Table S3.

Summary of the lifespan experiments

FiguresConditionsMaximum lifespan + SEM, dMedian lifespan + SEM, dNCensoredP value
Fig. 1AN2 + K12ΔtnaA25.5 ± 1.017.2 ± 0.853415<0.0001
N2 + K1227.7 ± 1.120.2 ± 0.767715
Fig. 1CN2 + K12ΔtnaA + vehicle29.0 ± 1.718.2 ± 0.55423<0.0001
N2 + K12ΔtnaA + indole29.6 ± 1.222.4 ± 1.24925
Fig. 1DN2 + K12 + vehicle32.5 ± 0.522 ± 12260<0.0001
N2 + K12 + indole36.5 ± 1.525.5 ± 1.52430
Fig. 1LW1118 + K12ΔtnaA103.0 ± 2.090.5 ± 2.51160<0.0001
W1118 + K12110.0 ± 4.0100.0 ± 5.0600
Fig. 2Aahr-1(ju145) + K12ΔtnaA31.3 ± 0.622.8 ± 1.5117120.15
ahr-1(ju145) + K1232.0 ± 0.622.3 ± 1.21125
Fig. 2Bahr-1(ia3) + K12ΔtnaA33.0 ± 0.724.8 ± 0.89500.065
ahr-1(ia3) + K1231.5 ± 0.523.0 ± 0.91040
Fig. 2Dahr-1(ju145) + K12ΔtnaA + vehicle28.7 ± 2.024.0 ± 2.09810.051
ahr-1(ju145) + K12ΔtnaA + indole29.0 ± 1.722.7 ± 2.31111
Fig. 2Eahr-1(ia3) + K12ΔtnaA + vehicle30.5 ± 1.521.5 ± 1.536830.36
ahr-1(ia3) + K12ΔtnaA + indole30.5 ± 1.520 ± 22582
Fig. S2Bsir-2.1(ok434) + K12ΔtnaA22.0 ± 0.018.0 ± 0.0790<0.0001
sir-2.1(ok434) + K1224.0 ± 0.021.0 ± 1.0930
Fig. S2Cskn-1(ju169) + K12ΔtnaA19.0 ± 0.012.5 ± 0.5800<0.0001
skn-1(ju169) + K1219.0 ± 0.015.0 ± 1.0790
Fig. S2Ddaf-16(m26) + K12ΔtnaA23.0 ± 0.018.0 ± 0.0887<0.0001
daf-16(m26) + K1223.0 ± 0.020.3 ± 0.3595
Fig. S2Ecat-2(e1112) + K12ΔtnaA21.3 ± 0.717.6 ± 1.55710<0.0001
cat-2(e1112) + K1224.0 ± 1.020.0 ± 0.0562
Fig. S2Fdop-3(vs.106) + K12ΔtnaA30.0 ± 0.022.0 ± 1.0910<0.0001
dop-3(vs.106) + K1230.0 ± 0.025.0 ± 0.0900
  • P values were obtained from log-rank (Mantel–Cox) test.