Table 1

Data obtained from subjects in group I while they rested quietly but awake with their eyes closed

AreaxyzOEFPCBFPCMRO2P
AM 31/7−5−49401.0100.621.374*<0.00011.397*<0.0001
BL 40−53−39420.9010.070.735*<0.00010.695*<0.0001
CL 39/19−45−67360.9870.660.813*0.00080.805*0.0003
DR 4045−57340.9780.261.0020.960.9980.97
EL lateral 8−2727400.9810.520.9910.740.9860.74
FL 8/9−1141420.9020.040.8740.0060.803*0.001
GR 8/9549360.8870.0040.8930.010.813*0.001
HL 9−1555260.9430.350.813*0.00010.785*0.002
IL 10−195780.9710.060.9400.010.9270.01
JM 10−147−40.9330.011.284*<0.00011.203*<0.0001
KL 10/47−3345−60.9300.250.9200.030.8790.04
LM 32331−100.9460.201.1110.0051.0580.26
ML 20−49−19−180.9720.460.821*<0.00010.814*0.0002
  • The values for OEF, CBF, and CMRO2 are expressed as local-to-global ratios (see Methods). For the 19 subjects in group I the global values for OEF and CBF (± SD) were 0.40 ± 0.09 (dimensionless) and 46 ± 8 ml/(min × 100 g), respectively. The mean arterial oxygen content for this group was 16.6 ± 0.16 ml/ml. From these data quantitative images of the CMRO2 were created that yielded a mean cerebral hemisphere value of 2.94 ± 0.41 ml/(min × 100 g) or 1.31 ± 0.18 μmol/(min × g). The asterisks denote values that differ significantly from the global mean after correction for multiple comparisons.