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THIS WEEK IN PNAS

In This Issue
PNAS 2008 105: 2753-2754. [Full Text] [PDF]  

EDITORIAL

Randy Schekman

Charting the course for PNAS
PNAS 2008 105: 2755-2756; published online on February 1, 2008, 10.1073/pnas.0800528105 [Extract] [Full Text] [Figures Only] [PDF]  

LETTERS (Online only)

Razvan Tudor Radulescu

Going beyond the genetic view of cancer
PNAS 2008 105: E12; published online on February 11, 2008, 10.1073/pnas.0712232105 [Extract] [Full Text] [PDF]  

COMMENTARIES

Peter Kareiva

Ominous trends in nature recreation
PNAS 2008 105: 2757-2758; published online on February 19, 2008, 10.1073/pnas.0800474105 [Extract] [Full Text] [PDF]  
See companion article on page 2295 in issue 7 of volume 105

Alan R. Davidson

A folding space odyssey
PNAS 2008 105: 2759-2760; published online on February 19, 2008, 10.1073/pnas.0800030105 [Extract] [Full Text] [Figures Only] [PDF]  
See companion article on page 2343 in issue 7 of volume 105

W. John Kress and David L. Erickson

DNA barcodes: Genes, genomics, and bioinformatics
PNAS 2008 105: 2761-2762; published online on February 19, 2008, 10.1073/pnas.0800476105 [Extract] [Full Text] [Figures Only] [PDF]  
See companion article on page 2923

PROFILES

Nick Zagorski

Profile of Randy Schekman: Reflections on his first year as PNAS Editor-in-Chief
PNAS 2008 105: 2763-2765; published online on February 20, 2008, 10.1073/pnas.0610781105 [Extract] [Full Text] [Figures Only] [PDF]  

PHYSICAL SCIENCES

Applied Mathematics

Chemistry

Edgar R. Wood, Lisa M. Shewchuk, Byron Ellis, Perry Brignola, Ronald L. Brashear, Thomas R. Caferro, Scott H. Dickerson, Hamilton D. Dickson, Kelly H. Donaldson, Michael Gaul, Robert J. Griffin, Anne M. Hassell, Barry Keith, Robert Mullin, Kimberly G. Petrov, Michael J. Reno, David W. Rusnak, Sarva M. Tadepalli, John C. Ulrich, Craig D. Wagner, Dana E. Vanderwall, Alex G. Waterson, Jon D. Williams, Wendy L. White, and David E. Uehling

6-Ethynylthieno[3,2-d]- and 6-ethynylthieno[2,3-d]pyrimidin-4-anilines as tunable covalent modifiers of ErbB kinases
PNAS 2008 105: 2773-2778; published online on February 19, 2008, 10.1073/pnas.0708281105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Nathan D. Shapiro and F. Dean Toste

Synthesis and structural characterization of isolable phosphine coinage metal -complexes
PNAS 2008 105: 2779-2782; published online on February 19, 2008, 10.1073/pnas.0710500105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Michael D. Irwin, D. Bruce Buchholz, Alexander W. Hains, Robert P. H. Chang, and Tobin J. Marks

p-Type semiconducting nickel oxide as an efficiency-enhancing anode interfacial layer in polymer bulk-heterojunction solar cells
PNAS 2008 105: 2783-2787; published online on February 19, 2008, 10.1073/pnas.0711990105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Geology

BIOLOGICAL SCIENCES

Applied Biological Sciences

Nathaniel P. Chongsiriwatana, James A. Patch, Ann M. Czyzewski, Michelle T. Dohm, Andrey Ivankin, David Gidalevitz, Ronald N. Zuckermann, and Annelise E. Barron

Peptoids that mimic the structure, function, and mechanism of helical antimicrobial peptides
PNAS 2008 105: 2794-2799; published online on February 19, 2008, 10.1073/pnas.0708254105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Biochemistry

Edgar R. Wood, Lisa M. Shewchuk, Byron Ellis, Perry Brignola, Ronald L. Brashear, Thomas R. Caferro, Scott H. Dickerson, Hamilton D. Dickson, Kelly H. Donaldson, Michael Gaul, Robert J. Griffin, Anne M. Hassell, Barry Keith, Robert Mullin, Kimberly G. Petrov, Michael J. Reno, David W. Rusnak, Sarva M. Tadepalli, John C. Ulrich, Craig D. Wagner, Dana E. Vanderwall, Alex G. Waterson, Jon D. Williams, Wendy L. White, and David E. Uehling

6-Ethynylthieno[3,2-d]- and 6-ethynylthieno[2,3-d]pyrimidin-4-anilines as tunable covalent modifiers of ErbB kinases
PNAS 2008 105: 2773-2778; published online on February 19, 2008, 10.1073/pnas.0708281105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Aravind Srinivasan, Karthik Viswanathan, Rahul Raman, Aarthi Chandrasekaran, S. Raguram, Terrence M. Tumpey, V. Sasisekharan, and Ram Sasisekharan From the Cover: Quantitative biochemical rationale for differences in transmissibility of 1918 pandemic influenza A viruses PNAS 2008 105: 2800-2805; published online on February 19, 2008, 10.1073/pnas.0711963105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures] OPEN ACCESS ARTICLE

Ki Seog Lee, Daniela Bumbaca, Jeffrey Kosman, Peter Setlow, and Mark J. Jedrzejas

Structure of a protein–DNA complex essential for DNA protection in spores of Bacillus species
PNAS 2008 105: 2806-2811; published online on February 19, 2008, 10.1073/pnas.0708244105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Johannes M. Aerts, Johanna E. Groener, Sijmen Kuiper, Wilma E. Donker-Koopman, Anneke Strijland, Roelof Ottenhoff, Cindy van Roomen, Mina Mirzaian, Frits A. Wijburg, Gabor E. Linthorst, Anouk C. Vedder, Saskia M. Rombach, Josanne Cox-Brinkman, Pentti Somerharju, Rolf G. Boot, Carla E. Hollak, Roscoe O. Brady, and Ben J. Poorthuis

Elevated globotriaosylsphingosine is a hallmark of Fabry disease
PNAS 2008 105: 2812-2817; published online on February 19, 2008, 10.1073/pnas.0712309105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Rigoberto Rios-Estepa, Glenn W. Turner, James M. Lee, Rodney B. Croteau, and B. Markus Lange

A systems biology approach identifies the biochemical mechanisms regulating monoterpenoid essential oil composition in peppermint
PNAS 2008 105: 2818-2823; published online on February 19, 2008, 10.1073/pnas.0712314105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Shiamalee Perumal, Olga Antipova, and Joseph P. R. O. Orgel Collagen fibril architecture, domain organization, and triple-helical conformation govern its proteolysis PNAS 2008 105: 2824-2829; published online on February 14, 2008, 10.1073/pnas.0710588105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Daisuke Hishikawa, Hideo Shindou, Saori Kobayashi, Hiroki Nakanishi, Ryo Taguchi, and Takao Shimizu Discovery of a lysophospholipid acyltransferase family essential for membrane asymmetry and diversity PNAS 2008 105: 2830-2835; published online on February 20, 2008, 10.1073/pnas.0712245105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Biophysics

Thanashan Rajakulendran, Malha Sahmi, Igor Kurinov, Mike Tyers, Marc Therrien, and Frank Sicheri

CNK and HYP form a discrete dimer by their SAM domains to mediate RAF kinase signaling
PNAS 2008 105: 2836-2841; published online on February 19, 2008, 10.1073/pnas.0709705105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

D. Horinek, A. Serr, M. Geisler, T. Pirzer, U. Slotta, S. Q. Lud, J. A. Garrido, T. Scheibel, T. Hugel, and R. R. Netz

Peptide adsorption on a hydrophobic surface results from an interplay of solvation, surface, and intrapeptide forces
PNAS 2008 105: 2842-2847; published online on February 20, 2008, 10.1073/pnas.0707879105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Allison D. Dupuy and Donald M. Engelman

Protein area occupancy at the center of the red blood cell membrane
PNAS 2008 105: 2848-2852; published online on February 19, 2008, 10.1073/pnas.0712379105 [Abstract] [Full Text] [Figures Only] [PDF]  

Cell Biology

Terrence Town, Joshua J. Breunig, Matthew R. Sarkisian, Charalampos Spilianakis, Albert E. Ayoub, Xiuxin Liu, Anthony F. Ferrandino, A. Rachel Gallagher, Ming O. Li, Pasko Rakic, and Richard A. Flavell

The stumpy gene is required for mammalian ciliogenesis
PNAS 2008 105: 2853-2858; published online on February 19, 2008, 10.1073/pnas.0712385105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Matilde Colella, Francesca Grisan, Valerie Robert, Jay D. Turner, Andrew P. Thomas, and Tullio Pozzan

Ca²⁺ oscillation frequency decoding in cardiac cell hypertrophy: Role of calcineurin/NFAT as Ca²⁺ signal integrators
PNAS 2008 105: 2859-2864; published online on February 19, 2008, 10.1073/pnas.0712316105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

A. Mario Marcondes, Andrew J. Mhyre, Derek L. Stirewalt, Soo-Hyun Kim, Charles A. Dinarello, and H. Joachim Deeg

Dysregulation of IL-32 in myelodysplastic syndrome and chronic myelomonocytic leukemia modulates apoptosis and impairs NK function
PNAS 2008 105: 2865-2870; published online on February 19, 2008, 10.1073/pnas.0712391105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Legong Li, Kun Liu, Yong Hu, Dongping Li, and Sheng Luan

Single mutations convert an outward K⁺ channel into an inward K⁺ channel
PNAS 2008 105: 2871-2876; published online on February 19, 2008, 10.1073/pnas.0712349105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Carmen Citterio, Alessandro Vichi, Gustavo Pacheco-Rodriguez, Angel M. Aponte, Joel Moss, and Martha Vaughan

Unfolded protein response and cell death after depletion of brefeldin A-inhibited guanine nucleotide-exchange protein GBF1
PNAS 2008 105: 2877-2882; published online on February 14, 2008, 10.1073/pnas.0712224105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

W. E. Lowry, L. Richter, R. Yachechko, A. D. Pyle, J. Tchieu, R. Sridharan, A. T. Clark, and K. Plath

Generation of human induced pluripotent stem cells from dermal fibroblasts
PNAS 2008 105: 2883-2888; published online on February 15, 2008, 10.1073/pnas.0711983105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Qiang Wang, Yan Chun Li, Jinhua Wang, Juan Kong, Yuchen Qi, Richard J. Quigg, and Xinmin Li

miR-17-92 cluster accelerates adipocyte differentiation by negatively regulating tumor-suppressor Rb2/p130
PNAS 2008 105: 2889-2894; published online on February 19, 2008, 10.1073/pnas.0800178105 [Abstract] [Full Text] [Figures Only] [PDF]  

Yanhong Liao, Christian Erxleben, Joel Abramowitz, Veit Flockerzi, Michael Xi Zhu, David L. Armstrong, and Lutz Birnbaumer

Functional interactions among Orai1, TRPCs, and STIM1 suggest a STIM-regulated heteromeric Orai/TRPC model for SOCE/Icrac channels
PNAS 2008 105: 2895-2900; published online on February 19, 2008, 10.1073/pnas.0712288105 [Abstract] [Full Text] [Figures Only] [PDF]  

Developmental Biology

Dmitri Papatsenko and Michael S. Levine

Dual regulation by the Hunchback gradient in the Drosophila embryo
PNAS 2008 105: 2901-2906; published online on February 19, 2008, 10.1073/pnas.0711941105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Teddy Fauquier, Karine Rizzoti, Mehul Dattani, Robin Lovell-Badge, and Iain C. A. F. Robinson

SOX2-expressing progenitor cells generate all of the major cell types in the adult mouse pituitary gland
PNAS 2008 105: 2907-2912; published online on February 15, 2008, 10.1073/pnas.0707886105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Lucile Ryckebusch, Zengxin Wang, Nicolas Bertrand, Song-Chang Lin, Xuan Chi, Robert Schwartz, Stéphane Zaffran, and Karen Niederreither

Retinoic acid deficiency alters second heart field formation
PNAS 2008 105: 2913-2918; published online on February 19, 2008, 10.1073/pnas.0712344105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Ecology

Peter A. Biro and John R. Post

Rapid depletion of genotypes with fast growth and bold personality traits from harvested fish populations
PNAS 2008 105: 2919-2922; published online on February 25, 2008, 10.1073/pnas.0708159105 [Abstract] [Full Text] [Figures Only] [PDF]  

Renaud Lahaye, Michelle van der Bank, Diego Bogarin, Jorge Warner, Franco Pupulin, Guillaume Gigot, Olivier Maurin, Sylvie Duthoit, Timothy G. Barraclough, and Vincent Savolainen From the Cover: DNA barcoding the floras of biodiversity hotspots PNAS 2008 105: 2923-2928; published online on February 7, 2008, 10.1073/pnas.0709936105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE   See Commentary on page 2761

Colin E. Studds, T. Kurt Kyser, and Peter P. Marra

Natal dispersal driven by environmental conditions interacting across the annual cycle of a migratory songbird
PNAS 2008 105: 2929-2933; published online on February 19, 2008, 10.1073/pnas.0710732105 [Abstract] [Full Text] [Figures Only] [PDF]  

Evolution

Kai Tan, Hoda Feizi, Colin Luo, Stephanie H. Fan, Timothy Ravasi, and Trey G. Ideker

A systems approach to delineate functions of paralogous transcription factors: Role of the Yap family in the DNA damage response
PNAS 2008 105: 2934-2939; published online on February 19, 2008, 10.1073/pnas.0708670105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Nicholas C. Manoukis, Jeffrey R. Powell, Mahamoudou B. Touré, Adama Sacko, Frances E. Edillo, Mamadou B. Coulibaly, Sekou F. Traoré, Charles E. Taylor, and Nora J. Besansky

A test of the chromosomal theory of ecotypic speciation in Anopheles gambiae
PNAS 2008 105: 2940-2945; published online on February 14, 2008, 10.1073/pnas.0709806105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Alysha M. Heimberg, Lorenzo F. Sempere, Vanessa N. Moy, Philip C. J. Donoghue, and Kevin J. Peterson

MicroRNAs and the advent of vertebrate morphological complexity
PNAS 2008 105: 2946-2950; published online on February 14, 2008, 10.1073/pnas.0712259105 [Abstract] [Full Text] [Figures Only] [PDF]  

Susan E. Evans, Marc E. H. Jones, and David W. Krause

A giant frog with South American affinities from the Late Cretaceous of Madagascar
PNAS 2008 105: 2951-2956; published online on February 19, 2008, 10.1073/pnas.0707599105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Mar Marzo, Marta Puig, and Alfredo Ruiz

The Foldback-like element Galileo belongs to the P superfamily of DNA transposons and is widespread within the Drosophila genus
PNAS 2008 105: 2957-2962; published online on February 19, 2008, 10.1073/pnas.0712110105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Genetics

Todd A. Sangster, Neeraj Salathia, Soledad Undurraga, Ron Milo, Kurt Schellenberg, Susan Lindquist, and Christine Queitsch

HSP90 affects the expression of genetic variation and developmental stability in quantitative traits
PNAS 2008 105: 2963-2968; published online on February 19, 2008, 10.1073/pnas.0712200105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Todd A. Sangster, Neeraj Salathia, Hana N. Lee, Etsuko Watanabe, Kurt Schellenberg, Keith Morneau, Hui Wang, Soledad Undurraga, Christine Queitsch, and Susan Lindquist

HSP90-buffered genetic variation is common in Arabidopsis thaliana
PNAS 2008 105: 2969-2974; published online on February 19, 2008, 10.1073/pnas.0712210105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Monique Floer, Gene O. Bryant, and Mark Ptashne HSP90/70 chaperones are required for rapid nucleosome removal upon induction of the GAL genes of yeast PNAS 2008 105: 2975-2980; published online on February 19, 2008, 10.1073/pnas.0800053105 [Abstract] [Full Text] [Figures Only] [PDF] OPEN ACCESS ARTICLE

Immunology

Curtis P. McMurtrey, Alina Lelic, Paolo Piazza, Ayan K. Chakrabarti, Eric J. Yablonsky, Angela Wahl, Wilfried Bardet, Annette Eckerd, Robert L. Cook, Rachael Hess, Rico Buchli, Mark Loeb, Charles R. Rinaldo, Jonathan Bramson, and William H. Hildebrand

Epitope discovery in West Nile virus infection: Identification and immune recognition of viral epitopes
PNAS 2008 105: 2981-2986; published online on February 25, 2008, 10.1073/pnas.0711874105 [Abstract] [Full Text] [Figures Only] [PDF]  

Christos Tsatsanis, Katerina Vaporidi, Vassiliki Zacharioudaki, Ariadne Androulidaki, Yuri Sykulev, Andrew N. Margioris, and Philip N. Tsichlis

Tpl2 and ERK transduce antiproliferative T cell receptor signals and inhibit transformation of chronically stimulated T cells
PNAS 2008 105: 2987-2992; published online on February 19, 2008, 10.1073/pnas.0708381104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Hiroshi Watarai, Etsuko Sekine, Sayo Inoue, Ryusuke Nakagawa, Tsuneyasu Kaisho, and Masaru Taniguchi

PDC-TREM, a plasmacytoid dendritic cell-specific receptor, is responsible for augmented production of type I interferon
PNAS 2008 105: 2993-2998; published online on February 19, 2008, 10.1073/pnas.0710351105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Thomas Calzascia, Marc Pellegrini, Albert Lin, Kristine M. Garza, Alisha R. Elford, Arda Shahinian, Pamela S. Ohashi, and Tak W. Mak

CD4 T cells, lymphopenia, and IL-7 in a multistep pathway to autoimmunity
PNAS 2008 105: 2999-3004; published online on February 14, 2008, 10.1073/pnas.0712135105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

F. Stephen Hodi, Marcus Butler, Darryl A. Oble, Michael V. Seiden, Frank G. Haluska, Andrea Kruse, Suzanne MacRae, Marybeth Nelson, Christine Canning, Israel Lowy, Alan Korman, David Lautz, Sara Russell, Michael T. Jaklitsch, Nikhil Ramaiya, Teresa C. Chen, Donna Neuberg, James P. Allison, Martin C. Mihm, and Glenn Dranoff

Immunologic and clinical effects of antibody blockade of cytotoxic T lymphocyte-associated antigen 4 in previously vaccinated cancer patients
PNAS 2008 105: 3005-3010; published online on February 19, 2008, 10.1073/pnas.0712237105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

David Yin-wei Lin, Yoshimasa Tanaka, Masashi Iwasaki, Apostolos G. Gittis, Hua-Poo Su, Bunzo Mikami, Taku Okazaki, Tasuku Honjo, Nagahiro Minato, and David N. Garboczi

The PD-1/PD-L1 complex resembles the antigen-binding Fv domains of antibodies and T cell receptors
PNAS 2008 105: 3011-3016; published online on February 14, 2008, 10.1073/pnas.0712278105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Changlin Li, Baoxue Ge, Matthew Nicotra, Joel N. H. Stern, Hernan D. Kopcow, Xi Chen, and Jack L. Strominger

JNK MAP kinase activation is required for MTOC and granule polarization in NKG2D-mediated NK cell cytotoxicity
PNAS 2008 105: 3017-3022; published online on February 19, 2008, 10.1073/pnas.0712310105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Chuan-Jin Wu and Jonathan D. Ashwell

NEMO recognition of ubiquitinated Bcl10 is required for T cell receptor-mediated NF-B activation
PNAS 2008 105: 3023-3028; published online on February 19, 2008, 10.1073/pnas.0712313105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Ming Lee Lin, Yifan Zhan, Anna I. Proietto, Sandro Prato, Li Wu, William R. Heath, Jose A. Villadangos, and Andrew M. Lew

Selective suicide of cross-presenting CD8⁺ dendritic cells by cytochrome c injection shows functional heterogeneity within this subset
PNAS 2008 105: 3029-3034; published online on February 12, 2008, 10.1073/pnas.0712394105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Silke F. Fischer, Gabrielle T. Belz, and Andreas Strasser

BH3-only protein Puma contributes to death of antigen-specific T cells during shutdown of an immune response to acute viral infection
PNAS 2008 105: 3035-3040; published online on February 19, 2008, 10.1073/pnas.0706913105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Medical Sciences

Tetsuya Fukuda, Liguang Chen, Tomoyuki Endo, Li Tang, Desheng Lu, Januario E. Castro, George F. Widhopf, II, Laura Z. Rassenti, Mark J. Cantwell, Charles E. Prussak, Dennis A. Carson, and Thomas J. Kipps

Antisera induced by infusions of autologous Ad-CD154-leukemia B cells identify ROR1 as an oncofetal antigen and receptor for Wnt5a
PNAS 2008 105: 3047-3052; published online on February 19, 2008, 10.1073/pnas.0712148105 [Abstract] [Full Text] [Figures Only] [PDF]  

Sungjin Kim, John B. Sunwoo, Liping Yang, Taewoong Choi, Yun-Jeong Song, Anthony R. French, Anna Vlahiotis, Jay F. Piccirillo, Marina Cella, Marco Colonna, Thalachallour Mohanakumar, Katharine C. Hsu, Bo Dupont, and Wayne M. Yokoyama

HLA alleles determine differences in human natural killer cell responsiveness and potency
PNAS 2008 105: 3053-3058; published online on February 19, 2008, 10.1073/pnas.0712229105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Jens Fielitz, Mi-Sung Kim, John M. Shelton, Xiaoxia Qi, Joseph A. Hill, James A. Richardson, Rhonda Bassel-Duby, and Eric N. Olson

Requirement of protein kinase D1 for pathological cardiac remodeling
PNAS 2008 105: 3059-3063; published online on February 14, 2008, 10.1073/pnas.0712265105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Microbiology

Jennifer A. Philips, Maura C. Porto, Hui Wang, Eric J. Rubin, and Norbert Perrimon

ESCRT factors restrict mycobacterial growth
PNAS 2008 105: 3070-3075; published online on February 19, 2008, 10.1073/pnas.0707206105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Ariel B. Lindner, Richard Madden, Alice Demarez, Eric J. Stewart, and François Taddei Asymmetric segregation of protein aggregates is associated with cellular aging and rejuvenation PNAS 2008 105: 3076-3081; published online on February 19, 2008, 10.1073/pnas.0708931105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Glenn Dulla and Steven E. Lindow

Quorum size of Pseudomonas syringae is small and dictated by water availability on the leaf surface
PNAS 2008 105: 3082-3087; published online on February 19, 2008, 10.1073/pnas.0711723105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Guofeng Cheng, Ana Montero, Pablo Gastaminza, Christina Whitten-Bauer, Stefan F. Wieland, Masanori Isogawa, Brenda Fredericksen, Suganya Selvarajah, Philippe A. Gallay, M. Reza Ghadiri, and Francis V. Chisari

A virocidal amphipathic -helical peptide that inhibits hepatitis C virus infection in vitro
PNAS 2008 105: 3088-3093; published online on February 19, 2008, 10.1073/pnas.0712380105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Claudia Mack, Albert Sickmann, David Lembo, and Wolfram Brune

Inhibition of proinflammatory and innate immune signaling pathways by a cytomegalovirus RIP1-interacting protein
PNAS 2008 105: 3094-3099; published online on February 19, 2008, 10.1073/pnas.0800168105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Kalai Mathee, Giri Narasimhan, Camilo Valdes, Xiaoyun Qiu, Jody M. Matewish, Michael Koehrsen, Antonis Rokas, Chandri N. Yandava, Reinhard Engels, Erliang Zeng, Raquel Olavarietta, Melissa Doud, Roger S. Smith, Philip Montgomery, Jared R. White, Paul A. Godfrey, Chinnappa Kodira, Bruce Birren, James E. Galagan, and Stephen Lory Dynamics of Pseudomonas aeruginosa genome evolution PNAS 2008 105: 3100-3105; published online on February 19, 2008, 10.1073/pnas.0711982105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Neuroscience

Hiroki Yasuda, Yan Huang, and Tadaharu Tsumoto

Regulation of excitability and plasticity by endocannabinoids and PKA in developing hippocampus
PNAS 2008 105: 3106-3111; published online on February 19, 2008, 10.1073/pnas.0708349105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Jee Young Sung, Olivia Engmann, Merilee A. Teylan, Angus C. Nairn, Paul Greengard, and Yong Kim

WAVE1 controls neuronal activity-induced mitochondrial distribution in dendritic spines
PNAS 2008 105: 3112-3116; published online on February 14, 2008, 10.1073/pnas.0712180105 [Abstract] [Full Text] [Figures Only] [PDF]  

Eriko Fujita, Yuko Tanabe, Akira Shiota, Masatsugu Ueda, Kiyotaka Suwa, Mariko Y. Momoi, and Takashi Momoi

Ultrasonic vocalization impairment of Foxp2 (R552H) knockin mice related to speech-language disorder and abnormality of Purkinje cells
PNAS 2008 105: 3117-3122; published online on February 19, 2008, 10.1073/pnas.0712298105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Natalia Bastrikova, Gregory A. Gardner, Jeff M. Reece, Andreas Jeromin, and Serena M. Dudek

Synapse elimination accompanies functional plasticity in hippocampal neurons
PNAS 2008 105: 3123-3127; published online on February 19, 2008, 10.1073/pnas.0800027105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Pharmacology

Qiaojie Xiong, Haiyan Sun, Yangming Zhang, Fajun Nan, and Min Li

Combinatorial augmentation of voltage-gated KCNQ potassium channels by chemical openers
PNAS 2008 105: 3128-3133; published online on February 12, 2008, 10.1073/pnas.0712256105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Physiology

Robert A. Fenton, Hanne B. Moeller, Jason D. Hoffert, Ming-Jiun Yu, Søren Nielsen, and Mark A. Knepper

Acute regulation of aquaporin-2 phosphorylation at Ser-264 by vasopressin
PNAS 2008 105: 3134-3139; published online on February 19, 2008, 10.1073/pnas.0712338105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

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CORRECTIONS

Correction for Lawrence et al., Land Change Science Special Feature: Ecological feedbacks following deforestation create the potential for a catastrophic ecosystem shift in tropical dry forest [Full Text] [Figures Only] [PDF]