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Research Article

Optical lock-in detection imaging microscopy for contrast-enhanced imaging in living cells

Gerard Marriott, Shu Mao, Tomoyo Sakata, Jing Ran, David K. Jackson, Chutima Petchprayoon, Timothy J. Gomez, Erica Warp, Orapim Tulyathan, Holly L. Aaron, Ehud Y. Isacoff, and Yuling Yan
PNAS November 18, 2008 105 (46) 17789-17794; https://doi.org/10.1073/pnas.0808882105
Gerard Marriott
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  • For correspondence: marriott@physiology.wisc.edu
Shu Mao
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Tomoyo Sakata
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Jing Ran
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David K. Jackson
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Chutima Petchprayoon
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Timothy J. Gomez
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Erica Warp
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Orapim Tulyathan
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Holly L. Aaron
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Ehud Y. Isacoff
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Yuling Yan
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  1. Communicated by James A. Spudich, Stanford University School of Medicine, Stanford, CA, September 10, 2008 (received for review July 28, 2008)

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Article Information

vol. 105 no. 46 17789-17794
DOI: 
https://doi.org/10.1073/pnas.0808882105
PubMed: 
19004775

Published By: 
National Academy of Sciences
Print ISSN: 
0027-8424
Online ISSN: 
1091-6490
History: 
  • Published in issue November 18, 2008.
  • Published first November 12, 2008.

Article Versions

  • Previous version (November 12, 2008 - 11:47).
  • You are viewing the most recent version of this article.
Copyright & Usage: 
© 2008 by The National Academy of Sciences of the USA

Author Information

  1. Gerard Marriotta,1,
  2. Shu Maoa,
  3. Tomoyo Sakataa,
  4. Jing Rana,
  5. David K. Jacksona,
  6. Chutima Petchprayoona,
  7. Timothy J. Gomezb,
  8. Erica Warpc,
  9. Orapim Tulyathanc,
  10. Holly L. Aarond,
  11. Ehud Y. Isacoffc,e, and
  12. Yuling Yanf,g
  1. Departments of aPhysiology and
  2. bAnatomy, University of Wisconsin, 1300 University Avenue, Madison, WI 53705;
  3. cDepartment of Molecular and Cell Biology and
  4. dMolecular Imaging Center, University of California, Berkeley, CA 94720;
  5. eMaterial Science Division and Physical Bioscience Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720;
  6. fSchool of Engineering, Santa Clara University, El Camino Real, Santa Clara, CA 95053; and
  7. gDepartment of Otolaryngology, Stanford University, Stanford, CA 94305
  1. Communicated by James A. Spudich, Stanford University School of Medicine, Stanford, CA, September 10, 2008 (received for review July 28, 2008)

Footnotes

  • 1To whom correspondence should be addressed. E-mail: marriott{at}physiology.wisc.edu
  • Author contributions: G.M., E.Y.I., and Y.Y. designed research; G.M., S.M., T.S., J.R., T.J.G., E.W., O.T., H.L.A., and Y.Y. performed research; G.M., S.M., T.S., J.R., D.K.J., C.P., E.Y.I., and Y.Y. contributed new reagents/analytic tools; G.M. and Y.Y. analyzed data; and G.M., E.Y.I., and Y.Y. wrote the paper.

  • Conflict of interest statement: Related probes to those detailed in this article have been patented by G.M. through the Wisconsin Alumni Research Foundation (WARF).

  • This article contains supporting information online at www.pnas.org/cgi/content/full/0808882105/DCSupplemental.

  • © 2008 by The National Academy of Sciences of the USA

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Article usage

Article usage: November 2008 to January 2021

AbstractFullPdf
Nov 20084057129565
Dec 200857962130
Total 20084636191695
Jan 20092962886
Feb 20092393363
Mar 20091785574
Apr 20091344658
May 2009873734
Jun 2009642733
Jul 2009683573
Aug 2009432933
Sep 2009442722
Oct 20091062742
Nov 2009831945
Dec 2009522526
Total 20091394388589
Jan 2010714364
Feb 2010553952
Mar 2010672646
Apr 2010874358
May 2010563229
Jun 2010522221
Jul 2010523735
Aug 2010462932
Sep 2010614341
Oct 2010543821
Nov 2010382924
Dec 2010473935
Total 2010686420458
Jan 2011462530
Feb 2011482537
Mar 2011352824
Apr 2011542127
May 2011562047
Jun 2011663238
Jul 2011472638
Aug 2011571929
Sep 2011752640
Oct 2011781623
Nov 2011552228
Dec 2011462019
Total 2011663280380
Jan 2012612721
Feb 2012642019
Mar 2012672835
Apr 2012401626
May 2012362021
Jun 2012761735
Jul 2012592936
Aug 2012391723
Sep 2012421932
Oct 201250333
Nov 201243629
Dec 2012431321
Total 2012620215331
Jan 2013472131
Feb 2013402626
Mar 2013661222
Apr 2013691932
May 201327614
Jun 2013431922
Jul 2013372119
Aug 2013321015
Sep 2013381627
Oct 2013611016
Nov 2013461016
Dec 2013451015
Total 2013551180255
Jan 2014401819
Feb 2014481920
Mar 201449618
Apr 2014543522
May 2014321421
Jun 201452821
Jul 2014281713
Aug 2014432614
Sep 2014592719
Oct 2014502132
Nov 2014251513
Dec 2014241116
Total 2014504217228
Jan 2015201113
Feb 201530149
Mar 2015471121
Apr 2015391723
May 2015372013
Jun 2015261327
Jul 201519510
Aug 2015341516
Sep 2015391739
Oct 2015581834
Nov 2015381114
Dec 2015221313
Total 2015409165232
Jan 2016601324
Feb 2016441413
Mar 2016321510
Apr 201630267
May 2016332014
Jun 2016291519
Jul 201624920
Aug 201621716
Sep 2016252011
Oct 2016312311
Nov 2016421414
Dec 2016261110
Total 2016397187169
Jan 2017251412
Feb 2017422518
Mar 2017373519
Apr 2017312321
May 2017411713
Jun 2017372526
Jul 2017221920
Aug 2017182614
Sep 2017262621
Oct 201718258
Nov 2017381915
Dec 201715136
Total 2017350267193
Jan 2018282011
Feb 2018332827
Mar 2018394125
Apr 201843379
May 201833249
Jun 201827327
Jul 201841418
Aug 2018353510
Sep 201822225
Oct 20183417
Nov 201843812
Dec 20184296
Total 2018312388136
Jan 2019121512
Feb 201941712
Mar 201953113
Apr 201962915
May 20197207
Jun 20193365
Jul 201942812
Aug 201965828
Sep 20193227
Oct 20194318
Nov 201963712
Dec 201943511
Total 201964359142
Jan 202033110
Feb 202022411
Mar 202072414
Apr 202032711
May 2020123521
Jun 202071027
Jul 20202188
Aug 20205159
Sep 202064717
Oct 20205244
Nov 202052611
Dec 202002411
Total 202057305154
Jan 202182510
Total 202182510
Total1065135873972
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Optical lock-in detection imaging microscopy for contrast-enhanced imaging in living cells
Gerard Marriott, Shu Mao, Tomoyo Sakata, Jing Ran, David K. Jackson, Chutima Petchprayoon, Timothy J. Gomez, Erica Warp, Orapim Tulyathan, Holly L. Aaron, Ehud Y. Isacoff, Yuling Yan
Proceedings of the National Academy of Sciences Nov 2008, 105 (46) 17789-17794; DOI: 10.1073/pnas.0808882105

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Optical lock-in detection imaging microscopy for contrast-enhanced imaging in living cells
Gerard Marriott, Shu Mao, Tomoyo Sakata, Jing Ran, David K. Jackson, Chutima Petchprayoon, Timothy J. Gomez, Erica Warp, Orapim Tulyathan, Holly L. Aaron, Ehud Y. Isacoff, Yuling Yan
Proceedings of the National Academy of Sciences Nov 2008, 105 (46) 17789-17794; DOI: 10.1073/pnas.0808882105
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