schmidhuber and Francesco N. Tubiello

Climate Change and Food Security Special Feature: Global food security under climate change
PNAS 2007 104: 19703-19708; published online on December 6, 2007, 10.1073/pnas.0701976104 [Abstract] [Full Text] [Figures Only] [PDF]  

K. M. Brander

Climate Change and Food Security Special Feature: Global fish production and climate change
PNAS 2007 104: 19709-19714; published online on December 6, 2007, 10.1073/pnas.0702059104 [Abstract] [Full Text] [Figures Only] [PDF]  

PROFILES

Beth Azar

Profile of Steven Henikoff
PNAS 2007 104: 19665-19667; published online on December 6, 2007, 10.1073/pnas.0710322104 [Extract] [Full Text] [Figures Only] [PDF]  

Kaspar Mossman

Profile of Joachim Frank
PNAS 2007 104: 19668-19670; published online on December 4, 2007, 10.1073/pnas.0710323105 [Extract] [Full Text] [Figures Only] [PDF]  

PHYSICAL SCIENCES

Chemistry

R. Dean Astumian

Adiabatic operation of a molecular machine
PNAS 2007 104: 19715-19718; published online on December 5, 2007, 10.1073/pnas.0708040104 [Abstract] [Full Text] [Figures Only] [PDF]  

Engineering

Brad H. McRae and Paul Beier

Circuit theory predicts gene flow in plant and animal populations
PNAS 2007 104: 19885-19890; published online on December 3, 2007, 10.1073/pnas.0706568104 [Abstract] [Full Text] [Figures Only] [PDF]  

Environmental Sciences

Geology

Peter L. Nester, Eugenia Gayó, Claudio Latorre, Teresa E. Jordan, and Nicolás Blanco

Perennial stream discharge in the hyperarid Atacama Desert of northern Chile during the latest Pleistocene
PNAS 2007 104: 19724-19729; published online on December 3, 2007, 10.1073/pnas.0705373104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Table]  

Geophysics

A. Grinsted, J. C. Moore, and S. Jevrejeva

Observational evidence for volcanic impact on sea level and the global water cycle
PNAS 2007 104: 19730-19734; published online on December 3, 2007, 10.1073/pnas.0705825104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Mathematics

Fan Chung

The heat kernel as the pagerank of a graph
PNAS 2007 104: 19735-19740; published online on December 5, 2007, 10.1073/pnas.0708838104 [Abstract] [Full Text] [PDF]  

Statistics

F. Baldovin and A. L. Stella

Scaling and efficiency determine the irreversible evolution of a market
PNAS 2007 104: 19741-19744; published online on December 5, 2007, 10.1073/pnas.0706046104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Text]  

SOCIAL SCIENCES

Anthropology

Economic Sciences

F. Baldovin and A. L. Stella

Scaling and efficiency determine the irreversible evolution of a market
PNAS 2007 104: 19741-19744; published online on December 5, 2007, 10.1073/pnas.0706046104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Text]  

Psychology

Ran R. Hassin, Melissa J. Ferguson, Daniella Shidlovski, and Tamar Gross

Subliminal exposure to national flags affects political thought and behavior
PNAS 2007 104: 19757-19761; published online on December 4, 2007, 10.1073/pnas.0704679104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Social Sciences

John F. Morton

Climate Change and Food Security Special Feature: The impact of climate change on smallholder and subsistence agriculture
PNAS 2007 104: 19680-19685; published online on December 6, 2007, 10.1073/pnas.0701855104 [Abstract] [Full Text] [PDF]  

Judith M. Burkart, Ernst Fehr, Charles Efferson, and Carel P. van Schaik From the Cover: Other-regarding preferences in a non-human primate: Common marmosets provision food altruistically PNAS 2007 104: 19762-19766; published online on December 5, 2007, 10.1073/pnas.0710310104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]

BIOLOGICAL SCIENCES

Agricultural Sciences

John F. Morton

Climate Change and Food Security Special Feature: The impact of climate change on smallholder and subsistence agriculture
PNAS 2007 104: 19680-19685; published online on December 6, 2007, 10.1073/pnas.0701855104 [Abstract] [Full Text] [PDF]  

Francesco N. Tubiello, Jean-François Soussana, and S. Mark Howden

Climate Change and Food Security Special Feature: Crop and pasture response to climate change
PNAS 2007 104: 19686-19690; published online on December 6, 2007, 10.1073/pnas.0701728104 [Abstract] [Full Text] [PDF]  

S. Mark Howden, Jean-François Soussana, Francesco N. Tubiello, Netra Chhetri, Michael Dunlop, and Holger Meinke

Climate Change and Food Security Special Feature: Adapting agriculture to climate change
PNAS 2007 104: 19691-19696; published online on December 6, 2007, 10.1073/pnas.0701890104 [Abstract] [Full Text] [PDF] [Supporting Figure]  

Anthropology

Biochemistry

Xiao Yu, Jin-Peng Sun, Yantao He, Xiaoling Guo, Sijiu Liu, Bo Zhou, Andy Hudmon, and Zhong-Yin Zhang

Structure, inhibitor, and regulatory mechanism of Lyp, a lymphoid-specific tyrosine phosphatase implicated in autoimmune diseases
PNAS 2007 104: 19767-19772; published online on December 3, 2007, 10.1073/pnas.0706233104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Matthew E. Merritt, Crystal Harrison, Charles Storey, F. Mark Jeffrey, A. Dean Sherry, and Craig R. Malloy

Hyperpolarized ¹³C allows a direct measure of flux through a single enzyme-catalyzed step by NMR
PNAS 2007 104: 19773-19777; published online on December 3, 2007, 10.1073/pnas.0706235104 [Abstract] [Full Text] [Figures Only] [PDF]  

Alexander Heuck, Tung-Gia Du, Stephan Jellbauer, Klaus Richter, Claudia Kruse, Sigrun Jaklin, Marisa Müller, Johannes Buchner, Ralf-Peter Jansen, and Dierk Niessing

Monomeric myosin V uses two binding regions for the assembly of stable translocation complexes
PNAS 2007 104: 19778-19783; published online on December 4, 2007, 10.1073/pnas.0706780104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Yan Wu, Charles Eigenbrot, Wei-Ching Liang, Scott Stawicki, Steven Shia, Bin Fan, Rajkumar Ganesan, Michael T. Lipari, and Daniel Kirchhofer Structural insight into distinct mechanisms of protease inhibition by antibodies PNAS 2007 104: 19784-19789; published online on December 5, 2007, 10.1073/pnas.0708251104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Timothée Lionnet, Michelle M. Spiering, Stephen J. Benkovic, David Bensimon, and Vincent Croquette

Real-time observation of bacteriophage T4 gp41 helicase reveals an unwinding mechanism
PNAS 2007 104: 19790-19795; published online on December 5, 2007, 10.1073/pnas.0709793104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Ci-Di Chen, Sonia Podvin, Earl Gillespie, Susan E. Leeman, and Carmela R. Abraham

Insulin stimulates the cleavage and release of the extracellular domain of Klotho by ADAM10 and ADAM17
PNAS 2007 104: 19796-19801; published online on December 3, 2007, 10.1073/pnas.0709805104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Erin D. Lew, Jae Hyun Bae, Edyta Rohmann, Bernd Wollnik, and Joseph Schlessinger

Structural basis for reduced FGFR2 activity in LADD syndrome: Implications for FGFR autoinhibition and activation
PNAS 2007 104: 19802-19807; published online on December 3, 2007, 10.1073/pnas.0709905104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Biophysics

Benjamin J. Blaise, Jean Giacomotto, Bénédicte Elena, Marc-Emmanuel Dumas, Pierre Toulhoat, Laurent Ségalat, and Lyndon Emsley

Metabotyping of Caenorhabditis elegans reveals latent phenotypes
PNAS 2007 104: 19808-19812; published online on December 5, 2007, 10.1073/pnas.0707393104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Evgeniya Sadovsky and Ofer Yifrach

Principles underlying energetic coupling along an allosteric communication trajectory of a voltage-activated K⁺ channel
PNAS 2007 104: 19813-19818; published online on December 5, 2007, 10.1073/pnas.0708120104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Diego U. Ferreiro, Joseph A. Hegler, Elizabeth A. Komives, and Peter G. Wolynes

Localizing frustration in native proteins and protein assemblies
PNAS 2007 104: 19819-19824; published online on December 5, 2007, 10.1073/pnas.0709915104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Ludovico Sutto, Joachim Lätzer, Joseph A. Hegler, Diego U. Ferreiro, and Peter G. Wolynes

Consequences of localized frustration for the folding mechanism of the IM7 protein
PNAS 2007 104: 19825-19830; published online on December 5, 2007, 10.1073/pnas.0709922104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Chikashi Toyoshima, Yoshiyuki Norimatsu, Shiho Iwasawa, Takeo Tsuda, and Haruo Ogawa

How processing of aspartylphosphate is coupled to lumenal gating of the ion pathway in the calcium pump
PNAS 2007 104: 19831-19836; published online on December 5, 2007, 10.1073/pnas.0709978104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Cell Biology

Hema Vaidyanathan, John Opoku-Ansah, Sandra Pastorino, Hema Renganathan, Michelle L. Matter, and Joe W. Ramos

ERK MAP kinase is targeted to RSK2 by the phosphoprotein PEA-15
PNAS 2007 104: 19837-19842; published online on December 6, 2007, 10.1073/pnas.0704514104 [Abstract] [Full Text] [Figures Only] [PDF]  

Bhaskarjyoti Sarmah, Virginia P. Winfrey, Gary E. Olson, Bruce Appel, and Susan R. Wente

A role for the inositol kinase Ipk1 in ciliary beating and length maintenance
PNAS 2007 104: 19843-19848; published online on December 3, 2007, 10.1073/pnas.0706934104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

A. Rosa, M. Ballarino, A. Sorrentino, O. Sthandier, F. G. De Angelis, M. Marchioni, B. Masella, A. Guarini, A. Fatica, C. Peschle, and I. Bozzoni

The interplay between the master transcription factor PU.1 and miR-424 regulates human monocyte/macrophage differentiation
PNAS 2007 104: 19849-19854; published online on December 3, 2007, 10.1073/pnas.0706963104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

Matthew P. Stokes, John Rush, Joan MacNeill, Jian Min Ren, Kam Sprott, Julie Nardone, Vicky Yang, Sean A. Beausoleil, Steven P. Gygi, Mark Livingstone, Hui Zhang, Roberto D. Polakiewicz, and Michael J. Comb

Profiling of UV-induced ATM/ATR signaling pathways
PNAS 2007 104: 19855-19860; published online on December 6, 2007, 10.1073/pnas.0707579104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Sayyed K. Zaidi, Sandhya Pande, Jitesh Pratap, Tripti Gaur, Simina Grigoriu, Syed A. Ali, Janet L. Stein, Jane B. Lian, Andre J. van Wijnen, and Gary S. Stein

Runx2 deficiency and defective subnuclear targeting bypass senescence to promote immortalization and tumorigenic potential
PNAS 2007 104: 19861-19866; published online on December 5, 2007, 10.1073/pnas.0709650104 [Abstract] [Full Text] [Figures Only] [PDF]  

Craig M. Forester, Jessica Maddox, Justin V. Louis, Jozef Goris, and David M. Virshup

Control of mitotic exit by PP2A regulation of Cdc25C and Cdk1
PNAS 2007 104: 19867-19872; published online on December 4, 2007, 10.1073/pnas.0709879104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

Developmental Biology

Giordano W. Calloni, Corinne Glavieux-Pardanaud, Nicole M. Le Douarin, and Elisabeth Dupin

Sonic Hedgehog promotes the development of multipotent neural crest progenitors endowed with both mesenchymal and neural potentials
PNAS 2007 104: 19879-19884; published online on December 6, 2007, 10.1073/pnas.0708806104 [Abstract] [Full Text] [Figures Only] [PDF]  

Ecology

Peter L. Nester, Eugenia Gayó, Claudio Latorre, Teresa E. Jordan, and Nicolás Blanco

Perennial stream discharge in the hyperarid Atacama Desert of northern Chile during the latest Pleistocene
PNAS 2007 104: 19724-19729; published online on December 3, 2007, 10.1073/pnas.0705373104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Table]  

Brad H. McRae and Paul Beier

Circuit theory predicts gene flow in plant and animal populations
PNAS 2007 104: 19885-19890; published online on December 3, 2007, 10.1073/pnas.0706568104 [Abstract] [Full Text] [Figures Only] [PDF]  

Jens M. Olesen, Jordi Bascompte, Yoko L. Dupont, and Pedro Jordano

The modularity of pollination networks
PNAS 2007 104: 19891-19896; published online on December 4, 2007, 10.1073/pnas.0706375104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

David W. Steadman, Richard Franz, Gary S. Morgan, Nancy A. Albury, Brian Kakuk, Kenneth Broad, Shelley E. Franz, Keith Tinker, Michael P. Pateman, Terry A. Lott, David M. Jarzen, and David L. Dilcher

Exceptionally well preserved late Quaternary plant and vertebrate fossils from a blue hole on Abaco, The Bahamas
PNAS 2007 104: 19897-19902; published online on December 5, 2007, 10.1073/pnas.0709572104 [Abstract] [Full Text] [Figures Only] [PDF]  

Evolution

David R. Vieites, Mi-Sook Min, and David B. Wake

Rapid diversification and dispersal during periods of global warming by plethodontid salamanders
PNAS 2007 104: 19903-19907; published online on December 5, 2007, 10.1073/pnas.0705056104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Christopher E. Lane, Krystal van den Heuvel, Catherine Kozera, Bruce A. Curtis, Byron J. Parsons, Sharen Bowman, and John M. Archibald

Nucleomorph genome of Hemiselmis andersenii reveals complete intron loss and compaction as a driver of protein structure and function
PNAS 2007 104: 19908-19913; published online on December 6, 2007, 10.1073/pnas.0707419104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Andrew R. Wargo, Silvie Huijben, Jacobus C. de Roode, James Shepherd, and Andrew F. Read Competitive release and facilitation of drug-resistant parasites after therapeutic chemotherapy in a rodent malaria model PNAS 2007 104: 19914-19919; published online on December 3, 2007, 10.1073/pnas.0707766104 [Abstract] [Full Text] [Figures Only] [PDF] OPEN ACCESS ARTICLE

Erik B. Dopman and Daniel L. Hartl

A portrait of copy-number polymorphism in Drosophila melanogaster
PNAS 2007 104: 19920-19925; published online on December 4, 2007, 10.1073/pnas.0709888104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Oskar Hallatschek, Pascal Hersen, Sharad Ramanathan, and David R. Nelson Genetic drift at expanding frontiers promotes gene segregation PNAS 2007 104: 19926-19930; published online on December 4, 2007, 10.1073/pnas.0710150104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Genetics

Ultan McDermott, Sreenath V. Sharma, Lori Dowell, Patricia Greninger, Clara Montagut, Jennifer Lamb, Heidi Archibald, Raul Raudales, Angela Tam, Diana Lee, S. Michael Rothenberg, Jeffrey G. Supko, Raffaella Sordella, Lindsey E. Ulkus, A. John Iafrate, Shyamala Maheswaran, Ching Ni Njauw, Hensin Tsao, Lisa Drew, Jeff H. Hanke, Xiao-Jun Ma, Mark G. Erlander, Nathanael S. Gray, Daniel A. Haber, and Jeffrey Settleman

Identification of genotype-correlated sensitivity to selective kinase inhibitors by using high-throughput tumor cell line profiling
PNAS 2007 104: 19936-19941; published online on December 6, 2007, 10.1073/pnas.0707498104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Todd Lencz, Christophe Lambert, Pamela DeRosse, Katherine E. Burdick, T. Vance Morgan, John M. Kane, Raju Kucherlapati, and Anil K. Malhotra Runs of homozygosity reveal highly penetrant recessive loci in schizophrenia PNAS 2007 104: 19942-19947; published online on December 5, 2007, 10.1073/pnas.0710021104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Daniel F. Tardiff, Katharine C. Abruzzi, and Michael Rosbash

Protein characterization of Saccharomyces cerevisiae RNA polymerase II after in vivo cross-linking
PNAS 2007 104: 19948-19953; published online on December 5, 2007, 10.1073/pnas.0710179104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Immunology

Jaeseok Yang, Matthew O. Brook, Manuela Carvalho-Gaspar, Jidong Zhang, Hilda E. Ramon, Mohamed H. Sayegh, Kathryn J. Wood, Laurence A. Turka, and Nick D. Jones

Allograft rejection mediated by memory T cells is resistant to regulation
PNAS 2007 104: 19954-19959; published online on November 27, 2007, 10.1073/pnas.0704397104 [Abstract] [Full Text] [Figures Only] [PDF]  

Luka Cicin-Sain, Ilhem Messaoudi, Byung Park, Noreen Currier, Shannon Planer, Miranda Fischer, Shane Tackitt, Dragana Nikolich-Zugich, Alfred Legasse, Michael K. Axthelm, Louis J. Picker, Motomi Mori, and Janko Nikolich-Zugich

Dramatic increase in naïve T cell turnover is linked to loss of naïve T cells from old primates
PNAS 2007 104: 19960-19965; published online on December 4, 2007, 10.1073/pnas.0705905104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

Anouk L. Feitsma, Jane Worthington, Annette H. M. van der Helm-van Mil, Darren Plant, Wendy Thomson, Jennie Ursum, Dirkjan van Schaardenburg, Irene E. van der Horst-Bruinsma, Jon J. van Rood, Tom W. J. Huizinga, René E. M. Toes, and René R. P. de Vries Protective effect of noninherited maternal HLA-DR antigens on rheumatoid arthritis development PNAS 2007 104: 19966-19970; published online on December 6, 2007, 10.1073/pnas.0710260104 [Abstract] [Full Text] [PDF] OPEN ACCESS ARTICLE

Medical Sciences

Shuangli Mi, Jun Lu, Miao Sun, Zejuan Li, Hao Zhang, Mary Beth Neilly, Yungui Wang, Zhijian Qian, Jie Jin, Yanming Zhang, Stefan K. Bohlander, Michelle M. Le Beau, Richard A. Larson, Todd R. Golub, Janet D. Rowley, and Jianjun Chen

MicroRNA expression signatures accurately discriminate acute lymphoblastic leukemia from acute myeloid leukemia
PNAS 2007 104: 19971-19976; published online on December 4, 2007, 10.1073/pnas.0709313104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Elias Gounaris, Susan E. Erdman, Clifford Restaino, Michael F. Gurish, Daniel S. Friend, Fotini Gounari, David M. Lee, Guoying Zhang, Jonathan N. Glickman, Kichul Shin, Varada P. Rao, Theofilos Poutahidis, Ralph Weissleder, Kelly M. McNagny, and Khashayarsha Khazaie Mast cells are an essential hematopoietic component for polyp development PNAS 2007 104: 19977-19982; published online on December 6, 2007, 10.1073/pnas.0704620104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures] OPEN ACCESS ARTICLE

Xu-Bao Shi, Lingru Xue, Joy Yang, Ai-Hong Ma, Jianjun Zhao, Ma Xu, Clifford G. Tepper, Christopher P. Evans, Hsing-Jien Kung, and Ralph W. deVere White

An androgen-regulated miRNA suppresses Bak1 expression and induces androgen-independent growth of prostate cancer cells
PNAS 2007 104: 19983-19988; published online on December 3, 2007, 10.1073/pnas.0706641104 [Abstract] [Full Text] [Figures Only] [PDF] [Suppporting Information]  

Rupak Datta, Abdul Waheed, Gul N. Shah, and William S. Sly

Signal sequence mutation in autosomal dominant form of hypoparathyroidism induces apoptosis that is corrected by a chemical chaperone
PNAS 2007 104: 19989-19994; published online on December 3, 2007, 10.1073/pnas.0708725104 [Abstract] [Full Text] [Figures Only] [PDF]  

Jacob Selhub, Martha Savaria Morris, and Paul F. Jacques In vitamin B12 deficiency, higher serum folate is associated with increased total homocysteine and methylmalonic acid concentrations PNAS 2007 104: 19995-20000; published online on December 4, 2007, 10.1073/pnas.0709487104 [Abstract] [Full Text] [Figures Only] [PDF] OPEN ACCESS ARTICLE

Hui Li, XianYong Ma, Jinglan Wang, Jason Koontz, Marisa Nucci, and Jeffrey Sklar

Effects of rearrangement and allelic exclusion of JJAZ1/SUZ12 on cell proliferation and survival
PNAS 2007 104: 20001-20006; published online on December 6, 2007, 10.1073/pnas.0709986104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Text]  

Rameen Beroukhim, Gad Getz, Leia Nghiemphu, Jordi Barretina, Teli Hsueh, David Linhart, Igor Vivanco, Jeffrey C. Lee, Julie H. Huang, Sethu Alexander, Jinyan Du, Tweeny Kau, Roman K. Thomas, Kinjal Shah, Horacio Soto, Sven Perner, John Prensner, Ralph M. Debiasi, Francesca Demichelis, Charlie Hatton, Mark A. Rubin, Levi A. Garraway, Stan F. Nelson, Linda Liau, Paul S. Mischel, Tim F. Cloughesy, Matthew Meyerson, Todd A. Golub, Eric S. Lander, Ingo K. Mellinghoff, and William R. Sellers

Assessing the significance of chromosomal aberrations in cancer: Methodology and application to glioma
PNAS 2007 104: 20007-20012; published online on December 6, 2007, 10.1073/pnas.0710052104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Donald Metcalf, Stefan Glaser, Sandra Mifsud, Ladina Di Rago, and Lorraine Robb

The preleukemic state of mice reconstituted with Mixl1-transduced marrow cells
PNAS 2007 104: 20013-20018; published online on December 3, 2007, 10.1073/pnas.0710339104 [Abstract] [Full Text] [Figures Only] [PDF]  

Microbiology

Keith Jarosinski, Lisa Kattenhorn, Benedikt Kaufer, Hidde Ploegh, and Nikolaus Osterrieder A herpesvirus ubiquitin-specific protease is critical for efficient T cell lymphoma formation PNAS 2007 104: 20025-20030; published online on December 4, 2007, 10.1073/pnas.0706295104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Maria Zhadina, Myra O. McClure, Marc C. Johnson, and Paul D. Bieniasz

Ubiquitin-dependent virus particle budding without viral protein ubiquitination
PNAS 2007 104: 20031-20036; published online on December 3, 2007, 10.1073/pnas.0708002104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Dai Wang, Qian-Chun Yu, Jörg Schröer, Eain Murphy, and Thomas Shenk

Human cytomegalovirus uses two distinct pathways to enter retinal pigmented epithelial cells
PNAS 2007 104: 20037-20042; published online on December 5, 2007, 10.1073/pnas.0709704104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Tables]  

Subhash Singh, Matthew Plassmeyer, Deepak Gaur, and Louis H. Miller Mononeme: A new secretory organelle in Plasmodium falciparum merozoites identified by localization of rhomboid-1 protease PNAS 2007 104: 20043-20048; published online on November 28, 2007, 10.1073/pnas.0709999104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Neuroscience

Sebastian Kowsky, Charlotte Pöppelmeyer, Edgar R. Kramer, Björn H. Falkenburger, Anja Kruse, Rüdiger Klein, and Jörg B. Schulz

RET signaling does not modulate MPTP toxicity but is required for regeneration of dopaminergic axon terminals
PNAS 2007 104: 20049-20054; published online on December 4, 2007, 10.1073/pnas.0706177104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Jae-Won Yang, Helene Vacher, Kang-Sik Park, Eliana Clark, and James S. Trimmer

Trafficking-dependent phosphorylation of Kv1.2 regulates voltage-gated potassium channel cell surface expression
PNAS 2007 104: 20055-20060; published online on December 3, 2007, 10.1073/pnas.0708574104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Todd A. Kuiken, Paul D. Marasco, Blair A. Lock, R. Norman Harden, and Julius P. A. Dewald From the Cover: Redirection of cutaneous sensation from the hand to the chest skin of human amputees with targeted reinnervation PNAS 2007 104: 20061-20066; published online on November 28, 2007, 10.1073/pnas.0706525104 [Abstract] [Full Text] [Figures Only] [PDF] OPEN ACCESS ARTICLE