New Research In
Physical Sciences
Social Sciences
Featured Portals
Articles by Topic
Biological Sciences
Featured Portals
Articles by Topic
- Agricultural Sciences
- Anthropology
- Applied Biological Sciences
- Biochemistry
- Biophysics and Computational Biology
- Cell Biology
- Developmental Biology
- Ecology
- Environmental Sciences
- Evolution
- Genetics
- Immunology and Inflammation
- Medical Sciences
- Microbiology
- Neuroscience
- Pharmacology
- Physiology
- Plant Biology
- Population Biology
- Psychological and Cognitive Sciences
- Sustainability Science
- Systems Biology
Table of Contents
December 28, 2010; vol. 107 no. 52
This Week in PNAS
Letters (Online Only)
- You have accessReply to Bodenstein: Contextual data about the relative scale of opposing scientific communitiesWilliam R. L. Anderegg, James W. Prall, and Jacob Harold
- You have accessIt is not necessarily YY1—the frequently forgotten Yin-Yang-2 transcription factorMartin Klar
- You have accessReply to Klar: Key role of YY1 in neoangiogenesisFilomena de Nigris, Valeria Crudele, Alfonso Giovane, Amelia Casamassimi, Hermes J. Garban, Diana C. Marquez-Garban, Toshio Hayashi, Louis J. Ignarro, and Claudio Napoli
Perspective
- You have accessEvolving concepts of specificity in immune reactionsHerman N. Eisen and Arup K. Chakraborty
Profile
Feature Article
- You have accessSyntaxin N-terminal peptide motif is an initiation factor for the assembly of the SNARE–Sec1/Munc18 membrane fusion complex
- From the Cover
Shailendra S. Rathore, Eric G. Bend, Haijia Yu, Marc Hammarlund, Erik M. Jorgensen, and Jingshi ShenSee companion article:
- Testing the SNARE/SM protein model of membrane fusion- Dec 17, 2010
Physical Sciences
Applied Physical Sciences
- You have accessWhispering-gallery mode resonators for highly unidirectional laser action
- From the Cover
Qi Jie Wang, Changling Yan, Nanfang Yu, Julia Unterhinninghofen, Jan Wiersig, Christian Pflügl, Laurent Diehl, Tadataka Edamura, Masamichi Yamanishi, Hirofumi Kan, and Federico CapassoSee companion article:
- You have accessDynamic self-assembly and control of microfluidic particle crystalsWonhee Lee, Hamed Amini, Howard A. Stone, and Dino Di Carlo
Chemistry
- You have accessDefinition of the intermediates and mechanism of the anticancer drug bleomycin using nuclear resonance vibrational spectroscopy and related methodsLei V. Liu, Caleb B. Bell III, Shaun D. Wong, Samuel A. Wilson, Yeonju Kwak, Marina S. Chow, Jiyong Zhao, Keith O. Hodgson, Britt Hedman, and Edward I. Solomon
- You have accessStrongly bound citrate stabilizes the apatite nanocrystals in bone
- From the Cover
Y.-Y. Hu, A. Rawal, and K. Schmidt-RohrSee companion article:
- You have accessMorphologically controlled synthesis of colloidal upconversion nanophosphors and their shape-directed self-assemblyXingchen Ye, Joshua E. Collins, Yijin Kang, Jun Chen, Daniel T. N. Chen, Arjun G. Yodh, and Christopher B. Murray
- You have accessRapid DNA–protein cross-linking and strand scission by an abasic site in a nucleosome core particleJonathan T. Sczepanski, Remus S. Wong, Jeffrey N. McKnight, Gregory D. Bowman, and Marc M. Greenberg
- You have accessStructural space of protein–protein interfaces is degenerate, close to complete, and highly connectedMu Gao and Jeffrey Skolnick
- You have accessMechanism of tungsten-dependent acetylene hydratase from quantum chemical calculationsRong-Zhen Liao, Jian-Guo Yu, and Fahmi Himo
Computer Sciences
- Open AccessInferring social ties from geographic coincidencesDavid J. Crandall, Lars Backstrom, Dan Cosley, Siddharth Suri, Daniel Huttenlocher, and Jon Kleinberg
Environmental Sciences
- You have accessNorth Atlantic summers have warmed more than winters since 1353, and the response of marine zooplanktonNicholas A. Kamenos
Geology
- You have accessBaseline intrinsic flammability of Earth’s ecosystems estimated from paleoatmospheric oxygen over the past 350 million yearsClaire M. Belcher, Jonathan M. Yearsley, Rory M. Hadden, Jennifer C. McElwain, and Guillermo Rein
Mathematics
Physics
- You have accessTransport properties of glass-forming liquids suggest that dynamic crossover temperature is as important as the glass transition temperatureFrancesco Mallamace, Caterina Branca, Carmelo Corsaro, Nancy Leone, Jeroen Spooren, Sow-Hsin Chen, and H. Eugene Stanley
Social Sciences
Economic Sciences
- You have accessThe happiness–income paradox revisitedRichard A. Easterlin, Laura Angelescu McVey, Malgorzata Switek, Onnicha Sawangfa, and Jacqueline Smith Zweig
Political Sciences
- You have accessIdentifying barriers to Muslim integration in France
- Inaugural Article
Claire L. Adida, David D. Laitin, and Marie-Anne ValfortSee companion article:
- Profile of David D. Laitin- Nov 21, 2011
Psychological and Cognitive Sciences
- You have accessPeople believe they have more free will than othersEmily Pronin and Matthew B. Kugler
- You have accessSleep deprivation impairs precision of waggle dance signaling in honey beesBarrett A. Klein, Arno Klein, Margaret K. Wray, Ulrich G. Mueller, and Thomas D. Seeley
Social Sciences
- Open AccessInferring social ties from geographic coincidencesDavid J. Crandall, Lars Backstrom, Dan Cosley, Siddharth Suri, Daniel Huttenlocher, and Jon Kleinberg
Sustainability Science
- You have accessCausal inference methods to study nonrandomized, preexisting development interventionsBenjamin F. Arnold, Ranjiv S. Khush, Padmavathi Ramaswamy, Alicia G. London, Paramasivan Rajkumar, Prabhakar Ramaprabha, Natesan Durairaj, Alan E. Hubbard, Kalpana Balakrishnan, and John M. Colford Jr.
Biological Sciences
Biochemistry
- You have accessRapid DNA–protein cross-linking and strand scission by an abasic site in a nucleosome core particleJonathan T. Sczepanski, Remus S. Wong, Jeffrey N. McKnight, Gregory D. Bowman, and Marc M. Greenberg
- You have accessNMR analysis of the αIIbβ3 cytoplasmic interaction suggests a mechanism for integrin regulationDouglas G. Metcalf, David T. Moore, Yibing Wu, Joseph M. Kielec, Kathleen Molnar, Kathleen G. Valentine, A. Joshua Wand, Joel S. Bennett, and William F. DeGrado
- Open AccessAutoinhibition of DNA cleavage mediated by RAG1 and RAG2 is overcome by an epigenetic signal in V(D)J recombinationGabrielle J. Grundy, Wei Yang, and Martin Gellert
- You have accessDiscovery of a minimal form of RNase P in Pyrobaculum
- From the Cover
Lien B. Lai, Patricia P. Chan, Aaron E. Cozen, David L. Bernick, James W. Brown, Venkat Gopalan, and Todd M. LoweSee companion article:
- Discovery of a mini-RNase P in archaea- Dec 16, 2010
- You have accessStructure of RavA MoxR AAA+ protein reveals the design principles of a molecular cage modulating the inducible lysine decarboxylase activityMajida El Bakkouri, Irina Gutsche, Usheer Kanjee, Boyu Zhao, Miao Yu, Gael Goret, Guy Schoehn, Wim P. Burmeister, and Walid A. Houry
- You have accessStructural basis for active site closure by the poliovirus RNA-dependent RNA polymerasePeng Gong and Olve B. Peersen
- You have accessStructural basis of flocculin-mediated social behavior in yeastMaik Veelders, Stefan Brückner, Dimitri Ott, Carlo Unverzagt, Hans-Ulrich Mösch, and Lars-Oliver Essen
Biophysics and Computational Biology
- You have accessDefinition of the intermediates and mechanism of the anticancer drug bleomycin using nuclear resonance vibrational spectroscopy and related methodsLei V. Liu, Caleb B. Bell III, Shaun D. Wong, Samuel A. Wilson, Yeonju Kwak, Marina S. Chow, Jiyong Zhao, Keith O. Hodgson, Britt Hedman, and Edward I. Solomon
- You have accessStrongly bound citrate stabilizes the apatite nanocrystals in bone
- From the Cover
Y.-Y. Hu, A. Rawal, and K. Schmidt-RohrSee companion article:
- You have accessStructural space of protein–protein interfaces is degenerate, close to complete, and highly connectedMu Gao and Jeffrey Skolnick
- You have accessMechanism of tungsten-dependent acetylene hydratase from quantum chemical calculationsRong-Zhen Liao, Jian-Guo Yu, and Fahmi Himo
- You have accessPerturbing the folding energy landscape of the bacterial immunity protein Im7 by site-specific N-linked glycosylationMark M. Chen, Alice I. Bartlett, Paul S. Nerenberg, Claire T. Friel, Christian P. R. Hackenberger, Collin M. Stultz, Sheena E. Radford, and Barbara Imperiali
- You have accessRobust circadian clocks from coupled protein-modification and transcription–translation cyclesDavid Zwicker, David K. Lubensky, and Pieter Rein ten Wolde
- You have accessFunctional dynamics in the voltage-dependent anion channelSaskia Villinger, Rodolfo Briones, Karin Giller, Ulrich Zachariae, Adam Lange, Bert L. de Groot, Christian Griesinger, Stefan Becker, and Markus Zweckstetter
Cell Biology
- You have accessSyntaxin N-terminal peptide motif is an initiation factor for the assembly of the SNARE–Sec1/Munc18 membrane fusion complex
- From the Cover
Shailendra S. Rathore, Eric G. Bend, Haijia Yu, Marc Hammarlund, Erik M. Jorgensen, and Jingshi ShenSee companion article:
- Testing the SNARE/SM protein model of membrane fusion- Dec 17, 2010
- You have accessL3MBTL1 polycomb protein, a candidate tumor suppressor in del(20q12) myeloid disorders, is essential for genome stabilityNadia Gurvich, Fabiana Perna, Andrea Farina, Francesca Voza, Silvia Menendez, Jerard Hurwitz, and Stephen D. Nimer
Developmental Biology
- You have accessmicroRNA miR-275 is indispensable for blood digestion and egg development in the mosquito Aedes aegypti
- Inaugural Article
- From the Cover
Bart Bryant, Warren Macdonald, and Alexander S. RaikhelSee companion article:
- Profile of Alexander S. Raikhel- Dec 20, 2010
- You have accessSpatial restriction of receptor tyrosine kinase activity through a polarized endocytic cycle controls border cell migrationGloria Assaker, Damien Ramel, Stefanie K. Wculek, Marcos González-Gaitán, and Gregory Emery
- Open AccessSwitching of the core structures of glycosphingolipids from globo- and lacto- to ganglio-series upon human embryonic stem cell differentiationYuh-Jin Liang, Huan-Hsien Kuo, Chi-Hung Lin, Yen-Ying Chen, Bei-Chia Yang, Yuan-Yuan Cheng, Alice L. Yu, Kay-Hooi Khoo, and John Yu
Environmental Sciences
- You have accessBaseline intrinsic flammability of Earth’s ecosystems estimated from paleoatmospheric oxygen over the past 350 million yearsClaire M. Belcher, Jonathan M. Yearsley, Rory M. Hadden, Jennifer C. McElwain, and Guillermo Rein
Evolution
- Open AccessConservation and canalization of gene expression during angiosperm diversification accompany the origin and evolution of the flowerAndré S. Chanderbali, Mi-Jeong Yoo, Laura M. Zahn, Samuel F. Brockington, P. Kerr Wall, Matthew A. Gitzendanner, Victor A. Albert, James Leebens-Mack, Naomi S. Altman, Hong Ma, Claude W. dePamphilis, Douglas E. Soltis, and Pamela S. Soltis
- You have accessExpression patterns of neural genes in Euperipatoides kanangrensis suggest divergent evolution of onychophoran and euarthropod neurogenesisBo Joakim Eriksson and Angelika Stollewerk
Genetics
- You have accessDNA tandem repeat instability in the Escherichia coli chromosome is stimulated by mismatch repair at an adjacent CAG·CTG trinucleotide repeatJohn K. Blackwood, Ewa A. Okely, Rabaab Zahra, John K. Eykelenboom, and David R. F. Leach
Immunology
- Open AccessAntigen-bearing dendritic cells regulate the diverse pattern of memory CD8 T-cell development in different tissuesChing-Hung Shen, Oezcan Talay, Vinay S. Mahajan, Ilya B. Leskov, Herman N. Eisen, and Jianzhu Chen
- Open AccessT-cell cytokines differentially control human monocyte antimicrobial responses by regulating vitamin D metabolismKristina Edfeldt, Philip T. Liu, Rene Chun, Mario Fabri, Mirjam Schenk, Matthew Wheelwright, Caroline Keegan, Stephan R. Krutzik, John S. Adams, Martin Hewison, and Robert L. Modlin
Medical Sciences
- You have accessRelationship of farm salmon, sea lice, and wild salmon populationsGary D. Marty, Sonja M. Saksida, and Terrance J. Quinn II
- You have accessCausal inference methods to study nonrandomized, preexisting development interventionsBenjamin F. Arnold, Ranjiv S. Khush, Padmavathi Ramaswamy, Alicia G. London, Paramasivan Rajkumar, Prabhakar Ramaprabha, Natesan Durairaj, Alan E. Hubbard, Kalpana Balakrishnan, and John M. Colford Jr.
- You have accessChemical generation of bispecific antibodiesVenkata R. Doppalapudi, Jie Huang, Dingguo Liu, Ping Jin, Bin Liu, Lingna Li, Joel Desharnais, Crystal Hagen, Nancy J. Levin, Michael J. Shields, Michelle Parish, Robert E. Murphy, Joselyn Del Rosario, Bryan D. Oates, Jing-Yu Lai, Marla J. Matin, Zemeda Ainekulu, Abhijit Bhat, Curt W. Bradshaw, Gary Woodnutt, Richard A. Lerner, and Rodney W. Lappe
- You have accessIL-4/STAT6 immune axis regulates peripheral nutrient metabolism and insulin sensitivityRoberto R. Ricardo-Gonzalez, Alex Red Eagle, Justin I. Odegaard, Hani Jouihan, Christine R. Morel, Jose E. Heredia, Lata Mukundan, Davina Wu, Richard M. Locksley, and Ajay Chawla
- You have accessRegulation of global genome nucleotide excision repair by SIRT1 through xeroderma pigmentosum CMei Ming, Christopher R. Shea, Xiumei Guo, Xiaoling Li, Keyoumars Soltani, Weinong Han, and Yu-Ying He
- You have accessFollicle-stimulating hormone increases bone mass in female miceCharles M. Allan, Robert Kalak, Colin R. Dunstan, Kirsten J. McTavish, Hong Zhou, David J. Handelsman, and Markus J. Seibel
Microbiology
- You have accessStructure of a core fragment of glycoprotein H from pseudorabies virus in complex with antibodyMarija Backovic, Rebecca M. DuBois, Joseph J. Cockburn, Andrew J. Sharff, Marie-Christine Vaney, Harald Granzow, Barbara G. Klupp, Gerard Bricogne, Thomas C. Mettenleiter, and Felix A. Rey
- You have accessCrystal structure of the Epstein-Barr virus (EBV) glycoprotein H/glycoprotein L (gH/gL) complexHisae Matsuura, Austin N. Kirschner, Richard Longnecker, and Theodore S. Jardetzky
- You have accessAttenuation of innate immunity by cytomegalovirus IL-10 establishes a long-term deficit of adaptive antiviral immunityW. L. William Chang and Peter A. Barry
- You have accessTransfer of a prion strain to different hosts leads to emergence of strain variantsSukhvir P. Mahal, Shawn Browning, Jiali Li, Irena Suponitsky-Kroyter, and Charles Weissmann
Neuroscience
- You have accessFGF-1 induces ATP release from spinal astrocytes in culture and opens pannexin and connexin hemichannelsJuan M. Garré, Mauricio A. Retamal, Patricia Cassina, Luis Barbeito, Feliksas F. Bukauskas, Juan C. Sáez, Michael V. L. Bennett, and Verónica Abudara
- You have accessThalamocortical model for a propofol-induced α-rhythm associated with loss of consciousnessShiNung Ching, Aylin Cimenser, Patrick L. Purdon, Emery N. Brown, and Nancy J. Kopell
- Open AccessNegative regulation of ciliary length by ciliary male germ cell-associated kinase (Mak) is required for retinal photoreceptor survivalYoshihiro Omori, Taro Chaya, Kimiko Katoh, Naoko Kajimura, Shigeru Sato, Koichiro Muraoka, Shinji Ueno, Toshiyuki Koyasu, Mineo Kondo, and Takahisa Furukawa
- You have accessDifferential brain activity states during the perception and nonperception of illusory motion as revealed by magnetoencephalographyDavid A. Crowe, Arthur C. Leuthold, and Apostolos P. Georgopoulos
- Open AccessLongitudinal evidence for diminished frontal cortex function in agingLars Nyberg, Alireza Salami, Mikael Andersson, Johan Eriksson, Grégoria Kalpouzos, Karolina Kauppi, Johanna Lind, Sara Pudas, Jonas Persson, and Lars-Göran Nilsson
- You have accessCBP gene transfer increases BDNF levels and ameliorates learning and memory deficits in a mouse model of Alzheimer's diseaseAntonella Caccamo, Monica A. Maldonado, Alex F. Bokov, Smita Majumder, and Salvatore Oddo
- You have accessTiming and completion of puberty in female mice depend on estrogen receptor α-signaling in kisspeptin neuronsChristian Mayer, Maricedes Acosta-Martinez, Sharon L. Dubois, Andrew Wolfe, Sally Radovick, Ulrich Boehm, and Jon E. Levine
- You have accessDifferential dynamics and activity-dependent regulation of α- and β-neurexins at developing GABAergic synapsesYu Fu and Z. Josh Huang
Physiology
- You have accessSleep deprivation impairs precision of waggle dance signaling in honey beesBarrett A. Klein, Arno Klein, Margaret K. Wray, Ulrich G. Mueller, and Thomas D. Seeley
- Open AccessKCNE1 alters the voltage sensor movements necessary to open the KCNQ1 channel gateJeremiah D. Osteen, Carlos Gonzalez, Kevin J. Sampson, Vivek Iyer, Santiago Rebolledo, H. Peter Larsson, and Robert S. Kass
Plant Biology
- You have accessArabidopsis BRCA2 and RAD51 proteins are specifically involved in defense gene transcription during plant immune responsesShui Wang, Wendy E. Durrant, Junqi Song, Natalie W. Spivey, and Xinnian Dong
- You have accessHydraulic trade-offs and space filling enable better predictions of vascular structure and function in plantsV. M. Savage, L. P. Bentley, B. J. Enquist, J. S. Sperry, D. D. Smith, P. B. Reich, and E. I. von Allmen
- You have accessATP-binding cassette-like transporters are involved in the transport of lignin precursors across plasma and vacuolar membranesYu-Chen Miao and Chang-Jun Liu
- You have accessSpatio-temporal sequence of cross-regulatory events in root meristem growthEmanuele Scacchi, Paula Salinas, Bojan Gujas, Luca Santuari, Naden Krogan, Laura Ragni, Thomas Berleth, and Christian S. Hardtke
- You have accessAuxin transport through PIN-FORMED 3 (PIN3) controls shade avoidance and fitness during competitionDiederik H. Keuskamp, Stephan Pollmann, Laurentius A. C. J. Voesenek, Anton J. M. Peeters, and Ronald Pierik
Sustainability Science
- You have accessRelationship of farm salmon, sea lice, and wild salmon populationsGary D. Marty, Sonja M. Saksida, and Terrance J. Quinn II
Systems Biology
- Open AccessInactivation of p53 in breast cancers correlates with stem cell transcriptional signaturesHideaki Mizuno, Benjamin T. Spike, Geoffrey M. Wahl, and Arnold J. Levine
Commentaries
See companion article:
See companion article:
See companion article:
See companion article:
See companion article: