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Table of Contents
January 06, 2009; vol. 106 no. 1
This Week in PNAS
Letters (Online Only)
- You have accessVitamin B deficiency causes neural cell loss and cognitive impairment in the developing ratJean-Luc Daval, Sébastien Blaise, and Jean-Louis Guéant
See companion article:
- You have accessReply to Daval et al.: How comparable are brain changes induced by dietary methyl-donor deficiency occurring before birth or after weaning?Aron M. Troen and Irwin H. Rosenberg
See companion article:
- You have accessCoastal eutrophication: Whether N and/or P should be abated depends on the dynamic mass balanceAndreas C. Bryhn and Lars Håkanson
See companion article:
- You have accessReply to Bryhn and Håkanson: Models for the Baltic agree with our experiments and observations in lakesD. W. Schindler and R. E. Hecky
See companion article:
Editorial
Physical Sciences
Applied Mathematics
- You have accessForce generation by a dynamic Z-ring in Escherichia coli cell divisionJun F. Allard and Eric N. Cytrynbaum
Applied Physical Sciences
- You have accessThe key role of the surface membrane in why gastropod nacre grows in towersAntonio G. Checa, Julyan H. E. Cartwright, and Marc-Georg Willinger
- You have accessIdentification of direct residue contacts in protein–protein interaction by message passingMartin Weigt, Robert A. White, Hendrik Szurmant, James A. Hoch, and Terence Hwa
Chemistry
- You have accessImaging the glycome
- Inaugural Article
Scott T. Laughlin and Carolyn R. BertozziSee companion article:
- Profile of Carolyn Bertozzi- Feb 16, 2010
- Open AccessGlyconanoparticles allow pre-symptomatic in vivo imaging of brain diseaseSander I. van Kasteren, Sandra J. Campbell, Sébastien Serres, Daniel C. Anthony, Nicola R. Sibson, and Benjamin G. Davis
See companion article:
- In This Issue- Jan 06, 2009
- You have accessFolding energy landscape and network dynamics of small globular proteinsNaoto Hori, George Chikenji, R. Stephen Berry, and Shoji Takada
Engineering
- You have accessDirected self-organization of single DNA molecules in a nanoslit via embedded nanopit arrays
- From the Cover
Walter Reisner, Niels B. Larsen, Henrik Flyvbjerg, Jonas O. Tegenfeldt, and Anders Kristensen
Geology
- Open AccessTwo-phase increase in the maximum size of life over 3.5 billion years reflects biological innovation and environmental opportunityJonathan L. Payne, Alison G. Boyer, James H. Brown, Seth Finnegan, Michał Kowalewski, Richard A. Krause Jr., S. Kathleen Lyons, Craig R. McClain, Daniel W. McShea, Philip M. Novack-Gottshall, Felisa A. Smith, Jennifer A. Stempien, and Steve C. Wang
Geophysics
- You have accessNonlinear threshold behavior during the loss of Arctic sea iceI. Eisenman and J. S. Wettlaufer
Social Sciences
Anthropology
- You have accessCulture, population structure, and low genetic diversity in Pleistocene homininsL. S. Premo and Jean-Jacques Hublin
Psychology
- Open AccessAn empirical explanation of aperture effects
- From the Cover
Kyongje Sung, William T. Wojtach, and Dale Purves
Biological Sciences
Anthropology
- You have accessCulture, population structure, and low genetic diversity in Pleistocene homininsL. S. Premo and Jean-Jacques Hublin
Applied Biological Sciences
- You have accessThe key role of the surface membrane in why gastropod nacre grows in towersAntonio G. Checa, Julyan H. E. Cartwright, and Marc-Georg Willinger
- You have accessCombined targeting of lentiviral vectors and positioning of transduced cells by magnetic nanoparticlesAndreas Hofmann, Daniela Wenzel, Ulrich M. Becher, Daniel F. Freitag, Alexandra M. Klein, Dietmar Eberbeck, Maike Schulte, Katrin Zimmermann, Christian Bergemann, Bernhard Gleich, Wilhelm Roell, Thomas Weyh, Lutz Trahms, Georg Nickenig, Bernd K. Fleischmann, and Alexander Pfeifer
Biochemistry
- You have accessSlow peptide bond formation by proline and other N-alkylamino acids in translationMichael Y. Pavlov, Richard E. Watts, Zhongping Tan, Virginia W. Cornish, Måns Ehrenberg, and Anthony C. Forster
- You have accessWnt signaling targets ETO coactivation domain of TAF4/TFIID in vivoKevin J. Wright and Robert Tjian
See companion article:
- TAF4 takes flight- Jan 27, 2009
- You have accessPKCη regulates occludin phosphorylation and epithelial tight junction integrityTakuya Suzuki, Bertha C. Elias, Ankur Seth, Le Shen, Jerrold R. Turner, Francesco Giorgianni, Dominic Desiderio, Ramareddy Guntaka, and Radhakrishna Rao
Biophysics
- You have accessIdentification of direct residue contacts in protein–protein interaction by message passingMartin Weigt, Robert A. White, Hendrik Szurmant, James A. Hoch, and Terence Hwa
- You have accessFolding energy landscape and network dynamics of small globular proteinsNaoto Hori, George Chikenji, R. Stephen Berry, and Shoji Takada
- You have accessDirected self-organization of single DNA molecules in a nanoslit via embedded nanopit arrays
- From the Cover
Walter Reisner, Niels B. Larsen, Henrik Flyvbjerg, Jonas O. Tegenfeldt, and Anders Kristensen - You have accessTransmission of allostery through the lectin domain in selectin-mediated cell adhesionTravis T. Waldron and Timothy A. Springer
- You have accessAccurate SHAPE-directed RNA structure determinationKatherine E. Deigan, Tian W. Li, David H. Mathews, and Kevin M. Weeks
- You have accessDynamics of one-state downhill protein foldingPeng Li, Fabiana Y. Oliva, Athi N. Naganathan, and Victor Muñoz
- You have accessResolving cadherin interactions and binding cooperativity at the single-molecule levelYunxiang Zhang, Sanjeevi Sivasankar, W. James Nelson, and Steven Chu
- You have accessUnliganded gating of acetylcholine receptor channelsPrasad Purohit and Anthony Auerbach
- You have accessCondensation of FtsZ filaments can drive bacterial cell divisionGanhui Lan, Brian R. Daniels, Terrence M. Dobrowsky, Denis Wirtz, and Sean X. Sun
- Open AccessMapping RNA exit channel on transcribing RNA polymerase II by FRET analysisChin-Yu Chen, Chia-Chi Chang, Chi-Fu Yen, Michael T.-K. Chiu, and Wei-Hau Chang
- You have accessFilament rigidity causes F-actin depletion from nonbinding surfacesCharles I. Fisher and Scot C. Kuo
- Open AccessA conserved protonation-dependent switch controls drug binding in the Abl kinaseYibing Shan, Markus A. Seeliger, Michael P. Eastwood, Filipp Frank, Huafeng Xu, Morten Ø Jensen, Ron O. Dror, John Kuriyan, and David E. Shaw
Cell Biology
- You have accessImaging the glycome
- Inaugural Article
Scott T. Laughlin and Carolyn R. BertozziSee companion article:
- Profile of Carolyn Bertozzi- Feb 16, 2010
- You have accessForce generation by a dynamic Z-ring in Escherichia coli cell divisionJun F. Allard and Eric N. Cytrynbaum
- You have accessDisruption of the SRC-1 gene in mice suppresses breast cancer metastasis without affecting primary tumor formationShu Wang, Yuhui Yuan, Lan Liao, Shao-Qing Kuang, Jean Ching-Yi Tien, Bert W. O'Malley, and Jianming Xu
- You have accessReprogramming of murine and human somatic cells using a single polycistronic vectorBryce W. Carey, Styliani Markoulaki, Jacob Hanna, Kris Saha, Qing Gao, Maisam Mitalipova, and Rudolf Jaenisch
- You have accessA role for the host coatomer and KDEL receptor in early vaccinia biogenesisLeiliang Zhang, Stella Y. Lee, Galina V. Beznoussenko, Peter J. Peters, Jia-Shu Yang, Hui-ya Gilbert, Abraham L. Brass, Stephen J. Elledge, Stuart N. Isaacs, Bernard Moss, Alexander Mironov, and Victor W. Hsu
- You have accessContinuous elimination of oxidized nucleotides is necessary to prevent rapid onset of cellular senescencePriyamvada Rai, Tamer T. Onder, Jennifer J. Young, Jose L. McFaline, Bo Pang, Peter C. Dedon, and Robert A. Weinberg
Developmental Biology
- You have accessTwo-step oligoclonal development of male germ cellsHiroo Ueno, Brit B. Turnbull, and Irving L. Weissman
- You have accessEssential functions of the Williams-Beuren syndrome-associated TFII-I genes in embryonic developmentBadam Enkhmandakh, Aleksandr V. Makeyev, Lkhamsuren Erdenechimeg, Frank H. Ruddle, Nyam-Osor Chimge, Maria Isabel Tussie-Luna, Ananda L. Roy, and Dashzeveg Bayarsaihan
Ecology
- You have accessSimple prediction of interaction strengths in complex food websEric L. Berlow, Jennifer A. Dunne, Neo D. Martinez, Philip B. Stark, Richard J. Williams, and Ulrich Brose
- You have accessGreat ranging associated with greater reproductive investment in mammalsHerman Pontzer and Jason M. Kamilar
- Open AccessTrophic cascades promote threshold-like shifts in pelagic marine ecosystemsMichele Casini, Joakim Hjelm, Juan-Carlos Molinero, Johan Lövgren, Massimiliano Cardinale, Valerio Bartolino, Andrea Belgrano, and Georgs Kornilovs
Environmental Sciences
Evolution
- Open AccessTwo-phase increase in the maximum size of life over 3.5 billion years reflects biological innovation and environmental opportunityJonathan L. Payne, Alison G. Boyer, James H. Brown, Seth Finnegan, Michał Kowalewski, Richard A. Krause Jr., S. Kathleen Lyons, Craig R. McClain, Daniel W. McShea, Philip M. Novack-Gottshall, Felisa A. Smith, Jennifer A. Stempien, and Steve C. Wang
- You have accessPopulation genetics of Trypanosoma brucei gambiense, the agent of sleeping sickness in Western AfricaMathurin Koffi, Thierry De Meeûs, Bruno Bucheton, Philippe Solano, Mamadou Camara, Dramane Kaba, Gérard Cuny, Francisco J. Ayala, and Vincent Jamonneau
- You have accessGenome rhetoric and the emergence of compositional biasKalin Vetsigian and Nigel Goldenfeld
- You have accessContrasted patterns of hyperdiversification in Mediterranean hotspotsHervé Sauquet, Peter H. Weston, Cajsa Lisa Anderson, Nigel P. Barker, David J. Cantrill, Austin R. Mast, and Vincent Savolainen
Genetics
- You have accessWhole-genome association study identifies STK39 as a hypertension susceptibility gene
- From the Cover
Ying Wang, Jeffrey R. O'Connell, Patrick F. McArdle, James B. Wade, Sarah E. Dorff, Sanjiv J. Shah, Xiaolian Shi, Lin Pan, Evadnie Rampersaud, Haiqing Shen, James D. Kim, Arohan R. Subramanya, Nanette I. Steinle, Afshin Parsa, Carole C. Ober, Paul A. Welling, Aravinda Chakravarti, Alan B. Weder, Richard S. Cooper, Braxton D. Mitchell, Alan R. Shuldiner, and Yen-Pei C. ChangSee companion article:
- In This Issue- Jan 06, 2009
- You have accessSic1-induced DNA rereplication during meiosisKara E. Sawarynski, Nicole A. Najor, Andrea C. Kepsel, and George S. Brush
- Open AccessA regulatory interplay between miR-27a and Runx1 during megakaryopoiesisOren Ben-Ami, Niv Pencovich, Joseph Lotem, Ditsa Levanon, and Yoram Groner
- Open AccessChIP-on-chip significance analysis reveals large-scale binding and regulation by human transcription factor oncogenesAdam A. Margolin, Teresa Palomero, Pavel Sumazin, Andrea Califano, Adolfo A. Ferrando, and Gustavo Stolovitzky
Medical Sciences
- You have accessTargeting Nrf2 with the triterpenoid CDDO- imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice
- From the Cover
Thomas E. Sussan, Tirumalai Rangasamy, David J. Blake, Deepti Malhotra, Hazim El-Haddad, Djahida Bedja, Melinda S. Yates, Ponvijay Kombairaju, Masayuki Yamamoto, Karen T. Liby, Michael B. Sporn, Kathleen L. Gabrielson, Hunter C. Champion, Rubin M. Tuder, Thomas W. Kensler, and Shyam BiswalSee companion article:
- In This Issue- Jan 06, 2009
- You have accessEfficient colonic mucosal wound repair requires Trem2 signalingHiroshi Seno, Hiroyuki Miyoshi, Sarah L. Brown, Michael J. Geske, Marco Colonna, and Thaddeus S. Stappenbeck
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- In This Issue- Jan 06, 2009
- You have accessScaffold-based discovery of indeglitazar, a PPAR pan-active anti-diabetic agentDean R. Artis, Jack J. Lin, Chao Zhang, Weiru Wang, Upasana Mehra, Mylene Perreault, David Erbe, Heike I. Krupka, Bruce P. England, James Arnold, Alexander N. Plotnikov, Adhirai Marimuthu, Hoa Nguyen, Sarah Will, Maxime Signaevsky, John Kral, John Cantwell, Calvin Settachatgull, Douglas S. Yan, Daniel Fong, Angela Oh, Shenghua Shi, Patrick Womack, Benjamin Powell, Gaston Habets, Brian L. West, Kam Y. J. Zhang, Michael V. Milburn, George P. Vlasuk, K. Peter Hirth, Keith Nolop, Gideon Bollag, Prabha N. Ibrahim, and James F. Tobin
- You have accessThe role of PTEN/Akt/PI3K signaling in the maintenance and viability of prostate cancer stem-like cell populationsAnna Dubrovska, Sungeun Kim, Richard J. Salamone, John R. Walker, Sauveur-Michel Maira, Carlos García-Echeverría, Peter G. Schultz, and Venkateshwar A. Reddy
- You have accessActivated protein C ligation of ApoER2 (LRP8) causes Dab1-dependent signaling in U937 cellsXia V. Yang, Yajnavalka Banerjee, José A. Fernández, Hiroshi Deguchi, Xiao Xu, Laurent O. Mosnier, Rolf. T. Urbanus, Phillip G. de Groot, Tara C. White-Adams, Owen J. T. McCarty, and John H. Griffin
Microbiology
- You have accessStructurally diverse natural products that cause potassium leakage trigger multicellularity in Bacillus subtilisDaniel López, Michael A. Fischbach, Frances Chu, Richard Losick, and Roberto Kolter
- You have accessChanges in H5N1 influenza virus hemagglutinin receptor binding domain affect systemic spreadHui-Ling Yen, Jerry R. Aldridge, Adrianus C. M. Boon, Natalia A. Ilyushina, Rachelle Salomon, Diane J. Hulse-Post, Henju Marjuki, John Franks, David A. Boltz, Dorothy Bush, Aleksandr S. Lipatov, Richard J. Webby, Jerold E. Rehg, and Robert G. Webster
- You have accessTransformation and isolation of allelic exchange mutants of Chlamydia psittaci using recombinant DNA introduced by electroporationRachel Binet and Anthony T. Maurelli
Neuroscience
- Open AccessAn empirical explanation of aperture effects
- From the Cover
Kyongje Sung, William T. Wojtach, and Dale Purves - You have accessDe novo generation of a transmissible spongiform encephalopathy by mouse transgenesisChristina J. Sigurdson, K. Peter R. Nilsson, Simone Hornemann, Mathias Heikenwalder, Giuseppe Manco, Petra Schwarz, David Ott, Thomas Rülicke, Pawel P. Liberski, Christian Julius, Jeppe Falsig, Lothar Stitz, Kurt Wüthrich, and Adriano Aguzzi
See companion article:
- Constraining the loop, releasing prion infectivity- Dec 31, 2008
- In This Issue- Jan 06, 2009
- Open AccessThe Drosophila cell adhesion molecule Klingon is required for long-term memory formation and is regulated by NotchMotomi Matsuno, Junjiro Horiuchi, Tim Tully, and Minoru Saitoe
- You have accessSynaptic activity-responsive element in the Arc/Arg3.1 promoter essential for synapse-to-nucleus signaling in activated neuronsTakashi Kawashima, Hiroyuki Okuno, Mio Nonaka, Aki Adachi-Morishima, Nan Kyo, Michiko Okamura, Sayaka Takemoto-Kimura, Paul F. Worley, and Haruhiko Bito
- You have accessLocalizing interference during naming: Convergent neuroimaging and neuropsychological evidence for the function of Broca's areaTatiana T. Schnur, Myrna F. Schwartz, Daniel Y. Kimberg, Elizabeth Hirshorn, H. Branch Coslett, and Sharon L. Thompson-Schill
- Open AccessDividing glial cells maintain differentiated properties including complex morphology and functional synapsesWoo-Ping Ge, Wei Zhou, Qingming Luo, Lily Yeh Jan, and Yuh Nung Jan
Physiology
- Open AccessGlyconanoparticles allow pre-symptomatic in vivo imaging of brain diseaseSander I. van Kasteren, Sandra J. Campbell, Sébastien Serres, Daniel C. Anthony, Nicola R. Sibson, and Benjamin G. Davis
See companion article:
- In This Issue- Jan 06, 2009
Plant Biology
- You have accessIncremental steps toward incompatibility revealed by Arabidopsis epistatic interactions modulating salicylic acid pathway activationRubén Alcázar, Ana V. García, Jane E. Parker, and Matthieu Reymond
Psychology
- You have accessThe absence of reward induces inequity aversion in dogs
- From the Cover
Friederike Range, Lisa Horn, Zsófia Viranyi, and Ludwig Huber
Commentaries
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