Research Article

The iron-sulfur clusters of dehydratases are primary intracellular targets of copper toxicity

Lee Macomber and James A. Imlay
PNAS May 19, 2009 106 (20) 8344-8349; https://doi.org/10.1073/pnas.0812808106

  1. Edited by Irwin Fridovich, Duke University Medical Center, Durham, NC, and approved March 31, 2009 (received for review December 16, 2008)

Online Impact

 

Article Information

vol. 106 no. 20 8344-8349
DOI: 
https://doi.org/10.1073/pnas.0812808106
PubMed: 
19416816
Published By: 
National Academy of Sciences
Print ISSN: 
0027-8424
Online ISSN: 
1091-6490
History: 
  • Published in issue May 19, 2009.
  • Published first May 4, 2009.
Copyright & Usage: 
© 2009

Author Information

  1. Lee Macomber and
  2. James A. Imlay,1
  1. Department of Microbiology, University of Illinois, Urbana, IL 61801

  1. Edited by Irwin Fridovich, Duke University Medical Center, Durham, NC, and approved March 31, 2009 (received for review December 16, 2008)

Footnotes

  • 1To whom correspondence should be addressed. E-mail: jimlay{at}illinois.edu

  • Author contributions: L.M. and J.A.I. designed research; L.M. performed research; L.M. and J.A.I. analyzed data; and L.M. and J.A.I. wrote the paper.

  • The authors declare no conflict of interest.

  • This article is a PNAS Direct Submission.

  • This article contains supporting information online at www.pnas.org/cgi/content/full/0812808106/DCSupplemental.

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Article usage: May 2009 to February 2020

AbstractFullPdf
May 2009364384448
Jun 2009414103117
Jul 20091508197
Aug 2009974343
Sep 20091244565
Oct 2009864148
Nov 2009753636
Dec 2009623529
Total 20094651468883
Jan 2010582838
Feb 2010457042
Mar 2010584530
Apr 2010374126
May 2010644023
Jun 2010394223
Jul 2010483229
Aug 2010412518
Sep 2010435138
Oct 2010366033
Nov 2010384126
Dec 2010243724
Total 2010531512350
Jan 2011294134
Feb 2011212216
Mar 2011282423
Apr 2011181512
May 2011233133
Jun 2011402730
Jul 2011252442
Aug 2011232432
Sep 2011444726
Oct 2011333442
Nov 2011592527
Dec 2011502822
Total 2011393342339
Jan 2012373327
Feb 2012583333
Mar 2012533629
Apr 2012393538
May 2012392732
Jun 2012362922
Jul 2012571926
Aug 2012412133
Sep 2012472820
Oct 2012412238
Nov 2012433738
Dec 2012412532
Total 2012532345368
Jan 2013433732
Feb 2013383528
Mar 2013554146
Apr 2013543727
May 2013542537
Jun 2013333027
Jul 2013414330
Aug 2013243117
Sep 2013563132
Oct 2013534449
Nov 2013473821
Dec 2013383325
Total 2013536425371
Jan 2014313818
Feb 2014452726
Mar 2014667945
Apr 2014774437
May 2014323422
Jun 2014383834
Jul 2014594533
Aug 2014352616
Sep 2014374038
Oct 2014725136
Nov 2014233231
Dec 2014412827
Total 2014556482363
Jan 2015312521
Feb 2015474121
Mar 2015484224
Apr 2015496733
May 2015554023
Jun 2015273023
Jul 2015443743
Aug 2015433423
Sep 2015765240
Oct 2015364122
Nov 2015583240
Dec 2015502419
Total 2015564465332
Jan 2016664236
Feb 2016494029
Mar 2016724348
Apr 2016504928
May 2016464129
Jun 2016393926
Jul 2016643837
Aug 2016564833
Sep 2016913837
Oct 2016845538
Nov 2016523727
Dec 2016442327
Total 2016713493395
Jan 2017504630
Feb 2017794332
Mar 2017645634
Apr 2017562931
May 2017734325
Jun 2017353416
Jul 2017272511
Aug 2017483632
Sep 2017363839
Oct 2017854432
Nov 2017515034
Dec 2017383534
Total 2017642479350
Jan 2018414327
Feb 201816416230
Mar 2018897154
Apr 2018846341
May 2018797344
Jun 2018785526
Jul 2018734728
Aug 2018696424
Sep 2018744526
Oct 2018356829
Nov 2018308549
Dec 2018297429
Total 2018845850407
Jan 20192711425
Feb 2019156726
Mar 2019348153
Apr 2019309935
May 2019349542
Jun 2019238229
Jul 201977233
Aug 2019189451
Sep 2019238041
Oct 2019419337
Nov 2019306243
Dec 2019176127
Total 20192991000442
Jan 2020279040
Feb 202095228
Total 20203614268
Total1029860034668
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The iron-sulfur clusters of dehydratases are primary intracellular targets of copper toxicity
Lee Macomber, James A. Imlay
Proceedings of the National Academy of Sciences May 2009, 106 (20) 8344-8349; DOI: 10.1073/pnas.0812808106
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Proceedings of the National Academy of Sciences: 106 (20)
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