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THIS WEEK IN PNAS

In This Issue
PNAS 2008 105: 4075-4076. [Full Text] [PDF]  

LETTERS (Online only)

Aurora Grandal d'Anglade and Daniel Fernández Mosquera

Hibernation can also cause high ¹⁵N values in cave bears: A response to Richards et al.
PNAS 2008 105: E14; published online on March 6, 2008, 10.1073/pnas.0800915105 [Extract] [Full Text] [PDF]  

Erik Trinkaus and Michael P. Richards

Reply to Grandal and Fernández: Hibernation can also cause high ¹⁵N values in cave bears
PNAS 2008 105: E15; published online on March 6, 2008, 10.1073/pnas.0801137105 [Extract] [Full Text] [PDF]  

COMMENTARIES

Donald K. Grayson

Holocene underkill
PNAS 2008 105: 4077-4078; published online on March 11, 2008, 10.1073/pnas.0801272105 [Extract] [Full Text] [PDF]  
See companion article on page 4105

Eric L. Berlow, Ulrich Brose, and Neo D. Martinez

The "Goldilocks factor" in food webs
PNAS 2008 105: 4079-4080; published online on March 11, 2008, 10.1073/pnas.0800967105 [Extract] [Full Text] [Figures Only] [PDF]  
See companion article on page 4191

Christopher N. Scanlan, Dennis R. Burton, and Raymond A. Dwek

Making autoantibodies safe
PNAS 2008 105: 4081-4082; published online on March 14, 2008, 10.1073/pnas.0801192105 [Extract] [Full Text] [Figures Only] [PDF]  
See companion article on page 4265

PHYSICAL SCIENCES

Applied Physical Sciences

Choongrak Kim, Mookyung Cheon, Minho Kang, and Iksoo Chang

A simple and exact Laplacian clustering of complex networking phenomena: Application to gene expression profiles
PNAS 2008 105: 4083-4087; published online on March 12, 2008, 10.1073/pnas.0708598105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

Chemistry

Syed Alipayam Rizvi, David S. Courson, Valerie A. Keller, Ronald S. Rock, and Sergey A. Kozmin

The dual mode of action of bistramide A entails severing of filamentous actin and covalent protein modification
PNAS 2008 105: 4088-4092; published online on March 11, 2008, 10.1073/pnas.0710727105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Doug Phanstiel, Justin Brumbaugh, W. Travis Berggren, Kevin Conard, Xuezhu Feng, Mark E. Levenstein, Graeme C. McAlister, James A. Thomson, and Joshua J. Coon

Mass spectrometry identifies and quantifies 74 unique histone H4 isoforms in differentiating human embryonic stem cells
PNAS 2008 105: 4093-4098; published online on March 7, 2008, 10.1073/pnas.0710515105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

L. Lizana, B. Bauer, and O. Orwar

Controlling the rates of biochemical reactions and signaling networks by shape and volume changes
PNAS 2008 105: 4099-4104; published online on March 12, 2008, 10.1073/pnas.0709932105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Supratim Datta, Markos Koutmos, Katherine A. Pattridge, Martha L. Ludwig, and Rowena G. Matthews A disulfide-stabilized conformer of methionine synthase reveals an unexpected role for the histidine ligand of the cobalamin cofactor PNAS 2008 105: 4115-4120; published online on March 10, 2008, 10.1073/pnas.0800329105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

SOCIAL SCIENCES

Anthropology

Psychology

Pejman Sehatpour, Sophie Molholm, Theodore H. Schwartz, Jeannette R. Mahoney, Ashesh D. Mehta, Daniel C. Javitt, Patric K. Stanton, and John J. Foxe

A human intracranial study of long-range oscillatory coherence across a frontal–occipital–hippocampal brain network during visual object processing
PNAS 2008 105: 4399-4404; published online on March 11, 2008, 10.1073/pnas.0708418105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Adrianna C. Jenkins, C. Neil Macrae, and Jason P. Mitchell From the Cover: Repetition suppression of ventromedial prefrontal activity during judgments of self and others PNAS 2008 105: 4507-4512; published online on March 17, 2008, 10.1073/pnas.0708785105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figure] OPEN ACCESS ARTICLE

Social Sciences

William A. V. Clark and Mark Fossett

Understanding the social context of the Schelling segregation model
PNAS 2008 105: 4109-4114; published online on March 11, 2008, 10.1073/pnas.0708155105 [Abstract] [Full Text] [Figures Only] [PDF]  

BIOLOGICAL SCIENCES

Biochemistry

Syed Alipayam Rizvi, David S. Courson, Valerie A. Keller, Ronald S. Rock, and Sergey A. Kozmin

The dual mode of action of bistramide A entails severing of filamentous actin and covalent protein modification
PNAS 2008 105: 4088-4092; published online on March 11, 2008, 10.1073/pnas.0710727105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Doug Phanstiel, Justin Brumbaugh, W. Travis Berggren, Kevin Conard, Xuezhu Feng, Mark E. Levenstein, Graeme C. McAlister, James A. Thomson, and Joshua J. Coon

Mass spectrometry identifies and quantifies 74 unique histone H4 isoforms in differentiating human embryonic stem cells
PNAS 2008 105: 4093-4098; published online on March 7, 2008, 10.1073/pnas.0710515105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

Supratim Datta, Markos Koutmos, Katherine A. Pattridge, Martha L. Ludwig, and Rowena G. Matthews A disulfide-stabilized conformer of methionine synthase reveals an unexpected role for the histidine ligand of the cobalamin cofactor PNAS 2008 105: 4115-4120; published online on March 10, 2008, 10.1073/pnas.0800329105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Satoshi Watanabe, Akiko Kita, Kazuo Kobayashi, and Kunio Miki

Crystal structure of the [2Fe-2S] oxidative-stress sensor SoxR bound to DNA
PNAS 2008 105: 4121-4126; published online on March 11, 2008, 10.1073/pnas.0709188105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Mirjam Lerch-Bader, Carolina Lundin, Hyun Kim, IngMarie Nilsson, and Gunnar von Heijne

Contribution of positively charged flanking residues to the insertion of transmembrane helices into the endoplasmic reticulum
PNAS 2008 105: 4127-4132; published online on March 7, 2008, 10.1073/pnas.0711580105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Sophie Roy, Jeffrey R. Sharom, Caroline Houde, Thomas P. Loisel, John P. Vaillancourt, Wei Shao, Maya Saleh, and Donald W. Nicholson

Confinement of caspase-12 proteolytic activity to autoprocessing
PNAS 2008 105: 4133-4138; published online on March 10, 2008, 10.1073/pnas.0706658105 [Abstract] [Full Text] [Figures Only] [PDF]  

Biophysics

Zsuzsa Ákos, Máté Nagy, and Tamás Vicsek

Comparing bird and human soaring strategies
PNAS 2008 105: 4139-4143; published online on March 3, 2008, 10.1073/pnas.0707711105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Rhiju Das, Madhuri Kudaravalli, Magdalena Jonikas, Alain Laederach, Robert Fong, Jason P. Schwans, David Baker, Joseph A. Piccirilli, Russ B. Altman, and Daniel Herschlag Structural inference of native and partially folded RNA by high-throughput contact mapping PNAS 2008 105: 4144-4149; published online on March 5, 2008, 10.1073/pnas.0709032105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Carolina Carrasco, Milagros Castellanos, Pedro J. de Pablo, and Mauricio G. Mateu

Manipulation of the mechanical properties of a virus by protein engineering
PNAS 2008 105: 4150-4155; published online on March 11, 2008, 10.1073/pnas.0708017105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Surong Zhang, Valeri Metelev, David Tabatadze, Paul C. Zamecnik, and Alexei Bogdanov, Jr

Fluorescence resonance energy transfer in near-infrared fluorescent oligonucleotide probes for detecting protein–DNA interactions
PNAS 2008 105: 4156-4161; published online on March 12, 2008, 10.1073/pnas.0800162105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Cell Biology

Maria Sundvall, Anna Korhonen, Ilkka Paatero, Eugenio Gaudio, Gerry Melino, Carlo M. Croce, Rami I. Aqeilan, and Klaus Elenius

Isoform-specific monoubiquitination, endocytosis, and degradation of alternatively spliced ErbB4 isoforms
PNAS 2008 105: 4162-4167; published online on March 11, 2008, 10.1073/pnas.0708333105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Gregory David, Kathryn B. Grandinetti, Patricia M. Finnerty, Natalie Simpson, Gerald C. Chu, and Ronald A. DePinho

Specific requirement of the chromatin modifier mSin3B in cell cycle exit and cellular differentiation
PNAS 2008 105: 4168-4172; published online on March 10, 2008, 10.1073/pnas.0710285105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Ingrid Pfeifer, Rachel Elsby, Marilyn Fernandez, Paula A. Faria, Daniel R. Nussenzveig, Izidor S. Lossos, Beatriz M. A. Fontoura, W. David Martin, and Glen N. Barber

NFAR-1 and -2 modulate translation and are required for efficient host defense
PNAS 2008 105: 4173-4178; published online on March 12, 2008, 10.1073/pnas.0711222105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

Sumiyasu Ishii, Yasuhiro Kurasawa, Jiemin Wong, and Li-yuan Yu-Lee

Histone deacetylase 3 localizes to the mitotic spindle and is required for kinetochore–microtubule attachment
PNAS 2008 105: 4179-4184; published online on March 6, 2008, 10.1073/pnas.0710140105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Developmental Biology

Takayuki Suzuki, Sean M. Hasso, and John F. Fallon

Unique SMAD1/5/8 activity at the phalanx-forming region determines digit identity
PNAS 2008 105: 4185-4190; published online on March 11, 2008, 10.1073/pnas.0707899105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Ecology

Brian Beckage, Ben Osborne, Daniel G. Gavin, Carolyn Pucko, Thomas Siccama, and Timothy Perkins

A rapid upward shift of a forest ecotone during 40 years of warming in the Green Mountains of Vermont
PNAS 2008 105: 4197-4202; published online on March 11, 2008, 10.1073/pnas.0708921105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Shunichi Takahashi, Spencer Whitney, Shigeru Itoh, Tadashi Maruyama, and Murray Badger

Heat stress causes inhibition of the de novo synthesis of antenna proteins and photobleaching in cultured Symbiodinium
PNAS 2008 105: 4203-4208; published online on March 5, 2008, 10.1073/pnas.0708554105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Environmental Sciences

Roman Stocker, Justin R. Seymour, Azadeh Samadani, Dana E. Hunt, and Martin F. Polz

Rapid chemotactic response enables marine bacteria to exploit ephemeral microscale nutrient patches
PNAS 2008 105: 4209-4214; published online on March 12, 2008, 10.1073/pnas.0709765105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Evolution

Takeshi Sasaki, Hidenori Nishihara, Mika Hirakawa, Koji Fujimura, Mikiko Tanaka, Nobuhiro Kokubo, Chiharu Kimura-Yoshida, Isao Matsuo, Kenta Sumiyama, Naruya Saitou, Tomomi Shimogori, and Norihiro Okada Possible involvement of SINEs in mammalian-specific brain formation PNAS 2008 105: 4220-4225; published online on March 11, 2008, 10.1073/pnas.0709398105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Seth A. Ament, Miguel Corona, Henry S. Pollock, and Gene E. Robinson Insulin signaling is involved in the regulation of worker division of labor in honey bee colonies PNAS 2008 105: 4226-4231; published online on March 12, 2008, 10.1073/pnas.0800630105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Genetics

Tayfun Ozcelik, Nurten Akarsu, Elif Uz, Safak Caglayan, Suleyman Gulsuner, Onur Emre Onat, Meliha Tan, and Uner Tan

Mutations in the very low-density lipoprotein receptor VLDLR cause cerebellar hypoplasia and quadrupedal locomotion in humans
PNAS 2008 105: 4232-4236; published online on March 7, 2008, 10.1073/pnas.0710010105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Lei Sun, Xiaohui Wu, Min Han, Tian Xu, and Yuan Zhuang

A mitotic recombination system for mouse chromosome 17
PNAS 2008 105: 4237-4241; published online on March 6, 2008, 10.1073/pnas.0800798105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Nicolas F. Berbari, Jacqueline S. Lewis, Georgia A. Bishop, Candice C. Askwith, and Kirk Mykytyn

Bardet–Biedl syndrome proteins are required for the localization of G protein-coupled receptors to primary cilia
PNAS 2008 105: 4242-4246; published online on March 11, 2008, 10.1073/pnas.0711027105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Elena Avdievich, Cora Reiss, Stefan J. Scherer, Yongwei Zhang, Sandra M. Maier, Bo Jin, Harry Hou, Jr, Andreas Rosenwald, Hubertus Riedmiller, Raju Kucherlapati, Paula E. Cohen, Winfried Edelmann, and Burkhard Kneitz

Distinct effects of the recurrent Mlh1^G67R mutation on MMR functions, cancer, and meiosis
PNAS 2008 105: 4247-4252; published online on March 12, 2008, 10.1073/pnas.0800276105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

James M. Cheverud, Reinmar Hager, Charles Roseman, Gloria Fawcett, Bing Wang, and Jason B. Wolf

Genomic imprinting effects on adult body composition in mice
PNAS 2008 105: 4253-4258; published online on March 12, 2008, 10.1073/pnas.0706562105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Immunology

Ben J. C. Quah, Vaughan P. Barlow, Virginia McPhun, Klaus I. Matthaei, Mark D. Hulett, and Christopher R. Parish

Bystander B cells rapidly acquire antigen receptors from activated B cells by membrane transfer
PNAS 2008 105: 4259-4264; published online on March 12, 2008, 10.1073/pnas.0800259105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Medical Sciences

Grant D. Barish, Annette R. Atkins, Michael Downes, Peter Olson, Ling-Wa Chong, Mike Nelson, Yuhua Zou, Hoosang Hwang, Heonjoong Kang, Linda Curtiss, Ronald M. Evans, and Chih-Hao Lee

PPAR regulates multiple proinflammatory pathways to suppress atherosclerosis
PNAS 2008 105: 4271-4276; published online on March 12, 2008, 10.1073/pnas.0711875105 [Abstract] [Full Text] [Figures Only] [PDF]  

Yasunori Takata, Joey Liu, Fen Yin, Alan R. Collins, Christopher J. Lyon, Chih-Hao Lee, Annette R. Atkins, Michael Downes, Grant D. Barish, Ronald M. Evans, Willa A. Hsueh, and Rajendra K. Tangirala

PPAR-mediated antiinflammatory mechanisms inhibit angiotensin II-accelerated atherosclerosis
PNAS 2008 105: 4277-4282; published online on March 12, 2008, 10.1073/pnas.0708647105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Siân Jones, Wei-dong Chen, Giovanni Parmigiani, Frank Diehl, Niko Beerenwinkel, Tibor Antal, Arne Traulsen, Martin A. Nowak, Christopher Siegel, Victor E. Velculescu, Kenneth W. Kinzler, Bert Vogelstein, Joseph Willis, and Sanford D. Markowitz

Comparative lesion sequencing provides insights into tumor evolution
PNAS 2008 105: 4283-4288; published online on March 12, 2008, 10.1073/pnas.0712345105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Li Sun, Slobodan Vukicevic, Ramkumarie Baliram, Guozhe Yang, Rebecca Sendak, John McPherson, Ling-Ling Zhu, Jameel Iqbal, Rauf Latif, Arjun Natrajan, Ario Arabi, Kosj Yamoah, Baljit S. Moonga, Yankel Gabet, Terry F. Davies, Itai Bab, Etsuko Abe, Kuber Sampath, and Mone Zaidi

Intermittent recombinant TSH injections prevent ovariectomy-induced bone loss
PNAS 2008 105: 4289-4294; published online on March 10, 2008, 10.1073/pnas.0712395105 [Abstract] [Full Text] [Figures Only] [PDF]  

Beatrice Alexandra Golomb

Acetylcholinesterase inhibitors and Gulf War illnesses
PNAS 2008 105: 4295-4300; published online on March 10, 2008, 10.1073/pnas.0711986105 [Abstract] [Full Text] [PDF] [Supporting Information]  

Nikolay S. Outchkourov, Will Roeffen, Anita Kaan, Josephine Jansen, Adrian Luty, Danielle Schuiffel, Geert Jan van Gemert, Marga van de Vegte-Bolmer, Robert W. Sauerwein, and Hendrik G. Stunnenberg Correctly folded Pfs48/45 protein of Plasmodium falciparum elicits malaria transmission-blocking immunity in mice PNAS 2008 105: 4301-4305; published online on March 10, 2008, 10.1073/pnas.0800459105 [Abstract] [Full Text] [Figures Only] [PDF] OPEN ACCESS ARTICLE

Gemma Tarafa, David Tuck, Daniela Ladner, Mark Topazian, Randall Brand, Carolyn Deters, Victor Moreno, Gabriel Capella, Henry Lynch, Paul Lizardi, and Jose Costa Mutational load distribution analysis yields metrics reflecting genetic instability during pancreatic carcinogenesis PNAS 2008 105: 4306-4311; published online on March 12, 2008, 10.1073/pnas.0708250105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Susan L. Fink, Tessa Bergsbaken, and Brad T. Cookson

Anthrax lethal toxin and Salmonella elicit the common cell death pathway of caspase-1-dependent pyroptosis via distinct mechanisms
PNAS 2008 105: 4312-4317; published online on March 12, 2008, 10.1073/pnas.0707370105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Amanda M. Haidet, Liza Rizo, Chalonda Handy, Priya Umapathi, Amy Eagle, Chris Shilling, Daniel Boue, Paul T. Martin, Zarife Sahenk, Jerry R. Mendell, and Brian K. Kaspar

Long-term enhancement of skeletal muscle mass and strength by single gene administration of myostatin inhibitors
PNAS 2008 105: 4318-4322; published online on March 11, 2008, 10.1073/pnas.0709144105 [Abstract] [Full Text] [Figures Only] [PDF]  

Igor Feldman, Andrey Rzhetsky, and Dennis Vitkup

Network properties of genes harboring inherited disease mutations
PNAS 2008 105: 4323-4328; published online on March 7, 2008, 10.1073/pnas.0701722105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Lynne-Marie Postovit, Naira V. Margaryan, Elisabeth A. Seftor, Dawn A. Kirschmann, Alina Lipavsky, William W. Wheaton, Daniel E. Abbott, Richard E. B. Seftor, and Mary J. C. Hendrix

Human embryonic stem cell microenvironment suppresses the tumorigenic phenotype of aggressive cancer cells
PNAS 2008 105: 4329-4334; published online on March 11, 2008, 10.1073/pnas.0800467105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Rabindra Tirouvanziam, Yael Gernez, Carol K. Conrad, Richard B. Moss, Iris Schrijver, Colleen E. Dunn, Zoe A. Davies, Leonore A. Herzenberg, and Leonard A. Herzenberg

Profound functional and signaling changes in viable inflammatory neutrophils homing to cystic fibrosis airways
PNAS 2008 105: 4335-4339; published online on March 11, 2008, 10.1073/pnas.0712386105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Bert Gold, Tomas Kirchhoff, Stefan Stefanov, James Lautenberger, Agnes Viale, Judy Garber, Eitan Friedman, Steven Narod, Adam B. Olshen, Peter Gregersen, Kristi Kosarin, Adam Olsh, Julie Bergeron, Nathan A. Ellis, Robert J. Klein, Andrew G. Clark, Larry Norton, Michael Dean, Jeff Boyd, and Kenneth Offit Genome-wide association study provides evidence for a breast cancer risk locus at 6q22.33 PNAS 2008 105: 4340-4345; published online on March 7, 2008, 10.1073/pnas.0800441105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Microbiology

Guifang Chen, Xuemin Guo, Fengxiang Lv, Yihui Xu, and Guangxia Gao

p72 DEAD box RNA helicase is required for optimal function of the zinc-finger antiviral protein
PNAS 2008 105: 4352-4357; published online on March 11, 2008, 10.1073/pnas.0712276105 [Abstract] [Full Text] [Figures Only] [PDF]  

Marios Giannakis, Swaine L. Chen, Sherif M. Karam, Lars Engstrand, and Jeffrey I. Gordon Helicobacter pylori evolution during progression from chronic atrophic gastritis to gastric cancer and its impact on gastric stem cells PNAS 2008 105: 4358-4363; published online on March 10, 2008, 10.1073/pnas.0800668105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Andreas Rolfs, Wagner R. Montor, Sang Sun Yoon, Yanhui Hu, Bhupinder Bhullar, Fontina Kelley, Seamus McCarron, Daniel A. Jepson, Binghua Shen, Elena Taycher, Stephanie E. Mohr, Dongmei Zuo, Janice Williamson, John Mekalanos, and Joshua LaBaer

Production and sequence validation of a complete full length ORF collection for the pathogenic bacterium Vibrio cholerae
PNAS 2008 105: 4364-4369; published online on March 12, 2008, 10.1073/pnas.0712049105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Rodney S. Russell, Jean-Christophe Meunier, Shingo Takikawa, Kristina Faulk, Ronald E. Engle, Jens Bukh, Robert H. Purcell, and Suzanne U. Emerson

Advantages of a single-cycle production assay to study cell culture-adaptive mutations of hepatitis C virus
PNAS 2008 105: 4370-4375; published online on March 11, 2008, 10.1073/pnas.0800422105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Amit K. Pandey and Christopher M. Sassetti

Mycobacterial persistence requires the utilization of host cholesterol
PNAS 2008 105: 4376-4380; published online on March 11, 2008, 10.1073/pnas.0711159105 [Abstract] [Full Text] [Figures Only] [PDF]  

David Jackson, Md. Jaber Hossain, Danielle Hickman, Daniel R. Perez, and Robert A. Lamb A new influenza virus virulence determinant: The NS1 protein four C-terminal residues modulate pathogenicity PNAS 2008 105: 4381-4386; published online on March 11, 2008, 10.1073/pnas.0800482105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Mikael R. Andersen, Wanwipa Vongsangnak, Gianni Panagiotou, Margarita P. Salazar, Linda Lehmann, and Jens Nielsen A trispecies Aspergillus microarray: Comparative transcriptomics of three Aspergillus species PNAS 2008 105: 4387-4392; published online on March 10, 2008, 10.1073/pnas.0709964105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Jan-Willem Veening, Eric J. Stewart, Thomas W. Berngruber, François Taddei, Oscar P. Kuipers, and Leendert W. Hamoen Bet-hedging and epigenetic inheritance in bacterial cell development PNAS 2008 105: 4393-4398; published online on March 6, 2008, 10.1073/pnas.0700463105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Neuroscience

Pejman Sehatpour, Sophie Molholm, Theodore H. Schwartz, Jeannette R. Mahoney, Ashesh D. Mehta, Daniel C. Javitt, Patric K. Stanton, and John J. Foxe

A human intracranial study of long-range oscillatory coherence across a frontal–occipital–hippocampal brain network during visual object processing
PNAS 2008 105: 4399-4404; published online on March 11, 2008, 10.1073/pnas.0708418105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Ali Salahpour, Amy J. Ramsey, Ivan O. Medvedev, Brian Kile, Tatyana D. Sotnikova, Ericka Holmstrand, Valentina Ghisi, Peter J. Nicholls, Ling Wong, Karen Murphy, Susan R. Sesack, R. Mark Wightman, Raul R. Gainetdinov, and Marc G. Caron

Increased amphetamine-induced hyperactivity and reward in mice overexpressing the dopamine transporter
PNAS 2008 105: 4405-4410; published online on March 17, 2008, 10.1073/pnas.0707646105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] [Supporting Information]  

Samuel Andrew Hires, Yongling Zhu, and Roger Y. Tsien Optical measurement of synaptic glutamate spillover and reuptake by linker optimized glutamate-sensitive fluorescent reporters PNAS 2008 105: 4411-4416; published online on March 10, 2008, 10.1073/pnas.0712008105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Christian Leibold, Anja Gundlfinger, Robert Schmidt, Kay Thurley, Dietmar Schmitz, and Richard Kempter

Temporal compression mediated by short-term synaptic plasticity
PNAS 2008 105: 4417-4422; published online on March 12, 2008, 10.1073/pnas.0708711105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Xiaoming Zhou and Michael M. Merzenich

Enduring effects of early structured noise exposure on temporal modulation in the primary auditory cortex
PNAS 2008 105: 4423-4428; published online on March 10, 2008, 10.1073/pnas.0800009105 [Abstract] [Full Text] [Figures Only] [PDF]  

Soong Ho Kim, Julie A. Markham, Ivan Jeanne Weiler, and William T. Greenough

Aberrant early-phase ERK inactivation impedes neuronal function in fragile X syndrome
PNAS 2008 105: 4429-4434; published online on March 10, 2008, 10.1073/pnas.0800257105 [Abstract] [Full Text] [Figures Only] [PDF]  

Yonatan M. Kupchik, Grigory Rashkovan, Lily Ohana, Tal Keren-Raifman, Nathan Dascal, Hanna Parnas, and Itzchak Parnas

Molecular mechanisms that control initiation and termination of physiological depolarization-evoked transmitter release
PNAS 2008 105: 4435-4440; published online on March 7, 2008, 10.1073/pnas.0708540105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Winnie S. Liang, Eric M. Reiman, Jon Valla, Travis Dunckley, Thomas G. Beach, Andrew Grover, Tracey L. Niedzielko, Lonnie E. Schneider, Diego Mastroeni, Richard Caselli, Walter Kukull, John C. Morris, Christine M. Hulette, Donald Schmechel, Joseph Rogers, and Dietrich A. Stephan

Alzheimer's disease is associated with reduced expression of energy metabolism genes in posterior cingulate neurons
PNAS 2008 105: 4441-4446; published online on March 10, 2008, 10.1073/pnas.0709259105 [Abstract] [Full Text] [Figures Only] [PDF]  

Rebecca F. Schwarzlose, Jascha D. Swisher, Sabin Dang, and Nancy Kanwisher

The distribution of category and location information across object-selective regions in human visual cortex
PNAS 2008 105: 4447-4452; published online on March 7, 2008, 10.1073/pnas.0800431105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Xiaobing Chen, Christine Winters, Rita Azzam, Xiang Li, James A. Galbraith, Richard D. Leapman, and Thomas S. Reese

Organization of the core structure of the postsynaptic density
PNAS 2008 105: 4453-4458; published online on March 7, 2008, 10.1073/pnas.0800897105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Maria F. Arteaga, Tatjana Coric, Christoph Straub, and Cecilia M. Canessa A brain-specific SGK1 splice isoform regulates expression of ASIC1 in neurons PNAS 2008 105: 4459-4464; published online on March 11, 2008, 10.1073/pnas.0800958105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figure] OPEN ACCESS ARTICLE

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