Better explicating the strengths and shortcomings of these models will help refine projections and improve transparency in the years ahead.
Image credit: Witsawat.S.
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Communicated by Darwin J. Prockop, Tulane University, New Orleans, LA, May 16, 2007 (received for review April 3, 2007)
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Article Information
PubMed:
Published By:
Print ISSN:
Online ISSN:
History:
- Published in issue June 26, 2007.
- Published first June 14, 2007.
Copyright & Usage:
© 2007 by The National Academy of Sciences of the USA
Freely available online through the PNAS open access option.
Author Information
- Luis A. Ortiz *,
- Maria DuTreil † ,
- Cheryl Fattman *,
- Amitabh C. Pandey † ,
- German Torres *,
- Kristina Go *, and
- Donald G. Phinney † , ‡
- *Department of Environmental and Occupational Health, University of Pittsburgh, Pittsburgh, PA 15261;
- †Center for Gene Therapy, Tulane University Health Sciences Center, New Orleans, LA 70112
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Communicated by Darwin J. Prockop, Tulane University, New Orleans, LA, May 16, 2007 (received for review April 3, 2007)
Footnotes
- ‡To whom correspondence should be addressed. E-mail: dphinne{at}tulane.edu
-
Author contributions: L.A.O. and D.G.P. designed research; L.A.O., M.D., C.F., A.C.P., G.T., K.G., and D.G.P. performed research; L.A.O., M.D., C.F., and D.G.P. analyzed data; and L.A.O. and D.G.P. wrote the paper.
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The authors declare no conflict of interest.
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This article contains supporting information online at www.pnas.org/cgi/content/full/0704421104/DC1.
- Abbreviations:
- BAL,
- bronchoalveolar lavage;
- BLM,
- bleomycin;
- IL1RN,
- interluekin 1 receptor antagonist;
- ILD,
- interstitial lung disease;
- MSC,
- mesenchymal stem cell;
- SAGE,
- serial analysis of gene expression.
-
Freely available online through the PNAS open access option.
- © 2007 by The National Academy of Sciences of the USA
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Interleukin 1 receptor antagonist mediates the antiinflammatory and antifibrotic effect of mesenchymal stem cells during lung injury
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