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Research Article

Engineering of mucin-type human glycoproteins in yeast cells

Koh Amano, Yasunori Chiba, Yoshiko Kasahara, Yukinari Kato, Mika Kato Kaneko, Atsushi Kuno, Hiromi Ito, Kazuo Kobayashi, Jun Hirabayashi, Yoshifumi Jigami, and Hisashi Narimatsu
  1. *Research Center for Medical Glycoscience and
  2. §Research Institute for Cell Engineering, National Institute of Advanced Industrial Science and Technology, 1-1-1 Higashi, Tsukuba 305-8566, Japan; and
  3. ‡CMC R&D Laboratories, Kirin Pharma Co., Ltd., Hagiwara-cho, Takasaki 370-0013, Japan

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PNAS March 4, 2008 105 (9) 3232-3237; https://doi.org/10.1073/pnas.0710412105
Koh Amano
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Yasunori Chiba
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  • For correspondence: y-chiba@aist.go.jp jigami.yoshi@aist.go.jp
Yoshiko Kasahara
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Yukinari Kato
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Mika Kato Kaneko
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Atsushi Kuno
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Hiromi Ito
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Kazuo Kobayashi
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Jun Hirabayashi
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Yoshifumi Jigami
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  • For correspondence: y-chiba@aist.go.jp jigami.yoshi@aist.go.jp
Hisashi Narimatsu
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  1. Edited by Carolyn R. Bertozzi, University of California, Berkeley, CA, and approved January 7, 2008 (received for review November 1, 2007)

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Article Information

vol. 105 no. 9 3232-3237
DOI: 
https://doi.org/10.1073/pnas.0710412105
PubMed: 
18296643

Published By: 
National Academy of Sciences
Print ISSN: 
0027-8424
Online ISSN: 
1091-6490
History: 
  • Published in issue March 4, 2008.
  • Published first February 22, 2008.

Copyright & Usage: 
© 2008 by The National Academy of Sciences of the USA

Author Information

  1. Koh Amano *,
  2. Yasunori Chiba * , † ,
  3. Yoshiko Kasahara *,
  4. Yukinari Kato *,
  5. Mika Kato Kaneko *,
  6. Atsushi Kuno *,
  7. Hiromi Ito *,
  8. Kazuo Kobayashi ‡ ,
  9. Jun Hirabayashi *,
  10. Yoshifumi Jigami † , § , and
  11. Hisashi Narimatsu *
  1. *Research Center for Medical Glycoscience and
  2. §Research Institute for Cell Engineering, National Institute of Advanced Industrial Science and Technology, 1-1-1 Higashi, Tsukuba 305-8566, Japan; and
  3. ‡CMC R&D Laboratories, Kirin Pharma Co., Ltd., Hagiwara-cho, Takasaki 370-0013, Japan
  1. Edited by Carolyn R. Bertozzi, University of California, Berkeley, CA, and approved January 7, 2008 (received for review November 1, 2007)

Footnotes

  • †To whom correspondence may be addressed. E-mail: y-chiba{at}aist.go.jp or jigami.yoshi{at}aist.go.jp
  • Author contributions: Y.C., J.H., Y.J., and H.N. designed research; K.A., Y. Kasahara, Y. Kato, M.K.K., A.K., H.I., and K.K. performed research; K.A., Y. Kasahara, Y. Kato, and A.K. analyzed data; and K.A., Y.C., and Y. Kato wrote the paper.

  • The authors declare no conflict of interest.

  • This article is a PNAS Direct Submission.

  • This article contains supporting information online at www.pnas.org/cgi/content/full/0710412105/DC1.

  • © 2008 by The National Academy of Sciences of the USA

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Feb 20081220138
Mar 2008498200366
Apr 200810997119
May 2008528880
Jun 2008617978
Jul 20081931938
Aug 20081721539
Sep 20082122259
Oct 20081532278
Nov 20081041827
Dec 2008772825
Total 200817535881047
Jan 2009852225
Feb 2009782220
Mar 2009724332
Apr 20096415121
May 20095517115
Jun 20094926114
Jul 2009523541
Aug 2009451520
Sep 2009881735
Oct 2009732443
Nov 2009471723
Dec 2009631819
Total 2009771271608
Jan 2010511218
Feb 2010601735
Mar 2010481114
Apr 2010432620
May 2010662716
Jun 2010592310
Jul 2010572012
Aug 20101072323
Sep 2010321611
Oct 2010365138
Nov 2010423314
Dec 2010221210
Total 2010623271221
Jan 201133219
Feb 2011271714
Mar 2011241915
Apr 201127219
May 2011242911
Jun 2011281513
Jul 2011351316
Aug 201141811
Sep 2011501515
Oct 2011533615
Nov 2011482521
Dec 2011303310
Total 2011420252159
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Feb 201272148
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Apr 2012431011
May 201235188
Jun 2012291810
Jul 201225129
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Sep 201246911
Oct 201236817
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Dec 2012251918
Total 2012510185129
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Feb 201348168
Mar 2013501213
Apr 201335188
May 201336178
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Jul 201327139
Aug 20131046
Sep 20132965
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Total 201343114794
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Total 201433518572
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Feb 201538167
Mar 201525115
Apr 201534144
May 20153466
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Jul 20152194
Aug 201527128
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Total 201533511676
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Feb 20162314
Mar 20163136
Apr 2016211212
May 201619150
Jun 20161067
Jul 20161945
Aug 201620149
Sep 20163253
Oct 201622193
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Total 20162809669
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Feb 2017771
Mar 201716113
Apr 20171132
May 20171061
Jun 20171584
Jul 20171565
Aug 201712105
Sep 20171785
Oct 201719145
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Total 20171689443
Jan 20183226
Feb 201816195
Mar 201810146
Apr 201833348
May 201825278
Jun 20181594
Jul 201819228
Aug 201819213
Sep 201816115
Oct 20186236
Nov 20186227
Dec 20183254
Total 201820022970
Jan 201962010
Feb 20193144
Mar 201911410
Apr 201941912
May 201961199
Jun 20194226
Jul 20191178
Aug 20196175
Sep 20199168
Oct 201992711
Nov 201912611
Dec 201912611
Total 201951337105
Jan 20203236
Feb 20203129
Mar 202011510
Apr 202043217
May 202062313
Jun 20201152
Jul 20203217
Aug 20200129
Sep 20200175
Oct 202012915
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Total 202031277114
Jan 202114214
Feb 202142211
Mar 2021010
Total 202156525
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Engineering of mucin-type human glycoproteins in yeast cells
Koh Amano, Yasunori Chiba, Yoshiko Kasahara, Yukinari Kato, Mika Kato Kaneko, Atsushi Kuno, Hiromi Ito, Kazuo Kobayashi, Jun Hirabayashi, Yoshifumi Jigami, Hisashi Narimatsu
Proceedings of the National Academy of Sciences Mar 2008, 105 (9) 3232-3237; DOI: 10.1073/pnas.0710412105

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Engineering of mucin-type human glycoproteins in yeast cells
Koh Amano, Yasunori Chiba, Yoshiko Kasahara, Yukinari Kato, Mika Kato Kaneko, Atsushi Kuno, Hiromi Ito, Kazuo Kobayashi, Jun Hirabayashi, Yoshifumi Jigami, Hisashi Narimatsu
Proceedings of the National Academy of Sciences Mar 2008, 105 (9) 3232-3237; DOI: 10.1073/pnas.0710412105
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