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Table of Contents

April 05, 2011; vol. 108 no. 14

This Week in PNAS

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    In This Issue
    PNAS April 5, 2011 108 (14) 5473-5474; https://doi.org/10.1073/iti1411108

Commentaries

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    Evidence for the importance of measuring total brain activity in neuroimaging
    Fahmeed Hyder and Douglas L. Rothman
    PNAS April 5, 2011 108 (14) 5475-5476; https://doi.org/10.1073/pnas.1102026108

    See companion article:

    • Brain-state–independent neural representation of peripheral stimulation in rat olfactory bulb
      - Feb 14, 2011
  • You have access
    The birth of ant genomics
    Raghavendra Gadagkar
    PNAS April 5, 2011 108 (14) 5477-5478; https://doi.org/10.1073/pnas.1100765108

    See companion article:

    • Draft genome of the red harvester ant Pogonomyrmex barbatus
      - Jan 31, 2011
    • The genome of the fire ant Solenopsis invicta
      - Jan 31, 2011
    • Draft genome of the globally widespread and invasive Argentine ant (Linepithema humile)
      - Jan 31, 2011

PNAS Plus (Author Summary)

  • Biological Sciences

    • Cell Biology

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        A vesicle carrier that mediates peroxisome protein traffic from the endoplasmic reticulum
        Sheung Kwan Lam, Naofumi Yoda, and Randy Schekman
        PNAS April 5, 2011 108 (14) E51-E52; https://doi.org/10.1073/pnas.1103526108

        See companion article:

        • A vesicle carrier that mediates peroxisome protein traffic from the endoplasmic reticulum
          - Nov 22, 2010

QnAs

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    QnAs with James E. Haber
    Beth Azar
    PNAS April 5, 2011 108 (14) 5479; https://doi.org/10.1073/pnas.1103328108

Spatial Cyberinfrastructure Special Feature (free online)

  • Introduction

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      The emergence of spatial cyberinfrastructure
      • From the Cover
      Dawn J. Wright and Shaowen Wang
      PNAS April 5, 2011 108 (14) 5488-5491; https://doi.org/10.1073/pnas.1103051108
  • Perspective

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      Users as essential contributors to spatial cyberinfrastructures
      Barbara S. Poore
      PNAS April 5, 2011 108 (14) 5510-5515; https://doi.org/10.1073/pnas.0907677108
  • Research Articles

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      Spatial characterization of the meltwater field from icebergs in the Weddell Sea
      John J. Helly, Ronald S. Kaufmann, Maria Vernet, and Gordon R. Stephenson
      PNAS April 5, 2011 108 (14) 5492-5497; https://doi.org/10.1073/pnas.0909306108
    • You have access
      Using spatial principles to optimize distributed computing for enabling the physical science discoveries
      Chaowei Yang, Huayi Wu, Qunying Huang, Zhenlong Li, and Jing Li
      PNAS April 5, 2011 108 (14) 5498-5503; https://doi.org/10.1073/pnas.0909315108
    • You have access
      Spatial cyberinfrastructures, ontologies, and the humanities
      Renee E. Sieber, Christopher C. Wellen, and Yuan Jin
      PNAS April 5, 2011 108 (14) 5504-5509; https://doi.org/10.1073/pnas.0911052108

Physical Sciences

  • Applied Mathematics

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      Growth, geometry, and mechanics of a blooming lily
      • From the Cover
      Haiyi Liang and L. Mahadevan
      PNAS April 5, 2011 108 (14) 5516-5521; https://doi.org/10.1073/pnas.1007808108
    • You have access
      A competitive network theory of species diversity
      Stefano Allesina and Jonathan M. Levine
      PNAS April 5, 2011 108 (14) 5638-5642; https://doi.org/10.1073/pnas.1014428108
    • You have access
      How frequency and intensity shape diversity–disturbance relationships
      Adam D. Miller, Stephen H. Roxburgh, and Katriona Shea
      PNAS April 5, 2011 108 (14) 5643-5648; https://doi.org/10.1073/pnas.1018594108
  • Applied Physical Sciences

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      Modification of deeply buried hydrophobic interfaces by ionic surfactants
      Lilach Tamam, Diego Pontoni, Zvi Sapir, Shai Yefet, Eli Sloutskin, Benjamin M. Ocko, Harald Reichert, and Moshe Deutsch
      PNAS April 5, 2011 108 (14) 5522-5525; https://doi.org/10.1073/pnas.1014100108
  • Chemistry

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      Atomic-scale insight and design principles for turbine engine thermal barrier coatings from theory
      • Inaugural Article
      • From the Cover
      Kristen A. Marino, Berit Hinnemann, and Emily A. Carter
      PNAS April 5, 2011 108 (14) 5480-5487; https://doi.org/10.1073/pnas.1102426108
    • Open Access
      Primordial synthesis of amines and amino acids in a 1958 Miller H2S-rich spark discharge experiment
      Eric T. Parker, Henderson J. Cleaves, Jason P. Dworkin, Daniel P. Glavin, Michael Callahan, Andrew Aubrey, Antonio Lazcano, and Jeffrey L. Bada
      PNAS April 5, 2011 108 (14) 5526-5531; https://doi.org/10.1073/pnas.1019191108
    • You have access
      Vibron and phonon hybridization in dielectric nanostructures
      Thomas C. Preston and Ruth Signorell
      PNAS April 5, 2011 108 (14) 5532-5536; https://doi.org/10.1073/pnas.1100170108
    • You have access
      Malleability of folding intermediates in the homeodomain superfamily
      Wiktor Banachewicz, Tomasz L. Religa, R. D. Schaeffer, Valerie Daggett, and Alan R. Fersht
      PNAS April 5, 2011 108 (14) 5596-5601; https://doi.org/10.1073/pnas.1101752108
    • You have access
      Histone deacetylase inhibitor treatment dramatically reduces cholesterol accumulation in Niemann-Pick type C1 mutant human fibroblasts
      Nina H. Pipalia, Casey C. Cosner, Amy Huang, Anamitra Chatterjee, Pauline Bourbon, Nathan Farley, Paul Helquist, Olaf Wiest, and Frederick R. Maxfield
      PNAS April 5, 2011 108 (14) 5620-5625; https://doi.org/10.1073/pnas.1014890108
  • Computer Sciences

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      Using spatial principles to optimize distributed computing for enabling the physical science discoveries
      Chaowei Yang, Huayi Wu, Qunying Huang, Zhenlong Li, and Jing Li
      PNAS April 5, 2011 108 (14) 5498-5503; https://doi.org/10.1073/pnas.0909315108
  • Geology

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      Eastern Equatorial Pacific productivity and related-CO2 changes since the last glacial period
      Eva Calvo, Carles Pelejero, Leopoldo D. Pena, Isabel Cacho, and Graham A. Logan
      PNAS April 5, 2011 108 (14) 5537-5541; https://doi.org/10.1073/pnas.1009761108
    • Open Access
      Towards a quantitative understanding of the late Neoproterozoic carbon cycle
      Christian J. Bjerrum and Donald E. Canfield
      PNAS April 5, 2011 108 (14) 5542-5547; https://doi.org/10.1073/pnas.1101755108
  • Geophysics

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      Spatial characterization of the meltwater field from icebergs in the Weddell Sea
      John J. Helly, Ronald S. Kaufmann, Maria Vernet, and Gordon R. Stephenson
      PNAS April 5, 2011 108 (14) 5492-5497; https://doi.org/10.1073/pnas.0909306108

Social Sciences

  • Psychological and Cognitive Sciences

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      Potential social interactions are important to social attention
      Kaitlin E. W. Laidlaw, Tom Foulsham, Gustav Kuhn, and Alan Kingstone
      PNAS April 5, 2011 108 (14) 5548-5553; https://doi.org/10.1073/pnas.1017022108
  • Social Sciences

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      Spatial cyberinfrastructures, ontologies, and the humanities
      Renee E. Sieber, Christopher C. Wellen, and Yuan Jin
      PNAS April 5, 2011 108 (14) 5504-5509; https://doi.org/10.1073/pnas.0911052108

Biological Sciences

  • Anthropology

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      Updated chronology for the Miocene hominoid radiation in Western Eurasia
      Isaac Casanovas-Vilar, David M. Alba, Miguel Garcés, Josep M. Robles, and Salvador Moyà-Solà
      PNAS April 5, 2011 108 (14) 5554-5559; https://doi.org/10.1073/pnas.1018562108
  • Biochemistry

    • Open Access
      Primordial synthesis of amines and amino acids in a 1958 Miller H2S-rich spark discharge experiment
      Eric T. Parker, Henderson J. Cleaves, Jason P. Dworkin, Daniel P. Glavin, Michael Callahan, Andrew Aubrey, Antonio Lazcano, and Jeffrey L. Bada
      PNAS April 5, 2011 108 (14) 5526-5531; https://doi.org/10.1073/pnas.1019191108
    • Open Access
      Ectopic B-cell clusters that infiltrate transplanted human kidneys are clonal
      Julong Cheng, Ali Torkamani, Rajesh K. Grover, Teresa M. Jones, Diana I. Ruiz, Nicholas J. Schork, Michael M. Quigley, F. Wesley Hall, Daniel R. Salomon, and Richard A. Lerner
      PNAS April 5, 2011 108 (14) 5560-5565; https://doi.org/10.1073/pnas.1101148108
    • You have access
      Proteomics approach to study the functions of Drosophila myosin VI through identification of multiple cargo-binding proteins
      • From the Cover
      Dina Finan, M. Amanda Hartman, and James A. Spudich
      PNAS April 5, 2011 108 (14) 5566-5571; https://doi.org/10.1073/pnas.1101415108

      See companion article:

      • Multifunctional myosin VI has a multitude of cargoes
        - Apr 04, 2011
    • Open Access
      Polycomb purification by in vivo biotinylation tagging reveals cohesin and Trithorax group proteins as interaction partners
      Gero Strübbe, Christian Popp, Alexander Schmidt, Andrea Pauli, Leonie Ringrose, Christian Beisel, and Renato Paro
      PNAS April 5, 2011 108 (14) 5572-5577; https://doi.org/10.1073/pnas.1007916108
    • You have access
      Cross-domain inhibition of TACE ectodomain
      Christopher J. Tape, Sofie H. Willems, Sarah L. Dombernowsky, Peter L. Stanley, Marton Fogarasi, Willem Ouwehand, John McCafferty, and Gillian Murphy
      PNAS April 5, 2011 108 (14) 5578-5583; https://doi.org/10.1073/pnas.1017067108
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      Heparan sulfate/heparin promotes transthyretin fibrillization through selective binding to a basic motif in the protein
      Fredrik Noborn, Paul O'Callaghan, Erik Hermansson, Xiao Zhang, John B. Ancsin, Ana M. Damas, Ingrid Dacklin, Jenny Presto, Jan Johansson, Maria J. Saraiva, Erik Lundgren, Robert Kisilevsky, Per Westermark, and Jin-Ping Li
      PNAS April 5, 2011 108 (14) 5584-5589; https://doi.org/10.1073/pnas.1101194108
    • Open Access
      E3 ligase Rad18 promotes monoubiquitination rather than ubiquitin chain formation by E2 enzyme Rad6
      Richard G. Hibbert, Anding Huang, Rolf Boelens, and Titia K. Sixma
      PNAS April 5, 2011 108 (14) 5590-5595; https://doi.org/10.1073/pnas.1017516108
  • Biophysics and Computational Biology

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      Growth, geometry, and mechanics of a blooming lily
      • From the Cover
      Haiyi Liang and L. Mahadevan
      PNAS April 5, 2011 108 (14) 5516-5521; https://doi.org/10.1073/pnas.1007808108
    • You have access
      Malleability of folding intermediates in the homeodomain superfamily
      Wiktor Banachewicz, Tomasz L. Religa, R. D. Schaeffer, Valerie Daggett, and Alan R. Fersht
      PNAS April 5, 2011 108 (14) 5596-5601; https://doi.org/10.1073/pnas.1101752108
    • You have access
      Assessing the fractions of tautomeric forms of the imidazole ring of histidine in proteins as a function of pH
      Jorge A. Vila, Yelena A. Arnautova, Yury Vorobjev, and Harold A. Scheraga
      PNAS April 5, 2011 108 (14) 5602-5607; https://doi.org/10.1073/pnas.1102373108
    • You have access
      Unsuspected pathway of the allosteric transition in hemoglobin
      Stefan Fischer, Kenneth W. Olsen, Kwangho Nam, and Martin Karplus
      PNAS April 5, 2011 108 (14) 5608-5613; https://doi.org/10.1073/pnas.1011995108
    • Open Access
      Dendritic cell chemotaxis in 3D under defined chemokine gradients reveals differential response to ligands CCL21 and CCL19
      Ulrike Haessler, Marco Pisano, Mingming Wu, and Melody A. Swartz
      PNAS April 5, 2011 108 (14) 5614-5619; https://doi.org/10.1073/pnas.1014920108
  • Cell Biology

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      Histone deacetylase inhibitor treatment dramatically reduces cholesterol accumulation in Niemann-Pick type C1 mutant human fibroblasts
      Nina H. Pipalia, Casey C. Cosner, Amy Huang, Anamitra Chatterjee, Pauline Bourbon, Nathan Farley, Paul Helquist, Olaf Wiest, and Frederick R. Maxfield
      PNAS April 5, 2011 108 (14) 5620-5625; https://doi.org/10.1073/pnas.1014890108
    • You have access
      Lsh, chromatin remodeling family member, modulates genome-wide cytosine methylation patterns at nonrepeat sequences
      Yongguang Tao, Sichuan Xi, Jigui Shan, Alika Maunakea, Anney Che, Victorino Briones, Eunice Y. Lee, Theresa Geiman, Jiaqiang Huang, Robert Stephens, Robert M. Leighty, Keji Zhao, and Kathrin Muegge
      PNAS April 5, 2011 108 (14) 5626-5631; https://doi.org/10.1073/pnas.1017000108
  • Developmental Biology

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      Co-occupancy by multiple cardiac transcription factors identifies transcriptional enhancers active in heart
      Aibin He, Sek Won Kong, Qing Ma, and William T. Pu
      PNAS April 5, 2011 108 (14) 5632-5637; https://doi.org/10.1073/pnas.1016959108
  • Ecology

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      Spatial characterization of the meltwater field from icebergs in the Weddell Sea
      John J. Helly, Ronald S. Kaufmann, Maria Vernet, and Gordon R. Stephenson
      PNAS April 5, 2011 108 (14) 5492-5497; https://doi.org/10.1073/pnas.0909306108
    • You have access
      A competitive network theory of species diversity
      Stefano Allesina and Jonathan M. Levine
      PNAS April 5, 2011 108 (14) 5638-5642; https://doi.org/10.1073/pnas.1014428108
    • You have access
      How frequency and intensity shape diversity–disturbance relationships
      Adam D. Miller, Stephen H. Roxburgh, and Katriona Shea
      PNAS April 5, 2011 108 (14) 5643-5648; https://doi.org/10.1073/pnas.1018594108
    • Open Access
      Diatoms respire nitrate to survive dark and anoxic conditions
      Anja Kamp, Dirk de Beer, Jana L. Nitsch, Gaute Lavik, and Peter Stief
      PNAS April 5, 2011 108 (14) 5649-5654; https://doi.org/10.1073/pnas.1015744108
  • Environmental Sciences

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      Eastern Equatorial Pacific productivity and related-CO2 changes since the last glacial period
      Eva Calvo, Carles Pelejero, Leopoldo D. Pena, Isabel Cacho, and Graham A. Logan
      PNAS April 5, 2011 108 (14) 5537-5541; https://doi.org/10.1073/pnas.1009761108
    • You have access
      Responses to historical climate change identify contemporary threats to diversity in Dodecatheon
      Brad Oberle and Barbara A. Schaal
      PNAS April 5, 2011 108 (14) 5655-5660; https://doi.org/10.1073/pnas.1012302108
  • Evolution

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      Estimate of effective recombination rate and average selection coefficient for HIV in chronic infection
      Rebecca Batorsky, Mary F. Kearney, Sarah E. Palmer, Frank Maldarelli, Igor M. Rouzine, and John M. Coffin
      PNAS April 5, 2011 108 (14) 5661-5666; https://doi.org/10.1073/pnas.1102036108
    • You have access
      Draft genome of the red harvester ant Pogonomyrmex barbatus
      Chris R. Smith, Christopher D. Smith, Hugh M. Robertson, Martin Helmkampf, Aleksey Zimin, Mark Yandell, Carson Holt, Hao Hu, Ehab Abouheif, Richard Benton, Elizabeth Cash, Vincent Croset, Cameron R. Currie, Eran Elhaik, Christine G. Elsik, Marie-Julie Favé, Vilaiwan Fernandes, Joshua D. Gibson, Dan Graur, Wulfila Gronenberg, Kirk J. Grubbs, Darren E. Hagen, Ana Sofia Ibarraran Viniegra, Brian R. Johnson, Reed M. Johnson, Abderrahman Khila, Jay W. Kim, Kaitlyn A. Mathis, Monica C. Munoz-Torres, Marguerite C. Murphy, Julie A. Mustard, Rin Nakamura, Oliver Niehuis, Surabhi Nigam, Rick P. Overson, Jennifer E. Placek, Rajendhran Rajakumar, Justin T. Reese, Garret Suen, Shu Tao, Candice W. Torres, Neil D. Tsutsui, Lumi Viljakainen, Florian Wolschin, and Jürgen Gadau
      PNAS April 5, 2011 108 (14) 5667-5672; https://doi.org/10.1073/pnas.1007901108

      See companion article:

      • The birth of ant genomics
        - Mar 28, 2011
    • Open Access
      Draft genome of the globally widespread and invasive Argentine ant (Linepithema humile)
      Christopher D. Smith, Aleksey Zimin, Carson Holt, Ehab Abouheif, Richard Benton, Elizabeth Cash, Vincent Croset, Cameron R. Currie, Eran Elhaik, Christine G. Elsik, Marie-Julie Fave, Vilaiwan Fernandes, Jürgen Gadau, Joshua D. Gibson, Dan Graur, Kirk J. Grubbs, Darren E. Hagen, Martin Helmkampf, Jo-Anne Holley, Hao Hu, Ana Sofia Ibarraran Viniegra, Brian R. Johnson, Reed M. Johnson, Abderrahman Khila, Jay W. Kim, Joseph Laird, Kaitlyn A. Mathis, Joseph A. Moeller, Monica C. Muñoz-Torres, Marguerite C. Murphy, Rin Nakamura, Surabhi Nigam, Rick P. Overson, Jennifer E. Placek, Rajendhran Rajakumar, Justin T. Reese, Hugh M. Robertson, Chris R. Smith, Andrew V. Suarez, Garret Suen, Elissa L. Suhr, Shu Tao, Candice W. Torres, Ellen van Wilgenburg, Lumi Viljakainen, Kimberly K. O. Walden, Alexander L. Wild, Mark Yandell, James A. Yorke, and Neil D. Tsutsui
      PNAS April 5, 2011 108 (14) 5673-5678; https://doi.org/10.1073/pnas.1008617108

      See companion article:

      • The birth of ant genomics
        - Mar 28, 2011
    • You have access
      The genome of the fire ant Solenopsis invicta
      Yannick Wurm, John Wang, Oksana Riba-Grognuz, Miguel Corona, Sanne Nygaard, Brendan G. Hunt, Krista K. Ingram, Laurent Falquet, Mingkwan Nipitwattanaphon, Dietrich Gotzek, Michiel B. Dijkstra, Jan Oettler, Fabien Comtesse, Cheng-Jen Shih, Wen-Jer Wu, Chin-Cheng Yang, Jerome Thomas, Emmanuel Beaudoing, Sylvain Pradervand, Volker Flegel, Erin D. Cook, Roberto Fabbretti, Heinz Stockinger, Li Long, William G. Farmerie, Jane Oakey, Jacobus J. Boomsma, Pekka Pamilo, Soojin V. Yi, Jürgen Heinze, Michael A. D. Goodisman, Laurent Farinelli, Keith Harshman, Nicolas Hulo, Lorenzo Cerutti, Ioannis Xenarios, DeWayne Shoemaker, and Laurent Keller
      PNAS April 5, 2011 108 (14) 5679-5684; https://doi.org/10.1073/pnas.1009690108

      See companion article:

      • The birth of ant genomics
        - Mar 28, 2011
    • You have access
      Tradeoffs associated with constitutive and induced plant resistance against herbivory
      Anne Kempel, Martin Schädler, Thomas Chrobock, Markus Fischer, and Mark van Kleunen
      PNAS April 5, 2011 108 (14) 5685-5689; https://doi.org/10.1073/pnas.1016508108
    • Open Access
      Episodic radiations in the fly tree of life
      Brian M. Wiegmann, Michelle D. Trautwein, Isaac S. Winkler, Norman B. Barr, Jung-Wook Kim, Christine Lambkin, Matthew A. Bertone, Brian K. Cassel, Keith M. Bayless, Alysha M. Heimberg, Benjamin M. Wheeler, Kevin J. Peterson, Thomas Pape, Bradley J. Sinclair, Jeffrey H. Skevington, Vladimir Blagoderov, Jason Caravas, Sujatha Narayanan Kutty, Urs Schmidt-Ott, Gail E. Kampmeier, F. Christian Thompson, David A. Grimaldi, Andrew T. Beckenbach, Gregory W. Courtney, Markus Friedrich, Rudolf Meier, and David K. Yeates
      PNAS April 5, 2011 108 (14) 5690-5695; https://doi.org/10.1073/pnas.1012675108
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      Stearoyl-acyl carrier protein desaturases are associated with floral isolation in sexually deceptive orchids
      Philipp M. Schlüter, Shuqing Xu, Valeria Gagliardini, Edward Whittle, John Shanklin, Ueli Grossniklaus, and Florian P. Schiestl
      PNAS April 5, 2011 108 (14) 5696-5701; https://doi.org/10.1073/pnas.1013313108
    • You have access
      Genetic basis of eye and pigment loss in the cave crustacean, Asellus aquaticus
      Meredith E. Protas, Peter Trontelj, and Nipam H. Patel
      PNAS April 5, 2011 108 (14) 5702-5707; https://doi.org/10.1073/pnas.1013850108
    • Open Access
      An evolutionary process that assembles phenotypes through space rather than through time
      Richard Shine, Gregory P. Brown, and Benjamin L. Phillips
      PNAS April 5, 2011 108 (14) 5708-5711; https://doi.org/10.1073/pnas.1018989108
  • Genetics

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      Direct regulation of Escherichia coli ribosomal protein promoters by the transcription factors ppGpp and DksA
      Justin J. Lemke, Patricia Sanchez-Vazquez, Hector L. Burgos, Gina Hedberg, Wilma Ross, and Richard L. Gourse
      PNAS April 5, 2011 108 (14) 5712-5717; https://doi.org/10.1073/pnas.1019383108
    • Open Access
      Lysine methyltransferase G9a is required for de novo DNA methylation and the establishment, but not the maintenance, of proviral silencing
      Danny C. Leung, Kevin B. Dong, Irina A. Maksakova, Preeti Goyal, Ruth Appanah, Sandra Lee, Makoto Tachibana, Yoichi Shinkai, Bernhard Lehnertz, Dixie L. Mager, Fabio Rossi, and Matthew C. Lorincz
      PNAS April 5, 2011 108 (14) 5718-5723; https://doi.org/10.1073/pnas.1014660108
  • Immunology

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      Single-cell gene-expression profiling reveals qualitatively distinct CD8 T cells elicited by different gene-based vaccines
      Lukas Flatz, Rahul Roychoudhuri, Mitsuo Honda, Abdelali Filali-Mouhim, Jean-Philippe Goulet, Nadia Kettaf, Min Lin, Mario Roederer, Elias K. Haddad, Rafick P. Sékaly, and Gary J. Nabel
      PNAS April 5, 2011 108 (14) 5724-5729; https://doi.org/10.1073/pnas.1013084108
    • Open Access
      Rv3615c is a highly immunodominant RD1 (Region of Difference 1)-dependent secreted antigen specific for Mycobacterium tuberculosis infection
      Kerry A. Millington, Sarah M. Fortune, Jeffrey Low, Alejandra Garces, Suzanne M. Hingley-Wilson, Melissa Wickremasinghe, Onn M. Kon, and Ajit Lalvani
      PNAS April 5, 2011 108 (14) 5730-5735; https://doi.org/10.1073/pnas.1015153108
    • You have access
      Innate immune genes synergize to predict increased risk of chronic disease in hepatitis C virus infection
      Megan M. Dring, Maria H. Morrison, Brian P. McSharry, Kieran J. Guinan, Richard Hagan, Irish HCV Research Consortium, Cliona O'Farrelly, and Clair M. Gardiner
      PNAS April 5, 2011 108 (14) 5736-5741; https://doi.org/10.1073/pnas.1016358108
  • Medical Sciences

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      Recombinant immunotoxin against B-cell malignancies with no immunogenicity in mice by removal of B-cell epitopes
      Masanori Onda, Richard Beers, Laiman Xiang, Byungkook Lee, John E. Weldon, Robert J. Kreitman, and Ira Pastan
      PNAS April 5, 2011 108 (14) 5742-5747; https://doi.org/10.1073/pnas.1102746108
    • Open Access
      Hepatic insulin resistance in mice with hepatic overexpression of diacylglycerol acyltransferase 2
      François R. Jornayvaz, Andreas L. Birkenfeld, Michael J. Jurczak, Shoichi Kanda, Blas A. Guigni, Debbie C. Jiang, Dongyan Zhang, Hui-Young Lee, Varman T. Samuel, and Gerald I. Shulman
      PNAS April 5, 2011 108 (14) 5748-5752; https://doi.org/10.1073/pnas.1103451108
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      Blockade of class IB phosphoinositide-3 kinase ameliorates obesity-induced inflammation and insulin resistance
      Naoki Kobayashi, Kohjiro Ueki, Yukiko Okazaki, Aya Iwane, Naoto Kubota, Mitsuru Ohsugi, Motoharu Awazawa, Masatoshi Kobayashi, Takayoshi Sasako, Kazuma Kaneko, Miho Suzuki, Yoshitaka Nishikawa, Kazuo Hara, Kotaro Yoshimura, Isao Koshima, Susumu Goyama, Koji Murakami, Junko Sasaki, Ryozo Nagai, Mineo Kurokawa, Takehiko Sasaki, and Takashi Kadowaki
      PNAS April 5, 2011 108 (14) 5753-5758; https://doi.org/10.1073/pnas.1016430108
    • You have access
      GPR124, an orphan G protein-coupled receptor, is required for CNS-specific vascularization and establishment of the blood–brain barrier
      Mike Cullen, Mohammed K. Elzarrad, Steven Seaman, Enrique Zudaire, Janine Stevens, Mi Young Yang, Xiujie Li, Amit Chaudhary, Lihong Xu, Mary Beth Hilton, Daniel Logsdon, Emily Hsiao, Erica V. Stein, Frank Cuttitta, Diana C. Haines, Kunio Nagashima, Lino Tessarollo, and Brad St. Croix
      PNAS April 5, 2011 108 (14) 5759-5764; https://doi.org/10.1073/pnas.1017192108
    • You have access
      A Sleeping Beauty transposon-mediated screen identifies murine susceptibility genes for adenomatous polyposis coli (Apc)-dependent intestinal tumorigenesis
      Timothy K. Starr, Patricia M. Scott, Benjamin M. Marsh, Lei Zhao, Bich L. N. Than, M. Gerard O'Sullivan, Aaron L. Sarver, Adam J. Dupuy, David A. Largaespada, and Robert T. Cormier
      PNAS April 5, 2011 108 (14) 5765-5770; https://doi.org/10.1073/pnas.1018012108
  • Microbiology

    • You have access
      Ordered assembly of murine leukemia virus capsid protein on lipid nanotubes directs specific binding by the restriction factor, Fv1
      Laura Hilditch, Rishi Matadeen, David C. Goldstone, Peter B. Rosenthal, Ian A. Taylor, and Jonathan P. Stoye
      PNAS April 5, 2011 108 (14) 5771-5776; https://doi.org/10.1073/pnas.1100118108
    • You have access
      Broad-spectrum antiviral that interferes with de novo pyrimidine biosynthesis
      Hans-Heinrich Hoffmann, Andrea Kunz, Viviana A. Simon, Peter Palese, and Megan L. Shaw
      PNAS April 5, 2011 108 (14) 5777-5782; https://doi.org/10.1073/pnas.1101143108
  • Neuroscience

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      Different nonlinear functions in hippocampus and perirhinal cortex relating functional MRI activity to memory strength
      Zhuang Song, John T. Wixted, Christine N. Smith, and Larry R. Squire
      PNAS April 5, 2011 108 (14) 5783-5788; https://doi.org/10.1073/pnas.1103225108
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      A sensory subpopulation depends on vesicular glutamate transporter 2 for mechanical pain, and together with substance P, inflammatory pain
      Malin C. Lagerström, Katarzyna Rogoz, Bjarke Abrahamsen, Anne-Li Lind, Caroline Ölund, Casey Smith, José Alfredo Mendez, Åsa Wallén-Mackenzie, John N. Wood, and Klas Kullander
      PNAS April 5, 2011 108 (14) 5789-5794; https://doi.org/10.1073/pnas.1013602108
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      Impaired NMDA receptor transmission alters striatal synapses and DISC1 protein in an age-dependent manner
      Amy J. Ramsey, Marija Milenkovic, Ana F. Oliveira, Yasmin Escobedo-Lozoya, Saurav Seshadri, Ali Salahpour, Akira Sawa, Ryohei Yasuda, and Marc G. Caron
      PNAS April 5, 2011 108 (14) 5795-5800; https://doi.org/10.1073/pnas.1012621108
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      Time-dependent corticosteroid modulation of prefrontal working memory processing
      Marloes J. A. G. Henckens, Guido A. van Wingen, Marian Joëls, and Guillén Fernández
      PNAS April 5, 2011 108 (14) 5801-5806; https://doi.org/10.1073/pnas.1019128108
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      Prospero-related homeobox 1 gene (Prox1) is regulated by canonical Wnt signaling and has a stage-specific role in adult hippocampal neurogenesis
      Özlem Karalay, Kathrin Doberauer, Krishna C. Vadodaria, Marlen Knobloch, Lucia Berti, Amaya Miquelajauregui, Manuela Schwark, Ravi Jagasia, Makoto M. Taketo, Victor Tarabykin, D. Chichung Lie, and Sebastian Jessberger
      PNAS April 5, 2011 108 (14) 5807-5812; https://doi.org/10.1073/pnas.1013456108
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      Interaction between hypothalamic dorsomedial nucleus and the suprachiasmatic nucleus determines intensity of food anticipatory behavior
      Guadalupe Acosta-Galvan, Chun-Xia Yi, Jan van der Vliet, Jack H. Jhamandas, Pertti Panula, Manuel Angeles-Castellanos, María del Carmen Basualdo, Carolina Escobar, and Ruud M. Buijs
      PNAS April 5, 2011 108 (14) 5813-5818; https://doi.org/10.1073/pnas.1015551108
    • Open Access
      Soluble amyloid β-protein dimers isolated from Alzheimer cortex directly induce Tau hyperphosphorylation and neuritic degeneration
      Ming Jin, Nina Shepardson, Ting Yang, Gang Chen, Dominic Walsh, and Dennis J. Selkoe
      PNAS April 5, 2011 108 (14) 5819-5824; https://doi.org/10.1073/pnas.1017033108
    • Open Access
      Usher type 1G protein sans is a critical component of the tip-link complex, a structure controlling actin polymerization in stereocilia
      Elisa Caberlotto, Vincent Michel, Isabelle Foucher, Amel Bahloul, Richard J. Goodyear, Elise Pepermans, Nicolas Michalski, Isabelle Perfettini, Olinda Alegria-Prévot, Sébastien Chardenoux, Marcio Do Cruzeiro, Jean-Pierre Hardelin, Guy P. Richardson, Paul Avan, Dominique Weil, and Christine Petit
      PNAS April 5, 2011 108 (14) 5825-5830; https://doi.org/10.1073/pnas.1017114108
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      Mechanism underlying selective regulation of G protein-gated inwardly rectifying potassium channels by the psychostimulant-sensitive sorting nexin 27
      Bartosz Balana, Innokentiy Maslennikov, Witek Kwiatkowski, Kalyn M. Stern, Laia Bahima, Senyon Choe, and Paul A. Slesinger
      PNAS April 5, 2011 108 (14) 5831-5836; https://doi.org/10.1073/pnas.1018645108
    • Open Access
      Cell cycle restriction by histone H2AX limits proliferation of adult neural stem cells
      Ruani N. Fernando, Boris Eleuteri, Shaimaa Abdelhady, Andre Nussenzweig, Michael Andäng, and Patrik Ernfors
      PNAS April 5, 2011 108 (14) 5837-5842; https://doi.org/10.1073/pnas.1014993108
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      Timescale-dependent shaping of correlation by olfactory bulb lateral inhibition
      Sonya Giridhar, Brent Doiron, and Nathaniel N. Urban
      PNAS April 5, 2011 108 (14) 5843-5848; https://doi.org/10.1073/pnas.1015165108
    • Open Access
      AMP-activated protein kinase (AMPK) activity is not required for neuronal development but regulates axogenesis during metabolic stress
      Tyisha Williams, Julien Courchet, Benoit Viollet, Jay E. Brenman, and Franck Polleux
      PNAS April 5, 2011 108 (14) 5849-5854; https://doi.org/10.1073/pnas.1013660108
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      NMDA receptor subunit composition controls synaptogenesis and synapse stabilization
      Abigail C. Gambrill and Andres Barria
      PNAS April 5, 2011 108 (14) 5855-5860; https://doi.org/10.1073/pnas.1012676108
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      Disrupted-in-Schizophrenia 1–mediated axon guidance involves TRIO-RAC-PAK small GTPase pathway signaling
      Shih-Yu Chen, Pei-Hsin Huang, and Hwai-Jong Cheng
      PNAS April 5, 2011 108 (14) 5861-5866; https://doi.org/10.1073/pnas.1018128108
  • Pharmacology

    • Open Access
      Agonist activation of α7 nicotinic acetylcholine receptors via an allosteric transmembrane site
      JasKiran K. Gill, Mari Savolainen, Gareth T. Young, Ruud Zwart, Emanuele Sher, and Neil S. Millar
      PNAS April 5, 2011 108 (14) 5867-5872; https://doi.org/10.1073/pnas.1017975108
  • Physiology

    • Open Access
      Calmodulin protects against alcohol-induced pancreatic trypsinogen activation elicited via Ca2+ release through IP3 receptors
      Julia V. Gerasimenko, György Lur, Pawel Ferdek, Mark W. Sherwood, Etsuko Ebisui, Alexei V. Tepikin, Katsuhiko Mikoshiba, Ole H. Petersen, and Oleg V. Gerasimenko
      PNAS April 5, 2011 108 (14) 5873-5878; https://doi.org/10.1073/pnas.1016534108
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      Deletion of the Slo3 gene abolishes alkalization-activated K+ current in mouse spermatozoa
      Xu-Hui Zeng, Chengtao Yang, Sung Tae Kim, Christopher J. Lingle, and Xiao-Ming Xia
      PNAS April 5, 2011 108 (14) 5879-5884; https://doi.org/10.1073/pnas.1100240108
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      Oxidation of NADPH on Kvβ1 inhibits ball-and-chain type inactivation by restraining the chain
      Yaping Pan, Jun Weng, Elena J. Levin, and Ming Zhou
      PNAS April 5, 2011 108 (14) 5885-5890; https://doi.org/10.1073/pnas.1100316108
  • Plant Biology

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      Jasmonate signaling involves the abscisic acid receptor PYL4 to regulate metabolic reprogramming in Arabidopsis and tobacco
      Petri Lackman, Miguel González-Guzmán, Sofie Tilleman, Inês Carqueijeiro, Amparo Cuéllar Pérez, Tessa Moses, Mitsunori Seo, Yuri Kanno, Suvi T. Häkkinen, Marc C. E. Van Montagu, Johan M. Thevelein, Hannu Maaheimo, Kirsi-Marja Oksman-Caldentey, Pedro L. Rodriguez, Heiko Rischer, and Alain Goossens
      PNAS April 5, 2011 108 (14) 5891-5896; https://doi.org/10.1073/pnas.1103010108
    • You have access
      Adaptive evolution of threonine deaminase in plant defense against insect herbivores
      Eliana Gonzales-Vigil, Christopher M. Bianchetti, George N. Phillips Jr., and Gregg A. Howe
      PNAS April 5, 2011 108 (14) 5897-5902; https://doi.org/10.1073/pnas.1016157108
  • Psychological and Cognitive Sciences

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      Fidelity of neural reactivation reveals competition between memories
      Brice A. Kuhl, Jesse Rissman, Marvin M. Chun, and Anthony D. Wagner
      PNAS April 5, 2011 108 (14) 5903-5908; https://doi.org/10.1073/pnas.1016939108
  • Sustainability Science

    • Open Access
      Global growth and stability of agricultural yield decrease with pollinator dependence
      Lucas A. Garibaldi, Marcelo A. Aizen, Alexandra M. Klein, Saul A. Cunningham, and Lawrence D. Harder
      PNAS April 5, 2011 108 (14) 5909-5914; https://doi.org/10.1073/pnas.1012431108
  • Systems Biology

    • You have access
      Statistical image analysis reveals features affecting fates of Myxococcus xanthus developmental aggregates
      Chunyan Xie, Haiyang Zhang, Lawrence J. Shimkets, and Oleg A. Igoshin
      PNAS April 5, 2011 108 (14) 5915-5920; https://doi.org/10.1073/pnas.1018383108

Corrections

  • You have access
    Correction for Moskowitz et al., Cardiac-specific transcription factor genes Smad4 and Gata4 cooperatively regulate cardiac valve development
    PNAS April 5, 2011 108 (14) 5921; https://doi.org/10.1073/pnas.1103973108
  • You have access
    Correction for Cao et al., Irradiation induces bone injury by damaging bone marrow microenvironment for stem cells
    PNAS April 5, 2011 108 (14) 5921; https://doi.org/10.1073/pnas.1104040108
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Proceedings of the National Academy of Sciences: 108 (14)
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