Table S1.

Stereotaxic coordinates of local BOLD maxima of the reported contrasts

ContrastBrain regionAnatomy*HemisphereSizeTPxyz
Visual sicknessSuperior frontal gyrusRight483.81<0.00124954
Middle frontal gyrusLeft674.01<0.001−33489
Insula, auditory cortexTE 1.0Right643.88<0.00133−270
Middle cingulate cortexRight444.30<0.00118−1239
Olfactory sicknessMiddle frontal gyrusLeft463.85<0.001−304827
Inferior frontopolar gyrusFp2Right/left1394.18<0.00112540
Posterior orbital gyrusFo3Right1353.97<0.0012427−15
Orbitofrontal cortexRight724.40<0.0013639−6
Entorhinal/piriform cortexRight504.26<0.0019−9−24
Mediodorsal ThalamusRight/left1053.91<0.0016−156
Olfactory–visual sicknessSuperior frontal gyrus4pRight1744.22<0.00130−1851
Superior frontal gyrusRight854.89<0.001181254
Superior frontal gyrusLeft624.13<0.001−151848
Middle frontal gyrusFp1Left944.22<0.001−335121
Inferior frontal gyrus, temporal poleLeft633.75<0.001−5121−21
Orbitofrontal cortexRight804.12<0.0013639−6
Mediodorsal thalamusRight/left1924.22<0.0013−156
CerebellumLob VIIa crus ILeft1054.30<0.001−33−66−33
Superadditive sicknessMotor cortex1, 2Left68611.58<0.001−39−2460
Superior parietal gyrus7P, 7A, hlP3Right1607.25<0.00118−7254
Intraparietal sulcushlP2, 3, Area 2PFt,Right295.450.00542−4548
Middle occipital gyrushOc4d, hOc3dLeft837.01<0.001−27−9024
Middle occipital gyrushOc4d, 3dRight185.730.00227−9330
Calcarine/lingual gyrushOC1, 2, 3vLeft/right3589.57<0.001−9−93−3
CerebellumLob VI, V, HemRight466.87<0.00121−51−24
PPI interaction term: IPS X superadditive sicknessPrecentral gyrusLeft135.340.009−21−7551
Superior parietal lobe7A, PRight135.350.00154330
Inferior parietal lobehlP2, 3, PFm, Area 2Right1357.03<0.00145−4248
Supramarginal gyrusPF, PFop, PFcm, PFtLeft405.370.008−51−3327
Superior/inferior temporal gyrushOc1, FG3, TE 1.2Right25626.43<0.0015700
Superior. temporal gyrusTE 1.2, 3Left4396.44<0.001−39−18−6
Inferior temporal gyrusFG2, hOc4IaLeft596.66<0.001−60−60−15
Temporal poleLeft145.650.003−546−36
Middle occipital gyrushOc4IaLeft215.530.004−57−696
Fusiform gyrusFG1, 3, 4, hOc4vRight155.300.01039−69−12
Precuneus5M, 5Ci, 7ARight/left5097.55<0.0016−4557
Middle cingulate cortexRight/left695.980.0016−1845
Anterior cingulate cortexRight/left125.280.01102730
Hippocampus/AmygdalaCA1, DGLeft575.960.001−30−12−27
CerebellumLob VIIIb, IXLeft246.010.001−15−63−48
BrainstemLeft115.270.011−12−27−36
  • Stereotaxic coordinates (MNI space) of local maxima of BOLD activation to visual sickness, olfactory sickness (t-contrasts from a random-effects GLM, T >3.14, cluster-level corrected, P < 0.05), olfactory–visual sickness (t-contrast from a random-effects GLM, T >3.14, cluster-level corrected, P < 0.05), and superadditive sickness (t-contrast from a random-effects GLM, T >4.82, peak-level whole-brain-corrected, P <0.05), and IPS X superadditive sickness (T >4.83, peak-level whole-brain-corrected, P < 0.05). Boldface indications of right and left indicate the hemisphere in which the activation peak maximum was found in case of bilateral activations.

  • * Probabilistic cytoarchitectonic maps for structure–function relationships in standard reference space were assigned using the Anatomy toolbox (56) (for labeling please refer to ref. 60).

  • Cluster surviving whole-brain peak-level correction for multiple comparisons.