Most-read rankings are recalculated at the beginning of the month and are based on full-text and pdf views.
| 1. | Francesco Fornai, Patrizia Longone, Luisa Cafaro, Olga Kastsiuchenka, Michela Ferrucci, Maria Laura Manca, Gloria Lazzeri, Alida Spalloni, Natascia Bellio, Paola Lenzi, Nicola Modugno, Gabriele Siciliano, Ciro Isidoro, Luigi Murri, Stefano Ruggieri, Antonio Paparelli | ||
| Lithium delays progression of amyotrophic lateral sclerosis | |||
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Proc. Natl. Acad. Sci. USA Feb 12, 2008; 105: 2052-2057.
(In "Medical Sciences") |
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| 2. | James Hansen, Makiko Sato, Reto Ruedy, Ken Lo, David W. Lea, Martin Medina-Elizade | ||
| Global temperature change | |||
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Proc. Natl. Acad. Sci. USA Sep 26, 2006; 103: 14288-14293.
(In "Environmental Sciences-PS") |
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| 3. | W. E. Lowry, L. Richter, R. Yachechko, A. D. Pyle, J. Tchieu, R. Sridharan, A. T. Clark, K. Plath | ||
| Generation of human induced pluripotent stem cells from dermal fibroblasts | |||
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Proc. Natl. Acad. Sci. USA Feb 26, 2008; 105: 2883-2888.
(In "Cell Biology") |
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| 4. | Antoine Lutz, Lawrence L. Greischar, Nancy B. Rawlings, Matthieu Ricard, Richard J. Davidson | ||
| Long-term meditators self-induce high-amplitude gamma synchrony during mental practice | |||
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Proc. Natl. Acad. Sci. USA Nov 16, 2004; 101: 16369-16373.
(In "Neuroscience") |
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| 5. | Jason Hill, Erik Nelson, David Tilman, Stephen Polasky, Douglas Tiffany | ||
| From the Cover: Environmental, economic, and energetic costs and benefits of biodiesel and ethanol biofuels | |||
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Proc. Natl. Acad. Sci. USA Jul 25, 2006; 103: 11206-11210.
(In "Sustainability_Science-SS") |
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| 6. | Mark C. Enright, D. Ashley Robinson, Gaynor Randle, Edward J. Feil, Hajo Grundmann, Brian G. Spratt | ||
| The evolutionary history of methicillin-resistant Staphylococcus aureus (MRSA) | |||
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Proc. Natl. Acad. Sci. USA May 28, 2002; 99: 7687-7692.
(In "Microbiology") |
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| 7. | Marius Gilbert, Xiangming Xiao, Dirk U. Pfeiffer, M. Epprecht, Stephen Boles, Christina Czarnecki, Prasit Chaitaweesub, Wantanee Kalpravidh, Phan Q. Minh, M. J. Otte, Vincent Martin, Jan Slingenbergh | ||
| Mapping H5N1 highly pathogenic avian influenza risk in Southeast Asia | |||
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Proc. Natl. Acad. Sci. USA Mar 25, 2008; 105: 4769-4774.
(In "Ecology") |
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| 8. | Amit Agrawal, Rajesh Deo, Geoffrey D. Wang, May D. Wang, Shuming Nie | ||
| Nanometer-scale mapping and single-molecule detection with color-coded nanoparticle probes | |||
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Proc. Natl. Acad. Sci. USA Mar 04, 2008; 105: 3298-3303.
(In "Biophysics") |
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| 9. | Yousin Suh, Gil Atzmon, Mi-Ook Cho, David Hwang, Bingrong Liu, Daniel J. Leahy, Nir Barzilai, Pinchas Cohen | ||
| Functionally significant insulin-like growth factor I receptor mutations in centenarians | |||
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Proc. Natl. Acad. Sci. USA Mar 04, 2008; 105: 3438-3442.
(In "Genetics") |
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| 10. | Deborah S. Rogers, Paul R. Ehrlich | ||
| From the Cover: Natural selection and cultural rates of change | |||
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Proc. Natl. Acad. Sci. USA Mar 04, 2008; 105: 3416-3420.
(In "Evolution") |
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| 11. | Damien A. Fair, Alexander L. Cohen, Nico U. F. Dosenbach, Jessica A. Church, Francis M. Miezin, Deanna M. Barch, Marcus E. Raichle, Steven E. Petersen, Bradley L. Schlaggar | ||
| The maturing architecture of the brain's default network | |||
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Proc. Natl. Acad. Sci. USA Mar 11, 2008; 105: 4028-4032.
(In "Neuroscience") |
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| 12. | J. E. Hirsch | ||
| An index to quantify an individual's scientific research output | |||
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Proc. Natl. Acad. Sci. USA Nov 15, 2005; 102: 16569-16572.
(In "Physics") |
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| 13. | Michael B. Eisen, Paul T. Spellman, Patrick O. Brown, David Botstein | ||
| Cluster analysis and display of genome-wide expression patterns | |||
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Proc. Natl. Acad. Sci. USA Dec 08, 1998; 95: 14863-14868.
(In "Genetics") |
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| 14. | Igor Goychuk, Peter Hänggi | ||
| Ion channel gating: A first-passage time analysis of the Kramers type | |||
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Proc. Natl. Acad. Sci. USA Mar 19, 2002; 99: 3552-3556.
(In "Biophysics") |
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| 15. | Timothy M. Lenton, Hermann Held, Elmar Kriegler, Jim W. Hall, Wolfgang Lucht, Stefan Rahmstorf, Hans Joachim Schellnhuber | ||
| Inaugural Article: Tipping elements in the Earth's climate system | |||
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Proc. Natl. Acad. Sci. USA Feb 12, 2008; 105: 1786-1793.
(In "Sustainability Science-PS") |
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| 16. | David Cesarini, Christopher T. Dawes, James H. Fowler, Magnus Johannesson, Paul Lichtenstein, Björn Wallace | ||
| Heritability of cooperative behavior in the trust game | |||
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Proc. Natl. Acad. Sci. USA Mar 11, 2008; 105: 3721-3726.
(In "Anthropology-BS") |
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| 17. | John F. Nash | ||
| Equilibrium Points in n-Person Games | |||
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Proc. Natl. Acad. Sci. USA Jan 15, 1950; 36: 48-49.
(In "Journal_Article") |
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| 18. | Adrianna C. Jenkins, C. Neil Macrae, Jason P. Mitchell | ||
| From the Cover: Repetition suppression of ventromedial prefrontal activity during judgments of self and others | |||
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Proc. Natl. Acad. Sci. USA Mar 18, 2008; 105: 4507-4512.
(In "Psychology-BS") |
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| 19. | Andrew M. Bellinger, Steven Reiken, Miroslav Dura, Peter W. Murphy, Shi-Xian Deng, Donald W. Landry, David Nieman, Stephan E. Lehnart, Mahendranauth Samaru, Alain LaCampagne, Andrew R. Marks | ||
| Remodeling of ryanodine receptor complex causes "leaky" channels: A molecular mechanism for decreased exercise capacity | |||
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Proc. Natl. Acad. Sci. USA Feb 12, 2008; 105: 2198-2202.
(In "Physiology") |
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| 20. | Katherine M. Thibault, James H. Brown | ||
| Impact of an extreme climatic event on community assembly | |||
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Proc. Natl. Acad. Sci. USA Mar 04, 2008; 105: 3410-3415.
(In "Ecology") |
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| 21. | James Tsai, John T. Lee, Weiru Wang, Jiazhong Zhang, Hanna Cho, Shumeye Mamo, Ryan Bremer, Sam Gillette, Jun Kong, Nikolas K. Haass, Katrin Sproesser, Ling Li, Keiran S. M. Smalley, Daniel Fong, Yong-Liang Zhu, Adhirai Marimuthu, Hoa Nguyen, Billy Lam, Jennifer Liu, Ivana Cheung, Julie Rice, Yoshihisa Suzuki, Catherine Luu, Calvin Settachatgul, Rafe Shellooe, John Cantwell, Sung-Hou Kim, Joseph Schlessinger, Kam Y. J. Zhang, Brian L. West, Ben Powell, Gaston Habets, Chao Zhang, Prabha N. Ibrahim, Peter Hirth, Dean R. Artis, Meenhard Herlyn, Gideon Bollag | ||
| From the Cover: Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity | |||
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Proc. Natl. Acad. Sci. USA Feb 26, 2008; 105: 3041-3046.
(In "Medical Sciences") |
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| 22. | Mathias Ehrich, Julia Turner, Peter Gibbs, Lara Lipton, Mara Giovanneti, Charles Cantor, Dirk van den Boom | ||
| Cytosine methylation profiling of cancer cell lines | |||
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Proc. Natl. Acad. Sci. USA Mar 25, 2008; 105: 4844-4849.
(In "Medical Sciences") |
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| 23. | Daehyun Baek, Phil Green | ||
| Sequence conservation, relative isoform frequencies, and nonsense-mediated decay in evolutionarily conserved alternative splicing | |||
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Proc. Natl. Acad. Sci. USA Aug 25, 2005; doi: 10.1073/pnas.0506139102.
(In "Evolution") |
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| 24. | Monica Uddin, Morris Goodman, Offer Erez, Roberto Romero, Guozhen Liu, Munirul Islam, Juan C. Opazo, Chet C. Sherwood, Lawrence I. Grossman, Derek E. Wildman | ||
| Distinct genomic signatures of adaptation in pre- and postnatal environments during human evolution | |||
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Proc. Natl. Acad. Sci. USA Mar 04, 2008; 105: 3215-3220.
(In "Evolution") |
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| 25. | Ramamurthy Mani, Robert P. St.Onge, John L. Hartman, Guri Giaever, Frederick P. Roth | ||
| Defining genetic interaction | |||
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Proc. Natl. Acad. Sci. USA Mar 04, 2008; 105: 3461-3466.
(In "Genetics") |
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| 26. | Marcus Krüger, Irina Kratchmarova, Blagoy Blagoev, Yu-Hua Tseng, C. Ronald Kahn, Matthias Mann | ||
| Dissection of the insulin signaling pathway via quantitative phosphoproteomics | |||
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Proc. Natl. Acad. Sci. USA Feb 19, 2008; 105: 2451-2456.
(In "Cell Biology") |
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| 27. | Jorge Frias-Lopez, Yanmei Shi, Gene W. Tyson, Maureen L. Coleman, Stephan C. Schuster, Sallie W. Chisholm, Edward F. DeLong | ||
| From the Cover: Microbial community gene expression in ocean surface waters | |||
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Proc. Natl. Acad. Sci. USA Mar 11, 2008; 105: 3805-3810.
(In "Environmental_Sciences-BS") |
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| 28. | David Jackson, Md. Jaber Hossain, Danielle Hickman, Daniel R. Perez, Robert A. Lamb | ||
| A new influenza virus virulence determinant: The NS1 protein four C-terminal residues modulate pathogenicity | |||
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Proc. Natl. Acad. Sci. USA Mar 11, 2008; doi: 10.1073/pnas.0800482105.
(In "Microbiology") |
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| 29. | Francisco J. Ayala | ||
| Science, evolution, and creationism | |||
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Proc. Natl. Acad. Sci. USA Jan 08, 2008; 105: 3-4.
(In "Editorial") |
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| 30. | Carola Holweg, Peter Nick | ||
| Retraction for Holweg and Nick, Arabidopsis myosin XI mutant is defective in organelle movement and polar auxin transport | |||
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Proc. Natl. Acad. Sci. USA Mar 04, 2008; 105: 3658-3658.
(In "Retraction") |
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| 31. | Suling Liu, Christophe Ginestier, Emmanuelle Charafe-Jauffret, Hailey Foco, Celina G. Kleer, Sofia D. Merajver, Gabriela Dontu, Max S. Wicha | ||
| BRCA1 regulates human mammary stem/progenitor cell fate | |||
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Proc. Natl. Acad. Sci. USA Feb 05, 2008; 105: 1680-1685.
(In "Medical Sciences") |
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| 32. | Jenny R. Saffran, Ann Senghas, John C. Trueswell | ||
| The acquisition of language by children | |||
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Proc. Natl. Acad. Sci. USA Nov 06, 2001; 98: 12874-12875.
(In "From The Academy") |
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| 33. | Marios Giannakis, Swaine L. Chen, Sherif M. Karam, Lars Engstrand, Jeffrey I. Gordon | ||
| Helicobacter pylori evolution during progression from chronic atrophic gastritis to gastric cancer and its impact on gastric stem cells | |||
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Proc. Natl. Acad. Sci. USA Mar 10, 2008; doi: 10.1073/pnas.0800668105.
(In "Microbiology") |
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| 34. | M. Elizabeth Halloran, Neil M. Ferguson, Stephen Eubank, Ira M. Longini, Derek A. T. Cummings, Bryan Lewis, Shufu Xu, Christophe Fraser, Anil Vullikanti, Timothy C. Germann, Diane Wagener, Richard Beckman, Kai Kadau, Chris Barrett, Catherine A. Macken, Donald S. Burke, Philip Cooley | ||
| Modeling targeted layered containment of an influenza pandemic in the United States | |||
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Proc. Natl. Acad. Sci. USA Mar 10, 2008; doi: 10.1073/pnas.0706849105.
(In "Environmental_Sciences") |
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| 35. | M. R. Schmer, K. P. Vogel, R. B. Mitchell, R. K. Perrin | ||
| Net energy of cellulosic ethanol from switchgrass | |||
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Proc. Natl. Acad. Sci. USA Jan 15, 2008; 105: 464-469.
(In "Agricultural Sciences") |
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| 36. | Angela C. Poole, Ruth E. Thomas, Laurie A. Andrews, Heidi M. McBride, Alexander J. Whitworth, Leo J. Pallanck | ||
| The PINK1/Parkin pathway regulates mitochondrial morphology | |||
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Proc. Natl. Acad. Sci. USA Feb 05, 2008; 105: 1638-1643.
(In "Genetics") |
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| 37. | Min Li, Baohong Wang, Menghui Zhang, Mattias Rantalainen, Shengyue Wang, Haokui Zhou, Yan Zhang, Jian Shen, Xiaoyan Pang, Meiling Zhang, Hua Wei, Yu Chen, Haifeng Lu, Jian Zuo, Mingming Su, Yunping Qiu, Wei Jia, Chaoni Xiao, Leon M. Smith, Shengli Yang, Elaine Holmes, Huiru Tang, Guoping Zhao, Jeremy K. Nicholson, Lanjuan Li, Liping Zhao | ||
| Symbiotic gut microbes modulate human metabolic phenotypes | |||
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Proc. Natl. Acad. Sci. USA Feb 12, 2008; 105: 2117-2122.
(In "Microbiology") |
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| 38. | Jean William Pape, Paul Farmer, Serena Koenig, Daniel Fitzgerald, Peter Wright, Warren Johnson | ||
| The epidemiology of AIDS in Haiti refutes the claims of Gilbert et al. | |||
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Proc. Natl. Acad. Sci. USA Mar 11, 2008; 105: 13-13.
(In "Letters") |
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| 39. | Madhu S. Kumar, Stefan J. Erkeland, Ryan E. Pester, Cindy Y. Chen, Margaret S. Ebert, Phillip A. Sharp, Tyler Jacks | ||
| Suppression of non-small cell lung tumor development by the let-7 microRNA family | |||
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Proc. Natl. Acad. Sci. USA Mar 11, 2008; 105: 3903-3908.
(In "Medical Sciences") |
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| 40. | Myung Soo Cho, Young-Eun Lee, Ji Young Kim, Seungsoo Chung, Yoon Hee Cho, Dae-Sung Kim, Sang-Moon Kang, Haksup Lee, Myung-Hwa Kim, Jeong-Hoon Kim, Joong Woo Leem, Sun Kyung Oh, Young Min Choi, Dong-Youn Hwang, Jin Woo Chang, Dong-Wook Kim | ||
| Highly efficient and large-scale generation of functional dopamine neurons from human embryonic stem cells | |||
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Proc. Natl. Acad. Sci. USA Mar 04, 2008; 105: 3392-3397.
(In "Developmental Biology") |
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| 41. | Ardian Jusufi, Daniel I. Goldman, Shai Revzen, Robert J. Full | ||
| From the Cover: Active tails enhance arboreal acrobatics in geckos | |||
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Proc. Natl. Acad. Sci. USA Mar 18, 2008; 105: 4215-4219.
(In "Evolution") |
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| 42. | Kalai Mathee, Giri Narasimhan, Camilo Valdes, Xiaoyun Qiu, Jody M. Matewish, Michael Koehrsen, Antonis Rokas, Chandri N. Yandava, Reinhard Engels, Erliang Zeng, Raquel Olavarietta, Melissa Doud, Roger S. Smith, Philip Montgomery, Jared R. White, Paul A. Godfrey, Chinnappa Kodira, Bruce Birren, James E. Galagan, Stephen Lory | ||
| Dynamics of Pseudomonas aeruginosa genome evolution | |||
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Proc. Natl. Acad. Sci. USA Feb 26, 2008; 105: 3100-3105.
(In "Microbiology") |
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| 43. | Raymond E. Goldstein, Idan Tuval, Jan-Willem van de Meent | ||
| From the Cover: Microfluidics of cytoplasmic streaming and its implications for intracellular transport | |||
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Proc. Natl. Acad. Sci. USA Mar 11, 2008; 105: 3663-3667.
(In "Biophysics") |
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| 44. | Anirban Bandyopadhyay, Somobrata Acharya | ||
| A 16-bit parallel processing in a molecular assembly | |||
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Proc. Natl. Acad. Sci. USA Mar 11, 2008; 105: 3668-3672.
(In "Applied Physical Sciences") |
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| 45. | John Damuth | ||
| Scaling of growth: Plants and animals are not so different | |||
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Proc. Natl. Acad. Sci. USA Feb 27, 2001; 98: 2113-2114.
(In "Commentary") |
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| 46. | Cheng Lu, Dong-Hoon Jeong, Karthik Kulkarni, Manoj Pillay, Kan Nobuta, Rana German, Shawn R. Thatcher, Christopher Maher, Lifang Zhang, Doreen Ware, Bin Liu, Xiaofeng Cao, Blake C. Meyers, Pamela J. Green | ||
| Genome-wide analysis for discovery of rice microRNAs reveals natural antisense microRNAs (nat-miRNAs) | |||
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Proc. Natl. Acad. Sci. USA Mar 25, 2008; 105: 4951-4956.
(In "Plant Biology") |
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| 47. | Eric P. Meyer, Alexandra Ulmann-Schuler, Matthias Staufenbiel, Thomas Krucker | ||
| Altered morphology and 3D architecture of brain vasculature in a mouse model for Alzheimer's disease | |||
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Proc. Natl. Acad. Sci. USA Mar 04, 2008; 105: 3587-3592.
(In "Neuroscience") |
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| 48. | Eric Bonabeau | ||
| Agent-based modeling: Methods and techniques for simulating human systems | |||
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Proc. Natl. Acad. Sci. USA May 14, 2002; 99: 7280-7287.
(In "Colloquium") |
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| 49. | Stanley B. Prusiner | ||
| Prions | |||
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Proc. Natl. Acad. Sci. USA Nov 10, 1998; 95: 13363-13383.
(In "Nobel") |
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| 50. | Ailan Guo, Judit Villén, Jon Kornhauser, Kimberly A. Lee, Matthew P. Stokes, Klarisa Rikova, Anthony Possemato, Julie Nardone, Gregory Innocenti, Randall Wetzel, Yi Wang, Joan MacNeill, Jeffrey Mitchell, Steven P. Gygi, John Rush, Roberto D. Polakiewicz, Michael J. Comb | ||
| Signaling networks assembled by oncogenic EGFR and c-Met | |||
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Proc. Natl. Acad. Sci. USA Jan 15, 2008; 105: 692-697.
(In "Medical Sciences") |
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