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Table of Contents
May 05, 2009; vol. 106 no. 18
This Week in PNAS
Letters (Online Only)
- You have accessBiodiversity and ecosystem functioning: Effects of the loss of salamander species richnessLars Gamfeldt
See companion article:
- Reply to Gamfeldt: Biodiversity and ecosystem functioning- Apr 27, 2009
- You have accessReply to Gamfeldt: Biodiversity and ecosystem functioningSean M. Rovito, Gabriela Parra-Olea, Carlos R. Vásquez-Almazán, Theodore Papenfuss, and David Wake
See companion article:
Physical Sciences
Applied Mathematics
- You have accessNewcomer insulin secretory granules as a highly calcium-sensitive poolMorten Gram Pedersen and Arthur Sherman
Applied Physical Sciences
- You have accessRemarkable resilience of teethHerzl Chai, James J.-W. Lee, Paul J. Constantino, Peter W. Lucas, and Brian R. Lawn
- You have accessBursting of sensitive polymersomes induced by curlingElyes Mabrouk, Damien Cuvelier, Françoise Brochard-Wyart, Pierre Nassoy, and Min-Hui Li
- You have accessSuperconducting characteristics of 4-Å carbon nanotube–zeolite composite
- From the Cover
Rolf Lortz, Qiucen Zhang, Wu Shi, Jian Ting Ye, Chunyin Qiu, Zhe Wang, Hongtao He, Ping Sheng, Tiezheng Qian, Zikang Tang, Ning Wang, Xixiang Zhang, Jiannong Wang, and Che Ting Chan - You have accessPhonon softening and crystallographic orientation of strained graphene studied by Raman spectroscopyMingyuan Huang, Hugen Yan, Changyao Chen, Daohua Song, Tony F. Heinz, and James Hone
Chemistry
- Open AccessFlexible electrical recording from cells using nanowire transistor arraysTzahi Cohen-Karni, Brian P. Timko, Lucien E. Weiss, and Charles M. Lieber
- You have accessDesorption electrospray ionization mass spectrometry reveals surface-mediated antifungal chemical defense of a tropical seaweed
- From the Cover
Amy L. Lane, Leonard Nyadong, Asiri S. Galhena, Tonya L. Shearer, E. Paige Stout, R. Mitchell Parry, Mark Kwasnik, May D. Wang, Mark E. Hay, Facundo M. Fernandez, and Julia KubanekSee companion article:
- In This Issue- May 05, 2009
- You have accessRole of a distal pocket in the catalytic O2 reduction by cytochrome c oxidase models immobilized on interdigitated array electrodesJames P. Collman, Richard A. Decréau, Hengwei Lin, Ali Hosseini, Ying Yang, Abhishek Dey, and Todd A. Eberspacher
Environmental Sciences
- You have accessSpatial and seasonal patterns in climate change, temperatures, and precipitation across the United StatesRobert W. Portmann, Susan Solomon, and Gabriele C. Hegerl
Physics
- Open AccessFermi surface nesting induced strong pairing in iron-based superconductorsK. Terashima, Y. Sekiba, J. H. Bowen, K. Nakayama, T. Kawahara, T. Sato, P. Richard, Y.-M. Xu, L. J. Li, G. H. Cao, Z.-A. Xu, H. Ding, and T. Takahashi
Statistics
- Open AccessStatistical estimation of cell-cycle progression and lineage commitment in Plasmodium falciparum reveals a homogeneous pattern of transcription in ex vivo cultureJacob E. Lemieux, Natalia Gomez-Escobar, Avi Feller, Celine Carret, Alfred Amambua-Ngwa, Robert Pinches, Felix Day, Sue A. Kyes, David J. Conway, Chris C. Holmes, and Chris I. Newbold
Sustainability Science
- You have accessSustainable water deliveries from the Colorado River in a changing climate
- From the Cover
Tim P. Barnett and David W. Pierce
Social Sciences
Anthropology
- Open AccessPolitical complexity predicts the spread of ethnolinguistic groupsThomas E. Currie and Ruth Mace
Psychology
- Open AccessSpatial ensemble statistics are efficient codes that can be represented with reduced attentionGeorge A. Alvarez and Aude Oliva
- You have accessFlexible neural mechanisms of cognitive control within human prefrontal cortexTodd S. Braver, Jessica L. Paxton, Hannah S. Locke, and Deanna M. Barch
Sustainability Science
- You have accessMangroves protected villages and reduced death toll during Indian super cycloneSaudamini Das and Jeffrey R. Vincent
Biological Sciences
Anthropology
- You have accessAncient Egyptian herbal wines
- From the Cover
Patrick E. McGovern, Armen Mirzoian, and Gretchen R. HallSee companion article:
- In This Issue- May 05, 2009
- You have accessEarliest domestication of common millet (Panicum miliaceum) in East Asia extended to 10,000 years agoHouyuan Lu, Jianping Zhang, Kam-biu Liu, Naiqin Wu, Yumei Li, Kunshu Zhou, Maolin Ye, Tianyu Zhang, Haijiang Zhang, Xiaoyan Yang, Licheng Shen, Deke Xu, and Quan Li
See companion article:
Applied Biological Sciences
- Open AccessFlexible electrical recording from cells using nanowire transistor arraysTzahi Cohen-Karni, Brian P. Timko, Lucien E. Weiss, and Charles M. Lieber
Biochemistry
- Open AccessElectrophysiological characterization of LacYJuan J. Garcia-Celma, Irina N. Smirnova, H. Ronald Kaback, and Klaus Fendler
- You have accessMechanism of drug inhibition and drug resistance of influenza A M2 channelRafal M. Pielak, Jason R. Schnell, and James J. Chou
- You have accessExamination of the contributions of size and avidity to the neutralization mechanisms of the anti-HIV antibodies b12 and 4E10Joshua S. Klein, Priyanthi N. P. Gnanapragasam, Rachel P. Galimidi, Christopher P. Foglesong, Anthony P. West Jr, and Pamela J. Bjorkman
- You have accessSTIM protein coupling in the activation of Orai channelsYoujun Wang, Xiaoxiang Deng, Yandong Zhou, Eunan Hendron, Salvatore Mancarella, Michael F. Ritchie, Xiang D. Tang, Yoshihiro Baba, Tomohiro Kurosaki, Yasuo Mori, Jonathan Soboloff, and Donald L. Gill
- You have accessPPARα blocks glucocorticoid receptor α-mediated transactivation but cooperates with the activated glucocorticoid receptor α for transrepression on NF-κBNadia Bougarne, Réjane Paumelle, Sandrine Caron, Nathalie Hennuyer, Roxane Mansouri, Philippe Gervois, Bart Staels, Guy Haegeman, and Karolien De Bosscher
- Open AccessInsights into pilus assembly and secretion from the structure and functional characterization of usher PapCYihua Huang, Barbara S. Smith, Lucy X. Chen, Richard H. G. Baxter, and Johann Deisenhofer
- You have accessFunctional and structural characterization of a dense core secretory granule sorting domain from the PC1/3 proteaseJimmy D. Dikeakos, Paola Di Lello, Marie-Josée Lacombe, Rodolfo Ghirlando, Pascale Legault, Timothy L. Reudelhuber, and James G. Omichinski
- Open AccessCharting the molecular network of the drug target Bcr-AblMarc Brehme, Oliver Hantschel, Jacques Colinge, Ines Kaupe, Melanie Planyavsky, Thomas Köcher, Karl Mechtler, Keiryn L. Bennett, and Giulio Superti-Furga
- Open AccessERα as ligand-independent activator of CDH-1 regulates determination and maintenance of epithelial morphology in breast cancer cellsMaria Dafne Cardamone, Chiara Bardella, Arantxa Gutierrez, Luciano Di Croce, Michael G. Rosenfeld, Maria Flavia Di Renzo, and Michele De Bortoli
- You have accessIdentification and structural basis of the reaction catalyzed by CYP121, an essential cytochrome P450 in Mycobacterium tuberculosisPascal Belin, Marie Hélène Le Du, Alistair Fielding, Olivier Lequin, Mickaël Jacquet, Jean-Baptiste Charbonnier, Alain Lecoq, Robert Thai, Marie Courçon, Cédric Masson, Christophe Dugave, Roger Genet, Jean-Luc Pernodet, and Muriel Gondry
Biophysics and Computational Biology
- You have accessNewcomer insulin secretory granules as a highly calcium-sensitive poolMorten Gram Pedersen and Arthur Sherman
- You have accessCrystal structure of human aquaporin 4 at 1.8 Å and its mechanism of conductanceJoseph D. Ho, Ronald Yeh, Andrew Sandstrom, Ilya Chorny, William E. C. Harries, Rebecca A. Robbins, Larry J. W. Miercke, and Robert M. Stroud
- You have accessSeeded growth of β-amyloid fibrils from Alzheimer's brain-derived fibrils produces a distinct fibril structureAnant K. Paravastu, Isam Qahwash, Richard D. Leapman, Stephen C. Meredith, and Robert Tycko
- You have accessSimulating the electrostatic guidance of the vectorial translocations in hexameric helicases and translocasesHanbin Liu, Yemin Shi, Xiaojiang S. Chen, and Arieh Warshel
- Open AccessDocking for fragment inhibitors of AmpC β-lactamaseDenise G. Teotico, Kerim Babaoglu, Gabriel J. Rocklin, Rafaela S. Ferreira, Anthony M. Giannetti, and Brian K. Shoichet
Cell Biology
- You have accessSpecific glycosphingolipids mediate epithelial-to-mesenchymal transition of human and mouse epithelial cell linesFeng Guan, Kazuko Handa, and Sen-itiroh Hakomori
Developmental Biology
- You have accessEphrinB2 coordinates the formation of a morphological boundary and cell epithelialization during somite segmentationTadayoshi Watanabe, Yuki Sato, Daisuke Saito, Ryosuke Tadokoro, and Yoshiko Takahashi
- You have accessRole of Filia, a maternal effect gene, in maintaining euploidy during cleavage-stage mouse embryogenesisPing Zheng and Jurrien Dean
- Open AccessMuscle hypertrophy driven by myostatin blockade does not require stem/precursor-cell activityHelge Amthor, Anthony Otto, Adeline Vulin, Anne Rochat, Julie Dumonceaux, Luis Garcia, Etienne Mouisel, Christophe Hourdé, Raymond Macharia, Melanie Friedrichs, Frederic Relaix, Peter S. Zammit, Antonios Matsakas, Ketan Patel, and Terence Partridge
- You have accessA right-sided pathway involving FGF8/Snai1 controls asymmetric development of the proepicardium in the chick embryoJan Schlueter and Thomas Brand
Ecology
- You have accessDesorption electrospray ionization mass spectrometry reveals surface-mediated antifungal chemical defense of a tropical seaweed
- From the Cover
Amy L. Lane, Leonard Nyadong, Asiri S. Galhena, Tonya L. Shearer, E. Paige Stout, R. Mitchell Parry, Mark Kwasnik, May D. Wang, Mark E. Hay, Facundo M. Fernandez, and Julia KubanekSee companion article:
- In This Issue- May 05, 2009
Evolution
- Open AccessThe universal distribution of evolutionary rates of genes and distinct characteristics of eukaryotic genes of different apparent ages
- Inaugural Article
Yuri I. Wolf, Pavel S. Novichkov, Georgy P. Karev, Eugene V. Koonin, and David J. LipmanSee companion article:
- In This Issue- May 05, 2009
- You have accessRemarkable resilience of teethHerzl Chai, James J.-W. Lee, Paul J. Constantino, Peter W. Lucas, and Brian R. Lawn
- You have accessDegenerate evolution of the hedgehog gene in a hemichordate lineageAtsuko Sato, Helen White-Cooper, Karen Doggett, and Peter W. H. Holland
- You have accessA continuum of genetic divergence from sympatric host races to species in the pea aphid complexJean Peccoud, Anthony Ollivier, Manuel Plantegenest, and Jean-Christophe Simon
Genetics
- You have accessGenome-wide association and meta-analysis of bipolar disorder in individuals of European ancestryLaura J. Scott, Pierandrea Muglia, Xiangyang Q. Kong, Weihua Guan, Matthew Flickinger, Ruchi Upmanyu, Federica Tozzi, Jun Z. Li, Margit Burmeister, Devin Absher, Robert C. Thompson, Clyde Francks, Fan Meng, Athos Antoniades, Audrey M. Southwick, Alan F. Schatzberg, William E. Bunney, Jack D. Barchas, Edward G. Jones, Richard Day, Keith Matthews, Peter McGuffin, John S. Strauss, James L. Kennedy, Lefkos Middleton, Allen D. Roses, Stanley J. Watson, John B. Vincent, Richard M. Myers, Ann E. Farmer, Huda Akil, Daniel K. Burns, and Michael Boehnke
- Open AccessUpstream open reading frames cause widespread reduction of protein expression and are polymorphic among humansSarah E. Calvo, David J. Pagliarini, and Vamsi K. Mootha
See companion article:
- In This Issue- May 05, 2009
Immunology
- You have accessInterleukin-15 combined with an anti-CD40 antibody provides enhanced therapeutic efficacy for murine models of colon cancerMeili Zhang, Zhengsheng Yao, Sigrid Dubois, Wei Ju, Jürgen R. Müller, and Thomas A. Waldmann
- You have accessWIP is critical for T cell responsiveness to IL-2Severine Le Bras, Michel Massaad, Suresh Koduru, Lalit Kumar, Michiko K. Oyoshi, John Hartwig, and Raif S. Geha
Medical Sciences
- You have accessSpecific function of phosphoinositide 3-kinase beta in the control of DNA replicationMiriam Marqués, Amit Kumar, Ana M. Poveda, Susana Zuluaga, Carmen Hernández, Shaun Jackson, Philippe Pasero, and Ana C. Carrera
- You have accessCoordinated regulation by Shp2 tyrosine phosphatase of signaling events controlling insulin biosynthesis in pancreatic β-cellsSharon S. Zhang, Ergeng Hao, Jianxiu Yu, Wen Liu, Jing Wang, Fred Levine, and Gen-Sheng Feng
- Open AccessDepletion of interfering antibodies in chronic hepatitis C patients and vaccinated chimpanzees reveals broad cross-genotype neutralizing activityPei Zhang, Lilin Zhong, Evi Budo Struble, Hisayoshi Watanabe, Alla Kachko, Kathleen Mihalik, Maria Luisa Virata-Theimer, Harvey J. Alter, Stephen Feinstone, and Marian Major
- You have accessEpistasis among HLA-DRB1, HLA-DQA1, and HLA-DQB1 loci determines multiple sclerosis susceptibilityMatthew R. Lincoln, Sreeram V. Ramagopalan, Michael J. Chao, Blanca M. Herrera, Gabriele C. DeLuca, Sarah-Michelle Orton, David A. Dyment, A Dessa Sadovnick, and George C. Ebers
- Open AccessCardiomyocyte cyclooxygenase-2 influences cardiac rhythm and functionDairong Wang, Vickas V. Patel, Emanuela Ricciotti, Rong Zhou, Mark D. Levin, Ehre Gao, Zhou Yu, Victor A. Ferrari, Min Min Lu, Junwang Xu, Hualei Zhang, Yiqun Hui, Yan Cheng, Nataliya Petrenko, Ying Yu, and Garret A. FitzGerald
- You have accessAntigen-specific Vγ2Vδ2 T effector cells confer homeostatic protection against pneumonic plaque lesionsDan Huang, Crystal Y. Chen, Zahida Ali, Lingyun Shao, Ling Shen, Hank A. Lockman, Roy E. Barnewall, Carol Sabourin, James Eestep, Armin Reichenberg, Martin Hintz, Hassan Jomaa, Richard Wang, and Zheng W. Chen
Microbiology
- Open AccessStatistical estimation of cell-cycle progression and lineage commitment in Plasmodium falciparum reveals a homogeneous pattern of transcription in ex vivo cultureJacob E. Lemieux, Natalia Gomez-Escobar, Avi Feller, Celine Carret, Alfred Amambua-Ngwa, Robert Pinches, Felix Day, Sue A. Kyes, David J. Conway, Chris C. Holmes, and Chris I. Newbold
- Open AccessMinimal molecular constraints for respiratory droplet transmission of an avian–human H9N2 influenza A virusErin M. Sorrell, Hongquan Wan, Yonas Araya, Haichen Song, and Daniel R. Perez
- Open AccessSite-specific integration of adeno-associated virus involves partial duplication of the target locusEls Henckaerts, Nathalie Dutheil, Nadja Zeltner, Steven Kattman, Erik Kohlbrenner, Peter Ward, Nathalie Clément, Patricia Rebollo, Marion Kennedy, Gordon M. Keller, and R. Michael Linden
- You have accessRoles for endocytic trafficking and phosphatidylinositol 4-kinase III alpha in hepatitis C virus replicationKristi L. Berger, Jacob D. Cooper, Nicholas S. Heaton, Rosa Yoon, Todd E. Oakland, Tristan X. Jordan, Guaniri Mateu, Arash Grakoui, and Glenn Randall
- You have accessRegulated expression of the Leishmania major surface virulence factor lipophosphoglycan using conditionally destabilized fusion proteinsLuciana Madeira da Silva, Katherine L. Owens, Silvane M. F. Murta, and Stephen M. Beverley
Neuroscience
- Open AccessDisruption of NMDAR-dependent burst firing by dopamine neurons provides selective assessment of phasic dopamine-dependent behaviorLarry S. Zweifel, Jones G. Parker, Collin J. Lobb, Aundrea Rainwater, Valerie Z. Wall, Jonathan P. Fadok, Martin Darvas, Min J. Kim, Sheri J. Y. Mizumori, Carlos A. Paladini, Paul E. M. Phillips, and Richard D. Palmiter
See companion article:
- In This Issue- May 05, 2009
- Open AccessSpatial ensemble statistics are efficient codes that can be represented with reduced attentionGeorge A. Alvarez and Aude Oliva
- You have accessFlexible neural mechanisms of cognitive control within human prefrontal cortexTodd S. Braver, Jessica L. Paxton, Hannah S. Locke, and Deanna M. Barch
- You have accessFeedback inactivation of D-serine synthesis by NMDA receptor-elicited translocation of serine racemase to the membraneLivia Balan, Veronika N. Foltyn, Martin Zehl, Elena Dumin, Elena Dikopoltsev, Diana Knoh, Yusuke Ohno, Akio Kihara, Ole N. Jensen, Inna S. Radzishevsky, and Herman Wolosker
- You have accessNetrin-1–α3β1 integrin interactions regulate the migration of interneurons through the cortical marginal zoneAmelia Stanco, Charles Szekeres, Nikhil Patel, Sarada Rao, Kenneth Campbell, Jordan A. Kreidberg, Franck Polleux, and E. S. Anton
- You have accessSimplified and effective motor control based on muscle synergies to exploit musculoskeletal dynamicsMax Berniker, Anthony Jarc, Emilio Bizzi, and Matthew C. Tresch
- Open AccessAberrant cleavage of TDP-43 enhances aggregation and cellular toxicityYong-Jie Zhang, Ya-Fei Xu, Casey Cook, Tania F. Gendron, Paul Roettges, Christopher D. Link, Wen-Lang Lin, Jimei Tong, Monica Castanedes-Casey, Peter Ash, Jennifer Gass, Vijayaraghavan Rangachari, Emanuele Buratti, Francisco Baralle, Todd E. Golde, Dennis W. Dickson, and Leonard Petrucelli
- Open AccessEfficient production of mesencephalic dopamine neurons by Lmx1a expression in embryonic stem cellsStina Friling, Elisabet Andersson, Lachlan H. Thompson, Marie E. Jönsson, Josephine B. Hebsgaard, Evanthia Nanou, Zhanna Alekseenko, Ulrika Marklund, Susanna Kjellander, Nikolaos Volakakis, Outi Hovatta, Abdeljabbar El Manira, Anders Björklund, Thomas Perlmann, and Johan Ericson
- Open AccessMolecular dissection of Alzheimer's disease neuropathology by depletion of serum amyloid P componentSimon E. Kolstoe, Basil H. Ridha, Vittorio Bellotti, Nan Wang, Carol V. Robinson, Sebastian J. Crutch, Geoffrey Keir, Riitta Kukkastenvehmas, J. Ruth Gallimore, Winston L. Hutchinson, Philip N. Hawkins, Stephen P. Wood, Martin N. Rossor, and Mark B. Pepys
- Open AccessTranscriptome transfer produces a predictable cellular phenotypeJai-Yoon Sul, Chia-wen K. Wu, Fanyi Zeng, Jeanine Jochems, Miler T. Lee, Tae Kyung Kim, Tiina Peritz, Peter Buckley, David J. Cappelleri, Margaret Maronski, Minsun Kim, Vijay Kumar, David Meaney, Junhyong Kim, and James Eberwine
- You have accessA gain in GABAA receptor synaptic strength in thalamus reduces oscillatory activity and absence seizuresClaude M. Schofield, Max Kleiman-Weiner, Uwe Rudolph, and John R. Huguenard
Physiology
- You have accessAblation of triadin causes loss of cardiac Ca2+ release units, impaired excitation–contraction coupling, and cardiac arrhythmiasNagesh Chopra, Tao Yang, Parisa Asghari, Edwin D. Moore, Sabine Huke, Brandy Akin, Robert A. Cattolica, Claudio F. Perez, Thinn Hlaing, Barbara E. C. Knollmann-Ritschel, Larry R. Jones, Isaac N. Pessah, Paul D. Allen, Clara Franzini-Armstrong, and Björn C. Knollmann
- Open AccessHv1 proton channels are required for high-level NADPH oxidase-dependent superoxide production during the phagocyte respiratory burstI. Scott Ramsey, Evelyne Ruchti, J. Stefan Kaczmarek, and David E. Clapham
Plant Biology
- You have accessThree related receptor-like kinases are required for optimal cell elongation in Arabidopsis thalianaHongqing Guo, Lei Li, Huaxun Ye, Xiaofei Yu, Alexandria Algreen, and Yanhai Yin
- You have accessPIF3 is a repressor of chloroplast developmentPatrick G. Stephenson, Christian Fankhauser, and Matthew J. Terry
- You have accessPhytochromes promote seedling light responses by inhibiting four negatively-acting phytochrome-interacting factorsJieun Shin, Keunhwa Kim, Hyojin Kang, Ismayil S. Zulfugarov, Gabyong Bae, Choon-Hwan Lee, Doheon Lee, and Giltsu Choi
- You have accessIntegration of evolutionary and desolvation energy analysis identifies functional sites in a plant immunity proteinManuela Casasoli, Luca Federici, Francesco Spinelli, Adele Di Matteo, Nicoletta Vella, Flavio Scaloni, Juan Fernandez-Recio, Felice Cervone, and Giulia De Lorenzo
Population Biology
- You have accessAverting epidemics of extensively drug-resistant tuberculosisSanjay Basu, Gerald H. Friedland, Jan Medlock, Jason R. Andrews, N. Sarita Shah, Neel R. Gandhi, Anthony Moll, Prashini Moodley, A. Willem Sturm, and Alison P. Galvani
Commentaries
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