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Research Article

Mouse telocentric sequences reveal a high rate of homogenization and possible role in Robertsonian translocation

Paul Kalitsis, Belinda Griffiths, and K. H. Andy Choo
  1. *Murdoch Childrens Research Institute, Royal Children's Hospital, Melbourne, Victoria 3052, Australia; and
  2. †Department of Pediatrics, University of Melbourne, Royal Children's Hospital, Melbourne, Victoria 3052, Australia

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PNAS June 6, 2006 103 (23) 8786-8791; https://doi.org/10.1073/pnas.0600250103
Paul Kalitsis
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  • For correspondence: paul.kalitsis@mcri.edu.au andy.choo@mcri.edu.au
Belinda Griffiths
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K. H. Andy Choo
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  • For correspondence: paul.kalitsis@mcri.edu.au andy.choo@mcri.edu.au
  1. Edited by Elizabeth Blackburn, University of California, San Francisco, CA, and approved April 17, 2006 (received for review January 10, 2006)

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Article Information

vol. 103 no. 23 8786-8791
DOI: 
https://doi.org/10.1073/pnas.0600250103
PubMed: 
16731628

Published By: 
National Academy of Sciences
Print ISSN: 
0027-8424
Online ISSN: 
1091-6490
History: 
  • Published in issue June 6, 2006.
  • Published first May 26, 2006.

Copyright & Usage: 
© 2006 by The National Academy of Sciences of the USA

Author Information

  1. Paul Kalitsis * , † , ‡ ,
  2. Belinda Griffiths * , † , and
  3. K. H. Andy Choo * , † , ‡
  1. *Murdoch Childrens Research Institute, Royal Children's Hospital, Melbourne, Victoria 3052, Australia; and
  2. †Department of Pediatrics, University of Melbourne, Royal Children's Hospital, Melbourne, Victoria 3052, Australia
  1. Edited by Elizabeth Blackburn, University of California, San Francisco, CA, and approved April 17, 2006 (received for review January 10, 2006)

Footnotes

  • ‡To whom correspondence may be addressed. E-mail: paul.kalitsis{at}mcri.edu.au or andy.choo{at}mcri.edu.au
  • Author contributions: P.K. designed research; P.K. and B.G. performed research; P.K., B.G., and K.H.A.C. analyzed data; and P.K. and K.H.A.C. wrote the paper.

  • Conflict of interest statement: No conflicts declared.

  • This paper was submitted directly (Track II) to the PNAS office.

  • Data deposition: The sequences reported in this paper have been deposited in the GenBank database (accession nos. DQ322707–DQ322722).

  • Abbreviations:

    Abbreviations:

    MEF,
    mouse embryonic fibroblast;
    PFGE,
    pulsed-field gel electrophoresis;
    tL1,
    truncated long interspersed nucleotide element 1;
    CENP,
    centromere protein;
    Rob,
    Robertsonian;
    p-tel,
    p-telomeric.
  • © 2006 by The National Academy of Sciences of the USA

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Article usage

Article usage: May 2006 to April 2021

AbstractFullPdf
May 200642038
Jun 200617077103
Jul 2006194340
Aug 2006122228
Sep 2006312724
Oct 2006181914
Nov 2006252620
Dec 2006262313
Total 2006343237280
Jan 2007143837
Feb 2007121920
Mar 2007113324
Apr 200772921
May 200742213
Jun 200772426
Jul 200731312
Aug 20076146
Sep 200781010
Oct 200792714
Nov 200713188
Dec 20075176
Total 200799264197
Jan 20088279
Feb 20085126
Mar 200810108
Apr 20081397
May 200814309
Jun 200822197
Jul 200831149
Aug 200820106
Sep 20082948
Oct 20081574
Nov 20082786
Dec 200819106
Total 200821316085
Jan 20092748
Feb 20093976
Mar 20091250
Apr 20091233
May 20092275
Jun 200922199
Jul 200910126
Aug 20091284
Sep 2009624
Oct 200916617
Nov 200911720
Dec 200918413
Total 20092078495
Jan 201010313
Feb 2010141550
Mar 201021914
Apr 20101458
May 20105196
Jun 20105105
Jul 20107125
Aug 20109135
Sep 201010145
Oct 20108206
Nov 201021912
Dec 20101092
Total 2010134138131
Jan 201110100
Feb 201110183
Mar 201111204
Apr 2011131914
May 2011111810
Jun 20117177
Jul 2011121210
Aug 201112144
Sep 201118176
Oct 20112899
Nov 2011221910
Dec 201125188
Total 201117919185
Jan 201217174
Feb 201222329
Mar 201216219
Apr 201217326
May 2012151810
Jun 20129104
Jul 201212265
Aug 20129103
Sep 201215138
Oct 20124148
Nov 201242615
Dec 20127123
Total 201214723184
Jan 20131682
Feb 201315149
Mar 2013272414
Apr 20131468
May 201318238
Jun 201314135
Jul 20132484
Aug 201381611
Sep 201335348
Oct 201313166
Nov 201314102
Dec 201342243
Total 201324019680
Jan 201415168
Feb 201416195
Mar 201448627
Apr 201435349
May 201412152
Jun 20141298
Jul 201413161
Aug 201415215
Sep 201411222
Oct 201425102
Nov 20141668
Dec 20141681
Total 201423423858
Jan 201516192
Feb 20151895
Mar 201512207
Apr 201518178
May 20151384
Jun 2015884
Jul 2015395
Aug 201510145
Sep 20155103
Oct 201516309
Nov 201516339
Dec 201526228
Total 201516119969
Jan 2016453616
Feb 201613184
Mar 201684210
Apr 201611199
May 2016133610
Jun 20167210
Jul 201628167
Aug 201620144
Sep 20162094
Oct 201617185
Nov 201619197
Dec 20161493
Total 201621525779
Jan 20178133
Feb 2017102911
Mar 201711156
Apr 20171343
May 201711206
Jun 201717182
Jul 201713134
Aug 201716148
Sep 201712189
Oct 201710222
Nov 20171292
Dec 201751211
Total 201713818767
Jan 2018141510
Feb 2018414027
Mar 201823337
Apr 201820251
May 201833316
Jun 201829347
Jul 201823292
Aug 201825264
Sep 201854522
Oct 20188655
Nov 201805511
Dec 201803013
Total 201827043595
Jan 20190252
Feb 20191413
Mar 20191318
Apr 20192477
May 201923015
Jun 20190265
Jul 20192177
Aug 20192159
Sep 20191208
Oct 201934611
Nov 20193388
Dec 20190525
Total 20191738888
Jan 20203457
Feb 20201194
Mar 20200227
Apr 20201237
May 202004412
Jun 202013910
Jul 20202223
Aug 202011910
Sep 20201243
Oct 202085018
Nov 20206377
Dec 202043117
Total 202028375105
Jan 20212478
Feb 20211287
Mar 202124515
Apr 2021656
Total 20211112536
Total263637051634
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Mouse telocentric sequences reveal a high rate of homogenization and possible role in Robertsonian translocation
Paul Kalitsis, Belinda Griffiths, K. H. Andy Choo
Proceedings of the National Academy of Sciences Jun 2006, 103 (23) 8786-8791; DOI: 10.1073/pnas.0600250103

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Mouse telocentric sequences reveal a high rate of homogenization and possible role in Robertsonian translocation
Paul Kalitsis, Belinda Griffiths, K. H. Andy Choo
Proceedings of the National Academy of Sciences Jun 2006, 103 (23) 8786-8791; DOI: 10.1073/pnas.0600250103
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