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Table of Contents
July 25, 2006; vol. 103 no. 30
This Week in PNAS
Physical Sciences
Applied Physical Sciences
Geology
- You have accessA stable isotope aridity index for terrestrial environmentsNaomi E. Levin, Thure E. Cerling, Benjamin H. Passey, John M. Harris, and James R. Ehleringer
Mathematics
Social Sciences
Psychology
- You have accessThe influence of meaning on the perception of speech soundsNina Kazanina, Colin Phillips, and William Idsardi
Sustainability Science
- You have accessEnvironmental, economic, and energetic costs and benefits of biodiesel and ethanol biofuels
- From the Cover
Jason Hill, Erik Nelson, David Tilman, Stephen Polasky, and Douglas TiffanySee companion article:
- In This Issue- Jul 25, 2006
Biological Sciences
Biochemistry
- You have accessActive cytosine demethylation triggered by a nuclear receptor involves DNA strand breaksClémence Kress, Hélène Thomassin, and Thierry Grange
- You have accessTopoisomerase IIIα and Bloom’s helicase can resolve a mobile double Holliday junction substrate through convergent branch migrationJody L. Plank, Jianhong Wu, and Tao-shih Hsieh
- You have accessThe 2.7-Å crystal structure of a 194-kDa homodimeric fragment of the 6-deoxyerythronolide B synthaseYinyan Tang, Chu-Young Kim, Irimpan I. Mathews, David E. Cane, and Chaitan Khosla
Biophysics
- You have accessA two-dimensional view of the folding energy landscape of cytochrome cJames H. Werner, Raymond Joggerst, R. Brian Dyer, and Peter M. Goodwin
- You have accessSingle-molecule dynamics of phytochrome-bound fluorophores probed by fluorescence correlation spectroscopyAbigail E. Miller, Amanda J. Fischer, Ted Laurence, Christopher W. Hollars, Richard J. Saykally, J. Clark Lagarias, and Thomas Huser
Cell Biology
- You have accessA global topology map of the Saccharomyces cerevisiae membrane proteomeHyun Kim, Karin Melén, Marie Österberg, and Gunnar von Heijne
- You have accessPhenotypic effects of membrane protein overexpression in Saccharomyces cerevisiaeMarie Österberg, Hyun Kim, Jonas Warringer, Karin Melén, Anders Blomberg, and Gunnar von Heijne
- You have accessOvarian cancer side population defines cells with stem cell-like characteristics and Mullerian Inhibiting Substance responsivenessPaul P. Szotek, Rafael Pieretti-Vanmarcke, Peter T. Masiakos, Daniela M. Dinulescu, Denise Connolly, Rosemary Foster, David Dombkowski, Frederic Preffer, David T. MacLaughlin, and Patricia K. Donahoe
- You have accessMAGE-A tumor antigens target p53 transactivation function through histone deacetylase recruitment and confer resistance to chemotherapeutic agentsMartin Monte, Marta Simonatto, Leticia Y. Peche, Debora R. Bublik, Stefania Gobessi, Marco A. Pierotti, Monica Rodolfo, and Claudio Schneider
- You have accessBiophysical model of self-organized spindle formation patterns without centrosomes and kinetochoresStuart C. Schaffner and Jorge V. José
- You have accessAlzheimer's disease β-amyloid peptides are released in association with exosomesLawrence Rajendran, Masanori Honsho, Tobias R. Zahn, Patrick Keller, Kathrin D. Geiger, Paul Verkade, and Kai Simons
- Open AccessAn amphipathic helix targets serum and glucocorticoid-induced kinase 1 to the endoplasmic reticulum-associated ubiquitin-conjugation machineryMaria Francisca Arteaga, Lin Wang, Tommer Ravid, Mark Hochstrasser, and Cecilia M. Canessa
Developmental Biology
- You have accessInfluence of sex chromosome constitution on the genomic imprinting of germ cellsGabriela Durcova-Hills, Petra Hajkova, Stephen Sullivan, Sheila Barton, M. Azim Surani, and Anne McLaren
- You have accessA threshold of GATA4 and GATA6 expression is required for cardiovascular developmentMei Xin, Christopher A. Davis, Jeffery D. Molkentin, Ching-Ling Lien, Stephen A. Duncan, James A. Richardson, and Eric N. Olson
- You have accessMolecular evidence for deep evolutionary roots of bilaterality in animal development
- From the Cover
David Q. Matus, Kevin Pang, Heather Marlow, Casey W. Dunn, Gerald H. Thomsen, and Mark Q. MartindaleSee companion article:
- In This Issue- Jul 25, 2006
Ecology
- You have accessA stable isotope aridity index for terrestrial environmentsNaomi E. Levin, Thure E. Cerling, Benjamin H. Passey, John M. Harris, and James R. Ehleringer
- You have accessEnvironmental, economic, and energetic costs and benefits of biodiesel and ethanol biofuels
- From the Cover
Jason Hill, Erik Nelson, David Tilman, Stephen Polasky, and Douglas TiffanySee companion article:
- In This Issue- Jul 25, 2006
- Open AccessParasites dominate food web linksKevin D. Lafferty, Andrew P. Dobson, and Armand M. Kuris
Environmental Sciences
- Open AccessExtreme heat reduces and shifts United States premium wine production in the 21st centuryM. A. White, N. S. Diffenbaugh, G. V. Jones, J. S. Pal, and F. Giorgi
Evolution
- You have accessRapid Asia–Europe–North America geographic dispersal of earliest Eocene primate Teilhardina during the Paleocene–Eocene Thermal MaximumThierry Smith, Kenneth D. Rose, and Philip D. Gingerich
- Open AccessAdaptive evolution by mutations in the FLO11 geneManuel Fidalgo, Ramon R. Barrales, Jose I. Ibeas, and Juan Jimenez
Genetics
- You have accessMouse genomic representational oligonucleotide microarray analysis: Detection of copy number variations in normal and tumor specimensB. Lakshmi, Ira M. Hall, Christopher Egan, Joan Alexander, Anthony Leotta, John Healy, Lars Zender, Mona S. Spector, Wen Xue, Scott W. Lowe, Michael Wigler, and Robert Lucito
- Open AccessA Sanger/pyrosequencing hybrid approach for the generation of high-quality draft assemblies of marine microbial genomesSusanne M. D. Goldberg, Justin Johnson, Dana Busam, Tamara Feldblyum, Steve Ferriera, Robert Friedman, Aaron Halpern, Hoda Khouri, Saul A. Kravitz, Federico M. Lauro, Kelvin Li, Yu-Hui Rogers, Robert Strausberg, Granger Sutton, Luke Tallon, Torsten Thomas, Eli Venter, Marvin Frazier, and J. Craig Venter
- Open AccessHeritable and stable gene knockdown in ratsChristina Tenenhaus Dann, Alma L. Alvarado, Robert E. Hammer, and David L. Garbers
Immunology
- You have accessGlycolipid α-C-galactosylceramide is a distinct inducer of dendritic cell function during innate and adaptive immune responses of miceShin-ichiro Fujii, Kanako Shimizu, Hiroaki Hemmi, Mikiko Fukui, Anthony J. Bonito, Guangwu Chen, Richard W. Franck, Moriya Tsuji, and Ralph M. Steinman
- You have accessTransfer of NKG2D and MICB at the cytotoxic NK cell immune synapse correlates with a reduction in NK cell cytotoxic functionPedro Roda-Navarro, Mar Vales-Gomez, Susan E. Chisholm, and Hugh T. Reyburn
- Open AccessConsequences of receptor editing at the λ locus: Multireactivity and light chain secretionColleen M. Doyle, Jiong Han, Martin G. Weigert, and Eline T. Luning Prak
Medical Sciences
- You have accessTransgenic mice rich in endogenous omega-3 fatty acids are protected from colitisChristian A. Hudert, Karsten H. Weylandt, Yan Lu, Jingdong Wang, Song Hong, Axel Dignass, Charles N. Serhan, and Jing X. Kang
See companion article:
- In This Issue- Jul 25, 2006
- Open AccessDrusen, choroidal neovascularization, and retinal pigment epithelium dysfunction in SOD1-deficient mice: A model of age-related macular degenerationYutaka Imamura, Setsuko Noda, Kouhei Hashizume, Kei Shinoda, Mineko Yamaguchi, Satoshi Uchiyama, Takahiko Shimizu, Yutaka Mizushima, Takuji Shirasawa, and Kazuo Tsubota
- Open AccessA polymorphism within a conserved β1-adrenergic receptor motif alters cardiac function and β-blocker response in human heart failureStephen B. Liggett, Jeanne Mialet-Perez, Surai Thaneemit-Chen, Stewart A. Weber, Scott M. Greene, Danielle Hodne, Bradley Nelson, Jennifer Morrison, Michael J. Domanski, Lynne E. Wagoner, William T. Abraham, Jeffrey L. Anderson, John F. Carlquist, Heidi J. Krause-Steinrauf, Laura C. Lazzeroni, J. David Port, Philip W. Lavori, and Michael R. Bristow
- You have accessNoninvasive imaging of islet grafts using positron-emission tomographyYuxin Lu, Hoa Dang, Blake Middleton, Zesong Zhang, Lorraine Washburn, David B. Stout, Martha Campbell-Thompson, Mark A. Atkinson, Michael Phelps, Sanjiv Sam Gambhir, Jide Tian, and Daniel L. Kaufman
- You have accessAntioxidants reduce cone cell death in a model of retinitis pigmentosaKeiichi Komeima, Brian S. Rogers, Lili Lu, and Peter A. Campochiaro
- You have accessGenes and pathways downstream of telomerase in melanoma metastasisSepideh Bagheri, Mehdi Nosrati, Shang Li, Sylvia Fong, Sima Torabian, Javier Rangel, Dan H. Moore, Scot Federman, Rebecca R. LaPosa, Frederick L. Baehner, Richard W. Sagebiel, James E. Cleaver, Christopher Haqq, Robert J. Debs, Elizabeth H. Blackburn, and Mohammed Kashani-Sabet
- You have accessHuman prions and plasma lipoproteinsJiri G. Safar, Holger Wille, Michael D. Geschwind, Camille Deering, Diane Latawiec, Ana Serban, David J. King, Giuseppe Legname, Karl H. Weisgraber, Robert W. Mahley, Bruce L. Miller, Stephen J. DeArmond, and Stanley B. Prusiner
- You have accessHsp90 inhibition transiently activates Src kinase and promotes Src-dependent Akt and Erk activationFumitaka Koga, Wanping Xu, Tatiana S. Karpova, James G. McNally, Roland Baron, and Len Neckers
- You have accessBenefit of farnesoid X receptor inhibition in obstructive cholestasisCatherine Stedman, Christopher Liddle, Sally Coulter, Junichiro Sonoda, Jacqueline G. Alvarez, Ronald M. Evans, and Michael Downes
- You have accessUtilization of host SR protein kinases and RNA-splicing machinery during viral replicationTakeshi Fukuhara, Takamitsu Hosoya, Saki Shimizu, Kengo Sumi, Takako Oshiro, Yoshiyuki Yoshinaka, Masaaki Suzuki, Naoki Yamamoto, Leonore A. Herzenberg, Leonard A. Herzenberg, and Masatoshi Hagiwara
Microbiology
- You have accessRegulation of intracellular free calcium concentration during heterocyst differentiation by HetR and NtcA in Anabaena sp. PCC 7120Yunming Shi, Weixing Zhao, Wei Zhang, Zi Ye, and Jindong Zhao
- You have accessRegulatory protein that inhibits both synthesis and use of the target protein controls flagellar phase variation in Salmonella entericaPhillip D. Aldridge, Cheng Wu, Joshua Gnerer, Joyce E. Karlinsey, Kelly T. Hughes, and Matthew S. Sachs
- Open AccessDissecting virulence pathways of Mycobacterium tuberculosis through protein–protein associationAmit Singh, Deborah Mai, Ashwani Kumar, and Adrie J. C. Steyn
- You have accessDistinguishing features of δ-proteobacterial genomesSamuel Karlin, Luciano Brocchieri, Jan Mrázek, and Dale Kaiser
- Open AccessElectrically conductive bacterial nanowires produced by Shewanella oneidensis strain MR-1 and other microorganismsYuri A. Gorby, Svetlana Yanina, Jeffrey S. McLean, Kevin M. Rosso, Dianne Moyles, Alice Dohnalkova, Terry J. Beveridge, In Seop Chang, Byung Hong Kim, Kyung Shik Kim, David E. Culley, Samantha B. Reed, Margaret F. Romine, Daad A. Saffarini, Eric A. Hill, Liang Shi, Dwayne A. Elias, David W. Kennedy, Grigoriy Pinchuk, Kazuya Watanabe, Shun’ichi Ishii, Bruce Logan, Kenneth H. Nealson, and Jim K. Fredrickson
- You have accessStructural basis for targeting HIV-1 Gag proteins to the plasma membrane for virus assembly
- From the Cover
Jamil S. Saad, Jaime Miller, Janet Tai, Andrew Kim, Ruba H. Ghanam, and Michael F. SummersSee companion article:
- In This Issue- Jul 25, 2006
- HIV-1 Gag: Flipped out for PI(4,5)P2- Jul 17, 2006
Neuroscience
- Open AccessA form of motor cortical plasticity that correlates with recovery of function after brain injuryDhakshin Ramanathan, James M. Conner, and Mark H. Tuszynski
- You have accessAcid-sensitive ionic channels in midbrain dopamine neurons are sensitive to ammonium, which may contribute to hyperammonemia damageVolodymyr I. Pidoplichko and John A. Dani
- You have accessThe influence of meaning on the perception of speech soundsNina Kazanina, Colin Phillips, and William Idsardi
- You have accessCortical systems mediating visual attention to both objects and spatial locationsSarah Shomstein and Marlene Behrmann
- Open AccessThe cannabinoid WIN 55,212-2 inhibits transient receptor potential vanilloid 1 (TRPV1) and evokes peripheral antihyperalgesia via calcineurinAmol M. Patwardhan, Nathaniel A. Jeske, Theodore J. Price, Nikita Gamper, Armen N. Akopian, and Kenneth M. Hargreaves
- Open AccessFactors regulating the abundance and localization of synaptobrevin in the plasma membraneJeremy S. Dittman and Joshua M. Kaplan
Physiology
- You have accessNonvascular VEGF receptor 3 expression by corneal epithelium maintains avascularity and visionClaus Cursiefen, Lu Chen, Magali Saint-Geniez, Pedram Hamrah, Yiping Jin, Saadia Rashid, Bronislaw Pytowski, Kris Persaud, Yan Wu, J. Wayne Streilein, and Reza Dana
- You have accessBarttin modulates trafficking and function of ClC-K channelsUte Scholl, Simon Hebeisen, Audrey G. H. Janssen, Gerhard Müller-Newen, Alexi Alekov, and Christoph Fahlke
Plant Biology
- You have accessDevelopment and application of a suite of polysaccharide-degrading enzymes for analyzing plant cell walls
- From the Cover
Stefan Bauer, Prasanna Vasu, Staffan Persson, Andrew J. Mort, and Chris R. SomervilleSee companion article:
- In This Issue- Jul 25, 2006
Population Biology
- Open AccessGlobalization and the population structure of Toxoplasma gondii
- From the Cover
Tovi Lehmann, Paula L. Marcet, Doug H. Graham, Erica R. Dahl, and J. P. Dubey
Commentary
See companion article: