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Evolution of sodium channels predates the origin of nervous systems in animals
Contributed by David M. Hillis, April 21, 2011 (sent for review February 15, 2011)

Online Impact
Article Information
- Published in issue May 31, 2011.
- Published first May 16, 2011.
Author Information
- aSection of Integrative Biology and Center for Computational Biology and Bioinformatics and
- bSection of Neurobiology, University of Texas, Austin, TX 78712; and
- cJosephine Bay Paul Center, Marine Biological Laboratory, Woods Hole, MA 02543
Contributed by David M. Hillis, April 21, 2011 (sent for review February 15, 2011)
Footnotes
- 1To whom correspondence may be addressed. E-mail: h.zakon{at}mail.utexas.edu or dhillis{at}mail.utexas.edu.
Author contributions: H.H.Z. designed research; B.J.L. and H.H.Z. performed research; B.J.L., D.M.H., and H.H.Z. analyzed data; and B.J.L., D.M.H., and H.H.Z. wrote the paper.
The authors declare no conflict of interest.
Data deposition: Accession numbers and relevant databases are provided in Table S1. The sequences reported in this paper have been deposited in the GenBank database (accession nos. JF827087, JF905561, JF905562 and JF905563).
This article contains supporting information online at www.pnas.org/lookup/suppl/doi:10.1073/pnas.1106363108/-/DCSupplemental.
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