COMMENTARIES

Eric S. Haag

Rolling back to BOULE
PNAS 2001 98: 6983-6985. [Full Text] [PDF]  

Richard E. Dickerson and Ho-Leung Ng

DNA structure from A to B
PNAS 2001 98: 6986-6988. [Full Text] [PDF]  

Donald MacGlashan Jr.

Signaling cascades: Escape from kinetic proofreading
PNAS 2001 98: 6989-6990. [Full Text] [PDF]  

Stephen H. Hughes

Molecular matchmaking: NNRTIs can enhance the dimerization of HIV type 1 reverse transcriptase
PNAS 2001 98: 6991-6992. [Full Text] [PDF]  

COLLOQUIUM:
Papers from the National Academy of Sciences Colloquium on Molecular Kinesis in Cellular Function and Plasticity

Henri Tiedge, Floyd E. Bloom, and Dietmar Richter

Molecular kinesis in cellular function and plasticity
PNAS 2001 98: 6997-6998. [Abstract] [Full Text] [PDF]  

Lawrence S. B. Goldstein

Kinesin molecular motors: Transport pathways, receptors, and human disease
PNAS 2001 98: 6999-7003. [Abstract] [Full Text] [PDF]  

Harukata Miki, Mitsutoshi Setou, Kiyofumi Kaneshiro, and Nobutaka Hirokawa

All kinesin superfamily protein, KIF, genes in mouse and human
PNAS 2001 98: 7004-7011. [Abstract] [Full Text] [PDF] [Data Supplement]  

Bertil Daneholt

Assembly and transport of a premessenger RNP particle
PNAS 2001 98: 7012-7017. [Abstract] [Full Text] [PDF]  

Jack D. Keene

Ribonucleoprotein infrastructure regulating the flow of genetic information between the genome and the proteome
PNAS 2001 98: 7018-7024. [Abstract] [Full Text] [PDF]  

Arash Bashirullah, Ramona L. Cooperstock, and Howard D. Lipshitz

Spatial and temporal control of RNA stability
PNAS 2001 98: 7025-7028. [Abstract] [Full Text] [PDF]  

Tatyana V. Pestova, Victoria G. Kolupaeva, Ivan B. Lomakin, Evgeny V. Pilipenko, Ivan N. Shatsky, Vadim I. Agol, and Christopher U. T. Hellen

Molecular mechanisms of translation initiation in eukaryotes
PNAS 2001 98: 7029-7036. [Abstract] [Full Text] [PDF]  

Brian Raught, Anne-Claude Gingras, and Nahum Sonenberg

The target of rapamycin (TOR) proteins
PNAS 2001 98: 7037-7044. [Abstract] [Full Text] [PDF]  

Elena A. Shestakova, Robert H. Singer, and John Condeelis

The physiological significance of -actin mRNA localization in determining cell polarity and directional motility
PNAS 2001 98: 7045-7050. [Abstract] [Full Text] [PDF]  

M. A. Silverman, S. Kaech, M. Jareb, M. A. Burack, L. Vogt, P. Sonderegger, and G. Banker

Sorting and directed transport of membrane proteins during development of hippocampal neurons in culture
PNAS 2001 98: 7051-7057. [Abstract] [Full Text] [PDF] [Supplemental Data]  

Morgan Sheng

Molecular organization of the postsynaptic specialization
PNAS 2001 98: 7058-7061. [Abstract] [Full Text] [PDF]  

Oswald Steward and Paul F. Worley

A cellular mechanism for targeting newly synthesized mRNAs to synaptic sites on dendrites
PNAS 2001 98: 7062-7068. [Abstract] [Full Text] [PDF]  

Joel D. Richter

Think globally, translate locally: What mitotic spindles and neuronal synapses have in common
PNAS 2001 98: 7069-7071. [Abstract] [Full Text] [PDF]  

Evita Mohr, Nilima Prakash, Kerstin Vieluf, Carola Fuhrmann, Friedrich Buck, and Dietmar Richter

Vasopressin mRNA localization in nerve cells: Characterization of cis-acting elements and trans-acting factors
PNAS 2001 98: 7072-7079. [Abstract] [Full Text] [PDF]  

James Eberwine, Kevin Miyashiro, Janet Estee Kacharmina, and Christy Job

Local translation of classes of mRNAs that are targeted to neuronal dendrites
PNAS 2001 98: 7080-7085. [Abstract] [Full Text] [PDF]  

Stefanie Kaech, Hema Parmar, Martijn Roelandse, Caroline Bornmann, and Andrew Matus

Cytoskeletal microdifferentiation: A mechanism for organizing morphological plasticity in dendrites
PNAS 2001 98: 7086-7092. [Abstract] [Full Text] [PDF] [Supplemental Movie]  

Bruce McEwen, Keith Akama, Stephen Alves, Wayne G. Brake, Karen Bulloch, Susan Lee, Chenjian Li, Genevieve Yuen, and Teresa A. Milner

Tracking the estrogen receptor in neurons: Implications for estrogen-induced synapse formation
PNAS 2001 98: 7093-7100. [Abstract] [Full Text] [PDF]  

William T. Greenough, Anna Y. Klintsova, Scott A. Irwin, Roberto Galvez, Kathy E. Bates, and Ivan Jeanne Weiler

Synaptic regulation of protein synthesis and the fragile X protein
PNAS 2001 98: 7101-7106. [Abstract] [Full Text] [PDF]  

PERSPECTIVES

Mary C. Stiner

Thirty years on the "Broad Spectrum Revolution" and paleolithic demography
PNAS 2001 98: 6993-6996; published online before print June 5, 2001, 10.1073/pnas.121176198 [Full Text] [PDF]  

PHYSICAL SCIENCES
Applied Mathematics

Chi-Sang Poon and Mauricio Barahona

Titration of chaos with added noise
PNAS 2001 98: 7107-7112. [Abstract] [Full Text] [PDF]  

Applied Physical Sciences

A. Wang, J. R. Babcock, N. L. Edleman, A. W. Metz, M. A. Lane, R. Asahi, V. P. Dravid, C. R. Kannewurf, A. J. Freeman, and T. J. Marks

Indium-cadmium-oxide films having exceptional electrical conductivity and optical transparency: Clues for optimizing transparent conductors
PNAS 2001 98: 7113-7116. [Abstract] [Full Text] [PDF]  

Chemistry

Chong-Yu Ruan, Vladimir A. Lobastov, Ramesh Srinivasan, Boyd M. Goodson, Hyotcherl Ihee, and Ahmed H. Zewail

Ultrafast diffraction and structural dynamics: The nature of complex molecules far from equilibrium
PNAS 2001 98: 7117-7122; published online before print June 12, 2001, 10.1073/pnas.131192898 [Abstract] [Full Text] [PDF]  

Geology

Richard Reynolds, Jayne Belnap, Marith Reheis, Paul Lamothe, and Fred Luiszer From the Cover: Aeolian dust in Colorado Plateau soils: Nutrient inputs and recent change in source PNAS 2001 98: 7123-7127; published online before print June 5, 2001, 10.1073/pnas.121094298 [Abstract] [Full Text] [PDF] [Supplemental Data]

Mathematics

J. E. Truscott and C. A. Gilligan

The effect of cultivation on the size, shape, and persistence of disease patches in fields
PNAS 2001 98: 7128-7133. [Abstract] [Full Text] [PDF] [Supplemental Appendix]  

SOCIAL SCIENCES
Anthropology

Mary C. Stiner

Thirty years on the "Broad Spectrum Revolution" and paleolithic demography
PNAS 2001 98: 6993-6996; published online before print June 5, 2001, 10.1073/pnas.121176198 [Full Text] [PDF]  

Steven L. Kuhn, Mary C. Stiner, David S. Reese, and Erksin Güleç

Ornaments of the earliest Upper Paleolithic: New insights from the Levant
PNAS 2001 98: 7641-7646; published online before print June 5, 2001, 10.1073/pnas.121590798 [Abstract] [Full Text] [PDF]  

BIOLOGICAL SCIENCES
Agricultural Sciences

J. E. Truscott and C. A. Gilligan

The effect of cultivation on the size, shape, and persistence of disease patches in fields
PNAS 2001 98: 7128-7133. [Abstract] [Full Text] [PDF] [Supplemental Appendix]  

Biochemistry

Martin Sagermann, Tom H. Stevens, and Brian W. Matthews

Crystal structure of the regulatory subunit H of the V-type ATPase of Saccharomyces cerevisiae
PNAS 2001 98: 7134-7139. [Abstract] [Full Text] [PDF]  

Kenneth A. Simmen, Jasbir Singh, B. G. Mattias Luukkonen, Matt Lopper, Anton Bittner, Nancy E. Miller, Michael R. Jackson, Teresa Compton, and Klaus Früh

Global modulation of cellular transcription by human cytomegalovirus is initiated by viral glycoprotein B
PNAS 2001 98: 7140-7145; published online before print June 5, 2001, 10.1073/pnas.121177598 [Abstract] [Full Text] [PDF] [Supplemental Tables]  

Sisi Marcondes, Illarion V. Turko, and Ferid Murad

Nitration of succinyl-CoA:3-oxoacid CoA-transferase in rats after endotoxin administration
PNAS 2001 98: 7146-7151. [Abstract] [Full Text] [PDF]  

Pavlina T. Ivanova, Blas A. Cerda, David M. Horn, Jared S. Cohen, Fred W. McLafferty, and H. Alex Brown

Electrospray ionization mass spectrometry analysis of changes in phospholipids in RBL-2H3 mastocytoma cells during degranulation
PNAS 2001 98: 7152-7157. [Abstract] [Full Text] [PDF]  

Martha L. Bulyk, Xiaohua Huang, Yen Choo, and George M. Church

Exploring the DNA-binding specificities of zinc fingers with DNA microarrays
PNAS 2001 98: 7158-7163; published online before print June 12, 2001, 10.1073/pnas.111163698 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Giancarlo Marra, Stefania D'Atri, Chantal Corti, Laura Bonmassar, Maria Sofia Cattaruzza, Pascal Schweizer, Karl Heinimann, Zdena Bartosova, Minna Nyström-Lahti, and Josef Jiricny

Tolerance of human MSH2^+/ lymphoblastoid cells to the methylating agent temozolomide
PNAS 2001 98: 7164-7169. [Abstract] [Full Text] [PDF]  

Jesús R. Requena, Darlene Groth, Giuseppe Legname, Earl R. Stadtman, Stanley B. Prusiner, and Rodney L. Levine

Copper-catalyzed oxidation of the recombinant SHa(29-231) prion protein
PNAS 2001 98: 7170-7175; published online before print June 12, 2001, 10.1073/pnas.121190898 [Abstract] [Full Text] [PDF]  

Byung-Taek Kim, Hiroshi Kitagawa, Jun-ichi Tamura, Toshiyuki Saito, Marion Kusche-Gullberg, Ulf Lindahl, and Kazuyuki Sugahara

Human tumor suppressor EXT gene family members EXTL1 and EXTL3 encode 1,4- N-acetylglucosaminyltransferases that likely are involved in heparan sulfate/ heparin biosynthesis
PNAS 2001 98: 7176-7181; published online before print June 5, 2001, 10.1073/pnas.131188498 [Abstract] [Full Text] [PDF]  

Omar A. Ibrahimi, Anna V. Eliseenkova, Alexander N. Plotnikov, Kai Yu, David M. Ornitz, and Moosa Mohammadi

Structural basis for fibroblast growth factor receptor 2 activation in Apert syndrome
PNAS 2001 98: 7182-7187; published online before print June 5, 2001, 10.1073/pnas.121183798 [Abstract] [Full Text] [PDF]  

Gilda Tachedjian, Marianna Orlova, Stefan G. Sarafianos, Edward Arnold, and Stephen P. Goff From the Cover: Nonnucleoside reverse transcriptase inhibitors are chemical enhancers of dimerization of the HIV type 1 reverse transcriptase PNAS 2001 98: 7188-7193. [Abstract] [Full Text] [PDF]

Alireza Aslani, Bertil Macao, Stina Simonsson, and Per Elias

Complementary intrastrand base pairing during initiation of Herpes simplex virus type 1 DNA replication
PNAS 2001 98: 7194-7199. [Abstract] [Full Text] [PDF]  

Hui-Kuan Lin, Shuyuan Yeh, Hong-Yo Kang, and Chawnshang Chang

Akt suppresses androgen-induced apoptosis by phosphorylating and inhibiting androgen receptor
PNAS 2001 98: 7200-7205; published online before print June 12, 2001, 10.1073/pnas.121173298 [Abstract] [Full Text] [PDF]  

Corinne Sagné, Cendra Agulhon, Philippe Ravassard, Michèle Darmon, Michel Hamon, Salah El Mestikawy, Bruno Gasnier, and Bruno Giros

Identification and characterization of a lysosomal transporter for small neutral amino acids
PNAS 2001 98: 7206-7211; published online before print June 5, 2001, 10.1073/pnas.121183498 [Abstract] [Full Text] [PDF]  

Sruti Shiva, Paul S. Brookes, Rakesh P. Patel, Peter G. Anderson, and Victor M. Darley-Usmar

Nitric oxide partitioning into mitochondrial membranes and the control of respiration at cytochrome c oxidase
PNAS 2001 98: 7212-7217. [Abstract] [Full Text] [PDF]  

Yanwen Chen, Sean S. Molloy, Laurel Thomas, Jay Gambee, Hans Peter Bächinger, Betsy Ferguson, Jonathan Zonana, Gary Thomas, and Nicholas P. Morris

Mutations within a furin consensus sequence block proteolytic release of ectodysplasin-A and cause X-linked hypohidrotic ectodermal dysplasia
PNAS 2001 98: 7218-7223. [Abstract] [Full Text] [PDF]  

Boris Illarionov, Wolfgang Eisenreich, and Adelbert Bacher

A pentacyclic reaction intermediate of riboflavin synthase
PNAS 2001 98: 7224-7229; published online before print June 12, 2001, 10.1073/pnas.131610698 [Abstract] [Full Text] [PDF]  

Hiroshi Mizuno, Zui Fujimoto, Hideko Atoda, and Takashi Morita

Crystal structure of an anticoagulant protein in complex with the Gla domain of factor X
PNAS 2001 98: 7230-7234; published online before print June 12, 2001, 10.1073/pnas.131179698 [Abstract] [Full Text] [PDF]  

Biophysics

Chi-Sang Poon and Mauricio Barahona

Titration of chaos with added noise
PNAS 2001 98: 7107-7112. [Abstract] [Full Text] [PDF]  

Peter I. Kuzmin, Joshua Zimmerberg, Yuri A. Chizmadzhev, and Fredric S. Cohen

A quantitative model for membrane fusion based on low-energy intermediates
PNAS 2001 98: 7235-7240; published online before print June 12, 2001, 10.1073/pnas.121191898 [Abstract] [Full Text] [PDF]  

Shikha Arora, Philip Edward Lapinski, and Malini Raghavan

Use of chimeric proteins to investigate the role of transporter associated with antigen processing (TAP) structural domains in peptide binding and translocation
PNAS 2001 98: 7241-7246. [Abstract] [Full Text] [PDF] [Supplemental Data]  

H. Salman, D. Zbaida, Y. Rabin, D. Chatenay, and M. Elbaum

Kinetics and mechanism of DNA uptake into the cell nucleus
PNAS 2001 98: 7247-7252; published online before print June 5, 2001, 10.1073/pnas.121067698 [Abstract] [Full Text] [PDF]  

Robert K. Adair

Simple neural networks for the amplification and utilization of small changes in neuron firing rates
PNAS 2001 98: 7253-7258; published online before print June 12, 2001, 10.1073/pnas.121171598 [Abstract] [Full Text] [PDF]  

Jonathan N. Webb, Serena D. Webb, Jeffrey L. Cleland, John F. Carpenter, and Theodore W. Randolph

Partial molar volume, surface area, and hydration changes for equilibrium unfolding and formation of aggregation transition state: High-pressure and cosolute studies on recombinant human IFN-
PNAS 2001 98: 7259-7264; published online before print May 29, 2001, 10.1073/pnas.131194798 [Abstract] [Full Text] [PDF]  

Jeffrey M. Vargason, Keith Henderson, and P. Shing Ho From the Cover: A crystallographic map of the transition from B-DNA to A-DNA PNAS 2001 98: 7265-7270; published online before print June 5, 2001, 10.1073/pnas.121176898 [Abstract] [Full Text] [PDF] [Supplemental Movies]

Cell Biology

Anja Lührmann, Karin Streker, Anja Schüttfort, Justin J. D. Daniels, and Albert Haas

Afipia felis induces uptake by macrophages directly into a nonendocytic compartment
PNAS 2001 98: 7271-7276; published online before print June 12, 2001, 10.1073/pnas.121190398 [Abstract] [Full Text] [PDF]  

Olga I. Stenina, Kristin M. Shaneyfelt, and Paul E. DiCorleto

Thrombin induces the release of the Y-box protein dbpB from mRNA: A mechanism of transcriptional activation
PNAS 2001 98: 7277-7282; published online before print June 5, 2001, 10.1073/pnas.121592298 [Abstract] [Full Text] [PDF]  

Finny G. Kuruvilla, Alykhan F. Shamji, and Stuart L. Schreiber

Carbon- and nitrogen-quality signaling to translation are mediated by distinct GATA-type transcription factors
PNAS 2001 98: 7283-7288. [Abstract] [Full Text] [PDF]  

Zhao-Jun Liu, Hana Haleem-Smith, Huaxian Chen, and Henry Metzger From the Cover: Unexpected signals in a system subject to kinetic proofreading PNAS 2001 98: 7289-7294; published online before print May 22, 2001, 10.1073/pnas.121171998 [Abstract] [Full Text] [PDF]

William S. Hlavacek, Antonio Redondo, Henry Metzger, Carla Wofsy, and Byron Goldstein

Kinetic proofreading models for cell signaling predict ways to escape kinetic proofreading
PNAS 2001 98: 7295-7300; published online before print June 5, 2001, 10.1073/pnas.121172298 [Abstract] [Full Text] [PDF]  

Lucía Piacenza, Gonzalo Peluffo, and Rafael Radi

L-Arginine-dependent suppression of apoptosis in Trypanosoma cruzi: Contribution of the nitric oxide and polyamine pathways
PNAS 2001 98: 7301-7306; published online before print June 12, 2001, 10.1073/pnas.121520398 [Abstract] [Full Text] [PDF]  

David F. Holmes, Christopher J. Gilpin, Clair Baldock, Ulrike Ziese, Abraham J. Koster, and Karl E. Kadler

Corneal collagen fibril structure in three dimensions: Structural insights into fibril assembly, mechanical properties, and tissue organization
PNAS 2001 98: 7307-7312; published online before print June 5, 2001, 10.1073/pnas.111150598 [Abstract] [Full Text] [PDF]  

Eleanor W. Trotter, Lumilla Berenfeld, Sue Ann Krause, Gregory A. Petsko, and Joseph V. Gray

Protein misfolding and temperature up-shift cause G₁ arrest via a common mechanism dependent on heat shock factor in Saccharomyces cerevisiae
PNAS 2001 98: 7313-7318. [Abstract] [Full Text] [PDF]  

Tammy Bowman, Martin A. Broome, Dominic Sinibaldi, Walker Wharton, W. J. Pledger, John M. Sedivy, Rosalyn Irby, Timothy Yeatman, Sara A. Courtneidge, and Richard Jove

Stat3-mediated Myc expression is required for Src transformation and PDGF-induced mitogenesis
PNAS 2001 98: 7319-7324; published online before print June 12, 2001, 10.1073/pnas.131568898 [Abstract] [Full Text] [PDF]  

Angie S. Mah, Joanne Jang, and Raymond J. Deshaies

Protein kinase Cdc15 activates the Dbf2-Mob1 kinase complex
PNAS 2001 98: 7325-7330; published online before print June 12, 2001, 10.1073/pnas.141098998 [Abstract] [Full Text] [PDF]  

Developmental Biology

Pamela A. Padilla and Mark B. Roth

Oxygen deprivation causes suspended animation in the zebrafish embryo
PNAS 2001 98: 7331-7335; published online before print June 12, 2001, 10.1073/pnas.131213198 [Abstract] [Full Text] [PDF]  

C. Blin-Wakkach, F. Lezot, S. Ghoul-Mazgar, D. Hotton, S. Monteiro, C. Teillaud, L. Pibouin, S. Orestes-Cardoso, P. Papagerakis, M. Macdougall, B. Robert, and A. Berdal

Endogenous Msx1 antisense transcript: In vivo and in vitro evidences, structure, and potential involvement in skeleton development in mammals
PNAS 2001 98: 7336-7341; published online before print June 5, 2001, 10.1073/pnas.131497098 [Abstract] [Full Text] [PDF]  

Nancy Fossett, Sergei G. Tevosian, Kathleen Gajewski, Qian Zhang, Stuart H. Orkin, and Robert A. Schulz

The Friend of GATA proteins U-shaped, FOG-1, and FOG-2 function as negative regulators of blood, heart, and eye development in Drosophila
PNAS 2001 98: 7342-7347; published online before print June 12, 2001, 10.1073/pnas.131215798 [Abstract] [Full Text] [PDF]  

Haochu Huang, Liquan Cai, Benjamin F. Remo, and Donald D. Brown

Timing of metamorphosis and the onset of the negative feedback loop between the thyroid gland and the pituitary is controlled by type II iodothyronine deiodinase in Xenopus laevis
PNAS 2001 98: 7348-7353; published online before print June 12, 2001, 10.1073/pnas.131198998 [Abstract] [Full Text] [PDF]  

Chun Li Zhang, Timothy A. McKinsey, and Eric N. Olson

The transcriptional corepressor MITR is a signal-responsive inhibitor of myogenesis
PNAS 2001 98: 7354-7359; published online before print June 5, 2001, 10.1073/pnas.131198498 [Abstract] [Full Text] [PDF]  

Marta Kostrouchova, Michael Krause, Zdenek Kostrouch, and Joseph Edward Rall

Nuclear hormone receptor CHR3 is a critical regulator of all four larval molts of the nematode Caenorhabditis elegans
PNAS 2001 98: 7360-7365. [Abstract] [Full Text] [PDF]  

Ecology

L. Michael Romero and Martin Wikelski

Corticosterone levels predict survival probabilities of Galápagos marine iguanas during El Niño events
PNAS 2001 98: 7366-7370. [Abstract] [Full Text] [PDF]  

Kirsten Pohlmann, Frank W. Grasso, and Thomas Breithaupt

Tracking wakes: The nocturnal predatory strategy of piscivorous catfish
PNAS 2001 98: 7371-7374; published online before print June 5, 2001, 10.1073/pnas.121026298 [Abstract] [Full Text] [PDF]  

Evolution

Willie J. Swanson, Andrew G. Clark, Heidi M. Waldrip-Dail, Mariana F. Wolfner, and Charles F. Aquadro

Evolutionary EST analysis identifies rapidly evolving male reproductive proteins in Drosophila
PNAS 2001 98: 7375-7379; published online before print June 12, 2001, 10.1073/pnas.131568198 [Abstract] [Full Text] [PDF] [Supplemental Table]  

Rafael Zardoya and Axel Meyer

On the origin of and phylogenetic relationships among living amphibians
PNAS 2001 98: 7380-7383; published online before print June 5, 2001, 10.1073/pnas.111455498 [Abstract] [Full Text] [PDF]  

Masato Nikaido, Fumio Matsuno, Healy Hamilton, Robert L. Brownell Jr., Ying Cao, Wang Ding, Zhu Zuoyan, Andrew M. Shedlock, R. Ewan Fordyce, Masami Hasegawa, and Norihiro Okada

Retroposon analysis of major cetacean lineages: The monophyly of toothed whales and the paraphyly of river dolphins
PNAS 2001 98: 7384-7389. [Abstract] [Full Text] [PDF]  

Robert P. Lane, Tyler Cutforth, Janet Young, Maria Athanasiou, Cynthia Friedman, Lee Rowen, Glen Evans, Richard Axel, Leroy Hood, and Barbara J. Trask

Genomic analysis of orthologous mouse and human olfactory receptor loci
PNAS 2001 98: 7390-7395. [Abstract] [Full Text] [PDF]  

Carlos A. Machado and Francisco J. Ayala

Nucleotide sequences provide evidence of genetic exchange among distantly related lineages of Trypanosoma cruzi
PNAS 2001 98: 7396-7401. [Abstract] [Full Text] [PDF]  

Genetics

Katerina Manolakou, Jenny Beaton, Irene McConnell, Christine Farquar, Jean Manson, Nicholas D. Hastie, Moira Bruce, and Ian J. Jackson

Genetic and environmental factors modify bovine spongiform encephalopathy incubation period in mice
PNAS 2001 98: 7402-7407; published online before print June 12, 2001, 10.1073/pnas.121172098 [Abstract] [Full Text] [PDF]  

Ping Cheng, Yuhong Yang, and Yi Liu

Interlocked feedback loops contribute to the robustness of the Neurospora circadian clock
PNAS 2001 98: 7408-7413. [Abstract] [Full Text] [PDF]  

Eugene Yujun Xu, Frederick L. Moore, and Renee A. Reijo Pera From the Cover: A gene family required for human germ cell development evolved from an ancient meiotic gene conserved in metazoans PNAS 2001 98: 7414-7419; published online before print June 5, 2001, 10.1073/pnas.131090498 [Abstract] [Full Text] [PDF]

Ramamurthy Mahalingam and Nina Fedoroff

Screening insertion libraries for mutations in many genes simultaneously using DNA microarrays
PNAS 2001 98: 7420-7425. [Abstract] [Full Text] [PDF]  

Jeffrey O. Blaisdell and Susan S. Wallace

Abortive base-excision repair of radiation-induced clustered DNA lesions in Escherichia coli
PNAS 2001 98: 7426-7430; published online before print June 12, 2001, 10.1073/pnas.131077798 [Abstract] [Full Text] [PDF]  

Immunology

Jaana T. Karttunen, Paul J. Lehner, Soma Sen Gupta, Eric W. Hewitt, and Peter Cresswell

Distinct functions and cooperative interaction of the subunits of the transporter associated with antigen processing (TAP)
PNAS 2001 98: 7431-7436; published online before print May 29, 2001, 10.1073/pnas.121180198 [Abstract] [Full Text] [PDF]  

Madelon M. Maurice, Dina S. Gould, John Carroll, Yulia Vugmeyster, and Hidde L. Ploegh

Positive selection of an MHC class-I restricted TCR in the absence of classical MHC class I molecules
PNAS 2001 98: 7437-7442; published online before print June 12, 2001, 10.1073/pnas.141143298 [Abstract] [Full Text] [PDF]  

Brian Cao, Yanli Su, Marianne Oskarsson, Ping Zhao, Eric J. Kort, Robert J. Fisher, Ling-Mei Wang, and George F. Vande Woude

Neutralizing monoclonal antibodies to hepatocyte growth factor/scatter factor (HGF/SF) display antitumor activity in animal models
PNAS 2001 98: 7443-7448. [Abstract] [Full Text] [PDF]  

Michael J. Czar, Ellen N. Kersh, Lilia A. Mijares, Gibson Lanier, Jennifer Lewis, George Yap, Amy Chen, Alan Sher, Colin S. Duckett, Rafi Ahmed, and Pamela L. Schwartzberg

Altered lymphocyte responses and cytokine production in mice deficient in the X-linked lymphoproliferative disease gene SH2D1A/DSHP/SAP
PNAS 2001 98: 7449-7454; published online before print June 12, 2001, 10.1073/pnas.131193098 [Abstract] [Full Text] [PDF] [Supplemental Tables]  

Sussan Dejbakhsh-Jones, Marcos E. García-Ojeda, Devavani Chatterjea-Matthes, Defu Zeng, and Samuel Strober

Clonable progenitors committed to the T lymphocyte lineage in the mouse bone marrow; use of an extrathymic pathway
PNAS 2001 98: 7455-7460; published online before print June 5, 2001, 10.1073/pnas.131559798 [Abstract] [Full Text] [PDF]  

Charles A. Janeway Jr. INAUGURAL ARTICLE by a Recently Elected Academy Member: Inaugural Article: How the immune system works to protect the host from infection: A personal view PNAS 2001 98: 7461-7468; published online before print June 5, 2001, 10.1073/pnas.131202998 [Full Text] [PDF]

Medical Sciences

Haisong Ju, Robert Gros, Xiaomang You, Sarah Tsang, Mansoor Husain, and Marlene Rabinovitch

Conditional and targeted overexpression of vascular chymase causes hypertension in transgenic mice
PNAS 2001 98: 7469-7474. [Abstract] [Full Text] [PDF]  

Sarah N. Flier, Rohit N. Kulkarni, and C. Ronald Kahn

Evidence for a circulating islet cell growth factor in insulin-resistant states
PNAS 2001 98: 7475-7480; published online before print June 12, 2001, 10.1073/pnas.131192998 [Abstract] [Full Text] [PDF]  

Alex K. Wong, Myra Alfert, Diego H. Castrillon, Qiong Shen, Jocelyn Holash, George D. Yancopoulos, and Lynda Chin

Excessive tumor-elaborated VEGF and its neutralization define a lethal paraneoplastic syndrome
PNAS 2001 98: 7481-7486; published online before print June 12, 2001, 10.1073/pnas.121192298 [Abstract] [Full Text] [PDF]  

Brandon K. Hadland, Nancy R. Manley, Dong-ming Su, Gregory D. Longmore, Chad L. Moore, Michael S. Wolfe, Eric H. Schroeter, and Raphael Kopan

-Secretase inhibitors repress thymocyte development
PNAS 2001 98: 7487-7491. [Abstract] [Full Text] [PDF]  

Xiao-Feng Yang, Catherine J. Wu, Stephen McLaughlin, Antoinette Chillemi, Kathy S. Wang, Christine Canning, Edwin P. Alyea, Philip Kantoff, Robert J. Soiffer, Glenn Dranoff, and Jerome Ritz

CML66, a broadly immunogenic tumor antigen, elicits a humoral immune response associated with remission of chronic myelogenous leukemia
PNAS 2001 98: 7492-7497. [Abstract] [Full Text] [PDF]  

Dibyendu K. Panda, Dengshun Miao, Michel L. Tremblay, Jacinthe Sirois, Riaz Farookhi, Geoffrey N. Hendy, and David Goltzman

Targeted ablation of the 25-hydroxyvitamin D 1-hydroxylase enzyme: Evidence for skeletal, reproductive, and immune dysfunction
PNAS 2001 98: 7498-7503. [Abstract] [Full Text] [PDF] [Supplemental Data]  

Koen Dreijerink, Eleonora Braga, Igor Kuzmin, Laura Geil, Fuh-Mei Duh, Debora Angeloni, Berton Zbar, Michael I. Lerman, Eric J. Stanbridge, John D. Minna, Alexei Protopopov, Jingfeng Li, Vladimir Kashuba, George Klein, and Eugene R. Zabarovsky

The candidate tumor suppressor gene, RASSF1A, from human chromosome 3p21.3 is involved in kidney tumorigenesis
PNAS 2001 98: 7504-7509; published online before print June 5, 2001, 10.1073/pnas.131216298 [Abstract] [Full Text] [PDF] [Supplemental Figures]  

Guangming Liu, Douglas M. Bibus, Ann M. Bode, Wei-Ya Ma, Ralph T. Holman, and Zigang Dong

Omega 3 but not omega 6 fatty acids inhibit AP-1 activity and cell transformation in JB6 cells
PNAS 2001 98: 7510-7515. [Abstract] [Full Text] [PDF]  

Olga Camacho Vanegas, Enrico Bertini, Rui-Zhu Zhang, Stefania Petrini, Claudia Minosse, Patrizia Sabatelli, Betti Giusti, Mon-Li Chu, and Guglielmina Pepe

Ullrich scleroatonic muscular dystrophy is caused by recessive mutations in collagen type VI
PNAS 2001 98: 7516-7521; published online before print May 29, 2001, 10.1073/pnas.121027598 [Abstract] [Full Text] [PDF]  

Jason K. Kim, Jonathan J. Fillmore, Yan Chen, Chunli Yu, Irene K. Moore, Marc Pypaert, E. Peer Lutz, Yuko Kako, Wanda Velez-Carrasco, Ira J. Goldberg, Jan L. Breslow, and Gerald I. Shulman

Tissue-specific overexpression of lipoprotein lipase causes tissue-specific insulin resistance
PNAS 2001 98: 7522-7527; published online before print June 5, 2001, 10.1073/pnas.121164498 [Abstract] [Full Text] [PDF]  

Doron Shabat, Holger N. Lode, Ursula Pertl, Ralph A. Reisfeld, Christoph Rader, Richard A. Lerner, and Carlos F. Barbas III

In vivo activity in a catalytic antibody-prodrug system: Antibody catalyzed etoposide prodrug activation for selective chemotherapy
PNAS 2001 98: 7528-7533; published online before print June 12, 2001, 10.1073/pnas.131187998 [Abstract] [Full Text] [PDF]  

Microbiology

David R. Sherman, Martin Voskuil, Dirk Schnappinger, Reiling Liao, Maria I. Harrell, and Gary K. Schoolnik

Regulation of the Mycobacterium tuberculosis hypoxic response gene encoding -crystallin
PNAS 2001 98: 7534-7539. [Abstract] [Full Text] [PDF]  

Devaki Bhaya, Akiko Takahashi, and Arthur R. Grossman

Light regulation of type IV pilus-dependent motility by chemosensor-like elements in Synechocystis PCC6803
PNAS 2001 98: 7540-7545; published online before print June 12, 2001, 10.1073/pnas.131201098 [Abstract] [Full Text] [PDF]  

Leyla Akman and Serap Aksoy

A novel application of gene arrays: Escherichia coli array provides insight into the biology of the obligate endosymbiont of tsetse flies
PNAS 2001 98: 7546-7551; published online before print June 12, 2001, 10.1073/pnas.131057498 [Abstract] [Full Text] [PDF] [Supplemental Table]  

Sean D. Reid, Nicole M. Green, Julie K. Buss, Benfang Lei, and James M. Musser

Multilocus analysis of extracellular putative virulence proteins made by group A Streptococcus: Population genetics, human serologic response, and gene transcription
PNAS 2001 98: 7552-7557. [Abstract] [Full Text] [PDF] [Supplemental Data]  

Neurobiology

Cheol Kyu Hwang, Ursula M. D'Souza, Amelia J. Eisch, Shunsuke Yajima, Claas-Hinrich Lammers, Young Yang, Sang-Hyeon Lee, Yong-Man Kim, Eric J. Nestler, and M. Maral Mouradian

Dopamine receptor regulating factor, DRRF: A zinc finger transcription factor
PNAS 2001 98: 7558-7563; published online before print June 5, 2001, 10.1073/pnas.121635798 [Abstract] [Full Text] [PDF]  

Andreas W. Sailer, Hideki Sano, Zhizhen Zeng, Terrence P. McDonald, Jie Pan, Sheng-Shung Pong, Scott D. Feighner, Carina P. Tan, Takehiro Fukami, Hisashi Iwaasa, Donna L. Hreniuk, Nancy R. Morin, Sharon J. Sadowski, Makoto Ito, Masahiko Ito, Alka Bansal, Betty Ky, David J. Figueroa, Qingping Jiang, Christopher P. Austin, Douglas J. MacNeil, Akane Ishihara, Masaki Ihara, Akio Kanatani, Lex H. T. Van der Ploeg, Andrew D. Howard, and Qingyun Liu

Identification and characterization of a second melanin-concentrating hormone receptor, MCH-2R
PNAS 2001 98: 7564-7569; published online before print June 12, 2001, 10.1073/pnas.121170598 [Abstract] [Full Text] [PDF]  

K. Lewis, C. Li, M. H. Perrin, A. Blount, K. Kunitake, C. Donaldson, J. Vaughan, T. M. Reyes, J. Gulyas, W. Fischer, L. Bilezikjian, J. Rivier, P. E. Sawchenko, and W. W. Vale

Identification of urocortin III, an additional member of the corticotropin-releasing factor (CRF) family with high affinity for the CRF2 receptor
PNAS 2001 98: 7570-7575. [Abstract] [Full Text] [PDF]  

Songzhu An, Gene Cutler, Jack Jiagang Zhao, Shu-Gui Huang, Hui Tian, Wanbo Li, Lingming Liang, Miki Rich, Amy Bakleh, Juan Du, Jin-Long Chen, and Kang Dai

Identification and characterization of a melanin-concentrating hormone receptor
PNAS 2001 98: 7576-7581. [Abstract] [Full Text] [PDF]  

Stéphanie Millecamps, Delphine Nicolle, Irène Ceballos-Picot, Jacques Mallet, and Martine Barkats

Synaptic sprouting increases the uptake capacities of motoneurons in amyotrophic lateral sclerosis mice
PNAS 2001 98: 7582-7587; published online before print June 12, 2001, 10.1073/pnas.131031098 [Abstract] [Full Text] [PDF]  

Gregory F. Lopreato, Ying Lu, Amber Southwell, Nigel S. Atkinson, David M. Hillis, Thomas P. Wilcox, and Harold H. Zakon

Evolution and divergence of sodium channel genes in vertebrates
PNAS 2001 98: 7588-7592. [Abstract] [Full Text] [PDF]  

Yasuaki Nakao, Yoshiaki Itoh, Tang-Yong Kuang, Michelle Cook, Jane Jehle, and Louis Sokoloff

Effects of anesthesia on functional activation of cerebral blood flow and metabolism
PNAS 2001 98: 7593-7598; published online before print June 5, 2001, 10.1073/pnas.121179898 [Abstract] [Full Text] [PDF]  

Pharmacology

W. I. Li, F. W. Berman, T. Okino, F. Yokokawa, T. Shioiri, W. H. Gerwick, and T. F. Murray

Antillatoxin is a marine cyanobacterial toxin that potently activates voltage-gated sodium channels
PNAS 2001 98: 7599-7604. [Abstract] [Full Text] [PDF]  

Karen T. Y. Shaw, Tadanobu Utsuki, Jack Rogers, Qian-Sheng Yu, Kumar Sambamurti, Arnold Brossi, Yuan-Wen Ge, Debomoy K. Lahiri, and Nigel H. Greig

Phenserine regulates translation of -amyloid precursor protein mRNA by a putative interleukin-1 responsive element, a target for drug development
PNAS 2001 98: 7605-7610; published online before print June 12, 2001, 10.1073/pnas.131152998 [Abstract] [Full Text] [PDF]  

Alexander Huber, Vivianne Padrun, Nicole Déglon, Patrick Aebischer, Hanns Möhler, and Detlev Boison

Grafts of adenosine-releasing cells suppress seizures in kindling epilepsy
PNAS 2001 98: 7611-7616; published online before print June 12, 2001, 10.1073/pnas.131102898 [Abstract] [Full Text] [PDF]  

Kazuaki Yoshioka, Osamu Saitoh, and Hiroyasu Nakata

Heteromeric association creates a P2Y-like adenosine receptor
PNAS 2001 98: 7617-7622; published online before print June 5, 2001, 10.1073/pnas.121587098 [Abstract] [Full Text] [PDF]  

Physiology

Antonio J. Carrasco, Petras P. Dzeja, Alexey E. Alekseev, Darko Pucar, Leonid V. Zingman, M. Roselle Abraham, Denice Hodgson, Martin Bienengraeber, Michel Puceat, Edwin Janssen, Be Wieringa, and Andre Terzic

Adenylate kinase phosphotransfer communicates cellular energetic signals to ATP-sensitive potassium channels
PNAS 2001 98: 7623-7628; published online before print June 5, 2001, 10.1073/pnas.121038198 [Abstract] [Full Text] [PDF]  

Gitta Neufang, Gerhard Fürstenberger, Markus Heidt, Friedrich Marks, and Karin Müller-Decker

Abnormal differentiation of epidermis in transgenic mice constitutively expressing cyclooxygenase-2 in skin
PNAS 2001 98: 7629-7634; published online before print May 29, 2001, 10.1073/pnas.121574098 [Abstract] [Full Text] [PDF]  

Plant Biology

Silvana Petruccelli, Shunhong Dai, Rosa Carcamo, Yanhai Yin, Shouyi Chen, and Roger N. Beachy

Transcription factor RF2a alters expression of the rice tungro bacilliform virus promoter in transgenic tobacco plants
PNAS 2001 98: 7635-7640; published online before print June 5, 2001, 10.1073/pnas.121186398 [Abstract] [Full Text] [PDF]  

CORRECTIONS

Correction for vol. 98, p. 200 [Full Text] [PDF]  

Correction for vol. 93, p. 12406 [Full Text] [PDF]  

Correction for vol. 98, p. 5146 [Full Text] [PDF]  

Correction for vol. 98, p. 6402 [Full Text] [PDF]  

Correction for vol. 96, p. 8567 [Full Text] [PDF]  

Correction for vol. 98, p. 5288 [Full Text] [PDF]