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Deficiency in ubiquitin ligase TRIM2 causes accumulation of neurofilament light chain and neurodegeneration
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Edited by Eric R. Kandel, Columbia University, New York, NY, and approved June 11, 2008 (received for review March 5, 2008)

Online Impact
Article Information
- Published in issue August 19, 2008.
- Published first August 7, 2008.
Author Information
- Martin Balastik*,†,‡,
- Francesco Ferraguti§,¶,
- André Pires-da Silva*,‖,
- Tae Ho Lee†,
- Gonzalo Alvarez-Bolado*,
- Kun Ping Lu†, and
- Peter Gruss*,‡
- *Max Planck Institute of Biophysical Chemistry, 37077 Goettingen, Germany;
- §Medical Research Council Anatomical Neuropharmacology Unit, Department of Pharmacology, University of Oxford, Oxford OX1 3TH, United Kingdom;
- ¶Department of Pharmacology, Innsbruck Medical University, A-6020 Innsbruck, Austria;
- ‖Department of Biology, University of Texas, 501 South Nedderman, 337 Life Science, Arlington, TX 76010; and
- †Cancer Biology Program, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115
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Edited by Eric R. Kandel, Columbia University, New York, NY, and approved June 11, 2008 (received for review March 5, 2008)
Footnotes
- ‡To whom correspondence may be addressed. E-mail: mbalasti{at}bidmc.harvard.edu or peter.gruss{at}gv.mpg.de
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Author contributions: M.B., G.A.-B., K.P.L., and P.G. designed research; M.B., F.F., A.P.-d.S., and T.H.L. performed research; T.H.L. contributed new reagents/analytic tools; M.B., F.F., G.A.-B., K.P.L., and P.G. analyzed data; and M.B. and F.F. wrote the paper.
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The authors declare no conflict of interest.
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This article is a PNAS Direct Submission.
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This article contains supporting information online at www.pnas.org/cgi/content/full/0802261105/DCSupplemental.
- © 2008 by The National Academy of Sciences of the USA
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