Table 1.

TimeSignature predictive genes

GeneFreq.GeneFreq.GeneFreq.
DDIT41.00GZMB0.58CAMKK10.17
GHRL1.00CLEC10 A0.50DTYMK0.17
PER11.00PDK10.50NPEPL10.08
EPHX20.92GPCPD10.50MS4A30.08
GNG20.83MUM10.33IL13RA10.08
IL1B0.83STIP10.33ID30.08
DHRS130.83CHSY10.25MEGF60.08
NR1D10.75AK50.25TCN10.08
ZNF4380.75CYB5610.25NSUN30.08
NR1D20.75SLPI0.25POLH0.08
CD380.75PARP20.25SYT110.08
TIAM20.75PGPEP10.17SH2D1B0.08
CD1C0.75C12orf750.17REM20.08
LLGL20.58FKBP40.17
  • A set of 41 genes is sufficient for accurate TimeSignature prediction. As described in the text, the predictors may vary slightly depending on the training data; the frequency with which each gene was selected as a predictor across 12 repeated runs using different training samples is given. Eighteen are selected the majority of the time; the remaining “auxiliary” predictors vary from run to run. Genes are sorted in order of selection frequency.