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Table of Contents
October 28, 2008; vol. 105 no. 43
This Week in PNAS
Letters (Online Only)
- You have accessThe meaning of “macaque” facial expressionsElisabeth H. M. Sterck and Brigitte M. A. Goossens
See companion article:
- You have accessReply to Sterck and Goossens: Perception of facial expressions in rhesus macaquesFadila Hadj-Bouziane, Andrew H. Bell, Leslie G. Ungerleider, and Roger B. H. Tootell
See companion article:
- The meaning of “macaque” facial expressions- Oct 22, 2008
Profile
- You have accessProfile of Ellen D. WilliamsFarooq Ahmed
See companion article:
- Dynamic interfaces in an organic thin film- Sep 02, 2008
Physical Sciences
Applied Physical Sciences
- You have accessDynamic interfaces in an organic thin film
- Inaugural Article
Chenggang Tao, Qiang Liu, Blake C. Riddick, William G. Cullen, Janice Reutt-Robey, John D. Weeks, and Ellen D. Williams
Chemistry
- You have accessStability and structural recovery of the tetramerization domain of p53-R337H mutant induced by a designed templating ligandSusana Gordo, Vera Martos, Eva Santos, Margarita Menéndez, Carles Bo, Ernest Giralt, and Javier de Mendoza
- Open AccessNMR studies of a channel protein without membranes: Structure and dynamics of water-solubilized KcsADejian Ma, Tommy S. Tillman, Pei Tang, Eva Meirovitch, Roderic Eckenhoff, Anna Carnini, and Yan Xu
- You have accessAtomic detail of chemical transformation at the transition state of an enzymatic reactionSuwipa Saen-oon, Sara Quaytman-Machleder, Vern L. Schramm, and Steven D. Schwartz
- You have accessHow the thymus designs antigen-specific and self-tolerant T cell receptor sequencesAndrej Košmrlj, Abhishek K. Jha, Eric S. Huseby, Mehran Kardar, and Arup K. Chakraborty
Engineering
- You have accessDynamics of shear-induced ATP release from red blood cellsJiandi Wan, William D. Ristenpart, and Howard A. Stone
- You have accessElectric field-induced direct delivery of proteins by a nanofountain probeOwen Y. Loh, Andrea M. Ho, Jee E. Rim, Punit Kohli, Neelesh A. Patankar, and Horacio D. Espinosa
Geology
- You have accessA humid corridor across the Sahara for the migration of early modern humans out of Africa 120,000 years agoAnne H. Osborne, Derek Vance, Eelco J. Rohling, Nick Barton, Mike Rogerson, and Nuri Fello
Physics
- You have accessManaging light polarization via plasmon–molecule interactions within an asymmetric metal nanoparticle trimerTimur Shegai, Zhipeng Li, Tali Dadosh, Zhenyu Zhang, Hongxing Xu, and Gilad Haran
- You have accessCrystal structure of the pressure-induced metallic phase of SiH4 from ab initio theoryD. Y. Kim, R. H. Scheicher, S. Lebègue, J. Prasongkit, B. Arnaud, M. Alouani, and R. Ahuja
Social Sciences
Anthropology
- You have accessHigh-precision radiocarbon dating and historical biblical archaeology in southern JordanThomas E. Levy, Thomas Higham, Christopher Bronk Ramsey, Neil G. Smith, Erez Ben-Yosef, Mark Robinson, Stefan Münger, Kyle Knabb, Jürgen P. Schulze, Mohammad Najjar, and Lisa Tauxe
See companion article:
- In This Issue- Oct 28, 2008
Social Sciences
- You have accessAsymmetric disassembly and robustness in declining networks
- From the Cover
Serguei Saavedra, Felix Reed-Tsochas, and Brian Uzzi
Biological Sciences
Applied Biological Sciences
- You have accessKinase requirements in human cells: I. Comparing kinase requirements across various cell typesDorre A. Grueneberg, Sebastien Degot, Joseph Pearlberg, Wenliang Li, Joan E. Davies, Amy Baldwin, Wilson Endege, John Doench, Jacqueline Sawyer, Yanhui Hu, Frederick Boyce, Jun Xian, Karl Munger, and Ed Harlow
- You have accessKinase requirements in human cells: II. Genetic interaction screens identify kinase requirements following HPV16 E7 expression in cancer cellsAmy Baldwin, Wenliang Li, Miranda Grace, Joseph Pearlberg, Ed Harlow, Karl Münger, and Dorre A. Grueneberg
- You have accessKinase requirements in human cells: III. Altered kinase requirements in VHL−/− cancer cells detected in a pilot synthetic lethal screenArchana Bommi-Reddy, Ingrid Almeciga, Jacqueline Sawyer, Christoph Geisen, Wenliang Li, Ed Harlow, William G. Kaelin Jr, and Dorre A. Grueneberg
- You have accessKinase requirements in human cells: IV. Differential kinase requirements in cervical and renal human tumor cell linesDorre A. Grueneberg, Wenliang Li, Joan E. Davies, Jacqueline Sawyer, Joseph Pearlberg, and Ed Harlow
Biochemistry
- You have accessAdaptive antioxidant methionine accumulation in respiratory chain complexes explains the use of a deviant genetic code in mitochondria
- From the Cover
Aline Bender, Parvana Hajieva, and Bernd Moosmann - You have accessQuality control despite mistranslation caused by an ambiguous genetic codeBenfang Ruan, Sotiria Palioura, Jeffrey Sabina, Laure Marvin-Guy, Sunil Kochhar, Robert A. LaRossa, and Dieter Söll
- You have accessActivities of human exonuclease 1 that promote cleavage of transcribed immunoglobulin switch regionsAarthy C. Vallur and Nancy Maizels
- You have accessTransport of LDL-derived cholesterol from the NPC1 compartment to the ER involves the trans-Golgi network and the SNARE protein complexYasuomi Urano, Hiroshi Watanabe, Stephanie R. Murphy, Yohei Shibuya, Yong Geng, Andrew A. Peden, Catherine C. Y. Chang, and Ta Yuan Chang
- You have accessInsights into the structural dynamics of the Hsp110–Hsp70 interaction reveal the mechanism for nucleotide exchange activityClaes Andréasson, Jocelyne Fiaux, Heike Rampelt, Silke Druffel-Augustin, and Bernd Bukau
- Open AccessProlonged signaling at the parathyroid hormone receptor by peptide ligands targeted to a specific receptor conformationMakoto Okazaki, Sebastien Ferrandon, Jean-Pierre Vilardaga, Mary L. Bouxsein, John T. Potts Jr, and Thomas J. Gardella
- You have accessDynamic stabilization of actin filamentsHao Yuan Kueh, William M. Brieher, and Timothy J. Mitchison
Biophysics
- You have accessStability and structural recovery of the tetramerization domain of p53-R337H mutant induced by a designed templating ligandSusana Gordo, Vera Martos, Eva Santos, Margarita Menéndez, Carles Bo, Ernest Giralt, and Javier de Mendoza
- You have accessDynamics of shear-induced ATP release from red blood cellsJiandi Wan, William D. Ristenpart, and Howard A. Stone
- Open AccessNMR studies of a channel protein without membranes: Structure and dynamics of water-solubilized KcsADejian Ma, Tommy S. Tillman, Pei Tang, Eva Meirovitch, Roderic Eckenhoff, Anna Carnini, and Yan Xu
- You have accessAtomic detail of chemical transformation at the transition state of an enzymatic reactionSuwipa Saen-oon, Sara Quaytman-Machleder, Vern L. Schramm, and Steven D. Schwartz
- You have accessSide-chain recognition and gating in the ribosome exit tunnelPaula M. Petrone, Christopher D. Snow, Del Lucent, and Vijay S. Pande
- Open AccessRole of HAMP domains in chemotaxis signaling by bacterial chemoreceptorsCezar M. Khursigara, Xiongwu Wu, Peijun Zhang, Jonathan Lefman, and Sriram Subramaniam
- You have accessCrystallographic structure of xanthorhodopsin, the light-driven proton pump with a dual chromophoreHartmut Luecke, Brigitte Schobert, Jason Stagno, Eleonora S. Imasheva, Jennifer M. Wang, Sergei P. Balashov, and Janos K. Lanyi
- You have accessUsing diastereopeptides to control metal ion coordination in proteinsAnna F. A. Peacock, Lars Hemmingsen, and Vincent L. Pecoraro
Cell Biology
- Open AccessDifferent polycomb group CBX family proteins associate with distinct regions of chromatin using nonhomologous protein sequencesClaudius Vincenz and Tom K. Kerppola
- You have accessHuman DNA polymerase η activity and translocation is regulated by phosphorylationYih-wen Chen, James E. Cleaver, Zafer Hatahet, Richard E. Honkanen, Jang-Yang Chang, Yun Yen, and Kai-ming Chou
- Open AccessNuclear Akt interacts with B23/NPM and protects it from proteolytic cleavage, enhancing cell survivalSang Bae Lee, Truong L. Xuan Nguyen, Joung Woo Choi, Kyung-Hoon Lee, Sung-Woo Cho, Zhixue Liu, Keqiang Ye, Sun Sik Bae, and Jee-Yin Ahn
- You have accessAcid phosphatase 5 is responsible for removing the mannose 6-phosphate recognition marker from lysosomal proteinsPengling Sun, David E. Sleat, Michèle Lecocq, Alison R. Hayman, Michel Jadot, and Peter Lobel
- You have accessSpecificity of the J-protein Sis1 in the propagation of 3 yeast prionsTakashi Higurashi, Justin K. Hines, Chandan Sahi, Rebecca Aron, and Elizabeth A. Craig
- You have accessA bacterial control circuit integrates polar localization and proteolysis of key regulatory proteins with a phospho-signaling cascadeAntonio A. Iniesta and Lucy Shapiro
Developmental Biology
- You have accessModulation of potassium channel function confers a hyperproliferative invasive phenotype on embryonic stem cellsJunji Morokuma, Douglas Blackiston, Dany S. Adams, Guiscard Seebohm, Barry Trimmer, and Michael Levin
- Open AccessAncestral Notch-mediated segmentation revealed in the cockroach Periplaneta americana
- From the Cover
J. I. Pueyo, R. Lanfear, and J. P. CousoSee companion article:
- The molecular ancestry of segmentation mechanisms- Oct 23, 2008
- You have accessLoss of ephrin-A5 function disrupts lens fiber cell packing and leads to cataractMargaret A. Cooper, Alexander I. Son, Daniel Komlos, Yuhai Sun, Norman J. Kleiman, and Renping Zhou
- Open AccessMesothelium contributes to vascular smooth muscle and mesenchyme during lung developmentJianwen Que, Bettina Wilm, Hiroshi Hasegawa, Fan Wang, David Bader, and Brigid L. M. Hogan
See companion article:
- In This Issue- Oct 28, 2008
Ecology
- You have accessAsymmetric disassembly and robustness in declining networks
- From the Cover
Serguei Saavedra, Felix Reed-Tsochas, and Brian Uzzi
Evolution
- You have accessHindwings are unnecessary for flight but essential for execution of normal evasive flight in LepidopteraBenjamin Jantzen and Thomas Eisner
- You have accessMolecular phylogeny of choanoflagellates, the sister group to MetazoaM. Carr, B. S. C. Leadbeater, R. Hassan, M. Nelson, and S. L. Baldauf
- You have accessEvolutionary redefinition of immunoglobulin light chain isotypes in tetrapods using molecular markersSabyasachi Das, Nikolas Nikolaidis, Jan Klein, and Masatoshi Nei
Genetics
- Open AccessSignificant conservation of synthetic lethal genetic interaction networks between distantly related eukaryotesScott J. Dixon, Yaroslav Fedyshyn, Judice L. Y. Koh, T. S. Keshava Prasad, Charly Chahwan, Gordon Chua, Kiana Toufighi, Anastasija Baryshnikova, Jacqueline Hayles, Kwang-Lae Hoe, Dong-Uk Kim, Han-Oh Park, Chad L. Myers, Akhilesh Pandey, Daniel Durocher, Brenda J. Andrews, and Charles Boone
- You have accessSmall-scale copy number variation and large-scale changes in gene expressionYuriy Mileyko, Richard I. Joh, and Joshua S. Weitz
- Open AccessGenes involved in pre-mRNA 3′-end formation and transcription termination revealed by a lin-15 operon Muv suppressor screenMingxue Cui, Mary Ann Allen, Alison Larsen, Margaret MacMorris, Min Han, and Tom Blumenthal
Immunology
- You have accessHow the thymus designs antigen-specific and self-tolerant T cell receptor sequencesAndrej Košmrlj, Abhishek K. Jha, Eric S. Huseby, Mehran Kardar, and Arup K. Chakraborty
- You have accessFADD and caspase-8 control the outcome of autophagic signaling in proliferating T cellsBryan D. Bell, Sabrina Leverrier, Brian M. Weist, Ryan H. Newton, Adrian F. Arechiga, Keith A. Luhrs, Naomi S. Morrissette, and Craig M. Walsh
- You have accessAdjuvants targeting innate and adaptive immunity synergize to enhance tumor immunotherapyGrégory Verdeil, Kristi Marquardt, Charles D. Surh, and Linda A. Sherman
- Open AccessExploring regulatory mechanisms of CD8+ T cell contractionMartin Prlic and Michael J. Bevan
- You have accessFunctional recognition of a distinct receptor preferential for leukotriene E4 in mice lacking the cysteinyl leukotriene 1 and 2 receptorsAkiko Maekawa, Yoshihide Kanaoka, Wei Xing, and K. Frank Austen
Medical Sciences
- Open AccessIncreased substrate oxidation and mitochondrial uncoupling in skeletal muscle of endurance-trained individualsDouglas E. Befroy, Kitt Falk Petersen, Sylvie Dufour, Graeme F. Mason, Douglas L. Rothman, and Gerald I. Shulman
See companion article:
- In This Issue- Oct 28, 2008
- You have accessStriatal progenitors derived from human ES cells mature into DARPP32 neurons in vitro and in quinolinic acid-lesioned ratsLaetitia Aubry, Aurore Bugi, Nathalie Lefort, France Rousseau, Marc Peschanski, and Anselme L. Perrier
- You have accessThe ubiquitin ligase Siah2 regulates tumorigenesis and metastasis by HIF-dependent and -independent pathwaysJianfei Qi, Koh Nakayama, Supriya Gaitonde, James S. Goydos, Stan Krajewski, Alexey Eroshkin, Dafna Bar-Sagi, David Bowtell, and Ze'ev Ronai
- Open AccessHec1 overexpression hyperactivates the mitotic checkpoint and induces tumor formation in vivoElena Diaz-Rodríguez, Rocio Sotillo, Juan-Manuel Schvartzman, and Robert Benezra
Microbiology
- You have accessHIV rebounds from latently infected cells, rather than from continuing low-level replicationBeda Joos, Marek Fischer, Herbert Kuster, Satish K. Pillai, Joseph K. Wong, Jürg Böni, Bernard Hirschel, Rainer Weber, Alexandra Trkola, Huldrych F. Günthard, and The Swiss HIV Cohort Study2
- You have accessFaecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients
- From the Cover
Harry Sokol, Bénédicte Pigneur, Laurie Watterlot, Omar Lakhdari, Luis G. Bermúdez-Humarán, Jean-Jacques Gratadoux, Sébastien Blugeon, Chantal Bridonneau, Jean-Pierre Furet, Gérard Corthier, Corinne Grangette, Nadia Vasquez, Philippe Pochart, Germain Trugnan, Ginette Thomas, Hervé M. Blottière, Joël Doré, Philippe Marteau, Philippe Seksik, and Philippe LangellaSee companion article:
- In This Issue- Oct 28, 2008
- You have accessChromosome replication dynamics in the archaeon Sulfolobus acidocaldariusIain G. Duggin, Simon A. McCallum, and Stephen D. Bell
- You have accessRoles of RIG-I N-terminal tandem CARD and splice variant in TRIM25-mediated antiviral signal transductionMichaela U. Gack, Axel Kirchhofer, Young C. Shin, Kyung-Soo Inn, Chengyu Liang, Sheng Cui, Sua Myong, Taekjip Ha, Karl-Peter Hopfner, and Jae U. Jung
- Open AccessA host dicer is required for defective viral RNA production and recombinant virus vector RNA instability for a positive sense RNA virusXuemin Zhang and Donald L. Nuss
- You have accessInduction of group A Streptococcus virulence by a human antimicrobial peptideIoannis Gryllos, Hien J. Tran-Winkler, Ming-Fang Cheng, Hachung Chung, Robert Bolcome III, Wuyuan Lu, Robert I. Lehrer, and Michael R. Wessels
- You have accessThe potential of desferrioxamine-gallium as an anti-Pseudomonas therapeutic agentEhud Banin, Alina Lozinski, Keith M. Brady, Eduard Berenshtein, Phillip W. Butterfield, Maya Moshe, Mordechai Chevion, Everett Peter Greenberg, and Eyal Banin
See companion article:
- In This Issue- Oct 28, 2008
- Open AccessEffects of the gut microbiota on host adiposity are modulated by the short-chain fatty-acid binding G protein-coupled receptor, Gpr41Buck S. Samuel, Abdullah Shaito, Toshiyuki Motoike, Federico E. Rey, Fredrik Backhed, Jill K. Manchester, Robert E. Hammer, S. Clay Williams, Jan Crowley, Masashi Yanagisawa, and Jeffrey I. Gordon
Neuroscience
- You have accessActivation of P2X7 receptors in glial satellite cells reduces pain through downregulation of P2X3 receptors in nociceptive neuronsYong Chen, Xiaofei Zhang, Congying Wang, GuangWen Li, Yanping Gu, and Li-Yen Mae Huang
- You have accessVulnerability of white matter towards antenatal hypoxia is linked to a species-dependent regulation of glutamate receptor subunitsRomain H. Fontaine, Paul Olivier, Véronique Massonneau, Philippe Leroux, Vincent Degos, Sophie Lebon, Vincent El Ghouzzi, Vincent Lelièvre, Pierre Gressens, and Olivier Baud
- Open AccessProcedure for recording the simultaneous activity of single neurons distributed across cortical areas during sensory discriminationAdrián Hernández, Verónica Nácher, Rogelio Luna, Manuel Alvarez, Antonio Zainos, Silvia Cordero, Liliana Camarillo, Yuriria Vázquez, Luis Lemus, and Ranulfo Romo
- You have accessA specialized NMDA receptor function in layer 5 recurrent microcircuitry of the adult rat prefrontal cortexHuaixing Wang, George G. Stradtman III, Xiao-Jing Wang, and Wen-Jun Gao
- You have accessDelayed plasticity of inhibitory neurons in developing visual cortexSunil P. Gandhi, Yuchio Yanagawa, and Michael P. Stryker
- Open AccessSequential development of synapses in dendritic domains during adult neurogenesisWolfgang Kelsch, Chia-Wei Lin, and Carlos Lois
Pharmacology
- Open AccessIdentification of a new JNK inhibitor targeting the JNK-JIP interaction siteJohn L. Stebbins, Surya K. De, Thomas Machleidt, Barbara Becattini, Jesus Vazquez, Christian Kuntzen, Li-Hsing Chen, Jason F. Cellitti, Megan Riel-Mehan, Aras Emdadi, Giovanni Solinas, Michael Karin, and Maurizio Pellecchia
Plant Biology
- You have accessSubmergence tolerance conferred by Sub1A is mediated by SLR1 and SLRL1 restriction of gibberellin responses in riceTakeshi Fukao and Julia Bailey-Serres
Commentaries
See companion article:
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