COLLOQUIUM:
Papers from an NAS Colloquium on Protecting Our Food Supply: The Value of Plant Genome Initiatives

Ronald L. Phillips and Michael Freeling

Plant genomics and our food supply: An introduction
PNAS 1998 95: 1969-1970. [Full Text] [PDF]  

Michael D. Gale and Katrien M. Devos

Comparative genetics in the grasses
PNAS 1998 95: 1971-1974. [Abstract] [Full Text] [PDF]  

Jeffrey L. Bennetzen, Phillip SanMiguel, Mingsheng Chen, Alexander Tikhonov, Michael Francki, and Zoya Avramova

Grass genomes
PNAS 1998 95: 1975-1978. [Abstract] [Full Text] [PDF]  

Junko Kyozuka, Saeko Konishi, Keisuke Nemoto, Takeshi Izawa, and Ko Shimamoto

Down-regulation of RFL, the FLO/LFY homolog of rice, accompanied with panicle branch initiation
PNAS 1998 95: 1979-1982. [Abstract] [Full Text] [PDF]  

Susan McCouch

Toward a plant genomics initiative: Thoughts on the value of cross-species and cross-genera comparisons in the grasses
PNAS 1998 95: 1983-1985. [Abstract] [Full Text] [PDF]  

Steven P. Briggs

Plant genomics: More than food for thought
PNAS 1998 95: 1986-1988. [Abstract] [Full Text] [PDF]  

Robert W. Herdt

Assisting developing countries toward food self-reliance
PNAS 1998 95: 1989-1992. [Abstract] [Full Text] [PDF]  

R. James Cook

Toward a successful multinational crop plant genome initiative
PNAS 1998 95: 1993-1995. [Abstract] [Full Text] [PDF]  

M. D. McMullen, P. F. Byrne, M. E. Snook, B. R. Wiseman, E. A. Lee, N. W. Widstrom, and E. H. Coe

Quantitative trait loci and metabolic pathways
PNAS 1998 95: 1996-2000. [Abstract] [Full Text] [PDF]  

Michael Lee

Genome projects and gene pools: New germplasm for plant breeding?
PNAS 1998 95: 2001-2004. [Abstract] [Full Text] [PDF]  

Elizabeth A. Kellogg

Relationships of cereal crops and other grasses
PNAS 1998 95: 2005-2010. [Abstract] [Full Text] [PDF]  

Michael D. Bennett

Plant genome values: How much do we know?
PNAS 1998 95: 2011-2016. [Abstract] [Full Text] [PDF]  

Joachim Messing and Victor Llaca

Importance of anchor genomes for any plant genome project
PNAS 1998 95: 2017-2020. [Abstract] [Full Text] [PDF]  

Robert A. Martienssen

Functional genomics: Probing plant gene function and expression with transposons
PNAS 1998 95: 2021-2026. [Abstract] [Full Text] [PDF]  

Takuji Sasaki

The rice genome project in Japan
PNAS 1998 95: 2027-2028. [Abstract] [Full Text] [PDF]  

E. H. Coe

Potentials of the National Corn Genome Initiative
PNAS 1998 95: 2029-2032. [Abstract] [Full Text] [PDF]  

COMMENTARIES

Ernest Beutler

Targeted disruption of the HFE gene
PNAS 1998 95: 2033-2034. [Full Text] [PDF]  

Frances H. Arnold

Enzyme engineering reaches the boiling point
PNAS 1998 95: 2035-2036. [Full Text] [PDF]  

Larry Simpson

A base called J
PNAS 1998 95: 2037-2038. [Full Text] [PDF]  

PHYSICAL SCIENCES
Physics

Martin B. Tarlie and R. Dean Astumian

Optimal modulation of a Brownian ratchet and enhanced sensitivity to a weak external force
PNAS 1998 95: 2039-2043. [Abstract] [Full Text] [PDF]  

SOCIAL SCIENCES

BIOLOGICAL SCIENCES
Applied Biological Sciences

Kerry O'Donnell, H. Corby Kistler, Elizabeth Cigelnik, and Randy C. Ploetz

Multiple evolutionary origins of the fungus causing Panama disease of banana: Concordant evidence from nuclear and mitochondrial gene genealogies
PNAS 1998 95: 2044-2049. [Abstract] [Full Text] [PDF]  

Biochemistry

Inez Rogatsky, Susan K. Logan, and Michael J. Garabedian

Antagonism of glucocorticoid receptor transcriptional activation by the c-Jun N-terminal kinase
PNAS 1998 95: 2050-2055. [Abstract] [Full Text] [PDF]  

Bertus Van den Burg, Gert Vriend, Oene R. Veltman, Gerard Venema, and Vincent G. H. Eijsink

Engineering an enzyme to resist boiling
PNAS 1998 95: 2056-2060. [Abstract] [Full Text] [PDF]  

Gerd A. Blobel, Toshihiro Nakajima, Richard Eckner, Marc Montminy, and Stuart H. Orkin

CREB-binding protein cooperates with transcription factor GATA-1 and is required for erythroid differentiation
PNAS 1998 95: 2061-2066. [Abstract] [Full Text] [PDF]  

Eleonora Candi, Edit Tarcsa, John J. Digiovanna, John G. Compton, Peter M. Elias, Lyuben N. Marekov, and Peter M. Steinert

A highly conserved lysine residue on the head domain of type II keratins is essential for the attachment of keratin intermediate filaments to the cornified cell envelope through isopeptide crosslinking by transglutaminases
PNAS 1998 95: 2067-2072. [Abstract] [Full Text] [PDF]  

Liam Good and Peter E. Nielsen

Inhibition of translation and bacterial growth by peptide nucleic acid targeted to ribosomal RNA
PNAS 1998 95: 2073-2076. [Abstract] [Full Text] [PDF]  

Yong Rao and S. Lawrence Zipursky

Domain requirements for the Dock adapter protein in growth- cone signaling
PNAS 1998 95: 2077-2082. [Abstract] [Full Text] [PDF]  

Qinghua Feng, Gerald Schumann, and Jef D. Boeke

Retrotransposon R1Bm endonuclease cleaves the target sequence
PNAS 1998 95: 2083-2088. [Abstract] [Full Text] [PDF]  

Dorothy J. Fiete, Mary C. Beranek, and Jacques U. Baenziger

A cysteine-rich domain of the "mannose" receptor mediates GalNAc-4-SO₄ binding
PNAS 1998 95: 2089-2093. [Abstract] [Full Text] [PDF]  

Alexander Varshavsky

Codominant interference, antieffectors, and multitarget drugs
PNAS 1998 95: 2094-2099. [Abstract] [Full Text] [PDF]  

B. Markus Lange, Mark R. Wildung, David McCaskill, and Rodney Croteau

A family of transketolases that directs isoprenoid biosynthesis via a mevalonate-independent pathway
PNAS 1998 95: 2100-2104. [Abstract] [Full Text] [PDF]  

Luisa Maria Lois, Narciso Campos, Surya Rosa Putra, Knut Danielsen, Michel Rohmer, and Albert Boronat

Cloning and characterization of a gene from Escherichia coli encoding a transketolase-like enzyme that catalyzes the synthesis of D-1-deoxyxylulose 5-phosphate, a common precursor for isoprenoid, thiamin, and pyridoxol biosynthesis
PNAS 1998 95: 2105-2110. [Abstract] [Full Text] [PDF]  

Eric A. Lee, Stacey L. Weiss, Mandy Lam, Rosa Torres, and Jared Diamond

A method for assaying intestinal brush-border sucrase in an intact intestinal preparation
PNAS 1998 95: 2111-2116. [Abstract] [Full Text] [PDF]  

Stacey L. Weiss, Eric A. Lee, and Jared Diamond

Evolutionary matches of enzyme and transporter capacities to dietary substrate loads in the intestinal brush border
PNAS 1998 95: 2117-2121. [Abstract] [Full Text] [PDF]  

Piia Aarnisalo, Jorma J. Palvimo, and Olli A. Jänne

CREB-binding protein in androgen receptor-mediated signaling
PNAS 1998 95: 2122-2127. [Abstract] [Full Text] [PDF]  

Elisabeth G. van Grunsven, Emanuel van Berkel, Lodewijk Ijlst, Peter Vreken, Johannis B. C. de Klerk, Jerzy Adamski, Hugh Lemonde, Peter T. Clayton, Dean A. Cuebas, and Ronald J. A. Wanders

Peroxisomal D-hydroxyacyl-CoA dehydrogenase deficiency: Resolution of the enzyme defect and its molecular basis in bifunctional protein deficiency
PNAS 1998 95: 2128-2133. [Abstract] [Full Text] [PDF]  

Judibelle Roman and Sarah A. Woodson

Integration of the Tetrahymena group I intron into bacterial rRNA by reverse splicing in vivo
PNAS 1998 95: 2134-2139. [Abstract] [Full Text] [PDF]  

Jochen Pavel, Cordula Harter, and Felix T. Wieland

Reversible dissociation of coatomer: Functional characterization of a /-coat protein subcomplex
PNAS 1998 95: 2140-2145. [Abstract] [Full Text] [PDF]  

Hua Xiao, Yong Tao, Jack Greenblatt, and Robert G. Roeder

A cofactor, TIP30, specifically enhances HIV-1 Tatactivated transcription
PNAS 1998 95: 2146-2151. [Abstract] [Full Text] [PDF]  

Lance J. Ferrin and R. Daniel Camerini-Otero

Sequence-specific ligation of DNA using RecA protein
PNAS 1998 95: 2152-2157. [Abstract] [Full Text] [PDF]  

Narendra K. Vaish, Paul A. Heaton, Olga Fedorova, and Fritz Eckstein

In vitro selection of a purine nucleotide-specific hammerheadlike ribozyme
PNAS 1998 95: 2158-2162. [Abstract] [Full Text] [PDF]  

Jeremy M. Stark, David P. Bazett-Jones, Manfred Herfort, and Mark B. Roth

SR proteins are sufficient for exon bridging across an intron
PNAS 1998 95: 2163-2168. [Abstract] [Full Text] [PDF]  

Alirio J. Melendez, David J. Gillooly, Margaret M. Harnett, and Janet M. Allen

Aggregation of the human high affinity immunoglobulin G receptor (FcRI) activates both tyrosine kinase and G protein-coupled phosphoinositide 3-kinase isoforms
PNAS 1998 95: 2169-2174. [Abstract] [Full Text] [PDF]  

Xiaoping Liu, Mark J. S. Miller, Mahesh S. Joshi, Douglas D. Thomas, and Jack R. Lancaster Jr.

Accelerated reaction of nitric oxide with O₂ within the hydrophobic interior of biological membranes
PNAS 1998 95: 2175-2179. [Abstract] [Full Text] [PDF]  

Heidi Walker, James A. Ferretti, and Thressa C. Stadtman

Isotope exchange studies on the Escherichia coli selenophosphate synthetase mechanism
PNAS 1998 95: 2180-2185. [Abstract] [Full Text] [PDF]  

Clifford R. Robinson and Stephen G. Sligar

Changes in solvation during DNA binding and cleavage are critical to altered specificity of the EcoRI endonuclease
PNAS 1998 95: 2186-2191. [Abstract] [Full Text] [PDF]  

Sohail Malik, Mohamed Guermah, and Robert G. Roeder

A dynamic model for PC4 coactivator function in RNA polymerase II transcription
PNAS 1998 95: 2192-2197. [Abstract] [Full Text] [PDF]  

Wing Ming Keung and Bert L. Vallee

Daidzin and its antidipsotropic analogs inhibit serotonin and dopamine metabolism in isolated mitochondria
PNAS 1998 95: 2198-2203. [Abstract] [Full Text] [PDF]  

Anthony J. A. Ouellette, Lorraine B. Anderson, and Bridgette A. Barry

Amine binding and oxidation at the catalytic site for photosynthetic water oxidation
PNAS 1998 95: 2204-2209. [Abstract] [Full Text] [PDF]  

Sylvie Vincent, Madeleine Brouns, Matthew J. Hart, and Jeffrey Settleman

Evidence for distinct mechanisms of transition state stabilization of GTPases by fluoride
PNAS 1998 95: 2210-2215. [Abstract] [Full Text] [PDF]  

Sheila M. Colby, John Crock, Barbara Dowdle-Rizzo, Peggy G. Lemaux, and Rodney Croteau

Germacrene C synthase from Lycopersicon esculentum cv. VFNT Cherry tomato: cDNA isolation, characterization, and bacterial expression of the multiple product sesquiterpene cyclase
PNAS 1998 95: 2216-2221. [Abstract] [Full Text] [PDF]  

Giulio Innamorati, Hamid M. Sadeghi, Nathaniel T. Tran, and Mariel Birnbaumer

A serine cluster prevents recycling of the V2 vasopressin receptor
PNAS 1998 95: 2222-2226. [Abstract] [Full Text] [PDF]  

Michael Janda and Paul Ahlquist

Brome mosaic virus RNA replication protein 1a dramatically increases in vivo stability but not translation of viral genomic RNA3
PNAS 1998 95: 2227-2232. [Abstract] [Full Text] [PDF]  

Nir Carmi, Shameelah R. Balkhi, and Ronald R. Breaker

Cleaving DNA with DNA
PNAS 1998 95: 2233-2237. [Abstract] [Full Text] [PDF]  

Christopher B. Yohn, Amybeth Cohen, Avihai Danon, and Stephen P. Mayfield

A poly(A) binding protein functions in the chloroplast as a message-specific translation factor
PNAS 1998 95: 2238-2243. [Abstract] [Full Text] [PDF]  

Richard S. Murante, Leigh A. Henricksen, and Robert A. Bambara

Junction ribonuclease: An activity in Okazaki fragment processing
PNAS 1998 95: 2244-2249. [Abstract] [Full Text] [PDF]  

Kai Hell, Johannes M. Herrmann, Elke Pratje, Walter Neupert, and Rosemary A. Stuart

Oxa1p, an essential component of the N-tail protein export machinery in mitochondria
PNAS 1998 95: 2250-2255. [Abstract] [Full Text] [PDF]  

Biophysics

Peter C. Simpson, David Roach, Adam T. Woolley, Todd Thorsen, Rick Johnston, George F. Sensabaugh, and Richard A. Mathies

High-throughput genetic analysis using microfabricated 96-sample capillary array electrophoresis microplates
PNAS 1998 95: 2256-2261. [Abstract] [Full Text] [PDF]  

T. Szyperski, C. Fernández, C. Mumenthaler, and K. Wüthrich

Structure comparison of human glioma pathogenesis-related protein GliPR and the plant pathogenesis-related protein P14a indicates a functional link between the human immune system and a plant defense system
PNAS 1998 95: 2262-2266. [Abstract] [Full Text] [PDF]  

D. I. Svergun, S. Richard, M. H. J. Koch, Z. Sayers, S. Kuprin, and G. Zaccai

Protein hydration in solution: Experimental observation by x-ray and neutron scattering
PNAS 1998 95: 2267-2272. [Abstract] [Full Text] [PDF]  

Haruo Sugi, Hiroyuki Iwamoto, Tsuyoshi Akimoto, and Hiroko Ushitani

Evidence for the load-dependent mechanical efficiency of individual myosin heads in skeletal muscle fibers activated by laser flash photolysis of caged calcium in the presence of a limited amount of ATP
PNAS 1998 95: 2273-2278. [Abstract] [Full Text] [PDF]  

Cell Biology

Lelio Orci, Alain Perrelet, and James E. Rothman

Vesicles on strings: Morphological evidence for processive transport within the Golgi stack
PNAS 1998 95: 2279-2283. [Abstract] [Full Text] [PDF]  

Mikhail V. Chernov, Chilakamarti V. Ramana, Victor V. Adler, and George R. Stark

Stabilization and activation of p53 are regulated independently by different phosphorylation events
PNAS 1998 95: 2284-2289. [Abstract] [Full Text] [PDF]  

Shiyu Song, Gene A. Gulliver, and Paul F. Lambert

Human papillomavirus type 16 E6 and E7 oncogenes abrogate radiation-induced DNA damage responses in vivo through p53-dependent and p53-independent pathways
PNAS 1998 95: 2290-2295. [Abstract] [Full Text] [PDF]  

Rebecca George, Travis Beddoe, Karina Landl, and Trevor Lithgow

The yeast nascent polypeptide-associated complex initiates protein targeting to mitochondria in vivo
PNAS 1998 95: 2296-2301. [Abstract] [Full Text] [PDF]  

Toru Ouchi, Alvaro N. A. Monteiro, Avery August, Stuart A. Aaronson, and Hidesaburo Hanafusa

BRCA1 regulates p53-dependent gene expression
PNAS 1998 95: 2302-2306. [Abstract] [Full Text] [PDF]  

Cornelia S. Seitz, Qun Lin, Helen Deng, and Paul A. Khavari

Alterations in NF-B function in transgenic epithelial tissue demonstrate a growth inhibitory role for NF-B
PNAS 1998 95: 2307-2312. [Abstract] [Full Text] [PDF]  

Peter Crino, Kamran Khodakhah, Kevin Becker, Stephen Ginsberg, Scott Hemby, and James Eberwine

Presence and phosphorylation of transcription factors in developing dendrites
PNAS 1998 95: 2313-2318. [Abstract] [Full Text] [PDF]  

K. Kaarniranta, M. Elo, R. Sironen, M. J. Lammi, M. B. Goldring, J. E. Eriksson, L. Sistonen, and H. J. Helminen

Hsp70 accumulation in chondrocytic cells exposed to high continuous hydrostatic pressure coincides with mRNA stabilization rather than transcriptional activation
PNAS 1998 95: 2319-2324. [Abstract] [Full Text] [PDF]  

Tae-Yon Chun, David Gregg, Dipak K. Sarkar, and Jack Gorski

Differential regulation by estrogens of growth and prolactin synthesis in pituitary cells suggests that only a small pool of estrogen receptors is required for growth
PNAS 1998 95: 2325-2330. [Abstract] [Full Text] [PDF]  

Andreas R. P. Beck, Ira J. Miller, Paul Anderson, and Michel Streuli

RNA-binding protein TIAR is essential for primordial germ cell development
PNAS 1998 95: 2331-2336. [Abstract] [Full Text] [PDF]  

Michio Suda, Yoshihiro Ogawa, Kiyoshi Tanaka, Naohisa Tamura, Akihiro Yasoda, Toshiya Takigawa, Masahiro Uehira, Hirofumi Nishimoto, Hiroshi Itoh, Yoshihiko Saito, Kohei Shiota, and Kazuwa Nakao

Skeletal overgrowth in transgenic mice that overexpress brain natriuretic peptide
PNAS 1998 95: 2337-2342. [Abstract] [Full Text] [PDF]  

Developmental Biology

Tanja Eggert, Bernd Hauck, Nicole Hildebrandt, Walter J. Gehring, and Uwe Walldorf

Isolation of a Drosophila homolog of the vertebrate homeobox gene Rx and its possible role in brain and eye development
PNAS 1998 95: 2343-2348. [Abstract] [Full Text] [PDF]  

Yang Chen, Nicole Gallaher, Richard H. Goodman, and Sarah M. Smolik

Protein kinase A directly regulates the activity and proteolysis of cubitus interruptus
PNAS 1998 95: 2349-2354. [Abstract] [Full Text] [PDF]  

Evolution

Heinz-Georg Belting, Cooduvalli S. Shashikant, and Frank H. Ruddle

Modification of expression and cis-regulation of Hoxc8 in the evolution of diverged axial morphology
PNAS 1998 95: 2355-2360. [Abstract] [Full Text] [PDF]  

Troy Day and Peter D. Taylor

Chromosomal drive and the evolution of meiotic nondisjunction and trisomy in humans
PNAS 1998 95: 2361-2365. [Abstract] [Full Text] [PDF]  

Fred van Leeuwen, Martin C. Taylor, Angeles Mondragon, Hervé Moreau, Wendy Gibson, Rudo Kieft, and Piet Borst

-D-Glucosyl-hydroxymethyluracil is a conserved DNA modification in kinetoplastid protozoans and is abundant in their telomeres
PNAS 1998 95: 2366-2371. [Abstract] [Full Text] [PDF]  

Lisa M. Kann, Erica B. Rosenblum, and David M. Rand

Aging, mating, and the evolution of mtDNA heteroplasmy in Drosophila melanogaster
PNAS 1998 95: 2372-2377. [Abstract] [Full Text] [PDF]  

Kathleen Szick, Mark Springer, and Julia Bailey-Serres

Evolutionary analyses of the 12-kDa acidic ribosomal P-proteins reveal a distinct protein of higher plant ribosomes
PNAS 1998 95: 2378-2383. [Abstract] [Full Text] [PDF]  

Genetics

Corrella S. Detweiler and Joachim J. Li

Ectopic induction of Clb2 in early G₁ phase is sufficient to block prereplicative complex formation in Saccharomyces cerevisiae
PNAS 1998 95: 2384-2389. [Abstract] [Full Text] [PDF]  

Matthew P. Strout, Guido Marcucci, Clara D. Bloomfield, and Michael A. Caligiuri

The partial tandem duplication of ALL1 (MLL) is consistently generated by Alu-mediated homologous recombination in acute myeloid leukemia
PNAS 1998 95: 2390-2395. [Abstract] [Full Text] [PDF]  

Juergen Bachl, Carina Olsson, Nishay Chitkara, and Matthias Wabl

The Ig mutator is dependent on the presence, position, and orientation of the large intron enhancer
PNAS 1998 95: 2396-2399. [Abstract] [Full Text] [PDF]  

Irina L. Derkatch, Michael E. Bradley, and Susan W. Liebman

Overexpression of the SUP45 gene encoding a Sup35p-binding protein inhibits the induction of the de novo appearance of the [PSI⁺] prion
PNAS 1998 95: 2400-2405. [Abstract] [Full Text] [PDF]  

Rüdiger J. Blaschke, A. Paula Monaghan, Simone Schiller, Birgit Schechinger, Ercole Rao, Hesed Padilla-Nash, Thomas Ried, and Gudrun A. Rappold

SHOT, a SHOX-related homeobox gene, is implicated in craniofacial, brain, heart, and limb development
PNAS 1998 95: 2406-2411. [Abstract] [Full Text] [PDF]  

Shibin Zhou, Phillip Buckhaults, Leigh Zawel, Fred Bunz, Greg Riggins, Jia Le Dai, Scott E. Kern, Kenneth W. Kinzler, and Bert Vogelstein

Targeted deletion of Smad4 shows it is required for transforming growth factor  and activin signaling in colorectal cancer cells
PNAS 1998 95: 2412-2416. [Abstract] [Full Text] [PDF]  

Anuj Kumar and John V. Paietta

An additional role for the F-box motif: Gene regulation within the Neurospora crassa sulfur control network
PNAS 1998 95: 2417-2422. [Abstract] [Full Text] [PDF]  

Stephen W. McKechnie, Michael M. Halford, Gawain McColl, and Ary A. Hoffmann

Both allelic variation and expression of nuclear and cytoplasmic transcripts of Hsr-omega are closely associated with thermal phenotype in Drosophila
PNAS 1998 95: 2423-2428. [Abstract] [Full Text] [PDF]  

Shuling Zhang, Edward S. Ramsay, and Beverly A. Mock

Cdkn2a, the cyclin-dependent kinase inhibitor encoding p16^INK4a and p19^ARF, is a candidate for the plasmacytoma susceptibility locus, Pctr1
PNAS 1998 95: 2429-2434. [Abstract] [Full Text] [PDF]  

Immunology

Oran Ayalon, Eric A. Hughes, Peter Cresswell, Jennifer Lee, Lynn O'Donnell, Ruggero Pardi, and Jeffrey R. Bender

Induction of transporter associated with antigen processing by interferon  confers endothelial cell cytoprotection against natural killer-mediated lysis
PNAS 1998 95: 2435-2440. [Abstract] [Full Text] [PDF]  

Simon P. Hogan, Paul S. Foster, Brett Charlton, and Robyn M. Slattery

Prevention of Th2-mediated murine allergic airways disease by soluble antigen administration in the neonate
PNAS 1998 95: 2441-2445. [Abstract] [Full Text] [PDF]  

Mathieu Bléry, Hiromi Kubagawa, Ching-Cheng Chen, Frédéric Vély, Max D. Cooper, and Eric Vivier

The paired Ig-like receptor PIR-B is an inhibitory receptor that recruits the protein-tyrosine phosphatase SHP-1
PNAS 1998 95: 2446-2451. [Abstract] [Full Text] [PDF]  

Nazli Azimi, Keith Brown, Richard N. Bamford, Yutaka Tagaya, Ulrich Siebenlist, and Thomas A. Waldmann

Human T cell lymphotropic virus type I Tax protein trans-activates interleukin 15 gene transcription through an NF-B site
PNAS 1998 95: 2452-2457. [Abstract] [Full Text] [PDF]  

Holden T. Maecker, Myoung-Sool Do, and Shoshana Levy

CD81 on B cells promotes interleukin 4 secretion and antibody production during T helper type 2 immune responses
PNAS 1998 95: 2458-2462. [Abstract] [Full Text] [PDF]  

Tina Goossens, Ulf Klein, and Ralf Küppers

Frequent occurrence of deletions and duplications during somatic hypermutation: Implications for oncogene translocations and heavy chain disease
PNAS 1998 95: 2463-2468. [Abstract] [Full Text] [PDF]  

Carlos Zaragoza, Christopher Ocampo, Marta Saura, Michelle Leppo, Xiao-Qing Wei, Richard Quick, Salvador Moncada, Foo Y. Liew, and Charles J. Lowenstein

The role of inducible nitric oxide synthase in the host response to Coxsackievirus myocarditis
PNAS 1998 95: 2469-2474. [Abstract] [Full Text] [PDF]  

Holger N. Lode, Torsten Dreier, Rong Xiang, Nissi M. Varki, Angray S. Kang, and Ralph A. Reisfeld

Gene therapy with a single chain interleukin 12 fusion protein induces T cell-dependent protective immunity in a syngeneic model of murine neuroblastoma
PNAS 1998 95: 2475-2480. [Abstract] [Full Text] [PDF]  

Anna Modelska, Bernard Dietzschold, N. Sleysh, Zhen Fang Fu, Klaudia Steplewski, D. Craig Hooper, Hilary Koprowski, and Vidadi Yusibov

Immunization against rabies with plant-derived antigen
PNAS 1998 95: 2481-2485. [Abstract] [Full Text] [PDF]  

Koichi Akashi, Motonari Kondo, and Irving L. Weissman

Two distinct pathways of positive selection for thymocytes
PNAS 1998 95: 2486-2491. [Abstract] [Full Text] [PDF]  

Medical Sciences

Xiao Yan Zhou, Shunji Tomatsu, Robert E. Fleming, Seppo Parkkila, Abdul Waheed, Jinxing Jiang, Ying Fei, Elizabeth M. Brunt, David A. Ruddy, Cynthia E. Prass, Randall C. Schatzman, Rosemary O'Neill, Robert S. Britton, Bruce R. Bacon, and William S. Sly

HFE gene knockout produces mouse model of hereditary hemochromatosis
PNAS 1998 95: 2492-2497. [Abstract] [Full Text] [PDF]  

Michio Shimabukuro, Yan-Ting Zhou, Moshe Levi, and Roger H. Unger

Fatty acid-induced  cell apoptosis: A link between obesity and diabetes
PNAS 1998 95: 2498-2502. [Abstract] [Full Text] [PDF]  

Yujing Liu, Kinuko Suzuki, Jennifer D. Reed, Alexander Grinberg, Heiner Westphal, Alexander Hoffmann, Thomas Döring, Konrad Sandhoff, and Richard L. Proia

Mice with type 2 and 3 Gaucher disease point mutations generated by a single insertion mutagenesis procedure (SIMP)
PNAS 1998 95: 2503-2508. [Abstract] [Full Text] [PDF]  

Tong-Chuan He, Shibin Zhou, Luis T. da Costa, Jian Yu, Kenneth W. Kinzler, and Bert Vogelstein

A simplified system for generating recombinant adenoviruses
PNAS 1998 95: 2509-2514. [Abstract] [Full Text] [PDF]  

Sivaramaprasad Gudi, John P. Nolan, and John A. Frangos

Modulation of GTPase activity of G proteins by fluid shear stress and phospholipid composition
PNAS 1998 95: 2515-2519. [Abstract] [Full Text] [PDF]  

Laura Manuelidis

Vaccination with an attenuated Creutzfeldt-Jakob disease strain prevents expression of a virulent agent
PNAS 1998 95: 2520-2525. [Abstract] [Full Text] [PDF]  

Yoshito Ihara, Masafumi Yoshimura, Eiji Miyoshi, Atsushi Nishikawa, Ahmed S. Sultan, Satoru Toyosawa, Akio Ohnishi, Misao Suzuki, Ken-ichi Yamamura, Naokuni Ijuhin, and Naoyuki Taniguchi

Ectopic expression of N-acetylglucosaminyltransferase III in transgenic hepatocytes disrupts apolipoprotein B secretion and induces aberrant cellular morphology with lipid storage
PNAS 1998 95: 2526-2530. [Abstract] [Full Text] [PDF]  

Rachel A. Watson-Clark, Mona Lisa Banquerigo, Kenneth Shelly, M. Frederick Hawthorne, and Ernest Brahn

Model studies directed toward the application of boron neutron capture therapy to rheumatoid arthritis: Boron delivery by liposomes in rat collagen-induced arthritis
PNAS 1998 95: 2531-2534. [Abstract] [Full Text] [PDF]  

Beth L. Kelly, Karen G. Wolfe, and James M. Roberts

Identification of a substrate-targeting domain in cyclin E necessary for phosphorylation of the retinoblastoma protein
PNAS 1998 95: 2535-2540. [Abstract] [Full Text] [PDF]  

Julio Licinio, André B. Negrão, Christos Mantzoros, Virginia Kaklamani, Ma-Li Wong, Peter B. Bongiorno, Abeda Mulla, Laura Cearnal, Johannes D. Veldhuis, Jeffrey S. Flier, Samuel M. McCann, and Philip W. Gold

Synchronicity of frequently sampled, 24-h concentrations of circulating leptin, luteinizing hormone, and estradiol in healthy women
PNAS 1998 95: 2541-2546. [Abstract] [Full Text] [PDF]  

Paula M. Oliver, Simon W. M. John, Kit E. Purdy, Ron Kim, Nobuyo Maeda, Michael F. Goy, and Oliver Smithies

Natriuretic peptide receptor 1 expression influences blood pressures of mice in a dose-dependent manner
PNAS 1998 95: 2547-2551. [Abstract] [Full Text] [PDF]  

John R. Hagaman, Jeffrey S. Moyer, Eric S. Bachman, Mathilde Sibony, Patricia L. Magyar, Jeffrey E. Welch, Oliver Smithies, John H. Krege, and Deborah A. O'Brien

Angiotensin-converting enzyme and male fertility
PNAS 1998 95: 2552-2557. [Abstract] [Full Text] [PDF]  

Katarzyna Johan, Gunilla Westermark, Ulla Engström, Åsa Gustavsson, Per Hultman, and Per Westermark

Acceleration of amyloid protein A amyloidosis by amyloid-like synthetic fibrils
PNAS 1998 95: 2558-2563. [Abstract] [Full Text] [PDF]  

Microbiology

Lionel Bénard, Nathalie Mathy, Marianne Grunberg-Manago, Bernard Ehresmann, Chantal Ehresmann, and Claude Portier

Identification in a pseudoknot of a U·G motif essential for the regulation of the expression of ribosomal protein S15
PNAS 1998 95: 2564-2567. [Abstract] [Full Text] [PDF]  

Mark Burkart, Adam Toguchi, and Rasika M. Harshey

The chemotaxis system, but not chemotaxis, is essential for swarming motility in Escherichia coli
PNAS 1998 95: 2568-2573. [Abstract] [Full Text] [PDF]  

Wolf-Dietrich Hardt, Henning Urlaub, and Jorge E. Galán

A substrate of the centisome 63 type III protein secretion system of Salmonella typhimurium is encoded by a cryptic bacteriophage
PNAS 1998 95: 2574-2579. [Abstract] [Full Text] [PDF]  

Rachel L. Damico, Joanne Crane, and Paul Bates

Receptor-triggered membrane association of a model retroviral glycoprotein
PNAS 1998 95: 2580-2585. [Abstract] [Full Text] [PDF]  

Neurobiology

Yan Zhang, Li Zhou, and Carol A. Miller

A splicing variant of a death domain protein that is regulated by a mitogen-activated kinase is a substrate for c-Jun N-terminal kinase in the human central nervous system
PNAS 1998 95: 2586-2591. [Abstract] [Full Text] [PDF]  

Leslie A. Krushel, Ming-Hong Tai, Bruce A. Cunningham, Gerald M. Edelman, and Kathryn L. Crossin

Neural cell adhesion molecule (N-CAM) domains and intracellular signaling pathways involved in the inhibition of astrocyte proliferation
PNAS 1998 95: 2592-2596. [Abstract] [Full Text] [PDF]  

Brent D. Holst, Peter W. Vanderklish, Leslie A. Krushel, Wei Zhou, Ronald B. Langdon, John R. McWhirter, Gerald M. Edelman, and Kathryn L. Crossin

Allosteric modulation of AMPA-type glutamate receptors increases activity of the promoter for the neural cell adhesion molecule, N-CAM
PNAS 1998 95: 2597-2602. [Abstract] [Full Text] [PDF]  

U. Blömer, T. Kafri, L. Randolph-Moore, I. M. Verma, and F. H. Gage

Bcl-xL protects adult septal cholinergic neurons from axotomized cell death
PNAS 1998 95: 2603-2608. [Abstract] [Full Text] [PDF]  

Barbara Chapman and Tobias Bonhoeffer

Overrepresentation of horizontal and vertical orientation preferences in developing ferret area 17
PNAS 1998 95: 2609-2614. [Abstract] [Full Text] [PDF]  

Ernst U. Walther, Martin Dichgans, Stephen M. Maricich, Rita R. Romito, Fei Yang, Suzan Dziennis, Saul Zackson, Richard Hawkes, and Karl Herrup

Genomic sequences of aldolase C (Zebrin II) direct lacZ expression exclusively in non-neuronal cells of transgenic mice
PNAS 1998 95: 2615-2620. [Abstract] [Full Text] [PDF]  

David M. Coppola, Leonard E. White, David Fitzpatrick, and Dale Purves

Unequal representation of cardinal and oblique contours in ferret visual cortex
PNAS 1998 95: 2621-2623. [Abstract] [Full Text] [PDF]  

N. Yu, J. N. Billaud, and T. R. Phillips

Effects of feline immunodeficiency virus on astrocyte glutamate uptake: Implications for lentivirus-induced central nervous system diseases
PNAS 1998 95: 2624-2629. [Abstract] [Full Text] [PDF]  

Andreas Zimmer, Anne M. Zimmer, Judith Baffi, Ted Usdin, Kay Reynolds, Monika König, Miklós Palkovits, and Éva Mezey

Hypoalgesia in mice with a targeted deletion of the tachykinin 1 gene
PNAS 1998 95: 2630-2635. [Abstract] [Full Text] [PDF]  

Sally E. Shaywitz, Bennett A. Shaywitz, Kenneth R. Pugh, Robert K. Fulbright, R. Todd Constable, W. Einar Mencl, Donald P. Shankweiler, Alvin M. Liberman, Pawel Skudlarski, Jack M. Fletcher, Leonard Katz, Karen E. Marchione, Cheryl Lacadie, Christopher Gatenby, and John C. Gore

Functional disruption in the organization of the brain for reading in dyslexia
PNAS 1998 95: 2636-2641. [Abstract] [Full Text] [PDF]  

Shigeyuki Nonaka, Christopher J. Hough, and De-Maw Chuang

Chronic lithium treatment robustly protects neurons in the central nervous system against excitotoxicity by inhibiting N-methyl-D-aspartate receptor-mediated calcium influx
PNAS 1998 95: 2642-2647. [Abstract] [Full Text] [PDF]  

Pharmacology

Jianghao Chen, Jeffry A. Bander, Tara Ann Santore, Yibang Chen, Prahlad T. Ram, Martine J. Smit, and Ravi Iyengar

Expression of Q227L-G_s in MCF-7 human breast cancer cells inhibits tumorigenesis
PNAS 1998 95: 2648-2652. [Abstract] [Full Text] [PDF]  

Sho-Ya Wang and Ging Kuo Wang

Point mutations in segment I-S6 render voltage-gated Na⁺ channels resistant to batrachotoxin
PNAS 1998 95: 2653-2658. [Abstract] [Full Text] [PDF]  

Daniela Salvemini, Zhi-Qiang Wang, Michael K. Stern, Mark G. Currie, and Thomas P. Misko

Peroxynitrite decomposition catalysts: Therapeutics for peroxynitrite-mediated pathology
PNAS 1998 95: 2659-2663. [Abstract] [Full Text] [PDF]  

Physiology

Jeffrey R. Martens, Phyllis Y. Reaves, Di Lu, Michael J. Katovich, Kathleen H. Berecek, Sanford P. Bishop, Mohan K. Raizada, and Craig H. Gelband

Prevention of renovascular and cardiac pathophysiological changes in hypertension by angiotensin II type 1 receptor antisense gene therapy
PNAS 1998 95: 2664-2669. [Abstract] [Full Text] [PDF]  

Z. H. Cho, S. C. Chung, J. P. Jones, J. B. Park, H. J. Park, H. J. Lee, E. K. Wong, and B. I. Min

New findings of the correlation between acupoints and corresponding brain cortices using functional MRI
PNAS 1998 95: 2670-2673. [Abstract] [Full Text] [PDF]  

Erik M. Schwiebert, Marcelo M. Morales, Sreenivas Devidas, Marie E. Egan, and William B. Guggino

Chloride channel and chloride conductance regulator domains of CFTR, the cystic fibrosis transmembrane conductance regulator
PNAS 1998 95: 2674-2679. [Abstract] [Full Text] [PDF]  

Yong-Fu Xiao, Sterling N. Wright, Ging Kuo Wang, James P. Morgan, and Alexander Leaf

Fatty acids suppress voltage-gated Na⁺ currents in HEK293t cells transfected with the -subunit of the human cardiac Na⁺ channel
PNAS 1998 95: 2680-2685. [Abstract] [Full Text] [PDF]  

Plant Biology

Chentao Lin, Hongyun Yang, Hongwei Guo, Todd Mockler, Jeff Chen, and Anthony R. Cashmore

Enhancement of blue-light sensitivity of Arabidopsis seedlings by a blue light receptor cryptochrome 2
PNAS 1998 95: 2686-2690. [Abstract] [Full Text] [PDF]  

Aya Imamura, Naoto Hanaki, Hiroyuki Umeda, Ayako Nakamura, Tomomi Suzuki, Chiharu Ueguchi, and Takeshi Mizuno

Response regulators implicated in His-to-Asp phosphotransfer signaling in Arabidopsis
PNAS 1998 95: 2691-2696. [Abstract] [Full Text] [PDF]  

Sian Ritchie and Simon Gilroy

Abscisic acid signal transduction in the barley aleurone is mediated by phospholipase D activity
PNAS 1998 95: 2697-2702. [Abstract] [Full Text] [PDF]  

Psychology

Cheryl L. Grady, Anthony R. McIntosh, M. Natasha Rajah, and Fergus I. M. Craik

Neural correlates of the episodic encoding of pictures and words
PNAS 1998 95: 2703-2708. [Abstract] [Full Text] [PDF]  

Dennis McFadden and Edward G. Pasanen

Comparison of the auditory systems of heterosexuals and homosexuals: Click-evoked otoacoustic emissions
PNAS 1998 95: 2709-2713. [Abstract] [Full Text] [PDF]  

CORRECTIONS

Correction for vol. 94, p. 11792 [Full Text]  

Correction for vol. 94, p. 14042 [Full Text]  

Correction for vol. 94, p. 13273 [Full Text]  

Correction for vol. 94, p. 12792 [Full Text]