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Research Article

Bayesian coclustering of Anopheles gene expression time series: Study of immune defense response to multiple experimental challenges

Nicholas A. Heard, Christopher C. Holmes, David A. Stephens, David J. Hand, and George Dimopoulos
PNAS November 22, 2005 102 (47) 16939-16944; https://doi.org/10.1073/pnas.0408393102
Nicholas A. Heard
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Christopher C. Holmes
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David A. Stephens
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David J. Hand
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George Dimopoulos
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  1. Edited by James O. Berger, Duke University, Durham, NC (received for review November 11, 2004)

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Article Information

vol. 102 no. 47 16939-16944
DOI: 
https://doi.org/10.1073/pnas.0408393102
PubMed: 
16287981

Published By: 
National Academy of Sciences
Print ISSN: 
0027-8424
Online ISSN: 
1091-6490
History: 
  • Published in issue November 22, 2005.
  • Published first November 15, 2005.

Copyright & Usage: 
Copyright © 2005, The National Academy of Sciences

Author Information

  1. Nicholas A. Heard * , †,
  2. Christopher C. Holmes ‡ , §,
  3. David A. Stephens *,
  4. David J. Hand *, and
  5. George Dimopoulos † , ¶
  1. *Department of Mathematics, Imperial College London, Huxley Building, 180 Queens Gate, London SW7 2AZ, United Kingdom; ‡Oxford Centre for Gene Function, Department of Statistics, University of Oxford, Oxford OX1 3QX, United Kingdom; §MRC Mammalian Genetics Unit, Medical Research Council, Harwell, Oxford OX11 0RD, United Kingdom; and ¶Department of Molecular Microbiology and Immunology, Johns Hopkins School of Public Health, 615 North Wolfe Street, Baltimore, MD 21205
  1. Edited by James O. Berger, Duke University, Durham, NC (received for review November 11, 2004)

Footnotes

  • ↵ † To whom correspondence may be addressed. E-mail: n.heard{at}imperial.ac.uk or gdimopou{at}jhsph.edu.

  • Author contributions: N.A.H., C.C.H., and D.A.S. designed research and performed research; N.A.H. and G.D. analyzed data; and N.A.H., C.C.H., D.A.S., D.J.H., and G.D. wrote the paper.

  • Conflict of interest statement: No conflicts declared.

  • This paper was submitted directly (Track II) to the PNAS office.

  • Abbreviations: CV, cross-validation; EM, Expectation-Maximization; MC, Monte Carlo; L.m., Listeria monocytogenes; M.l., Micrococcus luteus; S.t., Salmonella typhimurium.

  • Copyright © 2005, The National Academy of Sciences

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Article usage

Article usage: November 2005 to January 2021

AbstractFullPdf
Nov 2005659127370
Dec 20054377771
Total 20051096204441
Jan 20064235863
Feb 20061834329
Mar 2006264946
Apr 2006233217
May 2006213120
Jun 2006123231
Jul 2006145127
Aug 2006142917
Sep 2006242831
Oct 2006253046
Nov 2006294924
Dec 2006181813
Total 2006812450364
Jan 2007121526
Feb 2007251725
Mar 2007341632
Apr 2007281336
May 2007212226
Jun 2007181923
Jul 2007191013
Aug 2007211328
Sep 200717810
Oct 2007162319
Nov 20076811
Dec 20078712
Total 2007225171261
Jan 2008261116
Feb 200871910
Mar 2008112912
Apr 2008101526
May 2008201213
Jun 2008242218
Jul 2008521913
Aug 2008381116
Sep 2008411447
Oct 2008491224
Nov 2008601525
Dec 2008581328
Total 2008396192248
Jan 2009331710
Feb 2009551115
Mar 2009361415
Apr 2009411419
May 2009371620
Jun 2009221311
Jul 2009431219
Aug 2009711410
Sep 2009281717
Oct 200931144
Nov 2009331716
Dec 2009211117
Total 2009451170173
Jan 20103153
Feb 201023178
Mar 201035811
Apr 201025713
May 201012144
Jun 20103197
Jul 201015164
Aug 201017129
Sep 201015188
Oct 201030249
Nov 201023129
Dec 20101974
Total 201027614989
Jan 201125146
Feb 201120105
Mar 201129710
Apr 2011122110
May 20111669
Jun 20111013
Jul 20111948
Aug 20112088
Sep 20111682
Oct 201115109
Nov 2011251614
Dec 20111483
Total 201122111387
Jan 20122366
Feb 20122296
Mar 20122197
Apr 2012171314
May 20122586
Jun 20129187
Jul 201230915
Aug 2012827
Sep 20121353
Oct 2012231214
Nov 2012151122
Dec 201211512
Total 2012217107119
Jan 2013212031
Feb 20132169
Mar 201317415
Apr 201323217
May 2013201814
Jun 201326922
Jul 201316614
Aug 20131136
Sep 20131974
Oct 201312184
Nov 201322157
Dec 20131289
Total 2013220116152
Jan 20141227
Feb 20142263
Mar 20142343
Apr 201427116
May 20141543
Jun 20141276
Jul 20141052
Aug 201422116
Sep 201418105
Oct 201418133
Nov 20148814
Dec 20142285
Total 20142098963
Jan 2015251017
Feb 201515512
Mar 20152058
Apr 2015171711
May 20151467
Jun 201511126
Jul 2015372
Aug 2015111011
Sep 20151564
Oct 201518514
Nov 20151449
Dec 201514513
Total 201517792114
Jan 201611312
Feb 201624620
Mar 201616324
Apr 20169417
May 20161179
Jun 20161696
Jul 20161632
Aug 20161132
Sep 20162185
Oct 20162982
Nov 20163149
Dec 20161986
Total 201621466114
Jan 20171679
Feb 20171672
Mar 20172138
Apr 2017942
May 20171675
Jun 2017545
Jul 201715103
Aug 20171556
Sep 20172033
Oct 20171997
Nov 20171013
Dec 20173323
Total 20171956256
Jan 20181083
Feb 201816187
Mar 201821228
Apr 201820191
May 201814142
Jun 201821190
Jul 201816166
Aug 201827202
Sep 201828163
Oct 20188176
Nov 20184232
Dec 20183202
Total 201818821242
Jan 20192190
Feb 20192123
Mar 201911810
Apr 20192288
May 20191157
Jun 2019184
Jul 2019468
Aug 20192910
Sep 20194124
Oct 20193157
Nov 20191384
Dec 20191383
Total 20192421868
Jan 202091011
Feb 2020175
Mar 2020594
Apr 2020996
May 20202114
Jun 2020294
Jul 2020352
Aug 2020522
Sep 202091410
Oct 2020685
Nov 2020963
Dec 202081012
Total 20206810068
Jan 20213177
Total 20213177
Total499225282466
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Bayesian coclustering of Anopheles gene expression time series: Study of immune defense response to multiple experimental challenges
Nicholas A. Heard, Christopher C. Holmes, David A. Stephens, David J. Hand, George Dimopoulos
Proceedings of the National Academy of Sciences Nov 2005, 102 (47) 16939-16944; DOI: 10.1073/pnas.0408393102

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Bayesian coclustering of Anopheles gene expression time series: Study of immune defense response to multiple experimental challenges
Nicholas A. Heard, Christopher C. Holmes, David A. Stephens, David J. Hand, George Dimopoulos
Proceedings of the National Academy of Sciences Nov 2005, 102 (47) 16939-16944; DOI: 10.1073/pnas.0408393102
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