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THIS WEEK IN PNAS

In This Issue
PNAS 2007 104: 2555-2556. [Full Text] [PDF]  

COMMENTARIES

Giulia Galli

Dissecting hydrophobicity
PNAS 2007 104: 2557-2558; published online before print February 13 2007, 10.1073/pnas.0700176104 [Extract] [Full Text] [Figures Only] [PDF]  
See companion article on page 2626

John S. Parkinson

Ancient chemoreceptors retain their flexibility
PNAS 2007 104: 2559-2560; published online before print February 14 2007, 10.1073/pnas.0700278104 [Extract] [Full Text] [Figures Only] [PDF]  
See companion article on page 2885

Marcelino T. Suzuki and Oded Béjà

An elusive marine photosynthetic bacterium is finally unveiled
PNAS 2007 104: 2561-2562; published online before print February 13 2007, 10.1073/pnas.0700175104 [Extract] [Full Text] [Figures Only] [PDF]  
See companion article on page 2891

PHYSICAL SCIENCES

Chemistry

Phillip W. Snyder, Gwangrog Lee, Piotr E. Marszalek, Robert L. Clark, and Eric J. Toone

A stochastic, cantilever approach to the evaluation of solution phase thermodynamic quantities
PNAS 2007 104: 2579-2584; published online before print February 16 2007, 10.1073/pnas.0606604104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Je-Luen Li, Roberto Car, Chao Tang, and Ned S. Wingreen From the Cover: Hydrophobic interaction and hydrogen-bond network for a methane pair in liquid water PNAS 2007 104: 2626-2630; published online before print February 13 2007, 10.1073/pnas.0610945104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]   See Commentary on page 2557

Peter J. Bond and Mark S. P. Sansom Bilayer deformation by the Kv channel voltage sensor domain revealed by self-assembly simulations PNAS 2007 104: 2631-2636; published online before print February 14 2007, 10.1073/pnas.0606822104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Ilya J. Finkelstein, Haruto Ishikawa, Seongheun Kim, Aaron M. Massari, and M. D. Fayer

Substrate binding and protein conformational dynamics measured by 2D-IR vibrational echo spectroscopy
PNAS 2007 104: 2637-2642; published online before print February 12 2007, 10.1073/pnas.0610027104 [Abstract] [Full Text] [Figures Only] [PDF]  

Engineering

Yun-Ling Wong, Samantha Sampson, Willem Andreas Germishuizen, Sunali Goonesekera, Giovanni Caponetti, Jerry Sadoff, Barry R. Bloom, and David Edwards

Drying a tuberculosis vaccine without freezing
PNAS 2007 104: 2591-2595; published online before print February 13 2007, 10.1073/pnas.0611430104 [Abstract] [Full Text] [Figures Only] [PDF]  

Physics

BIOLOGICAL SCIENCES

Applied Biological Sciences

Yun-Ling Wong, Samantha Sampson, Willem Andreas Germishuizen, Sunali Goonesekera, Giovanni Caponetti, Jerry Sadoff, Barry R. Bloom, and David Edwards

Drying a tuberculosis vaccine without freezing
PNAS 2007 104: 2591-2595; published online before print February 13 2007, 10.1073/pnas.0611430104 [Abstract] [Full Text] [Figures Only] [PDF]  

Masanori Takehashi, Mito Kanatsu-Shinohara, Kimiko Inoue, Narumi Ogonuki, Hiromi Miki, Shinya Toyokuni, Atsuo Ogura, and Takashi Shinohara

Adenovirus-mediated gene delivery into mouse spermatogonial stem cells
PNAS 2007 104: 2596-2601; published online before print February 13 2007, 10.1073/pnas.0609282104 [Abstract] [Full Text] [Figures Only] [PDF]  

Lisa M. Eubanks, Mark S. Hixon, Wei Jin, Sukwon Hong, Colin M. Clancy, William H. Tepp, Michael R. Baldwin, Carl J. Malizio, Michael C. Goodnough, Joseph T. Barbieri, Eric A. Johnson, Dale L. Boger, Tobin J. Dickerson, and Kim D. Janda

An in vitro and in vivo disconnect uncovered through high-throughput identification of botulinum neurotoxin A antagonists
PNAS 2007 104: 2602-2607; published online before print February 9 2007, 10.1073/pnas.0611213104 [Abstract] [Full Text] [Figures Only] [PDF]  

Biochemistry

Tsui-Ling Hsu, Sarah R. Hanson, Kuniyuki Kishikawa, Sheng-Kai Wang, Masaaki Sawa, and Chi-Huey Wong

Alkynyl sugar analogs for the labeling and visualization of glycoconjugates in cells
PNAS 2007 104: 2614-2619; published online before print February 12 2007, 10.1073/pnas.0611307104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Satwik Kamtekar, Michael J. Hohn, Hee-Sung Park, Michael Schnitzbauer, Anselm Sauerwald, Dieter Söll, and Thomas A. Steitz

Toward understanding phosphoseryl-tRNA^Cys formation: The crystal structure of Methanococcus maripaludis phosphoseryl-tRNA synthetase
PNAS 2007 104: 2620-2625; published online before print February 14 2007, 10.1073/pnas.0611504104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figure]  

Biophysics

Phillip W. Snyder, Gwangrog Lee, Piotr E. Marszalek, Robert L. Clark, and Eric J. Toone

A stochastic, cantilever approach to the evaluation of solution phase thermodynamic quantities
PNAS 2007 104: 2579-2584; published online before print February 16 2007, 10.1073/pnas.0606604104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Je-Luen Li, Roberto Car, Chao Tang, and Ned S. Wingreen From the Cover: Hydrophobic interaction and hydrogen-bond network for a methane pair in liquid water PNAS 2007 104: 2626-2630; published online before print February 13 2007, 10.1073/pnas.0610945104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]   See Commentary on page 2557

Peter J. Bond and Mark S. P. Sansom Bilayer deformation by the Kv channel voltage sensor domain revealed by self-assembly simulations PNAS 2007 104: 2631-2636; published online before print February 14 2007, 10.1073/pnas.0606822104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Ilya J. Finkelstein, Haruto Ishikawa, Seongheun Kim, Aaron M. Massari, and M. D. Fayer

Substrate binding and protein conformational dynamics measured by 2D-IR vibrational echo spectroscopy
PNAS 2007 104: 2637-2642; published online before print February 12 2007, 10.1073/pnas.0610027104 [Abstract] [Full Text] [Figures Only] [PDF]  

Wilfried Weber, Jörg Stelling, Markus Rimann, Bettina Keller, Marie Daoud-El Baba, Cornelia C. Weber, Dominique Aubel, and Martin Fussenegger A synthetic time-delay circuit in mammalian cells and mice PNAS 2007 104: 2643-2648; published online before print February 12 2007, 10.1073/pnas.0606398104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Samrat Mukhopadhyay, Rajaraman Krishnan, Edward A. Lemke, Susan Lindquist, and Ashok A. Deniz

A natively unfolded yeast prion monomer adopts an ensemble of collapsed and rapidly fluctuating structures
PNAS 2007 104: 2649-2654; published online before print February 13 2007, 10.1073/pnas.0611503104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Daniel Nettels, Irina V. Gopich, Armin Hoffmann, and Benjamin Schuler

Ultrafast dynamics of protein collapse from single-molecule photon statistics
PNAS 2007 104: 2655-2660; published online before print February 14 2007, 10.1073/pnas.0611093104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Kathryn A. Scott, Darwin O. V. Alonso, Satoshi Sato, Alan R. Fersht, and Valerie Daggett

Conformational entropy of alanine versus glycine in protein denatured states
PNAS 2007 104: 2661-2666; published online before print February 16 2007, 10.1073/pnas.0611182104 [Abstract] [Full Text] [Figures Only] [PDF]  

Björn M. Reinhard, Sassan Sheikholeslami, Alexander Mastroianni, A. Paul Alivisatos, and Jan Liphardt

Use of plasmon coupling to reveal the dynamics of DNA bending and cleavage by single EcoRV restriction enzymes
PNAS 2007 104: 2667-2672; published online before print February 16 2007, 10.1073/pnas.0607826104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Kyubong Jo, Dalia M. Dhingra, Theo Odijk, Juan J. de Pablo, Michael D. Graham, Rod Runnheim, Dan Forrest, and David C. Schwartz

A single-molecule barcoding system using nanoslits for DNA analysis
PNAS 2007 104: 2673-2678; published online before print February 12 2007, 10.1073/pnas.0611151104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Alan R. Lowe and Laura S. Itzhaki

Rational redesign of the folding pathway of a modular protein
PNAS 2007 104: 2679-2684; published online before print February 13 2007, 10.1073/pnas.0604653104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Tables]  

Ilya Belevich, Dmitry A. Bloch, Nikolai Belevich, Mårten Wikström, and Michael I. Verkhovsky Exploring the proton pump mechanism of cytochrome c oxidase in real time PNAS 2007 104: 2685-2690; published online before print February 9 2007, 10.1073/pnas.0608794104 [Abstract] [Full Text] [Figures Only] [PDF] OPEN ACCESS ARTICLE

Cell Biology

Varvara Trachana, Karel H. M. van Wely, Astrid Alonso Guerrero, Agnes Fütterer, and Carlos Martínez-A

Dido disruption leads to centrosome amplification and mitotic checkpoint defects compromising chromosome stability
PNAS 2007 104: 2691-2696; published online before print February 13 2007, 10.1073/pnas.0611132104 [Abstract] [Full Text] [Figures Only] [PDF]  

Irina Dulubova, Mikhail Khvotchev, Siqi Liu, Iryna Huryeva, Thomas C. Südhof, and Josep Rizo

Munc18-1 binds directly to the neuronal SNARE complex
PNAS 2007 104: 2697-2702; published online before print February 14 2007, 10.1073/pnas.0611318104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

Nadine Wiper-Bergeron, Houssein Abdou Salem, Julianna J. Tomlinson, Dongmei Wu, and Robert J. G. Haché

Glucocorticoid-stimulated preadipocyte differentiation is mediated through acetylation of C/EBP by GCN5
PNAS 2007 104: 2703-2708; published online before print February 14 2007, 10.1073/pnas.0607378104 [Abstract] [Full Text] [Figures Only] [PDF]  

Xinsheng Nan, Jianghui Hou, Alan Maclean, Jamal Nasir, Maria Jose Lafuente, Xinhua Shu, Skirmantas Kriaucionis, and Adrian Bird Interaction between chromatin proteins MECP2 and ATRX is disrupted by mutations that cause inherited mental retardation PNAS 2007 104: 2709-2714; published online before print February 12 2007, 10.1073/pnas.0608056104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Developmental Biology

Michael A. Ensslin and Barry D. Shur

The EGF repeat and discoidin domain protein, SED1/MFG-E8, is required for mammary gland branching morphogenesis
PNAS 2007 104: 2715-2720; published online before print February 13 2007, 10.1073/pnas.0610296104 [Abstract] [Full Text] [Figures Only] [PDF]  

Ajay Srivastava, Jose Carlos Pastor-Pareja, Tatsushi Igaki, Raymond Pagliarini, and Tian Xu

Basement membrane remodeling is essential for Drosophila disc eversion and tumor invasion
PNAS 2007 104: 2721-2726; published online before print February 14 2007, 10.1073/pnas.0611666104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Patrick R. H. Steinmetz, Fabiola Zelada-Gonzáles, Carola Burgtorf, Joachim Wittbrodt, and Detlev Arendt

Polychaete trunk neuroectoderm converges and extends by mediolateral cell intercalation
PNAS 2007 104: 2727-2732; published online before print February 14 2007, 10.1073/pnas.0606589104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Yong Cang, Jianxuan Zhang, Sally A. Nicholas, Arianna L. Kim, Pengbo Zhou, and Stephen P. Goff DDB1 is essential for genomic stability in developing epidermis PNAS 2007 104: 2733-2737; published online before print February 14 2007, 10.1073/pnas.0611311104 [Abstract] [Full Text] [Figures Only] [PDF] OPEN ACCESS ARTICLE

Jinsong Li, Valentina Greco, Géraldine Guasch, Elaine Fuchs, and Peter Mombaerts

Mice cloned from skin cells
PNAS 2007 104: 2738-2743; published online before print February 13 2007, 10.1073/pnas.0611358104 [Abstract] [Full Text] [Figures Only] [PDF]  

Tadahiro Iimura, Xuesong Yang, Cornelis J. Weijer, and Olivier Pourquié

Dual mode of paraxial mesoderm formation during chick gastrulation
PNAS 2007 104: 2744-2749; published online before print February 13 2007, 10.1073/pnas.0610997104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Robert W. Georgantas, III, Richard Hildreth, Sebastien Morisot, Jonathan Alder, Chang-gong Liu, Shelly Heimfeld, George A. Calin, Carlo M. Croce, and Curt I. Civin CD34+ hematopoietic stem-progenitor cell microRNA expression and function: A circuit diagram of differentiation control PNAS 2007 104: 2750-2755; published online before print February 9 2007, 10.1073/pnas.0610983104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Ecology

Robert C. Godfree, Peter H. Thrall, and Andrew G. Young

Enemy release after introduction of disease-resistant genotypes into plant–pathogen systems
PNAS 2007 104: 2756-2760; published online before print February 13 2007, 10.1073/pnas.0608356104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Alban Ramette and James M. Tiedje

Multiscale responses of microbial life to spatial distance and environmental heterogeneity in a patchy ecosystem
PNAS 2007 104: 2761-2766; published online before print February 12 2007, 10.1073/pnas.0610671104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Evolution

Andrew M. Shedlock, Christopher W. Botka, Shaying Zhao, Jyoti Shetty, Tingting Zhang, Jun S. Liu, Patrick J. Deschavanne, and Scott V. Edwards

Phylogenomics of nonavian reptiles and the structure of the ancestral amniote genome
PNAS 2007 104: 2767-2772; published online before print February 16 2007, 10.1073/pnas.0606204104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

James K. Cronin, Peter C. Bundock, Robert J. Henry, and Eviatar Nevo

Adaptive climatic molecular evolution in wild barley at the Isa defense locus
PNAS 2007 104: 2773-2778; published online before print February 14 2007, 10.1073/pnas.0611226104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Tables]  

Xun Gu and Zhixi Su

Tissue-driven hypothesis of genomic evolution and sequence-expression correlations
PNAS 2007 104: 2779-2784; published online before print February 14 2007, 10.1073/pnas.0610797104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Text]  

Jody Hey and Rasmus Nielsen

Integration within the Felsenstein equation for improved Markov chain Monte Carlo methods in population genetics
PNAS 2007 104: 2785-2790; published online before print February 14 2007, 10.1073/pnas.0611164104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Text]  

Genetics

Buxin Chen, Gary P. Newnam, and Yury O. Chernoff

Prion species barrier between the closely related yeast proteins is detected despite coaggregation
PNAS 2007 104: 2791-2796; published online before print February 12 2007, 10.1073/pnas.0611158104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Takehiko Usui and John H. J. Petrini The Saccharomyces cerevisiae 14-3-3 proteins Bmh1 and Bmh2 directly influence the DNA damage-dependent functions of Rad53 PNAS 2007 104: 2797-2802; published online before print February 13 2007, 10.1073/pnas.0611259104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Vasily Vasko, Allan V. Espinosa, William Scouten, Huiling He, Herbert Auer, Sandya Liyanarachchi, Alexander Larin, Victoria Savchenko, Gary L. Francis, Albert de la Chapelle, Motoyasu Saji, and Matthew D. Ringel

Gene expression and functional evidence of epithelial-to-mesenchymal transition in papillary thyroid carcinoma invasion
PNAS 2007 104: 2803-2808; published online before print February 12 2007, 10.1073/pnas.0610733104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Yihai Yu, Wubei Dong, Cara Altimus, Xiaojia Tang, James Griffith, Melissa Morello, Lisa Dudek, Jonathan Arnold, and Heinz-Bernd Schüttler A genetic network for the clock of Neurospora crassa PNAS 2007 104: 2809-2814; published online before print February 14 2007, 10.1073/pnas.0611005104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Kazuo Yamada, David J. Gerber, Yoshimi Iwayama, Tetsuo Ohnishi, Hisako Ohba, Tomoko Toyota, Jun Aruga, Yoshio Minabe, Susumu Tonegawa, and Takeo Yoshikawa From the Cover: Genetic analysis of the calcineurin pathway identifies members of the EGR gene family, specifically EGR3, as potential susceptibility candidates in schizophrenia PNAS 2007 104: 2815-2820; published online before print February 20 2007, 10.1073/pnas.0610765104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]

Immunology

Xunrong Luo, Kristin V. Tarbell, Hua Yang, Kathryn Pothoven, Samantha L. Bailey, Ruchuang Ding, Ralph M. Steinman, and Manikkam Suthanthiran

Dendritic cells with TGF-1 differentiate naïve CD4⁺CD25^– T cells into islet-protective Foxp3⁺ regulatory T cells
PNAS 2007 104: 2821-2826; published online before print February 16 2007, 10.1073/pnas.0611646104 [Abstract] [Full Text] [Figures Only] [PDF]  

Antonios O. Aliprantis, Jingsong Wang, John W. Fathman, Raphael Lemaire, David M. Dorfman, Robert Lafyatis, and Laurie H. Glimcher

Transcription factor T-bet regulates skin sclerosis through its function in innate immunity and via IL-13
PNAS 2007 104: 2827-2830; published online before print February 16 2007, 10.1073/pnas.0700021104 [Abstract] [Full Text] [Figures Only] [PDF]  

Melinda Ráki, Lars-Egil Fallang, Margit Brottveit, Elin Bergseng, Hanne Quarsten, Knut E. A. Lundin, and Ludvig M. Sollid Tetramer visualization of gut-homing gluten-specific T cells in the peripheral blood of celiac disease patients PNAS 2007 104: 2831-2836; published online before print February 16 2007, 10.1073/pnas.0608610104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Farhad Haghighi Rad, Hélène Le Buanec, Sébastien Paturance, Patrick Larcier, Philippe Genne, Bernhard Ryffel, Armand Bensussan, Bernard Bizzini, Robert C. Gallo, Daniel Zagury, and Georges Uzan VEGF kinoid vaccine, a therapeutic approach against tumor angiogenesis and metastases PNAS 2007 104: 2837-2842; published online before print February 14 2007, 10.1073/pnas.0611022104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Kerstin Kiefer, Jennifer Oshinsky, Jiyoon Kim, Pamela B. Nakajima, Gayle C. Bosma, and Melvin J. Bosma

The catalytic subunit of DNA–protein kinase (DNA-PKcs) is not required for Ig class-switch recombination
PNAS 2007 104: 2843-2848; published online before print February 12 2007, 10.1073/pnas.0611359104 [Abstract] [Full Text] [Figures Only] [PDF]  

Katrin Ramsauer, Matthias Farlik, Gordin Zupkovitz, Christian Seiser, Andrea Kröger, Hansjörg Hauser, and Thomas Decker

Distinct modes of action applied by transcription factors STAT1 and IRF1 to initiate transcription of the IFN--inducible gbp2 gene
PNAS 2007 104: 2849-2854; published online before print February 9 2007, 10.1073/pnas.0610944104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figure]  

Medical Sciences

Monica B. Pagano, Michel A. Bartoli, Terri L. Ennis, Dongli Mao, Pamela M. Simmons, Robert W. Thompson, and Christine T. N. Pham Critical role of dipeptidyl peptidase I in neutrophil recruitment during the development of experimental abdominal aortic aneurysms PNAS 2007 104: 2855-2860; published online before print February 14 2007, 10.1073/pnas.0606091104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures] OPEN ACCESS ARTICLE

Desiree M. Schumann, Kathrin Maedler, Isobel Franklin, Daniel Konrad, Joachim Størling, Marianne Böni-Schnetzler, Asllan Gjinovci, Michael O. Kurrer, Benoit R. Gauthier, Domenico Bosco, Axel Andres, Thierry Berney, Melanie Greter, Burkhard Becher, Alexander V. Chervonsky, Philippe A. Halban, Thomas Mandrup-Poulsen, Claes B. Wollheim, and Marc Y. Donath

The Fas pathway is involved in pancreatic cell secretory function
PNAS 2007 104: 2861-2866; published online before print February 13 2007, 10.1073/pnas.0611487104 [Abstract] [Full Text] [Figures Only] [PDF]  

Jong-Sup Bae, Likui Yang, and Alireza R. Rezaie

Receptors of the protein C activation and activated protein C signaling pathways are colocalized in lipid rafts of endothelial cells
PNAS 2007 104: 2867-2872; published online before print February 13 2007, 10.1073/pnas.0611493104 [Abstract] [Full Text] [Figures Only] [PDF]  

David F. Moore, Oleg V. Krokhin, Ronald C. Beavis, Markus Ries, Chevalia Robinson, Ehud Goldin, Roscoe O. Brady, John A. Wilkins, and Raphael Schiffmann Proteomics of specific treatment-related alterations in Fabry disease: A strategy to identify biological abnormalities PNAS 2007 104: 2873-2878; published online before print February 14 2007, 10.1073/pnas.0611315104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures] OPEN ACCESS ARTICLE

Laura K. McMullan, Arash Grakoui, Matthew J. Evans, Kathleen Mihalik, Montserrat Puig, Andrea D. Branch, Stephen M. Feinstone, and Charles M. Rice

Evidence for a functional RNA element in the hepatitis C virus core gene
PNAS 2007 104: 2879-2884; published online before print February 13 2007, 10.1073/pnas.0611267104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Microbiology

Bernhard M. Fuchs, Stefan Spring, Hanno Teeling, Christian Quast, Jörg Wulf, Martha Schattenhofer, Shi Yan, Steve Ferriera, Justin Johnson, Frank Oliver Glöckner, and Rudolf Amann From the Cover: Characterization of a marine gammaproteobacterium capable of aerobic anoxygenic photosynthesis PNAS 2007 104: 2891-2896; published online before print February 13 2007, 10.1073/pnas.0608046104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]   See Commentary on page 2561

Asparouh I. Iliev, Jasmin Roya Djannatian, Roland Nau, Timothy J. Mitchell, and Fred S. Wouters

Cholesterol-dependent actin remodeling via RhoA and Rac1 activation by the Streptococcus pneumoniae toxin pneumolysin
PNAS 2007 104: 2897-2902; published online before print February 14 2007, 10.1073/pnas.0608213104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Ravi P. Subramanian and Robert J. Geraghty

Herpes simplex virus type 1 mediates fusion through a hemifusion intermediate by sequential activity of glycoproteins D, H, L, and B
PNAS 2007 104: 2903-2908; published online before print February 13 2007, 10.1073/pnas.0608374104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

Peter Hebbeln, Dmitry A. Rodionov, Anja Alfandega, and Thomas Eitinger

Biotin uptake in prokaryotes by solute transporters with an optional ATP-binding cassette-containing module
PNAS 2007 104: 2909-2914; published online before print February 14 2007, 10.1073/pnas.0609905104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

David Derse, Shawn A. Hill, Gerald Princler, Patricia Lloyd, and Gisela Heidecker

Resistance of human T cell leukemia virus type 1 to APOBEC3G restriction is mediated by elements in nucleocapsid
PNAS 2007 104: 2915-2920; published online before print February 13 2007, 10.1073/pnas.0609444104 [Abstract] [Full Text] [Figures Only] [PDF]  

Michael J. Gray and Jorge C. Escalante-Semerena

Single-enzyme conversion of FMNH₂ to 5,6-dimethylbenzimidazole, the lower ligand of B₁₂
PNAS 2007 104: 2921-2926; published online before print February 14 2007, 10.1073/pnas.0609270104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Zhan Gao, Chi-hong Tseng, Zhiheng Pei, and Martin J. Blaser

Molecular analysis of human forearm superficial skin bacterial biota
PNAS 2007 104: 2927-2932; published online before print February 9 2007, 10.1073/pnas.0607077104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Sonya P. Lad, Jiali Li, Jean da Silva Correia, Qilin Pan, Shilpa Gadwal, Richard J. Ulevitch, and Erguang Li

Cleavage of p65/RelA of the NF-B pathway by Chlamydia
PNAS 2007 104: 2933-2938; published online before print February 14 2007, 10.1073/pnas.0608393104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figure]  

Magnus Lundgren and Rolf Bernander

Genome-wide transcription map of an archaeal cell cycle
PNAS 2007 104: 2939-2944; published online before print February 16 2007, 10.1073/pnas.0611333104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Neuroscience

Asif K. Mustafa, Manish Kumar, Balakrishnan Selvakumar, Gary P. H. Ho, Jeffrey T. Ehmsen, Roxanne K. Barrow, L. Mario Amzel, and Solomon H. Snyder

Nitric oxide S-nitrosylates serine racemase, mediating feedback inhibition of D-serine formation
PNAS 2007 104: 2950-2955; published online before print February 9 2007, 10.1073/pnas.0611620104 [Abstract] [Full Text] [Figures Only] [PDF]  

Annalisa Bernareggi, Zulma Dueñas, Jorge Mauricio Reyes-Ruiz, Fabio Ruzzier, and Ricardo Miledi

Properties of glutamate receptors of Alzheimer's disease brain transplanted to frog oocytes
PNAS 2007 104: 2956-2960; published online before print February 14 2007, 10.1073/pnas.0611513104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Table]  

Yael Shrager, Peter J. Bayley, Bruno Bontempi, Ramona O. Hopkins, and Larry R. Squire

Spatial memory and the human hippocampus
PNAS 2007 104: 2961-2966; published online before print February 12 2007, 10.1073/pnas.0611233104 [Abstract] [Full Text] [Figures Only] [PDF]  

Dirk Czesnik, Detlev Schild, Josko Kuduz, and Ivan Manzini

Cannabinoid action in the olfactory epithelium
PNAS 2007 104: 2967-2972; published online before print February 14 2007, 10.1073/pnas.0609067104 [Abstract] [Full Text] [Figures Only] [PDF]  

Marie P. Fogarty, Brian A. Emmenegger, Linda L. Grasfeder, Trudy G. Oliver, and Robert J. Wechsler-Reya

Fibroblast growth factor blocks Sonic hedgehog signaling in neuronal precursors and tumor cells
PNAS 2007 104: 2973-2978; published online before print February 13 2007, 10.1073/pnas.0605770104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Jung-Hyuck Ahn, Thomas McAvoy, Sergey V. Rakhilin, Akinori Nishi, Paul Greengard, and Angus C. Nairn

Protein kinase A activates protein phosphatase 2A by phosphorylation of the B56 subunit
PNAS 2007 104: 2979-2984; published online before print February 14 2007, 10.1073/pnas.0611532104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Gabriele Ugolini, Sara Marinelli, Sonia Covaceuszach, Antonino Cattaneo, and Flaminia Pavone

The function neutralizing anti-TrkA antibody MNAC13 reduces inflammatory and neuropathic pain
PNAS 2007 104: 2985-2990; published online before print February 14 2007, 10.1073/pnas.0611253104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

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Pharmacology

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CORRECTIONS

Correction for Gindulyte et al., The transition state for formation of the peptide bond in the ribosome [Full Text] [PDF]  

Correction for Tang et al., LPS-induced TNF- factor (LITAF)-deficient mice express reduced LPS-induced cytokine: Evidence for LITAF-dependent LPS signaling pathways [Full Text] [PDF]