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Table of Contents
March 18, 2008; vol. 105 no. 11
This Week in PNAS
- You have accessIn This Issue
See companion article:
- Comparing bird and human soaring strategies- Mar 03, 2008
Letters (Online Only)
- You have accessHibernation can also cause high δ15N values in cave bears: A response to Richards et alAurora Grandal d'Anglade and Daniel Fernández Mosquera
See companion article:
- You have accessReply to Grandal and Fernández: Hibernation can also cause high δ15N values in cave bearsErik Trinkaus and Michael P. Richards
See companion article:
Physical Sciences
Applied Physical Sciences
- You have accessA simple and exact Laplacian clustering of complex networking phenomena: Application to gene expression profilesChoongrak Kim, Mookyung Cheon, Minho Kang, and Iksoo Chang
Chemistry
- You have accessThe dual mode of action of bistramide A entails severing of filamentous actin and covalent protein modificationSyed Alipayam Rizvi, David S. Courson, Valerie A. Keller, Ronald S. Rock, and Sergey A. Kozmin
- You have accessMass spectrometry identifies and quantifies 74 unique histone H4 isoforms in differentiating human embryonic stem cellsDoug Phanstiel, Justin Brumbaugh, W. Travis Berggren, Kevin Conard, Xuezhu Feng, Mark E. Levenstein, Graeme C. McAlister, James A. Thomson, and Joshua J. Coon
- You have accessControlling the rates of biochemical reactions and signaling networks by shape and volume changesL. Lizana, B. Bauer, and O. Orwar
- Open AccessA disulfide-stabilized conformer of methionine synthase reveals an unexpected role for the histidine ligand of the cobalamin cofactorSupratim Datta, Markos Koutmos, Katherine A. Pattridge, Martha L. Ludwig, and Rowena G. Matthews
Social Sciences
Anthropology
- Open AccessThe protracted Holocene extinction of California's flightless sea duck (Chendytes lawi) and its implications for the Pleistocene overkill hypothesis
- From the Cover
T. L. Jones, J. F. Porcasi, J. M. Erlandson, H. Dallas Jr., T. A. Wake, and R. SchwadererSee companion article:
- Holocene underkill- Mar 11, 2008
Psychology
- You have accessA human intracranial study of long-range oscillatory coherence across a frontal–occipital–hippocampal brain network during visual object processingPejman Sehatpour, Sophie Molholm, Theodore H. Schwartz, Jeannette R. Mahoney, Ashesh D. Mehta, Daniel C. Javitt, Patric K. Stanton, and John J. Foxe
- Open AccessRepetition suppression of ventromedial prefrontal activity during judgments of self and others
- From the Cover
Adrianna C. Jenkins, C. Neil Macrae, and Jason P. Mitchell
Social Sciences
- You have accessUnderstanding the social context of the Schelling segregation modelWilliam A. V. Clark and Mark Fossett
Biological Sciences
Biochemistry
- You have accessThe dual mode of action of bistramide A entails severing of filamentous actin and covalent protein modificationSyed Alipayam Rizvi, David S. Courson, Valerie A. Keller, Ronald S. Rock, and Sergey A. Kozmin
- You have accessMass spectrometry identifies and quantifies 74 unique histone H4 isoforms in differentiating human embryonic stem cellsDoug Phanstiel, Justin Brumbaugh, W. Travis Berggren, Kevin Conard, Xuezhu Feng, Mark E. Levenstein, Graeme C. McAlister, James A. Thomson, and Joshua J. Coon
- Open AccessA disulfide-stabilized conformer of methionine synthase reveals an unexpected role for the histidine ligand of the cobalamin cofactorSupratim Datta, Markos Koutmos, Katherine A. Pattridge, Martha L. Ludwig, and Rowena G. Matthews
- You have accessCrystal structure of the [2Fe-2S] oxidative-stress sensor SoxR bound to DNASatoshi Watanabe, Akiko Kita, Kazuo Kobayashi, and Kunio Miki
- You have accessContribution of positively charged flanking residues to the insertion of transmembrane helices into the endoplasmic reticulumMirjam Lerch-Bader, Carolina Lundin, Hyun Kim, IngMarie Nilsson, and Gunnar von Heijne
- You have accessConfinement of caspase-12 proteolytic activity to autoprocessingSophie Roy, Jeffrey R. Sharom, Caroline Houde, Thomas P. Loisel, John P. Vaillancourt, Wei Shao, Maya Saleh, and Donald W. Nicholson
Biophysics
- You have accessComparing bird and human soaring strategiesZsuzsa Ákos, Máté Nagy, and Tamás Vicsek
See companion article:
- In This Issue- Mar 18, 2008
- Open AccessStructural inference of native and partially folded RNA by high-throughput contact mappingRhiju Das, Madhuri Kudaravalli, Magdalena Jonikas, Alain Laederach, Robert Fong, Jason P. Schwans, David Baker, Joseph A. Piccirilli, Russ B. Altman, and Daniel Herschlag
- You have accessManipulation of the mechanical properties of a virus by protein engineeringCarolina Carrasco, Milagros Castellanos, Pedro J. de Pablo, and Mauricio G. Mateu
- You have accessFluorescence resonance energy transfer in near-infrared fluorescent oligonucleotide probes for detecting protein–DNA interactionsSurong Zhang, Valeri Metelev, David Tabatadze, Paul C. Zamecnik, and Alexei Bogdanov Jr
Cell Biology
- You have accessIsoform-specific monoubiquitination, endocytosis, and degradation of alternatively spliced ErbB4 isoformsMaria Sundvall, Anna Korhonen, Ilkka Paatero, Eugenio Gaudio, Gerry Melino, Carlo M. Croce, Rami I. Aqeilan, and Klaus Elenius
- You have accessSpecific requirement of the chromatin modifier mSin3B in cell cycle exit and cellular differentiationGregory David, Kathryn B. Grandinetti, Patricia M. Finnerty, Natalie Simpson, Gerald C. Chu, and Ronald A. DePinho
- You have accessNFAR-1 and -2 modulate translation and are required for efficient host defenseIngrid Pfeifer, Rachel Elsby, Marilyn Fernandez, Paula A. Faria, Daniel R. Nussenzveig, Izidor S. Lossos, Beatriz M. A. Fontoura, W. David Martin, and Glen N. Barber
- You have accessHistone deacetylase 3 localizes to the mitotic spindle and is required for kinetochore–microtubule attachmentSumiyasu Ishii, Yasuhiro Kurasawa, Jiemin Wong, and Li-yuan Yu-Lee
Developmental Biology
- You have accessUnique SMAD1/5/8 activity at the phalanx-forming region determines digit identityTakayuki Suzuki, Sean M. Hasso, and John F. Fallon
See companion article:
- In This Issue- Mar 18, 2008
Ecology
- Open AccessSize, foraging, and food web structure
- From the Cover
Owen L. Petchey, Andrew P. Beckerman, Jens O. Riede, and Philip H. WarrenSee companion article:
- The “Goldilocks factor” in food webs- Mar 11, 2008
- You have accessA rapid upward shift of a forest ecotone during 40 years of warming in the Green Mountains of VermontBrian Beckage, Ben Osborne, Daniel G. Gavin, Carolyn Pucko, Thomas Siccama, and Timothy Perkins
- You have accessHeat stress causes inhibition of the de novo synthesis of antenna proteins and photobleaching in cultured SymbiodiniumShunichi Takahashi, Spencer Whitney, Shigeru Itoh, Tadashi Maruyama, and Murray Badger
Environmental Sciences
- You have accessRapid chemotactic response enables marine bacteria to exploit ephemeral microscale nutrient patchesRoman Stocker, Justin R. Seymour, Azadeh Samadani, Dana E. Hunt, and Martin F. Polz
Evolution
- Open AccessActive tails enhance arboreal acrobatics in geckos
- From the Cover
Ardian Jusufi, Daniel I. Goldman, Shai Revzen, and Robert J. Full - Open AccessPossible involvement of SINEs in mammalian-specific brain formationTakeshi Sasaki, Hidenori Nishihara, Mika Hirakawa, Koji Fujimura, Mikiko Tanaka, Nobuhiro Kokubo, Chiharu Kimura-Yoshida, Isao Matsuo, Kenta Sumiyama, Naruya Saitou, Tomomi Shimogori, and Norihiro Okada
- Open AccessInsulin signaling is involved in the regulation of worker division of labor in honey bee coloniesSeth A. Ament, Miguel Corona, Henry S. Pollock, and Gene E. Robinson
Genetics
- You have accessMutations in the very low-density lipoprotein receptor VLDLR cause cerebellar hypoplasia and quadrupedal locomotion in humansTayfun Ozcelik, Nurten Akarsu, Elif Uz, Safak Caglayan, Suleyman Gulsuner, Onur Emre Onat, Meliha Tan, and Uner Tan
- You have accessA mitotic recombination system for mouse chromosome 17Lei Sun, Xiaohui Wu, Min Han, Tian Xu, and Yuan Zhuang
- You have accessBardet–Biedl syndrome proteins are required for the localization of G protein-coupled receptors to primary ciliaNicolas F. Berbari, Jacqueline S. Lewis, Georgia A. Bishop, Candice C. Askwith, and Kirk Mykytyn
- You have accessDistinct effects of the recurrent Mlh1G67R mutation on MMR functions, cancer, and meiosisElena Avdievich, Cora Reiss, Stefan J. Scherer, Yongwei Zhang, Sandra M. Maier, Bo Jin, Harry Hou Jr, Andreas Rosenwald, Hubertus Riedmiller, Raju Kucherlapati, Paula E. Cohen, Winfried Edelmann, and Burkhard Kneitz
- You have accessGenomic imprinting effects on adult body composition in miceJames M. Cheverud, Reinmar Hager, Charles Roseman, Gloria Fawcett, Bing Wang, and Jason B. Wolf
Immunology
- You have accessBystander B cells rapidly acquire antigen receptors from activated B cells by membrane transferBen J. C. Quah, Vaughan P. Barlow, Virginia McPhun, Klaus I. Matthaei, Mark D. Hulett, and Christopher R. Parish
Medical Sciences
- Open AccessIgG glycan hydrolysis by a bacterial enzyme as a therapy against autoimmune conditions
- From the Cover
Mattias Collin, Oonagh Shannon, and Lars BjörckSee companion article:
- Making autoantibodies safe- Mar 14, 2008
- You have accessPPARδ regulates multiple proinflammatory pathways to suppress atherosclerosisGrant D. Barish, Annette R. Atkins, Michael Downes, Peter Olson, Ling-Wa Chong, Mike Nelson, Yuhua Zou, Hoosang Hwang, Heonjoong Kang, Linda Curtiss, Ronald M. Evans, and Chih-Hao Lee
- You have accessPPARδ-mediated antiinflammatory mechanisms inhibit angiotensin II-accelerated atherosclerosisYasunori Takata, Joey Liu, Fen Yin, Alan R. Collins, Christopher J. Lyon, Chih-Hao Lee, Annette R. Atkins, Michael Downes, Grant D. Barish, Ronald M. Evans, Willa A. Hsueh, and Rajendra K. Tangirala
- You have accessComparative lesion sequencing provides insights into tumor evolutionSiân Jones, Wei-dong Chen, Giovanni Parmigiani, Frank Diehl, Niko Beerenwinkel, Tibor Antal, Arne Traulsen, Martin A. Nowak, Christopher Siegel, Victor E. Velculescu, Kenneth W. Kinzler, Bert Vogelstein, Joseph Willis, and Sanford D. Markowitz
See companion article:
- In This Issue- Mar 18, 2008
- You have accessIntermittent recombinant TSH injections prevent ovariectomy-induced bone lossLi Sun, Slobodan Vukicevic, Ramkumarie Baliram, Guozhe Yang, Rebecca Sendak, John McPherson, Ling-Ling Zhu, Jameel Iqbal, Rauf Latif, Arjun Natrajan, Ario Arabi, Kosj Yamoah, Baljit S. Moonga, Yankel Gabet, Terry F. Davies, Itai Bab, Etsuko Abe, Kuber Sampath, and Mone Zaidi
- Open AccessCorrectly folded Pfs48/45 protein of Plasmodium falciparum elicits malaria transmission-blocking immunity in miceNikolay S. Outchkourov, Will Roeffen, Anita Kaan, Josephine Jansen, Adrian Luty, Danielle Schuiffel, Geert Jan van Gemert, Marga van de Vegte-Bolmer, Robert W. Sauerwein, and Hendrik G. Stunnenberg
- Open AccessMutational load distribution analysis yields metrics reflecting genetic instability during pancreatic carcinogenesisGemma Tarafa, David Tuck, Daniela Ladner, Mark Topazian, Randall Brand, Carolyn Deters, Victor Moreno, Gabriel Capella, Henry Lynch, Paul Lizardi, and Jose Costa
- You have accessAnthrax lethal toxin and Salmonella elicit the common cell death pathway of caspase-1-dependent pyroptosis via distinct mechanismsSusan L. Fink, Tessa Bergsbaken, and Brad T. Cookson
- You have accessLong-term enhancement of skeletal muscle mass and strength by single gene administration of myostatin inhibitorsAmanda M. Haidet, Liza Rizo, Chalonda Handy, Priya Umapathi, Amy Eagle, Chris Shilling, Daniel Boue, Paul T. Martin, Zarife Sahenk, Jerry R. Mendell, and Brian K. Kaspar
See companion article:
- In This Issue- Mar 18, 2008
- You have accessNetwork properties of genes harboring inherited disease mutationsIgor Feldman, Andrey Rzhetsky, and Dennis Vitkup
- You have accessHuman embryonic stem cell microenvironment suppresses the tumorigenic phenotype of aggressive cancer cellsLynne-Marie Postovit, Naira V. Margaryan, Elisabeth A. Seftor, Dawn A. Kirschmann, Alina Lipavsky, William W. Wheaton, Daniel E. Abbott, Richard E. B. Seftor, and Mary J. C. Hendrix
- You have accessProfound functional and signaling changes in viable inflammatory neutrophils homing to cystic fibrosis airwaysRabindra Tirouvanziam, Yael Gernez, Carol K. Conrad, Richard B. Moss, Iris Schrijver, Colleen E. Dunn, Zoe A. Davies, Leonore A. Herzenberg, and Leonard A. Herzenberg
- Open AccessGenome-wide association study provides evidence for a breast cancer risk locus at 6q22.33Bert Gold, Tomas Kirchhoff, Stefan Stefanov, James Lautenberger, Agnes Viale, Judy Garber, Eitan Friedman, Steven Narod, Adam B. Olshen, Peter Gregersen, Kristi Kosarin, Adam Olsh, Julie Bergeron, Nathan A. Ellis, Robert J. Klein, Andrew G. Clark, Larry Norton, Michael Dean, Jeff Boyd, and Kenneth Offit
Microbiology
- Open AccessPhenylalanine-427 of anthrax protective antigen functions in both pore formation and protein translocationJianjun Sun, Alexander E. Lang, Klaus Aktories, and R. John Collier
- You have accessp72 DEAD box RNA helicase is required for optimal function of the zinc-finger antiviral proteinGuifang Chen, Xuemin Guo, Fengxiang Lv, Yihui Xu, and Guangxia Gao
- Open AccessHelicobacter pylori evolution during progression from chronic atrophic gastritis to gastric cancer and its impact on gastric stem cellsMarios Giannakis, Swaine L. Chen, Sherif M. Karam, Lars Engstrand, and Jeffrey I. Gordon
- You have accessProduction and sequence validation of a complete full length ORF collection for the pathogenic bacterium Vibrio choleraeAndreas Rolfs, Wagner R. Montor, Sang Sun Yoon, Yanhui Hu, Bhupinder Bhullar, Fontina Kelley, Seamus McCarron, Daniel A. Jepson, Binghua Shen, Elena Taycher, Stephanie E. Mohr, Dongmei Zuo, Janice Williamson, John Mekalanos, and Joshua LaBaer
- You have accessAdvantages of a single-cycle production assay to study cell culture-adaptive mutations of hepatitis C virusRodney S. Russell, Jean-Christophe Meunier, Shingo Takikawa, Kristina Faulk, Ronald E. Engle, Jens Bukh, Robert H. Purcell, and Suzanne U. Emerson
- You have accessMycobacterial persistence requires the utilization of host cholesterolAmit K. Pandey and Christopher M. Sassetti
- Open AccessA new influenza virus virulence determinant: The NS1 protein four C-terminal residues modulate pathogenicityDavid Jackson, Md. Jaber Hossain, Danielle Hickman, Daniel R. Perez, and Robert A. Lamb
- Open AccessA trispecies Aspergillus microarray: Comparative transcriptomics of three Aspergillus speciesMikael R. Andersen, Wanwipa Vongsangnak, Gianni Panagiotou, Margarita P. Salazar, Linda Lehmann, and Jens Nielsen
- Open AccessBet-hedging and epigenetic inheritance in bacterial cell developmentJan-Willem Veening, Eric J. Stewart, Thomas W. Berngruber, François Taddei, Oscar P. Kuipers, and Leendert W. Hamoen
Neuroscience
- You have accessA human intracranial study of long-range oscillatory coherence across a frontal–occipital–hippocampal brain network during visual object processingPejman Sehatpour, Sophie Molholm, Theodore H. Schwartz, Jeannette R. Mahoney, Ashesh D. Mehta, Daniel C. Javitt, Patric K. Stanton, and John J. Foxe
- You have accessIncreased amphetamine-induced hyperactivity and reward in mice overexpressing the dopamine transporterAli Salahpour, Amy J. Ramsey, Ivan O. Medvedev, Brian Kile, Tatyana D. Sotnikova, Ericka Holmstrand, Valentina Ghisi, Peter J. Nicholls, Ling Wong, Karen Murphy, Susan R. Sesack, R. Mark Wightman, Raul R. Gainetdinov, and Marc G. Caron
- Open AccessOptical measurement of synaptic glutamate spillover and reuptake by linker optimized glutamate-sensitive fluorescent reportersSamuel Andrew Hires, Yongling Zhu, and Roger Y. Tsien
- You have accessTemporal compression mediated by short-term synaptic plasticityChristian Leibold, Anja Gundlfinger, Robert Schmidt, Kay Thurley, Dietmar Schmitz, and Richard Kempter
- You have accessEnduring effects of early structured noise exposure on temporal modulation in the primary auditory cortexXiaoming Zhou and Michael M. Merzenich
- You have accessAberrant early-phase ERK inactivation impedes neuronal function in fragile X syndromeSoong Ho Kim, Julie A. Markham, Ivan Jeanne Weiler, and William T. Greenough
- You have accessMolecular mechanisms that control initiation and termination of physiological depolarization-evoked transmitter releaseYonatan M. Kupchik, Grigory Rashkovan, Lily Ohana, Tal Keren-Raifman, Nathan Dascal, Hanna Parnas, and Itzchak Parnas
- You have accessAlzheimer's disease is associated with reduced expression of energy metabolism genes in posterior cingulate neuronsWinnie S. Liang, Eric M. Reiman, Jon Valla, Travis Dunckley, Thomas G. Beach, Andrew Grover, Tracey L. Niedzielko, Lonnie E. Schneider, Diego Mastroeni, Richard Caselli, Walter Kukull, John C. Morris, Christine M. Hulette, Donald Schmechel, Joseph Rogers, and Dietrich A. Stephan
- You have accessThe distribution of category and location information across object-selective regions in human visual cortexRebecca F. Schwarzlose, Jascha D. Swisher, Sabin Dang, and Nancy Kanwisher
- You have accessOrganization of the core structure of the postsynaptic densityXiaobing Chen, Christine Winters, Rita Azzam, Xiang Li, James A. Galbraith, Richard D. Leapman, and Thomas S. Reese
- Open AccessA brain-specific SGK1 splice isoform regulates expression of ASIC1 in neuronsMaria F. Arteaga, Tatjana Coric, Christoph Straub, and Cecilia M. Canessa
- You have accessExperience is required for the maintenance and refinement of FM sweep selectivity in the developing auditory cortexKhaleel A. Razak, Marlin D. Richardson, and Zoltan M. Fuzessery
Pharmacology
- You have accessA preclinical model for predicting drug response in soft-tissue sarcoma with targeted AAVP molecular imagingAmin Hajitou, Dina C. Lev, Jonathan A. F. Hannay, Borys Korchin, Fernanda I. Staquicini, Suren Soghomonyan, Mian M. Alauddin, Robert S. Benjamin, Raphael E. Pollock, Juri G. Gelovani, Renata Pasqualini, and Wadih Arap
Physiology
- You have accessCAPON modulates cardiac repolarization via neuronal nitric oxide synthase signaling in the heartKuan-Cheng Chang, Andreas S. Barth, Tetsuo Sasano, Eddy Kizana, Yuji Kashiwakura, Yiqiang Zhang, D. Brian Foster, and Eduardo Marbán
- You have accessP-Rex2 regulates Purkinje cell dendrite morphology and motor coordinationSarah Donald, Trevor Humby, Ian Fyfe, Anne Segonds-Pichon, Simon A. Walker, Simon R. Andrews, W. John Coadwell, Piers Emson, Lawrence S. Wilkinson, and Heidi C. E. Welch
Plant Biology
- You have accessAuxin transport inhibitors impair vesicle motility and actin cytoskeleton dynamics in diverse eukaryotesPankaj Dhonukshe, Ilya Grigoriev, Rainer Fischer, Motoki Tominaga, David G. Robinson, Jiří Hašek, Tomasz Paciorek, Jan Petrášek, Daniela Seifertová, Ricardo Tejos, Lee A. Meisel, Eva Zažímalová, Theodorus W. J. Gadella Jr, York-Dieter Stierhof, Takashi Ueda, Kazuhiro Oiwa, Anna Akhmanova, Roland Brock, Anne Spang, and Jiří Friml
- You have accessIntegration of light and abscisic acid signaling during seed germination and early seedling developmentHao Chen, Jingyu Zhang, Michael M. Neff, Suk-Whan Hong, Huiyong Zhang, Xing-Wang Deng, and Liming Xiong
- You have accessRNAi-mediated suppression of p-coumaroyl-CoA 3′-hydroxylase in hybrid poplar impacts lignin deposition and soluble secondary metabolismHeather D. Coleman, Ji-Young Park, Ramesh Nair, Clint Chapple, and Shawn D. Mansfield
Psychology
- Open AccessRepetition suppression of ventromedial prefrontal activity during judgments of self and others
- From the Cover
Adrianna C. Jenkins, C. Neil Macrae, and Jason P. Mitchell
Sustainability Science
- You have accessCorn-based ethanol production compromises goal of reducing nitrogen export by the Mississippi RiverSimon D. Donner and Christopher J. Kucharik
- You have accessInvasive plants transform the three-dimensional structure of rain forestsGregory P. Asner, R. Flint Hughes, Peter M. Vitousek, David E. Knapp, Ty Kennedy-Bowdoin, Joseph Boardman, Roberta E. Martin, Michael Eastwood, and Robert O. Green
- You have accessPlants can use protein as a nitrogen source without assistance from other organismsChanyarat Paungfoo-Lonhienne, Thierry G. A. Lonhienne, Doris Rentsch, Nicole Robinson, Michael Christie, Richard I. Webb, Harshi K. Gamage, Bernard J. Carroll, Peer M. Schenk, and Susanne Schmidt
Commentaries
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