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Table of Contents

April 03, 2007; vol. 104 no. 14

This Week in PNAS

  • You have access
    In This Issue
    PNAS April 3, 2007 104 (14) 5705-5706; https://doi.org/10.1073/iti1407104

    See companion article:

    • Projected distributions of novel and disappearing climates by 2100 AD
      - Mar 27, 2007
    • Implications for invariant natural killer T cell ligands due to the restricted presence of isoglobotrihexosylceramide in mammals
      - Mar 19, 2007
    • Normal development and function of invariant natural killer T cells in mice with isoglobotrihexosylceramide (iGb3) deficiency
      - Mar 19, 2007
    • Exercise reverses preamyloid oligomer and prolongs survival in αB-crystallin-based desmin-related cardiomyopathy
      - Mar 26, 2007
    • Homogenization of regional river dynamics by dams and global biodiversity implications
      - Mar 12, 2007
    • Hepatitis C virus production by human hepatocytes dependent on assembly and secretion of very low-density lipoproteins
      - Mar 21, 2007

Commentaries

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    Fish extinctions and ecosystem functioning in tropical ecosystems
    Daniel E. Schindler
    PNAS April 3, 2007 104 (14) 5707-5708; https://doi.org/10.1073/pnas.0700426104

    See companion article:

    • Fish extinctions alter nutrient recycling in tropical freshwaters
      - Feb 20, 2007
  • You have access
    Further evidence of the safety of assisted reproductive technologies
    Zev Rosenwaks and Kristin Bendikson
    PNAS April 3, 2007 104 (14) 5709-5710; https://doi.org/10.1073/pnas.0701316104

    See companion article:

    • Assisted reproductive technologies do not alter mutation frequency or spectrum
      - Mar 02, 2007
  • You have access
    Homogenous rivers, homogenous faunas
    Peter B. Moyle and Jeffrey F. Mount
    PNAS April 3, 2007 104 (14) 5711-5712; https://doi.org/10.1073/pnas.0701457104

    See companion article:

    • Homogenization of regional river dynamics by dams and global biodiversity implications
      - Mar 12, 2007
  • You have access
    Natural killer T cells: Know thyself
    Mitchell Kronenberg and Laurent Gapin
    PNAS April 3, 2007 104 (14) 5713-5714; https://doi.org/10.1073/pnas.0701493104

    See companion article:

    • Implications for invariant natural killer T cell ligands due to the restricted presence of isoglobotrihexosylceramide in mammals
      - Mar 19, 2007
    • Normal development and function of invariant natural killer T cells in mice with isoglobotrihexosylceramide (iGb3) deficiency
      - Mar 19, 2007

Physical sciences

  • Environmental sciences

    • You have access
      Homogenization of regional river dynamics by dams and global biodiversity implications
      • From the Cover
      N. LeRoy Poff, Julian D. Olden, David M. Merritt, and David M. Pepin
      PNAS April 3, 2007 104 (14) 5732-5737; https://doi.org/10.1073/pnas.0609812104

      See companion article:

      • In This Issue
        - Apr 03, 2007
      • Homogenous rivers, homogenous faunas
        - Mar 28, 2007

Physical Sciences

  • Applied Physical Sciences

    • You have access
      Micromechanical control of cell–cell interactions
      • From the Cover
      Elliot E. Hui and Sangeeta N. Bhatia
      PNAS April 3, 2007 104 (14) 5722-5726; https://doi.org/10.1073/pnas.0608660104
  • Chemistry

    • Open Access
      High-pressure/low-temperature neutron scattering of gas inclusion compounds: Progress and prospects
      Yusheng Zhao, Hongwu Xu, Luke L. Daemen, Konstantin Lokshin, Kimberly T. Tait, Wendy L. Mao, Junhua Luo, Robert P. Currier, and Donald D. Hickmott
      PNAS April 3, 2007 104 (14) 5727-5731; https://doi.org/10.1073/pnas.0610332104
    • You have access
      Destruction of long-range interactions by a single mutation in lysozyme
      Ruhong Zhou, Maria Eleftheriou, Ajay K. Royyuru, and Bruce J. Berne
      PNAS April 3, 2007 104 (14) 5824-5829; https://doi.org/10.1073/pnas.0701249104
  • Environmental Sciences

    • You have access
      Projected distributions of novel and disappearing climates by 2100 AD
      John W. Williams, Stephen T. Jackson, and John E. Kutzbach
      PNAS April 3, 2007 104 (14) 5738-5742; https://doi.org/10.1073/pnas.0606292104

      See companion article:

      • In This Issue
        - Apr 03, 2007
    • You have access
      20th-Century doubling in dust archived in an Antarctic Peninsula ice core parallels climate change and desertification in South America
      Joseph R. McConnell, Alberto J. Aristarain, J. Ryan Banta, P. Ross Edwards, and Jefferson C. Simões
      PNAS April 3, 2007 104 (14) 5743-5748; https://doi.org/10.1073/pnas.0607657104
  • Geophysics

    • Open Access
      Thermodynamic constraints on stochastic acceleration in compressional turbulence
      Lennard A. Fisk and George Gloeckler
      PNAS April 3, 2007 104 (14) 5749-5754; https://doi.org/10.1073/pnas.0700881104
  • Physics

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      Estimation of critical exponents from cluster coefficients and the application of this estimation to hard spheres
      E. Eisenberg and A. Baram
      PNAS April 3, 2007 104 (14) 5755-5758; https://doi.org/10.1073/pnas.0700778104

Biological Sciences

  • Biochemistry

    • Open Access
      Abscisic acid is an endogenous cytokine in human granulocytes with cyclic ADP-ribose as second messenger
      Santina Bruzzone, Iliana Moreschi, Cesare Usai, Lucrezia Guida, Gianluca Damonte, Annalisa Salis, Sonia Scarfì, Enrico Millo, Antonio De Flora, and Elena Zocchi
      PNAS April 3, 2007 104 (14) 5759-5764; https://doi.org/10.1073/pnas.0609379104
    • You have access
      The p23 molecular chaperone promotes functional telomerase complexes through DNA dissociation
      Oyetunji A. Toogun, Will Zeiger, and Brian C. Freeman
      PNAS April 3, 2007 104 (14) 5765-5770; https://doi.org/10.1073/pnas.0701442104
    • Open Access
      Coordinate expression and functional profiling identify an extracellular proteolytic signaling pathway
      Ami S. Bhatt, Alana Welm, Christopher J. Farady, Maximiliano Vásquez, Keith Wilson, and Charles S. Craik
      PNAS April 3, 2007 104 (14) 5771-5776; https://doi.org/10.1073/pnas.0606514104
    • You have access
      Structural basis for the selection of glycosylated substrates by SCFFbs1 ubiquitin ligase
      Tsunehiro Mizushima, Yukiko Yoshida, Taichi Kumanomidou, Yuko Hasegawa, Atsuo Suzuki, Takashi Yamane, and Keiji Tanaka
      PNAS April 3, 2007 104 (14) 5777-5781; https://doi.org/10.1073/pnas.0610312104
    • You have access
      Structural insight into substrate specificity of phosphodiesterase 10
      • From the Cover
      Huanchen Wang, Yudong Liu, Jing Hou, Meiyan Zheng, Howard Robinson, and Hengming Ke
      PNAS April 3, 2007 104 (14) 5782-5787; https://doi.org/10.1073/pnas.0700279104
    • Open Access
      Reconfiguration of yeast 40S ribosomal subunit domains by the translation initiation multifactor complex
      Robert J. C. Gilbert, Yulya Gordiyenko, Tobias von der Haar, Andreas F.-P. Sonnen, Gregor Hofmann, Maria Nardelli, David I. Stuart, and John E. G. McCarthy
      PNAS April 3, 2007 104 (14) 5788-5793; https://doi.org/10.1073/pnas.0606880104
    • You have access
      Estrogen receptor α is a putative substrate for the BRCA1 ubiquitin ligase
      Catherine M. Eakin, Michael J. MacCoss, Gregory L. Finney, and Rachel E. Klevit
      PNAS April 3, 2007 104 (14) 5794-5799; https://doi.org/10.1073/pnas.0610887104
    • You have access
      Interdomain communication in calcium pump as revealed in the crystal structures with transmembrane inhibitors
      Mihoko Takahashi, Youhei Kondou, and Chikashi Toyoshima
      PNAS April 3, 2007 104 (14) 5800-5805; https://doi.org/10.1073/pnas.0700979104
    • You have access
      Extrachromosomal element capture and the evolution of multiple replication origins in archaeal chromosomes
      Nicholas P. Robinson and Stephen D. Bell
      PNAS April 3, 2007 104 (14) 5806-5811; https://doi.org/10.1073/pnas.0700206104
    • You have access
      Chemical inhibition of the TFIIH-associated kinase Cdk7/Kin28 does not impair global mRNA synthesis
      Elenita I. Kanin, Ryan T. Kipp, Charles Kung, Matthew Slattery, Agnes Viale, Steven Hahn, Kevan M. Shokat, and Aseem Z. Ansari
      PNAS April 3, 2007 104 (14) 5812-5817; https://doi.org/10.1073/pnas.0611505104
    • You have access
      Evidence for proton transfer in the rate-limiting step of a fast-cleaving Varkud satellite ribozyme
      M. Duane Smith and Richard A. Collins
      PNAS April 3, 2007 104 (14) 5818-5823; https://doi.org/10.1073/pnas.0608864104
  • Biophysics

    • You have access
      Destruction of long-range interactions by a single mutation in lysozyme
      Ruhong Zhou, Maria Eleftheriou, Ajay K. Royyuru, and Bruce J. Berne
      PNAS April 3, 2007 104 (14) 5824-5829; https://doi.org/10.1073/pnas.0701249104
    • Open Access
      Correlation between mechanical strength of messenger RNA pseudoknots and ribosomal frameshifting
      Thomas M. Hansen, S. Nader S. Reihani, Lene B. Oddershede, and Michael A. Sørensen
      PNAS April 3, 2007 104 (14) 5830-5835; https://doi.org/10.1073/pnas.0608668104
  • Cell Biology

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      CCR4/NOT complex associates with the proteasome and regulates histone methylation
      R. Nicholas Laribee, Yoichiro Shibata, Douglas P. Mersman, Sean R. Collins, Patrick Kemmeren, Assen Roguev, Jonathan S. Weissman, Scott D. Briggs, Nevan J. Krogan, and Brian D. Strahl
      PNAS April 3, 2007 104 (14) 5836-5841; https://doi.org/10.1073/pnas.0607996104
    • You have access
      Unc-51-like kinase 1/2-mediated endocytic processes regulate filopodia extension and branching of sensory axons
      Xiang Zhou, J. Ramesh Babu, Susana da Silva, Qing Shu, Isabella A. Graef, Tim Oliver, Toshifumi Tomoda, Tomomi Tani, Marie W. Wooten, and Fan Wang
      PNAS April 3, 2007 104 (14) 5842-5847; https://doi.org/10.1073/pnas.0701402104
    • Open Access
      Hepatitis C virus production by human hepatocytes dependent on assembly and secretion of very low-density lipoproteins
      • From the Cover
      Hua Huang, Fang Sun, David M. Owen, Weiping Li, Yan Chen, Michael Gale Jr., and Jin Ye
      PNAS April 3, 2007 104 (14) 5848-5853; https://doi.org/10.1073/pnas.0700760104

      See companion article:

      • In This Issue
        - Apr 03, 2007
    • You have access
      Morlin, an inhibitor of cortical microtubule dynamics and cellulose synthase movement
      Seth DeBolt, Ryan Gutierrez, David W. Ehrhardt, Carlos V. Melo, Loretta Ross, Sean R. Cutler, Christopher Somerville, and Dario Bonetta
      PNAS April 3, 2007 104 (14) 5854-5859; https://doi.org/10.1073/pnas.0700789104
    • You have access
      Multiple reaction monitoring for robust quantitative proteomic analysis of cellular signaling networks
      Alejandro Wolf-Yadlin, Sampsa Hautaniemi, Douglas A. Lauffenburger, and Forest M. White
      PNAS April 3, 2007 104 (14) 5860-5865; https://doi.org/10.1073/pnas.0608638104
    • You have access
      Signaling-dependent and coordinated regulation of transcription, splicing, and translation resides in a single coregulator, PCBP1
      Qingchang Meng, Suresh K. Rayala, Anupama E. Gururaj, Amjad H. Talukder, Bert W. O'Malley, and Rakesh Kumar
      PNAS April 3, 2007 104 (14) 5866-5871; https://doi.org/10.1073/pnas.0701065104
    • Open Access
      Rab27b regulates number and secretion of platelet dense granules
      Tanya Tolmachova, Magnus Åbrink, Clare E. Futter, Kalwant S. Authi, and Miguel C. Seabra
      PNAS April 3, 2007 104 (14) 5872-5877; https://doi.org/10.1073/pnas.0609879104
    • Open Access
      Identification of a new intrinsically timed developmental checkpoint that reprograms key hematopoietic stem cell properties
      Michelle B. Bowie, David G. Kent, Brad Dykstra, Kristen D. McKnight, Lindsay McCaffrey, Pamela A. Hoodless, and Connie J. Eaves
      PNAS April 3, 2007 104 (14) 5878-5882; https://doi.org/10.1073/pnas.0700460104
    • You have access
      Molecular and electrophysiological characterization of a mechanosensitive channel expressed in the chloroplasts of Chlamydomonas
      Yoshitaka Nakayama, Kenta Fujiu, Masahiro Sokabe, and Kenjiro Yoshimura
      PNAS April 3, 2007 104 (14) 5883-5888; https://doi.org/10.1073/pnas.0609996104
    • You have access
      Elucidation of intracellular recycling pathways leading to exocytosis of the Fc receptor, FcRn, by using multifocal plane microscopy
      Prashant Prabhat, Zhuo Gan, Jerry Chao, Sripad Ram, Carlos Vaccaro, Steven Gibbons, Raimund J. Ober, and E. Sally Ward
      PNAS April 3, 2007 104 (14) 5889-5894; https://doi.org/10.1073/pnas.0700337104
  • Developmental Biology

    • Open Access
      Melanomas require HEDGEHOG-GLI signaling regulated by interactions between GLI1 and the RAS-MEK/AKT pathways
      Barbara Stecca, Christophe Mas, Virginie Clement, Marie Zbinden, Rafael Correa, Vincent Piguet, Friedrich Beermann, and Ariel Ruiz i Altaba
      PNAS April 3, 2007 104 (14) 5895-5900; https://doi.org/10.1073/pnas.0700776104
    • You have access
      nanos function is essential for development and regeneration of planarian germ cells
      Yuying Wang, Ricardo M. Zayas, Tingxia Guo, and Phillip A. Newmark
      PNAS April 3, 2007 104 (14) 5901-5906; https://doi.org/10.1073/pnas.0609708104
    • You have access
      Cranial muscle defects of Pitx2 mutants result from specification defects in the first branchial arch
      Hung Ping Shih, Michael K. Gross, and Chrissa Kioussi
      PNAS April 3, 2007 104 (14) 5907-5912; https://doi.org/10.1073/pnas.0701122104
    • Open Access
      Jagged-mediated Notch signaling maintains proliferating neural progenitors and regulates cell diversity in the ventral spinal cord
      Sang-Yeob Yeo and Ajay B. Chitnis
      PNAS April 3, 2007 104 (14) 5913-5918; https://doi.org/10.1073/pnas.0607062104
    • You have access
      Crucial roles of Foxa2 in mouse anterior–posterior axis polarization via regulation of anterior visceral endoderm-specific genes
      Chiharu Kimura-Yoshida, E. Tian, Hiroshi Nakano, Saori Amazaki, Kayo Shimokawa, Janet Rossant, Shinichi Aizawa, and Isao Matsuo
      PNAS April 3, 2007 104 (14) 5919-5924; https://doi.org/10.1073/pnas.0607779104
  • Ecology

    • You have access
      Homogenization of regional river dynamics by dams and global biodiversity implications
      • From the Cover
      N. LeRoy Poff, Julian D. Olden, David M. Merritt, and David M. Pepin
      PNAS April 3, 2007 104 (14) 5732-5737; https://doi.org/10.1073/pnas.0609812104

      See companion article:

      • In This Issue
        - Apr 03, 2007
      • Homogenous rivers, homogenous faunas
        - Mar 28, 2007
    • You have access
      Projected distributions of novel and disappearing climates by 2100 AD
      John W. Williams, Stephen T. Jackson, and John E. Kutzbach
      PNAS April 3, 2007 104 (14) 5738-5742; https://doi.org/10.1073/pnas.0606292104

      See companion article:

      • In This Issue
        - Apr 03, 2007
    • You have access
      Global patterns and determinants of vascular plant diversity
      Holger Kreft and Walter Jetz
      PNAS April 3, 2007 104 (14) 5925-5930; https://doi.org/10.1073/pnas.0608361104
    • You have access
      Coarse-grained analysis of stochasticity-induced switching between collective motion states
      Allison Kolpas, Jeff Moehlis, and Ioannis G. Kevrekidis
      PNAS April 3, 2007 104 (14) 5931-5935; https://doi.org/10.1073/pnas.0608270104
  • Evolution

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      High-resolution species trees without concatenation
      Scott V. Edwards, Liang Liu, and Dennis K. Pearl
      PNAS April 3, 2007 104 (14) 5936-5941; https://doi.org/10.1073/pnas.0607004104
    • You have access
      Transgenerational epigenetic imprints on mate preference
      David Crews, Andrea C. Gore, Timothy S. Hsu, Nygerma L. Dangleben, Michael Spinetta, Timothy Schallert, Matthew D. Anway, and Michael K. Skinner
      PNAS April 3, 2007 104 (14) 5942-5946; https://doi.org/10.1073/pnas.0610410104
  • Genetics

    • You have access
      Regulation of Caenorhabditis elegans lifespan by a proteasomal E3 ligase complex
      Arjumand Ghazi, Sivan Henis-Korenblit, and Cynthia Kenyon
      PNAS April 3, 2007 104 (14) 5947-5952; https://doi.org/10.1073/pnas.0700638104
    • You have access
      Riboflavin activated by ultraviolet A1 irradiation induces oxidative DNA damage-mediated mutations inhibited by vitamin C
      Ahmad Besaratinia, Sang-in Kim, Steven E. Bates, and Gerd P. Pfeifer
      PNAS April 3, 2007 104 (14) 5953-5958; https://doi.org/10.1073/pnas.0610534104
    • Open Access
      Metagene projection for cross-platform, cross-species characterization of global transcriptional states
      Pablo Tamayo, Daniel Scanfeld, Benjamin L. Ebert, Michael A. Gillette, Charles W. M. Roberts, and Jill P. Mesirov
      PNAS April 3, 2007 104 (14) 5959-5964; https://doi.org/10.1073/pnas.0701068104
    • You have access
      Meiotic recombination-related DNA synthesis and its implications for cross-over and non-cross-over recombinant formation
      Masahiro Terasawa, Hideyuki Ogawa, Yasumasa Tsukamoto, Miki Shinohara, Katsuhiko Shirahige, Nancy Kleckner, and Tomoko Ogawa
      PNAS April 3, 2007 104 (14) 5965-5970; https://doi.org/10.1073/pnas.0611490104
  • Immunology

    • You have access
      Implications for invariant natural killer T cell ligands due to the restricted presence of isoglobotrihexosylceramide in mammals
      • From the Cover
      Anneliese O. Speak, Mariolina Salio, David C. A. Neville, Josette Fontaine, David A. Priestman, Nick Platt, Tanya Heare, Terry D. Butters, Raymond A. Dwek, Francois Trottein, Mark A. Exley, Vincenzo Cerundolo, and Frances M. Platt
      PNAS April 3, 2007 104 (14) 5971-5976; https://doi.org/10.1073/pnas.0607285104

      See companion article:

      • In This Issue
        - Apr 03, 2007
      • Natural killer T cells: Know thyself
        - Mar 27, 2007
    • You have access
      Normal development and function of invariant natural killer T cells in mice with isoglobotrihexosylceramide (iGb3) deficiency
      • From the Cover
      Stefan Porubsky, Anneliese O. Speak, Bruno Luckow, Vincenzo Cerundolo, Frances M. Platt, and Hermann-Josef Gröne
      PNAS April 3, 2007 104 (14) 5977-5982; https://doi.org/10.1073/pnas.0611139104

      See companion article:

      • Natural killer T cells: Know thyself
        - Mar 27, 2007
      • In This Issue
        - Apr 03, 2007
    • You have access
      Folding of an MHC class II-restricted tumor antigen controls its antigenicity via MHC-guided processing
      Yusuke Mimura, Yuka Mimura-Kimura, Katie Doores, Denise Golgher, Benjamin G. Davis, Raymond A. Dwek, Pauline M. Rudd, and Tim Elliott
      PNAS April 3, 2007 104 (14) 5983-5988; https://doi.org/10.1073/pnas.0701307104
    • You have access
      Costimulatory ligand CD70 is delivered to the immunological synapse by shared intracellular trafficking with MHC class II molecules
      Anna M. Keller, Tom A. Groothuis, Elise A. M. Veraar, Marije Marsman, Lucas Maillette de Buy Wenniger, Hans Janssen, Jacques Neefjes, and Jannie Borst
      PNAS April 3, 2007 104 (14) 5989-5994; https://doi.org/10.1073/pnas.0700946104
  • Medical Sciences

    • You have access
      Exercise reverses preamyloid oligomer and prolongs survival in αB-crystallin-based desmin-related cardiomyopathy
      Alina Maloyan, James Gulick, Charles G. Glabe, Rakez Kayed, and Jeffrey Robbins
      PNAS April 3, 2007 104 (14) 5995-6000; https://doi.org/10.1073/pnas.0609202104

      See companion article:

      • In This Issue
        - Apr 03, 2007
    • You have access
      Ott1(Rbm15) has pleiotropic roles in hematopoietic development
      Glen D. Raffel, Thomas Mercher, Hirokazu Shigematsu, Ifor R. Williams, Dana E. Cullen, Koichi Akashi, Olivier A. Bernard, and D. Gary Gilliland
      PNAS April 3, 2007 104 (14) 6001-6006; https://doi.org/10.1073/pnas.0609041104
    • Open Access
      Correction of prototypic ATM splicing mutations and aberrant ATM function with antisense morpholino oligonucleotides
      Liutao Du, Julianne M. Pollard, and Richard A. Gatti
      PNAS April 3, 2007 104 (14) 6007-6012; https://doi.org/10.1073/pnas.0608616104
    • You have access
      Timing of estrogen therapy after ovariectomy dictates the efficacy of its neuroprotective and antiinflammatory actions
      Shotaro Suzuki, Candice M. Brown, Christopher D. Dela Cruz, Enhua Yang, David A. Bridwell, and Phyllis M. Wise
      PNAS April 3, 2007 104 (14) 6013-6018; https://doi.org/10.1073/pnas.0610394104
    • You have access
      Toll-like receptor-MyD88 and Fc receptor pathways of mast cells mediate the thyroid dysfunctions observed during nonthyroidal illness
      Roberto Rocchi, Hiroaki Kimura, Shey-Cherng Tzou, Koichi Suzuki, Noel R. Rose, Aldo Pinchera, Paul W. Ladenson, and Patrizio Caturegli
      PNAS April 3, 2007 104 (14) 6019-6024; https://doi.org/10.1073/pnas.0701319104
    • You have access
      Rapid induction of virus-neutralizing antibodies and viral clearance in a single-source outbreak of hepatitis C
      Jan M. Pestka, Mirjam B. Zeisel, Edith Bläser, Peter Schürmann, Birke Bartosch, Francois-Loïc Cosset, Arvind H. Patel, Helga Meisel, Jens Baumert, Sergei Viazov, Kay Rispeter, Hubert E. Blum, Michael Roggendorf, and Thomas F. Baumert
      PNAS April 3, 2007 104 (14) 6025-6030; https://doi.org/10.1073/pnas.0607026104
  • Microbiology

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      Lysosomal killing of Mycobacterium mediated by ubiquitin-derived peptides is enhanced by autophagy
      Sylvie Alonso, Kevin Pethe, David G. Russell, and Georgiana E. Purdy
      PNAS April 3, 2007 104 (14) 6031-6036; https://doi.org/10.1073/pnas.0700036104
    • Open Access
      In vivo negative selection screen identifies genes required for Francisella virulence
      David S. Weiss, Anna Brotcke, Thomas Henry, Jeffrey J. Margolis, Kaman Chan, and Denise M. Monack
      PNAS April 3, 2007 104 (14) 6037-6042; https://doi.org/10.1073/pnas.0609675104
    • You have access
      Combinatorial transcriptional control of the lactose operon of Escherichia coli
      Thomas Kuhlman, Zhongge Zhang, Milton H. Saier Jr., and Terence Hwa
      PNAS April 3, 2007 104 (14) 6043-6048; https://doi.org/10.1073/pnas.0606717104
    • Open Access
      Viral activation and recruitment of metacaspases in the unicellular coccolithophore, Emiliania huxleyi
      Kay D. Bidle, Liti Haramaty, Joana Barcelos e Ramos, and Paul Falkowski
      PNAS April 3, 2007 104 (14) 6049-6054; https://doi.org/10.1073/pnas.0701240104
  • Neuroscience

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      Homer 1a uncouples metabotropic glutamate receptor 5 from postsynaptic effectors
      Paul J. Kammermeier and Paul F. Worley
      PNAS April 3, 2007 104 (14) 6055-6060; https://doi.org/10.1073/pnas.0608991104
    • You have access
      Naloxone acts as a potent analgesic in transgenic mouse models of sickle cell anemia
      Mary M. Lunzer, Ajay Yekkirala, Robert P. Hebbel, and Philip S. Portoghese
      PNAS April 3, 2007 104 (14) 6061-6065; https://doi.org/10.1073/pnas.0700295104
    • You have access
      Neural encoding of the concept of nest in the mouse brain
      Longnian Lin, Guifen Chen, Hui Kuang, Dong Wang, and Joe Z. Tsien
      PNAS April 3, 2007 104 (14) 6066-6071; https://doi.org/10.1073/pnas.0701106104
    • You have access
      Overexpression of CCS in G93A-SOD1 mice leads to accelerated neurological deficits with severe mitochondrial pathology
      Marjatta Son, Krishna Puttaparthi, Hibiki Kawamata, Bhagya Rajendran, Philip J. Boyer, Giovanni Manfredi, and Jeffrey L. Elliott
      PNAS April 3, 2007 104 (14) 6072-6077; https://doi.org/10.1073/pnas.0610923104
    • You have access
      Cytosolic phospholipase A2 alpha mediates electrophysiologic responses of hippocampal pyramidal neurons to neurotoxic NMDA treatment
      Ying Shen, Koji Kishimoto, David J. Linden, and Adam Sapirstein
      PNAS April 3, 2007 104 (14) 6078-6083; https://doi.org/10.1073/pnas.0605427104
  • Pharmacology

    • Open Access
      Administration in non-human primates of escalating intravenous doses of targeted nanoparticles containing ribonucleotide reductase subunit M2 siRNA
      • Inaugural Article
      Jeremy D. Heidel, Zhongping Yu, Joanna Yi-Ching Liu, Shyam M. Rele, Yongchao Liang, Ryan K. Zeidan, Douglas J. Kornbrust, and Mark E. Davis
      PNAS April 3, 2007 104 (14) 5715-5721; https://doi.org/10.1073/pnas.0701458104
  • Psychology

    • You have access
      Genomic imprinting mediates sexual experience-dependent olfactory learning in male mice
      William T. Swaney, James P. Curley, Frances A. Champagne, and Eric B. Keverne
      PNAS April 3, 2007 104 (14) 6084-6089; https://doi.org/10.1073/pnas.0609471104
  • Sustainability Science

    • You have access
      Homogenization of regional river dynamics by dams and global biodiversity implications
      • From the Cover
      N. LeRoy Poff, Julian D. Olden, David M. Merritt, and David M. Pepin
      PNAS April 3, 2007 104 (14) 5732-5737; https://doi.org/10.1073/pnas.0609812104

      See companion article:

      • In This Issue
        - Apr 03, 2007
      • Homogenous rivers, homogenous faunas
        - Mar 28, 2007

Corrections

  • You have access
    Correction for Moehle et al., Targeted gene addition into a specified location in the human genome using designed zinc finger nucleases
    PNAS April 3, 2007 104 (14) 6090; https://doi.org/10.1073/pnas.0701949104
  • You have access
    Correction for Manuelidis et al., Cells infected with scrapie and Creutzfeldt–Jakob disease agents produce intracellular 25-nm virus-like particles
    PNAS April 3, 2007 104 (14) 6090; https://doi.org/10.1073/pnas.0701775104
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Proceedings of the National Academy of Sciences: 104 (14)
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