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Table of Contents
July 22, 2008; vol. 105 no. 29
This Week in PNAS
- You have accessIn This Issue
See companion article:
- Hidden copy number variation in the HapMap population- Jul 15, 2008
Perspective
Physical Sciences
Applied Mathematics
- You have accessConservation and topology of protein interaction networks under duplication-divergence evolutionKirill Evlampiev and Hervé Isambert
- You have accessThe finite harmonic oscillator and its associated sequencesShamgar Gurevich, Ronny Hadani, and Nir Sochen
- You have accessExact subgrid interface correction schemes for elliptic interface problemsJae-Seok Huh and James A. Sethian
Applied Physical Sciences
- You have accessThe implications of human metabolic network topology for disease comorbidity
- Cozzarelli Prize Winner
- From the Cover
D.-S. Lee, J. Park, K. A. Kay, N. A. Christakis, Z. N. Oltvai, and A.-L. BarabásiSee companion article:
- Networking metabolites and diseases- Jul 16, 2008
Chemistry
- Open AccessThe role of nanostructure in the wetting behavior of mixed-monolayer-protected metal nanoparticlesA. Centrone, E. Penzo, M. Sharma, J. W. Myerson, A. M. Jackson, N. Marzari, and F. Stellacci
- You have accessInteraction of nitric oxide with a functional model of cytochrome c oxidaseJames P. Collman, Abhishek Dey, Richard A. Decreau, Ying Yang, Ali Hosseini, Edward I. Solomon, and Todd A. Eberspacher
Geology
- You have accessSterols in a unicellular relative of the metazoansRobin B. Kodner, Roger E. Summons, Ann Pearson, Nicole King, and Andrew H. Knoll
- You have accessKinetics of amorphous silica dissolution and the paradox of the silica polymorphsPatricia M. Dove, Nizhou Han, Adam F. Wallace, and James J. De Yoreo
Mathematics
Physics
Sustainability Science
- Open AccessCarbon dioxide sequestration in deep-sea basaltDavid S. Goldberg, Taro Takahashi, and Angela L. Slagle
Social Sciences
Psychology
- Open AccessConceptual knowledge increases infants' memory capacity
- From the Cover
Lisa Feigenson and Justin Halberda
Biological Sciences
Agricultural Sciences
- You have accessTransporters of arsenite in rice and their role in arsenic accumulation in rice grainJian Feng Ma, Naoki Yamaji, Namiki Mitani, Xiao-Yan Xu, Yu-Hong Su, Steve P. McGrath, and Fang-Jie Zhao
See companion article:
- In This Issue- Jul 22, 2008
Biochemistry
- You have accessReplication stalling at unstable inverted repeats: Interplay between DNA hairpins and fork stabilizing proteinsIrina Voineagu, Vidhya Narayanan, Kirill S. Lobachev, and Sergei M. Mirkin
- You have accessA βα-barrel built by the combination of fragments from different foldsTanmay A. M. Bharat, Simone Eisenbeis, Kornelius Zeth, and Birte Höcker
- You have accessFlavin-dependent thymidylate synthase X limits chromosomal DNA replicationFrédéric Escartin, Stéphane Skouloubris, Ursula Liebl, and Hannu Myllykallio
- Open AccessHost cell recognition by the henipaviruses: Crystal structures of the Nipah G attachment glycoprotein and its complex with ephrin-B3Kai Xu, Kanagalaghatta R. Rajashankar, Yee-Peng Chan, Juha P. Himanen, Christopher C. Broder, and Dimitar B. Nikolov
- You have accessA modified cysteinyl-labeling assay reveals reversible oxidation of protein tyrosine phosphatases in angiomyolipoma cellsBenoit Boivin, Sheng Zhang, Jack L. Arbiser, Zhong-Yin Zhang, and Nicholas K. Tonks
- You have accessA protein from the salivary glands of the pea aphid, Acyrthosiphon pisum, is essential in feeding on a host plantNavdeep S. Mutti, Joe Louis, Loretta K. Pappan, Kirk Pappan, Khurshida Begum, Ming-Shun Chen, Yoonseong Park, Neal Dittmer, Jeremy Marshall, John C. Reese, and Gerald R. Reeck
- You have accessThe RNA-binding proteins HYL1 and SE promote accurate in vitro processing of pri-miRNA by DCL1
- From the Cover
Zhicheng Dong, Meng-Hsuan Han, and Nina FedoroffSee companion article:
- Reconstituting plant miRNA biogenesis- Jul 16, 2008
- You have accessStructures of synthetic O-antigen fragments from serotype 2a Shigella flexneri in complex with a protective monoclonal antibodyB. Vulliez-Le Normand, F. A. Saul, A. Phalipon, F. Bélot, C. Guerreiro, L. A. Mulard, and G. A. Bentley
Biophysics
- You have accessShifting transition states in the unfolding of a large ankyrin repeat protein
- From the Cover
Nicolas D. Werbeck, Pamela J. E. Rowling, Vasuki R. Chellamuthu, and Laura S. ItzhakiSee companion article:
- You have accessDistinct conformational changes in β-arrestin report biased agonism at seven-transmembrane receptorsArun K. Shukla, Jonathan D. Violin, Erin J. Whalen, Diane Gesty-Palmer, Sudha K. Shenoy, and Robert J. Lefkowitz
- You have accessA synthetic mammalian gene circuit reveals antituberculosis compoundsWilfried Weber, Ronald Schoenmakers, Bettina Keller, Marc Gitzinger, Thomas Grau, Marie Daoud-El Baba, Peter Sander, and Martin Fussenegger
- You have accessTheoretical and experimental demonstration of the importance of specific nonnative interactions in protein foldingArash Zarrine-Afsar, Stefan Wallin, A. Mirela Neculai, Philipp Neudecker, P. Lynne Howell, Alan R. Davidson, and Hue Sun Chan
Cell Biology
- You have accessPlasma membranes are poised for activation of raft phase coalescence at physiological temperatureDaniel Lingwood, Jonas Ries, Petra Schwille, and Kai Simons
- You have accessThe role of microtubule movement in bidirectional organelle transportIgor M. Kulić, André E. X. Brown, Hwajin Kim, Comert Kural, Benjamin Blehm, Paul R. Selvin, Philip C. Nelson, and Vladimir I. Gelfand
Developmental Biology
- Open AccessCirculating blood cells function as a surveillance system for damaged tissue in Drosophila larvaeDaniel T. Babcock, Amanda R. Brock, Greg S. Fish, Yan Wang, Laurent Perrin, Mark A. Krasnow, and Michael J. Galko
Ecology
- You have accessLife-history change in disease-ravaged Tasmanian devil populationsMenna E. Jones, Andrew Cockburn, Rodrigo Hamede, Clare Hawkins, Heather Hesterman, Shelly Lachish, Diana Mann, Hamish McCallum, and David Pemberton
- You have accessLong-term resistance to simulated climate change in an infertile grasslandJ. Philip Grime, Jason D. Fridley, Andrew P. Askew, Ken Thompson, John G. Hodgson, and Chris R. Bennett
- You have accessMale-derived butterfly anti-aphrodisiac mediates induced indirect plant defense
- From the Cover
Nina E. Fatouros, Colette Broekgaarden, Gabriella Bukovinszkine'Kiss, Joop J. A. van Loon, Roland Mumm, Martinus E. Huigens, Marcel Dicke, and Monika Hilker
Evolution
- You have accessConservation and topology of protein interaction networks under duplication-divergence evolutionKirill Evlampiev and Hervé Isambert
- You have accessSterols in a unicellular relative of the metazoansRobin B. Kodner, Roger E. Summons, Ann Pearson, Nicole King, and Andrew H. Knoll
- Open AccessModular networks and cumulative impact of lateral transfer in prokaryote genome evolutionTal Dagan, Yael Artzy-Randrup, and William Martin
- You have accessEvolution of an RNP assembly system: A minimal SMN complex facilitates formation of UsnRNPs in Drosophila melanogasterMatthias Kroiss, Jörg Schultz, Julia Wiesner, Ashwin Chari, Albert Sickmann, and Utz Fischer
- You have accessFine-scale mapping of recombination rate in Drosophila refines its correlation to diversity and divergenceRob J. Kulathinal, Sarah M. Bennett, Courtney L. Fitzpatrick, and Mohamed A. F. Noor
- You have accessPhylogenetic escalation and decline of plant defense strategiesAnurag A. Agrawal and Mark Fishbein
- Open AccessThe ancestral symbiont sensor kinase CSK links photosynthesis with gene expression in chloroplastsSujith Puthiyaveetil, T. Anthony Kavanagh, Peter Cain, James A. Sullivan, Christine A. Newell, John C. Gray, Colin Robinson, Mark van der Giezen, Matthew B. Rogers, and John F. Allen
Genetics
- You have accessHidden copy number variation in the HapMap populationJohn C. Marioni, Michael White, Simon Tavaré, and Andrew G. Lynch
See companion article:
- In This Issue- Jul 22, 2008
- You have accessThe FHA domain proteins DAWDLE in Arabidopsis and SNIP1 in humans act in small RNA biogenesisBin Yu, Liu Bi, Binglian Zheng, Lijuan Ji, David Chevalier, Manu Agarwal, Vanitharani Ramachandran, Wanxiang Li, Thierry Lagrange, John C. Walker, and Xuemei Chen
- You have accessuORFs with unusual translational start codons autoregulate expression of eukaryotic ornithine decarboxylase homologsIvaylo P. Ivanov, Gary Loughran, and John F. Atkins
- You have accessThe maternal-effect, selfish genetic element Medea is associated with a composite Tc1 transposonMarcé D. Lorenzen, Andreas Gnirke, Jonathan Margolis, Jeffrey Garnes, Margie Campbell, Jeffrey J. Stuart, Rajat Aggarwal, Stephen Richards, Yoonseong Park, and Richard W. Beeman
Immunology
- Open AccessConserved T cell receptor α-chain induces insulin autoantibodiesMasakazu Kobayashi, Jean Jasinski, Edwin Liu, Marcella Li, Dongmei Miao, Li Zhang, Liping Yu, Maki Nakayama, and George S. Eisenbarth
- Open AccessStructure of UL18, a peptide-binding viral MHC mimic, bound to a host inhibitory receptorZhiru Yang and Pamela J. Bjorkman
- You have accessCXCR4–CCR5: A couple modulating T cell functionsRita Lucia Contento, Barbara Molon, Cedric Boularan, Tullio Pozzan, Santos Manes, Stefano Marullo, and Antonella Viola
- You have accessGenomic expression profiling of TNF-α-treated BDC2.5 diabetogenic CD4+ T cellsLi-Fen Lee, Chih-Jian Lih, Chao-Jen Huang, Thai Cao, Stanley N. Cohen, and Hugh O. McDevitt
- You have accessFoxp3+ natural regulatory T cells preferentially form aggregates on dendritic cells in vitro and actively inhibit their maturationYasushi Onishi, Zoltan Fehervari, Tomoyuki Yamaguchi, and Shimon Sakaguchi
- You have accessPreprocalcitonin signal peptide generates a cytotoxic T lymphocyte-defined tumor epitope processed by a proteasome-independent pathwayFaten El Hage, Vincent Stroobant, Isabelle Vergnon, Jean-François Baurain, Hamid Echchakir, Vladimir Lazar, Salem Chouaib, Pierre G. Coulie, and Fathia Mami-Chouaib
Medical Sciences
- You have accessQuantification of the infectious dose of Leishmania major transmitted to the skin by single sand fliesNicola Kimblin, Nathan Peters, Alain Debrabant, Nagila Secundino, Jackson Egen, Phillip Lawyer, Michael P. Fay, Shaden Kamhawi, and David Sacks
See companion article:
- In This Issue- Jul 22, 2008
- You have accessPlant-produced idiotype vaccines for the treatment of non-Hodgkin's lymphoma: Safety and immunogenicity in a phase I clinical studyA. A. McCormick, S. Reddy, S. J. Reinl, T. I. Cameron, D. K. Czerwinkski, F. Vojdani, K. M. Hanley, S. J. Garger, E. L. White, J. Novak, J. Barrett, R. B. Holtz, D. Tusé, and R. Levy
- You have accessA Cre-loxP-based mouse model for conditional somatic gene expression and knockdown in vivo by using avian retroviral vectorsBarbara Seidler, Annegret Schmidt, Ulrich Mayr, Hassan Nakhai, Roland M. Schmid, Günter Schneider, and Dieter Saur
- Open AccessA germ-line-selective advantage rather than an increased mutation rate can explain some unexpectedly common human disease mutationsSoo-Kyung Choi, Song-Ro Yoon, Peter Calabrese, and Norman Arnheim
- You have accessMicrosatellites as EWS/FLI response elements in Ewing's sarcomaKunal Gangwal, Savita Sankar, Peter C. Hollenhorst, Michelle Kinsey, Stephen C. Haroldsen, Atul A. Shah, Kenneth M. Boucher, W. Scott Watkins, Lynn B. Jorde, Barbara J. Graves, and Stephen L. Lessnick
- Open AccessGenomic markers for malignant progression in pulmonary adenocarcinoma with bronchioloalveolar featuresSarit Aviel-Ronen, Bradley P. Coe, Suzanne K. Lau, Gilda da Cunha Santos, Chang-Qi Zhu, Dan Strumpf, Igor Jurisica, Wan L. Lam, and Ming-Sound Tsao
- You have accessGlucose controls CREB activity in islet cells via regulated phosphorylation of TORC2Deidre Jansson, Andy Cheuk-Him Ng, Accalia Fu, Chantal Depatie, Mufida Al Azzabi, and Robert A. Screaton
- You have accessFOXC2 controls Ang-2 expression and modulates angiogenesis, vascular patterning, remodeling, and functions in adipose tissueYuan Xue, Renhai Cao, Daniel Nilsson, Shaohua Chen, Rickard Westergren, Eva-Maria Hedlund, Cecile Martijn, Lena Rondahl, Per Krauli, Erik Walum, Sven Enerbäck, and Yihai Cao
- You have accessA pathogenic dyskerin mutation impairs proliferation and activates a DNA damage response independent of telomere length in miceBai-Wei Gu, Monica Bessler, and Philip J. Mason
- Open AccessFc receptor engagement mediates differentiation of cardiac fibroblast precursor cellsSandra B. Haudek, JoAnn Trial, Ying Xia, Damon Gupta, Darrell Pilling, and Mark L. Entman
- Open AccessSoluble receptor-mediated selective inhibition of VEGFR and PDGFRβ signaling during physiologic and tumor angiogenesisFrank Kuhnert, Betty Y. Y. Tam, Barbara Sennino, John T. Gray, Jenny Yuan, Angeline Jocson, Nihar R. Nayak, Richard C. Mulligan, Donald M. McDonald, and Calvin J. Kuo
Microbiology
- You have accessListeria monocytogenes multidrug resistance transporters activate a cytosolic surveillance pathway of innate immunityGregory T. Crimmins, Anat A. Herskovits, Kai Rehder, Kelsey E. Sivick, Peter Lauer, Thomas W. Dubensky Jr., and Daniel A. Portnoy
- Open AccessThe relationship between dNTP pool levels and mutagenesis in an Escherichia coli NDP kinase mutantJared Nordman and Andrew Wright
- You have accessTwo isozymes of particulate methane monooxygenase with different methane oxidation kinetics are found in Methylocystis sp. strain SC2Mohamed Baani and Werner Liesack
- You have accessRespiratory syncytial virus uses a Vps4-independent budding mechanism controlled by Rab11-FIP2Thomas J. Utley, Nicole A. Ducharme, Vasundhara Varthakavi, Bryan E. Shepherd, Philip J. Santangelo, Michael E. Lindquist, James R. Goldenring, and James E. Crowe Jr.
- You have accessAmide bonds assemble pili on the surface of bacilliJonathan M. Budzik, Luciano A. Marraffini, Puneet Souda, Julian P. Whitelegge, Kym F. Faull, and Olaf Schneewind
- You have accessIn silico identified CCR4 antagonists target regulatory T cells and exert adjuvant activity in vaccinationJagadeesh Bayry, Elma Z. Tchilian, Matthew N. Davies, Emily K. Forbes, Simon J. Draper, Srini V. Kaveri, Adrian V. S. Hill, Michel D. Kazatchkine, Peter C. L. Beverley, Darren R. Flower, and David F. Tough
Neuroscience
- You have accessIdentification of a population of sleep-active cerebral cortex neuronsDmitry Gerashchenko, Jonathan P. Wisor, Deirdre Burns, Rebecca K. Reh, Priyattam J. Shiromani, Takeshi Sakurai, Horacio O. de la Iglesia, and Thomas S. Kilduff
- You have accessWidespread spatial integration in primary somatosensory cortexJamie L. Reed, Pierre Pouget, Hui-Xin Qi, Zhiyi Zhou, Melanie R. Bernard, Mark J. Burish, John Haitas, A. B. Bonds, and Jon H. Kaas
- Open AccessSingle treatment with RNAi against prion protein rescues early neuronal dysfunction and prolongs survival in mice with prion diseaseMelanie D. White, Michael Farmer, Ilaria Mirabile, Sebastian Brandner, John Collinge, and Giovanna R. Mallucci
- You have accessRNA binding activity of the recessive parkinsonism protein DJ-1 supports involvement in multiple cellular pathwaysMarcel P. van der Brug, Jeff Blackinton, Jayanth Chandran, Ling-Yang Hao, Ashish Lal, Krystyna Mazan-Mamczarz, Jennifer Martindale, Chengsong Xie, Rili Ahmad, Kelly J. Thomas, Alexandra Beilina, J. Raphael Gibbs, Jinhui Ding, Amanda J. Myers, Ming Zhan, Huaibin Cai, Nancy M. Bonini, Myriam Gorospe, and Mark R. Cookson
- You have accessInterneuron activity controls endocannabinoid-mediated presynaptic plasticity through calcineurinBoris D. Heifets, Vivien Chevaleyre, and Pablo E. Castillo
Physiology
- You have accessNitrite reductase activity of myoglobin regulates respiration and cellular viability in myocardial ischemia-reperfusion injuryUlrike B. Hendgen-Cotta, Marc W. Merx, Sruti Shiva, Joel Schmitz, Stefanie Becher, Johann P. Klare, Heinz-Jürgen Steinhoff, Axel Goedecke, Jürgen Schrader, Mark T. Gladwin, Malte Kelm, and Tienush Rassaf
Plant Biology
- Open AccessProteome-wide characterization of sugarbeet seed vigor and its tissue specific expressionJulie Catusse, Jean-Marc Strub, Claudette Job, Alain Van Dorsselaer, and Dominique Job
Commentaries
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