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Research Article

Bimodal protein solubility distribution revealed by an aggregation analysis of the entire ensemble of Escherichia coli proteins

Tatsuya Niwa, Bei-Wen Ying, Katsuyo Saito, WenZhen Jin, Shoji Takada, Takuya Ueda, and Hideki Taguchi
PNAS March 17, 2009 106 (11) 4201-4206; https://doi.org/10.1073/pnas.0811922106
Tatsuya Niwa
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Bei-Wen Ying
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Katsuyo Saito
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WenZhen Jin
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Shoji Takada
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Takuya Ueda
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  • For correspondence: taguchi@k.u-tokyo.ac.jp ueda@k.u-tokyo.ac.jp
Hideki Taguchi
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  • For correspondence: taguchi@k.u-tokyo.ac.jp ueda@k.u-tokyo.ac.jp
  1. Edited by George H. Lorimer, University of Maryland, College Park, MD, and approved January 26, 2009 (received for review November 23, 2008)

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Article Information

vol. 106 no. 11 4201-4206
DOI: 
https://doi.org/10.1073/pnas.0811922106
PubMed: 
19251648

Published By: 
National Academy of Sciences
Print ISSN: 
0027-8424
Online ISSN: 
1091-6490
History: 
  • Published in issue March 17, 2009.
  • Published first February 27, 2009.

Copyright & Usage: 
© 2009

Author Information

  1. Tatsuya Niwaa,
  2. Bei-Wen Yinga,b,
  3. Katsuyo Saitoa,
  4. WenZhen Jinc,
  5. Shoji Takadac,
  6. Takuya Uedaa,1 and
  7. Hideki Taguchia,1
  1. aDepartment of Medical Genome Sciences, Graduate School of Frontier Sciences, University of Tokyo, Kashiwa, Chiba 277-8562, Japan;
  2. bDepartment of Bioinformatic Engineering, Graduate School of Information Science and Technology, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan; and
  3. cDepartment of Biophysics, Graduate School of Science, Kyoto University, Sakyo, Kyoto 606-8502, Japan
  1. Edited by George H. Lorimer, University of Maryland, College Park, MD, and approved January 26, 2009 (received for review November 23, 2008)

Footnotes

  • 1To whom correspondence may be addressed at:
    University of Tokyo, Bioscience Building 401, Kashiwanoha 5-1-5, Kashiwa 277-8562, Japan.
    E-mail: taguchi{at}k.u-tokyo.ac.jp or ueda{at}k.u-tokyo.ac.jp
  • Author contributions: T.N., B.-W.Y., T.U., and H.T. designed research; T.N., B.-W.Y., and K.S. performed research; T.N. and H.T. contributed new reagents/analytic tools; T.N., B.-W.Y., W.J., S.T., T.U., and H.T. analyzed data; and T.N., S.T., T.U., and H.T. wrote the paper.

  • The authors declare no conflict of interest.

  • This article is a PNAS Direct Submission.

  • This article contains supporting information online at www.pnas.org/cgi/content/full/0811922106/DCSupplemental.

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Article usage

Article usage: February 2009 to February 2021

AbstractFullPdf
Feb 2009458038
Mar 20094349144660
Apr 200956098112
May 200923181143
Jun 20091429373
Jul 20091327656
Aug 20091162922
Sep 20091083732
Oct 20091185347
Nov 2009767047
Dec 20091244345
Total 200964147241275
Jan 20101058251
Feb 2010642737
Mar 2010795234
Apr 2010635434
May 2010487324
Jun 2010515229
Jul 2010474638
Aug 2010603424
Sep 2010402828
Oct 2010304620
Nov 2010382517
Dec 2010442727
Total 2010669546363
Jan 2011282326
Feb 2011444340
Mar 2011363624
Apr 2011304219
May 2011343422
Jun 2011382836
Jul 2011472724
Aug 2011503327
Sep 2011522922
Oct 2011555444
Nov 2011534726
Dec 2011593629
Total 2011526432339
Jan 2012565638
Feb 2012645727
Mar 2012666435
Apr 2012434627
May 2012816239
Jun 2012635851
Jul 2012495044
Aug 2012484242
Sep 20123748482
Oct 2012303635
Nov 2012463026
Dec 2012333024
Total 2012616579870
Jan 2013363618
Feb 2013454833
Mar 2013453428
Apr 2013616845
May 2013435354
Jun 2013386348
Jul 2013404757
Aug 2013694563
Sep 2013176347
Oct 2013344925
Nov 2013516887
Dec 20133365102
Total 2013512639607
Jan 2014353027
Feb 2014694527
Mar 2014576840
Apr 201435108112
May 2014287873
Jun 20145410470
Jul 20144724682
Aug 20145024545
Sep 20143419125
Oct 20144943739
Nov 20143369933
Dec 20143637170
Total 20145272622643
Jan 20153835142
Feb 20154127734
Mar 20154222030
Apr 20154022931
May 20152110714
Jun 2015316828
Jul 20153213745
Aug 201545850583
Sep 20154713381
Oct 20154011442
Nov 20152311441
Dec 20153311627
Total 20154332716998
Jan 2016428819
Feb 2016238120
Mar 2016206216
Apr 2016435922
May 2016387739
Jun 2016406622
Jul 2016256121
Aug 2016415217
Sep 2016483913
Oct 2016484726
Nov 2016503832
Dec 2016333239
Total 2016451702286
Jan 2017296632
Feb 2017414720
Mar 201729538
Apr 2017304813
May 2017354523
Jun 2017385638
Jul 2017216222
Aug 2017494928
Sep 2017325413
Oct 2017433910
Nov 2017295414
Dec 201715305
Total 2017391603226
Jan 2018453819
Feb 2018647918
Mar 2018427518
Apr 20185611722
May 2018637914
Jun 2018486116
Jul 2018425212
Aug 2018496825
Sep 2018415410
Oct 2018137123
Nov 2018117313
Dec 20182559
Total 2018476822199
Jan 201976712
Feb 201977114
Mar 2019107922
Apr 201966118
May 2019125816
Jun 201989325
Jul 201928629
Aug 2019510115
Sep 2019615017
Oct 2019616725
Nov 20191216525
Dec 2019817813
Total 2019891276231
Jan 2020217225
Feb 202069829
Mar 202099421
Apr 20201612434
May 20201112643
Jun 202078742
Jul 202098524
Aug 2020147228
Sep 2020127622
Oct 20201914257
Nov 2020149333
Dec 20201911141
Total 20201571180399
Jan 20211217553
Feb 202148435
Total 20211625988
Total11277131006524
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Bimodal protein solubility distribution revealed by an aggregation analysis of the entire ensemble of Escherichia coli proteins
Tatsuya Niwa, Bei-Wen Ying, Katsuyo Saito, WenZhen Jin, Shoji Takada, Takuya Ueda, Hideki Taguchi
Proceedings of the National Academy of Sciences Mar 2009, 106 (11) 4201-4206; DOI: 10.1073/pnas.0811922106

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Bimodal protein solubility distribution revealed by an aggregation analysis of the entire ensemble of Escherichia coli proteins
Tatsuya Niwa, Bei-Wen Ying, Katsuyo Saito, WenZhen Jin, Shoji Takada, Takuya Ueda, Hideki Taguchi
Proceedings of the National Academy of Sciences Mar 2009, 106 (11) 4201-4206; DOI: 10.1073/pnas.0811922106
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