COLLOQUIUM:
Papers from an NAS Colloquium on Genetic Engineering of Viruses and of Virus Vectors

Peter Palese and Bernard Roizman

Genetic engineering of viruses and of virus vectors: A preface
PNAS 1996 93: 11287-11287. [Abstract] [PDF]  

R. Michael Linden, Peter Ward, Catherine Giraud, Ernest Winocour, and Kenneth I. Berns

Site-specific integration by adeno-associated virus
PNAS 1996 93: 11288-11294. [Abstract] [PDF]  

Mary Moore, Nobuo Horikoshi, and Thomas Shenk

Oncogenic potential of the adenovirus E4orf6 protein
PNAS 1996 93: 11295-11301. [Abstract] [PDF]  

Manuel Caruso, Khiem Pham-Nguyen, Yok-Lam Kwong, Bisong Xu, Ken-Ichiro Kosai, Milton Finegold, Savio L. C. Woo, and Shu-Hsia Chen

Adenovirus-mediated interleukin-12 gene therapy for metastatic colon carcinoma
PNAS 1996 93: 11302-11306. [Abstract] [PDF]  

Bernard Roizman

The function of herpes simplex virus genes: A primer for genetic engineering of novel vectors
PNAS 1996 93: 11307-11312. [Abstract] [PDF]  

Samita S. Andreansky, Bin He, G. Yancey Gillespie, Liliana Soroceanu, James Markert, Joany Chou, Bernard Roizman, and Richard J. Whitley

The application of genetically engineered herpes simplex viruses to the treatment of experimental brain tumors
PNAS 1996 93: 11313-11318. [Abstract] [PDF]  

Peggy Marconi, David Krisky, Thomas Oligino, Pietro L. Poliani, Ramesh Ramakrishnan, William F. Goins, David J. Fink, and Joseph C. Glorioso

Replication-defective herpes simplex virus vectors for gene transfer in vivo
PNAS 1996 93: 11319-11320. [Abstract] [PDF]  

Edward S. Mocarski, George W. Kemble, John M. Lyle, and Richard F. Greaves

A deletion mutant in the human cytomegalovirus gene encoding IE1_491aa is replication defective due to a failure in autoregulation
PNAS 1996 93: 11321-11326. [Abstract] [PDF]  

Thomas R. Jones, Emmanuel J. H. J. Wiertz, Lei Sun, Kenneth N. Fish, Jay A. Nelson, and Hidde L. Ploegh

Human cytomegalovirus US3 impairs transport and maturation of major histocompatibility complex class I heavy chains
PNAS 1996 93: 11327-11333. [Abstract] [PDF]  

Erle S. Robertson, Tadamasa Ooka, and Elliott D. Kieff

Epstein-Barr virus vectors for gene delivery to B lymphocytes
PNAS 1996 93: 11334-11340. [Abstract] [PDF]  

Bernard Moss

Genetically engineered poxviruses for recombinant gene expression, vaccination, and safety
PNAS 1996 93: 11341-11348. [Abstract] [PDF]  

Enzo Paoletti

Applications of pox virus vectors to vaccination: An update
PNAS 1996 93: 11349-11353. [Abstract] [PDF]  

Peter Palese, Hongyong Zheng, Othmar G. Engelhardt, Stephan Pleschka, and Adolfo García-Sastre

Negative-strand RNA viruses: Genetic engineering and applications
PNAS 1996 93: 11354-11358. [Abstract] [PDF]  

Matthias J. Schnell, Linda Buonocore, Evelyne Kretzschmar, Erik Johnson, and John K. Rose

Foreign glycoproteins expressed from recombinant vesicular stomatitis viruses are incorporated efficiently into virus particles
PNAS 1996 93: 11359-11365. [Abstract] [PDF]  

Teshome Mebatsion and Karl-Klaus Conzelmann

Specific infection of CD4⁺ target cells by recombinant rabies virus pseudotypes carrying the HIV-1 envelope spike protein
PNAS 1996 93: 11366-11370. [Abstract] [PDF]  

Ilya Frolov, Thomas A. Hoffman, Béla M. Prágai, Sergey A. Dryga, Henry V. Huang, Sondra Schlesinger, and Charles M. Rice

Alphavirus-based expression vectors: Strategies and applications
PNAS 1996 93: 11371-11377. [Abstract] [PDF]  

Vincent R. Racaniello

Early events in poliovirus infection: Virus-receptor interactions
PNAS 1996 93: 11378-11381. [Abstract] [PDF]  

Luigi Naldini, Ulrike Blömer, Fred H. Gage, Didier Trono, and Inder M. Verma

Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector
PNAS 1996 93: 11382-11388. [Abstract] [PDF]  

S. Monroe Duboise, Jie Guo, Ronald C. Desrosiers, and Jae U. Jung

Use of virion DNA as a cloning vector for the construction of mutant and recombinant herpesviruses
PNAS 1996 93: 11389-11394. [Abstract] [PDF]  

Eric Poeschla, Pierre Corbeau, and Flossie Wong-Staal

Development of HIV vectors for anti-HIV gene therapy
PNAS 1996 93: 11395-11399. [Abstract] [PDF]  

Daniel S. Ory, Beverly A. Neugeboren, and Richard C. Mulligan

A stable human-derived packaging cell line for production of high titer retrovirus/vesicular stomatitis virus G pseudotypes
PNAS 1996 93: 11400-11406. [Abstract] [PDF]  

A. Dusty Miller

Cell-surface receptors for retroviruses and implications for gene transfer
PNAS 1996 93: 11407-11413. [Abstract] [PDF]  

William L. McClements, Marcy E. Armstrong, Robert D. Keys, and Margaret A. Liu

Immunization with DNA vaccines encoding glycoprotein D or glycoprotein B, alone or in combination, induces protective immunity in animal models of herpes simplex virus-2 disease
PNAS 1996 93: 11414-11420. [Abstract] [PDF]  

Victor J. Dzau, Michael J. Mann, Ryuichi Morishita, and Yasufumi Kaneda

Fusigenic viral liposome for gene therapy in cardiovascular diseases
PNAS 1996 93: 11421-11425. [Abstract] [PDF]  

COMMENTARIES

J. Andrew McCammon

A speed limit for protein folding
PNAS 1996 93: 11426-11427. [Abstract] [PDF]  

REVIEWS

M. J. Corey and E. Corey

On the failure of de novo-designed peptides as biocatalysts
PNAS 1996 93: 11428-11434. [Abstract] [PDF]  

PHYSICAL SCIENCES
Chemistry

Vladik Avetisov and Vitalii Goldanskii INAUGURAL ARTICLE: Mirror symmetry breaking at the molecular level PNAS 1996 93: 11435-11442. [Abstract] [PDF]

Alexander Moscho, Owe Orwar, Daniel T. Chiu, Biren P. Modi, and Richard N. Zare

Rapid preparation of giant unilamellar vesicles
PNAS 1996 93: 11443-11447. [Abstract] [PDF]  

SOCIAL SCIENCES
Psychology

Steven Grant, Edythe D. London, David B. Newlin, Victor L. Villemagne, Xiang Liu, Carlo Contoreggi, Robert L. Phillips, Alane S. Kimes, and Arthur Margolin

Activation of memory circuits during cue-elicited cocaine craving
PNAS 1996 93: 12040-12045. [Abstract] [PDF]  

Florin Cutzu and Shimon Edelman

Faithful representation of similarities among three-dimensional shapes in human vision
PNAS 1996 93: 12046-12050. [Abstract] [PDF]  

BIOLOGICAL SCIENCES
Applied Biological Sciences

Jeffrey M. Hoeg, Silvia Santamarina-Fojo, Annie M. Bérard, J. Fredrick Cornhill, Edward E. Herderick, Sanford H. Feldman, Christian C. Haudenschild, Boris L. Vaisman, Robert F. Hoyt Jr., Stephen J. Demosky Jr., Richard D. Kauffman, Christina M. Hazel, Santica M. Marcovina, and H. Bryan Brewer Jr.

Overexpression of lecithin:cholesterol acyltransferase in transgenic rabbits prevents diet-induced atherosclerosis
PNAS 1996 93: 11448-11453. [Abstract] [PDF]  

Carl J. Wheeler, Philip L. Felgner, Yali J. Tsai, John Marshall, Loretta Sukhu, Soeun G. Doh, Jukka Hartikka, Jennifer Nietupski, Marston Manthorpe, Margaret Nichols, Michael Plewe, Xiaowu Liang, Jon Norman, Alan Smith, and Seng H. Cheng

A novel cationic lipid greatly enhances plasmid DNA delivery and expression in mouse lung
PNAS 1996 93: 11454-11459. [Abstract] [PDF]  

Leticia Castillo, Louis Beaumier, Alfred M. Ajami, and Vernon R. Young

Whole body nitric oxide synthesis in healthy men determined from [¹⁵N]arginine-to-[¹⁵N]citrulline labeling
PNAS 1996 93: 11460-11465. [Abstract] [PDF]  

Biochemistry

Joohun Ha, Jung-Kee Lee, Kyung-Sup Kim, Lee A. Witters, and Ki-Han Kim

Cloning of human acetyl-CoA carboxylase- and its unique features
PNAS 1996 93: 11466-11470. [Abstract] [PDF]  

Benhur Lee, A. Gregory Matera, David C. Ward, and Joe Craft

Association of RNase mitochondrial RNA processing enzyme with ribonuclease P in higher ordered structures in the nucleolus: A possible coordinate role in ribosome biogenesis
PNAS 1996 93: 11471-11476. [Abstract] [PDF]  

Fiona McPhee, Andrew C. Good, Irwin D. Kuntz, and Charles S. Craik

Engineering human immunodeficiency virus 1 protease heterodimers as macromolecular inhibitors of viral maturation
PNAS 1996 93: 11477-11481. [Abstract] [PDF]  

Ramin Mollaaghababa, Florence F. Davidson, Chris Kaiser, and H. Gobind Khorana

Structure and function in rhodopsin: Expression of functional mammalian opsin in Saccharomyces cerevisiae
PNAS 1996 93: 11482-11486. [Abstract] [PDF]  

P. J. Reeves, R. L. Thurmond, and H. G. Khorana

Structure and function in rhodopsin: High level expression of a synthetic bovine opsin gene and its mutants in stable mammalian cell lines
PNAS 1996 93: 11487-11492. [Abstract] [PDF]  

Olivier Zelphati and Francis C. Szoka Jr.

Mechanism of oligonucleotide release from cationic liposomes
PNAS 1996 93: 11493-11498. [Abstract] [PDF]  

Aharon Gal, Snait Tamir, Steven R. Tannenbaum, and Gerald N. Wogan

Nitric oxide production in SJL mice bearing the RcsX lymphoma: A model for in vivo toxicological evaluation of NO^·
PNAS 1996 93: 11499-11503. [Abstract] [PDF]  

Richard W. Kriwacki, Ludger Hengst, Linda Tennant, Steven I. Reed, and Peter E. Wright

Structural studies of p21^{Waf1/Cip1/Sdi1} in the free and Cdk2-bound state: Conformational disorder mediates binding diversity
PNAS 1996 93: 11504-11509. [Abstract] [PDF]  

Rafael E. Herrera, Feng Chen, and Robert A. Weinberg

Increased histone H1 phosphorylation and relaxed chromatin structure in Rb-deficient fibroblasts
PNAS 1996 93: 11510-11515. [Abstract] [PDF]  

A. J. van Wijnen, M. F. van Gurp, M. C. de Ridder, C. Tufarelli, T. J. Last, M. Birnbaum, P. S. Vaughan, A. Giordano, W. Krek, E. J. Neufeld, J. L. Stein, and G. S. Stein

CDP/cut is the DNA-binding subunit of histone gene transcription factor HiNF-D: A mechanism for gene regulation at the G₁/S phase cell cycle transition point independent of transcription factor E2F
PNAS 1996 93: 11516-11521. [Abstract] [PDF]  

Alessio Peracchi, Leonid Beigelman, Nassim Usman, and Daniel Herschlag

Rescue of abasic hammerhead ribozymes by exogenous addition of specific bases
PNAS 1996 93: 11522-11527. [Abstract] [PDF]  

Donald P. Shepley and John W. Little

Mutant LexA proteins with specific defects in autodigestion
PNAS 1996 93: 11528-11533. [Abstract] [PDF]  

Shu-wei Yang, Alex B. Burgin Jr., Beth N. Huizenga, Carol A. Robertson, Kevin C. Yao, and Howard A. Nash

A eukaryotic enzyme that can disjoin dead-end covalent complexes between DNA and type I topoisomerases
PNAS 1996 93: 11534-11539. [Abstract] [PDF]  

Bettina Hanstein, Richard Eckner, James DiRenzo, Shlomit Halachmi, Hong Liu, Brian Searcy, Riki Kurokawa, and Myles Brown

p300 is a component of an estrogen receptor coactivator complex
PNAS 1996 93: 11540-11545. [Abstract] [PDF]  

Andrew G. Hughson and Gerald L. Hazelbauer

Detecting the conformational change of transmembrane signaling in a bacterial chemoreceptor by measuring effects on disulfide cross-linking in vivo
PNAS 1996 93: 11546-11551. [Abstract] [PDF]  

Jiusheng Wu, Donald E. Awrey, Aled M. Edwards, Jacques Archambault, and James D. Friesen

In vitro characterization of mutant yeast RNA polymerase II with reduced binding for elongation factor TFIIS
PNAS 1996 93: 11552-11557. [Abstract] [PDF]  

David Brown and Larry Gold

RNA replication by Q replicase: A working model
PNAS 1996 93: 11558-11562. [Abstract] [PDF]  

Thomas Strahl, Hendrik Gille, and Peter E. Shaw

Selective response of ternary complex factor Sap1a to different mitogen-activated protein kinase subgroups
PNAS 1996 93: 11563-11568. [Abstract] [PDF]  

Nader Shakibai, Vijay Kumar, and Shlomo Eisenberg

The Ku-like protein from Saccharomyces cerevisiae is required in vitro for the assembly of a stable multiprotein complex at a eukaryotic origin of replication
PNAS 1996 93: 11569-11574. [Abstract] [PDF]  

Hiroshi Okamoto, Christian T. Sheline, Jeffry L. Corden, Katherine A. Jones, and B. Matija Peterlin

Trans-activation by human immunodeficiency virus Tat protein requires the C-terminal domain of RNA polymerase II
PNAS 1996 93: 11575-11579. [Abstract] [PDF]  

Gong-jie Cao, Joe Pogliano, and Nilima Sarkar

Identification of the coding region for a second poly(A) polymerase in Escherichia coli
PNAS 1996 93: 11580-11585. [Abstract] [PDF]  

David B. Bregman, Ruth Halaban, Alain J. van Gool, Karla A. Henning, Errol C. Friedberg, and Stephen L. Warren

UV-induced ubiquitination of RNA polymerase II: A novel modification deficient in Cockayne syndrome cells
PNAS 1996 93: 11586-11590. [Abstract] [PDF]  

Roney Graf and H. K. Schachman

Random circular permutation of genes and expressed polypeptide chains: Application of the method to the catalytic chains of aspartate transcarbamoylase
PNAS 1996 93: 11591-11596. [Abstract] [PDF]  

Junjie Chen, Steven Chen, Partha Saha, and Anindya Dutta

p21^Cip1/Waf1 disrupts the recruitment of human Fen1 by proliferating-cell nuclear antigen into the DNA replication complex
PNAS 1996 93: 11597-11602. [Abstract] [PDF]  

Benfang Ruan, Justin Shey, Nicolas Gerst, William K. Wilson, and George J. Schroepfer Jr.

Silver ion high pressure liquid chromatography provides unprecedented separation of sterols: Application to the enzymatic formation of cholesta-5,8-dien-3-ol
PNAS 1996 93: 11603-11608. [Abstract] [PDF]  

Biophysics

Emanuele Paci and Massimo Marchi

Intrinsic compressibility and volume compression in solvated proteins by molecular dynamics simulation at high pressure
PNAS 1996 93: 11609-11614. [Abstract] [PDF]  

Stephen J. Hagen, James Hofrichter, Attila Szabo, and William A. Eaton

Diffusion-limited contact formation in unfolded cytochrome c: Estimating the maximum rate of protein folding
PNAS 1996 93: 11615-11617. [Abstract] [PDF]  

Paul Kolodner, Evgeniy P. Lukashev, Yuan-chin Ching, and Denis L. Rousseau

Electric-field-induced Schiff-base deprotonation in D85N mutant bacteriorhodopsin
PNAS 1996 93: 11618-11621. [Abstract] [PDF]  

Samuel J. Landry, Abida Taher, Costa Georgopoulos, and Saskia M. van der Vies

Interplay of structure and disorder in cochaperonin mobile loops
PNAS 1996 93: 11622-11627. [Abstract] [PDF]  

Paul D. Thomas and Ken A. Dill

An iterative method for extracting energy-like quantities from protein structures
PNAS 1996 93: 11628-11633. [Abstract] [PDF]  

Jennifer R. Giorgione, Salvatore J. Turco, and Richard M. Epand

Transbilayer inhibition of protein kinase C by the lipophosphoglycan from Leishmania donovani
PNAS 1996 93: 11634-11639. [Abstract] [PDF]  

Beverly Z. Packard, Dmitri D. Toptygin, Akira Komoriya, and Ludwig Brand

Profluorescent protease substrates: Intramolecular dimers described by the exciton model
PNAS 1996 93: 11640-11645. [Abstract] [PDF]  

Cell Biology

Paul C. Park and U. De Boni

Transposition of DNase hypersensitive chromatin to the nuclear periphery coincides temporally with nerve growth factor-induced up-regulation of gene expression in PC12 cells
PNAS 1996 93: 11646-11651. [Abstract] [PDF]  

Paul Blount, Sergei I. Sukharev, Matthew J. Schroeder, Scott K. Nagle, and Ching Kung

Single residue substitutions that change the gating properties of a mechanosensitive channel in Escherichia coli
PNAS 1996 93: 11652-11657. [Abstract] [PDF]  

Ke-Jun Li and Henrik Garoff

Production of infectious recombinant Moloney murine leukemia virus particles in BHK cells using Semliki Forest virus-derived RNA expression vectors
PNAS 1996 93: 11658-11663. [Abstract] [PDF]  

Michael P. Yaffe, Dai Harata, Fulvia Verde, Mark Eddison, Takashi Toda, and Paul Nurse

Microtubules mediate mitochondrial distribution in fission yeast
PNAS 1996 93: 11664-11668. [Abstract] [PDF]  

Shijie Sheng, Juliana Carey, Elisabeth A. Seftor, Lauren Dias, Mary J. C. Hendrix, and Ruth Sager

Maspin acts at the cell membrane to inhibit invasion and motility of mammary and prostatic cancer cells
PNAS 1996 93: 11669-11674. [Abstract] [PDF]  

Maurizio Orlandini, Lucia Marconcini, Rebecca Ferruzzi, and Salvatore Oliviero

Identification of a c-fos-induced gene that is related to the platelet-derived growth factor/vascular endothelial growth factor family
PNAS 1996 93: 11675-11680. [Abstract] [PDF]  

Kai Xia, Nishit K. Mukhopadhyay, Roger C. Inhorn, Dwayne L. Barber, Paul E. Rose, Robert S. Lee, Radha P. Narsimhan, Alan D. D'Andrea, James D. Griffin, and Thomas M. Roberts

The cytokine-activated tyrosine kinase JAK2 activates Raf-1 in a p21^ras-dependent manner
PNAS 1996 93: 11681-11686. [Abstract] [PDF]  

Developmental Biology

Marco Milán, Sonsoles Campuzano, and Antonio García-Bellido

Cell cycling and patterned cell proliferation in the Drosophila wing during metamorphosis
PNAS 1996 93: 11687-11692. [Abstract] [PDF]  

Linda W. Jurata, Daryn A. Kenny, and Gordon N. Gill

Nuclear LIM interactor, a rhombotin and LIM homeodomain interacting protein, is expressed early in neuronal development
PNAS 1996 93: 11693-11698. [Abstract] [PDF]  

Katsuhiko Nishimori, Larry J. Young, Qiuxia Guo, Zuoxin Wang, Thomas R. Insel, and Martin M. Matzuk

Oxytocin is required for nursing but is not essential for parturition or reproductive behavior
PNAS 1996 93: 11699-11704. [Abstract] [PDF]  

Ecology

Friederike Wagner, Raimond Below, Pim De Klerk, David L. Dilcher, Hans Joosten, Wolfram M. Kürschner, and Henk Visscher

A natural experiment on plant acclimation: Lifetime stomatal frequency response of an individual tree to annual atmospheric CO₂ increase
PNAS 1996 93: 11705-11708. [Abstract] [PDF]  

Gretchen C. Daily and Paul R. Ehrlich

Nocturnality and species survival
PNAS 1996 93: 11709-11712. [Abstract] [PDF]  

Evolution

Ruud J. Poort, Henk Visscher, and David L. Dilcher

Zoidogamy in fossil gymnosperms: The centenary of a concept, with special reference to prepollen of late Paleozoic conifers
PNAS 1996 93: 11713-11717. [Abstract] [PDF]  

Tugrul Giray and Gene E. Robinson

Common endocrine and genetic mechanisms of behavioral development in male and worker honey bees and the evolution of division of labor
PNAS 1996 93: 11718-11722. [Abstract] [PDF]  

Hans Ellegren, Lars Gustafsson, and Ben C. Sheldon

Sex ratio adjustment in relation to paternal attractiveness in a wild bird population
PNAS 1996 93: 11723-11728. [Abstract] [PDF]  

Francisco J. Ayala, Eladio Barrio, and Jan Kwiatowski

Molecular clock or erratic evolution? A tale of two genes
PNAS 1996 93: 11729-11734. [Abstract] [PDF]  

Brian R. Morton, Brandon S. Gaut, and Michael T. Clegg

Evolution of alcohol dehydrogenase genes in the Palm and Grass families
PNAS 1996 93: 11735-11739. [Abstract] [PDF]  

Uta-Regina Böhle, Hartmut H. Hilger, and William F. Martin

Island colonization and evolution of the insular woody habit in Echium L. (Boraginaceae)
PNAS 1996 93: 11740-11745. [Abstract] [PDF]  

Genetics

Vladimir Kanazin, Laura Fredrick Marek, and Randy C. Shoemaker

Resistance gene analogs are conserved and clustered in soybean
PNAS 1996 93: 11746-11750. [Abstract] [PDF]  

Yong G. Yu, Glenn R. Buss, and M. A. Saghai Maroof

Isolation of a superfamily of candidate disease-resistance genes in soybean based on a conserved nucleotide-binding site
PNAS 1996 93: 11751-11756. [Abstract] [PDF]  

Jean-Pierre J. Issa, Paula M. Vertino, Corinne D. Boehm, Irene F. Newsham, and Stephen B. Baylin

Switch from monoallelic to biallelic human IGF2 promoter methylation during aging and carcinogenesis
PNAS 1996 93: 11757-11762. [Abstract] [PDF]  

Shichuan He, Andre R. Abad, Stanton B. Gelvin, and Sally A. Mackenzie

A cytoplasmic male sterility-associated mitochondrial protein causes pollen disruption in transgenic tobacco
PNAS 1996 93: 11763-11768. [Abstract] [PDF]  

Maria Dolores Ochando, Aurelio Reyes, and Francisco J. Ayala

Multiple paternity in two natural populations (orchard and vineyard) of Drosophila
PNAS 1996 93: 11769-11773. [Abstract] [PDF]  

Immunology

Scott J. Roberts, Adrian L. Smith, A. Brian West, Li Wen, R. Craig Findly, Michael J. Owen, and Adrian C. Hayday

T-cell ⁺ and ⁺ deficient mice display abnormal but distinct phenotypes toward a natural, widespread infection of the intestinal epithelium
PNAS 1996 93: 11774-11779. [Abstract] [PDF]  

Kathryn T. Hall, Laurence Boumsell, Joachim L. Schultze, Vassiliki A. Boussiotis, David M. Dorfman, Angelo A. Cardoso, Armand Bensussan, Lee M. Nadler, and Gordon J. Freeman

Human CD100, a novel leukocyte semaphorin that promotes B-cell aggregation and differentiation
PNAS 1996 93: 11780-11785. [Abstract] [PDF]  

Richard J. Mazzaccaro, Margaret Gedde, Eric R. Jensen, Hisse M. van Santen, Hidde L. Ploegh, Kenneth L. Rock, and Barry R. Bloom

Major histocompatibility class I presentation of soluble antigen facilitated by Mycobacterium tuberculosis infection
PNAS 1996 93: 11786-11791. [Abstract] [PDF]  

Michael Orihuela, David H. Margulies, and Wayne M. Yokoyama

The natural killer cell receptor Ly-49A recognizes a peptide-induced conformational determinant on its major histocompatibility complex class I ligand
PNAS 1996 93: 11792-11797. [Abstract] [PDF]  

Yuji Noguchi, Achim Jungbluth, Elizabeth C. Richards, and Lloyd J. Old

Effect of interleukin 12 on tumor induction by 3-methylcholanthrene
PNAS 1996 93: 11798-11801. [Abstract] [PDF]  

Medical Sciences

Yoshihisa Umekita, Richard A. Hiipakka, John M. Kokontis, and Shutsung Liao

Human prostate tumor growth in athymic mice: Inhibition by androgens and stimulation by finasteride
PNAS 1996 93: 11802-11807. [Abstract] [PDF]  

Theresa T. Lu, Linda G. Yan, and Joseph A. Madri

Integrin engagement mediates tyrosine dephosphorylation on platelet-endothelial cell adhesion molecule 1
PNAS 1996 93: 11808-11813. [Abstract] [PDF]  

J. W. Teague, A. Collins, and N. E. Morton

Studies on locus content mapping
PNAS 1996 93: 11814-11818. [Abstract] [PDF]  

Xue-Yan Liu, Sheila Timmons, Yao-Zhong Lin, and Jacek Hawiger

Identification of a functionally important sequence in the cytoplasmic tail of integrin ₃ by using cell-permeable peptide analogs
PNAS 1996 93: 11819-11824. [Abstract] [PDF]  

Aki Nagata, Mitsuhiro Ito, Nobuko Iwata, Junko Kuno, Hiroshi Takano, Osamu Minowa, Kazuo Chihara, Toshimitsu Matsui, and Tetsuo Noda

G protein-coupled cholecystokinin-B/gastrin receptors are responsible for physiological cell growth of the stomach mucosa in vivo
PNAS 1996 93: 11825-11830. [Abstract] [PDF]  

Chaoting Liu, Eileen Adamson, and Dan Mercola

Transcription factor EGR-1 suppresses the growth and transformation of human HT-1080 fibrosarcoma cells by induction of transforming growth factor 1
PNAS 1996 93: 11831-11836. [Abstract] [PDF]  

Stephan Stilgenbauer, Peter Liebisch, Michael R. James, Martin Schröder, Brigitte Schlegelberger, Konstanze Fischer, Martin Bentz, Peter Lichter, and Hartmut Döhner

Molecular cytogenetic delineation of a novel critical genomic region in chromosome bands 11q22.3-923.1 in lymphoproliferative disorders
PNAS 1996 93: 11837-11841. [Abstract] [PDF]  

Sanjai Sharma, Mark Cantwell, Thomas J. Kipps, and Theodore Friedmann

Efficient infection of a human T-cell line and of human primary peripheral blood leukocytes with a pseudotyped retrovirus vector
PNAS 1996 93: 11842-11847. [Abstract] [PDF]  

Thomas M. Johnson, Zu-Xi Yu, Victor J. Ferrans, Robert A. Lowenstein, and Toren Finkel

Reactive oxygen species are downstream mediators of p53-dependent apoptosis
PNAS 1996 93: 11848-11852. [Abstract] [PDF]  

L. A. MacMillan-Crow, John P. Crow, Jeffrey D. Kerby, Joseph S. Beckman, and John A. Thompson

Nitration and inactivation of manganese superoxide dismutase in chronic rejection of human renal allografts
PNAS 1996 93: 11853-11858. [Abstract] [PDF]  

Serguei Popov, Larisa Dubrovsky, May-Ann Lee, Sridhar Pennathur, Omar Haffar, Yousef Al-Abed, Peter Tonge, Peter Ulrich, Michael Rexach, Günter Blobel, Anthony Cerami, and Michael Bukrinsky

Critical role of reverse transcriptase in the inhibitory mechanism of CNI-H0294 on HIV-1 nuclear translocation
PNAS 1996 93: 11859-11864. [Abstract] [PDF]  

David J. Sullivan Jr., Ilya Y. Gluzman, David G. Russell, and Daniel E. Goldberg

On the molecular mechanism of chloroquine's antimalarial action
PNAS 1996 93: 11865-11870. [Abstract] [PDF]  

Cynthia E. Dunbar, Nancy E. Seidel, Sandra Doren, Stephanie Sellers, Amanda P. Cline, Mark E. Metzger, Brian A. Agricola, Robert E. Donahue, and David M. Bodine

Improved retroviral gene transfer into murine and rhesus peripheral blood or bone marrow repopulating cells primed in vivo with stem cell factor and granulocyte colony-stimulating factor
PNAS 1996 93: 11871-11876. [Abstract] [PDF]  

Alan D. Michelson, Marc R. Barnard, Herbert B. Hechtman, Hollace MacGregor, Raymond J. Connolly, Joseph Loscalzo, and C. Robert Valeri

In vivo tracking of platelets: Circulating degranulated platelets rapidly lose surface P-selectin but continue to circulate and function
PNAS 1996 93: 11877-11882. [Abstract] [PDF]  

Ren Sun, Su-Fang Lin, Lyn Gradoville, and George Miller

Polyadenylylated nuclear RNA encoded by Kaposi sarcoma- associated herpesvirus
PNAS 1996 93: 11883-11888. [Abstract] [PDF]  

Thomas F. McCutchan, Jessica C. Kissinger, Musa G. Touray, M. John Rogers, Jun Li, Margery Sullivan, Erika M. Braga, Antoniana U. Krettli, and Louis H. Miller

Comparison of circumsporozoite proteins from avian and mammalian malarias: Biological and phylogenetic implications
PNAS 1996 93: 11889-11894. [Abstract] [PDF]  

Kristina L. Rhoades, Christopher J. Hetherington, Janet D. Rowley, Scott W. Hiebert, Giuseppina Nucifora, Daniel G. Tenen, and Dong-Er Zhang

Synergistic up-regulation of the myeloid-specific promoter for the macrophage colony-stimulating factor receptor by AML1 and the t(8;21) fusion protein may contribute to leukemogenesis
PNAS 1996 93: 11895-11900. [Abstract] [PDF]  

Noam Shani and David Valle

A Saccharomyces cerevisiae homolog of the human adrenoleukodystrophy transporter is a heterodimer of two half ATP-binding cassette transporters
PNAS 1996 93: 11901-11906. [Abstract] [PDF]  

Microbiology

Mark A. Ragan, C. Louise Goggin, Richard J. Cawthorn, Lage Cerenius, Angela V. C. Jamieson, Susan M. Plourde, Thomas G. Rand, Kenneth Söderhäll, and Robin R. Gutell

A novel clade of protistan parasites near the animal-fungal divergence
PNAS 1996 93: 11907-11912. [Abstract] [PDF]  

Joseph W. St. Geme III, Jerome S. Pinkner, Graham P. Krasan, John Heuser, Esther Bullitt, Arnold L. Smith, and Scott J. Hultgren

Haemophilus influenzae pili are composite structures assembled via the HifB chaperone
PNAS 1996 93: 11913-11918. [Abstract] [PDF]  

Aimee E. Belanger, Gurdyal S. Besra, Michael E. Ford, Katarina Mikusova, John T. Belisle, Patrick J. Brennan, and Julia M. Inamine

The embAB genes of Mycobacterium avium encode an arabinosyl transferase involved in cell wall arabinan biosynthesis that is the target for the antimycobacterial drug ethambutol
PNAS 1996 93: 11919-11924. [Abstract] [PDF]  

Neurobiology

Erwin Frise, Jürgen A. Knoblich, Susan Younger-Shepherd, Lily Y. Jan, and Yuh Nung Jan INAUGURAL ARTICLE: The Drosophila Numb protein inhibits signaling of the Notch receptor during cell-cell interaction in sensory organ lineage PNAS 1996 93: 11925-11932. [Abstract] [PDF]

Hitoshi Okazawa, Ichiro Imafuku, Mari T. Minowa, Ichiro Kanazawa, Hiroshi Hamada, and M. Maral Mouradian

Regulation of striatal D_1A dopamine receptor gene transcription by Brn-4
PNAS 1996 93: 11933-11938. [Abstract] [PDF]  

Zoltan Nusser, Werner Sieghart, Dietmar Benke, Jean-Marc Fritschy, and Peter Somogyi

Differential synaptic localization of two major -aminobutyric acid type A receptor  subunits on hippocampal pyramidal cells
PNAS 1996 93: 11939-11944. [Abstract] [PDF]  

Harald Hirling and Richard H. Scheller

Phosphorylation of synaptic vesicle proteins: Modulation of the SNAP interaction with the core complex
PNAS 1996 93: 11945-11949. [Abstract] [PDF]  

Mengqing Xiang, Lin Gan, Lijuan Zhou, William H. Klein, and Jeremy Nathans

Targeted deletion of the mouse POU domain gene Brn-3a causes a selective loss of neurons in the brainstem and trigeminal ganglion, uncoordinated limb movement, and impaired suckling
PNAS 1996 93: 11950-11955. [Abstract] [PDF]  

Emilio Salinas and L. F. Abbott

A model of multiplicative neural responses in parietal cortex
PNAS 1996 93: 11956-11961. [Abstract] [PDF]  

Daniel C. Javitt, Mitchell Steinschneider, Charles E. Schroeder, and Joseph C. Arezzo

Role of cortical N-methyl-D-aspartate receptors in auditory sensory memory and mismatch negativity generation: Implications for schizophrenia
PNAS 1996 93: 11962-11967. [Abstract] [PDF]  

Sylvie Zini, Marie-Claude Fournie-Zaluski, Eric Chauvel, Bernard P. Roques, Pierre Corvol, and Catherine Llorens-Cortes

Identification of metabolic pathways of brain angiotensin II and III using specific aminopeptidase inhibitors: Predominant role of angiotensin III in the control of vasopressin release
PNAS 1996 93: 11968-11973. [Abstract] [PDF]  

Sung Ok Yoon, Carlos Lois, Mauricio Alvirez, Arturo Alvarez-Buylla, Erik Falck-Pedersen, and Moses V. Chao

Adenovirus-mediated gene delivery into neuronal precursors of the adult mouse brain
PNAS 1996 93: 11974-11979. [Abstract] [PDF]  

A. Courtney DeVries, M. Brigid DeVries, Susan E. Taymans, and C. Sue Carter

The effects of stress on social preferences are sexually dimorphic in prairie voles
PNAS 1996 93: 11980-11984. [Abstract] [PDF]  

M. Rapp, Y. Yarom, and I. Segev

Modeling back propagating action potential in weakly excitable dendrites of neocortical pyramidal cells
PNAS 1996 93: 11985-11990. [Abstract] [PDF]  

Pharmacology

Haris Jamil, David A. Gordon, David C. Eustice, Cindy M. Brooks, John K. Dickson Jr., Ying Chen, Beverly Ricci, Ching-Hsuen Chu, Thomas W. Harrity, Carl P. Ciosek Jr., Scott A. Biller, Richard E. Gregg, and John R. Wetterau

An inhibitor of the microsomal triglyceride transfer protein inhibits apoB secretion from HepG2 cells
PNAS 1996 93: 11991-11995. [Abstract] [PDF]  

Physiology

Pedro Cuevas, Margarita García-Calvo, Fernando Carceller, Diana Reimers, Mercedes Zazo, Begoña Cuevas, Isabel Muñoz-Willery, Victoria Martínez-Coso, Santiago Lamas, and Guillermo Giménez-Gallego

Correction of hypertension by normalization of endothelial levels of fibroblast growth factor and nitric oxide synthase in spontaneously hypertensive rats
PNAS 1996 93: 11996-12001. [Abstract] [PDF]  

R. Gregg Richards, Richard P. DiAugustine, Peter Petrusz, George C. Clark, and Joseph Sebastian

Estradiol stimulates tyrosine phosphorylation of the insulin-like growth factor-1 receptor and insulin receptor substrate-1 in the uterus
PNAS 1996 93: 12002-12007. [Abstract] [PDF]  

Alan J. Burns, Alan E. J. Lomax, Shigeko Torihashi, Kenton M. Sanders, and Sean M. Ward

Interstitial cells of Cajal mediate inhibitory neurotransmission in the stomach
PNAS 1996 93: 12008-12013. [Abstract] [PDF]  

S.-L. Shyng, Q. Sha, T. Ferrigni, A. N. Lopatin, and C. G. Nichols

Depletion of intracellular polyamines relieves inward rectification of potassium channels
PNAS 1996 93: 12014-12019. [Abstract] [PDF]  

Yu Wang, Richard Roman, Steven D. Lidofsky, and J. Gregory Fitz

Autocrine signaling through ATP release represents a novel mechanism for cell volume regulation
PNAS 1996 93: 12020-12025. [Abstract] [PDF]  

Plant Biology

Steffen Reinbothe, Christiane Reinbothe, Dieter Neumann, and Klaus Apel

A plastid enzyme arrested in the step of precursor translocation in vivo
PNAS 1996 93: 12026-12030. [Abstract] [PDF]  

Mats Eriksson, Jan Karlsson, Zakir Ramazanov, Per Gardeström, and Göran Samuelsson

Discovery of an algal mitochondrial carbonic anhydrase: Molecular cloning and characterization of a low-CO₂-induced polypeptide in Chlamydomonas reinhardtii
PNAS 1996 93: 12031-12034. [Abstract] [PDF]  

Population Biology

Antti Sajantila, Abdel-Halim Salem, Peter Savolainen, Karin Bauer, Christian Gierig, and Svante Pääbo

Paternal and maternal DNA lineages reveal a bottleneck in the founding of the Finnish population
PNAS 1996 93: 12035-12039. [Abstract] [PDF]  

CORRECTIONS

Correction for vol. 92, p. 200 [Abstract]  

Correction for vol. 92, p. 11451 [Abstract]  

Correction for vol. 91, p. 1475 [Abstract]  

Correction for vol. 93, p. 6158 [Abstract]  

Correction for vol. 93, p. 6970 [Abstract]