Table of Contents

Biological Sciences

• Biochemistry

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    The dual mode of action of bistramide A entails severing of filamentous actin and covalent protein modification

    Syed Alipayam Rizvi, David S. Courson, Valerie A. Keller, Ronald S. Rock, and Sergey A. Kozmin

    PNAS March 18, 2008 105 (11) 4088-4092; https://doi.org/10.1073/pnas.0710727105
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    Mass spectrometry identifies and quantifies 74 unique histone H4 isoforms in differentiating human embryonic stem cells

    Doug Phanstiel, Justin Brumbaugh, W. Travis Berggren, Kevin Conard, Xuezhu Feng, Mark E. Levenstein, Graeme C. McAlister, James A. Thomson, and Joshua J. Coon

    PNAS March 18, 2008 105 (11) 4093-4098; https://doi.org/10.1073/pnas.0710515105
  • Open Access

    A disulfide-stabilized conformer of methionine synthase reveals an unexpected role for the histidine ligand of the cobalamin cofactor

    Supratim Datta, Markos Koutmos, Katherine A. Pattridge, Martha L. Ludwig, and Rowena G. Matthews

    PNAS March 18, 2008 105 (11) 4115-4120; https://doi.org/10.1073/pnas.0800329105
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    Crystal structure of the [2Fe-2S] oxidative-stress sensor SoxR bound to DNA

    Satoshi Watanabe, Akiko Kita, Kazuo Kobayashi, and Kunio Miki

    PNAS March 18, 2008 105 (11) 4121-4126; https://doi.org/10.1073/pnas.0709188105
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    Contribution of positively charged flanking residues to the insertion of transmembrane helices into the endoplasmic reticulum

    Mirjam Lerch-Bader, Carolina Lundin, Hyun Kim, IngMarie Nilsson, and Gunnar von Heijne

    PNAS March 18, 2008 105 (11) 4127-4132; https://doi.org/10.1073/pnas.0711580105
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    Confinement of caspase-12 proteolytic activity to autoprocessing

    Sophie Roy, Jeffrey R. Sharom, Caroline Houde, Thomas P. Loisel, John P. Vaillancourt, Wei Shao, Maya Saleh, and Donald W. Nicholson

    PNAS March 18, 2008 105 (11) 4133-4138; https://doi.org/10.1073/pnas.0706658105

• Biophysics

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    Comparing bird and human soaring strategies

    Zsuzsa Ákos, Máté Nagy, and Tamás Vicsek

    PNAS March 18, 2008 105 (11) 4139-4143; https://doi.org/10.1073/pnas.0707711105

    See companion article:

    • In This Issue

      - Mar 18, 2008
  • Open Access

    Structural inference of native and partially folded RNA by high-throughput contact mapping

    Rhiju Das, Madhuri Kudaravalli, Magdalena Jonikas, Alain Laederach, Robert Fong, Jason P. Schwans, David Baker, Joseph A. Piccirilli, Russ B. Altman, and Daniel Herschlag

    PNAS March 18, 2008 105 (11) 4144-4149; https://doi.org/10.1073/pnas.0709032105
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    Manipulation of the mechanical properties of a virus by protein engineering

    Carolina Carrasco, Milagros Castellanos, Pedro J. de Pablo, and Mauricio G. Mateu

    PNAS March 18, 2008 105 (11) 4150-4155; https://doi.org/10.1073/pnas.0708017105
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    Fluorescence resonance energy transfer in near-infrared fluorescent oligonucleotide probes for detecting protein–DNA interactions

    Surong Zhang, Valeri Metelev, David Tabatadze, Paul C. Zamecnik, and Alexei Bogdanov Jr

    PNAS March 18, 2008 105 (11) 4156-4161; https://doi.org/10.1073/pnas.0800162105

• Cell Biology

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    Isoform-specific monoubiquitination, endocytosis, and degradation of alternatively spliced ErbB4 isoforms

    Maria Sundvall, Anna Korhonen, Ilkka Paatero, Eugenio Gaudio, Gerry Melino, Carlo M. Croce, Rami I. Aqeilan, and Klaus Elenius

    PNAS March 18, 2008 105 (11) 4162-4167; https://doi.org/10.1073/pnas.0708333105
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    Specific requirement of the chromatin modifier mSin3B in cell cycle exit and cellular differentiation

    Gregory David, Kathryn B. Grandinetti, Patricia M. Finnerty, Natalie Simpson, Gerald C. Chu, and Ronald A. DePinho

    PNAS March 18, 2008 105 (11) 4168-4172; https://doi.org/10.1073/pnas.0710285105
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    NFAR-1 and -2 modulate translation and are required for efficient host defense

    Ingrid Pfeifer, Rachel Elsby, Marilyn Fernandez, Paula A. Faria, Daniel R. Nussenzveig, Izidor S. Lossos, Beatriz M. A. Fontoura, W. David Martin, and Glen N. Barber

    PNAS March 18, 2008 105 (11) 4173-4178; https://doi.org/10.1073/pnas.0711222105
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    Histone deacetylase 3 localizes to the mitotic spindle and is required for kinetochore–microtubule attachment

    Sumiyasu Ishii, Yasuhiro Kurasawa, Jiemin Wong, and Li-yuan Yu-Lee

    PNAS March 18, 2008 105 (11) 4179-4184; https://doi.org/10.1073/pnas.0710140105

• Developmental Biology

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    Unique SMAD1/5/8 activity at the phalanx-forming region determines digit identity

    Takayuki Suzuki, Sean M. Hasso, and John F. Fallon

    PNAS March 18, 2008 105 (11) 4185-4190; https://doi.org/10.1073/pnas.0707899105

    See companion article:

    • In This Issue

      - Mar 18, 2008

• Ecology

  • Open Access

    Size, foraging, and food web structure

    • From the Cover

    Owen L. Petchey, Andrew P. Beckerman, Jens O. Riede, and Philip H. Warren

    PNAS March 18, 2008 105 (11) 4191-4196; https://doi.org/10.1073/pnas.0710672105

    See companion article:

    • The “Goldilocks factor” in food webs

      - Mar 11, 2008
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    A rapid upward shift of a forest ecotone during 40 years of warming in the Green Mountains of Vermont

    Brian Beckage, Ben Osborne, Daniel G. Gavin, Carolyn Pucko, Thomas Siccama, and Timothy Perkins

    PNAS March 18, 2008 105 (11) 4197-4202; https://doi.org/10.1073/pnas.0708921105
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    Heat stress causes inhibition of the de novo synthesis of antenna proteins and photobleaching in cultured Symbiodinium

    Shunichi Takahashi, Spencer Whitney, Shigeru Itoh, Tadashi Maruyama, and Murray Badger

    PNAS March 18, 2008 105 (11) 4203-4208; https://doi.org/10.1073/pnas.0708554105

• Environmental Sciences

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    Rapid chemotactic response enables marine bacteria to exploit ephemeral microscale nutrient patches

    Roman Stocker, Justin R. Seymour, Azadeh Samadani, Dana E. Hunt, and Martin F. Polz

    PNAS March 18, 2008 105 (11) 4209-4214; https://doi.org/10.1073/pnas.0709765105

• Evolution

  • Open Access

    Active tails enhance arboreal acrobatics in geckos

    • From the Cover

    Ardian Jusufi, Daniel I. Goldman, Shai Revzen, and Robert J. Full

    PNAS March 18, 2008 105 (11) 4215-4219; https://doi.org/10.1073/pnas.0711944105
  • Open Access

    Possible involvement of SINEs in mammalian-specific brain formation

    Takeshi Sasaki, Hidenori Nishihara, Mika Hirakawa, Koji Fujimura, Mikiko Tanaka, Nobuhiro Kokubo, Chiharu Kimura-Yoshida, Isao Matsuo, Kenta Sumiyama, Naruya Saitou, Tomomi Shimogori, and Norihiro Okada

    PNAS March 18, 2008 105 (11) 4220-4225; https://doi.org/10.1073/pnas.0709398105
  • Open Access

    Insulin signaling is involved in the regulation of worker division of labor in honey bee colonies

    Seth A. Ament, Miguel Corona, Henry S. Pollock, and Gene E. Robinson

    PNAS March 18, 2008 105 (11) 4226-4231; https://doi.org/10.1073/pnas.0800630105

• Genetics

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    Mutations in the very low-density lipoprotein receptor VLDLR cause cerebellar hypoplasia and quadrupedal locomotion in humans

    Tayfun Ozcelik, Nurten Akarsu, Elif Uz, Safak Caglayan, Suleyman Gulsuner, Onur Emre Onat, Meliha Tan, and Uner Tan

    PNAS March 18, 2008 105 (11) 4232-4236; https://doi.org/10.1073/pnas.0710010105
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    A mitotic recombination system for mouse chromosome 17

    Lei Sun, Xiaohui Wu, Min Han, Tian Xu, and Yuan Zhuang

    PNAS March 18, 2008 105 (11) 4237-4241; https://doi.org/10.1073/pnas.0800798105
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    Bardet–Biedl syndrome proteins are required for the localization of G protein-coupled receptors to primary cilia

    Nicolas F. Berbari, Jacqueline S. Lewis, Georgia A. Bishop, Candice C. Askwith, and Kirk Mykytyn

    PNAS March 18, 2008 105 (11) 4242-4246; https://doi.org/10.1073/pnas.0711027105
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    Distinct effects of the recurrent Mlh1^G67R mutation on MMR functions, cancer, and meiosis

    Elena Avdievich, Cora Reiss, Stefan J. Scherer, Yongwei Zhang, Sandra M. Maier, Bo Jin, Harry Hou Jr, Andreas Rosenwald, Hubertus Riedmiller, Raju Kucherlapati, Paula E. Cohen, Winfried Edelmann, and Burkhard Kneitz

    PNAS March 18, 2008 105 (11) 4247-4252; https://doi.org/10.1073/pnas.0800276105
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    Genomic imprinting effects on adult body composition in mice

    James M. Cheverud, Reinmar Hager, Charles Roseman, Gloria Fawcett, Bing Wang, and Jason B. Wolf

    PNAS March 18, 2008 105 (11) 4253-4258; https://doi.org/10.1073/pnas.0706562105

• Immunology

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    Bystander B cells rapidly acquire antigen receptors from activated B cells by membrane transfer

    Ben J. C. Quah, Vaughan P. Barlow, Virginia McPhun, Klaus I. Matthaei, Mark D. Hulett, and Christopher R. Parish

    PNAS March 18, 2008 105 (11) 4259-4264; https://doi.org/10.1073/pnas.0800259105

• Medical Sciences

  • Open Access

    IgG glycan hydrolysis by a bacterial enzyme as a therapy against autoimmune conditions

    • From the Cover

    Mattias Collin, Oonagh Shannon, and Lars Björck

    PNAS March 18, 2008 105 (11) 4265-4270; https://doi.org/10.1073/pnas.0711271105

    See companion article:

    • Making autoantibodies safe

      - Mar 14, 2008
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    PPARδ regulates multiple proinflammatory pathways to suppress atherosclerosis

    Grant D. Barish, Annette R. Atkins, Michael Downes, Peter Olson, Ling-Wa Chong, Mike Nelson, Yuhua Zou, Hoosang Hwang, Heonjoong Kang, Linda Curtiss, Ronald M. Evans, and Chih-Hao Lee

    PNAS March 18, 2008 105 (11) 4271-4276; https://doi.org/10.1073/pnas.0711875105
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    PPARδ-mediated antiinflammatory mechanisms inhibit angiotensin II-accelerated atherosclerosis

    Yasunori Takata, Joey Liu, Fen Yin, Alan R. Collins, Christopher J. Lyon, Chih-Hao Lee, Annette R. Atkins, Michael Downes, Grant D. Barish, Ronald M. Evans, Willa A. Hsueh, and Rajendra K. Tangirala

    PNAS March 18, 2008 105 (11) 4277-4282; https://doi.org/10.1073/pnas.0708647105
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    Comparative lesion sequencing provides insights into tumor evolution

    Siân Jones, Wei-dong Chen, Giovanni Parmigiani, Frank Diehl, Niko Beerenwinkel, Tibor Antal, Arne Traulsen, Martin A. Nowak, Christopher Siegel, Victor E. Velculescu, Kenneth W. Kinzler, Bert Vogelstein, Joseph Willis, and Sanford D. Markowitz

    PNAS March 18, 2008 105 (11) 4283-4288; https://doi.org/10.1073/pnas.0712345105

    See companion article:

    • In This Issue

      - Mar 18, 2008
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    Intermittent recombinant TSH injections prevent ovariectomy-induced bone loss

    Li Sun, Slobodan Vukicevic, Ramkumarie Baliram, Guozhe Yang, Rebecca Sendak, John McPherson, Ling-Ling Zhu, Jameel Iqbal, Rauf Latif, Arjun Natrajan, Ario Arabi, Kosj Yamoah, Baljit S. Moonga, Yankel Gabet, Terry F. Davies, Itai Bab, Etsuko Abe, Kuber Sampath, and Mone Zaidi

    PNAS March 18, 2008 105 (11) 4289-4294; https://doi.org/10.1073/pnas.0712395105
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    Acetylcholinesterase inhibitors and Gulf War illnesses

    Beatrice Alexandra Golomb

    PNAS March 18, 2008 105 (11) 4295-4300; https://doi.org/10.1073/pnas.0711986105
  • Open Access

    Correctly folded Pfs48/45 protein of Plasmodium falciparum elicits malaria transmission-blocking immunity in mice

    Nikolay S. Outchkourov, Will Roeffen, Anita Kaan, Josephine Jansen, Adrian Luty, Danielle Schuiffel, Geert Jan van Gemert, Marga van de Vegte-Bolmer, Robert W. Sauerwein, and Hendrik G. Stunnenberg

    PNAS March 18, 2008 105 (11) 4301-4305; https://doi.org/10.1073/pnas.0800459105
  • Open Access

    Mutational load distribution analysis yields metrics reflecting genetic instability during pancreatic carcinogenesis

    Gemma Tarafa, David Tuck, Daniela Ladner, Mark Topazian, Randall Brand, Carolyn Deters, Victor Moreno, Gabriel Capella, Henry Lynch, Paul Lizardi, and Jose Costa

    PNAS March 18, 2008 105 (11) 4306-4311; https://doi.org/10.1073/pnas.0708250105
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    Anthrax lethal toxin and Salmonella elicit the common cell death pathway of caspase-1-dependent pyroptosis via distinct mechanisms

    Susan L. Fink, Tessa Bergsbaken, and Brad T. Cookson

    PNAS March 18, 2008 105 (11) 4312-4317; https://doi.org/10.1073/pnas.0707370105
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    Long-term enhancement of skeletal muscle mass and strength by single gene administration of myostatin inhibitors

    Amanda M. Haidet, Liza Rizo, Chalonda Handy, Priya Umapathi, Amy Eagle, Chris Shilling, Daniel Boue, Paul T. Martin, Zarife Sahenk, Jerry R. Mendell, and Brian K. Kaspar

    PNAS March 18, 2008 105 (11) 4318-4322; https://doi.org/10.1073/pnas.0709144105

    See companion article:

    • In This Issue

      - Mar 18, 2008
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    Network properties of genes harboring inherited disease mutations

    Igor Feldman, Andrey Rzhetsky, and Dennis Vitkup

    PNAS March 18, 2008 105 (11) 4323-4328; https://doi.org/10.1073/pnas.0701722105
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    Human embryonic stem cell microenvironment suppresses the tumorigenic phenotype of aggressive cancer cells

    Lynne-Marie Postovit, Naira V. Margaryan, Elisabeth A. Seftor, Dawn A. Kirschmann, Alina Lipavsky, William W. Wheaton, Daniel E. Abbott, Richard E. B. Seftor, and Mary J. C. Hendrix

    PNAS March 18, 2008 105 (11) 4329-4334; https://doi.org/10.1073/pnas.0800467105
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    Profound functional and signaling changes in viable inflammatory neutrophils homing to cystic fibrosis airways

    Rabindra Tirouvanziam, Yael Gernez, Carol K. Conrad, Richard B. Moss, Iris Schrijver, Colleen E. Dunn, Zoe A. Davies, Leonore A. Herzenberg, and Leonard A. Herzenberg

    PNAS March 18, 2008 105 (11) 4335-4339; https://doi.org/10.1073/pnas.0712386105
  • Open Access

    Genome-wide association study provides evidence for a breast cancer risk locus at 6q22.33

    Bert Gold, Tomas Kirchhoff, Stefan Stefanov, James Lautenberger, Agnes Viale, Judy Garber, Eitan Friedman, Steven Narod, Adam B. Olshen, Peter Gregersen, Kristi Kosarin, Adam Olsh, Julie Bergeron, Nathan A. Ellis, Robert J. Klein, Andrew G. Clark, Larry Norton, Michael Dean, Jeff Boyd, and Kenneth Offit

    PNAS March 18, 2008 105 (11) 4340-4345; https://doi.org/10.1073/pnas.0800441105

• Microbiology

  • Open Access

    Phenylalanine-427 of anthrax protective antigen functions in both pore formation and protein translocation

    Jianjun Sun, Alexander E. Lang, Klaus Aktories, and R. John Collier

    PNAS March 18, 2008 105 (11) 4346-4351; https://doi.org/10.1073/pnas.0800701105
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    p72 DEAD box RNA helicase is required for optimal function of the zinc-finger antiviral protein

    Guifang Chen, Xuemin Guo, Fengxiang Lv, Yihui Xu, and Guangxia Gao

    PNAS March 18, 2008 105 (11) 4352-4357; https://doi.org/10.1073/pnas.0712276105
  • Open Access

    Helicobacter pylori evolution during progression from chronic atrophic gastritis to gastric cancer and its impact on gastric stem cells

    Marios Giannakis, Swaine L. Chen, Sherif M. Karam, Lars Engstrand, and Jeffrey I. Gordon

    PNAS March 18, 2008 105 (11) 4358-4363; https://doi.org/10.1073/pnas.0800668105
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    Production and sequence validation of a complete full length ORF collection for the pathogenic bacterium Vibrio cholerae

    Andreas Rolfs, Wagner R. Montor, Sang Sun Yoon, Yanhui Hu, Bhupinder Bhullar, Fontina Kelley, Seamus McCarron, Daniel A. Jepson, Binghua Shen, Elena Taycher, Stephanie E. Mohr, Dongmei Zuo, Janice Williamson, John Mekalanos, and Joshua LaBaer

    PNAS March 18, 2008 105 (11) 4364-4369; https://doi.org/10.1073/pnas.0712049105
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    Advantages of a single-cycle production assay to study cell culture-adaptive mutations of hepatitis C virus

    Rodney S. Russell, Jean-Christophe Meunier, Shingo Takikawa, Kristina Faulk, Ronald E. Engle, Jens Bukh, Robert H. Purcell, and Suzanne U. Emerson

    PNAS March 18, 2008 105 (11) 4370-4375; https://doi.org/10.1073/pnas.0800422105
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    Mycobacterial persistence requires the utilization of host cholesterol

    Amit K. Pandey and Christopher M. Sassetti

    PNAS March 18, 2008 105 (11) 4376-4380; https://doi.org/10.1073/pnas.0711159105
  • Open Access

    A new influenza virus virulence determinant: The NS1 protein four C-terminal residues modulate pathogenicity

    David Jackson, Md. Jaber Hossain, Danielle Hickman, Daniel R. Perez, and Robert A. Lamb

    PNAS March 18, 2008 105 (11) 4381-4386; https://doi.org/10.1073/pnas.0800482105
  • Open Access

    A trispecies Aspergillus microarray: Comparative transcriptomics of three Aspergillus species

    Mikael R. Andersen, Wanwipa Vongsangnak, Gianni Panagiotou, Margarita P. Salazar, Linda Lehmann, and Jens Nielsen

    PNAS March 18, 2008 105 (11) 4387-4392; https://doi.org/10.1073/pnas.0709964105
  • Open Access

    Bet-hedging and epigenetic inheritance in bacterial cell development

    Jan-Willem Veening, Eric J. Stewart, Thomas W. Berngruber, François Taddei, Oscar P. Kuipers, and Leendert W. Hamoen

    PNAS March 18, 2008 105 (11) 4393-4398; https://doi.org/10.1073/pnas.0700463105

• Neuroscience

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    A human intracranial study of long-range oscillatory coherence across a frontal–occipital–hippocampal brain network during visual object processing

    Pejman Sehatpour, Sophie Molholm, Theodore H. Schwartz, Jeannette R. Mahoney, Ashesh D. Mehta, Daniel C. Javitt, Patric K. Stanton, and John J. Foxe

    PNAS March 18, 2008 105 (11) 4399-4404; https://doi.org/10.1073/pnas.0708418105
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    Increased amphetamine-induced hyperactivity and reward in mice overexpressing the dopamine transporter

    Ali Salahpour, Amy J. Ramsey, Ivan O. Medvedev, Brian Kile, Tatyana D. Sotnikova, Ericka Holmstrand, Valentina Ghisi, Peter J. Nicholls, Ling Wong, Karen Murphy, Susan R. Sesack, R. Mark Wightman, Raul R. Gainetdinov, and Marc G. Caron

    PNAS March 18, 2008 105 (11) 4405-4410; https://doi.org/10.1073/pnas.0707646105
  • Open Access

    Optical measurement of synaptic glutamate spillover and reuptake by linker optimized glutamate-sensitive fluorescent reporters

    Samuel Andrew Hires, Yongling Zhu, and Roger Y. Tsien

    PNAS March 18, 2008 105 (11) 4411-4416; https://doi.org/10.1073/pnas.0712008105
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    Temporal compression mediated by short-term synaptic plasticity

    Christian Leibold, Anja Gundlfinger, Robert Schmidt, Kay Thurley, Dietmar Schmitz, and Richard Kempter

    PNAS March 18, 2008 105 (11) 4417-4422; https://doi.org/10.1073/pnas.0708711105
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    Enduring effects of early structured noise exposure on temporal modulation in the primary auditory cortex

    Xiaoming Zhou and Michael M. Merzenich

    PNAS March 18, 2008 105 (11) 4423-4428; https://doi.org/10.1073/pnas.0800009105
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    Aberrant early-phase ERK inactivation impedes neuronal function in fragile X syndrome

    Soong Ho Kim, Julie A. Markham, Ivan Jeanne Weiler, and William T. Greenough

    PNAS March 18, 2008 105 (11) 4429-4434; https://doi.org/10.1073/pnas.0800257105
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    Molecular mechanisms that control initiation and termination of physiological depolarization-evoked transmitter release

    Yonatan M. Kupchik, Grigory Rashkovan, Lily Ohana, Tal Keren-Raifman, Nathan Dascal, Hanna Parnas, and Itzchak Parnas

    PNAS March 18, 2008 105 (11) 4435-4440; https://doi.org/10.1073/pnas.0708540105
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    Alzheimer's disease is associated with reduced expression of energy metabolism genes in posterior cingulate neurons

    Winnie S. Liang, Eric M. Reiman, Jon Valla, Travis Dunckley, Thomas G. Beach, Andrew Grover, Tracey L. Niedzielko, Lonnie E. Schneider, Diego Mastroeni, Richard Caselli, Walter Kukull, John C. Morris, Christine M. Hulette, Donald Schmechel, Joseph Rogers, and Dietrich A. Stephan

    PNAS March 18, 2008 105 (11) 4441-4446; https://doi.org/10.1073/pnas.0709259105
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    The distribution of category and location information across object-selective regions in human visual cortex

    Rebecca F. Schwarzlose, Jascha D. Swisher, Sabin Dang, and Nancy Kanwisher

    PNAS March 18, 2008 105 (11) 4447-4452; https://doi.org/10.1073/pnas.0800431105
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    Organization of the core structure of the postsynaptic density

    Xiaobing Chen, Christine Winters, Rita Azzam, Xiang Li, James A. Galbraith, Richard D. Leapman, and Thomas S. Reese

    PNAS March 18, 2008 105 (11) 4453-4458; https://doi.org/10.1073/pnas.0800897105
  • Open Access

    A brain-specific SGK1 splice isoform regulates expression of ASIC1 in neurons

    Maria F. Arteaga, Tatjana Coric, Christoph Straub, and Cecilia M. Canessa

    PNAS March 18, 2008 105 (11) 4459-4464; https://doi.org/10.1073/pnas.0800958105
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    Experience is required for the maintenance and refinement of FM sweep selectivity in the developing auditory cortex

    Khaleel A. Razak, Marlin D. Richardson, and Zoltan M. Fuzessery

    PNAS March 18, 2008 105 (11) 4465-4470; https://doi.org/10.1073/pnas.0709504105

• Pharmacology

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    A preclinical model for predicting drug response in soft-tissue sarcoma with targeted AAVP molecular imaging

    Amin Hajitou, Dina C. Lev, Jonathan A. F. Hannay, Borys Korchin, Fernanda I. Staquicini, Suren Soghomonyan, Mian M. Alauddin, Robert S. Benjamin, Raphael E. Pollock, Juri G. Gelovani, Renata Pasqualini, and Wadih Arap

    PNAS March 18, 2008 105 (11) 4471-4476; https://doi.org/10.1073/pnas.0712184105

• Physiology

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    CAPON modulates cardiac repolarization via neuronal nitric oxide synthase signaling in the heart

    Kuan-Cheng Chang, Andreas S. Barth, Tetsuo Sasano, Eddy Kizana, Yuji Kashiwakura, Yiqiang Zhang, D. Brian Foster, and Eduardo Marbán

    PNAS March 18, 2008 105 (11) 4477-4482; https://doi.org/10.1073/pnas.0709118105
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    P-Rex2 regulates Purkinje cell dendrite morphology and motor coordination

    Sarah Donald, Trevor Humby, Ian Fyfe, Anne Segonds-Pichon, Simon A. Walker, Simon R. Andrews, W. John Coadwell, Piers Emson, Lawrence S. Wilkinson, and Heidi C. E. Welch

    PNAS March 18, 2008 105 (11) 4483-4488; https://doi.org/10.1073/pnas.0712324105

• Plant Biology

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    Auxin transport inhibitors impair vesicle motility and actin cytoskeleton dynamics in diverse eukaryotes

    Pankaj Dhonukshe, Ilya Grigoriev, Rainer Fischer, Motoki Tominaga, David G. Robinson, Jiří Hašek, Tomasz Paciorek, Jan Petrášek, Daniela Seifertová, Ricardo Tejos, Lee A. Meisel, Eva Zažímalová, Theodorus W. J. Gadella Jr, York-Dieter Stierhof, Takashi Ueda, Kazuhiro Oiwa, Anna Akhmanova, Roland Brock, Anne Spang, and Jiří Friml

    PNAS March 18, 2008 105 (11) 4489-4494; https://doi.org/10.1073/pnas.0711414105
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    Integration of light and abscisic acid signaling during seed germination and early seedling development

    Hao Chen, Jingyu Zhang, Michael M. Neff, Suk-Whan Hong, Huiyong Zhang, Xing-Wang Deng, and Liming Xiong

    PNAS March 18, 2008 105 (11) 4495-4500; https://doi.org/10.1073/pnas.0710778105
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    RNAi-mediated suppression of p-coumaroyl-CoA 3′-hydroxylase in hybrid poplar impacts lignin deposition and soluble secondary metabolism

    Heather D. Coleman, Ji-Young Park, Ramesh Nair, Clint Chapple, and Shawn D. Mansfield

    PNAS March 18, 2008 105 (11) 4501-4506; https://doi.org/10.1073/pnas.0706537105

• Psychology

  • Open Access

    Repetition suppression of ventromedial prefrontal activity during judgments of self and others

    • From the Cover

    Adrianna C. Jenkins, C. Neil Macrae, and Jason P. Mitchell

    PNAS March 18, 2008 105 (11) 4507-4512; https://doi.org/10.1073/pnas.0708785105

• Sustainability Science

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    Corn-based ethanol production compromises goal of reducing nitrogen export by the Mississippi River

    Simon D. Donner and Christopher J. Kucharik

    PNAS March 18, 2008 105 (11) 4513-4518; https://doi.org/10.1073/pnas.0708300105
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    Invasive plants transform the three-dimensional structure of rain forests

    Gregory P. Asner, R. Flint Hughes, Peter M. Vitousek, David E. Knapp, Ty Kennedy-Bowdoin, Joseph Boardman, Roberta E. Martin, Michael Eastwood, and Robert O. Green

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