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Table of Contents
May 31, 2011; vol. 108 no. 22
This Week in PNAS
Letters (Online Only)
- You have accessReply to Collins and Copeland: Spontaneous gelatinization not supported by evidenceAmanda G. Henry, Alison S. Brooks, and Dolores R. Piperno
- You have accessReply to Dyke and Naish: European alvarezsauroids do not change the pictureXing Xu, Corwin Sullivan, Michael Pittman, Jonah N. Choiniere, David Hone, Paul Upchurch, Qingwei Tan, Dong Xiao, Lin Tan, and Fenglu Han
PNAS Plus (Author Summaries and Research Articles)
Biological Sciences
Biochemistry
- Open AccessGenome-wide remodeling of the epigenetic landscape during myogenic differentiationPatrik Asp, Roy Blum, Vasupradha Vethantham, Fabio Parisi, Mariann Micsinai, Jemmie Cheng, Christopher Bowman, Yuval Kluger, and Brian David Dynlacht
See companion article:
- You have accessBromodomain protein Brd3 associates with acetylated GATA1 to promote its chromatin occupancy at erythroid target genesJanine M. Lamonica, Wulan Deng, Stephan Kadauke, Amy E. Campbell, Roland Gamsjaeger, Hongxin Wang, Yong Cheng, Andrew N. Billin, Ross C. Hardison, Joel P. Mackay, and Gerd A. Blobel
Biophysics and Computational Biology
- You have accessIntra- and intermolecular translocation of the bi-domain transcription factor Oct1 characterized by liquid crystal and paramagnetic NMRYuki Takayama and G. Marius Clore
See companion article:
Environmental Sciences
- You have accessTracking Baltic hypoxia and cod migration over millennia with natural tagsKarin E. Limburg, Carina Olson, Yvonne Walther, Darren Dale, Caroline P. Slomp, and Hans Høie
See companion article:
Neuroscience
- You have accessTargeted mini-strokes produce changes in interhemispheric sensory signal processing that are indicative of disinhibition within minutesMajid H. Mohajerani, Khatereh Aminoltejari, and Timothy H. Murphy
See companion article:
Profile
Physical Sciences
Applied Physical Sciences
- You have accessElectrokinetic trapping at the one nanometer limitAlexander P. Fields and Adam E. Cohen
- You have accessDeep-tissue anatomical imaging of mice using carbon nanotube fluorophores in the second near-infrared windowKevin Welsher, Sarah P. Sherlock, and Hongjie Dai
- You have accessIntegrin adhesion drives the emergent polarization of active cytoskeletal stresses to pattern cell delaminationC. Meghana, Nisha Ramdas, Feroz Meeran Hameed, Madan Rao, G. V. Shivashankar, and Maithreyi Narasimha
- Open AccessMinimally invasive molecular delivery into the brain using optical modulation of vascular permeabilityMyunghwan Choi, Taeyun Ku, Kyuha Chong, Jonghee Yoon, and Chulhee Choi
Chemistry
- You have accessOrigins of saccharide-dependent hydration at aluminate, silicate, and aluminosilicate surfacesBenjamin J. Smith, Aditya Rawal, Gary P. Funkhouser, Lawrence R. Roberts, Vijay Gupta, Jacob N. Israelachvili, and Bradley F. Chmelka
- You have accessBreaking the regioselectivity rule for acrylate insertion in the Mizoroki–Heck reactionPhilipp Wucher, Lucia Caporaso, Philipp Roesle, Francesco Ragone, Luigi Cavallo, Stefan Mecking, and Inigo Göttker-Schnetmann
Engineering
- Open AccessRole of design complexity in technology improvementJames McNerney, J. Doyne Farmer, Sidney Redner, and Jessika E. Trancik
Environmental Sciences
- You have accessImpacts of a recent storm surge on an Arctic delta ecosystem examined in the context of the last millenniumMichael F. J. Pisaric, Joshua R. Thienpont, Steven V. Kokelj, Holly Nesbitt, Trevor C. Lantz, Steven Solomon, and John P. Smol
- You have accessIsocyanic acid in the atmosphere and its possible link to smoke-related health effects
- From the Cover
James M. Roberts, Patrick R. Veres, Anthony K. Cochran, Carsten Warneke, Ian R. Burling, Robert J. Yokelson, Brian Lerner, Jessica B. Gilman, William C. Kuster, Ray Fall, and Joost de Gouw
Geology
- You have accessClimatically driven biogeographic provinces of Late Triassic tropical PangeaJessica H. Whiteside, Danielle S. Grogan, Paul E. Olsen, and Dennis V. Kent
- You have accessIsotopic Ag–Cu–Pb record of silver circulation through 16th–18th century Spain
- From the Cover
Anne-Marie Desaulty, Philippe Telouk, Emmanuelle Albalat, and Francis Albarède
Geophysics
- You have accessCommitted sea-level rise for the next century from Greenland ice sheet dynamics during the past decadeStephen F. Price, Antony J. Payne, Ian M. Howat, and Benjamin E. Smith
Mathematics
- You have accessKP solitons, total positivity, and cluster algebrasYuji Kodama and Lauren K. Williams
Physics
- Open AccessTwo-phase dynamics of p53 in the DNA damage responseXiao-Peng Zhang, Feng Liu, and Wei Wang
- You have accessDiscontinuous shear thickening in confined dilute carbon nanotube suspensionsSayantan Majumdar, Rema Krishnaswamy, and A. K. Sood
Social Sciences
Anthropology
- You have accessIsotopic Ag–Cu–Pb record of silver circulation through 16th–18th century Spain
- From the Cover
Anne-Marie Desaulty, Philippe Telouk, Emmanuelle Albalat, and Francis Albarède
Economic Sciences
- Open AccessRole of design complexity in technology improvementJames McNerney, J. Doyne Farmer, Sidney Redner, and Jessika E. Trancik
Psychological and Cognitive Sciences
- You have accessHow words can and cannot be learned by observationTamara Nicol Medina, Jesse Snedeker, John C. Trueswell, and Lila R. Gleitman
Social Sciences
- Open AccessHow social influence can undermine the wisdom of crowd effectJan Lorenz, Heiko Rauhut, Frank Schweitzer, and Dirk Helbing
Biological Sciences
Applied Biological Sciences
- Open AccessCounting individual DNA molecules by the stochastic attachment of diverse labelsGlenn K. Fu, Jing Hu, Pei-Hua Wang, and Stephen P. A. Fodor
- You have accessIn vivo fluorescence imaging of exogenous enzyme activity in the gastrointestinal tractGregor Fuhrmann and Jean-Christophe Leroux
Biochemistry
- You have accessSoluble epoxide hydrolase deficiency alters pancreatic islet size and improves glucose homeostasis in a model of insulin resistanceAyala Luria, Ahmed Bettaieb, Yannan Xi, Guang-Jong Shieh, Hsin-Chen Liu, Hiromi Inoue, Hsing-Ju Tsai, John D. Imig, Fawaz G. Haj, and Bruce D. Hammock
- Open AccessRegulation of human EGF receptor by lipidsÜnal Coskun, Michał Grzybek, David Drechsel, and Kai Simons
- You have accessPeptide surfactants for cell-free production of functional G protein-coupled receptorsXiaoqiang Wang, Karolina Corin, Philipp Baaske, Christoph J. Wienken, Moran Jerabek-Willemsen, Stefan Duhr, Dieter Braun, and Shuguang Zhang
- You have accessStructural insight into maintenance methylation by mouse DNA methyltransferase 1 (Dnmt1)
- From the Cover
Kohei Takeshita, Isao Suetake, Eiki Yamashita, Michihiro Suga, Hirotaka Narita, Atsushi Nakagawa, and Shoji TajimaSee companion article:
- Twists and turns of DNA methylation- May 18, 2011
- You have accessOptimized clinical performance of growth hormone with an expanded genetic codeHo Cho, Tom Daniel, Ying Ji Buechler, David C. Litzinger, Zhenwei Maio, Anna-Maria Hays Putnam, Vadim S. Kraynov, Bee-Cheng Sim, Stuart Bussell, Tsotne Javahishvili, Sami Kaphle, Guillermo Viramontes, Mike Ong, Stephanie Chu, Becky GC, Ricky Lieu, Nick Knudsen, Paola Castiglioni, Thea C. Norman, Douglas W. Axelrod, Andrew R. Hoffman, Peter G. Schultz, Richard D. DiMarchi, and Bruce E. Kimmel
- You have accessAgonist trapped in ATP-binding sites of the P2X2 receptorRuotian Jiang, Damien Lemoine, Adeline Martz, Antoine Taly, Sophie Gonin, Lia Prado de Carvalho, Alexandre Specht, and Thomas Grutter
- You have accessInhibition of autoprocessing of natural variants and multidrug resistant mutant precursors of HIV-1 protease by clinical inhibitorsJohn M. Louis, Annie Aniana, Irene T. Weber, and Jane M. Sayer
Biophysics and Computational Biology
- Open AccessTwo-phase dynamics of p53 in the DNA damage responseXiao-Peng Zhang, Feng Liu, and Wei Wang
- You have accessMeasurement of protein unfolding/refolding kinetics and structural characterization of hidden intermediates by NMR relaxation dispersionDerrick W. Meinhold and Peter E. Wright
- You have accessMechanics of surface area regulation in cells examined with confined lipid membranesMargarita Staykova, Douglas P. Holmes, Clarke Read, and Howard A. Stone
- You have accessT-cell triggering thresholds are modulated by the number of antigen within individual T-cell receptor clustersBoryana N. Manz, Bryan L. Jackson, Rebecca S. Petit, Michael L. Dustin, and Jay Groves
- You have accessKCNE1 enhances phosphatidylinositol 4,5-bisphosphate (PIP2) sensitivity of IKs to modulate channel activityYang Li, Mark A. Zaydman, Dick Wu, Jingyi Shi, Michael Guan, Brett Virgin-Downey, and Jianmin Cui
- You have accessStructural topology of phospholamban pentamer in lipid bilayers by a hybrid solution and solid-state NMR methodRaffaello Verardi, Lei Shi, Nathaniel J. Traaseth, Naomi Walsh, and Gianluigi Veglia
Cell Biology
- You have accessIntegrin adhesion drives the emergent polarization of active cytoskeletal stresses to pattern cell delaminationC. Meghana, Nisha Ramdas, Feroz Meeran Hameed, Madan Rao, G. V. Shivashankar, and Maithreyi Narasimha
- You have accessCell-free sorting of peroxisomal membrane proteins from the endoplasmic reticulumGaurav Agrawal, Saurabh Joshi, and Suresh Subramani
- You have accessUbiquitin-recognition protein Ufd1 couples the endoplasmic reticulum (ER) stress response to cell cycle controlMeifan Chen, Gustavo J. Gutierrez, and Ze'ev A. Ronai
Developmental Biology
- Open AccessPhosphorylation state of a Tob/BTG protein, FOG-3, regulates initiation and maintenance of the Caenorhabditis elegans sperm fate programMyon-Hee Lee, Kyung Won Kim, Clinton T. Morgan, Dyan E. Morgan, and Judith Kimble
- You have accessDoublesex and mab-3–related transcription factor 5 promotes midbrain dopaminergic identity in pluripotent stem cells by enforcing a ventral-medial progenitor fateNicole Gennet, Emily Gale, Xinsheng Nan, Emma Farley, Katalin Takacs, Barbara Oberwallner, David Chambers, and Meng Li
- Open AccessAutoregulatory and repressive inputs localize Hydra Wnt3 to the head organizerYukio Nakamura, Charisios D. Tsiairis, Suat Özbek, and Thomas W. Holstein
- Open AccessDirect development of neurons within foregut endoderm of sea urchin embryosZheng Wei, Robert C. Angerer, and Lynne M. Angerer
Ecology
- You have accessImpacts of a recent storm surge on an Arctic delta ecosystem examined in the context of the last millenniumMichael F. J. Pisaric, Joshua R. Thienpont, Steven V. Kokelj, Holly Nesbitt, Trevor C. Lantz, Steven Solomon, and John P. Smol
- You have accessHyperspectral imaging of cuttlefish camouflage indicates good color match in the eyes of fish predatorsChuan-Chin Chiao, J. Kenneth Wickiser, Justine J. Allen, Brock Genter, and Roger T. Hanlon
Evolution
- You have accessClimatically driven biogeographic provinces of Late Triassic tropical PangeaJessica H. Whiteside, Danielle S. Grogan, Paul E. Olsen, and Dennis V. Kent
- You have accessEvolution of sodium channels predates the origin of nervous systems in animalsBenjamin J. Liebeskind, David M. Hillis, and Harold H. Zakon
- You have accessAmphioxus FGF signaling predicts the acquisition of vertebrate morphological traitsStephanie Bertrand, Alain Camasses, Ildiko Somorjai, Mohamed R. Belgacem, Olivier Chabrol, Marie-Line Escande, Pierre Pontarotti, and Hector Escriva
Genetics
- Open AccessObligate biotrophy features unraveled by the genomic analysis of rust fungi
- From the Cover
Sébastien Duplessis, Christina A. Cuomo, Yao-Cheng Lin, Andrea Aerts, Emilie Tisserant, Claire Veneault-Fourrey, David L. Joly, Stéphane Hacquard, Joëlle Amselem, Brandi L. Cantarel, Readman Chiu, Pedro M. Coutinho, Nicolas Feau, Matthew Field, Pascal Frey, Eric Gelhaye, Jonathan Goldberg, Manfred G. Grabherr, Chinnappa D. Kodira, Annegret Kohler, Ursula Kües, Erika A. Lindquist, Susan M. Lucas, Rohit Mago, Evan Mauceli, Emmanuelle Morin, Claude Murat, Jasmyn L. Pangilinan, Robert Park, Matthew Pearson, Hadi Quesneville, Nicolas Rouhier, Sharadha Sakthikumar, Asaf A. Salamov, Jeremy Schmutz, Benjamin Selles, Harris Shapiro, Philippe Tanguay, Gerald A. Tuskan, Bernard Henrissat, Yves Van de Peer, Pierre Rouzé, Jeffrey G. Ellis, Peter N. Dodds, Jacqueline E. Schein, Shaobin Zhong, Richard C. Hamelin, Igor V. Grigoriev, Les J. Szabo, and Francis MartinSee companion article:
- You have accessRecurrent chimeric RNAs enriched in human prostate cancer identified by deep sequencingKalpana Kannan, Liguo Wang, Jianghua Wang, Michael M. Ittmann, Wei Li, and Laising Yen
Immunology
- You have accessSystematic identification of immunodominant CD8+ T-cell responses to influenza A virus in HLA-A2 individualsChao Wu, Damien Zanker, Sophie Valkenburg, Bee Tan, Katherine Kedzierska, Quan Ming Zou, Peter C. Doherty, and Weisan Chen
- You have accessNF-κB dysregulation in microRNA-146a–deficient mice drives the development of myeloid malignanciesJimmy L. Zhao, Dinesh S. Rao, Mark P. Boldin, Konstantin D. Taganov, Ryan M. O'Connell, and David Baltimore
- Open AccessImmune surveillance by mast cells during dengue infection promotes natural killer (NK) and NKT-cell recruitment and viral clearanceAshley L. St. John, Abhay P. S. Rathore, Han Yap, Mah-Lee Ng, Dean D. Metcalfe, Subhash G. Vasudevan, and Soman N. Abraham
- You have accessControl of Toxoplasma reactivation by rescue of dysfunctional CD8+ T-cell response via PD-1–PDL-1 blockadeRajarshi Bhadra, Jason P. Gigley, Louis M. Weiss, and Imtiaz A. Khan
Medical Sciences
- You have accessRole of low-frequency HIV-1 variants in failure of nevirapine-containing antiviral therapy in women previously exposed to single-dose nevirapineValerie F. Boltz, Yu Zheng, Shahin Lockman, Feiyu Hong, Elias K. Halvas, James McIntyre, Judith S. Currier, Margret C. Chibowa, Cecelia Kanyama, Apsara Nair, Willis Owino-Ong'or, Michael Hughes, John M. Coffin, and John W. Mellors
- You have accessThermodynamic stability of small hairpin RNAs highly influences the loading process of different mammalian ArgonautesShuo Gu, Lan Jin, Feijie Zhang, Yong Huang, Dirk Grimm, John J. Rossi, and Mark A. Kay
- You have accessDecellularized tissue-engineered blood vessel as an arterial conduitClay Quint, Yuka Kondo, Roberto J. Manson, Jeffrey H. Lawson, Alan Dardik, and Laura E. Niklason
- You have accessRegulation of type 17 helper T-cell function by nitric oxide during inflammationWanda Niedbala, Jose C. Alves-Filho, Sandra Y. Fukada, Silvio Manfredo Vieira, Akio Mitani, Fabiane Sonego, Ananda Mirchandani, Daniele C. Nascimento, Fernando Q. Cunha, and Foo Y. Liew
- You have accessRepair of injured proximal tubule does not involve specialized progenitorsBenjamin D. Humphreys, Suzanne Czerniak, Derek P. DiRocco, Wirasat Hasnain, Rabia Cheema, and Joseph V. Bonventre
- You have accessmiR-33a/b contribute to the regulation of fatty acid metabolism and insulin signalingAlberto Dávalos, Leigh Goedeke, Peter Smibert, Cristina M. Ramírez, Nikhil P. Warrier, Ursula Andreo, Daniel Cirera-Salinas, Katey Rayner, Uthra Suresh, José Carlos Pastor-Pareja, Enric Esplugues, Edward A. Fisher, Luiz O. F. Penalva, Kathryn J. Moore, Yajaira Suárez, Eric C. Lai, and Carlos Fernández-Hernando
Microbiology
- Open AccessHelicobacter pylori cytotoxin-associated gene A (CagA) subverts the apoptosis-stimulating protein of p53 (ASPP2) tumor suppressor pathway of the hostLudovico Buti, Eric Spooner, Annemarthe G. Van der Veen, Rino Rappuoli, Antonello Covacci, and Hidde L. Ploegh
- You have accessHIV DNA is heavily uracilated, which protects it from autointegrationNan Yan, Elizabeth O'Day, Lee Adam Wheeler, Alan Engelman, and Judy Lieberman
- You have accessWolbachia uses host microRNAs to manipulate host gene expression and facilitate colonization of the dengue vector Aedes aegyptiMazhar Hussain, Francesca D. Frentiu, Luciano A. Moreira, Scott L. O'Neill, and Sassan Asgari
Neuroscience
- Open AccessMinimally invasive molecular delivery into the brain using optical modulation of vascular permeabilityMyunghwan Choi, Taeyun Ku, Kyuha Chong, Jonghee Yoon, and Chulhee Choi
- You have accessAntidepressant effects of selective serotonin reuptake inhibitors (SSRIs) are attenuated by antiinflammatory drugs in mice and humans
- From the Cover
Jennifer L. Warner-Schmidt, Kimberly E. Vanover, Emily Y. Chen, John J. Marshall, and Paul GreengardSee companion article:
- Serotonin, cytokines, p11, and depression- May 18, 2011
- You have accessHuman Mu Opioid Receptor (OPRM1 A118G) polymorphism is associated with brain mu-opioid receptor binding potential in smokersRiju Ray, Kosha Ruparel, Andrew Newberg, E. Paul Wileyto, James W. Loughead, Chaitanya Divgi, Julie A. Blendy, Jean Logan, Jon-Kar Zubieta, and Caryn Lerman
- You have accessGenetic analysis of age-dependent defects of the Caenorhabditis elegans touch receptor neuronsChun-Liang Pan, Chiu-Ying Peng, Chun-Hao Chen, and Steven McIntire
- You have accessChanges in striatal procedural memory coding correlate with learning deficits in a mouse model of Huntington diseaseSebastien Cayzac, Sebastien Delcasso, Vietminh Paz, Yannick Jeantet, and Yoon H. Cho
Plant Biology
- Open AccessThe Arabidopsis flagellin receptor FLS2 mediates the perception of Xanthomonas Ax21 secreted peptidesCristian H. Danna, Yves A. Millet, Teresa Koller, Sang-Wook Han, Andrew F. Bent, Pamela C. Ronald, and Frederick M. Ausubel
- You have accessCircadian oscillation of gibberellin signaling in ArabidopsisMaría Verónica Arana, Nora Marín-de la Rosa, Julin N. Maloof, Miguel A. Blázquez, and David Alabadí
- You have accessCytochrome P450 CYP94B3 mediates catabolism and inactivation of the plant hormone jasmonoyl-L-isoleucineAbraham J. K. Koo, Thomas F. Cooke, and Gregg A. Howe
Psychological and Cognitive Sciences
- Open AccessHow social influence can undermine the wisdom of crowd effectJan Lorenz, Heiko Rauhut, Frank Schweitzer, and Dirk Helbing
Sustainability Science
- Open AccessGenetic and expression analysis of cattle identifies candidate genes in pathways responding to Trypanosoma congolense infectionHarry Noyes, Andy Brass, Isaiah Obara, Susan Anderson, Alan L. Archibald, Dan G. Bradley, Paul Fisher, Abigail Freeman, John Gibson, Michael Gicheru, Laurence Hall, Olivier Hanotte, Helen Hulme, Declan McKeever, Caitriona Murray, Sung Jung Oh, Catriona Tate, Ken Smith, Miika Tapio, John Wambugu, Diana J. Williams, Morris Agaba, and Stephen J. Kemp
Systems Biology
- Open AccessContinuous polo-like kinase 1 activity regulates diffusion to maintain centrosome self-organization during mitosisRobert Mahen, Anand D. Jeyasekharan, Nicholas P. Barry, and Ashok R. Venkitaraman
Commentaries
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