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Research Article

Emergent decision-making in biological signal transduction networks

Tomáš Helikar, John Konvalina, Jack Heidel, and Jim A. Rogers
PNAS February 12, 2008 105 (6) 1913-1918; first published February 4, 2008; https://doi.org/10.1073/pnas.0705088105
Tomáš Helikar
*Department of Pathology and Microbiology, University of Nebraska Medical Center, 983135 Nebraska Medical Center, Omaha, NE 68198; and
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John Konvalina
†Department of Mathematics, University of Nebraska, 6001 Dodge Street, Omaha, NE 68182
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Jack Heidel
†Department of Mathematics, University of Nebraska, 6001 Dodge Street, Omaha, NE 68182
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Jim A. Rogers
*Department of Pathology and Microbiology, University of Nebraska Medical Center, 983135 Nebraska Medical Center, Omaha, NE 68198; and
†Department of Mathematics, University of Nebraska, 6001 Dodge Street, Omaha, NE 68182
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  • For correspondence: jrogers@unmc.edu
  1. Edited by Eugene V. Koonin, National Institutes of Health, Bethesda, MD, and accepted by the Editorial Board December 14, 2007 (received for review May 30, 2007)

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Article Information

vol. 105 no. 6 1913-1918
DOI: 
https://doi.org/10.1073/pnas.0705088105
PubMed: 
18250321

Published By: 
National Academy of Sciences
Print ISSN: 
0027-8424
Online ISSN: 
1091-6490
History: 
  • Received May 30, 2007
  • Published in issue February 12, 2008.
  • Published first February 4, 2008.

Copyright & Usage: 
© 2008 by The National Academy of Sciences of the USA

Author Information

  1. Tomáš Helikar*,
  2. John Konvalina†,
  3. Jack Heidel†, and
  4. Jim A. Rogers*,†,‡
  1. *Department of Pathology and Microbiology, University of Nebraska Medical Center, 983135 Nebraska Medical Center, Omaha, NE 68198; and
  2. †Department of Mathematics, University of Nebraska, 6001 Dodge Street, Omaha, NE 68182
  1. Edited by Eugene V. Koonin, National Institutes of Health, Bethesda, MD, and accepted by the Editorial Board December 14, 2007 (received for review May 30, 2007)

Footnotes

  • ↵‡To whom correspondence should be addressed. E-mail: jrogers{at}unmc.edu
  • Author contributions: J.K., J.H., and J.A.R. designed research; T.H., J.K., and J.A.R. performed research; T.H., J.K., and J.A.R. contributed new reagents/analytic tools; T.H., J.K., and J.A.R. analyzed data; and J.A.R. wrote the paper.

  • The authors declare no conflict of interest.

  • This article is a PNAS Direct Submission. E.V.K. is a guest editor invited by the Editorial Board.

  • This article contains supporting information online at www.pnas.org/cgi/content/full/0705088105/DC1.

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Article usage

Article usage: February 2008 to January 2021

AbstractFullPdf
Feb 20081001314769
Mar 20081345593
Apr 20081397388
May 2008773657
Jun 2008613046
Jul 20081461640
Aug 20081111941
Sep 20081403265
Oct 20081194658
Nov 20081332047
Dec 2008881968
Total 200821496601372
Jan 20091491263
Feb 2009772625
Mar 20091092590
Apr 20091203174
May 20091072344
Jun 2009942141
Jul 2009772147
Aug 2009541317
Sep 2009681565
Oct 2009623246
Nov 2009634247
Dec 2009652239
Total 20091045283598
Jan 2010601424
Feb 2010871626
Mar 2010802727
Apr 2010611530
May 2010691322
Jun 201053817
Jul 2010402222
Aug 2010422415
Sep 2010402815
Oct 2010622240
Nov 2010562056
Dec 201027318
Total 2010677212312
Jan 2011361314
Feb 2011442019
Mar 2011361719
Apr 2011301520
May 2011522732
Jun 2011441425
Jul 2011331121
Aug 2011541920
Sep 2011552817
Oct 2011653925
Nov 2011572634
Dec 2011592824
Total 2011565257270
Jan 2012743238
Feb 2012593123
Mar 2012593128
Apr 2012512321
May 2012637320
Jun 2012706636
Jul 2012463113
Aug 2012371711
Sep 2012361516
Oct 2012381615
Nov 2012712654
Dec 2012453018
Total 2012649391293
Jan 2013672416
Feb 2013612221
Mar 2013452220
Apr 2013603120
May 2013512618
Jun 2013643016
Jul 2013333520
Aug 2013414917
Sep 2013411513
Oct 2013511528
Nov 2013501815
Dec 201358218
Total 2013622308212
Jan 2014692828
Feb 2014433612
Mar 2014442214
Apr 2014511215
May 2014371612
Jun 201429129
Jul 2014458712
Aug 2014478128
Sep 2014343433
Oct 2014422818
Nov 2014502516
Dec 2014744810
Total 2014565429207
Jan 2015592724
Feb 2015263114
Mar 2015663126
Apr 2015273511
May 2015251314
Jun 2015392814
Jul 2015311014
Aug 20153457
Sep 2015301812
Oct 2015309412
Nov 2015433015
Dec 2015353912
Total 2015445361175
Jan 2016302015
Feb 2016422010
Mar 2016764017
Apr 2016283114
May 2016692722
Jun 2016352316
Jul 201626104
Aug 2016431410
Sep 2016371711
Oct 2016401911
Nov 2016381511
Dec 2016372629
Total 2016501262170
Jan 2017451020
Feb 2017251113
Mar 2017402310
Apr 2017381720
May 201718710
Jun 2017292216
Jul 2017315014
Aug 2017263911
Sep 2017222813
Oct 2017322310
Nov 2017452323
Dec 201731119
Total 2017382264169
Jan 2018454114
Feb 2018875612
Mar 2018535013
Apr 2018726611
May 2018645712
Jun 201831367
Jul 2018565110
Aug 2018645710
Sep 2018464815
Oct 2018124414
Nov 20183534
Dec 201875316
Total 2018540612138
Jan 2019113518
Feb 201933511
Mar 201964314
Apr 2019105218
May 201993013
Jun 201943710
Jul 201932211
Aug 201992421
Sep 20192164
Oct 2019102610
Nov 201944110
Dec 201954914
Total 201976410154
Jan 2020105011
Feb 2020103123
Mar 2020102916
Apr 202023218
May 20208248
Jun 20207255
Jul 2020123315
Aug 20205288
Sep 202073711
Oct 2020145111
Nov 2020144822
Dec 20209447
Total 2020108432155
Jan 202163910
Total 202163910
Total833049204235
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Emergent decision-making in biological signal transduction networks
Tomáš Helikar, John Konvalina, Jack Heidel, Jim A. Rogers
Proceedings of the National Academy of Sciences Feb 2008, 105 (6) 1913-1918; DOI: 10.1073/pnas.0705088105

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Emergent decision-making in biological signal transduction networks
Tomáš Helikar, John Konvalina, Jack Heidel, Jim A. Rogers
Proceedings of the National Academy of Sciences Feb 2008, 105 (6) 1913-1918; DOI: 10.1073/pnas.0705088105
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Proceedings of the National Academy of Sciences: 105 (6)
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