Table 1.

Liver content of ATP, ADP, and AMP in calorie-restricted WT and Goat−/− mice injected with GH

Liver content, nmol/mg protein
ATPADPAMP
Genotype−GH+GH−GH+GH−GH+GH
WT2.3 ± 0.22.6 ± 0.12.6 ± 0.32.5 ± 0.33.5 ± 0.72.8 ± 0.6
Goat−/−1.6 ± 0.1**1.5 ± 0.1***3.2 ± 0.43.3 ± 0.2*7.9 ± 1.4**8.3 ± 1.3***
  • These data were obtained from the mice described in Fig. 6 (13 mice in each group). Liver content of ATP and ADP was measured as described in Materials and Methods. Liver content of AMP was calculated according to Burgess et al. (22). Each value represents mean ± SEM of data from 13 mice. Asterisks denote level of statistical significance between vehicle or GH-injected WT vs. Goat−/− mice: *P < 0.05; **P < 0.01; ***P < 0.001.