Table 1.

Patient cardiac and hiPSC lines used

ClassificationPatient/lineGeneAge, ySexSourceQ-FISH (n)
Human cardiac samples
 HealthyCon#1NA35MaleUniversity of British Columbia70
 HealthyCon#2NA21MaleUniversity of British Columbia69
 HealthyCon#3NA21MaleUniversity of British Columbia65
 HealthyCon#4NA47MaleUniversity of British Columbia124
 HealthyCon#5NA41MaleUniversity of British Columbia128
 HealthyCon#6NA32MaleUniversity of British Columbia121
 HealthyCon#7NA49FemaleUniversity of British Columbia99
 HealthyCon#8NA53FemaleUniversity of British Columbia214
 HealthyCon#9NA54FemaleUniversity of British Columbia220
 HCMTNNI3TNNI3 (p.Arg186Gln)60MaleStanford University72
 HCMMYBPC3MYBPC3 (IVS11-9G > A)25FemaleStanford University36
 HCMMYH7MYH7 (p.Ala26Val)56FemaleStanford University32
 DCMDMD#1DMD13MaleHarvard University42
 DCMDMD#2DMD15MaleHarvard University94
 DCMDMD#3DMD17MaleJohns Hopkins University65
 DCMDMD#4DMD19MaleUniversity of Wisconsin72
 DCMTNNT2TNNT2 (p.R173W)15MaleStanford University804
 DCMTitin#1TTN (c.92569+1G > C)40MaleHarvard University245
 DCMTitin#2TTN (c.44725+2delT)50MaleHarvard University113
 DCMTitin#3TTN (26211W>*stop)50MaleHarvard University55
Patient hiPSC lines
 HealthyCon#1Healthy control45MaleStanford University92
 HealthyCon#2Family control from TNNT216MaleStanford University40
 HealthyCon#3Family control from TNNT277MaleStanford University44
 HealthyCon#4Isogenic control of TTN#162MaleHarvard University100
 HealthyCon#5Family control from TTN#248FemaleHarvard University210
 HCMMYBPC3#1MYBPC3 (R943x)29MaleStanford University519
 HCMMYH7#1MYH7 (R723C)32MaleStanford University115
 HCMMYH7#2MYH7 (R403Q)45FemaleStanford University79
 HCMMYH7#3MYH7 (R719W)34MaleStanford University54
 HCMMYH7#4MYH7 (R663H)57MaleStanford University37
 DCMDMD#1DMD (c.3638_3650del)6MaleStanford University129
 DCMDMD#2DMD (c.6599 C > G)12MaleStanford University48
 DCMDMD#3DMD (c.9204_9207del)9MaleStanford University164
 DCMTNNT2#1TNNT2 (p.R173W)45MaleStanford University117
 DCMTNNT2#2TNNT2 (p.R173W)39MaleStanford University131
 DCMTNNT2#3TNNT2 (p.R173W)15MaleStanford University50
 DCMTTN#1TTN (cN22577fs+/−)62MaleHarvard University184
 DCMTTN#2TTN (c.67745delT)15MaleHarvard University133
  • NA, not applicable.