COMMENTARIES

David Tilman

An evolutionary approach to ecosystem functioning
PNAS 2001 98: 10979-10980. [Full Text] [PDF]  

Robert E. Cleland

Unlocking the mysteries of leaf primordia formation
PNAS 2001 98: 10981-10982. [Full Text] [PDF]  

Joseph R. Testa and Alfonso Bellacosa

AKT plays a central role in tumorigenesis
PNAS 2001 98: 10983-10985. [Full Text] [PDF]  

Carlo M. Croce

How can we prevent cancer?
PNAS 2001 98: 10986-10988. [Full Text] [PDF]  

James McCulloch and Deborah Dewar

A radical approach to stroke therapy
PNAS 2001 98: 10989-10991. [Full Text] [PDF]  

David L. Chopp

Replacing iterative algorithms with single-pass algorithms
PNAS 2001 98: 10992-10993. [Full Text] [PDF]  

COLLOQUIUM:
Neural Signaling

Solomon H. Snyder

Arthur M. Sackler and science
PNAS 2001 98: 10994-10995. [Full Text] [PDF]  

David E. Barañano and Solomon H. Snyder

Neural roles for heme oxygenase: Contrasts to nitric oxide synthase
PNAS 2001 98: 10996-11002. [Abstract] [Full Text] [PDF]  

Dietmar Schmitz, Jack Mellor, Matthew Frerking, and Roger A. Nicoll

Presynaptic kainate receptors at hippocampal mossy fiber synapses
PNAS 2001 98: 11003-11008. [Abstract] [Full Text] [PDF]  

Huizhong W. Tao and Mu-ming Poo

Retrograde signaling at central synapses
PNAS 2001 98: 11009-11015. [Abstract] [Full Text] [PDF]  

B. Alexander Yi, Daniel L. Minor Jr., Yu-Fung Lin, Yuh Nung Jan, and Lily Yeh Jan

Controlling potassium channel activities: Interplay between the membrane and intracellular factors
PNAS 2001 98: 11016-11023. [Abstract] [Full Text] [PDF]  

Anne E. West, Wen G. Chen, Matthew B. Dalva, Ricardo E. Dolmetsch, Jon M. Kornhauser, Adam J. Shaywitz, Mari A. Takasu, Xu Tao, and Michael E. Greenberg

Calcium regulation of neuronal gene expression
PNAS 2001 98: 11024-11031. [Abstract] [Full Text] [PDF]  

Erin L. Peckol, Emily R. Troemel, and Cornelia I. Bargmann

Sensory experience and sensory activity regulate chemosensory receptor gene expression in Caenorhabditis elegans
PNAS 2001 98: 11032-11038. [Abstract] [Full Text] [PDF]  

Dennis J. Selkoe

Presenilin, Notch, and the genesis and treatment of Alzheimer's disease
PNAS 2001 98: 11039-11041. [Abstract] [Full Text] [PDF]  

Eric J. Nestler, Michel Barrot, and David W. Self

FosB: A sustained molecular switch for addiction
PNAS 2001 98: 11042-11046. [Abstract] [Full Text] [PDF]  

Raul R. Gainetdinov, Amy R. Mohn, Laura M. Bohn, and Marc G. Caron

Glutamatergic modulation of hyperactivity in mice lacking the dopamine transporter
PNAS 2001 98: 11047-11054. [Abstract] [Full Text] [PDF]  

Pat Manzerra, M. Margarita Behrens, Lorella M. T. Canzoniero, Xue Qing Wang, Valérie Heidinger, Tomomi Ichinose, Shan Ping Yu, and Dennis W. Choi

Zinc induces a Src family kinase-mediated up-regulation of NMDA receptor activity and excitotoxicity
PNAS 2001 98: 11055-11061. [Abstract] [Full Text] [PDF]  

Feng Liu, Xiao-Hong Ma, Jernej Ule, James A. Bibb, Akinori Nishi, Anthony J. DeMaggio, Zhen Yan, Angus C. Nairn, and Paul Greengard

Regulation of cyclin-dependent kinase 5 and casein kinase 1 by metabotropic glutamate receptors
PNAS 2001 98: 11062-11068. [Abstract] [Full Text] [PDF]  

PHYSICAL SCIENCES
Applied Mathematics

J. A. Sethian and A. Vladimirsky From the Cover: Ordered upwind methods for static Hamilton-Jacobi equations PNAS 2001 98: 11069-11074. [Abstract] [Full Text] [PDF]

Chemistry

Scott E. Schaus, Duccio Cavalieri, and Andrew G. Myers

Gene transcription analysis of Saccharomyces cerevisiae exposed to neocarzinostatin protein- chromophore complex reveals evidence of DNA damage, a potential mechanism of resistance, and consequences of prolonged exposure
PNAS 2001 98: 11075-11080; published online before print September 18, 2001, 10.1073/pnas.191340698 [Abstract] [Full Text] [PDF] [Supporting Information]  

J. M. G. Vilar and J. M. Rubí

Thermodynamics "beyond" local equilibrium
PNAS 2001 98: 11081-11084; published online before print September 18, 2001, 10.1073/pnas.191360398 [Abstract] [Full Text] [PDF]  

Martin T. Zanni, Nien-Hui Ge, Yung Sam Kim, and Robin M. Hochstrasser

Two-dimensional IR spectroscopy can be designed to eliminate the diagonal peaks and expose only the crosspeaks needed for structure determination
PNAS 2001 98: 11265-11270; published online before print September 18, 2001, 10.1073/pnas.201412998 [Abstract] [Full Text] [PDF]  

Geology

David V. Burley and William R. Dickinson

Origin and significance of a founding settlement in Polynesia
PNAS 2001 98: 11829-11831; published online before print September 18, 2001, 10.1073/pnas.181335398 [Abstract] [Full Text] [PDF]  

Geophysics

D. F. Hollenbach and J. M. Herndon

Deep-Earth reactor: Nuclear fission, helium, and the geomagnetic field
PNAS 2001 98: 11085-11090; published online before print September 18, 2001, 10.1073/pnas.201393998 [Abstract] [Full Text] [PDF]  

Physics

Yayu Wang and N. P. Ong

Particle-hole symmetry in the antiferromagnetic state of the cuprates
PNAS 2001 98: 11091-11096; published online before print September 18, 2001, 10.1073/pnas.201228498 [Abstract] [Full Text] [PDF]  

L. Alison McInnes, Susan K. Service, Victor I. Reus, Glenn Barnes, Olga Charlat, Satya Jawahar, Steve Lewitzky, Qing Yang, Quyen Duong, Mitzi Spesny, Carmen Araya, Xinia Araya, Alvaro Gallegos, Luis Meza, Julio Molina, Rolando Ramirez, Roxana Mendez, Sandra Silva, Eduardo Fournier, Steven L. Batki, Carol A. Mathews, Thomas Neylan, Charles E. Glatt, Michael A. Escamilla, David Luo, Paresh Gajiwala, Terry Song, Stephen Crook, Jasmine B. Nguyen, Erin Roche, Joanne M. Meyer, Pedro Leon, Lodewijk A. Sandkuijl, Nelson B. Freimer, and Hong Chen

Fine-scale mapping of a locus for severe bipolar mood disorder on chromosome 18p11.3 in the Costa Rican population
PNAS 2001 98: 11485-11490. [Abstract] [Full Text] [PDF] [Supporting Table]  

SOCIAL SCIENCES
Anthropology

Serge Lebel, Erik Trinkaus, Martine Faure, Philippe Fernandez, Claude Guérin, Daniel Richter, Norbert Mercier, Helène Valladas, and Günther A. Wagner

Comparative morphology and paleobiology of Middle Pleistocene human remains from the Bau de l'Aubesier, Vaucluse, France
PNAS 2001 98: 11097-11102; published online before print September 11, 2001, 10.1073/pnas.181353998 [Abstract] [Full Text] [PDF]  

David V. Burley and William R. Dickinson

Origin and significance of a founding settlement in Polynesia
PNAS 2001 98: 11829-11831; published online before print September 18, 2001, 10.1073/pnas.181335398 [Abstract] [Full Text] [PDF]  

Economic Sciences

Kevin McCabe, Daniel Houser, Lee Ryan, Vernon Smith, and Theodore Trouard

A functional imaging study of cooperation in two-person reciprocal exchange
PNAS 2001 98: 11832-11835; published online before print September 18, 2001, 10.1073/pnas.211415698 [Abstract] [Full Text] [PDF]  

BIOLOGICAL SCIENCES
Anthropology

Serge Lebel, Erik Trinkaus, Martine Faure, Philippe Fernandez, Claude Guérin, Daniel Richter, Norbert Mercier, Helène Valladas, and Günther A. Wagner

Comparative morphology and paleobiology of Middle Pleistocene human remains from the Bau de l'Aubesier, Vaucluse, France
PNAS 2001 98: 11097-11102; published online before print September 11, 2001, 10.1073/pnas.181353998 [Abstract] [Full Text] [PDF]  

Applied Biological Sciences

Won Seon Choi, G. G. Krishna Murthy, David A. Edwards, Robert Langer, and Alexander M. Klibanov

Inhalation delivery of proteins from ethanol suspensions
PNAS 2001 98: 11103-11107; published online before print September 18, 2001, 10.1073/pnas.201413798 [Abstract] [Full Text] [PDF]  

Biochemistry

Richard J. Bennett and James C. Wang

Association of yeast DNA topoisomerase III and Sgs1 DNA helicase: Studies of fusion proteins
PNAS 2001 98: 11108-11113; published online before print September 11, 2001, 10.1073/pnas.201387098 [Abstract] [Full Text] [PDF]  

Leon Chen, Harvey Hahn, Guangyu Wu, Che-Hong Chen, Tamar Liron, Deborah Schechtman, Gabriele Cavallaro, Lucia Banci, Yiru Guo, Roberto Bolli, Gerald W. Dorn II, and Daria Mochly-Rosen

Opposing cardioprotective actions and parallel hypertrophic effects of PKC and PKC
PNAS 2001 98: 11114-11119; published online before print September 11, 2001, 10.1073/pnas.191369098 [Abstract] [Full Text] [PDF]  

Jason S. Feinberg and Simpson Joseph

Identification of molecular interactions between P-site tRNA and the ribosome essential for translocation
PNAS 2001 98: 11120-11125; published online before print September 18, 2001, 10.1073/pnas.211184098 [Abstract] [Full Text] [PDF]  

Erman Munir, Jeong Jun Yoon, Toshiaki Tokimatsu, Takefumi Hattori, and Mikio Shimada

A physiological role for oxalic acid biosynthesis in the wood-rotting basidiomycete Fomitopsis palustris
PNAS 2001 98: 11126-11130; published online before print September 11, 2001, 10.1073/pnas.191389598 [Abstract] [Full Text] [PDF]  

Miljan Simonovic, Peter G. W. Gettins, and Karl Volz

Crystal structure of human PEDF, a potent anti-angiogenic and neurite growth-promoting factor
PNAS 2001 98: 11131-11135; published online before print September 18, 2001, 10.1073/pnas.211268598 [Abstract] [Full Text] [PDF]  

Nikolaos Gaitatzis, Brigitte Kunze, and Rolf Müller

In vitro reconstitution of the myxochelin biosynthetic machinery of Stigmatella aurantiaca Sg a15: Biochemical characterization of a reductive release mechanism from nonribosomal peptide synthetases
PNAS 2001 98: 11136-11141; published online before print September 18, 2001, 10.1073/pnas.201167098 [Abstract] [Full Text] [PDF]  

Klaus Eckart, Olaf Jahn, Jelena Radulovic, Hossein Tezval, Lars van Werven, and Joachim Spiess

A single amino acid serves as an affinity switch between the receptor and the binding protein of corticotropin-releasing factor: Implications for the design of agonists and antagonists
PNAS 2001 98: 11142-11147. [Abstract] [Full Text] [PDF]  

Steven H. D. Haddock, Trevor J. Rivers, and Bruce H. Robison

Can coelenterates make coelenterazine? Dietary requirement for luciferin in cnidarian bioluminescence
PNAS 2001 98: 11148-11151. [Abstract] [Full Text] [PDF]  

Fujihiko Matsunaga, Patrick Forterre, Yoshizumi Ishino, and Hannu Myllykallio

In vivo interactions of archaeal Cdc6/Orc1 and minichromosome maintenance proteins with the replication origin
PNAS 2001 98: 11152-11157; published online before print September 18, 2001, 10.1073/pnas.191387498 [Abstract] [Full Text] [PDF] [Supporting Figure]  

Junhui Sun, Chunlin Xin, Jerry P. Eu, Jonathan S. Stamler, and Gerhard Meissner

Cysteine-3635 is responsible for skeletal muscle ryanodine receptor modulation by NO
PNAS 2001 98: 11158-11162; published online before print September 18, 2001, 10.1073/pnas.201289098 [Abstract] [Full Text] [PDF]  

Hangil Park, Tadashi Suzuki, and William J. Lennarz

Identification of proteins that interact with mammalian peptide:N-glycanase and implicate this hydrolase in the proteasome-dependent pathway for protein degradation
PNAS 2001 98: 11163-11168; published online before print September 18, 2001, 10.1073/pnas.201393498 [Abstract] [Full Text] [PDF]  

Mark T. Hilgers and Martha L. Ludwig

Crystal structure of the quorum-sensing protein LuxS reveals a catalytic metal site
PNAS 2001 98: 11169-11174; published online before print September 11, 2001, 10.1073/pnas.191223098 [Abstract] [Full Text] [PDF]  

Junichi Takagi, Natalia Beglova, Padmaja Yalamanchili, Stephen C. Blacklow, and Timothy A. Springer

Definition of EGF-like, closely interacting modules that bear activation epitopes in integrin subunits
PNAS 2001 98: 11175-11180. [Abstract] [Full Text] [PDF]  

Ya Ha, David J. Stevens, John J. Skehel, and Don C. Wiley

X-ray structures of H5 avian and H9 swine influenza virus hemagglutinins bound to avian and human receptor analogs
PNAS 2001 98: 11181-11186; published online before print September 18, 2001, 10.1073/pnas.201401198 [Abstract] [Full Text] [PDF] [Supporting Figure]  

Debra M. Eckert and Peter S. Kim

Design of potent inhibitors of HIV-1 entry from the gp41 N-peptide region
PNAS 2001 98: 11187-11192. [Abstract] [Full Text] [PDF]  

Lee P. Lim and Christopher B. Burge

A computational analysis of sequence features involved in recognition of short introns
PNAS 2001 98: 11193-11198. [Abstract] [Full Text] [PDF] [Supporting Information]  

Alexandra Kikonyogo, Fadila Bouamr, Marcy L. Vana, Yan Xiang, Ashok Aiyar, Carol Carter, and Jonathan Leis

Proteins related to the Nedd4 family of ubiquitin protein ligases interact with the L domain of Rous sarcoma virus and are required for gag budding from cells
PNAS 2001 98: 11199-11204; published online before print September 18, 2001, 10.1073/pnas.201268998 [Abstract] [Full Text] [PDF] [Supporting Information]  

John H. Olson, Xueyu Xiang, Tillmann Ziegert, Andrew Kittelson, Alan Rawls, Allan L. Bieber, and Douglas E. Chandler

Allurin, a 21-kDa sperm chemoattractant from Xenopus egg jelly, is related to mammalian sperm-binding proteins
PNAS 2001 98: 11205-11210; published online before print September 18, 2001, 10.1073/pnas.211316798 [Abstract] [Full Text] [PDF]  

Michael Weinreich, Chun Liang, Hsu-Hsin Chen, and Bruce Stillman INAUGURAL ARTICLE by a Recently Elected Academy Member: Inaugural Article: Binding of cyclin-dependent kinases to ORC and Cdc6p regulates the chromosome replication cycle PNAS 2001 98: 11211-11217. [Abstract] [Full Text] [PDF]

Mischa Machius, Jacinta L. Chuang, R. Max Wynn, Diana R. Tomchick, and David T. Chuang From the Cover: Structure of rat BCKD kinase: Nucleotide-induced domain communication in a mitochondrial protein kinase PNAS 2001 98: 11218-11223; published online before print September 18, 2001, 10.1073/pnas.201220098 [Abstract] [Full Text] [PDF]

Ken Motohashi, Aiko Kondoh, Michael T. Stumpp, and Toru Hisabori

Comprehensive survey of proteins targeted by chloroplast thioredoxin
PNAS 2001 98: 11224-11229; published online before print September 11, 2001, 10.1073/pnas.191282098 [Abstract] [Full Text] [PDF]  

Sergio D. Catz, Jennifer L. Johnson, and Bernard M. Babior

Characterization of the nucleotide-binding capacity and the ATPase activity of the PIP₃-binding protein JFC1
PNAS 2001 98: 11230-11235; published online before print September 11, 2001, 10.1073/pnas.191369598 [Abstract] [Full Text] [PDF]  

Laura A. Lindsey-Boltz, Vladimir P. Bermudez, Jerard Hurwitz, and Aziz Sancar

Purification and characterization of human DNA damage checkpoint Rad complexes
PNAS 2001 98: 11236-11241. [Abstract] [Full Text] [PDF]  

M. M. Teeter, A. Yamano, B. Stec, and U. Mohanty

On the nature of a glassy state of matter in a hydrated protein: Relation to protein function
PNAS 2001 98: 11242-11247. [Abstract] [Full Text] [PDF] [Supporting Text]  

Stefan Lutz, Marc Ostermeier, Gregory L. Moore, Costas D. Maranas, and Stephen J. Benkovic

Creating multiple-crossover DNA libraries independent of sequence identity
PNAS 2001 98: 11248-11253; published online before print September 18, 2001, 10.1073/pnas.201413698 [Abstract] [Full Text] [PDF] [Supporting Information]  

Biophysics

Sander Woutersen, Yuguang Mu, Gerhard Stock, and Peter Hamm

Subpicosecond conformational dynamics of small peptides probed by two-dimensional vibrational spectroscopy
PNAS 2001 98: 11254-11258; published online before print September 11, 2001, 10.1073/pnas.201169498 [Abstract] [Full Text] [PDF]  

P. D. Twigg, G. Parthasarathy, L. Guerrero, T. M. Logan, and D. L. D. Caspar

Disordered to ordered folding in the regulation of diphtheria toxin repressor activity
PNAS 2001 98: 11259-11264. [Abstract] [Full Text] [PDF] [Supporting Information]  

Martin T. Zanni, Nien-Hui Ge, Yung Sam Kim, and Robin M. Hochstrasser

Two-dimensional IR spectroscopy can be designed to eliminate the diagonal peaks and expose only the crosspeaks needed for structure determination
PNAS 2001 98: 11265-11270; published online before print September 18, 2001, 10.1073/pnas.201412998 [Abstract] [Full Text] [PDF]  

Dennis H. Oh, Brett A. King, Steven G. Boxer, and Philip C. Hanawalt

Spatially localized generation of nucleotide sequence-specific DNA damage
PNAS 2001 98: 11271-11276. [Abstract] [Full Text] [PDF]  

Jun Chen, John S. Mitcheson, Martin Tristani-Firouzi, Monica Lin, and Michael C. Sanguinetti

The S4-S5 linker couples voltage sensing and activation of pacemaker channels
PNAS 2001 98: 11277-11282; published online before print September 11, 2001, 10.1073/pnas.201250598 [Abstract] [Full Text] [PDF]  

Cell Biology

Peter Duesberg, Reinhard Stindl, and Ruediger Hehlmann

Origin of multidrug resistance in cells with and without multidrug resistance genes: Chromosome reassortments catalyzed by aneuploidy
PNAS 2001 98: 11283-11288; published online before print September 11, 2001, 10.1073/pnas.201398998 [Abstract] [Full Text] [PDF]  

Antonia Lopez-Girona, Katsunori Tanaka, Xiao-Bo Chen, Beth A. Baber, Clare H. McGowan, and Paul Russell

Serine-345 is required for Rad3-dependent phosphorylation and function of checkpoint kinase Chk1 in fission yeast
PNAS 2001 98: 11289-11294; published online before print September 11, 2001, 10.1073/pnas.191557598 [Abstract] [Full Text] [PDF]  

Hong-Bei Wang, Micah Dembo, Steven K. Hanks, and Yu-li Wang

Focal adhesion kinase is involved in mechanosensing during fibroblast migration
PNAS 2001 98: 11295-11300. [Abstract] [Full Text] [PDF]  

Wenbo Xu, M. H. Jericho, I. A. Meinertzhagen, and H. J. Kreuzer

Digital in-line holography for biological applications
PNAS 2001 98: 11301-11305. [Abstract] [Full Text] [PDF]  

Hsin-Yi Henry Ho, Rajat Rohatgi, Le Ma, and Marc W. Kirschner

CR16 forms a complex with N-WASP in brain and is a novel member of a conserved proline-rich actin-binding protein family
PNAS 2001 98: 11306-11311; published online before print September 11, 2001, 10.1073/pnas.211420498 [Abstract] [Full Text] [PDF]  

Christian Endter, Julia Kzhyshkowska, Roland Stauber, and Thomas Dobner

SUMO-1 modification required for transformation by adenovirus type 5 early region 1B 55-kDa oncoprotein
PNAS 2001 98: 11312-11317; published online before print September 11, 2001, 10.1073/pnas.191361798 [Abstract] [Full Text] [PDF]  

Jia-wen Han, Cathy Flemington, Anne B. Houghton, Zhengming Gu, Gerard P. Zambetti, Robert J. Lutz, Li Zhu, and Thomas Chittenden

Expression of bbc3, a pro-apoptotic BH3-only gene, is regulated by diverse cell death and survival signals
PNAS 2001 98: 11318-11323. [Abstract] [Full Text] [PDF]  

Ivan V. Maly and Gary G. Borisy

Self-organization of a propulsive actin network as an evolutionary process
PNAS 2001 98: 11324-11329. [Abstract] [Full Text] [PDF]  

Frank Stümpel, Rémy Burcelin, Kurt Jungermann, and Bernard Thorens

Normal kinetics of intestinal glucose absorption in the absence of GLUT2: Evidence for a transport pathway requiring glucose phosphorylation and transfer into the endoplasmic reticulum
PNAS 2001 98: 11330-11335; published online before print September 18, 2001, 10.1073/pnas.211357698 [Abstract] [Full Text] [PDF]  

Yan Zhang, Hua Wang, Shigeaki Toratani, J. Denry Sato, Mikio Kan, Wallace L. McKeehan, and Tetsuji Okamoto

Growth inhibition by keratinocyte growth factor receptor of human salivary adenocarcinoma cells through induction of differentiation and apoptosis
PNAS 2001 98: 11336-11340; published online before print September 18, 2001, 10.1073/pnas.191377098 [Abstract] [Full Text] [PDF]  

Developmental Biology

Cassandra Extavour and Antonio García-Bellido

Germ cell selection in genetic mosaics in Drosophila melanogaster
PNAS 2001 98: 11341-11346. [Abstract] [Full Text] [PDF]  

Catherine S. Lee, Laura Buttitta, and Chen-Ming Fan

Evidence that the WNT-inducible growth arrest-specific gene 1 encodes an antagonist of sonic hedgehog signaling in the somite
PNAS 2001 98: 11347-11352. [Abstract] [Full Text] [PDF]  

Jose Marcelino, Christopher M. Sciortino, Michael F. Romero, Lynn M. Ulatowski, R. Tracy Ballock, Aris N. Economides, Peter M. Eimon, Richard M. Harland, and Matthew L. Warman

Human disease-causing NOG missense mutations: Effects on noggin secretion, dimer formation, and bone morphogenetic protein binding
PNAS 2001 98: 11353-11358; published online before print September 18, 2001, 10.1073/pnas.201367598 [Abstract] [Full Text] [PDF]  

Daniel Chagnovich and Ruth Lehmann

Poly(A)-independent regulation of maternal hunchback translation in the Drosophila embryo
PNAS 2001 98: 11359-11364; published online before print September 18, 2001, 10.1073/pnas.201284398 [Abstract] [Full Text] [PDF] [Supporting Information]  

Ecology

Jeremy T. Kerr, T. R. E. Southwood, and Josef Cihlar

Remotely sensed habitat diversity predicts butterfly species richness and community similarity in Canada
PNAS 2001 98: 11365-11370; published online before print September 11, 2001, 10.1073/pnas.201398398 [Abstract] [Full Text] [PDF]  

J. E. Yack, M. L. Smith, and P. J. Weatherhead

Caterpillar talk: Acoustically mediated territoriality in larval Lepidoptera
PNAS 2001 98: 11371-11375; published online before print September 18, 2001, 10.1073/pnas.191378898 [Abstract] [Full Text] [PDF] [Supporting Movies]  

Jon Norberg, Dennis P. Swaney, Jonathan Dushoff, Juan Lin, Renato Casagrandi, and Simon A. Levin

Phenotypic diversity and ecosystem functioning in changing environments: A theoretical framework
PNAS 2001 98: 11376-11381; published online before print September 4, 2001, 10.1073/pnas.171315998 [Abstract] [Full Text] [PDF]  

Evolution

Byrappa Venkatesh, Mark V. Erdmann, and Sydney Brenner

Molecular synapomorphies resolve evolutionary relationships of extant jawed vertebrates
PNAS 2001 98: 11382-11387; published online before print September 11, 2001, 10.1073/pnas.201415598 [Abstract] [Full Text] [PDF]  

Susanna K. Remold and Richard E. Lenski

Contribution of individual random mutations to genotype-by-environment interactions in Escherichia coli
PNAS 2001 98: 11388-11393. [Abstract] [Full Text] [PDF]  

Rebecca M. Kilner

A growth cost of begging in captive canary chicks
PNAS 2001 98: 11394-11398. [Abstract] [Full Text] [PDF]  

Toshiyuki Hayakawa, Yoko Satta, Pascal Gagneux, Ajit Varki, and Naoyuki Takahata

Alu-mediated inactivation of the human CMP- N-acetylneuraminic acid hydroxylase gene
PNAS 2001 98: 11399-11404; published online before print September 18, 2001, 10.1073/pnas.191268198 [Abstract] [Full Text] [PDF]  

Francisco Rodríguez-Trelles, Rosa Tarrío, and Francisco J. Ayala

Erratic overdispersion of three molecular clocks: GPDH, SOD, and XDH
PNAS 2001 98: 11405-11410; published online before print September 11, 2001, 10.1073/pnas.201392198 [Abstract] [Full Text] [PDF]  

Emma Hambly, Francoise Tétart, Carine Desplats, William H. Wilson, Henry M. Krisch, and Nicholas H. Mann

A conserved genetic module that encodes the major virion components in both the coliphage T4 and the marine cyanophage S-PM2
PNAS 2001 98: 11411-11416; published online before print September 11, 2001, 10.1073/pnas.191174498 [Abstract] [Full Text] [PDF]  

Genetics

Scott E. Schaus, Duccio Cavalieri, and Andrew G. Myers

Gene transcription analysis of Saccharomyces cerevisiae exposed to neocarzinostatin protein- chromophore complex reveals evidence of DNA damage, a potential mechanism of resistance, and consequences of prolonged exposure
PNAS 2001 98: 11075-11080; published online before print September 18, 2001, 10.1073/pnas.191340698 [Abstract] [Full Text] [PDF] [Supporting Information]  

Adam J. W. Paige, Karen J. Taylor, Claire Taylor, Stephen G. Hillier, Susan Farrington, Diane Scott, David J. Porteous, John F. Smyth, Hani Gabra, and J. E. Vivienne Watson

WWOX: A candidate tumor suppressor gene involved in multiple tumor types
PNAS 2001 98: 11417-11422. [Abstract] [Full Text] [PDF] [Supporting Table]  

Kyu-Kye Hwang, Joel C. Eissenberg, and Howard J. Worman

Transcriptional repression of euchromatic genes by Drosophila heterochromatin protein 1 and histone modifiers
PNAS 2001 98: 11423-11427; published online before print September 18, 2001, 10.1073/pnas.211303598 [Abstract] [Full Text] [PDF]  

Ilaria Taddei, Masae Morishima, Tuong Huynh, and Elizabeth A. Lindsay

Genetic factors are major determinants of phenotypic variability in a mouse model of the DiGeorge/del22q11 syndromes
PNAS 2001 98: 11428-11431; published online before print September 18, 2001, 10.1073/pnas.201127298 [Abstract] [Full Text] [PDF]  

Dirk Schübeler, Mark Groudine, and M. A. Bender

The murine -globin locus control region regulates the rate of transcription but not the hyperacetylation of histones at the active genes
PNAS 2001 98: 11432-11437; published online before print September 11, 2001, 10.1073/pnas.201394698 [Abstract] [Full Text] [PDF] [Supporting Table]  

Daichang Yang, Liying Wu, Yong-Sic Hwang, Lifang Chen, and Ning Huang

Expression of the REB transcriptional activator in rice grains improves the yield of recombinant proteins whose genes are controlled by a Reb-responsive promoter
PNAS 2001 98: 11438-11443. [Abstract] [Full Text] [PDF]  

Roberto A. Gaxiola, Jisheng Li, Soledad Undurraga, Lien M. Dang, Gethyn J. Allen, Seth L. Alper, and Gerald R. Fink

Drought- and salt-tolerant plants result from overexpression of the AVP1 H⁺-pump
PNAS 2001 98: 11444-11449. [Abstract] [Full Text] [PDF]  

Alexander Pfeifer, Eugene P. Brandon, Neeltje Kootstra, Fred H. Gage, and Inder M. Verma

Delivery of the Cre recombinase by a self-deleting lentiviral vector: Efficient gene targeting in vivo
PNAS 2001 98: 11450-11455; published online before print September 11, 2001, 10.1073/pnas.201415498 [Abstract] [Full Text] [PDF]  

Teruhisa Tsuzuki, Akinori Egashira, Hisato Igarashi, Tomoo Iwakuma, Yoko Nakatsuru, Yohei Tominaga, Hisaya Kawate, Kazuki Nakao, Kenji Nakamura, Fumio Ide, Shinobu Kura, Yusaku Nakabeppu, Motoya Katsuki, Takatoshi Ishikawa, and Mutsuo Sekiguchi

Spontaneous tumorigenesis in mice defective in the MTH1 gene encoding 8-oxo-dGTPase
PNAS 2001 98: 11456-11461. [Abstract] [Full Text] [PDF]  

Mike West, Carrie Blanchette, Holly Dressman, Erich Huang, Seiichi Ishida, Rainer Spang, Harry Zuzan, John A. Olson Jr., Jeffrey R. Marks, and Joseph R. Nevins

Predicting the clinical status of human breast cancer by using gene expression profiles
PNAS 2001 98: 11462-11467; published online before print September 18, 2001, 10.1073/pnas.201162998 [Abstract] [Full Text] [PDF] [Supporting Information]  

Xinhe Wang, Elizabeth Quail, Nai-Jung Hung, Yongjun Tan, Honggang Ye, and Robert H. Costa

Increased levels of forkhead box M1B transcription factor in transgenic mouse hepatocytes prevent age-related proliferation defects in regenerating liver
PNAS 2001 98: 11468-11473. [Abstract] [Full Text] [PDF]  

Laskaro Zagoraiou, Dubravka Drabek, Sofia Alexaki, Jacky A. Guy, Apostolos G. Klinakis, An Langeveld, George Skavdis, Clio Mamalaki, Frank Grosveld, and Charalambos Savakis

In vivo transposition of Minos, a Drosophila mobile element, in mammalian tissues
PNAS 2001 98: 11474-11478; published online before print September 18, 2001, 10.1073/pnas.201392398 [Abstract] [Full Text] [PDF]  

David L. Remington, Jeffry M. Thornsberry, Yoshihiro Matsuoka, Larissa M. Wilson, Sherry R. Whitt, John Doebley, Stephen Kresovich, Major M. Goodman, and Edward S. Buckler IV

Structure of linkage disequilibrium and phenotypic associations in the maize genome
PNAS 2001 98: 11479-11484; published online before print September 18, 2001, 10.1073/pnas.201394398 [Abstract] [Full Text] [PDF] [Supporting Tables]  

L. Alison McInnes, Susan K. Service, Victor I. Reus, Glenn Barnes, Olga Charlat, Satya Jawahar, Steve Lewitzky, Qing Yang, Quyen Duong, Mitzi Spesny, Carmen Araya, Xinia Araya, Alvaro Gallegos, Luis Meza, Julio Molina, Rolando Ramirez, Roxana Mendez, Sandra Silva, Eduardo Fournier, Steven L. Batki, Carol A. Mathews, Thomas Neylan, Charles E. Glatt, Michael A. Escamilla, David Luo, Paresh Gajiwala, Terry Song, Stephen Crook, Jasmine B. Nguyen, Erin Roche, Joanne M. Meyer, Pedro Leon, Lodewijk A. Sandkuijl, Nelson B. Freimer, and Hong Chen

Fine-scale mapping of a locus for severe bipolar mood disorder on chromosome 18p11.3 in the Costa Rican population
PNAS 2001 98: 11485-11490. [Abstract] [Full Text] [PDF] [Supporting Table]  

Immunology

Oscar Bruña-Romero, Gloria González-Aseguinolaza, Julius C. R. Hafalla, Moriya Tsuji, and Ruth S. Nussenzweig

Complete, long-lasting protection against malaria of mice primed and boosted with two distinct viral vectors expressing the same plasmodial antigen
PNAS 2001 98: 11491-11496; published online before print September 11, 2001, 10.1073/pnas.191380898 [Abstract] [Full Text] [PDF]  

Jan A. M. Langermans, Peter Andersen, Dick van Soolingen, Richard A. W. Vervenne, Patrice A. Frost, Tridia van der Laan, Laurens A. H. van Pinxteren, Jan van den Hombergh, Saskia Kroon, Inge Peekel, Sandrine Florquin, and Alan W. Thomas

Divergent effect of bacillus Calmette-Guérin (BCG) vaccination on Mycobacterium tuberculosis infection in highly related macaque species: Implications for primate models in tuberculosis vaccine research
PNAS 2001 98: 11497-11502; published online before print September 18, 2001, 10.1073/pnas.201404898 [Abstract] [Full Text] [PDF]  

Caroline Oberholzer, Andreas Oberholzer, Frances R. Bahjat, Rebecca M. Minter, Cynthia L. Tannahill, Amer Abouhamze, Drake LaFace, Beth Hutchins, Michael J. Clare-Salzler, and Lyle L. Moldawer

Targeted adenovirus-induced expression of IL-10 decreases thymic apoptosis and improves survival in murine sepsis
PNAS 2001 98: 11503-11508; published online before print September 11, 2001, 10.1073/pnas.181338198 [Abstract] [Full Text] [PDF]  

Zeno Földes-Papp, Ulrike Demel, and Gernot P. Tilz

Ultrasensitive detection and identification of fluorescent molecules by FCS: Impact for immunobiology
PNAS 2001 98: 11509-11514. [Abstract] [Full Text] [PDF]  

J. P. Medema, J. de Jong, L. T. C. Peltenburg, E. M. E. Verdegaal, A. Gorter, S. A. Bres, K. L. M. C. Franken, M. Hahne, J. P. Albar, C. J. M. Melief, and R. Offringa

Blockade of the granzyme B/perforin pathway through overexpression of the serine protease inhibitor PI-9/SPI-6 constitutes a mechanism for immune escape by tumors
PNAS 2001 98: 11515-11520; published online before print September 18, 2001, 10.1073/pnas.201398198 [Abstract] [Full Text] [PDF]  

Adelheid Cerwenka, Jody L. Baron, and Lewis L. Lanier

Ectopic expression of retinoic acid early inducible-1 gene (RAE-1) permits natural killer cell-mediated rejection of a MHC class I-bearing tumor in vivo
PNAS 2001 98: 11521-11526; published online before print September 18, 2001, 10.1073/pnas.201238598 [Abstract] [Full Text] [PDF]  

Liping Geng, Stefan Pfister, Stine-Kathrein Kraeft, and Christopher E. Rudd

Adaptor FYB (Fyn-binding protein) regulates integrin-mediated adhesion and mediator release: Differential involvement of the FYB SH3 domain
PNAS 2001 98: 11527-11532; published online before print September 11, 2001, 10.1073/pnas.191378198 [Abstract] [Full Text] [PDF]  

Emma E. Hamilton-Williams, David V. Serreze, Brett Charlton, Ellis A. Johnson, Michele P. Marron, Arno Müllbacher, and Robyn M. Slattery

Transgenic rescue implicates ₂-microglobulin as a diabetes susceptibility gene in nonobese diabetic (NOD) mice
PNAS 2001 98: 11533-11538. [Abstract] [Full Text] [PDF]  

Qingxian Kong, Liz Richter, Yu Fang Yang, Charles J. Arntzen, Hugh S. Mason, and Yasmin Thanavala

Oral immunization with hepatitis B surface antigen expressed in transgenic plants
PNAS 2001 98: 11539-11544; published online before print September 11, 2001, 10.1073/pnas.191617598 [Abstract] [Full Text] [PDF]  

Yu-quan Wei, Mei-juan Huang, Li Yang, Xia Zhao, Ling Tian, You Lu, Jing-mei Shu, Chong-jiu Lu, Ting Niu, Bin Kang, Yun-qiu Mao, Fen Liu, Yan-jun Wen, Shong Lei, Feng Luo, Li-qun Zhou, Feng Peng, Yu Jiang, Ji-yan Liu, Hao Zhou, Qing-ru Wang, Qiu-ming He, Fei Xiao, Yan-yan Lou, Xing-jiang Xie, Qiu Li, Yang Wu, Zhen-yu Ding, Bin Hu, Min Hu, and Wei Zhang

Immunogene therapy of tumors with vaccine based on Xenopus homologous vascular endothelial growth factor as a model antigen
PNAS 2001 98: 11545-11550; published online before print September 11, 2001, 10.1073/pnas.191112198 [Abstract] [Full Text] [PDF]  

Medical Sciences

Malgorzata Hanausek, Pattabhiraman Ganesh, Zbigniew Walaszek, Charles J. Arntzen, Thomas J. Slaga, and Jordan U. Gutterman From the Cover: Avicins, a family of triterpenoid saponins from Acacia victoriae (Bentham), suppress H-ras mutations and aneuploidy in a murine skin carcinogenesis model PNAS 2001 98: 11551-11556. [Abstract] [Full Text] [PDF]

Valsala Haridas, Charles J. Arntzen, and Jordan U. Gutterman

Avicins, a family of triterpenoid saponins from Acacia victoriae (Bentham), inhibit activation of nuclear factor-B by inhibiting both its nuclear localization and ability to bind DNA
PNAS 2001 98: 11557-11562. [Abstract] [Full Text] [PDF]  

Bernard Kwabi-Addo, Dipak Giri, Karen Schmidt, Katrina Podsypanina, Ramon Parsons, Norman Greenberg, and Michael Ittmann

Haploinsufficiency of the Pten tumor suppressor gene promotes prostate cancer progression
PNAS 2001 98: 11563-11568; published online before print September 11, 2001, 10.1073/pnas.201167798 [Abstract] [Full Text] [PDF]  

Shobu Namura, Koji Iihara, Shinya Takami, Izumi Nagata, Haruhiko Kikuchi, Koji Matsushita, Michael A. Moskowitz, Joseph V. Bonventre, and Alessandro Alessandrini

Intravenous administration of MEK inhibitor U0126 affords brain protection against forebrain ischemia and focal cerebral ischemia
PNAS 2001 98: 11569-11574; published online before print August 14, 2001, 10.1073/pnas.181213498 [Abstract] [Full Text] [PDF]  

Evgenia Paxinou, Marie Weisse, Qiping Chen, Jose M. Souza, Caryn Hertkorn, Mary Selak, Evgueni Daikhin, Marc Yudkoff, Grzegorz Sowa, William C. Sessa, and Harry Ischiropoulos

Dynamic regulation of metabolism and respiration by endogenously produced nitric oxide protects against oxidative stress
PNAS 2001 98: 11575-11580; published online before print September 18, 2001, 10.1073/pnas.201293198 [Abstract] [Full Text] [PDF]  

Roger N. Pearse, Emilia M. Sordillo, Shmuel Yaccoby, Brian R. Wong, Deng F. Liau, Neville Colman, Joseph Michaeli, Joshua Epstein, and Yongwon Choi

Multiple myeloma disrupts the TRANCE/ osteoprotegerin cytokine axis to trigger bone destruction and promote tumor progression
PNAS 2001 98: 11581-11586; published online before print September 18, 2001, 10.1073/pnas.201394498 [Abstract] [Full Text] [PDF]  

Robert L. Raffaï, Li-Ming Dong, Robert V. Farese Jr., and Karl H. Weisgraber

Introduction of human apolipoprotein E4 "domain interaction" into mouse apolipoprotein E
PNAS 2001 98: 11587-11591; published online before print September 11, 2001, 10.1073/pnas.201279298 [Abstract] [Full Text] [PDF]  

James M. Allan, Christopher P. Wild, Sara Rollinson, Eleanor V. Willett, Anthony V. Moorman, Gareth J. Dovey, Philippa L. Roddam, Eve Roman, Raymond A. Cartwright, and Gareth J. Morgan

Polymorphism in glutathione S-transferase P1 is associated with susceptibility to chemotherapy-induced leukemia
PNAS 2001 98: 11592-11597; published online before print September 11, 2001, 10.1073/pnas.191211198 [Abstract] [Full Text] [PDF]  

Lindsey D. Mayo and David B. Donner

A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus
PNAS 2001 98: 11598-11603; published online before print August 14, 2001, 10.1073/pnas.181181198 [Abstract] [Full Text] [PDF] [Supplemental Table]  

Pepe Karhumaa, Jukka Leinonen, Seppo Parkkila, Kari Kaunisto, Juha Tapanainen, and Hannu Rajaniemi

The identification of secreted carbonic anhydrase VI as a constitutive glycoprotein of human and rat milk
PNAS 2001 98: 11604-11608; published online before print September 11, 2001, 10.1073/pnas.121172598 [Abstract] [Full Text] [PDF]  

Tobias Allander, Suzanne U. Emerson, Ronald E. Engle, Robert H. Purcell, and Jens Bukh

A virus discovery method incorporating DNase treatment and its application to the identification of two bovine parvovirus species
PNAS 2001 98: 11609-11614; published online before print September 18, 2001, 10.1073/pnas.211424698 [Abstract] [Full Text] [PDF]  

Microbiology

Stéphanie Gon, Cécile Jourlin-Castelli, Laurence Théraulaz, and Vincent Méjean

An unsuspected autoregulatory pathway involving apocytochrome TorC and sensor TorS in Escherichia coli
PNAS 2001 98: 11615-11620; published online before print September 18, 2001, 10.1073/pnas.211330598 [Abstract] [Full Text] [PDF]  

Steven S. Branda, José Eduardo González-Pastor, Sigal Ben-Yehuda, Richard Losick, and Roberto Kolter

Fruiting body formation by Bacillus subtilis
PNAS 2001 98: 11621-11626. [Abstract] [Full Text] [PDF]  

Brian P. Dalrymple, Kritaya Kongsuwan, Gene Wijffels, Nicholas E. Dixon, and Philip A. Jennings

A universal protein-protein interaction motif in the eubacterial DNA replication and repair systems
PNAS 2001 98: 11627-11632. [Abstract] [Full Text] [PDF] [Supporting Tables]  

M. Worth Calfee, James P. Coleman, and Everett C. Pesci

Interference with Pseudomonas quinolone signal synthesis inhibits virulence factor expression by Pseudomonas aeruginosa
PNAS 2001 98: 11633-11637. [Abstract] [Full Text] [PDF]  

Kachiko Sekiya, Minako Ohishi, Tomoaki Ogino, Koichi Tamano, Chihiro Sasakawa, and Akio Abe

Supermolecular structure of the enteropathogenic Escherichia coli type III secretion system and its direct interaction with the EspA-sheath-like structure
PNAS 2001 98: 11638-11643; published online before print September 18, 2001, 10.1073/pnas.191378598 [Abstract] [Full Text] [PDF] [Supporting Information]  

Manuela Mengozzi, Meena Malipatlolla, Stephen C. De Rosa, Leonard A. Herzenberg, Leonore A. Herzenberg, and Mario Roederer

Naïve CD4 T cells inhibit CD28-costimulated R5 HIV replication in memory CD4 T cells
PNAS 2001 98: 11644-11649; published online before print September 18, 2001, 10.1073/pnas.211205098 [Abstract] [Full Text] [PDF] [Supporting Information]  

Neurobiology

Paul M. Thompson, Christine Vidal, Jay N. Giedd, Peter Gochman, Jonathan Blumenthal, Robert Nicolson, Arthur W. Toga, and Judith L. Rapoport From the Cover: Mapping adolescent brain change reveals dynamic wave of accelerated gray matter loss in very early-onset schizophrenia PNAS 2001 98: 11650-11655. [Abstract] [Full Text] [PDF]

Lucia M. Vaina, Jeffrey Solomon, Sanjida Chowdhury, Pawan Sinha, and John W. Belliveau

Functional neuroanatomy of biological motion perception in humans
PNAS 2001 98: 11656-11661; published online before print September 11, 2001, 10.1073/pnas.191374198 [Abstract] [Full Text] [PDF]  

Donald E. Mitchell, Guy Gingras, and Peter C. Kind

Initial recovery of vision after early monocular deprivation in kittens is faster when both eyes are open
PNAS 2001 98: 11662-11667. [Abstract] [Full Text] [PDF]  

Alessandro Quattrone, Alessia Pascale, Xavier Nogues, Weiqin Zhao, Pavel Gusev, Alessandra Pacini, and Daniel L. Alkon

Posttranscriptional regulation of gene expression in learning by the neuronal ELAV-like mRNA-stabilizing proteins
PNAS 2001 98: 11668-11673. [Abstract] [Full Text] [PDF]  

Akira Mizoguchi, Naomi Eguchi, Kazushi Kimura, Yoshimoto Kiyohara, Wei-Min Qu, Zhi-Li Huang, Takatoshi Mochizuki, Michael Lazarus, Takuya Kobayashi, Takeshi Kaneko, Shuh Narumiya, Yoshihiro Urade, and Osamu Hayaishi

Dominant localization of prostaglandin D receptors on arachnoid trabecular cells in mouse basal forebrain and their involvement in the regulation of non-rapid eye movement sleep
PNAS 2001 98: 11674-11679; published online before print September 18, 2001, 10.1073/pnas.201398898 [Abstract] [Full Text] [PDF]  

Thomas Voets, Tobias Moser, Per-Eric Lund, Robert H. Chow, Martin Geppert, Thomas C. Südhof, and Erwin Neher

Intracellular calcium dependence of large dense-core vesicle exocytosis in the absence of synaptotagmin I
PNAS 2001 98: 11680-11685; published online before print September 18, 2001, 10.1073/pnas.201398798 [Abstract] [Full Text] [PDF]  

David D. Laws, Hans-Marcus L. Bitter, Kai Liu, Haydn L. Ball, Kiyatoshi Kaneko, Holger Wille, Fred E. Cohen, Stanley B. Prusiner, Alexander Pines, and David E. Wemmer

Solid-state NMR studies of the secondary structure of a mutant prion protein fragment of 55 residues that induces neurodegeneration
PNAS 2001 98: 11686-11690; published online before print September 18, 2001, 10.1073/pnas.201404298 [Abstract] [Full Text] [PDF]  

Tristan Darland and John E. Dowling

Behavioral screening for cocaine sensitivity in mutagenized zebrafish
PNAS 2001 98: 11691-11696; published online before print September 11, 2001, 10.1073/pnas.191380698 [Abstract] [Full Text] [PDF]  

David S. Tuch, Van J. Wedeen, Anders M. Dale, John S. George, and John W. Belliveau

Conductivity tensor mapping of the human brain using diffusion tensor MRI
PNAS 2001 98: 11697-11701. [Abstract] [Full Text] [PDF]  

Robert Galambos and Gábor Juhász

How patterns of bleached rods and cones become visual perceptual experiences: A proposal
PNAS 2001 98: 11702-11707; published online before print September 18, 2001, 10.1073/pnas.201420798 [Abstract] [Full Text] [PDF]  

Carol L. Thompson, William S. Blaner, Russell N. Van Gelder, Katherine Lai, Loredana Quadro, Vittorio Colantuoni, Max E. Gottesman, and Aziz Sancar

Preservation of light signaling to the suprachiasmatic nucleus in vitamin A-deficient mice
PNAS 2001 98: 11708-11713; published online before print September 18, 2001, 10.1073/pnas.201301498 [Abstract] [Full Text] [PDF]  

D. L. Misner, S. Jacobs, Y. Shimizu, A. M. de Urquiza, L. Solomin, T. Perlmann, L. M. De Luca, C. F. Stevens, and R. M. Evans

Vitamin A deprivation results in reversible loss of hippocampal long-term synaptic plasticity
PNAS 2001 98: 11714-11719; published online before print September 11, 2001, 10.1073/pnas.191369798 [Abstract] [Full Text] [PDF]  

Judy Huang, David B. Agus, Christopher J. Winfree, Szilard Kiss, William J. Mack, Ryan A. McTaggart, Tanvir F. Choudhri, Louis J Kim, J Mocco, David J. Pinsky, William D. Fox, Robert J. Israel, Thomas A. Boyd, David W. Golde, and E. Sander Connolly Jr.

Dehydroascorbic acid, a blood-brain barrier transportable form of vitamin C, mediates potent cerebroprotection in experimental stroke
PNAS 2001 98: 11720-11724. [Abstract] [Full Text] [PDF]  

Chong-Hyun Kim, Hee Jung Chung, Hey-Kyoung Lee, and Richard L. Huganir

Interaction of the AMPA receptor subunit GluR2/3 with PDZ domains regulates hippocampal long-term depression
PNAS 2001 98: 11725-11730. [Abstract] [Full Text] [PDF]  

Yongsheng Shi, F. Bernhard Radlwimmer, and Shozo Yokoyama

Molecular genetics and the evolution of ultraviolet vision in vertebrates
PNAS 2001 98: 11731-11736. [Abstract] [Full Text] [PDF]  

Pharmacology

A. Gonçalves, D. Braguer, K. Kamath, L. Martello, C. Briand, S. Horwitz, L. Wilson, and M. A. Jordan

Resistance to Taxol in lung cancer cells associated with increased microtubule dynamics
PNAS 2001 98: 11737-11742; published online before print September 18, 2001, 10.1073/pnas.191388598 [Abstract] [Full Text] [PDF] [Supporting Movies]  

R. B. Lichtner, A. Rotgeri, T. Bunte, B. Buchmann, J. Hoffmann, W. Schwede, W. Skuballa, and U. Klar

Subcellular distribution of epothilones in human tumor cells
PNAS 2001 98: 11743-11748; published online before print September 18, 2001, 10.1073/pnas.171023398 [Abstract] [Full Text] [PDF]  

Physiology

Michal Hershfinkel, Arie Moran, Nili Grossman, and Israel Sekler

A zinc-sensing receptor triggers the release of intracellular Ca²⁺ and regulates ion transport
PNAS 2001 98: 11749-11754. [Abstract] [Full Text] [PDF]  

Lakshmanaswamy Rajkumar, Raphael C. Guzman, Jason Yang, Gudmundur Thordarson, Frank Talamantes, and Satyabrata Nandi

Short-term exposure to pregnancy levels of estrogen prevents mammary carcinogenesis
PNAS 2001 98: 11755-11759. [Abstract] [Full Text] [PDF]  

William A. Chutkow, Varman Samuel, Polly A. Hansen, Jielin Pu, Carmen R. Valdivia, Jonathan C. Makielski, and Charles F. Burant

Disruption of Sur2-containing K_ATP channels enhances insulin-stimulated glucose uptake in skeletal muscle
PNAS 2001 98: 11760-11764; published online before print September 18, 2001, 10.1073/pnas.201390398 [Abstract] [Full Text] [PDF]  

Marek Jankowski, Grazyna Rachelska, Wang Donghao, Samuel M. McCann, and Jolanta Gutkowska

Estrogen receptors activate atrial natriuretic peptide in the rat heart
PNAS 2001 98: 11765-11770; published online before print September 18, 2001, 10.1073/pnas.201394198 [Abstract] [Full Text] [PDF]  

Kuang-Tse Huang, Tae H. Han, Daniel R. Hyduke, Mark W. Vaughn, Helga Van Herle, Travis W. Hein, Cuihua Zhang, Lih Kuo, and James C. Liao

Modulation of nitric oxide bioavailability by erythrocytes
PNAS 2001 98: 11771-11776. [Abstract] [Full Text] [PDF]  

Guillermo Vazquez, Jean-Philippe Lievremont, Gary St. J. Bird, and James W. Putney Jr.

Human Trp3 forms both inositol trisphosphate receptor-dependent and receptor-independent store-operated cation channels in DT40 avian B lymphocytes
PNAS 2001 98: 11777-11782; published online before print September 11, 2001, 10.1073/pnas.201238198 [Abstract] [Full Text] [PDF]  

Sharada Karanth, Wen H. Yu, Anna Walczewska, Claudio A. Mastronardi, and Samuel M. McCann

Ascorbic acid stimulates gonadotropin release by autocrine action by means of NO
PNAS 2001 98: 11783-11788; published online before print September 18, 2001, 10.1073/pnas.191369398 [Abstract] [Full Text] [PDF]  

Plant Biology

Mari Shibata, Hiroshi Ohkawa, Takakazu Kaneko, Hideya Fukuzawa, Satoshi Tabata, Aaron Kaplan, and Teruo Ogawa

Distinct constitutive and low-CO₂-induced CO₂ uptake systems in cyanobacteria: Genes involved and their phylogenetic relationship with homologous genes in other organisms
PNAS 2001 98: 11789-11794; published online before print September 18, 2001, 10.1073/pnas.191258298 [Abstract] [Full Text] [PDF]  

Nathan Zenser, Amanda Ellsmore, Colin Leasure, and Judy Callis

Auxin modulates the degradation rate of Aux/IAA proteins
PNAS 2001 98: 11795-11800. [Abstract] [Full Text] [PDF]  

Uwe Rascher, Marc-Thorsten Hütt, Katharina Siebke, Barry Osmond, Friedrich Beck, and Ulrich Lüttge

Spatiotemporal variation of metabolism in a plant circadian rhythm: The biological clock as an assembly of coupled individual oscillators
PNAS 2001 98: 11801-11805. [Abstract] [Full Text] [PDF] [Supporting Movies]  

Sandra L. Stone, Linda W. Kwong, Kelly Matsudaira Yee, Julie Pelletier, Loïc Lepiniec, Robert L. Fischer, Robert B. Goldberg, and John J. Harada

LEAFY COTYLEDON2 encodes a B3 domain transcription factor that induces embryo development
PNAS 2001 98: 11806-11811. [Abstract] [Full Text] [PDF]  

Stéphane Pien, Joanna Wyrzykowska, Simon McQueen-Mason, Cheryl Smart, and Andrew Fleming From the Cover: Local expression of expansin induces the entire process of leaf development and modifies leaf shape PNAS 2001 98: 11812-11817; published online before print September 18, 2001, 10.1073/pnas.191380498 [Abstract] [Full Text] [PDF]

Psychology

Anne J. Blood and Robert J. Zatorre

Intensely pleasurable responses to music correlate with activity in brain regions implicated in reward and emotion
PNAS 2001 98: 11818-11823. [Abstract] [Full Text] [PDF] [Supporting Information]  

A. Courtney DeVries, Hung-Dong Joh, Ora Bernard, Kimihiko Hattori, Patricia D. Hurn, Richard J. Traystman, and Nabil J. Alkayed

Social stress exacerbates stroke outcome by suppressing Bcl-2 expression
PNAS 2001 98: 11824-11828; published online before print September 11, 2001, 10.1073/pnas.201215298 [Abstract] [Full Text] [PDF]  

CORRECTIONS

Correction for vol. 98, p. 10557 [Full Text] [PDF]