New Research In
Physical Sciences
Social Sciences
Featured Portals
Articles by Topic
Biological Sciences
Featured Portals
Articles by Topic
- Agricultural Sciences
- Anthropology
- Applied Biological Sciences
- Biochemistry
- Biophysics and Computational Biology
- Cell Biology
- Developmental Biology
- Ecology
- Environmental Sciences
- Evolution
- Genetics
- Immunology and Inflammation
- Medical Sciences
- Microbiology
- Neuroscience
- Pharmacology
- Physiology
- Plant Biology
- Population Biology
- Psychological and Cognitive Sciences
- Sustainability Science
- Systems Biology
Table of Contents
March 01, 2005; vol. 102 no. 9
In This Issue
Biography
- You have accessBiography of Cornelia I. Bargmann
- Inaugural Article
Melissa MarinoSee companion article:
- A circuit for navigation in Caenorhabditis elegans- Feb 02, 2005
Physical Sciences
Applied Mathematics
- You have accessInferring network mechanisms: The Drosophila melanogaster protein interaction network
- From the Cover
Manuel Middendorf, Etay Ziv, and Chris H. WigginsSee companion article:
Applied Physical Sciences
- You have accessHard superconducting nitridesXiao-Jia Chen, Viktor V. Struzhkin, Zhigang Wu, Maddury Somayazulu, Jiang Qian, Simon Kung, Axel Nørlund Christensen, Yusheng Zhao, Ronald E. Cohen, Ho-kwang Mao, and Russell J. Hemley
Chemistry
- You have accessLabel-free detection of small-molecule–protein interactions by using nanowire nanosensorsWayne U. Wang, Chuo Chen, Keng-hui Lin, Ying Fang, and Charles M. Lieber
Engineering
- You have accessGrowth and shape stability of a biological membrane adhesion complex in the diffusion-mediated regimeV. B. Shenoy and L. B. Freund
Biological Sciences
Applied Biological Sciences
- You have accessMullerian inhibiting substance suppresses tumor growth in the C3(1)T antigen transgenic mouse mammary carcinoma modelV. Gupta, J. L. Carey, H. Kawakubo, A. Muzikansky, J. E. Green, P. K. Donahoe, D. T. MacLaughlin, and S. Maheswaran
Biochemistry
- You have accessStructure of a mitochondrial supercomplex formed by respiratory-chain complexes I and IIINatalia V. Dudkina, Holger Eubel, Wilko Keegstra, Egbert J. Boekema, and Hans-Peter Braun
- You have accessThe initial substrate-binding site of γ-secretase is located on presenilin near the active siteAnna Y. Kornilova, Frédéric Bihel, Chittaranjan Das, and Michael S. Wolfe
See companion article:
- This Week in PNAS- Mar 01, 2005
- You have accessIdentification of a nitrogenase FeMo cofactor precursor on NifEN complexYilin Hu, Aaron W. Fay, and Markus W. Ribbe
- You have accessIntramembrane aspartic acid in SCAP protein governs cholesterol-induced conformational changeJamison D. Feramisco, Arun Radhakrishnan, Yukio Ikeda, Julian Reitz, Michael S. Brown, and Joseph L. Goldstein
- You have accessCrystal structure of DNA sequence specificity subunit of a type I restriction-modification enzyme and its functional implicationsJeong-Sun Kim, Andy DeGiovanni, Jaru Jancarik, Paul D. Adams, Hisao Yokota, Rosalind Kim, and Sung-Hou Kim
- You have accessAssembly of the bacteriophage T4 primosome: Single-molecule and ensemble studiesZhiquan Zhang, Michelle M. Spiering, Michael A. Trakselis, Faoud T. Ishmael, Jun Xi, Stephen J. Benkovic, and Gordon G. Hammes
- You have accessStudy of the high-potential iron sulfur protein in Halorhodospira halophila confirms that it is distinct from cytochrome c as electron carrierClément Lieutaud, Jean Alric, Marielle Bauzan, Wolfgang Nitschke, and Barbara Schoepp-Cothenet
- You have accessThe eukaryotic P loop NTPase Nbp35: An essential component of the cytosolic and nuclear iron–sulfur protein assembly machineryAnja Hausmann, Daili J. Aguilar Netz, Janneke Balk, Antonio J. Pierik, Ulrich Mühlenhoff, and Roland Lill
- You have accessSterol structure determines the separation of phases and the curvature of the liquid-ordered phase in model membranes
- From the Cover
Kirsten Bacia, Petra Schwille, and Teymuras Kurzchalia
Biophysics
- You have accessLabel-free detection of small-molecule–protein interactions by using nanowire nanosensorsWayne U. Wang, Chuo Chen, Keng-hui Lin, Ying Fang, and Charles M. Lieber
- You have accessGrowth and shape stability of a biological membrane adhesion complex in the diffusion-mediated regimeV. B. Shenoy and L. B. Freund
- You have accessFast, long-range, reversible conformational fluctuations in nucleosomes revealed by single-pair fluorescence resonance energy transferMiroslav Tomschik, Haocheng Zheng, Ken van Holde, Jordanka Zlatanova, and Sanford H. Leuba
- You have accessProbing site-specific conformational distributions in protein folding with solid-state NMRRobert H. Havlin and Robert Tycko
Cell Biology
- You have accessBarrier-to-autointegration factor is required to segregate and enclose chromosomes within the nuclear envelope and assemble the nuclear laminaAyelet Margalit, Miriam Segura-Totten, Yosef Gruenbaum, and Katherine L. Wilson
- You have accessHuman mesenchymal stem cells in rodent whole-embryo culture are reprogrammed to contribute to kidney tissuesTakashi Yokoo, Toya Ohashi, Jin Song Shen, Ken Sakurai, Yoichi Miyazaki, Yasunori Utsunomiya, Masanori Takahashi, Yoshio Terada, Yoshikatsu Eto, Tetsuya Kawamura, Noriko Osumi, and Tatsuo Hosoya
- You have accessRhodopsin C terminus, the site of mutations causing retinal disease, regulates trafficking by binding to ADP-ribosylation factor 4 (ARF4)Dusanka Deretic, Andrew H. Williams, Nancy Ransom, Valerie Morel, Paul A. Hargrave, and Anatol Arendt
- You have accessMolecular cloning of TRPC3a, an N-terminally extended, store-operated variant of the human C3 transient receptor potential channelEda Yildirim, Brian T. Kawasaki, and Lutz Birnbaumer
Developmental Biology
- You have accessEnforced Bcl-2 expression overrides serum and feeder cell requirements for mouse embryonic stem cell self-renewalToshiyuki Yamane, Scott J. Dylla, Manja Muijtjens, and Irving L. Weissman
- You have accessRegulation of osteoblastogenesis and bone mass by Wnt10bChristina N. Bennett, Kenneth A. Longo, Wendy S. Wright, Larry J. Suva, Timothy F. Lane, Kurt D. Hankenson, and Ormond A. MacDougald
Evolution
- You have accessJuvenile hormone, reproduction, and worker behavior in the neotropical social wasp Polistes canadensisTugrul Giray, Manuela Giovanetti, and Mary Jane West-Eberhard
Genetics
- You have accessAssociation of tissue-specific differentially methylated regions (TDMs) with differential gene expressionFei Song, Joseph F. Smith, Makoto T. Kimura, Arlene D. Morrow, Tomoki Matsuyama, Hiroki Nagase, and William A. Held
- You have accessMutations in Serac1 or Synj2 cause proximal t haplotype-mediated male mouse sterility but not transmission ratio distortionJohn C. Schimenti, Jennifer L. Reynolds, and Antonio Planchart
- You have accessAbrupt disruption of capping and a single source for recombinationally elongated telomeres in Kluyveromyces lactisZeki Topcu, Kristy Nickles, Charity Davis, and Michael J. McEachern
- You have accessComparative sequencing provides insights about the structure and conservation of marsupial and monotreme genomesElliott H. Margulies, NISC Comparative Sequencing Program* † ‡ , Valerie V. B. Maduro, Pamela J. Thomas, Jeffery P. Tomkins, Chris T. Amemiya, Meizhong Luo, and Eric D. Green
Immunology
- You have accessCrystal structure of HLA-G: A nonclassical MHC class I molecule expressed at the fetal–maternal interfaceCraig S. Clements, Lars Kjer-Nielsen, Lyudmila Kostenko, Hilary L. Hoare, Michelle A. Dunstone, Eric Moses, Katy Freed, Andrew G. Brooks, Jamie Rossjohn, and James McCluskey
See companion article:
- This Week in PNAS- Mar 01, 2005
- You have accessAn atomic resolution view of ICAM recognition in a complex between the binding domains of ICAM-3 and integrin αLβ2Gang Song, Yuting Yang, Jin-huan Liu, Jose M. Casasnovas, Motomu Shimaoka, Timothy A. Springer, and Jia-huai Wang
- You have accessCross-regulation of TNF and IFN-α in autoimmune diseasesA. Karolina Palucka, Jean-Philippe Blanck, Lynda Bennett, Virginia Pascual, and Jacques Banchereau
- You have accessImmunogenicity in humans of an edible vaccine for hepatitis BYasmin Thanavala, Martin Mahoney, Sribani Pal, Adrienne Scott, Liz Richter, Nachimuthu Natarajan, Patti Goodwin, Charles J. Arntzen, and Hugh S. Mason
- You have accessModulation of CD1d-restricted NKT cell responses by using N-acyl variants of α-galactosylceramidesKarl O. A. Yu, Jin S. Im, Alberto Molano, Yves Dutronc, Petr A. Illarionov, Claire Forestier, Nagatoshi Fujiwara, Isa Arias, Sachiko Miyake, Takashi Yamamura, Young-Tae Chang, Gurdyal S. Besra, and Steven A. Porcelli
Medical Sciences
- You have accessPlatelet-derived growth factor C induces liver fibrosis, steatosis, and hepatocellular carcinomaJean S. Campbell, Steven D. Hughes, Debra G. Gilbertson, Thomas E. Palmer, Matthew S. Holdren, Aaron C. Haran, Melissa M. Odell, Renay L. Bauer, Hong-Ping Ren, Harald S. Haugen, Matthew M. Yeh, and Nelson Fausto
- You have accessComparative analysis of two clinically active BCR-ABL kinase inhibitors reveals the role of conformation-specific binding in resistanceMichael R. Burgess, Brian J. Skaggs, Neil P. Shah, Francis Y. Lee, and Charles L. Sawyers
- You have accessIdentification of mouse SLC39A8 as the transporter responsible for cadmium-induced toxicity in the testisTimothy P. Dalton, Lei He, Bin Wang, Marian L. Miller, Li Jin, Keith F. Stringer, Xiaoqing Chang, C. Stuart Baxter, and Daniel W. Nebert
- You have accessCircadian sensitivity to the chemotherapeutic agent cyclophosphamide depends on the functional status of the CLOCK/BMAL1 transactivation complex
- From the Cover
Victoria Y. Gorbacheva, Roman V. Kondratov, Renliang Zhang, Srujana Cherukuri, Andrei V. Gudkov, Joseph S. Takahashi, and Marina P. AntochSee companion article:
- You have accessParkinson-like syndrome induced by continuous MPTP infusion: Convergent roles of the ubiquitin-proteasome system and α-synucleinFrancesco Fornai, Oliver M. Schlüter, Paola Lenzi, Marco Gesi, Riccardo Ruffoli, Michela Ferrucci, Gloria Lazzeri, Carla L. Busceti, Fabrizio Pontarelli, Giuseppe Battaglia, Antonio Pellegrini, Ferdinando Nicoletti, Stefano Ruggieri, Antonio Paparelli, and Thomas C. Südhof
- You have accessMicrocomputed tomography colonography for polyp detection in an in vivo mouse tumor modelPerry J. Pickhardt, Richard B. Halberg, Andrew J. Taylor, Ben Y. Durkee, Jason Fine, Fred T. Lee Jr., and Jamey P. Weichert
- You have accessCirculating transcriptome reveals markers of atherosclerosisWillmar D. Patino, Omar Y. Mian, Ju-Gyeong Kang, Satoaki Matoba, Linda D. Bartlett, Brenda Holbrook, Hugh H. Trout III, Louis Kozloff, and Paul M. Hwang
- You have accessSynergistic proinflammatory responses induced by polymicrobial colonization of epithelial surfacesAdam J. Ratner, Elena S. Lysenko, Marina N. Paul, and Jeffrey N. Weiser
- You have accessAntagonist of growth hormone-releasing hormone induces apoptosis in LNCaP human prostate cancer cells through a Ca2+-dependent pathwayZoltan Rekasi, Tamas Czompoly, Andrew V. Schally, Ferenc Boldizsar, Jozsef L. Varga, Marta Zarandi, Timea Berki, Reka A. Horvath, and Peter Nemeth
Microbiology
- You have accessGenome trimming: A unique strategy for replication control employed by Borna disease virusUrs Schneider, Martin Schwemmle, and Peter Staeheli
- You have accessChlamydia pneumoniae infection promotes a proliferative phenotype in the vasculature through Egr-1 activation in vitro and in vivoJan Rupp, Thomas Hellwig-Burgel, Viola Wobbe, Ulrike Seitzer, Ernst Brandt, and Matthias Maass
- You have accessLessons from Escherichia coli genes similarly regulated in response to nitrogen and sulfur limitationPrasad Gyaneshwar, Oleg Paliy, Jon McAuliffe, Adriane Jones, Michael I. Jordan, and Sydney Kustu
- You have accessProline suppresses apoptosis in the fungal pathogen Colletotrichum trifolii
- From the Cover
Changbin Chen and Martin B. DickmanSee companion article:
- This Week in PNAS- Mar 01, 2005
- You have accessGenomic characterization of non-O1, non-O139 Vibrio cholerae reveals genes for a type III secretion systemMichelle Dziejman, Davide Serruto, Vincent C. Tam, Derek Sturtevant, Pornphan Diraphat, Shah M. Faruque, M. Hasibur Rahman, John F. Heidelberg, Jeremy Decker, Li Li, Kate T. Montgomery, George Grills, Raju Kucherlapati, and John J. Mekalanos
- You have accessDemonstration of toxicity to fish and to mammalian cells by Pfiesteria species: Comparison of assay methods and strainsJoAnn M. Burkholder, Andrew S. Gordon, Peter D. Moeller, J. Mac Law, Kathryn J. Coyne, Alan J. Lewitus, John S. Ramsdell, Harold G. Marshall, Nora J. Deamer, S. Craig Cary, Jason W. Kempton, Steven L. Morton, and Parke A. Rublee
Neuroscience
- You have accessA circuit for navigation in Caenorhabditis elegans
- Inaugural Article
Jesse M. Gray, Joseph J. Hill, and Cornelia I. BargmannSee companion article:
- Biography of Cornelia I. Bargmann- Feb 22, 2005
- You have accessDissection of synaptic excitability phenotypes by using a dominant-negative Shaker K+ channel subunitTimothy J. Mosca, Robert A. Carrillo, Benjamin H. White, and Haig Keshishian
- You have accessUric acid protects against secondary damage after spinal cord injuryGwen S. Scott, Salvatore Cuzzocrea, Tiziana Genovese, Hilary Koprowski, and D. Craig Hooper
- You have accessPhosphorylation of spinophilin by ERK and cyclin-dependent PK 5 (Cdk5)Marie Futter, Ken Uematsu, Stewart A. Bullock, Yong Kim, Hugh C. Hemmings Jr., Akinori Nishi, Paul Greengard, and Angus C. Nairn
- You have accessAmphetamine induces dopamine efflux through a dopamine transporter channelKristopher M. Kahlig, Francesca Binda, Habibeh Khoshbouei, Randy D. Blakely, Douglas G. McMahon, Jonathan A. Javitch, and Aurelio Galli
- You have accessDiagnosis of human prion diseaseJiri G. Safar, Michael D. Geschwind, Camille Deering, Svetlana Didorenko, Mamta Sattavat, Henry Sanchez, Ana Serban, Martin Vey, Henry Baron, Kurt Giles, Bruce L. Miller, Stephen J. DeArmond, and Stanley B. Prusiner
- You have accessSingle-neuron responses and neuronal decisions in a vernier taskYing Zhang and R. Clay Reid
See companion article:
- This Week in PNAS- Mar 01, 2005
- You have accessDopamine supersensitivity correlates with D2High states, implying many paths to psychosisPhilip Seeman, David Weinshenker, Remi Quirion, Lalit K. Srivastava, Sanjeev K. Bhardwaj, David K. Grandy, Richard T. Premont, Tatyana D. Sotnikova, Patricia Boksa, Mufida El-Ghundi, Brian F. O'Dowd, Susan R. George, Melissa L. Perreault, Pekka T. Männistö, Siobhan Robinson, Richard D. Palmiter, and Teresa Tallerico
Psychology
- You have accessAgrammatic but numerate
- From the Cover
Rosemary A. Varley, Nicolai J. C. Klessinger, Charles A. J. Romanowski, and Michael SiegalSee companion article:
- The independence of language and mathematical reasoning- Feb 22, 2005
Commentaries
See companion article:
See companion article:
See companion article:
See companion article: