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The 50 Most-Frequently Read Articles
in PNAS during March 2008 -- updated monthly

Most-read rankings are recalculated at the beginning of the month and are based on full-text and pdf views.

1.  Francesco Fornai, Patrizia Longone, Luisa Cafaro, Olga Kastsiuchenka, Michela Ferrucci, Maria Laura Manca, Gloria Lazzeri, Alida Spalloni, Natascia Bellio, Paola Lenzi, Nicola Modugno, Gabriele Siciliano, Ciro Isidoro, Luigi Murri, Stefano Ruggieri, Antonio Paparelli
  Lithium delays progression of amyotrophic lateral sclerosis
  Proc. Natl. Acad. Sci. USA Feb 12, 2008; 105: 2052-2057.
(In "Medical Sciences")   [Abstract]     [Full Text]     [PDF]
 
2.  James Hansen, Makiko Sato, Reto Ruedy, Ken Lo, David W. Lea, Martin Medina-Elizade
  Global temperature change
  Proc. Natl. Acad. Sci. USA Sep 26, 2006; 103: 14288-14293.
(In "Environmental Sciences-PS")   [Abstract]     [Full Text]     [PDF]
 
3.  W. E. Lowry, L. Richter, R. Yachechko, A. D. Pyle, J. Tchieu, R. Sridharan, A. T. Clark, K. Plath
  Generation of human induced pluripotent stem cells from dermal fibroblasts
  Proc. Natl. Acad. Sci. USA Feb 26, 2008; 105: 2883-2888.
(In "Cell Biology")   [Abstract]     [Full Text]     [PDF]
 
4.  Antoine Lutz, Lawrence L. Greischar, Nancy B. Rawlings, Matthieu Ricard, Richard J. Davidson
  Long-term meditators self-induce high-amplitude gamma synchrony during mental practice
  Proc. Natl. Acad. Sci. USA Nov 16, 2004; 101: 16369-16373.
(In "Neuroscience")   [Abstract]     [Full Text]     [PDF]
 
5.  Jason Hill, Erik Nelson, David Tilman, Stephen Polasky, Douglas Tiffany
  From the Cover: Environmental, economic, and energetic costs and benefits of biodiesel and ethanol biofuels
  Proc. Natl. Acad. Sci. USA Jul 25, 2006; 103: 11206-11210.
(In "Sustainability_Science-SS")   [Abstract]     [Full Text]     [PDF]
 
6.  Mark C. Enright, D. Ashley Robinson, Gaynor Randle, Edward J. Feil, Hajo Grundmann, Brian G. Spratt
  The evolutionary history of methicillin-resistant Staphylococcus aureus (MRSA)
  Proc. Natl. Acad. Sci. USA May 28, 2002; 99: 7687-7692.
(In "Microbiology")   [Abstract]     [Full Text]     [PDF]
 
7.  Marius Gilbert, Xiangming Xiao, Dirk U. Pfeiffer, M. Epprecht, Stephen Boles, Christina Czarnecki, Prasit Chaitaweesub, Wantanee Kalpravidh, Phan Q. Minh, M. J. Otte, Vincent Martin, Jan Slingenbergh
  Mapping H5N1 highly pathogenic avian influenza risk in Southeast Asia
  Proc. Natl. Acad. Sci. USA Mar 25, 2008; 105: 4769-4774.
(In "Ecology")   [Abstract]     [Full Text]     [PDF]
 
8.  Amit Agrawal, Rajesh Deo, Geoffrey D. Wang, May D. Wang, Shuming Nie
  Nanometer-scale mapping and single-molecule detection with color-coded nanoparticle probes
  Proc. Natl. Acad. Sci. USA Mar 04, 2008; 105: 3298-3303.
(In "Biophysics")   [Abstract]     [Full Text]     [PDF]
 
9.  Yousin Suh, Gil Atzmon, Mi-Ook Cho, David Hwang, Bingrong Liu, Daniel J. Leahy, Nir Barzilai, Pinchas Cohen
  Functionally significant insulin-like growth factor I receptor mutations in centenarians
  Proc. Natl. Acad. Sci. USA Mar 04, 2008; 105: 3438-3442.
(In "Genetics")   [Abstract]     [Full Text]     [PDF]
 
10.  Deborah S. Rogers, Paul R. Ehrlich
  From the Cover: Natural selection and cultural rates of change
  Proc. Natl. Acad. Sci. USA Mar 04, 2008; 105: 3416-3420.
(In "Evolution")   [Abstract]     [Full Text]     [PDF]
 
11.  Damien A. Fair, Alexander L. Cohen, Nico U. F. Dosenbach, Jessica A. Church, Francis M. Miezin, Deanna M. Barch, Marcus E. Raichle, Steven E. Petersen, Bradley L. Schlaggar
  The maturing architecture of the brain's default network
  Proc. Natl. Acad. Sci. USA Mar 11, 2008; 105: 4028-4032.
(In "Neuroscience")   [Abstract]     [Full Text]     [PDF]
 
12.  J. E. Hirsch
  An index to quantify an individual's scientific research output
  Proc. Natl. Acad. Sci. USA Nov 15, 2005; 102: 16569-16572.
(In "Physics")   [Abstract]     [Full Text]     [PDF]
 
13.  Michael B. Eisen, Paul T. Spellman, Patrick O. Brown, David Botstein
  Cluster analysis and display of genome-wide expression patterns
  Proc. Natl. Acad. Sci. USA Dec 08, 1998; 95: 14863-14868.
(In "Genetics")   [Abstract]     [Full Text]     [PDF]
 
14.  Igor Goychuk, Peter Hänggi
  Ion channel gating: A first-passage time analysis of the Kramers type
  Proc. Natl. Acad. Sci. USA Mar 19, 2002; 99: 3552-3556.
(In "Biophysics")   [Abstract]     [Full Text]     [PDF]
 
15.  Timothy M. Lenton, Hermann Held, Elmar Kriegler, Jim W. Hall, Wolfgang Lucht, Stefan Rahmstorf, Hans Joachim Schellnhuber
  Inaugural Article: Tipping elements in the Earth's climate system
  Proc. Natl. Acad. Sci. USA Feb 12, 2008; 105: 1786-1793.
(In "Sustainability Science-PS")   [Abstract]     [Full Text]     [PDF]
 
16.  David Cesarini, Christopher T. Dawes, James H. Fowler, Magnus Johannesson, Paul Lichtenstein, Björn Wallace
  Heritability of cooperative behavior in the trust game
  Proc. Natl. Acad. Sci. USA Mar 11, 2008; 105: 3721-3726.
(In "Anthropology-BS")   [Abstract]     [Full Text]     [PDF]
 
17.  John F. Nash
  Equilibrium Points in n-Person Games
  Proc. Natl. Acad. Sci. USA Jan 15, 1950; 36: 48-49.
(In "Journal_Article")   [PDF]
 
18.  Adrianna C. Jenkins, C. Neil Macrae, Jason P. Mitchell
  From the Cover: Repetition suppression of ventromedial prefrontal activity during judgments of self and others
  Proc. Natl. Acad. Sci. USA Mar 18, 2008; 105: 4507-4512.
(In "Psychology-BS")   [Abstract]     [Full Text]     [PDF]
 
19.  Andrew M. Bellinger, Steven Reiken, Miroslav Dura, Peter W. Murphy, Shi-Xian Deng, Donald W. Landry, David Nieman, Stephan E. Lehnart, Mahendranauth Samaru, Alain LaCampagne, Andrew R. Marks
  Remodeling of ryanodine receptor complex causes "leaky" channels: A molecular mechanism for decreased exercise capacity
  Proc. Natl. Acad. Sci. USA Feb 12, 2008; 105: 2198-2202.
(In "Physiology")   [Abstract]     [Full Text]     [PDF]
 
20.  Katherine M. Thibault, James H. Brown
  Impact of an extreme climatic event on community assembly
  Proc. Natl. Acad. Sci. USA Mar 04, 2008; 105: 3410-3415.
(In "Ecology")   [Abstract]     [Full Text]     [PDF]
 
21.  James Tsai, John T. Lee, Weiru Wang, Jiazhong Zhang, Hanna Cho, Shumeye Mamo, Ryan Bremer, Sam Gillette, Jun Kong, Nikolas K. Haass, Katrin Sproesser, Ling Li, Keiran S. M. Smalley, Daniel Fong, Yong-Liang Zhu, Adhirai Marimuthu, Hoa Nguyen, Billy Lam, Jennifer Liu, Ivana Cheung, Julie Rice, Yoshihisa Suzuki, Catherine Luu, Calvin Settachatgul, Rafe Shellooe, John Cantwell, Sung-Hou Kim, Joseph Schlessinger, Kam Y. J. Zhang, Brian L. West, Ben Powell, Gaston Habets, Chao Zhang, Prabha N. Ibrahim, Peter Hirth, Dean R. Artis, Meenhard Herlyn, Gideon Bollag
  From the Cover: Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity
  Proc. Natl. Acad. Sci. USA Feb 26, 2008; 105: 3041-3046.
(In "Medical Sciences")   [Abstract]     [Full Text]     [PDF]
 
22.  Mathias Ehrich, Julia Turner, Peter Gibbs, Lara Lipton, Mara Giovanneti, Charles Cantor, Dirk van den Boom
  Cytosine methylation profiling of cancer cell lines
  Proc. Natl. Acad. Sci. USA Mar 25, 2008; 105: 4844-4849.
(In "Medical Sciences")   [Abstract]     [Full Text]     [PDF]
 
23.  Daehyun Baek, Phil Green
  Sequence conservation, relative isoform frequencies, and nonsense-mediated decay in evolutionarily conserved alternative splicing
  Proc. Natl. Acad. Sci. USA Aug 25, 2005; doi: 10.1073/pnas.0506139102.
(In "Evolution")   [Abstract]     [PDF]
 
24.  Monica Uddin, Morris Goodman, Offer Erez, Roberto Romero, Guozhen Liu, Munirul Islam, Juan C. Opazo, Chet C. Sherwood, Lawrence I. Grossman, Derek E. Wildman
  Distinct genomic signatures of adaptation in pre- and postnatal environments during human evolution
  Proc. Natl. Acad. Sci. USA Mar 04, 2008; 105: 3215-3220.
(In "Evolution")   [Abstract]     [Full Text]     [PDF]
 
25.  Ramamurthy Mani, Robert P. St.Onge, John L. Hartman, Guri Giaever, Frederick P. Roth
  Defining genetic interaction
  Proc. Natl. Acad. Sci. USA Mar 04, 2008; 105: 3461-3466.
(In "Genetics")   [Abstract]     [Full Text]     [PDF]
 
26.  Marcus Krüger, Irina Kratchmarova, Blagoy Blagoev, Yu-Hua Tseng, C. Ronald Kahn, Matthias Mann
  Dissection of the insulin signaling pathway via quantitative phosphoproteomics
  Proc. Natl. Acad. Sci. USA Feb 19, 2008; 105: 2451-2456.
(In "Cell Biology")   [Abstract]     [Full Text]     [PDF]
 
27.  Jorge Frias-Lopez, Yanmei Shi, Gene W. Tyson, Maureen L. Coleman, Stephan C. Schuster, Sallie W. Chisholm, Edward F. DeLong
  From the Cover: Microbial community gene expression in ocean surface waters
  Proc. Natl. Acad. Sci. USA Mar 11, 2008; 105: 3805-3810.
(In "Environmental_Sciences-BS")   [Abstract]     [Full Text]     [PDF]
 
28.  David Jackson, Md. Jaber Hossain, Danielle Hickman, Daniel R. Perez, Robert A. Lamb
  A new influenza virus virulence determinant: The NS1 protein four C-terminal residues modulate pathogenicity
  Proc. Natl. Acad. Sci. USA Mar 11, 2008; doi: 10.1073/pnas.0800482105.
(In "Microbiology")   [Abstract]     [PDF]
 
29.  Francisco J. Ayala
  Science, evolution, and creationism
  Proc. Natl. Acad. Sci. USA Jan 08, 2008; 105: 3-4.
(In "Editorial")   [Full Text]     [PDF]
 
30.  Carola Holweg, Peter Nick
  Retraction for Holweg and Nick, Arabidopsis myosin XI mutant is defective in organelle movement and polar auxin transport
  Proc. Natl. Acad. Sci. USA Mar 04, 2008; 105: 3658-3658.
(In "Retraction")   [Full Text]     [PDF]
 
31.  Suling Liu, Christophe Ginestier, Emmanuelle Charafe-Jauffret, Hailey Foco, Celina G. Kleer, Sofia D. Merajver, Gabriela Dontu, Max S. Wicha
  BRCA1 regulates human mammary stem/progenitor cell fate
  Proc. Natl. Acad. Sci. USA Feb 05, 2008; 105: 1680-1685.
(In "Medical Sciences")   [Abstract]     [Full Text]     [PDF]
 
32.  Jenny R. Saffran, Ann Senghas, John C. Trueswell
  The acquisition of language by children
  Proc. Natl. Acad. Sci. USA Nov 06, 2001; 98: 12874-12875.
(In "From The Academy")   [Full Text]     [PDF]
 
33.  Marios Giannakis, Swaine L. Chen, Sherif M. Karam, Lars Engstrand, Jeffrey I. Gordon
  Helicobacter pylori evolution during progression from chronic atrophic gastritis to gastric cancer and its impact on gastric stem cells
  Proc. Natl. Acad. Sci. USA Mar 10, 2008; doi: 10.1073/pnas.0800668105.
(In "Microbiology")   [Abstract]     [PDF]
 
34.  M. Elizabeth Halloran, Neil M. Ferguson, Stephen Eubank, Ira M. Longini, Derek A. T. Cummings, Bryan Lewis, Shufu Xu, Christophe Fraser, Anil Vullikanti, Timothy C. Germann, Diane Wagener, Richard Beckman, Kai Kadau, Chris Barrett, Catherine A. Macken, Donald S. Burke, Philip Cooley
  Modeling targeted layered containment of an influenza pandemic in the United States
  Proc. Natl. Acad. Sci. USA Mar 10, 2008; doi: 10.1073/pnas.0706849105.
(In "Environmental_Sciences")   [Abstract]     [PDF]
 
35.  M. R. Schmer, K. P. Vogel, R. B. Mitchell, R. K. Perrin
  Net energy of cellulosic ethanol from switchgrass
  Proc. Natl. Acad. Sci. USA Jan 15, 2008; 105: 464-469.
(In "Agricultural Sciences")   [Abstract]     [Full Text]     [PDF]
 
36.  Angela C. Poole, Ruth E. Thomas, Laurie A. Andrews, Heidi M. McBride, Alexander J. Whitworth, Leo J. Pallanck
  The PINK1/Parkin pathway regulates mitochondrial morphology
  Proc. Natl. Acad. Sci. USA Feb 05, 2008; 105: 1638-1643.
(In "Genetics")   [Abstract]     [Full Text]     [PDF]
 
37.  Min Li, Baohong Wang, Menghui Zhang, Mattias Rantalainen, Shengyue Wang, Haokui Zhou, Yan Zhang, Jian Shen, Xiaoyan Pang, Meiling Zhang, Hua Wei, Yu Chen, Haifeng Lu, Jian Zuo, Mingming Su, Yunping Qiu, Wei Jia, Chaoni Xiao, Leon M. Smith, Shengli Yang, Elaine Holmes, Huiru Tang, Guoping Zhao, Jeremy K. Nicholson, Lanjuan Li, Liping Zhao
  Symbiotic gut microbes modulate human metabolic phenotypes
  Proc. Natl. Acad. Sci. USA Feb 12, 2008; 105: 2117-2122.
(In "Microbiology")   [Abstract]     [Full Text]     [PDF]
 
38.  Jean William Pape, Paul Farmer, Serena Koenig, Daniel Fitzgerald, Peter Wright, Warren Johnson
  The epidemiology of AIDS in Haiti refutes the claims of Gilbert et al.
  Proc. Natl. Acad. Sci. USA Mar 11, 2008; 105: 13-13.
(In "Letters")   [Full Text]     [PDF]
 
39.  Madhu S. Kumar, Stefan J. Erkeland, Ryan E. Pester, Cindy Y. Chen, Margaret S. Ebert, Phillip A. Sharp, Tyler Jacks
  Suppression of non-small cell lung tumor development by the let-7 microRNA family
  Proc. Natl. Acad. Sci. USA Mar 11, 2008; 105: 3903-3908.
(In "Medical Sciences")   [Abstract]     [Full Text]     [PDF]
 
40.  Myung Soo Cho, Young-Eun Lee, Ji Young Kim, Seungsoo Chung, Yoon Hee Cho, Dae-Sung Kim, Sang-Moon Kang, Haksup Lee, Myung-Hwa Kim, Jeong-Hoon Kim, Joong Woo Leem, Sun Kyung Oh, Young Min Choi, Dong-Youn Hwang, Jin Woo Chang, Dong-Wook Kim
  Highly efficient and large-scale generation of functional dopamine neurons from human embryonic stem cells
  Proc. Natl. Acad. Sci. USA Mar 04, 2008; 105: 3392-3397.
(In "Developmental Biology")   [Abstract]     [Full Text]     [PDF]
 
41.  Ardian Jusufi, Daniel I. Goldman, Shai Revzen, Robert J. Full
  From the Cover: Active tails enhance arboreal acrobatics in geckos
  Proc. Natl. Acad. Sci. USA Mar 18, 2008; 105: 4215-4219.
(In "Evolution")   [Abstract]     [Full Text]     [PDF]
 
42.  Kalai Mathee, Giri Narasimhan, Camilo Valdes, Xiaoyun Qiu, Jody M. Matewish, Michael Koehrsen, Antonis Rokas, Chandri N. Yandava, Reinhard Engels, Erliang Zeng, Raquel Olavarietta, Melissa Doud, Roger S. Smith, Philip Montgomery, Jared R. White, Paul A. Godfrey, Chinnappa Kodira, Bruce Birren, James E. Galagan, Stephen Lory
  Dynamics of Pseudomonas aeruginosa genome evolution
  Proc. Natl. Acad. Sci. USA Feb 26, 2008; 105: 3100-3105.
(In "Microbiology")   [Abstract]     [Full Text]     [PDF]
 
43.  Raymond E. Goldstein, Idan Tuval, Jan-Willem van de Meent
  From the Cover: Microfluidics of cytoplasmic streaming and its implications for intracellular transport
  Proc. Natl. Acad. Sci. USA Mar 11, 2008; 105: 3663-3667.
(In "Biophysics")   [Abstract]     [Full Text]     [PDF]
 
44.  Anirban Bandyopadhyay, Somobrata Acharya
  A 16-bit parallel processing in a molecular assembly
  Proc. Natl. Acad. Sci. USA Mar 11, 2008; 105: 3668-3672.
(In "Applied Physical Sciences")   [Abstract]     [Full Text]     [PDF]
 
45.  John Damuth
  Scaling of growth: Plants and animals are not so different
  Proc. Natl. Acad. Sci. USA Feb 27, 2001; 98: 2113-2114.
(In "Commentary")   [Full Text]     [PDF]
 
46.  Cheng Lu, Dong-Hoon Jeong, Karthik Kulkarni, Manoj Pillay, Kan Nobuta, Rana German, Shawn R. Thatcher, Christopher Maher, Lifang Zhang, Doreen Ware, Bin Liu, Xiaofeng Cao, Blake C. Meyers, Pamela J. Green
  Genome-wide analysis for discovery of rice microRNAs reveals natural antisense microRNAs (nat-miRNAs)
  Proc. Natl. Acad. Sci. USA Mar 25, 2008; 105: 4951-4956.
(In "Plant Biology")   [Abstract]     [Full Text]     [PDF]
 
47.  Eric P. Meyer, Alexandra Ulmann-Schuler, Matthias Staufenbiel, Thomas Krucker
  Altered morphology and 3D architecture of brain vasculature in a mouse model for Alzheimer's disease
  Proc. Natl. Acad. Sci. USA Mar 04, 2008; 105: 3587-3592.
(In "Neuroscience")   [Abstract]     [Full Text]     [PDF]
 
48.  Eric Bonabeau
  Agent-based modeling: Methods and techniques for simulating human systems
  Proc. Natl. Acad. Sci. USA May 14, 2002; 99: 7280-7287.
(In "Colloquium")   [Abstract]     [Full Text]     [PDF]
 
49.  Stanley B. Prusiner
  Prions
  Proc. Natl. Acad. Sci. USA Nov 10, 1998; 95: 13363-13383.
(In "Nobel")   [Abstract]     [Full Text]     [PDF]
 
50.  Ailan Guo, Judit Villén, Jon Kornhauser, Kimberly A. Lee, Matthew P. Stokes, Klarisa Rikova, Anthony Possemato, Julie Nardone, Gregory Innocenti, Randall Wetzel, Yi Wang, Joan MacNeill, Jeffrey Mitchell, Steven P. Gygi, John Rush, Roberto D. Polakiewicz, Michael J. Comb
  Signaling networks assembled by oncogenic EGFR and c-Met
  Proc. Natl. Acad. Sci. USA Jan 15, 2008; 105: 692-697.
(In "Medical Sciences")   [Abstract]     [Full Text]     [PDF]
 
  
Last Updated: 04/24/2008 10:57:26