Table 1.

Our results versus HMMER 3.0

Six-bladedSeven-bladedEight-bladed
TNHMMERSMURF(P)SMURFHMMERSMURF(P)SMURFHMMERSMURF(P)SMURF
97%5220808023870400
96%562480803387204040
95%643680874793204040
94%683684905393406040
93%6848849053974010040
92%6860889057974010040
91%6860929057974010040
90%686092935710060100100

The numbers represent the percent of true positives correct for a given threshold of percent of true negatives (TN) on a leave-superfamily-out cross-validation. Best results (in bold) come from SMURF, or, on the eight-bladed propellers, SMURF(P) which reweights SMURF away from the HMM entirely to consider only our pairwise scores. Note that structures with fewer than 150 residues were removed from the test set, as they are too short to fold into β-propellers with six or more blades.