Most-Read Articles during June 2008 -- updated monthly.

Most-read rankings are recalculated at the beginning of the month and are based on full-text and pdf views.

  1. Biological Sciences - Psychology:
    • Lloyd Kaufman
    • and James H. Kaufman
    From the Cover: Explaining the moon illusionPNAS 2000 97:500-505
  2. Biological Sciences - Genetics:
    • Marina Elez,
    • Miroslav Radman,
    • and Ivan Matic
    The frequency and structure of recombinant products is determined by the cellular level of MutLPNAS 2007 104:8935-8940; published ahead of print May 14, 2007, doi:10.1073/pnas.0610149104
  3. Biological Sciences - Medical Sciences:
    • Dean Ornish,
    • Mark Jesus M. Magbanua,
    • Gerdi Weidner,
    • Vivian Weinberg,
    • Colleen Kemp,
    • Christopher Green,
    • Michael D. Mattie,
    • Ruth Marlin,
    • Jeff Simko,
    • Katsuto Shinohara,
    • Christopher M. Haqq,
    • and Peter R. Carroll
    Changes in prostate gene expression in men undergoing an intensive nutrition and lifestyle interventionPNAS 2008 105:8369-8374; published ahead of print June 16, 2008, doi:10.1073/pnas.0803080105
    Open Access Article
  4. Biological Sciences - Medical Sciences:
    • Kamal E. Habib,
    • Katherine P. Weld,
    • Kenner C. Rice,
    • Judy Pushkas,
    • Maribeth Champoux,
    • Samuel Listwak,
    • Elizabeth L. Webster,
    • Arthur J. Atkinson,
    • Jay Schulkin,
    • Carlo Contoreggi,
    • George P. Chrousos,
    • Samuel M. McCann,
    • Stephen J. Suomi,
    • J. Dee Higley,
    • and Philip W. Gold
    Oral administration of a corticotropin-releasing hormone receptor antagonist significantly attenuates behavioral, neuroendocrine, and autonomic responses to stress in primatesPNAS 2000 97:6079-6084
  5. Reactive Oxygen Species Special Feature - Introduction:
    • Joan Selverstone Valentine
    • and Edith Butler Gralla
    From the Cover: Reactive Oxygen Species Special Feature: Introduction: Reactive Oxygen Species Special FeaturePNAS 2008 105:8178; published ahead of print June 12, 2008, doi:10.1073/pnas.0804252105
  6. Biological Sciences - Neuroscience:
    • Ivanka Savic,
    • Hans Berglund,
    • and Per Lindström
    Brain response to putative pheromones in homosexual menPNAS 2005 102:7356-7361; published ahead of print May 9, 2005, doi:10.1073/pnas.0407998102
  7. Biological Sciences - Psychology:
    • Eiman Azim,
    • Dean Mobbs,
    • Booil Jo,
    • Vinod Menon,
    • and Allan L. Reiss
    Sex differences in brain activation elicited by humorPNAS 2005 102:16496-16501; published ahead of print November 7, 2005, doi:10.1073/pnas.0408456102
  8. Biological Sciences - Genetics:
    • Michael B. Eisen,
    • Paul T. Spellman,
    • Patrick O. Brown,
    • and David Botstein
    Cluster analysis and display of genome-wide expression patternsPNAS 1998 95:14863-14868
  9. Biological Sciences - Cell Biology:
    • Michael Z. Lin,
    • Jeffrey S. Glenn,
    • and Roger Y. Tsien
    From the Cover: A drug-controllable tag for visualizing newly synthesized proteins in cells and whole animalsPNAS 2008 105:7744-7749; published ahead of print May 29, 2008, doi:10.1073/pnas.0803060105
    Open Access Article
  10. Biological Sciences - Evolution:
    • Zachary D. Blount,
    • Christina Z. Borland,
    • and Richard E. Lenski
    Inaugural Article: Historical contingency and the evolution of a key innovation in an experimental population of Escherichia coliPNAS 2008 105:7899-7906; published ahead of print June 4, 2008, doi:10.1073/pnas.0803151105
  11. Neuroscience:
    • Ivanka Savic
    • and Per Lindström
    PET and MRI show differences in cerebral asymmetry and functional connectivity between homo- and heterosexual subjectsPNAS published ahead of print June 16, 2008, doi:10.1073/pnas.0801566105
  12. Biological Sciences - Microbiology:
    • Jessica A. Belser,
    • Ola Blixt,
    • Li-Mei Chen,
    • Claudia Pappas,
    • Taronna R. Maines,
    • Neal Van Hoeven,
    • Ruben Donis,
    • Julia Busch,
    • Ryan McBride,
    • James C. Paulson,
    • Jacqueline M. Katz,
    • and Terrence M. Tumpey
    Contemporary North American influenza H7 viruses possess human receptor specificity: Implications for virus transmissibilityPNAS 2008 105:7558-7563; published ahead of print May 27, 2008, doi:10.1073/pnas.0801259105
    Open Access Article
  13. Mathematics:
    • John F. Nash, Jr.
    Equilibrium Points in N-Person GamesPNAS 1950 36:48-49
  14. Physical Sciences - Environmental Sciences:
    • James Hansen,
    • Makiko Sato,
    • Reto Ruedy,
    • Ken Lo,
    • David W. Lea,
    • and Martin Medina-Elizade
    Global temperature changePNAS 2006 103:14288-14293; published ahead of print September 25, 2006, doi:10.1073/pnas.0606291103
    Open Access Article
  15. Physical Sciences - Physics:
    • J. E. Hirsch
    An index to quantify an individual's scientific research outputPNAS 2005 102:16569-16572; published ahead of print November 7, 2005, doi:10.1073/pnas.0507655102
  16. Biological Sciences - Immunology:
    • Stephan Sauer,
    • Ludovica Bruno,
    • Arnulf Hertweck,
    • David Finlay,
    • Marion Leleu,
    • Mikhail Spivakov,
    • Zachary A. Knight,
    • Bradley S. Cobb,
    • Doreen Cantrell,
    • Eric O'Connor,
    • Kevan M. Shokat,
    • Amanda G. Fisher,
    • and Matthias Merkenschlager
    T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTORPNAS 2008 105:7797-7802; published ahead of print May 28, 2008, doi:10.1073/pnas.0800928105
  17. Letter:
    • John R. Skoyles
    Natural selection does not explain cultural rates of changePNAS 2008 105:E27; published ahead of print May 29, 2008, doi:10.1073/pnas.0802586105
  18. Biological Sciences - Cell Biology:
    • Luis C. Fuentealba,
    • Edward Eivers,
    • Douglas Geissert,
    • Vincent Taelman,
    • and E. M. De Robertis
    Asymmetric mitosis: Unequal segregation of proteins destined for degradationPNAS 2008 105:7732-7737; published ahead of print May 29, 2008, doi:10.1073/pnas.0803027105
    Open Access Article
  19. Biological Sciences - Medical Sciences:
    • Francesco Fornai,
    • Patrizia Longone,
    • Luisa Cafaro,
    • Olga Kastsiuchenka,
    • Michela Ferrucci,
    • Maria Laura Manca,
    • Gloria Lazzeri,
    • Alida Spalloni,
    • Natascia Bellio,
    • Paola Lenzi,
    • Nicola Modugno,
    • Gabriele Siciliano,
    • Ciro Isidoro,
    • Luigi Murri,
    • Stefano Ruggieri,
    • and Antonio Paparelli
    Lithium delays progression of amyotrophic lateral sclerosisPNAS 2008 105:2052-2057; published ahead of print February 4, 2008, doi:10.1073/pnas.0708022105
    Open Access Article
  20. Commentary:
    • David A. Puts,
    • Cynthia L. Jordan,
    • and S. Marc Breedlove
    O brother, where art thou? The fraternal birth-order effect on male sexual orientationPNAS 2006 103:10531-10532; published ahead of print June 30, 2006, doi:10.1073/pnas.0604102103
  21. Commentary:
    • John Damuth
    Scaling of growth: Plants and animals are not so differentPNAS 2001 98:2113-2114; doi:10.1073/pnas.051011198
  22. Biological Sciences - Neuroscience:
    • Antoine Lutz,
    • Lawrence L. Greischar,
    • Nancy B. Rawlings,
    • Matthieu Ricard,
    • and Richard J. Davidson
    Long-term meditators self-induce high-amplitude gamma synchrony during mental practicePNAS 2004 101:16369-16373; published ahead of print November 8, 2004, doi:10.1073/pnas.0407401101
  23. Biological Sciences - Immunology:
    • Douglas C. Palmer,
    • Chi-Chao Chan,
    • Luca Gattinoni,
    • Claudia Wrzesinski,
    • Chrystal M. Paulos,
    • Christian S. Hinrichs,
    • Daniel J. Powell, Jr.,
    • Christopher A. Klebanoff,
    • Steven E. Finkelstein,
    • Robert N. Fariss,
    • Zhiya Yu,
    • Robert B. Nussenblatt,
    • Steven A. Rosenberg,
    • and Nicholas P. Restifo
    From the Cover: Effective tumor treatment targeting a melanoma/melanocyte-associated antigen triggers severe ocular autoimmunityPNAS 2008 105:8061-8066; published ahead of print June 3, 2008, doi:10.1073/pnas.0710929105
    Open Access Article
  24. Biological Sciences - Ecology - Social Sciences - Sustainability Science:
    • Jason Hill,
    • Erik Nelson,
    • David Tilman,
    • Stephen Polasky,
    • and Douglas Tiffany
    From the Cover: Environmental, economic, and energetic costs and benefits of biodiesel and ethanol biofuelsPNAS 2006 103:11206-11210; published ahead of print July 12, 2006, doi:10.1073/pnas.0604600103
  25. Astronomy:
    • Constantino Baikouzis
    • and Marcelo O. Magnasco
    Is an eclipse described in the Odyssey?PNAS published ahead of print June 24, 2008, doi:10.1073/pnas.0803317105
  26. Biological Sciences - Medical Sciences:
    • Chad R. Hancock,
    • Dong-Ho Han,
    • May Chen,
    • Shin Terada,
    • Toshihiro Yasuda,
    • David C. Wright,
    • and John O. Holloszy
    High-fat diets cause insulin resistance despite an increase in muscle mitochondriaPNAS 2008 105:7815-7820; published ahead of print May 28, 2008, doi:10.1073/pnas.0802057105
  27. Biological Sciences - Biophysics:
    • Igor Goychuk
    • and Peter Hänggi
    Ion channel gating: A first-passage time analysis of the Kramers typePNAS 2002 99:3552-3556; published ahead of print March 12, 2002, doi:10.1073/pnas.052015699
  28. From the Academy - U.S. Frontiers Of Science Symposium:
    • Jenny R. Saffran,
    • Ann Senghas,
    • and John C. Trueswell
    From the Academy: The acquisition of language by childrenPNAS 2001 98:12874-12875; published ahead of print October 30, 2001, doi:10.1073/pnas.231498898
  29. Biological Sciences - Microbiology:
    • Mark C. Enright,
    • D. Ashley Robinson,
    • Gaynor Randle,
    • Edward J. Feil,
    • Hajo Grundmann,
    • and Brian G. Spratt
    The evolutionary history of methicillin-resistant Staphylococcus aureus (MRSA)PNAS 2002 99:7687-7692; published ahead of print May 21, 2002, doi:10.1073/pnas.122108599
  30. Physical Sciences - Applied Physical Sciences:
    • Kwang-Il Goh,
    • Michael E. Cusick,
    • David Valle,
    • Barton Childs,
    • Marc Vidal,
    • and Albert-László Barabási
    The human disease networkPNAS 2007 104:8685-8690; published ahead of print May 14, 2007, doi:10.1073/pnas.0701361104
  31. Commentary:
    • Edward W. Kraegen,
    • Gregory J. Cooney,
    • and Nigel Turner
    Muscle insulin resistance: A case of fat overconsumption, not mitochondrial dysfunctionPNAS 2008 105:7627-7628; published ahead of print May 28, 2008, doi:10.1073/pnas.0803901105
  32. Biological Sciences - Evolution:
    • M. Thomas P. Gilbert,
    • Daniela I. Drautz,
    • Arthur M. Lesk,
    • Simon Y. W. Ho,
    • Ji Qi,
    • Aakrosh Ratan,
    • Chih-Hao Hsu,
    • Andrei Sher,
    • Love Dalén,
    • Anders Götherström,
    • Lynn P. Tomsho,
    • Snjezana Rendulic,
    • Michael Packard,
    • Paula F. Campos,
    • Tatyana V. Kuznetsova,
    • Fyodor Shidlovskiy,
    • Alexei Tikhonov,
    • Eske Willerslev,
    • Paola Iacumin,
    • Bernard Buigues,
    • Per G. P. Ericson,
    • Mietje Germonpré,
    • Pavel Kosintsev,
    • Vladimir Nikolaev,
    • Malgosia Nowak-Kemp,
    • James R. Knight,
    • Gerard P. Irzyk,
    • Clotilde S. Perbost,
    • Karin M. Fredrikson,
    • Timothy T. Harkins,
    • Sharon Sheridan,
    • Webb Miller,
    • and Stephan C. Schuster
    Intraspecific phylogenetic analysis of Siberian woolly mammoths using complete mitochondrial genomesPNAS 2008 105:8327-8332; published ahead of print June 9, 2008, doi:10.1073/pnas.0802315105
    Open Access Article
  33. Correction:
    • Randy Schekman
    Editorial Expression of Concern for multiple articlesPNAS 2008 105:7893; published ahead of print May 19, 2008, doi:10.1073/pnas.0803890105
  34. Biological Sciences - Pharmacology:
    • José A. Matta,
    • Paul M. Cornett,
    • Rosa L. Miyares,
    • Ken Abe,
    • Niaz Sahibzada,
    • and Gerard P. Ahern
    From the Cover: General anesthetics activate a nociceptive ion channel to enhance pain and inflammationPNAS 2008 105:8784-8789; published ahead of print June 23, 2008, doi:10.1073/pnas.0711038105
  35. Biological Sciences - Cell Biology:
    • Susanna Purhonen,
    • Jarmo Palm,
    • Derrick Rossi,
    • Nina Kaskenpää,
    • Iiro Rajantie,
    • Seppo Ylä-Herttuala,
    • Kari Alitalo,
    • Irving L. Weissman,
    • and Petri Salven
    Bone marrow-derived circulating endothelial precursors do not contribute to vascular endothelium and are not needed for tumor growthPNAS 2008 105:6620-6625; published ahead of print April 28, 2008, doi:10.1073/pnas.0710516105
    Open Access Article
  36. Biological Sciences - Microbiology:
    • Regis Gomes,
    • Clarissa Teixeira,
    • Maria Jânia Teixeira,
    • Fabiano Oliveira,
    • Maria José Menezes,
    • Claire Silva,
    • Camila I. de Oliveira,
    • Jose C. Miranda,
    • Dia-Eldin Elnaiem,
    • Shaden Kamhawi,
    • Jesus G. Valenzuela,
    • and Cláudia I. Brodskyn
    Immunity to a salivary protein of a sand fly vector protects against the fatal outcome of visceral leishmaniasis in a hamster modelPNAS 2008 105:7845-7850; published ahead of print May 28, 2008, doi:10.1073/pnas.0712153105
    Open Access Article
  37. Biological Sciences - Anthropology:
    • Janet M. Wilmshurst,
    • Atholl J. Anderson,
    • Thomas F. G. Higham,
    • and Trevor H. Worthy
    Dating the late prehistoric dispersal of Polynesians to New Zealand using the commensal Pacific ratPNAS 2008 105:7676-7680; published ahead of print June 3, 2008, doi:10.1073/pnas.0801507105
    Open Access Article
  38. Biological Sciences - Genetics:
    • Karen A. Boehme,
    • Roman Kulikov,
    • and Christine Blattner
    p53 stabilization in response to DNA damage requires Akt/PKB and DNA-PKPNAS 2008 105:7785-7790; published ahead of print May 27, 2008, doi:10.1073/pnas.0703423105
  39. Biological Sciences - Medical Sciences:
    • Marius Wernig,
    • Jian-Ping Zhao,
    • Jan Pruszak,
    • Eva Hedlund,
    • Dongdong Fu,
    • Frank Soldner,
    • Vania Broccoli,
    • Martha Constantine-Paton,
    • Ole Isacson,
    • and Rudolf Jaenisch
    Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's diseasePNAS 2008 105:5856-5861; published ahead of print April 7, 2008, doi:10.1073/pnas.0801677105
  40. Biological Sciences - Genetics:
    • Kirill A. Datsenko
    • and Barry L. Wanner
    One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR productsPNAS 2000 97:6640-6645; published ahead of print May 30, 2000
  41. Physical Sciences - Statistics:
    • Hans-Georg Müller,
    • Ian Abramson,
    • and Rahman Azari
    Nonparametric regression to the meanPNAS 2003 100:9715-9720; published ahead of print August 5, 2003, doi:10.1073/pnas.1733547100
  42. Physical Sciences - Chemistry - Biological Sciences - Biophysics:
    • Giorgio Colombo,
    • Giulia Morra,
    • Massimiliano Meli,
    • and Gennady Verkhivker
    Understanding ligand-based modulation of the Hsp90 molecular chaperone dynamics at atomic resolutionPNAS 2008 105:7976-7981; published ahead of print May 29, 2008, doi:10.1073/pnas.0802879105
    Open Access Article
  43. Biological Sciences - Cell Biology:
    • W. E. Lowry,
    • L. Richter,
    • R. Yachechko,
    • A. D. Pyle,
    • J. Tchieu,
    • R. Sridharan,
    • A. T. Clark,
    • and K. Plath
    Generation of human induced pluripotent stem cells from dermal fibroblastsPNAS 2008 105:2883-2888; published ahead of print February 15, 2008, doi:10.1073/pnas.0711983105
  44. Biological Sciences - Biochemistry:
    • Asuka Azuma-Mukai,
    • Hideo Oguri,
    • Toutai Mituyama,
    • Zhi Rong Qian,
    • Kiyoshi Asai,
    • Haruhiko Siomi,
    • and Mikiko C. Siomi
    Characterization of endogenous human Argonautes and their miRNA partners in RNA silencingPNAS 2008 105:7964-7969; published ahead of print June 4, 2008, doi:10.1073/pnas.0800334105
  45. Reactive Oxygen Species Special Feature - Research Articles - Biological Sciences - Medical Sciences:
    • Lizzia Raffaghello,
    • Changhan Lee,
    • Fernando M. Safdie,
    • Min Wei,
    • Federica Madia,
    • Giovanna Bianchi,
    • and Valter D. Longo
    From the Cover: Reactive Oxygen Species Special Feature: Starvation-dependent differential stress resistance protects normal but not cancer cells against high-dose chemotherapyPNAS 2008 105:8215-8220; published ahead of print March 31, 2008, doi:10.1073/pnas.0708100105
  46. Biological Sciences - Genetics:
    • Lin Zhang,
    • Stefano Volinia,
    • Tomas Bonome,
    • George Adrian Calin,
    • Joel Greshock,
    • Nuo Yang,
    • Chang-Gong Liu,
    • Antonis Giannakakis,
    • Pangiotis Alexiou,
    • Kosei Hasegawa,
    • Cameron N. Johnstone,
    • Molly S. Megraw,
    • Sarah Adams,
    • Heini Lassus,
    • Jia Huang,
    • Sippy Kaur,
    • Shun Liang,
    • Praveen Sethupathy,
    • Arto Leminen,
    • Victor A. Simossis,
    • Raphael Sandaltzopoulos,
    • Yoshio Naomoto,
    • Dionyssios Katsaros,
    • Phyllis A. Gimotty,
    • Angela DeMichele,
    • Qihong Huang,
    • Ralf Bützow,
    • Anil K. Rustgi,
    • Barbara L. Weber,
    • Michael J. Birrer,
    • Artemis G. Hatzigeorgiou,
    • Carlo M. Croce,
    • and George Coukos
    Genomic and epigenetic alterations deregulate microRNA expression in human epithelial ovarian cancerPNAS 2008 105:7004-7009; published ahead of print May 5, 2008, doi:10.1073/pnas.0801615105
  47. Biological Sciences - Medical Sciences:
    • Brandon F. Keele,
    • Elena E. Giorgi,
    • Jesus F. Salazar-Gonzalez,
    • Julie M. Decker,
    • Kimmy T. Pham,
    • Maria G. Salazar,
    • Chuanxi Sun,
    • Truman Grayson,
    • Shuyi Wang,
    • Hui Li,
    • Xiping Wei,
    • Chunlai Jiang,
    • Jennifer L. Kirchherr,
    • Feng Gao,
    • Jeffery A. Anderson,
    • Li-Hua Ping,
    • Ronald Swanstrom,
    • Georgia D. Tomaras,
    • William A. Blattner,
    • Paul A. Goepfert,
    • J. Michael Kilby,
    • Michael S. Saag,
    • Eric L. Delwart,
    • Michael P. Busch,
    • Myron S. Cohen,
    • David C. Montefiori,
    • Barton F. Haynes,
    • Brian Gaschen,
    • Gayathri S. Athreya,
    • Ha Y. Lee,
    • Natasha Wood,
    • Cathal Seoighe,
    • Alan S. Perelson,
    • Tanmoy Bhattacharya,
    • Bette T. Korber,
    • Beatrice H. Hahn,
    • and George M. Shaw
    Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infectionPNAS 2008 105:7552-7557; published ahead of print May 19, 2008, doi:10.1073/pnas.0802203105
    Open Access Article
  48. Biological Sciences - Medical Sciences:
    • Li Zhong,
    • Baozheng Li,
    • Cathryn S. Mah,
    • Lakshmanan Govindasamy,
    • Mavis Agbandje-McKenna,
    • Mario Cooper,
    • Roland W. Herzog,
    • Irene Zolotukhin,
    • Kenneth H. Warrington, Jr.,
    • Kirsten A. Weigel-Van Aken,
    • Jacqueline A. Hobbs,
    • Sergei Zolotukhin,
    • Nicholas Muzyczka,
    • and Arun Srivastava
    Next generation of adeno-associated virus 2 vectors: Point mutations in tyrosines lead to high-efficiency transduction at lower dosesPNAS 2008 105:7827-7832; published ahead of print May 29, 2008, doi:10.1073/pnas.0802866105
    Open Access Article
  49. Physical Sciences - Engineering - Biological Sciences - Immunology:
    • Keyue Shen,
    • V. Kaye Thomas,
    • Michael L. Dustin,
    • and Lance C. Kam
    From the Cover: Micropatterning of costimulatory ligands enhances CD4 + T cell functionPNAS 2008 105:7791-7796; published ahead of print May 27, 2008, doi:10.1073/pnas.0710295105
  50. Biological Sciences - Neuroscience:
    • Mala M. Shah,
    • Michele Migliore,
    • Ignacio Valencia,
    • Edward C. Cooper,
    • and David A. Brown
    Functional significance of axonal Kv7 channels in hippocampal pyramidal neuronsPNAS 2008 105:7869-7874; published ahead of print May 30, 2008, doi:10.1073/pnas.0802805105
    Open Access Article

Last updated 07/09/2008 13:13:47

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