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Table of Contents
November 07, 2006; vol. 103 no. 45
This Week in PNAS
- You have accessIn This Issue
See companion article:
- Impacts of genetic bottlenecks on soybean genome diversity- Oct 26, 2006
- Universal scaling for polymer chain scission in turbulence- Oct 30, 2006
Perspective
- You have accessA backbone-based theory of protein foldingGeorge D. Rose, Patrick J. Fleming, Jayanth R. Banavar, and Amos Maritan
Profile
Physical Sciences
Chemistry
- You have accessPhotoprotection of human retinal pigment epithelium cells against blue light-induced apoptosis by melanin free radicals from Sepia officinalisBrandon-Luke L. Seagle, Elzbieta M. Gasyna, William F. Mieler, and James R. Norris Jr.
- You have accessA single dose of doxorubicin-functionalized bow-tie dendrimer cures mice bearing C-26 colon carcinomasCameron C. Lee, Elizabeth R. Gillies, Megan E. Fox, Steven J. Guillaudeu, Jean M. J. Fréchet, Edward E. Dy, and Francis C. Szoka
- You have accessPhotoreactivation of DNA by an Archaeal nucleoprotein Sso7dRyu Tashiro, Andrew H.-J. Wang, and Hiroshi Sugiyama
Engineering
- You have accessUniversal scaling for polymer chain scission in turbulenceSiva A. Vanapalli, Steven L. Ceccio, and Michael J. Solomon
See companion article:
- In This Issue- Nov 07, 2006
Geology
- You have accessConfirmation of Romer's Gap as a low oxygen interval constraining the timing of initial arthropod and vertebrate terrestrializationPeter Ward, Conrad Labandeira, Michel Laurin, and Robert A. Berner
Medical Sciences
- You have accessCardiac myosin binding protein c phosphorylation is cardioprotectiveSakthivel Sadayappan, Hanna Osinska, Raisa Klevitsky, John N. Lorenz, Michelle Sargent, Jeffrey D. Molkentin, Christine E. Seidman, Jonathan G. Seidman, and Jeffrey Robbins
Social Sciences
Psychology
- You have accessA gender- and sexual orientation-dependent spatial attentional effect of invisible imagesYi Jiang, Patricia Costello, Fang Fang, Miner Huang, and Sheng He
- You have accessDay-to-day dynamics of experience–cortisol associations in a population-based sample of older adultsEmma K. Adam, Louise C. Hawkley, Brigitte M. Kudielka, and John T. Cacioppo
Sustainability Science
- You have accessPolicy strategies to address sustainability of Alaskan boreal forests in response to a directionally changing climate
- Inaugural Article
F. Stuart Chapin III, Amy L. Lovecraft, Erika S. Zavaleta, Joanna Nelson, Martin D. Robards, Gary P. Kofinas, Sarah F. Trainor, Garry D. Peterson, Henry P. Huntington, and Rosamond L. NaylorSee companion article:
- Profile of F. Stuart Chapin III- Oct 31, 2006
Biological Sciences
Agricultural Sciences
- Open AccessImpacts of genetic bottlenecks on soybean genome diversityDavid L. Hyten, Qijian Song, Youlin Zhu, Ik-Young Choi, Randall L. Nelson, Jose M. Costa, James E. Specht, Randy C. Shoemaker, and Perry B. Cregan
See companion article:
- In This Issue- Nov 07, 2006
- You have accessChanging green leaf volatile biosynthesis in plants: An approach for improving plant resistance against both herbivores and pathogensKaori Shiojiri, Kyutaro Kishimoto, Rika Ozawa, Soichi Kugimiya, Soichi Urashimo, Genichiro Arimura, Junichiro Horiuchi, Takaaki Nishioka, Kenji Matsui, and Junji Takabayashi
Applied Biological Sciences
- Open AccessSingle-step electronic detection of femtomolar DNA by target-induced strand displacement in an electrode-bound duplexYi Xiao, Arica A. Lubin, Brian R. Baker, Kevin W. Plaxco, and Alan J. Heeger
- You have accessA neuroinductive biomaterial based on dopamineJin Gao, Yu Mi Kim, Herna Coe, Blaine Zern, Barbara Sheppard, and Yadong Wang
Biochemistry
- You have accessThe 39-kDa poly(ADP-ribose) glycohydrolase ARH3 hydrolyzes O-acetyl-ADP-ribose, a product of the Sir2 family of acetyl-histone deacetylasesTohru Ono, Atsushi Kasamatsu, Shunya Oka, and Joel Moss
- Open AccessA Ras-induced conformational switch in the Ras activator Son of sevenlessTanya S. Freedman, Holger Sondermann, Gregory D. Friedland, Tanja Kortemme, Dafna Bar-Sagi, Susan Marqusee, and John Kuriyan
- You have accessNonspecific binding to structured RNA and preferential unwinding of an exposed helix by the CYT-19 protein, a DEAD-box RNA chaperonePilar Tijerina, Hari Bhaskaran, and Rick Russell
- You have accessCoupling of STIM1 to store-operated Ca2+ entry through its constitutive and inducible movement in the endoplasmic reticulumYoshihiro Baba, Kenji Hayashi, Yoko Fujii, Akiko Mizushima, Hiroshi Watarai, Minoru Wakamori, Takuro Numaga, Yasuo Mori, Masamitsu Iino, Masaki Hikida, and Tomohiro Kurosaki
- You have accessCombinatorial methods for small-molecule placement in computational enzyme designJonathan Kyle Lassila, Heidi K. Privett, Benjamin D. Allen, and Stephen L. Mayo
- You have accessHaploinsufficiency of the corepressor of estrogen receptor activity (REA) enhances estrogen receptor function in the mammary glandPaola Mussi, Lan Liao, Seong-Eun Park, Paolo Ciana, Adriana Maggi, Benita S. Katzenellenbogen, Jianming Xu, and Bert W. O'Malley
- You have accessDisulfide cross-linking indicates that FlgM-bound and free σ28 adopt similar conformationsMargareta K. Sorenson and Seth A. Darst
- You have accessIdentification of a starter unit acyl-carrier protein transacylase domain in an iterative type I polyketide synthaseJason M. Crawford, Blair C. R. Dancy, Eric A. Hill, Daniel W. Udwary, and Craig A. Townsend
Biophysics
- You have accessNonlinear auditory mechanism enhances female sounds for male mosquitoes
- From the Cover
Joseph C. Jackson and Daniel RobertSee companion article:
- A boost for hearing in mosquitoes- Oct 30, 2006
- In This Issue- Nov 07, 2006
- You have accessAmide vibrations are delocalized across the hydrophobic interface of a transmembrane helix dimerChong Fang, Alessandro Senes, Lidia Cristian, William F. DeGrado, and Robin M. Hochstrasser
- You have accessPhase knowledge enables rational screens for protein crystallizationMegan J. Anderson, Carl L. Hansen, and Stephen R. Quake
- You have accessStatistics of cellular signal transduction as a race to the nucleus by multiple random walkers in compartment/phosphorylation spaceTing Lu, Tongye Shen, Chenghang Zong, Jeff Hasty, and Peter G. Wolynes
- You have accessModeling dual pathways for the metazoan spindle assembly checkpointRichard P. Sear and Martin Howard
- Open AccessFluorescence correlation spectroscopy shows that monomeric polyglutamine molecules form collapsed structures in aqueous solutionsScott L. Crick, Murali Jayaraman, Carl Frieden, Ronald Wetzel, and Rohit V. Pappu
Cell Biology
- You have accessAn in vitro assay reveals a role for the diaphragm protein PV-1 in endothelial fenestra morphogenesis
- From the Cover
Sofia Ioannidou, Katrin Deinhardt, Jadwiga Miotla, John Bradley, Eunice Cheung, Steven Samuelsson, Yin-Shan Ng, and David T. Shima - You have accessEssential role of RGS-PX1/sorting nexin 13 in mouse development and regulation of endocytosis dynamicsBin Zheng, Tingdong Tang, Nan Tang, Krystyna Kudlicka, Kazuaki Ohtsubo, Phuong Ma, Jamey D. Marth, Marilyn G. Farquhar, and Eero Lehtonen
Developmental Biology
- Open AccessSome C. elegans class B synthetic multivulva proteins encode a conserved LIN-35 Rb-containing complex distinct from a NuRD-like complexMelissa M. Harrison, Craig J. Ceol, Xiaowei Lu, and H. Robert Horvitz
- You have accessMolecular interactions between Tbx3 and Bmp4 and a model for dorsoventral positioning of mammary gland developmentKyoung-Won Cho, Jae-Young Kim, Soo-Jin Song, Elizabeth Farrell, Maxwell C. Eblaghie, Hee-Jin Kim, Cheryll Tickle, and Han-Sung Jung
- You have accessMutation of TweedleD, a member of an unconventional cuticle protein family, alters body shape in DrosophilaXiao Guan, Brooke W. Middlebrooks, Sherry Alexander, and Steven A. Wasserman
- You have accessVertebrate MAX-1 is required for vascular patterning in zebrafishHanbing Zhong, Xinrong Wu, Haigen Huang, Qichang Fan, Zuoyan Zhu, and Shuo Lin
- You have accessWnt and TGF-β signaling are required for the induction of an in vitro model of primitive streak formation using embryonic stem cellsPaul Gadue, Tara L. Huber, Patrick J. Paddison, and Gordon M. Keller
See companion article:
- In This Issue- Nov 07, 2006
Ecology
- You have accessModern Quaternary plant lineages promote diversity through facilitation of ancient Tertiary lineagesAlfonso Valiente-Banuet, Adolfo Vital Rumebe, Miguel Verdú, and Ragan M. Callaway
Evolution
- You have accessConfirmation of Romer's Gap as a low oxygen interval constraining the timing of initial arthropod and vertebrate terrestrializationPeter Ward, Conrad Labandeira, Michel Laurin, and Robert A. Berner
- You have accessHagfish and lancelet fibrillar collagens reveal that type II collagen-based cartilage evolved in stem vertebratesGuangJun Zhang and Martin J. Cohn
Genetics
- You have accessA genetic variant that disrupts MET transcription is associated with autismDaniel B. Campbell, James S. Sutcliffe, Philip J. Ebert, Roberto Militerni, Carmela Bravaccio, Simona Trillo, Maurizio Elia, Cindy Schneider, Raun Melmed, Roberto Sacco, Antonio M. Persico, and Pat Levitt
See companion article:
- In This Issue- Nov 07, 2006
- You have accessTemplate disruptions and failure of double Holliday junction dissolution during double-strand break repair in Drosophila BLM mutantsDena Johnson-Schlitz and William R. Engels
Immunology
- You have accessQuantum dot/peptide-MHC biosensors reveal strong CD8-dependent cooperation between self and viral antigens that augment the T cell responseNadia Anikeeva, Tatiana Lebedeva, Aaron R. Clapp, Ellen R. Goldman, Michael L. Dustin, Hedi Mattoussi, and Yuri Sykulev
- You have accessResponses of IL-18- and IL-18 receptor-deficient pancreatic islets with convergence of positive and negative signals for the IL-18 receptorEli C. Lewis and Charles A. Dinarello
- You have accessIncreased melanizing activity in Anopheles gambiae does not affect development of Plasmodium falciparumKristin Michel, Chansak Suwanchaichinda, Isabelle Morlais, Louis Lambrechts, Anna Cohuet, Parfait H. Awono-Ambene, Frederic Simard, Didier Fontenille, Michael R. Kanost, and Fotis C. Kafatos
Medical Sciences
- You have accessPhotoprotection of human retinal pigment epithelium cells against blue light-induced apoptosis by melanin free radicals from Sepia officinalisBrandon-Luke L. Seagle, Elzbieta M. Gasyna, William F. Mieler, and James R. Norris Jr.
- Open AccessFibrosis, not cell size, delineates β-myosin heavy chain reexpression during cardiac hypertrophy and normal aging in vivoKumar Pandya, Hyung-Suk Kim, and Oliver Smithies
- Open AccessTargeting multiple kinase pathways in leukemic progenitors and stem cells is essential for improved treatment of Ph+ leukemia in miceYiguo Hu, Sarah Swerdlow, Theodore M. Duffy, Roberto Weinmann, Francis Y. Lee, and Shaoguang Li
- You have accessDepression induces bone loss through stimulation of the sympathetic nervous system
- From the Cover
Raz Yirmiya, Inbal Goshen, Alon Bajayo, Tirzah Kreisel, Sharon Feldman, Joseph Tam, Victoria Trembovler, Valér Csernus, Esther Shohami, and Itai Bab - You have accessSjögren's syndrome-like disease in mice with T cells lacking class 1A phosphoinositide-3-kinaseJean S. Oak, Jonathan A. Deane, Michael G. Kharas, Ji Luo, Thomas E. Lane, Lewis C. Cantley, and David A. Fruman
- You have accessCLA-1 and its splicing variant CLA-2 mediate bacterial adhesion and cytosolic bacterial invasion in mammalian cellsTatyana G. Vishnyakova, Roger Kurlander, Alexander V. Bocharov, Irina N. Baranova, Zhigang Chen, Mones S. Abu-Asab, Maria Tsokos, Daniela Malide, Federica Basso, Alan Remaley, Gyorgy Csako, Thomas L. Eggerman, and Amy P. Patterson
- Open AccessInteraction of GATA-3/T-bet transcription factors regulates expression of sialyl Lewis X homing receptors on Th1/Th2 lymphocytesGuo-Yun Chen, Hirotaka Osada, Luis F. Santamaria-Babi, and Reiji Kannagi
- You have accessThe role of platelet adhesion receptor GPIbα far exceeds that of its main ligand, von Willebrand factor, in arterial thrombosisWolfgang Bergmeier, Crystal L. Piffath, Tobias Goerge, Stephen M. Cifuni, Zaverio M. Ruggeri, Jerry Ware, and Denisa D. Wagner
- You have accessAkt1 deficiency affects neuronal morphology and predisposes to abnormalities in prefrontal cortex functioningWen-Sung Lai, Bin Xu, Koen G. C. Westphal, Marta Paterlini, Berend Olivier, Paul Pavlidis, Maria Karayiorgou, and Joseph A. Gogos
- You have accessVitamin C mediates chemical aging of lens crystallins by the Maillard reaction in a humanized mouse modelXingjun Fan, Lixing W. Reneker, Mark E. Obrenovich, Christopher Strauch, Rongzhu Cheng, Simon M. Jarvis, Beryl J. Ortwerth, and Vincent M. Monnier
- You have accessCdx4 dysregulates Hox gene expression and generates acute myeloid leukemia alone and in cooperation with Meis1a in a murine modelDimple Bansal, Claudia Scholl, Stefan Fröhling, Elizabeth McDowell, Benjamin H. Lee, Konstanze Döhner, Patricia Ernst, Alan J. Davidson, George Q. Daley, Leonard I. Zon, D. Gary Gilliland, and Brian J. P. Huntly
- Open AccessExpression of TEL-JAK2 in primary human hematopoietic cells drives erythropoietin-independent erythropoiesis and induces myelofibrosis in vivoJ. A. Kennedy, F. Barabé, B. J. Patterson, J. Bayani, J. A. Squire, D. L. Barber, and J. E. Dick
Microbiology
- You have accessEmergence and predominance of an H5N1 influenza variant in ChinaG. J. D. Smith, X. H. Fan, J. Wang, K. S. Li, K. Qin, J. X. Zhang, D. Vijaykrishna, C. L. Cheung, K. Huang, J. M. Rayner, J. S. M. Peiris, H. Chen, R. G. Webster, and Y. Guan
- You have accessVaccine assembly from surface proteins of Staphylococcus aureusYukiko K. Stranger-Jones, Taeok Bae, and Olaf Schneewind
- You have accessA structurally unrelated mimic of a Pseudomonas aeruginosa acyl-homoserine lactone quorum-sensing signalUte Müh, Brian J. Hare, Breck A. Duerkop, Martin Schuster, Brian L. Hanzelka, Roger Heim, Eric R. Olson, and E. Peter Greenberg
- You have accessLegionella pneumophila glucosyltransferase inhibits host elongation factor 1AYury Belyi, Ricarda Niggeweg, Bastian Opitz, Martin Vogelsgesang, Stefan Hippenstiel, Matthias Wilm, and Klaus Aktories
- Open AccessGeneration of HIV-1 derivatives that productively infect macaque monkey lymphoid cellsKazuya Kamada, Tatsuhiko Igarashi, Malcolm A. Martin, Boonruang Khamsri, Kazuki Hatcho, Tomoki Yamashita, Mikako Fujita, Tsuneo Uchiyama, and Akio Adachi
Neuroscience
- Open AccessImplications of the quaternary twist allosteric model for the physiology and pathology of nicotinic acetylcholine receptorsAntoine Taly, Pierre-Jean Corringer, Thomas Grutter, Lia Prado de Carvalho, Martin Karplus, and Jean-Pierre Changeux
- You have accessNMDA receptors promote survival in somatosensory relay nuclei by inhibiting Bax-dependent developmental cell deathJuan Carlos de Rivero Vaccari, Gregory P. Casey, Salman Aleem, Won-Mee Park, and Roderick A. Corriveau
- You have accessActivity-dependent gene regulation in skeletal muscle is mediated by a histone deacetylase (HDAC)-Dach2-myogenin signal transduction cascadeHuibin Tang and Daniel Goldman
- You have accessActivation of estrogen receptor α increases and estrogen receptor β decreases apolipoprotein E expression in hippocampus in vitro and in vivoJun Ming Wang, Ronald W. Irwin, and Roberta Diaz Brinton
- You have accessUse of polysialic acid in repair of the central nervous systemAbderrahman El Maarouf, Athanasios K. Petridis, and Urs Rutishauser
- You have accessMyoD expression restores defective myogenic differentiation of human mesoangioblasts from inclusion-body myositis muscleRoberta Morosetti, Massimiliano Mirabella, Carla Gliubizzi, Aldobrando Broccolini, Luciana De Angelis, Enrico Tagliafico, Maurilio Sampaolesi, Teresa Gidaro, Manuela Papacci, Enrica Roncaglia, Sergio Rutella, Stefano Ferrari, Pietro Attilio Tonali, Enzo Ricci, and Giulio Cossu
- Open AccessNavigation-associated medial parietal neurons in monkeysNobuya Sato, Hideo Sakata, Yuji L. Tanaka, and Masato Taira
- Open AccessCognitive enhancement with central thalamic electrical stimulationPrasad Shirvalkar, Malika Seth, Nicholas D. Schiff, and Daniel G. Herrera
- You have accessValence-sensitive neurons exhibit divergent functional profiles in gregarious and asocial speciesJames L. Goodson and Yiwei Wang
Pharmacology
- You have accessA single dose of doxorubicin-functionalized bow-tie dendrimer cures mice bearing C-26 colon carcinomasCameron C. Lee, Elizabeth R. Gillies, Megan E. Fox, Steven J. Guillaudeu, Jean M. J. Fréchet, Edward E. Dy, and Francis C. Szoka
- Open AccessEndothelial cellular senescence is inhibited by nitric oxide: Implications in atherosclerosis associated with menopause and diabetesToshio Hayashi, Hisako Matsui-Hirai, Asaka Miyazaki-Akita, Akiko Fukatsu, Jun Funami, Qun-Fang Ding, Sumitra Kamalanathan, Yuichi Hattori, Louis J. Ignarro, and Akihisa Iguchi
- You have accessAtherosclerosis-related molecular alteration of the human CaV1.2 calcium channel α1C subunitSwasti Tiwari, Yuwei Zhang, Jennifer Heller, Darrell R. Abernethy, and Nikolai M. Soldatov
- Open AccessμO-conotoxin MrVIB selectively blocks Nav1.8 sensory neuron specific sodium channels and chronic pain behavior without motor deficitsJ. Ekberg, A. Jayamanne, C. W. Vaughan, S. Aslan, L. Thomas, J. Mould, R. Drinkwater, M. D. Baker, B. Abrahamsen, J. N. Wood, D. J. Adams, M. J. Christie, and R. J. Lewis
Plant Biology
- You have accessCryptochrome-1-dependent execution of programmed cell death induced by singlet oxygen in Arabidopsis thalianaAntoine Danon, Núria Sánchez Coll, and Klaus Apel
- You have accessCloning of DOG1, a quantitative trait locus controlling seed dormancy in ArabidopsisLeónie Bentsink, Jemma Jowett, Corrie J. Hanhart, and Maarten Koornneef
Psychology
- You have accessA gender- and sexual orientation-dependent spatial attentional effect of invisible imagesYi Jiang, Patricia Costello, Fang Fang, Miner Huang, and Sheng He
- You have accessSelf-recognition in an Asian elephant
- From the Cover
Joshua M. Plotnik, Frans B. M. de Waal, and Diana Reiss
Sustainability Science
- You have accessPolicy strategies to address sustainability of Alaskan boreal forests in response to a directionally changing climate
- Inaugural Article
F. Stuart Chapin III, Amy L. Lovecraft, Erika S. Zavaleta, Joanna Nelson, Martin D. Robards, Gary P. Kofinas, Sarah F. Trainor, Garry D. Peterson, Henry P. Huntington, and Rosamond L. NaylorSee companion article:
- Profile of F. Stuart Chapin III- Oct 31, 2006
Commentaries
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