Skip to main content
  • Submit
  • About
    • Editorial Board
    • PNAS Staff
    • FAQ
    • Accessibility Statement
    • Rights and Permissions
    • Site Map
  • Contact
  • Journal Club
  • Subscribe
    • Subscription Rates
    • Subscriptions FAQ
    • Open Access
    • Recommend PNAS to Your Librarian
  • Log in
  • My Cart

Main menu

  • Home
  • Articles
    • Current
    • Special Feature Articles - Most Recent
    • Special Features
    • Colloquia
    • Collected Articles
    • PNAS Classics
    • List of Issues
  • Front Matter
  • News
    • For the Press
    • This Week In PNAS
    • PNAS in the News
  • Podcasts
  • Authors
    • Information for Authors
    • Editorial and Journal Policies
    • Submission Procedures
    • Fees and Licenses
  • Submit
  • About
    • Editorial Board
    • PNAS Staff
    • FAQ
    • Accessibility Statement
    • Rights and Permissions
    • Site Map
  • Contact
  • Journal Club
  • Subscribe
    • Subscription Rates
    • Subscriptions FAQ
    • Open Access
    • Recommend PNAS to Your Librarian

User menu

  • Log in
  • My Cart

Search

  • Advanced search
Home
Home

Advanced Search

  • Home
  • Articles
    • Current
    • Special Feature Articles - Most Recent
    • Special Features
    • Colloquia
    • Collected Articles
    • PNAS Classics
    • List of Issues
  • Front Matter
  • News
    • For the Press
    • This Week In PNAS
    • PNAS in the News
  • Podcasts
  • Authors
    • Information for Authors
    • Editorial and Journal Policies
    • Submission Procedures
    • Fees and Licenses

New Research In

Physical Sciences

Featured Portals

  • Physics
  • Chemistry
  • Sustainability Science

Articles by Topic

  • Applied Mathematics
  • Applied Physical Sciences
  • Astronomy
  • Computer Sciences
  • Earth, Atmospheric, and Planetary Sciences
  • Engineering
  • Environmental Sciences
  • Mathematics
  • Statistics

Social Sciences

Featured Portals

  • Anthropology
  • Sustainability Science

Articles by Topic

  • Economic Sciences
  • Environmental Sciences
  • Political Sciences
  • Psychological and Cognitive Sciences
  • Social Sciences

Biological Sciences

Featured Portals

  • Sustainability Science

Articles by Topic

  • Agricultural Sciences
  • Anthropology
  • Applied Biological Sciences
  • Biochemistry
  • Biophysics and Computational Biology
  • Cell Biology
  • Developmental Biology
  • Ecology
  • Environmental Sciences
  • Evolution
  • Genetics
  • Immunology and Inflammation
  • Medical Sciences
  • Microbiology
  • Neuroscience
  • Pharmacology
  • Physiology
  • Plant Biology
  • Population Biology
  • Psychological and Cognitive Sciences
  • Sustainability Science
  • Systems Biology
Research Article

Overexpression of LMO4 induces mammary hyperplasia, promotes cell invasion, and is a predictor of poor outcome in breast cancer

Eleanor Y. M. Sum, Davendra Segara, Belinda Duscio, Mary L. Bath, Andrew S. Field, Robert L. Sutherland, Geoffrey J. Lindeman, and Jane E. Visvader
PNAS May 24, 2005 102 (21) 7659-7664; https://doi.org/10.1073/pnas.0502990102
Eleanor Y. M. Sum
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Davendra Segara
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Belinda Duscio
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Mary L. Bath
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Andrew S. Field
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Robert L. Sutherland
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Geoffrey J. Lindeman
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Jane E. Visvader
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  1. Communicated by Suzanne Cory, The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia, April 12, 2005 (received for review November 23, 2004)

  • Article
  • Figures & SI
  • Info & Metrics
  • PDF
Loading

Online Impact

 

Article Information

vol. 102 no. 21 7659-7664
DOI: 
https://doi.org/10.1073/pnas.0502990102
PubMed: 
15897450

Published By: 
National Academy of Sciences
Print ISSN: 
0027-8424
Online ISSN: 
1091-6490
History: 
  • Published in issue May 24, 2005.
  • Published first May 16, 2005.

Copyright & Usage: 
Copyright © 2005, The National Academy of Sciences

Author Information

  1. Eleanor Y. M. Sum *,
  2. Davendra Segara †,
  3. Belinda Duscio *,
  4. Mary L. Bath *,
  5. Andrew S. Field ‡,
  6. Robert L. Sutherland †,
  7. Geoffrey J. Lindeman *, and
  8. Jane E. Visvader * , §
  1. *The Walter and Eliza Hall Institute of Medical Research and Bone Marrow Research Laboratories, 1G Royal Parade, Parkville VIC 3050, Australia; †Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst NSW 2010, Australia; and ‡Department of Anatomical Pathology, St. Vincent's Hospital, Darlinghurst NSW 2010, Australia
  1. Communicated by Suzanne Cory, The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia, April 12, 2005 (received for review November 23, 2004)

Footnotes

  • ↵ § To whom correspondence should be addressed. E-mail: visvader{at}wehi.edu.au.

  • Author contributions: E.Y.M.S., G.J.L., and J.E.V. designed research; E.Y.M.S., D.S., B.D., A.S.F., R.L.S., G.J.L., and J.E.V. performed research; E.Y.M.S., D.S., A.S.F., R.L.S., G.J.L., and J.E.V. analyzed data; M.L.B. contributed new reagents/analytic tools; and J.E.V. wrote the paper.

  • Abbreviations: siRNA, small interfering RNA; LMO, LIM-only; RNAi, RNA interference; MMTV, mouse mammary tumor virus; MIN, mammary intraepithelial neoplasia; HR, hazard ratio; CI, confidence interval; ER, estrogen receptor; PR, progesterone receptor.

  • Copyright © 2005, The National Academy of Sciences

Cited By...

  • 70 Citations
  • 61 Citations
  • Google Scholar

This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

  • Transcriptome analyses of mouse and human mammary cell subpopulations reveal multiple conserved genes and pathways
    Elgene Lim, Di Wu, Bhupinder Pal, Toula Bouras, Marie-Liesse Asselin-Labat, François Vaillant, Hideo Yagita, Geoffrey J Lindeman, Gordon K Smyth, Jane E Visvader
    Breast Cancer Research 2010 12 2
  • Androgen Receptor Inhibits Estrogen Receptor-α Activity and Is Prognostic in Breast Cancer
    Amelia A. Peters, Grant Buchanan, Carmela Ricciardelli, Tina Bianco-Miotto, Margaret M. Centenera, Jonathan M. Harris, Shalini Jindal, Davendra Segara, Li Jia, Nicole L. Moore, Susan M. Henshall, Stephen N. Birrell, Gerhard A. Coetzee, Robert L. Sutherland, Lisa M. Butler, Wayne D. Tilley
    Cancer Research 2009 69 15
  • Discovery of novel mechanosensitive genes in vivo using mouse carotid artery endothelium exposed to disturbed flow
    Chih-Wen Ni, Haiwei Qiu, Amir Rezvan, Kihwan Kwon, Douglas Nam, Dong Ju Son, Jane E. Visvader, Hanjoong Jo
    Blood 2010 116 15
  • LIM-domain-only proteins in cancer
    Jacqueline M. Matthews, Krystal Lester, Soumya Joseph, David J. Curtis
    Nature Reviews Cancer 2013 13 2
  • Identification of a multi-cancer gene expression biomarker for cancer clinical outcomes using a network-based algorithm
    Emmanuel Martinez-Ledesma, Roeland G.W. Verhaak, Victor Treviño
    Scientific Reports 2015 5 1
  • Negative Regulation of Estrogen Receptor α Transactivation Functions by LIM Domain Only 4 Protein
    Rajesh R. Singh, Christopher J. Barnes, Amjad H. Talukder, Suzanne A.W. Fuqua, Rakesh Kumar
    Cancer Research 2005 65 22
  • The oncoprotein HBXIP activates transcriptional coregulatory protein LMO4 via Sp1 to promote proliferation of breast cancer cells
    Lin Yue, Leilei Li, Fangfang Liu, Nan Hu, Weiying Zhang, Xiao Bai, Yinghui Li, Yingyi Zhang, Li Fu, Xiaodong Zhang, Lihong Ye
    Carcinogenesis 2013 34 4
  • c-Myc overexpression and endocrine resistance in breast cancer
    Catriona M. McNeil, C. Marcelo Sergio, Luke R. Anderson, Claire K. Inman, Sarah A. Eggleton, Niamh C. Murphy, Ewan K.A. Millar, Paul Crea, James G. Kench, M. Chehani Alles, Margaret Gardiner-Garden, Christopher J. Ormandy, Alison J. Butt, Susan M. Henshall, Elizabeth A. Musgrove, Robert L. Sutherland
    The Journal of Steroid Biochemistry and Molecular Biology 2006 102 1-5
  • The LIM-only factor LMO4 regulates expression of the BMP7 gene through an HDAC2-dependent mechanism, and controls cell proliferation and apoptosis of mammary epithelial cells
    N Wang, K K Lin, Z Lu, K S Lam, R Newton, X Xu, Z Yu, G N Gill, B Andersen
    Oncogene 2007 26 44
  • Differential expression profiling analyses identifies downregulation of 1p, 6q, and 14q genes and overexpression of 6p histone cluster 1 genes as markers of recurrence in meningiomas
    Elisa Pérez-Magán, Ángel Rodríguez de Lope, Teresa Ribalta, Yolanda Ruano, Yolanda Campos-Martín, Gerardo Pérez-Bautista, Juan Fernando García, Ainoha García-Claver, Concepción Fiaño, José-Luis Hernández-Moneo, Manuela Mollejo, Bárbara Meléndez
    Neuro-Oncology 2010 12 12
  • Drosophila, a genetic model system to study cocaine-related behaviors: A review with focus on LIM-only proteins
    Ulrike Heberlein, Linus T.-Y. Tsai, David Kapfhamer, Amy W. Lasek
    Neuropharmacology 2009 56
  • The Previously Undescribed ZKSCAN3 (ZNF306) Is a Novel “Driver” of Colorectal Cancer Progression
    Lin Yang, Stanley R. Hamilton, Anil Sood, Toshio Kuwai, Lee Ellis, Angela Sanguino, Gabriel Lopez-Berestein, Douglas D. Boyd
    Cancer Research 2008 68 11
  • Grhl3 and Lmo4 play coordinate roles in epidermal migration
    Nikki R. Hislop, Jacinta Caddy, Stephen B. Ting, Alana Auden, Sumitha Vasudevan, Sarah L. King, Geoffrey J. Lindeman, Jane E. Visvader, John M. Cunningham, Stephen M. Jane
    Developmental Biology 2008 321 1
  • LMO4 is an essential mediator of ErbB2/HER2/Neu-induced breast cancer cell cycle progression
    M E Montañez-Wiscovich, D D Seachrist, M D Landis, J Visvader, B Andersen, R A Keri
    Oncogene 2009 28 41
  • Marginal Maternal Zinc Deficiency in Lactating Mice Reduces Secretory Capacity and Alters Milk Composition
    Colleen Dempsey, Nicholas H. McCormick, Thomas P. Croxford, Young Ah Seo, Arthur Grider, Shannon L. Kelleher
    The Journal of Nutrition 2012 142 4
  • Mutation analysis of FANCD2, BRIP1/BACH1, LMO4 and SFN in familial breast cancer
    Aaron G Lewis, James Flanagan, Anna Marsh, Gulietta M Pupo, Graham Mann, Amanda B Spurdle, Geoffrey J Lindeman, Jane E Visvader, Melissa A Brown, Georgia Chenevix-Trench
    Breast Cancer Research 2005 7 6
  • Rab11a Differentially Modulates Epidermal Growth Factor-induced Proliferation and Motility in Immortal Breast Cells
    Diane Palmieri, Amina Bouadis, Ruban Ronchetti, Maria J. Merino, Patricia S. Steeg
    Breast Cancer Research and Treatment 2006 100 2
  • LMO2 Is a Novel Predictive Marker for a Better Prognosis in Pancreatic Cancer
    Kohei Nakata, Kenoki Ohuchida, Eishi Nagai, Akifumi Hayashi, Yoshihiro Miyasaka, Tadashi Kayashima, Jun Yu, Shinichi Aishima, Yoshinao Oda, Kazuhiro Mizumoto, Masao Tanaka, Masazumi Tsuneyoshi
    Neoplasia 2009 11 7
  • LMO3 interacts with p53 and inhibits its transcriptional activity
    Steven Larsen, Tomoki Yokochi, Eriko Isogai, Yohko Nakamura, Toshinori Ozaki, Akira Nakagawara
    Biochemical and Biophysical Research Communications 2010 392 3
  • Oncogenic LMO3 Collaborates with HEN2 to Enhance Neuroblastoma Cell Growth through Transactivation of Mash1
    Eriko Isogai, Miki Ohira, Toshinori Ozaki, Shigeyuki Oba, Yohko Nakamura, Akira Nakagawara, Laszlo Tora
    PLoS ONE 2011 6 5
  • Mouse Mammary Tumor Virus p75 and p110 CUX1 Transgenic Mice Develop Mammary Tumors of Various Histologic Types
    Chantal Cadieux, Valérie Kedinger, Lu Yao, Charles Vadnais, Maria Drossos, Marilène Paquet, Alain Nepveu
    Cancer Research 2009 69 18
  • Requirement for Lmo4 in the vestibular morphogenesis of mouse inner ear
    Min Deng, Ling Pan, Xiaoling Xie, Lin Gan
    Developmental Biology 2010 338 1
  • Unbiased Screening for Transcriptional Targets of ZKSCAN3 Identifies Integrin β4 and Vascular Endothelial Growth Factor as Downstream Targets
    Lin Yang, Li Zhang, Qiuyu Wu, Douglas D. Boyd
    Journal of Biological Chemistry 2008 283 50
  • Lmo4 in the nucleus accumbens regulates cocaine sensitivity
    A. W. Lasek, D. Kapfhamer, V. Kharazia, J. Gesch, F. Giorgetti, U. Heberlein
    Genes, Brain and Behavior 2010 9 7
  • Expression of LMO4 and outcome in pancreatic ductal adenocarcinoma
    N C Murphy, C J Scarlett, J G Kench, E Y M Sum, D Segara, E K Colvin, J Susanto, P H Cosman, C-S Lee, E A Musgrove, R L Sutherland, G J Lindeman, S M Henshall, J E Visvader, A V Biankin
    British Journal of Cancer 2008 98 3
  • Contribution of DEAF1 Structural Domains to the Interaction with the Breast Cancer Oncogene LMO4
    Liza Cubeddu, Soumya Joseph, Derek J. Richard, Jacqueline M. Matthews, Bin Xue
    PLoS ONE 2012 7 6
  • SSBP2 is an in vivo tumor suppressor and regulator of LDB1 stability
    Y Wang, S Klumpp, H M Amin, H Liang, J Li, Z Estrov, P Zweidler-McKay, S J Brandt, A Agulnick, L Nagarajan
    Oncogene 2010 29 21
  • LIM-domain-only proteins: multifunctional nuclear transcription coregulators that interacts with diverse proteins
    Meixiang Sang, Li Ma, Meijie Sang, Xinliang Zhou, Wei Gao, Cuizhi Geng
    Molecular Biology Reports 2014 41 2
  • Tyrosine Phosphatase Shp2 Mediates the Estrogen Biological Action in Breast Cancer via Interaction with the Estrogen Extranuclear Receptor
    Jun Li, Yujia Kang, Longgang Wei, Wenjie Liu, Yingpu Tian, Baozhen Chen, Xiandong Lin, Yang Li, Gen-Sheng Feng, Zhongxian Lu, Haibin Wang
    PLoS ONE 2014 9 7
  • Aberrant expression of LMO4 induces centrosome amplification and mitotic spindle abnormalities in breast cancer cells
    Marjorie E Montañez-Wiscovich, Melissa D Shelton, Darcie D Seachrist, Kristen L Lozada, Emhonta Johnson, John D Miedler, Fadi W Abdul-Karim, Jane E Visvader, Ruth A Keri
    The Journal of Pathology 2010 222 3
  • LIM domain only 4 protein promotes granulocyte colony-stimulating factor-induced signaling in neurons
    Mariana Gomez-Smith, Zhaohong Qin, Xun Zhou, Sarah C. Schock, Hsiao-Huei Chen
    Cellular and Molecular Life Sciences 2010 67 6
  • Repression of Lim only protein 4-activated transcription inhibits proliferation and induces apoptosis of normal mammary epithelial cells and breast cancer cells
    Yingpu Tian, Ning Wang, Zhongxian Lu
    Clinical & Experimental Metastasis 2010 27 7
  • LMO3 promotes hepatocellular carcinoma invasion, metastasis and anoikis inhibition by directly interacting with LATS1 and suppressing Hippo signaling
    Yang Cheng, Tianlu Hou, Jian Ping, Tianyang Chen, Baobing Yin
    Journal of Experimental & Clinical Cancer Research 2018 37 1
  • The Co-factor of LIM Domains (CLIM/LDB/NLI) Maintains Basal Mammary Epithelial Stem Cells and Promotes Breast Tumorigenesis
    Michael L. Salmans, Zhengquan Yu, Kazuhide Watanabe, Eric Cam, Peng Sun, Padhraic Smyth, Xing Dai, Bogi Andersen, Kent W. Hunter
    PLoS Genetics 2014 10 7
  • LMO4 inhibits p53-mediated proliferative inhibition of breast cancer cells through interacting p53
    Xinliang Zhou, Meixiang Sang, Wei Liu, Wei Gao, Enhong Xing, Weihua Lü, Yingying Xu, Xiaojie Fan, Shaowu Jing, Baoen Shan
    Life Sciences 2012 91 9-10
  • The Structure of an LIM-Only Protein 4 (LMO4) and Deformed Epidermal Autoregulatory Factor-1 (DEAF1) Complex Reveals a Common Mode of Binding to LMO4
    Soumya Joseph, Ann H. Kwan, Philippa H. Stokes, Joel P. Mackay, Liza Cubeddu, Jacqueline M. Matthews, Ann Dean
    PLoS ONE 2014 9 10
  • Apoptotic Cell Death in Neuroblastoma
    Yuanyuan Li, Akira Nakagawara
    Cells 2013 2 2
  • Chromatin interactome mapping at 139 independent breast cancer risk signals
    Jonathan Beesley, Haran Sivakumaran, Mahdi Moradi Marjaneh, Luize G. Lima, Kristine M. Hillman, Susanne Kaufmann, Natasha Tuano, Nehal Hussein, Sunyoung Ham, Pamela Mukhopadhyay, Stephen Kazakoff, Jason S. Lee, Kyriaki Michailidou, Daniel R. Barnes, Antonis C. Antoniou, Laura Fachal, Alison M. Dunning, Douglas F. Easton, Nicola Waddell, Joseph Rosenbluh, Andreas Möller, Georgia Chenevix-Trench, Juliet D. French, Stacey L. Edwards
    Genome Biology 2020 21 1
  • Epitope Tagging of Proteins at the Native Chromosomal Loci of Genes in Mice and in Cultured Vertebrate Cells
    Yen-I G. Chen, Shanna D. Maika, Scott W. Stevens
    Journal of Molecular Biology 2006 361 3
  • Drosophila LIM-Only Is a Positive Regulator of Transcription During Thoracic Bristle Development
    Shamir Zenvirt, Yael Nevo-Caspi, Sigal Rencus-Lazar, Daniel Segal
    Genetics 2008 179 4
  • LMO4 modulates proliferation and differentiation of 3T3-L1 preadipocytes
    Ning Wang, Xichen Wang, Mingxin Shi, Hongyan Shi, Xiaohong Yan, Hui Li, Shouzhi Wang, Yuxiang Wang
    FEBS Letters 2013 587 18
  • Necdin, a p53-Target Gene, Is an Inhibitor of p53-Mediated Growth Arrest
    Julie Lafontaine, Francis Rodier, Véronique Ouellet, Anne-Marie Mes-Masson, Mikhail V. Blagosklonny
    PLoS ONE 2012 7 2
  • LMO4 expression in squamous cell carcinoma of the anterior tongue
    Rhonda A Kwong, Christopher J Scarlett, Larry H Kalish, Ian E Cole, James G Kench, Eleanor YM Sum, Elizabeth A Musgrove, Susan M Henshall, Geoffrey J Lindeman, Andrew V Biankin, Jane E Visvader, Robert L Sutherland
    Histopathology 2011 58 3
  • Structural Basis of the Interaction of the Breast Cancer Oncogene LMO4 with the Tumour Suppressor CtIP/RBBP8
    P.H. Stokes, C.W. Liew, A.H. Kwan, P. Foo, H.E. Barker, A. Djamirze, V. O'Reilly, J.E. Visvader, J.P. Mackay, J.M. Matthews
    Journal of Molecular Biology 2013 425 7
  • LIM-Only Protein 4 (LMO4) and LIM Domain Binding Protein 1 (LDB1) Promote Growth and Metastasis of Human Head and Neck Cancer (LMO4 and LDB1 in Head and Neck Cancer)
    Elizabeth A. Simonik, Ying Cai, Katherine N. Kimmelshue, Dana M. Brantley-Sieders, Holli A. Loomans, Claudia D. Andl, Grant M. Westlake, Victoria M. Youngblood, Jin Chen, Wendell G. Yarbrough, Brandee T. Brown, Lalitha Nagarajan, Stephen J. Brandt, Gautam Sethi
    PLOS ONE 2016 11 10
  • The LIM-domain only protein 4 contributes to lung epithelial cell proliferation but is not essential for tumor progression
    Aliaksei Z. Holik, Caitlin E. Filby, Julie Pasquet, Kati Viitaniemi, John Ciciulla, Kate D. Sutherland, Marie-Liesse Asselin-Labat
    Respiratory Research 2015 16 1
  • 1H, 15N and 13C assignments of an intramolecular LMO4-LIM1/CtIP complex
    Chu Wai Liew, Ann H. Kwan, Philippa H. Stokes, Joel P. Mackay, Jacqueline M. Matthews
    Biomolecular NMR Assignments 2012 6 1
  • Backbone and side-chain assignments of a tethered complex between LMO4 and DEAF-1
    Soumya Joseph, Ann H. Y. Kwan, Joel P. Mackay, Liza Cubeddu, Jacqueline M. Matthews
    Biomolecular NMR Assignments 2014 8 1
  • CRISPR/Cas9‐mediated knockout of Lim‐domain only four retards organ of Corti cell growth
    Rajamani Rathinam, Rita Rosati, Samson Jamesdaniel
    Journal of Cellular Biochemistry 2018 119 4
  • Dietary zinc deficiency or supplementation during gestation increases breast cancer susceptibility in adult female mice offspring following a J-shaped pattern and through distinct mechanisms
    Raquel Santana da Cruz, Fabia de Oliveira Andrade, Vivian Montes de Oca Carioni, Mariana Papaléo Rosim, Mayara Lilian Paulino Miranda, Camile Castilho Fontelles, Pedro Vitoriano de Oliveira, Luis Fernando Barbisan, Inar Alves Castro, Thomas Prates Ong
    Food and Chemical Toxicology 2019 134
  • Lmo4 and Other LIM domain only factors are necessary and sufficient for multiple retinal cell type development
    Kangxin Jin, Dongchang Xiao, Bogi Andersen, Mengqing Xiang
    Developmental Neurobiology 2016 76 8
  • Recruitment and activation of SLK at the leading edge of migrating cells requires Src family kinase activity and the LIM-only protein 4
    Kyla D. Baron, Khalid Al-Zahrani, Jillian Conway, Cédrik Labrèche, Christopher J. Storbeck, Jane E. Visvader, Luc A. Sabourin
    Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 2015 1853 7
  • Impaired lactation in mice expressing dominant-negative FADD in mammary epithelium
    Mark Shackleton, Lorraine A. O'Reilly, Kate D. Sutherland, Mary L. Bath, Sarah Ellis, Andreas Strasser, Jane E. Visvader, Geoffrey J. Lindeman
    Developmental Dynamics 2009 238 4
  • LMO1 functions as an oncogene by regulating TTK expression and correlates with neuroendocrine differentiation of lung cancer
    Liqin Du, Zhenze Zhao, Milind Suraokar, Spencer S. Shelton, Xiuye Ma, Tzu-Hung Hsiao, John D. Minna, Ignacio Wistuba, Alexander Pertsemlidis
    Oncotarget 2018 9 51
  • LMO3 promotes gastric cancer cell invasion and proliferation through Akt-mTOR and Akt-GSK3β signaling
    Yan-Song Qiu, Ning-Ning Jiang, Yan Zhou, Kuai-Yun Yu, Hong-Yan Gong, Guang-Jun Liao
    International Journal of Molecular Medicine 2018
  • Gene expression profiling of triple-negative breast tumors with different expression of secreted protein acidic and cysteine rich (SPARC)
    Paulo R de Alcantara Filho, Flavia R Mangone, Ana C Pavanelli, Simone A de Bessa Garcia, Suely Nonogaki, Cynthia AB de Toledo Osório, Victor P de Andrade, Maria A Nagai
    Breast Cancer Management 2018 7 2
  • The determination of changes in the expression of genes for selected specific transcriptional factors in in vitro ductal breast cancer cells under the influence of paclitaxel
    Marta Ziaja-Sołtys, Jolanta Rzymowska
    Cellular and Molecular Biology Letters 2011 16 4
  • Basic science (May–June 2005)
    R. Sutherland, J. Scorer
    Breast Cancer Online 2005 8 10
  • Beadex , a Drosophila LIM domain only protein, function in follicle cells is essential for egg development and fertility
    Subhash Kairamkonda, Upendra Nongthomba
    Experimental Cell Research 2018 367 1
  • Oncogenic <i>Lmo3</i> cooperates with <i>Hen2</i> to induce hydrocephalus in mice
    Eriko Isogai, Kazuhiro Okumura, Megumi Saito, Yasuhiro Yoshizawa, Kyoko Itoh, So Tando, Miki Ohira, Seiki Haraguchi, Akira Nakagawara, Shinji Fushiki, Hiroki Nagase, Yuichi Wakabayashi
    Experimental Animals 2015 64 4
  • The LIM domain binding protein 1, Ldb1, has distinct roles in Neu-induced mammary tumorigenesis
    Sarra Ahmed, Benjamin R. Pryce, Khalid N. Al-Zahrani, Luc A. Sabourin
    Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 2018 1865 11

Article usage

Article usage: May 2005 to January 2021

AbstractFullPdf
May 200541592389
Jun 200538175130
Jul 2005168649
Aug 2005159854
Sep 2005109959
Oct 20051616089
Nov 2005139050
Dec 200595054
Total 2005532850874
Jan 200648641
Feb 2006157640
Mar 2006157036
Apr 200664419
May 2006114626
Jun 2006104626
Jul 200652520
Aug 200683417
Sep 2006123027
Oct 200662319
Nov 2006162820
Dec 2006132317
Total 2006121531308
Jan 200762317
Feb 200752114
Mar 2007102317
Apr 200711229
May 2007103326
Jun 200761715
Jul 2007131112
Aug 2007132338
Sep 20077126
Oct 200781710
Nov 200781212
Dec 200771714
Total 2007104231190
Jan 200881212
Feb 2008111511
Mar 200882431
Apr 2008121410
May 200811178
Jun 2008131813
Jul 200841614
Aug 20083996
Sep 2008561713
Oct 200829147
Nov 2008431010
Dec 20082866
Total 2008299162141
Jan 2009268313
Feb 200938176
Mar 200926187
Apr 200911186
May 200912248
Jun 200921199
Jul 2009293616
Aug 2009232513
Sep 2009233215
Oct 2009322012
Nov 200917812
Dec 2009371011
Total 2009295235428
Jan 20101254
Feb 201010911
Mar 20102497
Apr 20103557
May 201013157
Jun 201025176
Jul 201032125
Aug 201027125
Sep 201024226
Oct 2010221612
Nov 2010371412
Dec 201019125
Total 201028014887
Jan 2011211412
Feb 201115119
Mar 2011111313
Apr 20111268
May 2011101310
Jun 201118915
Jul 201133812
Aug 201119129
Sep 201118139
Oct 201119107
Nov 2011272619
Dec 201119116
Total 2011222146129
Jan 2012241212
Feb 2012171511
Mar 201233178
Apr 20122496
May 201245136
Jun 2012331714
Jul 201225128
Aug 20122451
Sep 20121175
Oct 20121186
Nov 2012931
Dec 201227122
Total 201228313080
Jan 20132845
Feb 20133697
Mar 20132164
Apr 20132744
May 2013843
Jun 20131823
Jul 2013261010
Aug 20131456
Sep 20131546
Oct 20132554
Nov 20131433
Dec 20131968
Total 20132516263
Jan 20141011
Feb 20142845
Mar 20141334
Apr 20143198
May 201447118
Jun 20141674
Jul 201425114
Aug 201417143
Sep 20141882
Oct 20142384
Nov 20142242
Dec 20142040
Total 20142708445
Jan 20151425
Feb 20152445
Mar 201542123
Apr 20151456
May 20151655
Jun 20151134
Jul 2015311
Aug 20151241
Sep 20153261
Oct 20151782
Nov 201515106
Dec 201520108
Total 20152207047
Jan 201623107
Feb 201614134
Mar 201627124
Apr 201615118
May 20161199
Jun 20162298
Jul 201620112
Aug 20161441
Sep 20161445
Oct 20162043
Nov 20161443
Dec 20161635
Total 20162109459
Jan 20171041
Feb 2017530
Mar 2017927
Apr 20172116
May 20171466
Jun 2017602
Jul 20171244
Aug 2017752
Sep 20171226
Oct 20171254
Nov 20171212
Dec 20171083
Total 20171304143
Jan 2018975
Feb 201820193
Mar 20188710
Apr 20188124
May 201817179
Jun 201811134
Jul 2018151215
Aug 2018928841
Sep 201829300
Oct 20181178
Nov 20184336
Dec 20180252
Total 2018214280107
Jan 2019071
Feb 2019182
Mar 20191104
Apr 20192307
May 20191115
Jun 20190125
Jul 2019198
Aug 20190109
Sep 2019184
Oct 20194216
Nov 20193147
Dec 20191234
Total 20191516362
Jan 20202183
Feb 2020053
Mar 202021611
Apr 2020193
May 20200130
Jun 2020145
Jul 2020161
Aug 20201143
Sep 2020084
Oct 20200157
Nov 20205135
Dec 20206150
Total 20201913645
Jan 20210101
Total 20210101
Total346533732709
PreviousNext
Back to top
Article Alerts
Email Article

Thank you for your interest in spreading the word on PNAS.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Overexpression of LMO4 induces mammary hyperplasia, promotes cell invasion, and is a predictor of poor outcome in breast cancer
(Your Name) has sent you a message from PNAS
(Your Name) thought you would like to see the PNAS web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
Overexpression of LMO4 induces mammary hyperplasia, promotes cell invasion, and is a predictor of poor outcome in breast cancer
Eleanor Y. M. Sum, Davendra Segara, Belinda Duscio, Mary L. Bath, Andrew S. Field, Robert L. Sutherland, Geoffrey J. Lindeman, Jane E. Visvader
Proceedings of the National Academy of Sciences May 2005, 102 (21) 7659-7664; DOI: 10.1073/pnas.0502990102

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Request Permissions
Share
Overexpression of LMO4 induces mammary hyperplasia, promotes cell invasion, and is a predictor of poor outcome in breast cancer
Eleanor Y. M. Sum, Davendra Segara, Belinda Duscio, Mary L. Bath, Andrew S. Field, Robert L. Sutherland, Geoffrey J. Lindeman, Jane E. Visvader
Proceedings of the National Academy of Sciences May 2005, 102 (21) 7659-7664; DOI: 10.1073/pnas.0502990102
Digg logo Reddit logo Twitter logo Facebook logo Google logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Mendeley logo Mendeley
Proceedings of the National Academy of Sciences of the United States of America: 102 (21)
Table of Contents

Submit

Sign up for Article Alerts

Jump to section

  • Article
    • Abstract
    • Materials and Methods
    • Results
    • Discussion
    • Acknowledgments
    • Footnotes
    • References
  • Figures & SI
  • Info & Metrics
  • PDF

You May Also be Interested in

Abstract depiction of a guitar and musical note
Science & Culture: At the nexus of music and medicine, some see disease treatments
Although the evidence is still limited, a growing body of research suggests music may have beneficial effects for diseases such as Parkinson’s.
Image credit: Shutterstock/agsandrew.
Large piece of gold
News Feature: Tracing gold's cosmic origins
Astronomers thought they’d finally figured out where gold and other heavy elements in the universe came from. In light of recent results, they’re not so sure.
Image credit: Science Source/Tom McHugh.
Dancers in red dresses
Journal Club: Friends appear to share patterns of brain activity
Researchers are still trying to understand what causes this strong correlation between neural and social networks.
Image credit: Shutterstock/Yeongsik Im.
White and blue bird
Hazards of ozone pollution to birds
Amanda Rodewald, Ivan Rudik, and Catherine Kling talk about the hazards of ozone pollution to birds.
Listen
Past PodcastsSubscribe
Goats standing in a pin
Transplantation of sperm-producing stem cells
CRISPR-Cas9 gene editing can improve the effectiveness of spermatogonial stem cell transplantation in mice and livestock, a study finds.
Image credit: Jon M. Oatley.

Similar Articles

Site Logo
Powered by HighWire
  • Submit Manuscript
  • Twitter
  • Facebook
  • RSS Feeds
  • Email Alerts

Articles

  • Current Issue
  • Special Feature Articles – Most Recent
  • List of Issues

PNAS Portals

  • Anthropology
  • Chemistry
  • Classics
  • Front Matter
  • Physics
  • Sustainability Science
  • Teaching Resources

Information

  • Authors
  • Editorial Board
  • Reviewers
  • Librarians
  • Press
  • Site Map
  • PNAS Updates

Feedback    Privacy/Legal

Copyright © 2021 National Academy of Sciences. Online ISSN 1091-6490