Evolution of an antifreeze protein by neofunctionalization under escape from adaptive conflict
- aKey Laboratory of Molecular and Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China;
- bGraduate College of Chinese Academy of Sciences, Chinese Academy of Sciences, Beijing 100101, China; and
- cDepartment of Animal Biology, University of Illinois, Urbana, IL 61801
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Edited by Sean B. Carroll, University of Wisconsin, Madison, WI, and approved November 2, 2010 (received for review June 5, 2010)

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Article Information
- Published in issue December 14, 2010.
- Published first November 29, 2010.
Author Information
- aKey Laboratory of Molecular and Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China;
- bGraduate College of Chinese Academy of Sciences, Chinese Academy of Sciences, Beijing 100101, China; and
- cDepartment of Animal Biology, University of Illinois, Urbana, IL 61801
Edited by Sean B. Carroll, University of Wisconsin, Madison, WI, and approved November 2, 2010 (received for review June 5, 2010)
Footnotes
- 1To whom correspondence may be addressed. E-mail: lbchen{at}genetics.ac.cn or c-cheng{at}uiuc.edu.
Author contributions: C.-H.C.C. and L.C. designed research; C.D. performed research; C.D., H.Y., X.H., and L.C. analyzed data; and C.-H.C.C. and L.C. wrote the paper.
The authors declare no conflict of interest.
This article is a PNAS Direct Submission.
Data deposition: The sequences reported in this paper have been deposited in the GenBank database (LdBAC002 accession no. GQ368892, LdBAC008 accession no. GQ368894, and LdBAC004 accession no. GQ368893).
This article contains supporting information online at www.pnas.org/lookup/suppl/doi:10.1073/pnas.1007883107/-/DCSupplemental.
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