Table 1.

Distribution of SOD1:c.118G>A genotypes among DM-affected and control dogs

BreedDM stringency 1AA/AG/GGDM stringencies 1 and 2AA/AG/GGDM stringencies 1 to 3AA/AG/GGDM stringencies 1 to 4AA/AG/GGAffected breed controls AA/AG/GGOther breed controls AA/AG/GG
Boxer9/0/0*10/0/0*12/0/0*22/0/0**86/57/14
Chesapeake Bay retriever7/0/0**9/0/0**9/0/0**10/0/0**7/25/21
German shepherd dog2/0/0*4/0/0**4/0/0**4/0/1**7/30/83
Pembroke Welsh corgi25/0/0**30/0/0**35/0/0**50/1/1**44/14/9
Rhodesian ridgeback3/0/0*6/0/0**6/0/0**10/1/0**4/15/21
All affected breeds46/0/0***59/0/0***66/0/0***96/2/2***148/141/1480/5/115***
  • *, Different than breed-specific controls at P < 0.01;

  • **, different than breed-specific controls at P < 0.001;

  • ***, different than all affected breed controls at P < 0.00001.