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Biological Sciences

• Agricultural Sciences

  • Open Access

    Sequence and genetic map of Meloidogyne hapla: A compact nematode genome for plant parasitism

    Charles H. Opperman, David M. Bird, Valerie M. Williamson, Dan S. Rokhsar, Mark Burke, Jonathan Cohn, John Cromer, Steve Diener, Jim Gajan, Steve Graham, T. D. Houfek, Qingli Liu, Therese Mitros, Jennifer Schaff, Reenah Schaffer, Elizabeth Scholl, Bryon R. Sosinski, Varghese P. Thomas, and Eric Windham

    PNAS September 30, 2008 105 (39) 14802-14807; https://doi.org/10.1073/pnas.0805946105

• Applied Biological Sciences

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    Directed evolution of a G protein-coupled receptor for expression, stability, and binding selectivity

    • From the Cover

    Casim A. Sarkar, Igor Dodevski, Manca Kenig, Stefan Dudli, Anja Mohr, Emmanuel Hermans, and Andreas Plückthun

    PNAS September 30, 2008 105 (39) 14808-14813; https://doi.org/10.1073/pnas.0803103105
  • Open Access

    Effective rescue of dystrophin improves cardiac function in dystrophin-deficient mice by a modified morpholino oligomer

    Bo Wu, Hong M. Moulton, Patrick L. Iversen, Jiangang Jiang, Juan Li, Jianbin Li, Christopher F. Spurney, Arpana Sali, Alfredo D. Guerron, Kanneboyina Nagaraju, Timothy Doran, Peijuan Lu, Xiao Xiao, and Qi Long Lu

    PNAS September 30, 2008 105 (39) 14814-14819; https://doi.org/10.1073/pnas.0805676105

• Biochemistry

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    Rifamycins do not function by allosteric modulation of binding of Mg²⁺ to the RNA polymerase active center

    Andrey Feklistov, Vladimir Mekler, Qiaorong Jiang, Lars F. Westblade, Herbert Irschik, Rolf Jansen, Arkady Mustaev, Seth A. Darst, and Richard H. Ebright

    PNAS September 30, 2008 105 (39) 14820-14825; https://doi.org/10.1073/pnas.0802822105
  • Open Access

    Control of feeding behavior in C. elegans by human G protein-coupled receptors permits screening for agonist-expressing bacteria

    Michelle S. Teng, Paul Shadbolt, Andrew G. Fraser, Gert Jansen, and John McCafferty

    PNAS September 30, 2008 105 (39) 14826-14831; https://doi.org/10.1073/pnas.0803290105
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    The crystal structure of MexR from Pseudomonas aeruginosa in complex with its antirepressor ArmR

    Mark S. Wilke, Markus Heller, A. Louise Creagh, Charles A. Haynes, Lawrence P. McIntosh, Keith Poole, and Natalie C. J. Strynadka

    PNAS September 30, 2008 105 (39) 14832-14837; https://doi.org/10.1073/pnas.0805489105
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    The Saccharomyces cerevisiae linker histone Hho1p is essential for chromatin compaction in stationary phase and is displaced by transcription

    Georgia Schäfer, Christopher R. E. McEvoy, and Hugh-G. Patterton

    PNAS September 30, 2008 105 (39) 14838-14843; https://doi.org/10.1073/pnas.0806337105
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    Backtracking on the folding landscape of the β-trefoil protein interleukin-1β?

    Dominique T. Capraro, Melinda Roy, José N. Onuchic, and Patricia A. Jennings

    PNAS September 30, 2008 105 (39) 14844-14848; https://doi.org/10.1073/pnas.0807812105
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    Discovery of posttranslational maturation by self-subunit swapping

    Zhemin Zhou, Yoshiteru Hashimoto, Kentaro Shiraki, and Michihiko Kobayashi

    PNAS September 30, 2008 105 (39) 14849-14854; https://doi.org/10.1073/pnas.0803428105

• Biophysics

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    Kinetic regulation of coated vesicle secretion

    Lionel Foret and Pierre Sens

    PNAS September 30, 2008 105 (39) 14763-14768; https://doi.org/10.1073/pnas.0801173105
  • Open Access

    Modeling the chemotactic response of Escherichia coli to time-varying stimuli

    Yuhai Tu, Thomas S. Shimizu, and Howard C. Berg

    PNAS September 30, 2008 105 (39) 14855-14860; https://doi.org/10.1073/pnas.0807569105

• Cell Biology

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    Mitochondrial potassium channel Kv1.3 mediates Bax-induced apoptosis in lymphocytes

    Ildikò Szabó, Jürgen Bock, Heike Grassmé, Matthias Soddemann, Barbara Wilker, Florian Lang, Mario Zoratti, and Erich Gulbins

    PNAS September 30, 2008 105 (39) 14861-14866; https://doi.org/10.1073/pnas.0804236105
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    Sustained induction of epithelial to mesenchymal transition activates DNA methylation of genes silenced in basal-like breast cancers

    Nancy Dumont, Matthew B. Wilson, Yongping G. Crawford, Paul A. Reynolds, Mahvash Sigaroudinia, and Thea D. Tlsty

    PNAS September 30, 2008 105 (39) 14867-14872; https://doi.org/10.1073/pnas.0807146105
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    RNAi screening for kinases and phosphatases identifies FoxO regulators

    Jaakko Mattila, Jukka Kallijärvi, and Oscar Puig

    PNAS September 30, 2008 105 (39) 14873-14878; https://doi.org/10.1073/pnas.0803022105
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    A search for conserved sequences in coding regions reveals that the let-7 microRNA targets Dicer within its coding sequence

    Joshua J. Forman, Aster Legesse-Miller, and Hilary A. Coller

    PNAS September 30, 2008 105 (39) 14879-14884; https://doi.org/10.1073/pnas.0803230105
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    Computational prediction of RNA structural motifs involved in posttranscriptional regulatory processes

    Michal Rabani, Michael Kertesz, and Eran Segal

    PNAS September 30, 2008 105 (39) 14885-14890; https://doi.org/10.1073/pnas.0803169105

• Developmental Biology

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    The mammary microenvironment alters the differentiation repertoire of neural stem cells

    Brian W. Booth, David L. Mack, Andreas Androutsellis-Theotokis, Ronald D. G. McKay, Corinne A. Boulanger, and Gilbert H. Smith

    PNAS September 30, 2008 105 (39) 14891-14896; https://doi.org/10.1073/pnas.0803214105
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    Boundaries of Dachsous Cadherin activity modulate the Hippo signaling pathway to induce cell proliferation

    • From the Cover

    Maria Willecke, Fisun Hamaratoglu, Leticia Sansores-Garcia, Chunyao Tao, and Georg Halder

    PNAS September 30, 2008 105 (39) 14897-14902; https://doi.org/10.1073/pnas.0805201105

• Ecology

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    Self-made shelters protect spiders from predation

    • From the Cover

    Carryn Manicom, Lin Schwarzkopf, Ross A. Alford, and Thomas W. Schoener

    PNAS September 30, 2008 105 (39) 14903-14907; https://doi.org/10.1073/pnas.0807107105
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    Opening the climate envelope reveals no macroscale associations with climate in European birds

    Colin M. Beale, Jack J. Lennon, and Alessandro Gimona

    PNAS September 30, 2008 105 (39) 14908-14912; https://doi.org/10.1073/pnas.0803506105

• Evolution

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    Newly discovered sister lineage sheds light on early ant evolution

    Christian Rabeling, Jeremy M. Brown, and Manfred Verhaagh

    PNAS September 30, 2008 105 (39) 14913-14917; https://doi.org/10.1073/pnas.0806187105
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    Drug interactions modulate the potential for evolution of resistance

    Jean-Baptiste Michel, Pamela J. Yeh, Remy Chait, Robert C. Moellering Jr., and Roy Kishony

    PNAS September 30, 2008 105 (39) 14918-14923; https://doi.org/10.1073/pnas.0800944105
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    Prevolutionary dynamics and the origin of evolution

    Martin A. Nowak and Hisashi Ohtsuki

    PNAS September 30, 2008 105 (39) 14924-14927; https://doi.org/10.1073/pnas.0806714105
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    Adaptive changes in the transcription factor HoxA-11 are essential for the evolution of pregnancy in mammals

    Vincent J. Lynch, Andrea Tanzer, Yajun Wang, Frederick C. Leung, Birgit Gellersen, Deena Emera, and Gunter P. Wagner

    PNAS September 30, 2008 105 (39) 14928-14933; https://doi.org/10.1073/pnas.0802355105
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    Endosymbiont gene functions impaired and rescued by polymerase infidelity at poly(A) tracts

    Ivica Tamas, Jennifer J. Wernegreen, Björn Nystedt, Seth N. Kauppinen, Alistair C. Darby, Laura Gomez-Valero, Daniel Lundin, Anthony M. Poole, and Siv G. E. Andersson

    PNAS September 30, 2008 105 (39) 14934-14939; https://doi.org/10.1073/pnas.0806554105

• Genetics

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    A common variant in the 3′UTR of the GRIK4 glutamate receptor gene affects transcript abundance and protects against bipolar disorder

    B. S. Pickard, H. M. Knight, R. S. Hamilton, D. C. Soares, R. Walker, J. K. F. Boyd, J. Machell, A. Maclean, K. A. McGhee, A. Condie, D. J. Porteous, D. St. Clair, I. Davis, D. H. R. Blackwood, and W. J. Muir

    PNAS September 30, 2008 105 (39) 14940-14945; https://doi.org/10.1073/pnas.0800643105
  • Open Access

    Analysis and synthesis of high-amplitude Cis-elements in the mammalian circadian clock

    Yuichi Kumaki, Maki Ukai-Tadenuma, Ken-ichiro D. Uno, Junko Nishio, Koh-hei Masumoto, Mamoru Nagano, Takashi Komori, Yasufumi Shigeyoshi, John B. Hogenesch, and Hiroki R. Ueda

    PNAS September 30, 2008 105 (39) 14946-14951; https://doi.org/10.1073/pnas.0802636105
  • Open Access

    Salmonella pathogenesis reveals that BMP signaling regulates blood cell homeostasis and immune responses in Drosophila

    Joel L. Frandsen, Bronwyn Gunn, Selen Muratoglu, Nancy Fossett, and Stuart J. Newfeld

    PNAS September 30, 2008 105 (39) 14952-14957; https://doi.org/10.1073/pnas.0808208105
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    Distinct size distribution of endogenous siRNAs in maize: Evidence from deep sequencing in the mop1-1 mutant

    Kan Nobuta, Cheng Lu, Roli Shrivastava, Manoj Pillay, Emanuele De Paoli, Monica Accerbi, Mario Arteaga-Vazquez, Lyudmila Sidorenko, Dong-Hoon Jeong, Yang Yen, Pamela J. Green, Vicki L. Chandler, and Blake C. Meyers

    PNAS September 30, 2008 105 (39) 14958-14963; https://doi.org/10.1073/pnas.0808066105
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    piRNA-mediated nuclear accumulation of retrotransposon transcripts in the Drosophila female germline

    Séverine Chambeyron, Anna Popkova, Geneviève Payen-Groschêne, Christine Brun, Dorsaf Laouini, Alain Pelisson, and Alain Bucheton

    PNAS September 30, 2008 105 (39) 14964-14969; https://doi.org/10.1073/pnas.0805943105
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    The stem rust resistance gene Rpg5 encodes a protein with nucleotide-binding-site, leucine-rich, and protein kinase domains

    R. Brueggeman, A. Druka, J. Nirmala, T. Cavileer, T. Drader, N. Rostoks, A. Mirlohi, H. Bennypaul, U. Gill, D. Kudrna, C. Whitelaw, A. Kilian, F. Han, Y. Sun, K. Gill, B. Steffenson, and A. Kleinhofs

    PNAS September 30, 2008 105 (39) 14970-14975; https://doi.org/10.1073/pnas.0807270105
  • Open Access

    Stra8 and its inducer, retinoic acid, regulate meiotic initiation in both spermatogenesis and oogenesis in mice

    Ericka L. Anderson, Andrew E. Baltus, Hermien L. Roepers-Gajadien, Terry J. Hassold, Dirk G. de Rooij, Ans M. M. van Pelt, and David C. Page

    PNAS September 30, 2008 105 (39) 14976-14980; https://doi.org/10.1073/pnas.0807297105

• Immunology

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    Chemical targeting of the innate antiviral response by histone deacetylase inhibitors renders refractory cancers sensitive to viral oncolysis

    Thi Lien-Anh Nguyên, Hesham Abdelbary, Meztli Arguello, Caroline Breitbach, Simon Leveille, Jean-Simon Diallo, Amber Yasmeen, Tarek A. Bismar, David Kirn, Theresa Falls, Valerie E. Snoulten, Barbara C. Vanderhyden, Joel Werier, Harold Atkins, Markus J. V. Vähä-Koskela, David F. Stojdl, John C. Bell, and John Hiscott

    PNAS September 30, 2008 105 (39) 14981-14986; https://doi.org/10.1073/pnas.0803988105
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    CTLA-4 blockade increases IFNγ-producing CD4⁺ICOS^hi cells to shift the ratio of effector to regulatory T cells in cancer patients

    Chrysoula I. Liakou, Ashish Kamat, Derek Ng Tang, Hong Chen, Jingjing Sun, Patricia Troncoso, Christopher Logothetis, and Padmanee Sharma

    PNAS September 30, 2008 105 (39) 14987-14992; https://doi.org/10.1073/pnas.0806075105
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    Local BAFF gene silencing suppresses Th17-cell generation and ameliorates autoimmune arthritis

    Queenie Lai Kwan Lam, Otis King Hung Ko, Bo-Jian Zheng, and Liwei Lu

    PNAS September 30, 2008 105 (39) 14993-14998; https://doi.org/10.1073/pnas.0806044105
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    Respiratory syncytial virus impairs T cell activation by preventing synapse assembly with dendritic cells

    Pablo A. González, Carolina E. Prado, Eduardo D. Leiva, Leandro J. Carreño, Susan M. Bueno, Claudia A. Riedel, and Alexis M. Kalergis

    PNAS September 30, 2008 105 (39) 14999-15004; https://doi.org/10.1073/pnas.0802555105
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    In vivo enzymatic modulation of IgG glycosylation inhibits autoimmune disease in an IgG subclass-dependent manner

    Heike Albert, Mattias Collin, Diana Dudziak, Jeffrey V. Ravetch, and Falk Nimmerjahn

    PNAS September 30, 2008 105 (39) 15005-15009; https://doi.org/10.1073/pnas.0808248105
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    Distinct sets of αβ TCRs confer similar recognition of tumor antigen NY-ESO-1_157–165 by interacting with its central Met/Trp residues

    Laurent Derré, Marc Bruyninx, Petra Baumgaertner, Mathias Ferber, Daphné Schmid, Antoine Leimgruber, Vincent Zoete, Pedro Romero, Olivier Michielin, Daniel E. Speiser, and Nathalie Rufer

    PNAS September 30, 2008 105 (39) 15010-15015; https://doi.org/10.1073/pnas.0807954105
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    Selective expansion of a subset of exhausted CD8 T cells by αPD-L1 blockade

    Shawn D. Blackburn, Haina Shin, Gordon J. Freeman, and E. John Wherry

    PNAS September 30, 2008 105 (39) 15016-15021; https://doi.org/10.1073/pnas.0801497105
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    NF-IL6 (C/EBPβ) induces HIV-1 replication by inhibiting cytidine deaminase APOBEC3G

    Shigemi M. Kinoshita and Shizuka Taguchi

    PNAS September 30, 2008 105 (39) 15022-15027; https://doi.org/10.1073/pnas.0807269105
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    Inflammation and autoimmunity caused by a SHP1 mutation depend on IL-1, MyD88, and a microbial trigger

    Ben A. Croker, Brian R. Lawson, Sophie Rutschmann, Michael Berger, Celine Eidenschenk, Amanda L. Blasius, Eva Marie Y. Moresco, Sosathya Sovath, Louise Cengia, Leonard D. Shultz, Argyrios N. Theofilopoulos, Sven Pettersson, and Bruce Alan Beutler

    PNAS September 30, 2008 105 (39) 15028-15033; https://doi.org/10.1073/pnas.0806619105

• Medical Sciences

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    Preneoplastic lesion growth driven by the death of adjacent normal stem cells

    Dennis L. Chao, J. Thomas Eck, Douglas E. Brash, Carlo C. Maley, and E. Georg Luebeck

    PNAS September 30, 2008 105 (39) 15034-15039; https://doi.org/10.1073/pnas.0802211105
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    Identification of amino acids essential for the antiangiogenic activity of tumstatin and its use in combination antitumor activity

    Hans Petter Eikesdal, Hikaru Sugimoto, Gabriel Birrane, Yohei Maeshima, Vesselina G. Cooke, Mark Kieran, and Raghu Kalluri

    PNAS September 30, 2008 105 (39) 15040-15045; https://doi.org/10.1073/pnas.0807055105
  • Open Access

    AP4 encodes a c-MYC-inducible repressor of p21

    Peter Jung, Antje Menssen, Doris Mayr, and Heiko Hermeking

    PNAS September 30, 2008 105 (39) 15046-15051; https://doi.org/10.1073/pnas.0801773105
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    Pancreatic exocrine insufficiency in LXRβ^−/− mice is associated with a reduction in aquaporin-1 expression

    Chiara Gabbi, Hyun-Jin Kim, Kjell Hultenby, Didier Bouton, Gudrun Toresson, Margaret Warner, and Jan-Åke Gustafsson

    PNAS September 30, 2008 105 (39) 15052-15057; https://doi.org/10.1073/pnas.0808097105
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    Opposing functions of IKKβ during acute and chronic intestinal inflammation

    Lars Eckmann, Tim Nebelsiek, Alexander A. Fingerle, Sara M. Dann, Jörg Mages, Roland Lang, Sylvie Robine, Martin F. Kagnoff, Roland M. Schmid, Michael Karin, Melek C. Arkan, and Florian R. Greten

    PNAS September 30, 2008 105 (39) 15058-15063; https://doi.org/10.1073/pnas.0808216105
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    The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria

    Malin E. V. Johansson, Mia Phillipson, Joel Petersson, Anna Velcich, Lena Holm, and Gunnar C. Hansson

    PNAS September 30, 2008 105 (39) 15064-15069; https://doi.org/10.1073/pnas.0803124105

• Microbiology

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    A polymicrobial perspective of pulmonary infections exposes an enigmatic pathogen in cystic fibrosis patients

    Christopher D. Sibley, Michael D. Parkins, Harvey R. Rabin, Kangmin Duan, Jens C. Norgaard, and Michael G. Surette

    PNAS September 30, 2008 105 (39) 15070-15075; https://doi.org/10.1073/pnas.0804326105
  • Open Access

    The convergence of carbohydrate active gene repertoires in human gut microbes

    Catherine A. Lozupone, Micah Hamady, Brandi L. Cantarel, Pedro M. Coutinho, Bernard Henrissat, Jeffrey I. Gordon, and Rob Knight

    PNAS September 30, 2008 105 (39) 15076-15081; https://doi.org/10.1073/pnas.0807339105
  • Open Access

    Role of selection in the emergence of lineages and the evolution of virulence in Neisseria meningitidis

    Caroline O. Buckee, Keith A. Jolley, Mario Recker, Bridget Penman, Paula Kriz, Sunetra Gupta, and Martin C. J. Maiden

    PNAS September 30, 2008 105 (39) 15082-15087; https://doi.org/10.1073/pnas.0712019105
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    An insect symbiosis is influenced by bacterium-specific polymorphisms in outer-membrane protein A

    Brian L. Weiss, Yineng Wu, Jonathon J. Schwank, Nicholas S. Tolwinski, and Serap Aksoy

    PNAS September 30, 2008 105 (39) 15088-15093; https://doi.org/10.1073/pnas.0805666105
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    The genome of Cyanothece 51142, a unicellular diazotrophic cyanobacterium important in the marine nitrogen cycle

    Eric A. Welsh, Michelle Liberton, Jana Stöckel, Thomas Loh, Thanura Elvitigala, Chunyan Wang, Aye Wollam, Robert S. Fulton, Sandra W. Clifton, Jon M. Jacobs, Rajeev Aurora, Bijoy K. Ghosh, Louis A. Sherman, Richard D. Smith, Richard K. Wilson, and Himadri B. Pakrasi

    PNAS September 30, 2008 105 (39) 15094-15099; https://doi.org/10.1073/pnas.0805418105
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    A channel connecting the mother cell and forespore during bacterial endospore formation

    Jeffrey Meisner, Xin Wang, Monica Serrano, Adriano O. Henriques, and Charles P. Moran Jr

    PNAS September 30, 2008 105 (39) 15100-15105; https://doi.org/10.1073/pnas.0806301105

• Neuroscience

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    Age-related changes in midbrain dopaminergic regulation of the human reward system

    • From the Cover

    Jean-Claude Dreher, Andreas Meyer-Lindenberg, Philip Kohn, and Karen Faith Berman

    PNAS September 30, 2008 105 (39) 15106-15111; https://doi.org/10.1073/pnas.0802127105
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    Human gene therapy for RPE65 isomerase deficiency activates the retinoid cycle of vision but with slow rod kinetics

    Artur V. Cideciyan, Tomas S. Aleman, Sanford L. Boye, Sharon B. Schwartz, Shalesh Kaushal, Alejandro J. Roman, Ji-jing Pang, Alexander Sumaroka, Elizabeth A. M. Windsor, James M. Wilson, Terence R. Flotte, Gerald A. Fishman, Elise Heon, Edwin M. Stone, Barry J. Byrne, Samuel G. Jacobson, and William W. Hauswirth

    PNAS September 30, 2008 105 (39) 15112-15117; https://doi.org/10.1073/pnas.0807027105
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    Adenosine receptor antagonists alter the stability of human epileptic GABA_A receptors

    Cristina Roseti, Katiuscia Martinello, Sergio Fucile, Vanessa Piccari, Addolorata Mascia, Giancarlo Di Gennaro, Pier Paolo Quarato, Mario Manfredi, Vincenzo Esposito, Gianpaolo Cantore, Antonella Arcella, Michele Simonato, Bertil B. Fredholm, Cristina Limatola, Ricardo Miledi, and Fabrizio Eusebi

    PNAS September 30, 2008 105 (39) 15118-15123; https://doi.org/10.1073/pnas.0807277105
  • Open Access

    Mutational analysis of the neurexin/neuroligin complex reveals essential and regulatory components

    Carsten Reissner, Martin Klose, Richard Fairless, and Markus Missler

    PNAS September 30, 2008 105 (39) 15124-15129; https://doi.org/10.1073/pnas.0801639105
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    cAMP/PKA signaling and RIM1α mediate presynaptic LTP in the lateral amygdala

    Elodie Fourcaudot, Frédéric Gambino, Yann Humeau, Guillaume Casassus, Hamdy Shaban, Bernard Poulain, and Andreas Lüthi

    PNAS September 30, 2008 105 (39) 15130-15135; https://doi.org/10.1073/pnas.0806938105
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    Mitochondrial complex I inhibition is not required for dopaminergic neuron death induced by rotenone, MPP⁺, or paraquat

    Won-Seok Choi, Shane E. Kruse, Richard D. Palmiter, and Zhengui Xia

    PNAS September 30, 2008 105 (39) 15136-15141; https://doi.org/10.1073/pnas.0807581105
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    Disulfide locking a sodium channel voltage sensor reveals ion pair formation during activation

    Paul G. DeCaen, Vladimir Yarov-Yarovoy, Yong Zhao, Todd Scheuer, and William A. Catterall

    PNAS September 30, 2008 105 (39) 15142-15147; https://doi.org/10.1073/pnas.0806486105
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    Estrogens directly potentiate neuronal L-type Ca²⁺ channels

    Saumyendra N. Sarkar, Ren-Qi Huang, Shaun M. Logan, Kun Don Yi, Glenn H. Dillon, and James W. Simpkins

    PNAS September 30, 2008 105 (39) 15148-15153; https://doi.org/10.1073/pnas.0802379105
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    The BK-mediated fAHP is modulated by learning a hippocampus-dependent task

    Elizabeth A. Matthews, Aldis P. Weible, Samit Shah, and John F. Disterhoft

    PNAS September 30, 2008 105 (39) 15154-15159; https://doi.org/10.1073/pnas.0805855105
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    Spontaneous neural activity during human slow wave sleep

    Thien Thanh Dang-Vu, Manuel Schabus, Martin Desseilles, Geneviève Albouy, Mélanie Boly, Annabelle Darsaud, Steffen Gais, Géraldine Rauchs, Virginie Sterpenich, Gilles Vandewalle, Julie Carrier, Gustave Moonen, Evelyne Balteau, Christian Degueldre, André Luxen, Christophe Phillips, and Pierre Maquet

    PNAS September 30, 2008 105 (39) 15160-15165; https://doi.org/10.1073/pnas.0801819105

• Pharmacology

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    Fabrication of ZnPc/protein nanohorns for double photodynamic and hyperthermic cancer phototherapy

    Minfang Zhang, Tatsuya Murakami, Kumiko Ajima, Kunihiro Tsuchida, Atula S. D. Sandanayaka, Osamu Ito, Sumio Iijima, and Masako Yudasaka

    PNAS September 30, 2008 105 (39) 14773-14778; https://doi.org/10.1073/pnas.0801349105
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    Superoxide anions regulate TORC1 and its ability to bind Fpr1:rapamycin complex

    Taavi K. Neklesa and Ronald W. Davis

    PNAS September 30, 2008 105 (39) 15166-15171; https://doi.org/10.1073/pnas.0807712105

• Physiology

  • Open Access

    Physiological significance of a peripheral tissue circadian clock

    • From the Cover

    Katja A. Lamia, Kai-Florian Storch, and Charles J. Weitz

    PNAS September 30, 2008 105 (39) 15172-15177; https://doi.org/10.1073/pnas.0806717105

• Plant Biology

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    Tetrapyrrole profiling in Arabidopsis seedlings reveals that retrograde plastid nuclear signaling is not due to Mg-protoporphyrin IX accumulation

    Michael Moulin, Alex C. McCormac, Matthew J. Terry, and Alison G. Smith

    PNAS September 30, 2008 105 (39) 15178-15183; https://doi.org/10.1073/pnas.0803054105
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    The steady-state level of Mg-protoporphyrin IX is not a determinant of plastid-to-nucleus signaling in Arabidopsis

    Nobuyoshi Mochizuki, Ryouichi Tanaka, Ayumi Tanaka, Tatsuru Masuda, and Akira Nagatani

    PNAS September 30, 2008 105 (39) 15184-15189; https://doi.org/10.1073/pnas.0803245105
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    New auxin analogs with growth-promoting effects in intact plants reveal a chemical strategy to improve hormone delivery

    Sigal Savaldi-Goldstein, Thomas J. Baiga, Florence Pojer, Tsegeye Dabi, Cristina Butterfield, Geraint Parry, Aaron Santner, Nihal Dharmasiri, Yi Tao, Mark Estelle, Joseph P. Noel, and Joanne Chory

    PNAS September 30, 2008 105 (39) 15190-15195; https://doi.org/10.1073/pnas.0806324105
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    sparse inflorescence1 encodes a monocot-specific YUCCA-like gene required for vegetative and reproductive development in maize

    Andrea Gallavotti, Solmaz Barazesh, Simon Malcomber, Darren Hall, David Jackson, Robert J. Schmidt, and Paula McSteen

    PNAS September 30, 2008 105 (39) 15196-15201; https://doi.org/10.1073/pnas.0805596105
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    Evolutionary linkage between eukaryotic cytokinesis and chloroplast division by dynamin proteins

    Shin-ya Miyagishima, Hidekazu Kuwayama, Hideko Urushihara, and Hiromitsu Nakanishi

    PNAS September 30, 2008 105 (39) 15202-15207; https://doi.org/10.1073/pnas.0802412105
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