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Table of Contents
September 25, 2007; vol. 104 no. 39
This Week in PNAS
Profile
Going Beyond Panaceas Special Feature (free online)
Perspectives
Research Articles
- You have accessPanaceas, uncertainty, and the robust control framework in sustainability scienceJohn M. Anderies, Armando A. Rodriguez, Marco A. Janssen, and Oguzhan Cifdaloz
- You have accessPanaceas and diversification of environmental policy
- From the Cover
William A. Brock and Stephen R. Carpenter - You have accessThe precursors of governance in the Maine lobster fisheryJames Wilson, Liying Yan, and Carl Wilson
Physical Sciences
Applied Physical Sciences
- You have accessExtracting the hierarchical organization of complex systemsMarta Sales-Pardo, Roger Guimerà, André A. Moreira, and Luís A. Nunes Amaral
- You have accessElectrostatic interactions in phospholipid membranes revealed by coherent 2D IR spectroscopyV. V. Volkov, R. Chelli, W. Zhuang, F. Nuti, Y. Takaoka, A. M. Papini, S. Mukamel, and R. Righini
Chemistry
- You have accessDehydration-driven solvent exposure of hydrophobic surfaces as a driving force in peptide foldingIsabella Daidone, Martin B. Ulmschneider, Alfredo Di Nola, Andrea Amadei, and Jeremy C. Smith
- Open AccessSynthesis of crystals with a programmable kinetic barrier to nucleationRebecca Schulman and Erik Winfree
Environmental Sciences
- Open AccessChanges in climate and land use have a larger direct impact than rising CO2 on global river runoff trendsShilong Piao, Pierre Friedlingstein, Philippe Ciais, Nathalie de Noblet-Ducoudré, David Labat, and Sönke Zaehle
- Open AccessIdentification of human-induced changes in atmospheric moisture contentB. D. Santer, C. Mears, F. J. Wentz, K. E. Taylor, P. J. Gleckler, T. M. L. Wigley, T. P. Barnett, J. S. Boyle, W. Brüggemann, N. P. Gillett, S. A. Klein, G. A. Meehl, T. Nozawa, D. W. Pierce, P. A. Stott, W. M. Washington, and M. F. Wehner
See companion article:
- In This Issue- Sep 25, 2007
Physics
- You have accessQuantum spin correlations through the superconducting-to-normal phase transition in electron-doped superconducting Pr0.88LaCe0.12CuO4-δStephen D. Wilson, Shiliang Li, Jun Zhao, Gang Mu, Hai-Hu Wen, Jeffrey W. Lynn, Paul G. Freeman, Louis-Pierre Regnault, Klaus Habicht, and Pengcheng Dai
- You have accessQuantum dynamics and entanglement of spins on a square latticeN. B. Christensen, H. M. Rønnow, D. F. McMorrow, A. Harrison, T. G. Perring, M. Enderle, R. Coldea, L. P. Regnault, and G. Aeppli
- You have accessMyosin V stepping mechanismGiovanni Cappello, Paolo Pierobon, Clémentine Symonds, Lorenzo Busoni, J. Christof, M. Gebhardt, Matthias Rief, and Jacques Prost
Social Sciences
Anthropology
- Open AccessAncient DNA, pig domestication, and the spread of the Neolithic into Europe
- From the Cover
Greger Larson, Umberto Albarella, Keith Dobney, Peter Rowley-Conwy, Jörg Schibler, Anne Tresset, Jean-Denis Vigne, Ceiridwen J. Edwards, Angela Schlumbaum, Alexandru Dinu, Adrian Bălăçsescu, Gaynor Dolman, Antonio Tagliacozzo, Ninna Manaseryan, Preston Miracle, Louise Van Wijngaarden-Bakker, Marco Masseti, Daniel G. Bradley, and Alan Cooper
Political Sciences
Sustainability Science
- You have accessPanaceas, uncertainty, and the robust control framework in sustainability scienceJohn M. Anderies, Armando A. Rodriguez, Marco A. Janssen, and Oguzhan Cifdaloz
- You have accessPanaceas and diversification of environmental policy
- From the Cover
William A. Brock and Stephen R. Carpenter - You have accessThe precursors of governance in the Maine lobster fisheryJames Wilson, Liying Yan, and Carl Wilson
Biological Sciences
Agricultural Sciences
- Open AccessImprovement of water use efficiency in rice by expression of HARDY, an Arabidopsis drought and salt tolerance geneAarati Karaba, Shital Dixit, Raffaella Greco, Asaph Aharoni, Kurniawan R. Trijatmiko, Nayelli Marsch-Martinez, Arjun Krishnan, Karaba N. Nataraja, Makarla Udayakumar, and Andy Pereira
See companion article:
- In This Issue- Sep 25, 2007
Anthropology
- Open AccessAncient DNA, pig domestication, and the spread of the Neolithic into Europe
- From the Cover
Greger Larson, Umberto Albarella, Keith Dobney, Peter Rowley-Conwy, Jörg Schibler, Anne Tresset, Jean-Denis Vigne, Ceiridwen J. Edwards, Angela Schlumbaum, Alexandru Dinu, Adrian Bălăçsescu, Gaynor Dolman, Antonio Tagliacozzo, Ninna Manaseryan, Preston Miracle, Louise Van Wijngaarden-Bakker, Marco Masseti, Daniel G. Bradley, and Alan Cooper
Applied Biological Sciences
- You have accessOrphan nuclear receptor TLX recruits histone deacetylases to repress transcription and regulate neural stem cell proliferationGuoQiang Sun, Ruth T. Yu, Ronald M. Evans, and Yanhong Shi
Biochemistry
- You have accessEmergence of a fast-reacting ribozyme that is capable of undergoing continuous evolutionSarah B. Voytek and Gerald F. Joyce
- You have accessStructural determination of wild-type lactose permeaseLan Guan, Osman Mirza, Gillian Verner, So Iwata, and H. Ronald Kaback
- You have accessPathogenic mechanism of a human mitochondrial tRNAPhe mutation associated with myoclonic epilepsy with ragged red fibers syndromeJiqiang Ling, Hervé Roy, Daoming Qin, Mary Anne T. Rubio, Juan D. Alfonzo, Kurt Fredrick, and Michael Ibba
- You have accessProtein pyrophosphorylation by inositol pyrophosphates is a posttranslational eventRashna Bhandari, Adolfo Saiardi, Yousef Ahmadibeni, Adele M. Snowman, Adam C. Resnick, Troels Z. Kristiansen, Henrik Molina, Akhilesh Pandey, J. Kent Werner Jr., Krishna R. Juluri, Yong Xu, Glenn D. Prestwich, Keykavous Parang, and Solomon H. Snyder
- You have accessCrystallographic trapping in the rebeccamycin biosynthetic enzyme RebC
- From the Cover
Katherine S. Ryan, Annaleise R. Howard-Jones, Michael J. Hamill, Sean J. Elliott, Christopher T. Walsh, and Catherine L. DrennanSee companion article:
- In This Issue- Sep 25, 2007
- Crystallography gets the jump on the enzymologists- Sep 26, 2007
- You have accessAnatomy of energetic changes accompanying urea-induced protein denaturationMatthew Auton, Luis Marcelo F. Holthauzen, and D. Wayne Bolen
Biophysics
- You have accessDehydration-driven solvent exposure of hydrophobic surfaces as a driving force in peptide foldingIsabella Daidone, Martin B. Ulmschneider, Alfredo Di Nola, Andrea Amadei, and Jeremy C. Smith
- You have accessElectrostatic interactions in phospholipid membranes revealed by coherent 2D IR spectroscopyV. V. Volkov, R. Chelli, W. Zhuang, F. Nuti, Y. Takaoka, A. M. Papini, S. Mukamel, and R. Righini
- You have accessMyosin V stepping mechanismGiovanni Cappello, Paolo Pierobon, Clémentine Symonds, Lorenzo Busoni, J. Christof, M. Gebhardt, Matthias Rief, and Jacques Prost
- You have accessStructural insight into Ca2+ specificity in tetrameric cation channelsAmer Alam, Ning Shi, and Youxing Jiang
- You have accessSimulating replica exchange simulations of protein folding with a kinetic network modelWeihua Zheng, Michael Andrec, Emilio Gallicchio, and Ronald M. Levy
- You have accessPrincipal component analysis of the pH-dependent conformational transitions of bovine β-lactoglobulin monitored by heteronuclear NMRKazumasa Sakurai and Yuji Goto
Cell Biology
- You have accessThe oxysterol binding protein Kes1p regulates Golgi apparatus phosphatidylinositol-4-phosphate functionGregory D. Fairn, Amy J. Curwin, Christopher J. Stefan, and Christopher R. McMaster
- You have accessStructural plasticity in Ig superfamily domain 4 of ICAM-1 mediates cell surface dimerizationXuehui Chen, Thomas Doohun Kim, Christopher V. Carman, Li-Zhi Mi, Gang Song, and Timothy A. Springer
- Open AccessIL-20 is an arteriogenic cytokine that remodels collateral networks and improves functions of ischemic hind limbsKaterina Tritsaris, Maja Myren, Sisse B. Ditlev, Martin V. Hübschmann, Ida van der Blom, Anker Jon Hansen, Uffe B. Olsen, Renhai Cao, Junhang Zhang, Tanghong Jia, Eric Wahlberg, Steen Dissing, and Yihai Cao
- Open AccessProcessing and function of CFTR-ΔF508 are species-dependentLynda S. Ostedgaard, Christopher S. Rogers, Qian Dong, Christoph O. Randak, Daniel W. Vermeer, Tatiana Rokhlina, Philip H. Karp, and Michael J. Welsh
Developmental Biology
- You have accessDistinct requirements for Gab1 in Met and EGF receptor signaling in vivoUte Schaeper, Regina Vogel, Jolanta Chmielowiec, Joerg Huelsken, Marta Rosario, and Walter Birchmeier
- Open AccessThe E-protein Tcf4 interacts with Math1 to regulate differentiation of a specific subset of neuronal progenitorsAdriano Flora, Jesus J. Garcia, Christina Thaller, and Huda Y. Zoghbi
Evolution
- You have accessMetabolic rate does not calibrate the molecular clockRobert Lanfear, Jessica A. Thomas, John J. Welch, Thomas Brey, and Lindell Bromham
Genetics
- You have accessA mouse model for nonsense mutation bypass therapy shows a dramatic multiday response to geneticinChunmei Yang, Jinong Feng, Wenjia Song, Jicheng Wang, Becky Tsai, Yunwu Zhang, William A. Scaringe, Kathleen A. Hill, Paris Margaritis, Katherine A. High, and Steve S. Sommer
- You have accessSpecific tumor suppressor function for E2F2 in Myc-induced T cell lymphomagenesisRene Opavsky, Shih-Yin Tsai, Martin Guimond, Anjulie Arora, Jana Opavska, Brian Becknell, Michael Kaufmann, Nathaniel A. Walton, Julie A. Stephens, Soledad A. Fernandez, Natarajan Muthusamy, Dean W. Felsher, Pierluigi Porcu, Michael A. Caligiuri, and Gustavo Leone
- You have accessGlobal transcriptional responses to cisplatin in Dictyostelium discoideum identify potential drug targetsNancy Van Driessche, Hannah Alexander, Junxia Min, Adam Kuspa, Stephen Alexander, and Gad Shaulsky
- You have accessSpecies-specific positive selection of the male-specific lethal complex that participates in dosage compensation in DrosophilaMonica A. Rodriguez, Danielle Vermaak, Joshua J. Bayes, and Harmit S. Malik
- You have accessGene expression patterns of human colon tops and basal crypts and BMP antagonists as intestinal stem cell niche factorsCynthia Kosinski, Vivian S. W. Li, Annie S. Y. Chan, Ji Zhang, Coral Ho, Wai Yin Tsui, Tsun Leung Chan, Randy C. Mifflin, Don W. Powell, Siu Tsan Yuen, Suet Yi Leung, and Xin Chen
Immunology
- You have accessWiskott–Aldrich syndrome protein (WASP) and N-WASP are critical for T cell developmentVinicius Cotta-de-Almeida, Lisa Westerberg, Michel H. Maillard, Dilek Onaldi, Heather Wachtel, Parool Meelu, Ung-il Chung, Ramnik Xavier, Frederick W. Alt, and Scott B. Snapper
- You have accessViral targeting of fibroblastic reticular cells contributes to immunosuppression and persistence during chronic infectionScott N. Mueller, Mehrdad Matloubian, Daniel M. Clemens, Arlene H. Sharpe, Gordon J. Freeman, Shivaprakash Gangappa, Christian P. Larsen, and Rafi Ahmed
- Open AccessWnt5a inhibits canonical Wnt signaling in hematopoietic stem cells and enhances repopulationMichael J. Nemeth, Lilia Topol, Stacie M. Anderson, Yingzi Yang, and David M. Bodine
- You have accessγc cytokines condition the progressive differentiation of CD4+ T cellsGuillemette X. Masse, Erwan Corcuff, Hélène Strick-Marchand, Delphine Guy-Grand, Anna Tafuri-Bladt, Matthew L. Albert, Olivier Lantz, and James P. Di Santo
- You have accessIdentification of a peripheral blood transcriptional biomarker panel associated with operational renal allograft toleranceSophie Brouard, Elaine Mansfield, Christophe Braud, Li Li, Magali Giral, Szu-chuan Hsieh, Dominique Baeten, Meixia Zhang, Joanna Ashton-Chess, Cécile Braudeau, Frank Hsieh, Alexandre Dupont, Annaik Pallier, Anne Moreau, Stéphanie Louis, Catherine Ruiz, Oscar Salvatierra, Jean-Paul Soulillou, and Minnie Sarwal
- You have accessNotch1 engagement by Delta-like-1 promotes differentiation of B lymphocytes to antibody-secreting cellsMargarida Almeida Santos, Leonor Morais Sarmento, Manuel Rebelo, Ana Agua Doce, Ivan Maillard, Alexis Dumortier, Helia Neves, Freddy Radtke, Warren S. Pear, Leonor Parreira, and Jocelyne Demengeot
- You have accessSustained antigen presentation can promote an immunogenic T cell response, like dendritic cell activationReinhard Obst, Hisse-Martien van Santen, Rachel Melamed, Alice O. Kamphorst, Christophe Benoist, and Diane Mathis
Mathematics
- You have accessShannon's monotonicity problem for free and classical entropyDimitri Shlyakhtenko and with appendix by Hanne Schultz
Medical Sciences
- You have accessPAS kinase is required for normal cellular energy balanceHuai-Xiang Hao, Caleb M. Cardon, Wojtek Swiatek, Robert C. Cooksey, Tammy L. Smith, James Wilde, Sihem Boudina, E. Dale Abel, Donald A. McClain, and Jared Rutter
- You have accessTumor-suppressive miR-34a induces senescence-like growth arrest through modulation of the E2F pathway in human colon cancer cellsHiroshi Tazawa, Naoto Tsuchiya, Masashi Izumiya, and Hitoshi Nakagama
- Open AccessNitric oxide induces CD4+CD25+ Foxp3− regulatory T cells from CD4+CD25− T cells via p53, IL-2, and OX40Wanda Niedbala, Beilei Cai, Haiying Liu, Nick Pitman, Lynda Chang, and Foo Y. Liew
- You have accessMicroRNAs regulate synthesis of the neurotransmitter substance P in human mesenchymal stem cell-derived neuronal cellsSteven J. Greco and Pranela Rameshwar
- Open AccessTargeting thyroid hormone receptor-β agonists to the liver reduces cholesterol and triglycerides and improves the therapeutic index
- From the Cover
Mark D. Erion, Edward E. Cable, Bruce R. Ito, Hongjian Jiang, James M. Fujitaki, Patricia D. Finn, Bao-Hong Zhang, Jinzhao Hou, Serge H. Boyer, Paul D. van Poelje, and David L. LinemeyerSee companion article:
- In This Issue- Sep 25, 2007
Microbiology
- You have accessRegulatory T cell-like responses in deer mice persistently infected with Sin Nombre virusTony Schountz, Joseph Prescott, Ann C. Cogswell, Lauren Oko, Katy Mirowsky-Garcia, Alejandra P. Galvez, and Brian Hjelle
- You have accessRegulatory T cells enhance persistence of the zoonotic pathogen Seoul virus in its reservoir hostJudith D. Easterbrook, M. Christine Zink, and Sabra L. Klein
See companion article:
- In This Issue- Sep 25, 2007
- You have accessType VI secretion system translocates a phage tail spike-like protein into target cells where it cross-links actinStefan Pukatzki, Amy T. Ma, Andrew T. Revel, Derek Sturtevant, and John J. Mekalanos
Neuroscience
- Open AccessDmbx1 is essential in agouti-related protein actionWakako Fujimoto, Tetsuya Shiuchi, Takashi Miki, Yasuhiko Minokoshi, Yoshihisa Takahashi, Ayako Takeuchi, Kazuhiro Kimura, Masayuki Saito, Toshihiko Iwanaga, and Susumu Seino
- You have accessRapid seasonal-like regression of the adult avian song control systemChristopher K. Thompson, George E. Bentley, and Eliot A. Brenowitz
- You have accessProperties of GluR3 receptors tagged with GFP at the amino or carboxyl terminusAgenor Limon, Jorge Mauricio Reyes-Ruiz, Fabrizio Eusebi, and Ricardo Miledi
- You have accessResting-state networks in the infant brainPeter Fransson, Beatrice Skiöld, Sandra Horsch, Anders Nordell, Mats Blennow, Hugo Lagercrantz, and Ulrika Åden
- You have accessFragile X mental retardation protein deficiency leads to excessive mGluR5-dependent internalization of AMPA receptorsMika Nakamoto, Vijayalaxmi Nalavadi, Michael P. Epstein, Usha Narayanan, Gary J. Bassell, and Stephen T. Warren
Pharmacology
- You have accessPhospholipase Cε is a nexus for Rho and Rap-mediated G protein-coupled receptor-induced astrocyte proliferationSimona Citro, Sundeep Malik, Emily A. Oestreich, Julie Radeff-Huang, Grant G. Kelley, Alan V. Smrcka, and Joan Heller Brown
- Open AccessImpact of tumor-specific targeting on the biodistribution and efficacy of siRNA nanoparticles measured by multimodality in vivo imagingDerek W. Bartlett, Helen Su, Isabel J. Hildebrandt, Wolfgang A. Weber, and Mark E. Davis
Physiology
- You have accessYeast screens show aromatic residues at the end of the sixth helix anchor transient receptor potential channel gateXinliang Zhou, Zhenwei Su, Andriy Anishkin, W. John Haynes, Eric M. Friske, Stephen H. Loukin, Ching Kung, and Yoshiro Saimi
- You have accessHydrogen sulfide attenuates myocardial ischemia-reperfusion injury by preservation of mitochondrial functionJohn W. Elrod, John W. Calvert, Joanna Morrison, Jeannette E. Doeller, David W. Kraus, Ling Tao, Xiangying Jiao, Rosario Scalia, Levente Kiss, Csaba Szabo, Hideo Kimura, Chi-Wing Chow, and David J. Lefer
Plant Biology
- You have accessGenetic evidence for three unique components in primary cell-wall cellulose synthase complexes in ArabidopsisStaffan Persson, Alexander Paredez, Andrew Carroll, Hildur Palsdottir, Monika Doblin, Patricia Poindexter, Natalie Khitrov, Manfred Auer, and Chris R. Somerville
- You have accessOrganization of cellulose synthase complexes involved in primary cell wall synthesis in Arabidopsis thalianaThierry Desprez, Michal Juraniec, Elizabeth Faris Crowell, Hélène Jouy, Zaneta Pochylova, Francois Parcy, Herman Höfte, Martine Gonneau, and Samantha Vernhettes
- You have accessEvolution of asexual reproduction in leaves of the genus KalanchoëHelena M. P. Garcês, Connie E. M. Champagne, Brad T. Townsley, Soomin Park, Rui Malhó, Maria C. Pedroso, John J. Harada, and Neelima R. Sinha
Sustainability Science
Commentary
See companion article: